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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74290525
log Bayes Factor = 4.51488
Chromosome 6   position 31,835,162  (GRCh37) Explore rs74290525 on Ensembl!
Variant rs74290525 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.074 0.926
E00-E07 Disorders of thyroid gland
0.000 0.126 0.874
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.149 0.851
E10-E14 Diabetes mellitus
0.000 0.159 0.841
E11 Non-insulin-dependent diabetes mellitus
0.000 0.166 0.834
E11.9 Without complications
0.000 0.166 0.834
E65-E68 Obesity and other hyperalimentation
0.000 0.204 0.796
E66 Obesity
0.000 0.244 0.756
E14 Unspecified diabetes mellitus
0.000 0.272 0.728
E66.9 Obesity, unspecified
0.000 0.299 0.701
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.302 0.698
E03.8 Other specified hypothyroidism
0.000 0.336 0.664
E03.5 Myxoedema coma
0.000 0.336 0.664
E03.4 Atrophy of thyroid (acquired)
0.000 0.336 0.664
E03.3 Postinfectious hypothyroidism
0.000 0.336 0.664
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.336 0.664
E03.1 Congenital hypothyroidism without goitre
0.000 0.336 0.664
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.336 0.664
E14.9 Without complications
0.000 0.357 0.643
E66.8 Other obesity
0.000 0.357 0.643
E11.2 With renal complications
0.000 0.364 0.636
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.373 0.626
E00 Congenital iodine-deficiency syndrome
0.000 0.373 0.626
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.373 0.626
E06 Thyroiditis
0.000 0.374 0.626
E50-E64 Other nutritional deficiencies
0.000 0.374 0.626
E13 Other specified diabetes mellitus
0.000 0.397 0.603
E12 Malnutrition-related diabetes mellitus
0.000 0.397 0.603
E11.8 With unspecified complications
0.000 0.402 0.598
E11.7 With multiple complications
0.000 0.402 0.598
E11.6 With other specified complications
0.000 0.402 0.598
E11.0 With coma
0.000 0.402 0.598
E07 Other disorders of thyroid
0.000 0.405 0.595
E40-E46 Malnutrition
0.000 0.413 0.587
E11.5 With peripheral circulatory complications
0.000 0.416 0.583
E05.9 Thyrotoxicosis, unspecified
0.000 0.419 0.581
E20-E35 Disorders of other endocrine glands
0.000 0.428 0.572
E67 Other hyperalimentation
0.000 0.429 0.570
E68 Sequelae of hyperalimentation
0.000 0.429 0.570
E65 Localised adiposity
0.000 0.429 0.570
E11.3 With ophthalmic complications
0.000 0.434 0.566
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.439 0.561
E70-E90 Metabolic disorders
0.000 0.448 0.552
E11.1 With ketoacidosis
0.000 0.453 0.547
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.458 0.542
E66.1 Drug-induced obesity
0.000 0.458 0.542
E66.0 Obesity due to excess calories
0.000 0.458 0.542
E14.3 With ophthalmic complications
0.000 0.468 0.532
E14.8 With unspecified complications
0.000 0.478 0.522
E14.7 With multiple complications
0.000 0.478 0.522
E14.6 With other specified complications
0.000 0.478 0.522
E14.5 With peripheral circulatory complications
0.000 0.478 0.522
E14.4 With neurological complications
0.000 0.478 0.522
E14.2 Withrenal complications
0.000 0.478 0.522
E14.1 With ketoacidosis
0.000 0.478 0.522
E14.0 With coma
0.000 0.478 0.522
E11.4 With neurological complications
0.000 0.479 0.520
E05.8 Other thyrotoxicosis
0.000 0.500 0.500
E05.5 Thyroid crisis or storm
0.000 0.500 0.500
E05.4 Thyrotoxicosis factitia
0.000 0.500 0.500
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.500 0.500
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.500 0.500
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.500 0.500
E53 Deficiency of other B group vitamins
0.000 0.506 0.494
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.517 0.483
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.536 0.464
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.539 0.461
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.551 0.449
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.551 0.449
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.551 0.449
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.551 0.449
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.551 0.449
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.551 0.449
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.551 0.449
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.551 0.449
E06.9 Thyroiditis, unspecified
0.000 0.551 0.449
E06.5 Other chronic thyroiditis
0.000 0.551 0.449
E06.4 Drug-induced thyroiditis
0.000 0.551 0.449
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.551 0.449
E06.1 Subacute thyroiditis
0.000 0.551 0.449
E06.0 Acute thyroiditis
0.000 0.551 0.449
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.551 0.448
E63 Other nutritional deficiencies
0.000 0.551 0.448
E61 Deficiency of other nutrient elements
0.000 0.551 0.448
E56 Other vitamin deficiencies
0.000 0.551 0.448
E51 Thiamine deficiency
0.000 0.551 0.448
E50 Vitamin A deficiency
0.000 0.551 0.448
E60 Dietary zinc deficiency
0.000 0.551 0.448
E59 Dietary selenium deficiency
0.000 0.551 0.448
E58 Dietary calcium deficiency
0.000 0.551 0.448
E54 Ascorbic acid deficiency
0.000 0.551 0.448
E52 Niacin deficiency [pellagra]
0.000 0.551 0.448
E06.3 Autoimmune thyroiditis
0.000 0.551 0.448
E83 Disorders of mineral metabolism
0.000 0.566 0.434
E12.9 Without complications
0.000 0.568 0.432
E12.8 With unspecified complications
0.000 0.568 0.432
E12.7 With multiple complications
0.000 0.568 0.432
E12.6 With other specified complications
0.000 0.568 0.432
E12.5 With peripheral circulatory complications
0.000 0.568 0.432
E12.4 With neurological complications
0.000 0.568 0.432
E12.3 With ophthalmic complications
0.000 0.568 0.432
E12.2 With renal complications
0.000 0.568 0.432
E12.1 With ketoacidosis
0.000 0.568 0.432
E12.0 With coma
0.000 0.568 0.432
E13.9 Without complications
0.000 0.568 0.432
E13.8 With unspecified complications
0.000 0.568 0.432
E13.7 With multiple complications
0.000 0.568 0.432
E13.6 With other specified complications
0.000 0.568 0.432
E13.5 With peripheral circulatory complications
0.000 0.568 0.432
E13.4 With neurological complications
0.000 0.568 0.432
E13.3 With ophthalmic complications
0.000 0.568 0.432
E13.2 With renal complications
0.000 0.568 0.432
E13.1 With ketoacidosis
0.000 0.568 0.432
E13.0 With coma
0.000 0.568 0.432
E07.8 Other specified disorders of thyroid
0.000 0.573 0.427
E07.1 Dyshormogenetic goitre
0.000 0.573 0.427
E07.0 Hypersecretion of calcitonin
0.000 0.573 0.427
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.579 0.421
E45 Retarded development following protein-energy malnutrition
0.000 0.579 0.421
E43 Unspecified severe protein-energy malnutrition
0.000 0.579 0.421
E42 Marasmic kwashiorkor
0.000 0.579 0.421
E41 Nutritional marasmus
0.000 0.579 0.421
E40 Kwashiorkor
0.000 0.579 0.421
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.584 0.416
E89.0 Postprocedural hypothyroidism
0.000 0.588 0.411
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.590 0.410
E34 Other endocrine disorders
0.000 0.590 0.410
E32 Diseases of thymus
0.000 0.590 0.410
E31 Polyglandular dysfunction
0.000 0.590 0.410
E30 Disorders of puberty, not elsewhere classified
0.000 0.590 0.410
E29 Testicular dysfunction
0.000 0.590 0.410
E26 Hyperaldosteronism
0.000 0.590 0.410
E25 Adrenogenital disorders
0.000 0.590 0.410
E20 Hypoparathyroidism
0.000 0.590 0.410
E23 Hypofunction and other disorders of pituitary gland
0.000 0.590 0.410
E67.8 Other specified hyperalimentation
0.000 0.591 0.409
E67.3 Hypervitaminosis D
0.000 0.591 0.409
E67.2 Megavitamin-B6 syndrome
0.000 0.591 0.409
E67.1 Hypercarotenaemia
0.000 0.591 0.409
E67.0 Hypervitaminosis A
0.000 0.591 0.409
E55 Vitamin D deficiency
0.000 0.592 0.407
E15 Nondiabetic hypoglycaemic coma
0.000 0.598 0.402
E53.8 Deficiency of other specified B group vitamins
0.000 0.600 0.400
E46 Unspecified protein-energy malnutrition
0.000 0.602 0.398
E83.5 Disorders of calcium metabolism
0.000 0.603 0.397
E85 Amyloidosis
0.000 0.604 0.396
E84 Cystic fibrosis
0.000 0.604 0.396
E79 Disorders of purine and pyrimidine metabolism
0.000 0.604 0.396
E77 Disorders of glycoprotein metabolism
0.000 0.604 0.396
E76 Disorders of glycosaminoglycan metabolism
0.000 0.604 0.396
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.604 0.396
E74 Other disorders of carbohydrate metabolism
0.000 0.604 0.396
E73 Lactose intolerance
0.000 0.604 0.396
E72 Other disorders of amino-acid metabolism
0.000 0.604 0.396
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.604 0.396
E70 Disorders of aromatic amino-acid metabolism
0.000 0.604 0.396
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.604 0.396
E07.9 Disorder of thyroid, unspecified
0.000 0.604 0.395
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.608 0.392
E27 Other disorders of adrenal gland
0.000 0.610 0.390
E22 Hyperfunction of pituitary gland
0.000 0.616 0.384
E28 Ovarian dysfunction
0.000 0.620 0.380
E24 Cushing's syndrome
0.000 0.622 0.377
E21.3 Hyperparathyroidism, unspecified
0.000 0.628 0.371
E04 Other non-toxic goitre
0.000 0.635 0.365
E87.6 Hypokalaemia
0.000 0.636 0.364
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.637 0.363
E21.0 Primary hyperparathyroidism
0.000 0.645 0.355
E53.9 Vitamin B deficiency, unspecified
0.000 0.645 0.354
E53.1 Pyridoxine deficiency
0.000 0.645 0.354
E53.0 Riboflavin deficiency
0.000 0.645 0.354
E78.5 Hyperlipidaemia, unspecified
0.000 0.646 0.354
E16 Other disorders of pancreatic internal secretion
0.000 0.647 0.353
E88 Other metabolic disorders
0.000 0.654 0.345
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.659 0.341
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.667 0.333
E21.4 Other specified disorders of parathyroid gland
0.000 0.667 0.333
E21.2 Other hyperparathyroidism
0.000 0.667 0.333
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.667 0.333
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.669 0.331
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.669 0.331
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.669 0.331
E89.5 Postprocedural testicular hypofunction
0.000 0.669 0.331
E89.4 Postprocedural ovarian failure
0.000 0.669 0.331
E89.2 Postprocedural hypoparathyroidism
0.000 0.669 0.331
E89.1 Postprocedural hypoinsulinaemia
0.000 0.669 0.331
E50.9 Vitamin A deficiency, unspecified
0.000 0.678 0.322
E50.8 Other manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.678 0.322
E50.5 Vitamin A deficiency with night blindness
0.000 0.678 0.322
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.678 0.322
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.678 0.322
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.678 0.322
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.678 0.322
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.678 0.322
E51.9 Thiamine deficiency, unspecified
0.000 0.678 0.322
E51.8 Other manifestations of thiamine deficiency
0.000 0.678 0.322
E51.2 Wernicke's encephalopathy
0.000 0.678 0.322
E51.1 Beriberi
0.000 0.678 0.322
E56.9 Vitamin deficiency, unspecified
0.000 0.678 0.322
E56.8 Deficiency of other vitamins
0.000 0.678 0.322
E56.1 Deficiency of vitamin K
0.000 0.678 0.322
E56.0 Deficiency of vitamin E
0.000 0.678 0.322
E61.9 Deficiency of nutrient element, unspecified
0.000 0.678 0.322
E61.8 Deficiency of other specified nutrient elements
0.000 0.678 0.322
E61.7 Deficiency of multiple nutrient elements
0.000 0.678 0.322
E61.6 Vanadium deficiency
0.000 0.678 0.322
E61.5 Molybdenum deficiency
0.000 0.678 0.322
E61.4 Chromium deficiency
0.000 0.678 0.322
E61.3 Manganese deficiency
0.000 0.678 0.322
E61.2 Magnesium deficiency
0.000 0.678 0.322
E61.1 Iron deficiency
0.000 0.678 0.322
E61.0 Copper deficiency
0.000 0.678 0.322
E63.9 Nutritional deficiency, unspecified
0.000 0.678 0.322
E63.8 Other specified nutritional deficiencies
0.000 0.678 0.322
E63.1 Imbalance of constituents of food intake
0.000 0.678 0.322
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.678 0.322
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.678 0.322
E64.8 Sequelae of other nutritional deficiencies
0.000 0.678 0.322
E64.3 Sequelae of rickets
0.000 0.678 0.322
E64.2 Sequelae of vitamin C deficiency
0.000 0.678 0.322
E64.1 Sequelae of vitamin A deficiency
0.000 0.678 0.322
E64.0 Sequelae of protein-energy malnutrition
0.000 0.678 0.322
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.689 0.311
E83.8 Other disorders of mineral metabolism
0.000 0.689 0.311
E83.2 Disorders of zinc metabolism
0.000 0.689 0.311
E83.0 Disorders of copper metabolism
0.000 0.689 0.311
E44.1 Mild protein-energy malnutrition
0.000 0.698 0.302
E44.0 Moderate protein-energy malnutrition
0.000 0.698 0.302
E10 Insulin-dependent diabetes mellitus
0.000 0.700 0.300
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.701 0.298
E87.4 Mixed disorder of acid-base balance
0.000 0.701 0.298
E87.0 Hyperosmolality and hypernatraemia
0.000 0.701 0.298
E20.9 Hypoparathyroidism, unspecified
0.000 0.706 0.294
E20.8 Other hypoparathyroidism
0.000 0.706 0.294
E20.1 Pseudohypoparathyroidism
0.000 0.706 0.294
E20.0 Idiopathic hypoparathyroidism
0.000 0.706 0.294
E25.9 Adrenogenital disorder, unspecified
0.000 0.706 0.294
E25.8 Other adrenogenital disorders
0.000 0.706 0.294
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.706 0.294
E26.9 Hyperaldosteronism, unspecified
0.000 0.706 0.294
E26.8 Other hyperaldosteronism
0.000 0.706 0.294
E26.1 Secondary hyperaldosteronism
0.000 0.706 0.294
E26.0 Primary hyperaldosteronism
0.000 0.706 0.294
E29.9 Testicular dysfunction, unspecified
0.000 0.706 0.294
E29.8 Other testicular dysfunction
0.000 0.706 0.294
E29.1 Testicular hypofunction
0.000 0.706 0.294
E29.0 Testicular hyperfunction
0.000 0.706 0.294
E30.9 Disorder of puberty, unspecified
0.000 0.706 0.294
E30.8 Other disorders of puberty
0.000 0.706 0.294
E30.1 Precocious puberty
0.000 0.706 0.294
E30.0 Delayed puberty
0.000 0.706 0.294
E31.9 Polyglandular dysfunction, unspecified
0.000 0.706 0.294
E31.8 Other polyglandular dysfunction
0.000 0.706 0.294
E31.1 Polyglandular hyperfunction
0.000 0.706 0.294
E31.0 Autoimmune polyglandular failure
0.000 0.706 0.294
E32.9 Disease of thymus, unspecified
0.000 0.706 0.294
E32.8 Other diseases of thymus
0.000 0.706 0.294
E32.1 Abscess of thymus
0.000 0.706 0.294
E32.0 Persistent hyperplasia of thymus
0.000 0.706 0.294
E34.9 Endocrine disorder, unspecified
0.000 0.706 0.294
E34.8 Other specified endocrine disorders
0.000 0.706 0.294
E34.5 Androgen resistance syndrome
0.000 0.706 0.294
E34.4 Constitutional tall stature
0.000 0.706 0.294
E34.3 Short stature, not elsewhere classified
0.000 0.706 0.294
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.706 0.294
E34.1 Other hypersecretion of intestinal hormones
0.000 0.706 0.294
E34.0 Carcinoid syndrome
0.000 0.706 0.294
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.706 0.294
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.706 0.294
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.706 0.294
E23.7 Disorder of pituitary gland, unspecified
0.000 0.706 0.294
E23.6 Other disorders of pituitary gland
0.000 0.706 0.294
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.706 0.294
E23.2 Diabetes insipidus
0.000 0.706 0.294
E23.1 Drug-induced hypopituitarism
0.000 0.706 0.294
E23.0 Hypopituitarism
0.000 0.706 0.294
E83.3 Disorders of phosphorus metabolism
0.000 0.707 0.293
E55.0 Rickets, active
0.000 0.707 0.292
E89.3 Postprocedural hypopituitarism
0.000 0.708 0.292
E87.7 Fluid overload
0.000 0.710 0.290
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.716 0.284
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.716 0.284
E70.3 Albinism
0.000 0.716 0.284
E70.2 Disorders of tyrosine metabolism
0.000 0.716 0.284
E70.1 Other hyperphenylalaninaemias
0.000 0.716 0.284
E70.0 Classical phenylketonuria
0.000 0.716 0.284
E71.3 Disorders of fatty-acid metabolism
0.000 0.716 0.284
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.716 0.284
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.716 0.284
E71.0 Maple-syrup-urine disease
0.000 0.716 0.284
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.716 0.284
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.716 0.284
E72.5 Disorders of glycine metabolism
0.000 0.716 0.284
E72.4 Disorders of ornithine metabolism
0.000 0.716 0.284
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.716 0.284
E72.2 Disorders of urea cycle metabolism
0.000 0.716 0.284
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.716 0.284
E72.0 Disorders of amino-acid transport
0.000 0.716 0.284
E73.9 Lactose intolerance, unspecified
0.000 0.716 0.284
E73.8 Other lactose intolerance
0.000 0.716 0.284
E73.1 Secondary lactase deficiency
0.000 0.716 0.284
E73.0 Congenital lactase deficiency
0.000 0.716 0.284
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.716 0.284
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.716 0.284
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.716 0.284
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.716 0.284
E74.2 Disorders of galactose metabolism
0.000 0.716 0.284
E74.1 Disorders of fructose metabolism
0.000 0.716 0.284
E74.0 Glycogen storage disease
0.000 0.716 0.284
E75.6 Lipid storage disorder, unspecified
0.000 0.716 0.284
E75.5 Other lipid storage disorders
0.000 0.716 0.284
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.716 0.284
E75.3 Sphingolipidosis, unspecified
0.000 0.716 0.284
E75.2 Other sphingolipidosis
0.000 0.716 0.284
E75.1 Other gangliosidosis
0.000 0.716 0.284
E75.0 GM2 gangliosidosis
0.000 0.716 0.284
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.716 0.284
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.716 0.284
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.716 0.284
E76.2 Other mucopolysaccharidoses
0.000 0.716 0.284
E76.1 Mucopolysaccharidosis, type II
0.000 0.716 0.284
E76.0 Mucopolysaccharidosis, type I
0.000 0.716 0.284
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.716 0.284
E77.8 Other disorders of glycoprotein metabolism
0.000 0.716 0.284
E77.1 Defects in glycoprotein degradation
0.000 0.716 0.284
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.716 0.284
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.716 0.284
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.716 0.284
E79.1 Lesch-Nyhan syndrome
0.000 0.716 0.284
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.716 0.284
E84.9 Cystic fibrosis, unspecified
0.000 0.716 0.284
E84.8 Cystic fibrosis with other manifestations
0.000 0.716 0.284
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.716 0.284
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.716 0.284
E85.9 Amyloidosis, unspecified
0.000 0.716 0.284
E85.8 Other amyloidosis
0.000 0.716 0.284
E85.4 Organ-limited amyloidosis
0.000 0.716 0.284
E85.3 Secondary systemic amyloidosis
0.000 0.716 0.284
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.716 0.284
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.716 0.284
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.716 0.284
E78.6 Lipoprotein deficiency
0.000 0.719 0.281
E78.4 Other hyperlipidaemia
0.000 0.719 0.281
E78.3 Hyperchylomicronaemia
0.000 0.719 0.281
E78.1 Pure hyperglyceridaemia
0.000 0.719 0.281
E87.3 Alkalosis
0.000 0.720 0.280
E27.9 Disorder of adrenal gland, unspecified
0.000 0.720 0.279
E27.8 Other specified disorders of adrenal gland
0.000 0.720 0.279
E27.5 Adrenomedullary hyperfunction
0.000 0.720 0.279
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.720 0.279
E27.2 Addisonian crisis
0.000 0.720 0.279
E27.0 Other adrenocortical overactivity
0.000 0.720 0.279
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.724 0.276
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.725 0.275
E22.8 Other hyperfunction of pituitary gland
0.000 0.725 0.275
E22.1 Hyperprolactinaemia
0.000 0.725 0.275
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.726 0.274
E28.9 Ovarian dysfunction, unspecified
0.000 0.727 0.272
E28.8 Other ovarian dysfunction
0.000 0.727 0.272
E28.3 Primary ovarian failure
0.000 0.727 0.272
E28.1 Androgen excess
0.000 0.727 0.272
E28.0 Oestrogen excess
0.000 0.727 0.272
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.729 0.271
E24.8 Other Cushing's syndrome
0.000 0.729 0.271
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.729 0.271
E24.3 Ectopic ACTH syndrome
0.000 0.729 0.271
E24.2 Drug-induced Cushing's syndrome
0.000 0.729 0.271
E24.1 Nelson's syndrome
0.000 0.729 0.271
E24.0 Pituitary-dependent Cushing's disease
0.000 0.729 0.271
E27.1 Primary adrenocortical insufficiency
0.000 0.734 0.265
E83.4 Disorders of magnesium metabolism
0.000 0.736 0.263
E04.8 Other specified non-toxic goitre
0.000 0.738 0.262
E04.0 Non-toxic diffuse goitre
0.000 0.738 0.262
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.739 0.260
E80.6 Other disorders of bilirubin metabolism
0.000 0.739 0.260
E80.5 Crigler-Najjar syndrome
0.000 0.739 0.260
E80.3 Defects of catalase and peroxydase
0.000 0.739 0.260
E80.2 Other porphyria
0.000 0.739 0.260
E80.1 Porphyria cutanea tarda
0.000 0.739 0.260
E80.0 Hereditary erythropoietic porphyria
0.000 0.739 0.260
E78.8 Other disorders of lipoprotein metabolism
0.000 0.740 0.260
E83.1 Disorders of iron metabolism
0.000 0.741 0.259
E87.5 Hyperkalaemia
0.000 0.741 0.259
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.747 0.253
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.747 0.253
E16.4 Abnormal secretion of gastrin
0.000 0.747 0.253
E16.3 Increased secretion of glucagon
0.000 0.747 0.253
E16.1 Other hypoglycaemia
0.000 0.747 0.253
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.747 0.253
E55.9 Vitamin D deficiency, unspecified
0.000 0.748 0.251
E22.0 Acromegaly and pituitary gigantism
0.000 0.752 0.248
E88.9 Metabolic disorder, unspecified
0.000 0.752 0.248
E88.8 Other specified metabolic disorders
0.000 0.752 0.248
E88.3 Tumour lysis syndrome
0.000 0.752 0.248
E88.2 Lipomatosis, not elsewhere classified
0.000 0.752 0.248
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.752 0.248
E28.2 Polycystic ovarian syndrome
0.000 0.757 0.242
E24.9 Cushing's syndrome, unspecified
0.000 0.762 0.238
K90.0 Coeliac disease
0.000 0.765 0.235
E04.2 Non-toxic multinodular goitre
0.000 0.771 0.229
E78.2 Mixed hyperlipidaemia
0.000 0.771 0.229
E80.4 Gilbert's syndrome
0.000 0.772 0.228
E04.9 Non-toxic goitre, unspecified
0.001 0.782 0.217
E10.8 With unspecified complications
0.000 0.785 0.215
E10.7 With multiple complications
0.000 0.785 0.215
E10.6 With other specified complications
0.000 0.785 0.215
E10.5 With peripheral circulatory complications
0.000 0.785 0.215
E10.0 With coma
0.000 0.785 0.215
E10.1 With ketoacidosis
0.000 0.785 0.215
E78.0 Pure hypercholesterolaemia
0.000 0.785 0.215
E87.2 Acidosis
0.000 0.787 0.213
E86 Volume depletion
0.000 0.793 0.207
E16.2 Hypoglycaemia, unspecified
0.000 0.796 0.204
E10.3 With ophthalmic complications
0.000 0.797 0.203
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.802 0.198
E10.4 With neurological complications
0.000 0.810 0.190
E10.2 With renal complications
0.000 0.812 0.187
E04.1 Non-toxic single thyroid nodule
0.001 0.827 0.172
K90 Intestinal malabsorption
0.005 0.895 0.101
E10.9 Without complications
0.000 0.895 0.104
K90.8 Other intestinal malabsorption
0.004 0.924 0.072
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.004 0.924 0.072
K90.3 Pancreatic steatorrhoea
0.004 0.924 0.072
K90.2 Blind loop syndrome, not elsewhere classified
0.004 0.924 0.072
K90.1 Tropical sprue
0.004 0.924 0.072
K90.9 Intestinal malabsorption, unspecified
0.004 0.927 0.069
K51 Ulcerative colitis
0.029 0.971 0.000
K51.2 Ulcerative (chronic) proctitis
0.028 0.972 0.000
K50-K52 Noninfective enteritis and colitis
0.027 0.973 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.026 0.974 0.000
K50 Crohn's disease [regional enteritis]
0.024 0.976 0.000
K90-K93 Other diseases of the digestive system
0.011 0.976 0.013
K51.9 Ulcerative colitis, unspecified
0.023 0.976 0.000
S52.50 Fracture of lower end of radius (closed)
0.000 0.977 0.023
K52 Other non-infective gastro-enteritis and colitis
0.022 0.978 0.000
K51.8 Other ulcerative colitis
0.022 0.978 0.000
K50.1 Crohn's disease of large intestine
0.022 0.978 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.022 0.978 0.000
K22 Other diseases of oesophagus
0.022 0.978 0.000
K51.5 Mucosal proctocolitis
0.021 0.979 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.021 0.979 0.000
K51.4 Pseudopolyposis of colon
0.020 0.979 0.000
K50.0 Crohn's disease of small intestine
0.020 0.980 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.020 0.980 0.000
Chapter XI Diseases of the digestive system
0.020 0.980 0.000
K22.8 Other specified diseases of oesophagus
0.020 0.980 0.000
K22.1 Ulcer of oesophagus
0.019 0.981 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.019 0.981 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.019 0.981 0.000
K82 Other diseases of gallbladder
0.019 0.981 0.000
K22.9 Disease of oesophagus, unspecified
0.019 0.981 0.000
I10 Essential (primary) hypertension
0.000 0.981 0.019
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.019 0.981 0.000
K82.8 Other specified diseases of gallbladder
0.019 0.981 0.000
K22.2 Oesophageal obstruction
0.019 0.981 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.018 0.982 0.000
K70-K77 Diseases of liver
0.018 0.982 0.000
K31 Other diseases of stomach and duodenum
0.018 0.982 0.000
K21 Gastro-oesophageal reflux disease
0.018 0.982 0.000
K50.8 Other Crohn's disease
0.018 0.982 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.008 0.982 0.009
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.018 0.982 0.000
K31.8 Other specified diseases of stomach and duodenum
0.018 0.982 0.000
K08 Other disorders of teeth and supporting structures
0.017 0.983 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.017 0.983 0.000
K82.1 Hydrops of gallbladder
0.017 0.983 0.000
K08.3 Retained dental root
0.017 0.983 0.000
K09 Cysts of oral region, not elsewhere classified
0.017 0.983 0.000
K22.7 Barrett's oesophagus
0.017 0.983 0.000
K52.3 Indeterminate colitis
0.016 0.984 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.016 0.984 0.000
K52.1 Toxic gastro-enteritis and colitis
0.016 0.984 0.000
K74 Fibrosis and cirrhosis of liver
0.016 0.984 0.000
K22.5 Diverticulum of oesophagus, acquired
0.016 0.984 0.000
K22.3 Perforation of oesophagus
0.016 0.984 0.000
K22.0 Achalasia of cardia
0.016 0.984 0.000
K25 Gastric ulcer
0.016 0.984 0.000
K04 Diseases of pulp and periapical tissues
0.015 0.984 0.000
K27 Peptic ulcer, site unspecified
0.015 0.984 0.000
K82.9 Disease of gallbladder, unspecified
0.015 0.985 0.000
K86 Other diseases of pancreas
0.015 0.985 0.000
K07 Dentofacial anomalies [including malocclusion]
0.015 0.985 0.000
K11 Diseases of salivary glands
0.015 0.985 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.009 0.985 0.005
K65-K67 Diseases of peritoneum
0.015 0.985 0.000
K02 Dental caries
0.015 0.985 0.000
K05 Gingivitis and periodontal diseases
0.015 0.985 0.000
K72 Hepatic failure, not elsewhere classified
0.014 0.985 0.000
K09.0 Developmental odontogenic cysts
0.014 0.985 0.000
K50.9 Crohn's disease, unspecified
0.014 0.985 0.000
K76 Other diseases of liver
0.014 0.986 0.000
K00 Disorders of tooth development and eruption
0.014 0.986 0.000
K28 Gastrojejunal ulcer
0.014 0.986 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.014 0.986 0.000
K14 Diseases of tongue
0.014 0.986 0.000
K74.6 Other and unspecified cirrhosis of liver
0.014 0.986 0.000
K03 Other diseases of hard tissues of teeth
0.014 0.986 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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