TreeWAS – Variant ID: rs7423615

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C91.1 Chronic lymphocytic leukaemia	0.629	0.371	0.000
C91 Lymphoid leukaemia	0.511	0.489	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.458	0.542	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.445	0.555	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.414	0.586	0.000
C83.0 Small cell (diffuse)	0.405	0.595	0.000
C95 Leukaemia of unspecified cell type	0.400	0.600	0.000
C91.0 Acute lymphoblastic leukaemia	0.398	0.602	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.392	0.608	0.000
C81 Hodgkin's disease	0.386	0.614	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.367	0.633	0.000
C91.7 Other lymphoid leukaemia	0.367	0.633	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.367	0.633	0.000
C91.5 Adult T-cell leukaemia	0.367	0.633	0.000
C91.3 Prolymphocytic leukaemia	0.367	0.633	0.000
C91.2 Subacute lymphocytic leukaemia	0.367	0.633	0.000
C83.7 Burkitt's tumour	0.365	0.635	0.000
C83.1 Small cleaved cell (diffuse)	0.362	0.638	0.000
C95.9 Leukaemia, unspecified	0.358	0.642	0.000
C91.9 Lymphoid leukaemia, unspecified	0.344	0.656	0.000
C88 Malignant immunoproliferative diseases	0.337	0.663	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.329	0.671	0.000
C94 Other leukaemias of specified cell type	0.329	0.671	0.000
C86 Other specified types of T/NK-cell lymphoma	0.329	0.671	0.000
C81.1 Nodular sclerosis	0.328	0.672	0.000
C92 Myeloid leukaemia	0.325	0.675	0.000
C90.2 Plasmacytoma, extramedullary	0.323	0.677	0.000
C83.6 Undifferentiated (diffuse)	0.319	0.681	0.000
C83.5 Lymphoblastic (diffuse)	0.319	0.681	0.000
C83.4 Immunoblastic (diffuse)	0.319	0.681	0.000
C83.2 Mixed small and large cell (diffuse)	0.319	0.681	0.000
C93 Monocytic leukaemia	0.318	0.682	0.000
C90.3 Solitary plasmacytoma	0.311	0.689	0.000
C81.0 Lymphocytic predominance	0.303	0.697	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.294	0.706	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.293	0.707	0.000
C90.0 Multiple myeloma	0.290	0.710	0.000
C95.7 Other leukaemia of unspecified cell type	0.287	0.713	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.287	0.713	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.287	0.713	0.000
C95.0 Acute leukaemia of unspecified cell type	0.287	0.713	0.000
C90.1 Plasma cell leukaemia	0.281	0.718	0.000
C92.0 Acute myeloid leukaemia	0.280	0.720	0.000
C81.7 Other Hodgkin's disease	0.277	0.723	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.277	0.723	0.000
C81.3 Lymphocytic depletion	0.277	0.723	0.000
C81.2 Mixed cellularity	0.277	0.723	0.000
C91.4 Hairy-cell leukaemia	0.259	0.741	0.000
C81.9 Hodgkin's disease, unspecified	0.257	0.743	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.255	0.745	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.242	0.758	0.000
C88.7 Other malignant immunoproliferative diseases	0.242	0.758	0.000
C88.3 Immunoproliferative small intestinal disease	0.242	0.758	0.000
C88.2 Gamma heavy chain disease	0.242	0.758	0.000
C88.1 Alpha heavy chain disease	0.242	0.758	0.000
C92.7 Other myeloid leukaemia	0.239	0.761	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.236	0.764	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.236	0.764	0.000
C86.4 Blastic NK-cell lymphoma	0.236	0.764	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.236	0.764	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.236	0.764	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.236	0.764	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.236	0.764	0.000
C94.7 Other specified leukaemias	0.236	0.764	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.236	0.764	0.000
C94.5 Acute myelofibrosis	0.236	0.764	0.000
C94.4 Acute panmyelosis	0.236	0.764	0.000
C94.3 Mast cell leukaemia	0.236	0.764	0.000
C94.2 Acute megakaryoblastic leukaemia	0.236	0.764	0.000
C94.1 Chronic erythraemia	0.236	0.764	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.236	0.764	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.236	0.764	0.000
C96.8 Histiocytic sarcoma	0.236	0.764	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.236	0.764	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.236	0.764	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.236	0.764	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.236	0.764	0.000
C96.3 True histiocytic lymphoma	0.236	0.764	0.000
C96.2 Malignant mast cell tumour	0.236	0.764	0.000
C96.1 Malignant histiocytosis	0.236	0.764	0.000
C96.0 Letterer-Siwe disease	0.236	0.764	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.236	0.764	0.000
C92.9 Myeloid leukaemia, unspecified	0.233	0.767	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.233	0.767	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.233	0.767	0.000
C92.5 Acute myelomonocytic leukaemia	0.233	0.767	0.000
C92.3 Myeloid sarcoma	0.233	0.767	0.000
C92.2 Subacute myeloid leukaemia	0.233	0.767	0.000
C93.9 Monocytic leukaemia, unspecified	0.228	0.772	0.000
C93.7 Other monocytic leukaemia	0.228	0.772	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.228	0.772	0.000
C93.2 Subacute monocytic leukaemia	0.228	0.772	0.000
C93.0 Acute monocytic leukaemia	0.228	0.772	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.221	0.779	0.000
C85.1 B-cell lymphoma, unspecified	0.219	0.781	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.217	0.782	0.001
C93.1 Chronic monocytic leukaemia	0.217	0.783	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.211	0.789	0.000
C85.0 Lymphosarcoma	0.211	0.789	0.000
C83.3 Large cell (diffuse)	0.208	0.792	0.000
C92.4 Acute promyelocytic leukaemia	0.205	0.794	0.000
C92.1 Chronic myeloid leukaemia	0.163	0.837	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.156	0.844	0.001
C84.8 Cutaneous T-cell lymphoma, unspecified	0.156	0.844	0.001
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.156	0.844	0.001
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.156	0.844	0.001
C84.3 Lymphoepithelioid lymphoma	0.156	0.844	0.001
C84.2 T-zone lymphoma	0.156	0.844	0.001
C84.1 Sezary's diease	0.156	0.844	0.001
C84.0 Mycosis fungoides	0.156	0.844	0.001
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.147	0.853	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.135	0.864	0.000
C84.5 Other and unspecified T-cell lymphomas	0.132	0.868	0.001
C82.0 Small cleaved cell, follicular	0.111	0.889	0.000
C82.6 Cutaneous follicle centre lymphoma	0.097	0.902	0.000
C82.5 Diffuse follicle centre lymphoma	0.097	0.902	0.000
C82.4 Follicular lymphoma grade IIIb	0.097	0.902	0.000
C84.4 Peripheral T-cell lymphoma	0.092	0.907	0.001
C82.3 Follicular lymphoma grade IIIa	0.092	0.908	0.000
C82.2 Large cell, follicular	0.088	0.911	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.082	0.918	0.001
G20 Parkinson's disease	0.077	0.923	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.070	0.929	0.001
G20-G26 Extrapyramidal and movement disorders	0.053	0.947	0.000
G25 Other extrapyramidal and movement disorders	0.048	0.952	0.000
G25.0 Essential tremor	0.043	0.956	0.000
D86 Sarcoidosis	0.040	0.960	0.000
D80-D89 Certain disorders involving the immune mechanism	0.038	0.962	0.000
G23 Other degenerative diseases of basal ganglia	0.038	0.962	0.000
G21 Secondary Parkinsonism	0.038	0.962	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.038	0.962	0.000
G22 Parkinsonism in diseases classified elsewhere	0.038	0.962	0.000
G25.3 Myoclonus	0.038	0.962	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.038	0.962	0.000
D86.1 Sarcoidosis of lymph nodes	0.035	0.965	0.000
D86.8 Sarcoidosis of other and combined sites	0.035	0.965	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.035	0.965	0.000
D86.3 Sarcoidosis of skin	0.035	0.965	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.034	0.966	0.000
G25.5 Other chorea	0.034	0.966	0.000
G25.4 Drug-induced chorea	0.034	0.966	0.000
G25.1 Drug-induced tremor	0.034	0.966	0.000
G24 Dystonia	0.033	0.967	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.033	0.967	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.031	0.968	0.001
D80 Immunodeficiency with predominantly antibody defects	0.032	0.968	0.000
G25.2 Other specified forms of tremor	0.031	0.969	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.031	0.969	0.000
D86.9 Sarcoidosis, unspecified	0.031	0.969	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.030	0.970	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.030	0.970	0.000
D50-D53 Nutritional anaemias	0.030	0.970	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.029	0.971	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.029	0.971	0.000
D50 Iron deficiency anaemia	0.029	0.971	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.028	0.972	0.000
D55-D59 Haemolytic anaemias	0.028	0.972	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.028	0.972	0.000
D86.0 Sarcoidosis of lung	0.028	0.972	0.000
D82 Immunodeficiency associated with other major defects	0.028	0.972	0.000
D81 Combined immunodeficiencies	0.028	0.972	0.000
G21.9 Secondary Parkinsonism, unspecified	0.027	0.972	0.000
G21.8 Other secondary Parkinsonism	0.027	0.972	0.000
G21.4 Vascular parkinsonism	0.027	0.972	0.000
G21.3 Postencephalitic Parkinsonism	0.027	0.972	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.027	0.972	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.027	0.972	0.000
G21.0 Malignant neuroleptic syndrome	0.027	0.972	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.027	0.972	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.027	0.972	0.000
G23.3 Multiple system atrophy, cerebellar type	0.027	0.972	0.000
G23.2 Striatonigral degeneration	0.027	0.972	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.027	0.972	0.000
G23.0 Hallervorden-Spatz disease	0.027	0.972	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.027	0.973	0.000
D83 Common variable immunodeficiency	0.027	0.973	0.000
G24.5 Blepharospasm	0.027	0.973	0.000
D53 Other nutritional anaemias	0.026	0.974	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.026	0.974	0.000
D58 Other hereditary haemolytic anaemias	0.026	0.974	0.000
D89.3 Immune reconstitution syndrome	0.025	0.975	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.025	0.975	0.000
D89.1 Cryoglobulinaemia	0.025	0.975	0.000
D84 Other immunodeficiencies	0.025	0.975	0.000
D72 Other disorders of white blood cells	0.024	0.975	0.000
G24.4 Idiopathic orofacial dystonia	0.024	0.976	0.000
G24.2 Idiopathic nonfamilial dystonia	0.024	0.976	0.000
G24.1 Idiopathic familial dystonia	0.024	0.976	0.000
G24.0 Drug-induced dystonia	0.024	0.976	0.000
D68 Other coagulation defects	0.024	0.976	0.000
D69 Purpura and other haemorrhagic conditions	0.024	0.976	0.000
D72.8 Other specified disorders of white blood cells	0.023	0.977	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.977	0.023
G24.3 Spasmodic torticollis	0.023	0.977	0.000
G24.8 Other dystonia	0.023	0.977	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.023	0.977	0.000
D50.8 Other iron deficiency anaemias	0.023	0.977	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.023	0.977	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.023	0.977	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.023	0.977	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.023	0.977	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.023	0.977	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.023	0.977	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.023	0.977	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.023	0.977	0.000
D53.9 Nutritional anaemia, unspecified	0.023	0.977	0.000
D58.2 Other haemoglobinopathies	0.022	0.978	0.000
D69.0 Allergic purpura	0.022	0.978	0.000
D58.0 Hereditary spherocytosis	0.021	0.978	0.000
D68.8 Other specified coagulation defects	0.021	0.979	0.000
D68.6 Other Thrombophilia	0.021	0.979	0.000
D56 Thalassaemia	0.021	0.979	0.000
D50.1 Sideropenic dysphagia	0.021	0.979	0.000
D66 Hereditary factor VIII deficiency	0.021	0.979	0.000
D67 Hereditary factor IX deficiency	0.021	0.979	0.000
D57 Sickle-cell disorders	0.020	0.979	0.000
D55 Anaemia due to enzyme disorders	0.020	0.979	0.000
D81.9 Combined immunodeficiency, unspecified	0.020	0.980	0.000
D81.8 Other combined immunodeficiencies	0.020	0.980	0.000
D81.7 Major histocompatibility complex class II deficiency	0.020	0.980	0.000
D81.6 Major histocompatibility complex class I deficiency	0.020	0.980	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.020	0.980	0.000
D81.4 Nezelof's syndrome	0.020	0.980	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.020	0.980	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.020	0.980	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.020	0.980	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.020	0.980	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.020	0.980	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.020	0.980	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.020	0.980	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.020	0.980	0.000
D82.2 Immunodeficiency with short-limbed stature	0.020	0.980	0.000
D82.1 Di George's syndrome	0.020	0.980	0.000
D82.0 Wiskott-Aldrich syndrome	0.020	0.980	0.000
D69.2 Other nonthrombocytopenic purpura	0.020	0.980	0.000
D59 Acquired haemolytic anaemia	0.020	0.980	0.000
D69.4 Other primary thrombocytopenia	0.020	0.980	0.000
D83.8 Other common variable immunodeficiencies	0.019	0.981	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.019	0.981	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.019	0.981	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.019	0.981	0.000
N41.1 Chronic prostatitis	0.000	0.981	0.019
D72.1 Eosinophilia	0.019	0.981	0.000
D68.5 Primary Thrombophilia	0.019	0.981	0.000
D68.4 Acquired coagulation factor deficiency	0.019	0.981	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.019	0.981	0.000
D53.8 Other specified nutritional anaemias	0.019	0.981	0.000
D53.2 Scorbutic anaemia	0.019	0.981	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.019	0.981	0.000
D53.0 Protein deficiency anaemia	0.019	0.981	0.000
D74 Methaemoglobinaemia	0.019	0.981	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.019	0.981	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.019	0.981	0.000
D73 Diseases of spleen	0.019	0.981	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.018	0.981	0.000
D58.1 Hereditary elliptocytosis	0.018	0.981	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.019	0.981	0.000
D83.9 Common variable immunodeficiency, unspecified	0.018	0.981	0.000
D69.5 Secondary thrombocytopenia	0.018	0.982	0.000
G24.9 Dystonia, unspecified	0.018	0.982	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.018	0.982	0.000
D84.8 Other specified immunodeficiencies	0.018	0.982	0.000
D84.1 Defects in the complement system	0.018	0.982	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.018	0.982	0.000
D72.9 Disorder of white blood cells, unspecified	0.018	0.982	0.000
D72.0 Genetic anomalies of leukocytes	0.018	0.982	0.000
D68.1 Hereditary factor XI deficiency	0.018	0.982	0.000
D68.0 Von Willebrand's disease	0.018	0.982	0.000
D69.8 Other specified haemorrhagic conditions	0.017	0.983	0.000
D69.1 Qualitative platelet defects	0.017	0.983	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.017	0.983	0.000
D51 Vitamin B12 deficiency anaemia	0.017	0.983	0.000
D75 Other diseases of blood and blood-forming organs	0.017	0.983	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.017	0.983	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.017	0.983	0.000
D69.9 Haemorrhagic condition, unspecified	0.017	0.983	0.000
Chapter VI Diseases of the nervous system	0.017	0.983	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.017	0.983	0.000
D52 Folate deficiency anaemia	0.016	0.983	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.016	0.984	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.016	0.984	0.000
G50.0 Trigeminal neuralgia	0.016	0.984	0.000
K72.9 Hepatic failure, unspecified	0.016	0.984	0.000
G50 Disorders of trigeminal nerve	0.016	0.984	0.000
D56.3 Thalassaemia trait	0.015	0.985	0.000
D84.9 Immunodeficiency, unspecified	0.015	0.985	0.000
D56.9 Thalassaemia, unspecified	0.015	0.985	0.000
D56.8 Other thalassaemias	0.015	0.985	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.015	0.985	0.000
D56.2 Delta-beta thalassaemia	0.015	0.985	0.000
D56.1 Beta thalassaemia	0.015	0.985	0.000
D56.0 Alpha thalassaemia	0.015	0.985	0.000
G54 Nerve root and plexus disorders	0.015	0.985	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.015	0.985	0.000
D55.8 Other anaemias due to enzyme disorders	0.015	0.985	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.015	0.985	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.015	0.985	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.015	0.985	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.015	0.985	0.000
D57.8 Other sickle-cell disorders	0.015	0.985	0.000
D57.3 Sickle-cell trait	0.015	0.985	0.000
D57.2 Double heterozygous sickling disorders	0.015	0.985	0.000
D57.1 Sickle-cell anaemia without crisis	0.015	0.985	0.000
D57.0 Sickle-cell anaemia with crisis	0.015	0.985	0.000
D73.8 Other diseases of spleen	0.015	0.985	0.000
G06.2 Extradural and subdural abscess, unspecified	0.015	0.985	0.000
D73.1 Hypersplenism	0.015	0.985	0.000
D73.3 Abscess of spleen	0.015	0.985	0.000
D50.9 Iron deficiency anaemia, unspecified	0.015	0.985	0.000
D59.8 Other acquired haemolytic anaemias	0.014	0.985	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.014	0.985	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.014	0.985	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.014	0.985	0.000
D59.3 Haemolytic-uraemic syndrome	0.014	0.985	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.014	0.985	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.014	0.985	0.000
G06.1 Intraspinal abscess and granuloma	0.014	0.985	0.000
G51 Facial nerve disorders	0.015	0.985	0.000
D60-D64 Aplastic and other anaemias	0.015	0.985	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.014	0.986	0.000
R20.2 Paraesthesia of skin	0.014	0.986	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.014	0.986	0.000
D68.9 Coagulation defect, unspecified	0.014	0.986	0.000
G30-G32 Other degenerative diseases of the nervous system	0.014	0.986	0.000
G58 Other mononeuropathies	0.014	0.986	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.014	0.986	0.000
D74.9 Methaemoglobinaemia, unspecified	0.013	0.986	0.000
D74.8 Other methaemoglobinaemias	0.013	0.986	0.000
D74.0 Congenital methaemoglobinaemia	0.013	0.986	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.014	0.986	0.000
D73.9 Disease of spleen, unspecified	0.014	0.986	0.000
D73.2 Chronic congestive splenomegaly	0.014	0.986	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.013	0.986	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.013	0.986	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.013	0.986	0.000
G03 Meningitis due to other and unspecified causes	0.014	0.986	0.000
D73.4 Cyst of spleen	0.013	0.986	0.000
D76.3 Other histiocytosis syndromes	0.013	0.986	0.000
G54.0 Brachial plexus disorders	0.013	0.987	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.013	0.987	0.000
G00 Bacterial meningitis, not elsewhere classified	0.013	0.987	0.000
D75.2 Essential thrombocytosis	0.013	0.987	0.000
G58.9 Mononeuropathy, unspecified	0.013	0.987	0.000
K72 Hepatic failure, not elsewhere classified	0.013	0.987	0.000
G54.6 Phantom limb syndrome with pain	0.013	0.987	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.012	0.987	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.012	0.987	0.000
D51.2 Transcobalamin II deficiency	0.012	0.987	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.012	0.987	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.012	0.987	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.012	0.987	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.012	0.988	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.012	0.988	0.000
G30 Alzheimer's disease	0.012	0.988	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.012	0.988	0.000
D52.8 Other folate deficiency anaemias	0.012	0.988	0.000
D52.1 Drug-induced folate deficiency anaemia	0.012	0.988	0.000
D52.0 Dietary folate deficiency anaemia	0.012	0.988	0.000
G51.3 Clonic hemifacial spasm	0.012	0.988	0.000
D73.0 Hyposplenism	0.012	0.988	0.000
G61 Inflammatory polyneuropathy	0.012	0.988	0.000
G51.9 Disorder of facial nerve, unspecified	0.012	0.988	0.000
N41 Inflammatory diseases of prostate	0.000	0.988	0.012
G53 Cranial nerve disorders in diseases classified elsewhere	0.012	0.988	0.000
G58.7 Mononeuritis multiplex	0.012	0.988	0.000
D62 Acute posthaemorrhagic anaemia	0.012	0.988	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.012	0.988	0.000
D75.0 Familial erythrocytosis	0.011	0.988	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.011	0.988	0.000
G50.8 Other disorders of trigeminal nerve	0.011	0.988	0.000
G54.8 Other nerve root and plexus disorders	0.011	0.989	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.011	0.989	0.000
G52 Disorders of other cranial nerves	0.011	0.989	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.011	0.989	0.000
G61.0 Guillain-Barre syndrome	0.011	0.989	0.000
G70-G73 Diseases of myoneural junction and muscle	0.011	0.989	0.000
G03.9 Meningitis, unspecified	0.011	0.989	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.989	0.011
G54.7 Phantom limb syndrome without pain	0.011	0.989	0.000
G54.5 Neuralgic amyotrophy	0.011	0.989	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.011	0.989	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.011	0.989	0.000
G54.1 Lumbosacral plexus disorders	0.011	0.989	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.011	0.989	0.000
G51.0 Bell's palsy	0.011	0.989	0.000
G51.8 Other disorders of facial nerve	0.011	0.989	0.000
K72.0 Acute and subacute hepatic failure	0.011	0.989	0.000
G51.4 Facial myokymia	0.011	0.989	0.000
G51.2 Melkersson's syndrome	0.011	0.989	0.000
G51.1 Geniculate ganglionitis	0.011	0.989	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.011	0.989	0.000
G50.1 Atypical facial pain	0.010	0.989	0.000
G00.9 Bacterial meningitis, unspecified	0.010	0.989	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.010	0.990	0.000
K72.1 Chronic hepatic failure	0.010	0.990	0.000
D70 Agranulocytosis	0.010	0.990	0.000
G58.0 Intercostal neuropathy	0.010	0.990	0.000
D73.5 Infarction of spleen	0.010	0.990	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.010	0.990	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.010	0.990	0.000
G30.1 Alzheimer's disease with late onset	0.010	0.990	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.010	0.990	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.010	0.990	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.010	0.990	0.000
G30.8 Other Alzheimer's disease	0.010	0.990	0.000
G30.9 Alzheimer's disease, unspecified	0.010	0.990	0.000
G03.8 Meningitis due to other specified causes	0.010	0.990	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.010	0.990	0.000
G03.1 Chronic meningitis	0.010	0.990	0.000
G03.0 Nonpyogenic meningitis	0.010	0.990	0.000
G61.8 Other inflammatory polyneuropathies	0.010	0.990	0.000
G00.1 Pneumococcal meningitis	0.010	0.990	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.010	0.990	0.000
G04.1 Tropical spastic paraplegia	0.010	0.990	0.000
G04.0 Acute disseminated encephalitis	0.010	0.990	0.000
G00.8 Other bacterial meningitis	0.010	0.990	0.000
G00.3 Staphylococcal meningitis	0.010	0.990	0.000
G00.2 Streptococcal meningitis	0.010	0.990	0.000
G00.0 Haemophilus meningitis	0.010	0.990	0.000
K75.8 Other specified inflammatory liver diseases	0.010	0.990	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.010	0.990	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.009	0.990	0.000
G59.0 Diabetic mononeuropathy	0.010	0.990	0.000
G60 Hereditary and idiopathic neuropathy	0.009	0.990	0.000
G06.0 Intracranial abscess and granuloma	0.009	0.991	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.009	0.991	0.000
D68.2 Hereditary deficiency of other clotting factors	0.009	0.991	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
G02.1 Meningitis in mycoses	0.009	0.991	0.000
L40.5 Arthropathic psoriasis	0.009	0.991	0.000
G64 Other disorders of peripheral nervous system	0.009	0.991	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.009	0.991	0.000
G14 Postpolio syndrome	0.009	0.991	0.000
K70-K77 Diseases of liver	0.009	0.991	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.009	0.991	0.000
D61 Other aplastic anaemias	0.009	0.991	0.000
G61.1 Serum neuropathy	0.009	0.991	0.000
N41.3 Prostatocystitis	0.000	0.991	0.009
N41.2 Abscess of prostate	0.000	0.991	0.009
G61.9 Inflammatory polyneuropathy, unspecified	0.009	0.991	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.009	0.991	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.009	0.991	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.009	0.991	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
K70 Alcoholic liver disease	0.009	0.991	0.000
D59.1 Other autoimmune haemolytic anaemias	0.008	0.991	0.001
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.009	0.991	0.000
G53.0 Postzoster neuralgia	0.009	0.991	0.000
G72 Other myopathies	0.009	0.991	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.991	0.008
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.008	0.991	0.000
G10 Huntington's disease	0.008	0.991	0.000
N41.0 Acute prostatitis	0.000	0.991	0.008
G52.8 Disorders of other specified cranial nerves	0.008	0.992	0.000
G52.7 Disorders of multiple cranial nerves	0.008	0.992	0.000
G52.3 Disorders of hypoglossal nerve	0.008	0.992	0.000
G52.2 Disorders of vagus nerve	0.008	0.992	0.000
G52.1 Disorders of glossopharyngeal nerve	0.008	0.992	0.000
G52.0 Disorders of olfactory nerve	0.008	0.992	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.008	0.992	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.008	0.992	0.000
G30.0 Alzheimer's disease with early onset	0.008	0.992	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.008	0.992	0.000
D69.6 Thrombocytopenia, unspecified	0.008	0.992	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.008	0.992	0.000
G11 Hereditary ataxia	0.008	0.992	0.000
K70.9 Alcoholic liver disease, unspecified	0.008	0.992	0.000
K70.3 Alcoholic cirrhosis of liver	0.008	0.992	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.008	0.992	0.000
D60.8 Other acquired pure red cell aplasias	0.008	0.992	0.000
D60.1 Transient acquired pure red cell aplasia	0.008	0.992	0.000
D60.0 Chronic acquired pure red cell aplasia	0.008	0.992	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.008	0.992	0.000
G52.9 Cranial nerve disorder, unspecified	0.007	0.992	0.000
E11.6 With other specified complications	0.008	0.992	0.000
G70 Myasthenia gravis and other myoneural disorders	0.008	0.992	0.000
E11.2 With renal complications	0.008	0.992	0.000
G57 Mononeuropathies of lower limb	0.008	0.992	0.000
S92.30 Fracture of metatarsal bone (closed)	0.008	0.992	0.000
G31.8 Other specified degenerative diseases of nervous system	0.007	0.992	0.000
K75 Other inflammatory liver diseases	0.007	0.992	0.000
G71 Primary disorders of muscles	0.007	0.993	0.000
G12 Spinal muscular atrophy and related syndromes	0.007	0.993	0.000
W22.9 Unspecified place	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.007	0.993	0.001
D52.9 Folate deficiency anaemia, unspecified	0.007	0.993	0.000
E11 Non-insulin-dependent diabetes mellitus	0.007	0.993	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.007	0.993	0.000
G60.3 Idiopathic progressive neuropathy	0.007	0.993	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.007	0.993	0.000
G60.1 Refsum's disease	0.007	0.993	0.000
G90-G99 Other disorders of the nervous system	0.007	0.993	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.007	0.993	0.000
K70.4 Alcoholic hepatic failure	0.007	0.993	0.000
L40 Psoriasis	0.007	0.993	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.007	0.993	0.000
D61.1 Drug-induced aplastic anaemia	0.007	0.993	0.000
G31.0 Circumscribed brain atrophy	0.007	0.993	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations