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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74241297
log Bayes Factor = 35.7526
Chromosome 13   position 27,525,516  (GRCh37) Explore rs74241297 on Ensembl!
Variant rs74241297 is part of Cluster X0205

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
R10 Abdominal and pelvic pain
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.996 0.004 0.000
J44 Other chronic obstructive pulmonary disease
0.996 0.004 0.000
R10.1 Pain localised to upper abdomen
0.994 0.006 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.992 0.008 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.992 0.008 0.000
Z13 Special screening examination for other diseases and disorders
0.990 0.010 0.000
H40-H42 Glaucoma
0.990 0.010 0.000
T81 Complications of procedures, not elsewhere classified
0.989 0.011 0.000
Z13.9 Special screening examination, unspecified
0.989 0.011 0.000
J30-J39 Other diseases of upper respiratory tract
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
H40 Glaucoma
0.983 0.017 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.981 0.019 0.000
C15-C26 Malignant neoplasms of digestive organs
0.980 0.020 0.000
Z98 Other postsurgical states
0.977 0.023 0.000
Z86 Personal history of certain other diseases
0.976 0.024 0.000
M15-M19 Arthrosis
0.976 0.024 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.975 0.025 0.000
M19 Other arthrosis
0.973 0.027 0.000
D10-D36 Benign neoplasms
0.972 0.028 0.000
H04 Disorders of lachrymal system
0.972 0.028 0.000
M19.9 Arthrosis, unspecified
0.970 0.030 0.000
Z86.7 Personal history of diseases of the circulatory system
0.969 0.031 0.000
Chapter VIII Diseases of the ear and mastoid process
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.968 0.032 0.000
R50-R69 General symptoms and signs
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.967 0.033 0.000
N20-N23 Urolithiasis
0.963 0.037 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.960 0.040 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.959 0.041 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.957 0.043 0.000
C20 Malignant neoplasm of rectum
0.957 0.043 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.954 0.046 0.000
K50-K52 Noninfective enteritis and colitis
0.953 0.047 0.000
Chapter I Certain infectious and parasitic diseases
0.950 0.050 0.000
N20 Calculus of kidney and ureter
0.949 0.051 0.000
L60-L75 Disorders of skin appendages
0.948 0.052 0.000
Chapter IX Diseases of the circulatory system
0.948 0.052 0.000
J47 Bronchiectasis
0.947 0.053 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.945 0.055 0.000
J33 Nasal polyp
0.944 0.056 0.000
R11 Nausea and vomiting
0.942 0.058 0.000
Z98.0 Intestinal bypass and anastomosis status
0.941 0.059 0.000
D12.8 Rectum
0.940 0.060 0.000
M13 Other arthritis
0.938 0.062 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.935 0.065 0.000
B95-B98 Bacterial, viral and other infectious agents
0.935 0.065 0.000
H65-H75 Diseases of middle ear and mastoid
0.935 0.065 0.000
I30-I52 Other forms of heart disease
0.935 0.065 0.000
Z95.0 Presence of cardiac pacemaker
0.934 0.066 0.000
R55 Syncope and collapse
0.933 0.067 0.000
N60-N64 Disorders of breast
0.928 0.072 0.000
M45-M49 Spondylopathies
0.926 0.074 0.000
N20.1 Calculus of ureter
0.925 0.075 0.000
H40.1 Primary open-angle glaucoma
0.924 0.076 0.000
R10.4 Other and unspecified abdominal pain
0.922 0.078 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.921 0.079 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.917 0.083 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.916 0.084 0.000
M13.9 Arthritis, unspecified
0.916 0.084 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.915 0.085 0.000
L72.1 Trichilemmal cyst
0.913 0.087 0.000
K80 Cholelithiasis
0.913 0.087 0.000
Chapter XX External causes of morbidity and mortality
0.912 0.088 0.000
Z93 Artificial opening status
0.911 0.089 0.000
H02 Other disorders of eyelid
0.910 0.090 0.000
R06 Abnormalities of breathing
0.909 0.091 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.907 0.093 0.000
H40.0 Glaucoma suspect
0.907 0.093 0.000
Chapter V Mental and behavioural disorders
0.907 0.093 0.000
J95-J99 Other diseases of the respiratory system
0.904 0.096 0.000
M19.94 Arthrosis, unspecified (Hand)
0.904 0.096 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.903 0.097 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.900 0.100 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.900 0.100 0.000
H53-H54 Visual disturbances and blindness
0.900 0.100 0.000
S80-S89 Injuries to the knee and lower leg
0.898 0.102 0.000
K55-K64 Other diseases of intestines
0.897 0.103 0.000
K51 Ulcerative colitis
0.893 0.107 0.000
Z83 Family history of other specific disorders
0.893 0.107 0.000
G40-G47 Episodic and paroxysmal disorders
0.893 0.107 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.884 0.116 0.000
L40-L45 Papulosquamous disorders
0.881 0.119 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.881 0.119 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.879 0.121 0.000
K70-K77 Diseases of liver
0.879 0.121 0.000
S01 Open wound of head
0.879 0.121 0.000
R63 Symptoms and signs concerning food and fluid intake
0.875 0.125 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.875 0.125 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.874 0.126 0.000
Z95.1 Presence of aortocoronary bypass graft
0.872 0.128 0.000
J32 Chronic sinusitis
0.868 0.132 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.868 0.132 0.000
Z12 Special screening examination for neoplasms
0.867 0.133 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.866 0.134 0.000
H02.4 Ptosis of eyelid
0.865 0.135 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.865 0.135 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.863 0.137 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.862 0.138 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.860 0.140 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.858 0.142 0.000
H72 Perforation of tympanic membrane
0.857 0.143 0.000
G40 Epilepsy
0.854 0.146 0.000
H40.9 Glaucoma, unspecified
0.854 0.146 0.000
D23 Other benign neoplasms of skin
0.853 0.147 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.853 0.147 0.000
J33.0 Polyp of nasal cavity
0.849 0.151 0.000
N20.0 Calculus of kidney
0.848 0.152 0.000
R06.5 Mouth breathing
0.846 0.154 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.845 0.155 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.841 0.158 0.000
F30-F39 Mood [affective] disorders
0.841 0.159 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.841 0.159 0.000
Z83.5 Family history of eye and ear disorders
0.841 0.159 0.000
N99-N99 Other disorders of the genitourinary system
0.840 0.160 0.000
S00 Superficial injury of head
0.838 0.162 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.837 0.163 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.837 0.163 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.834 0.166 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.833 0.167 0.000
H04.2 Epiphora
0.833 0.167 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.832 0.168 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.832 0.168 0.000
N10-N16 Renal tubulo-interstitial diseases
0.832 0.168 0.000
K61 Abscess of anal and rectal regions
0.831 0.169 0.000
I60-I69 Cerebrovascular diseases
0.831 0.169 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.831 0.169 0.000
S40-S49 Injuries to the shoulder and upper arm
0.830 0.169 0.000
I47 Paroxysmal tachycardia
0.830 0.170 0.000
S02 Fracture of skull and facial bones
0.829 0.170 0.000
Z89 Acquired absence of limb
0.828 0.172 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.827 0.173 0.000
K04 Diseases of pulp and periapical tissues
0.825 0.175 0.000
J33.8 Other polyp of sinus
0.823 0.177 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.823 0.177 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.822 0.178 0.000
R07 Pain in throat and chest
0.822 0.178 0.000
G40.9 Epilepsy, unspecified
0.822 0.178 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.820 0.180 0.000
D13.1 Stomach
0.820 0.180 0.000
H54 Blindness and low vision
0.819 0.181 0.000
N60 Benign mammary dysplasia
0.819 0.181 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.819 0.181 0.000
H66 Suppurative and unspecified otitis media
0.818 0.182 0.000
R05 Cough
0.817 0.183 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.814 0.186 0.000
S80 Superficial injury of lower leg
0.813 0.187 0.000
J98 Other respiratory disorders
0.812 0.188 0.000
N30-N39 Other diseases of urinary system
0.812 0.188 0.000
J20-J22 Other acute lower respiratory infections
0.809 0.191 0.000
H60-H62 Diseases of external ear
0.809 0.191 0.000
M47 Spondylosis
0.808 0.192 0.000
D32 Benign neoplasm of meninges
0.807 0.193 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.807 0.193 0.000
Z92 Personal history of medical treatment
0.807 0.193 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.806 0.194 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.806 0.194 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.806 0.194 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.806 0.194 0.000
R18 Ascites
0.805 0.195 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.805 0.195 0.000
Z98.8 Other specified postsurgical states
0.804 0.196 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.803 0.197 0.000
L40 Psoriasis
0.803 0.197 0.000
R07.3 Other chest pain
0.803 0.197 0.000
K52 Other non-infective gastro-enteritis and colitis
0.801 0.199 0.000
K80.4 Calculus of bile duct with cholecystitis
0.800 0.200 0.000
R53 Malaise and fatigue
0.799 0.201 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.799 0.201 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.799 0.201 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.798 0.202 0.000
E70-E90 Metabolic disorders
0.797 0.203 0.000
T42.4 Benzodiazepines
0.797 0.203 0.000
S06 Intracranial injury
0.796 0.204 0.000
N80 Endometriosis
0.796 0.204 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.795 0.205 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.795 0.205 0.000
H25-H28 Disorders of lens
0.794 0.206 0.000
I50 Heart failure
0.794 0.206 0.000
M20-M25 Other joint disorders
0.794 0.206 0.000
Z81 Family history of mental and behavioural disorders
0.793 0.207 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.793 0.207 0.000
K63 Other diseases of intestine
0.791 0.209 0.000
R52 Pain, not elsewhere classified
0.791 0.209 0.000
M50-M54 Other dorsopathies
0.791 0.209 0.000
K86 Other diseases of pancreas
0.790 0.210 0.000
R47-R49 Symptoms and signs involving speech and voice
0.789 0.210 0.000
I42 Cardiomyopathy
0.789 0.211 0.000
C18 Malignant neoplasm of colon
0.789 0.211 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.787 0.212 0.000
H40.2 Primary angle-closure glaucoma
0.786 0.214 0.000
N00-N08 Glomerular diseases
0.785 0.215 0.000
I49 Other cardiac arrhythmias
0.785 0.215 0.000
K70 Alcoholic liver disease
0.784 0.216 0.000
K61.0 Anal abscess
0.784 0.216 0.000
K02 Dental caries
0.784 0.216 0.000
N40-N51 Diseases of male genital organs
0.783 0.217 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.782 0.217 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.782 0.218 0.000
S60-S69 Injuries to the wrist and hand
0.782 0.218 0.000
Z86.0 Personal history of other neoplasms
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.780 0.220 0.000
F32 Depressive episode
0.780 0.220 0.000
D12.3 Transverse colon
0.778 0.222 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.778 0.222 0.000
Z97 Presence of other devices
0.778 0.222 0.000
M48 Other spondylopathies
0.777 0.223 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
Chapter XXII Codes for special purposes
0.777 0.223 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.776 0.224 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.775 0.225 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.774 0.226 0.000
J31.0 Chronic rhinitis
0.774 0.226 0.000
M10 Gout
0.773 0.227 0.000
M60-M63 Disorders of muscles
0.773 0.227 0.000
H65 Nonsuppurative otitis media
0.771 0.228 0.000
D12.6 Colon, unspecified
0.771 0.229 0.000
Z98.1 Arthrodesis status
0.770 0.230 0.000
J43 Emphysema
0.770 0.230 0.000
N17-N19 Renal failure
0.770 0.230 0.000
D12.5 Sigmoid colon
0.768 0.232 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.768 0.232 0.000
R61 Hyperhidrosis
0.765 0.235 0.000
K55 Vascular disorders of intestine
0.765 0.235 0.000
M13.94 Arthritis, unspecified (Hand)
0.765 0.235 0.000
K63.8 Other specified diseases of intestine
0.765 0.235 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.764 0.235 0.000
T43.2 Other and unspecified antidepressants
0.764 0.236 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.764 0.236 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.763 0.237 0.000
C80 Malignant neoplasm without specification of site
0.763 0.237 0.000
Z95.4 Presence of other heart-valve replacement
0.761 0.239 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.761 0.239 0.000
R10.3 Pain localised to other parts of lower abdomen
0.761 0.239 0.000
H04.1 Other disorders of lachrymal gland
0.761 0.239 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.761 0.239 0.000
M80-M85 Disorders of bone density and structure
0.759 0.241 0.000
N63 Unspecified lump in breast
0.759 0.241 0.000
R63.4 Abnormal weight loss
0.757 0.243 0.000
R06.0 Dyspnoea
0.757 0.243 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.757 0.243 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.757 0.243 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
Z93.5 Cystostomy status
0.753 0.247 0.000
G20-G26 Extrapyramidal and movement disorders
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.752 0.248 0.000
N80.9 Endometriosis, unspecified
0.751 0.249 0.000
J33.9 Nasal polyp, unspecified
0.750 0.250 0.000
K83 Other diseases of biliary tract
0.749 0.251 0.000
T90 Sequelae of injuries of head
0.748 0.252 0.000
L57.0 Actinic keratosis
0.748 0.252 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.747 0.253 0.000
H00 Hordeolum and chalazion
0.747 0.253 0.000
N32 Other disorders of bladder
0.747 0.253 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.747 0.253 0.000
L40.9 Psoriasis, unspecified
0.746 0.254 0.000
K11 Diseases of salivary glands
0.746 0.254 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.746 0.254 0.000
J98.4 Other disorders of lung
0.746 0.254 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.745 0.254 0.000
G30-G32 Other degenerative diseases of the nervous system
0.745 0.255 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.745 0.255 0.000
Z93.2 Ileostomy status
0.744 0.256 0.000
J30 Vasomotor and allergic rhinitis
0.744 0.256 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.743 0.257 0.000
I35 Nonrheumatic aortic valve disorders
0.743 0.257 0.000
I69 Sequelae of cerebrovascular disease
0.742 0.258 0.000
R54 Senility
0.741 0.259 0.000
M11 Other crystal arthropathies
0.741 0.259 0.000
J40 Bronchitis, not specified as acute or chronic
0.741 0.259 0.000
Z93.1 Gastrostomy status
0.740 0.260 0.000
R30-R39 Symptoms and signs involving the urinary system
0.740 0.260 0.000
M25 Other joint disorders, not elsewhere classified
0.740 0.260 0.000
M65-M68 Disorders of synovium and tendon
0.739 0.260 0.000
E87.5 Hyperkalaemia
0.739 0.261 0.000
K51.2 Ulcerative (chronic) proctitis
0.739 0.261 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.739 0.261 0.000
I31 Other diseases of pericardium
0.739 0.261 0.000
K51.9 Ulcerative colitis, unspecified
0.738 0.262 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.737 0.263 0.000
I51 Complications and ill-defined descriptions of heart disease
0.736 0.264 0.000
K65-K67 Diseases of peritoneum
0.736 0.264 0.000
Z72 Problems related to lifestyle
0.736 0.264 0.000
S80.9 Superficial injury of lower leg, unspecified
0.735 0.265 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.735 0.265 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.735 0.265 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.734 0.266 0.000
M40-M43 Deforming dorsopathies
0.734 0.266 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.734 0.266 0.000
M47.8 Other spondylosis
0.733 0.267 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.733 0.267 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.733 0.267 0.000
C16 Malignant neoplasm of stomach
0.732 0.267 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
C78.7 Secondary malignant neoplasm of liver
0.731 0.269 0.000
R59 Enlarged lymph nodes
0.731 0.269 0.000
N25-N29 Other disorders of kidney and ureter
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
Z43 Attention to artificial openings
0.730 0.270 0.000
R25 Abnormal involuntary movements
0.730 0.270 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.730 0.270 0.000
Z60 Problems related to social environment
0.730 0.270 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.729 0.270 0.000
T85.2 Mechanical complication of intraocular lens
0.729 0.271 0.000
F32.9 Depressive episode, unspecified
0.727 0.273 0.000
Z91.6 Personal history of other physical trauma
0.727 0.273 0.000
K08 Other disorders of teeth and supporting structures
0.727 0.273 0.000
M19.0 Primary arthrosis of other joints
0.726 0.274 0.000
I05-I09 Chronic rheumatic heart diseases
0.726 0.274 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.726 0.274 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.726 0.274 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.725 0.275 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.724 0.276 0.000
H90-H95 Other disorders of ear
0.724 0.276 0.000
S01.9 Open wound of head, part unspecified
0.722 0.278 0.000
M46 Other inflammatory spondylopathies
0.722 0.278 0.000
D12.7 Rectosigmoid junction
0.720 0.280 0.000
R01 Cardiac murmurs and other cardiac sounds
0.720 0.280 0.000
H52 Disorders of refraction and accommodation
0.720 0.280 0.000
H72.0 Central perforation of tympanic membrane
0.720 0.280 0.000
D23.4 Skin of scalp and neck
0.720 0.280 0.000
I60 Subarachnoid haemorrhage
0.719 0.281 0.000
K04.5 Chronic apical periodontitis
0.719 0.281 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.718 0.282 0.000
H43-H45 Disorders of vitreous body and globe
0.718 0.282 0.000
L73 Other follicular disorders
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.717 0.283 0.000
H10-H13 Disorders of conjunctiva
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
J46 Status asthmaticus
0.716 0.284 0.000
J42 Unspecified chronic bronchitis
0.716 0.284 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.716 0.284 0.000
M70-M79 Other soft tissue disorders
0.716 0.284 0.000
J32.0 Chronic maxillary sinusitis
0.715 0.285 0.000
R10.0 Acute abdomen
0.715 0.285 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
L50-L54 Urticaria and erythema
0.715 0.285 0.000
N62 Hypertrophy of breast
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.715 0.285 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.714 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.714 0.286 0.000
R29.6 Tendency to fall, not elsewhere classified
0.714 0.286 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.713 0.287 0.000
S01.8 Open wound of other parts of head
0.713 0.287 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.713 0.287 0.000
L71 Rosacea
0.713 0.287 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.713 0.287 0.000
K76 Other diseases of liver
0.713 0.287 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.713 0.287 0.000
G90-G99 Other disorders of the nervous system
0.712 0.287 0.000
H54.9 Unspecified visual impairment (binocular)
0.712 0.288 0.000
H02.8 Other specified disorders of eyelid
0.711 0.289 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.711 0.289 0.000
H05 Disorders of orbit
0.711 0.289 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.711 0.289 0.000
N13 Obstructive and reflux uropathy
0.711 0.289 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.710 0.290 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.710 0.290 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.710 0.290 0.000
R56 Convulsions, not elsewhere classified
0.710 0.290 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.710 0.290 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.710 0.290 0.000
Z13.5 Special screening examination for eye and ear disorders
0.710 0.290 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.710 0.290 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.710 0.290 0.000
Z13.2 Special screening examination for nutritional disorders
0.710 0.290 0.000
Z13.1 Special screening examination for diabetes mellitus
0.710 0.290 0.000
H42 Glaucoma in diseases classified elsewhere
0.710 0.290 0.000
J32.8 Other chronic sinusitis
0.709 0.290 0.000
T81.9 Unspecified complication of procedure
0.709 0.291 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.709 0.291 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.709 0.291 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.709 0.291 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.709 0.291 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.709 0.291 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.708 0.291 0.000
J37 Chronic laryngitis and laryngotracheitis
0.708 0.291 0.000
N80.1 Endometriosis of ovary
0.708 0.291 0.000
C77.9 Lymph node, unspecified
0.708 0.292 0.000
R21 Rash and other nonspecific skin eruption
0.707 0.293 0.000
R02 Gangrene, not elsewhere classified
0.707 0.293 0.000
Z93.3 Colostomy status
0.707 0.293 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.706 0.294 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.705 0.295 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.705 0.295 0.000
Z89.4 Acquired absence of foot and ankle
0.705 0.295 0.000
H40.8 Other glaucoma
0.704 0.295 0.000
H40.6 Glaucoma secondary to drugs
0.704 0.295 0.000
H40.5 Glaucoma secondary to other eye disorders
0.704 0.295 0.000
H40.4 Glaucoma secondary to eye inflammation
0.704 0.295 0.000
H40.3 Glaucoma secondary to eye trauma
0.704 0.295 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.704 0.296 0.000
K81 Cholecystitis
0.704 0.296 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.703 0.296 0.000
M35 Other systemic involvement of connective tissue
0.703 0.297 0.000
R06.2 Wheezing
0.703 0.297 0.000
Z95.3 Presence of xenogenic heart valve
0.703 0.297 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.703 0.297 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.703 0.297 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.702 0.297 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.702 0.297 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.702 0.297 0.000
C21 Malignant neoplasm of anus and anal canal
0.702 0.297 0.000
C17 Malignant neoplasm of small intestine
0.702 0.297 0.000
C23 Malignant neoplasm of gallbladder
0.702 0.297 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.702 0.298 0.000
I50.9 Heart failure, unspecified
0.702 0.298 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.701 0.299 0.000
C25 Malignant neoplasm of pancreas
0.701 0.299 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.700 0.300 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.700 0.300 0.000
M15 Polyarthrosis
0.700 0.300 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.699 0.301 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.699 0.301 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.699 0.301 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.699 0.301 0.000
T36 Poisoning by systemic antibiotics
0.699 0.301 0.000
R10.2 Pelvic and perineal pain
0.698 0.302 0.000
I38 Endocarditis, valve unspecified
0.698 0.302 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.698 0.302 0.000
H66.3 Other chronic suppurative otitis media
0.698 0.302 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
M19.8 Other specified arthrosis
0.697 0.303 0.000
M19.2 Other secondary arthrosis
0.697 0.303 0.000
M19.1 Posttraumatic arthrosis of other joints
0.697 0.303 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.697 0.303 0.000
K50 Crohn's disease [regional enteritis]
0.697 0.303 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.697 0.303 0.000
D31 Benign neoplasm of eye and adnexa
0.697 0.303 0.000
D30 Benign neoplasm of urinary organs
0.697 0.303 0.000
D29 Benign neoplasm of male genital organs
0.697 0.303 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.697 0.303 0.000
D26 Other benign neoplasms of uterus
0.697 0.303 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.697 0.303 0.000
D19 Benign neoplasm of mesothelial tissue
0.697 0.303 0.000
D16 Benign neoplasm of bone and articular cartilage
0.697 0.303 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.697 0.303 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.697 0.303 0.000
D10 Benign neoplasm of mouth and pharynx
0.697 0.303 0.000
D34 Benign neoplasm of thyroid gland
0.697 0.303 0.000
S42 Fracture of shoulder and upper arm
0.697 0.303 0.000
H04.9 Disorder of lachrymal system, unspecified
0.697 0.303 0.000
H04.8 Other disorders of lachrymal system
0.697 0.303 0.000
H04.6 Other changes in lachrymal passages
0.697 0.303 0.000
H04.4 Chronic inflammation of lachrymal passages
0.697 0.303 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.697 0.303 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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