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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74367134
log Bayes Factor = 15.2023
Chromosome 4   position 115,387,129  (GRCh37) Explore rs74367134 on Ensembl!
Variant rs74367134 is part of Cluster X0181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
M81 Osteoporosis without pathological fracture
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
M81.9 Osteoporosis, unspecified
0.995 0.005 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.995 0.005 0.000
N10-N16 Renal tubulo-interstitial diseases
0.992 0.008 0.000
M13 Other arthritis
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
M79.6 Pain in limb
0.991 0.009 0.000
M13.9 Arthritis, unspecified
0.990 0.010 0.000
E87.5 Hyperkalaemia
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
N17-N19 Renal failure
0.987 0.013 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
E86 Volume depletion
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.978 0.022 0.000
Chapter V Mental and behavioural disorders
0.977 0.023 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.971 0.029 0.000
N13 Obstructive and reflux uropathy
0.971 0.029 0.000
N17 Acute renal failure
0.970 0.030 0.000
E83 Disorders of mineral metabolism
0.962 0.038 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.961 0.039 0.000
N17.9 Acute renal failure, unspecified
0.958 0.042 0.000
M79.8 Other specified soft tissue disorders
0.956 0.044 0.000
E87.6 Hypokalaemia
0.951 0.049 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.950 0.050 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.948 0.052 0.000
B95-B98 Bacterial, viral and other infectious agents
0.943 0.057 0.000
M79.66 Pain in limb (Lower leg)
0.942 0.058 0.000
F30-F39 Mood [affective] disorders
0.936 0.064 0.000
N18 Chronic renal failure
0.935 0.065 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.934 0.066 0.000
M54 Dorsalgia
0.933 0.067 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.933 0.067 0.000
E87.2 Acidosis
0.932 0.068 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.931 0.069 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.930 0.070 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.926 0.074 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.926 0.074 0.000
N00-N08 Glomerular diseases
0.924 0.076 0.000
Chapter VIII Diseases of the ear and mastoid process
0.923 0.077 0.000
M75 Shoulder lesions
0.918 0.082 0.000
M06 Other rheumatoid arthritis
0.917 0.083 0.000
A30-A49 Other bacterial diseases
0.913 0.087 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.913 0.087 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.908 0.092 0.000
M79.0 Rheumatism, unspecified
0.907 0.093 0.000
Chapter VI Diseases of the nervous system
0.903 0.097 0.000
E83.1 Disorders of iron metabolism
0.903 0.097 0.000
M13.94 Arthritis, unspecified (Hand)
0.902 0.098 0.000
F32 Depressive episode
0.900 0.100 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.900 0.100 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.895 0.105 0.000
H90-H95 Other disorders of ear
0.895 0.105 0.000
S70-S79 Injuries to the hip and thigh
0.888 0.112 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.887 0.113 0.000
F20 Schizophrenia
0.880 0.120 0.000
M50 Cervical disk disorders
0.879 0.121 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.878 0.122 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.875 0.125 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.871 0.129 0.000
N18.2 Chronic kidney disease, stage 2
0.866 0.134 0.000
E88 Other metabolic disorders
0.865 0.135 0.000
H90 Conductive and sensorineural hearing loss
0.864 0.136 0.000
O26.8 Other specified pregnancy-related conditions
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.857 0.143 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.853 0.147 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.853 0.147 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.852 0.148 0.000
S50-S59 Injuries to the elbow and forearm
0.847 0.153 0.000
T92 Sequelae of injuries of upper limb
0.845 0.155 0.000
Chapter XI Diseases of the digestive system
0.845 0.155 0.000
E83.4 Disorders of magnesium metabolism
0.842 0.158 0.000
Y45.0 Opioids and related analgesics
0.842 0.158 0.000
N25-N29 Other disorders of kidney and ureter
0.840 0.160 0.000
M86-M90 Other osteopathies
0.840 0.160 0.000
B35-B49 Mycoses
0.837 0.163 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.836 0.164 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.836 0.164 0.000
M54.2 Cervicalgia
0.835 0.165 0.000
T90 Sequelae of injuries of head
0.833 0.167 0.000
M79.64 Pain in limb (Hand)
0.832 0.168 0.000
N03 Chronic nephritic syndrome
0.827 0.173 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.823 0.177 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.822 0.178 0.000
F20.9 Schizophrenia, unspecified
0.822 0.178 0.000
K70-K77 Diseases of liver
0.821 0.179 0.000
M76 Enthesopathies of lower limb, excluding foot
0.820 0.180 0.000
V20-V29 Motorcycle rider injured in transport accident
0.819 0.181 0.000
Chapter II Neoplasms
0.819 0.181 0.000
M06.9 Rheumatoid arthritis, unspecified
0.819 0.181 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.819 0.181 0.000
M80 Osteoporosis with pathological fracture
0.817 0.183 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.817 0.183 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.816 0.184 0.000
E87.7 Fluid overload
0.816 0.184 0.000
M79.1 Myalgia
0.816 0.184 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.814 0.186 0.000
M75.4 Impingement syndrome of shoulder
0.810 0.190 0.000
N18.5 Chronic kidney disease, stage 5
0.808 0.192 0.000
K65-K67 Diseases of peritoneum
0.808 0.192 0.000
N13.8 Other obstructive and reflux uropathy
0.808 0.192 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.804 0.196 0.000
C15-C26 Malignant neoplasms of digestive organs
0.803 0.197 0.000
M84 Disorders of continuity of bone
0.802 0.198 0.000
M54.4 Lumbago with sciatica
0.801 0.199 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.800 0.200 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.799 0.201 0.000
M79.69 Pain in limb (Site unspecified)
0.799 0.201 0.000
M79.7 Fibromyalgia
0.799 0.201 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.798 0.202 0.000
M54.9 Dorsalgia, unspecified
0.796 0.204 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.794 0.206 0.000
X20-X29 Contact with venomous animals and plants
0.794 0.206 0.000
M77 Other enthesopathies
0.793 0.206 0.000
O00-O08 Pregnancy with abortive outcome
0.793 0.207 0.000
F32.1 Moderate depressive episode
0.791 0.209 0.000
M00-M03 Infectious arthropathies
0.790 0.210 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.789 0.211 0.000
A46 Erysipelas
0.788 0.212 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.788 0.212 0.000
M79.60 Pain in limb (Multiple sites)
0.787 0.213 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.786 0.213 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.783 0.217 0.000
Y42.7 Androgens and anabolic congeners
0.783 0.217 0.000
S52 Fracture of forearm
0.783 0.217 0.000
H90.2 Conductive hearing loss, unspecified
0.782 0.218 0.000
T79-T79 Certain early complications of trauma
0.781 0.218 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.780 0.220 0.000
K55-K64 Other diseases of intestines
0.777 0.223 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
O60-O75 Complications of labour and delivery
0.775 0.225 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.775 0.225 0.000
M79.2 Neuralgia and neuritis, unspecified
0.775 0.225 0.000
T63 Toxic effect of contact with venomous animals
0.772 0.228 0.000
K63 Other diseases of intestine
0.771 0.229 0.000
O85-O92 Complications predominantly related to the puerperium
0.771 0.229 0.000
A15-A19 Tuberculosis
0.770 0.230 0.000
G35 Multiple sclerosis
0.770 0.230 0.000
K63.5 Polyp of colon
0.768 0.232 0.000
M50.2 Other cervical disk displacement
0.767 0.233 0.000
S72 Fracture of femur
0.767 0.233 0.000
M06.0 Seronegative rheumatoid arthritis
0.766 0.234 0.000
M45-M49 Spondylopathies
0.765 0.235 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.764 0.236 0.000
F32.9 Depressive episode, unspecified
0.763 0.237 0.000
W50-W64 Exposure to animate mechanical forces
0.762 0.238 0.000
S10-S19 Injuries to the neck
0.761 0.238 0.000
M60-M63 Disorders of muscles
0.761 0.239 0.000
Y45.1 Salicylates
0.759 0.241 0.000
N03.9 Unspecified
0.758 0.242 0.000
E73 Lactose intolerance
0.757 0.243 0.000
A49 Bacterial infection of unspecified site
0.756 0.244 0.000
N11 Chronic tubulo-interstitial nephritis
0.755 0.245 0.000
C18 Malignant neoplasm of colon
0.754 0.246 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.753 0.247 0.000
T31 Burns classified according to extent of body surface involved
0.752 0.248 0.000
N99-N99 Other disorders of the genitourinary system
0.752 0.248 0.000
N18.0 End-stage renal disease
0.751 0.248 0.000
G95 Other diseases of spinal cord
0.751 0.249 0.000
M75.0 Adhesive capsulitis of shoulder
0.750 0.250 0.000
M79.63 Pain in limb (Forearm)
0.750 0.250 0.000
E85 Amyloidosis
0.749 0.251 0.000
V80-V89 Other land transport accidents
0.749 0.251 0.000
M75.3 Calcific tendinitis of shoulder
0.748 0.252 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.747 0.253 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.745 0.255 0.000
H92 Otalgia and effusion of ear
0.743 0.257 0.000
M72 Fibroblastic disorders
0.743 0.257 0.000
K66 Other disorders of peritoneum
0.742 0.258 0.000
M75.9 Shoulder lesion, unspecified
0.741 0.259 0.000
K74 Fibrosis and cirrhosis of liver
0.739 0.261 0.000
N10 Acute tubulo-interstitial nephritis
0.738 0.262 0.000
N04 Nephrotic syndrome
0.737 0.263 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.737 0.263 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.736 0.263 0.000
N18.3 Chronic kidney disease, stage 3
0.736 0.264 0.000
M54.22 Cervicalgia (Cervical region)
0.734 0.266 0.000
Y44 Agents primarily affecting blood constituents
0.733 0.267 0.000
B15-B19 Viral hepatitis
0.733 0.267 0.000
F45 Somatoform disorders
0.732 0.268 0.000
M81.4 Drug-induced osteoporosis
0.732 0.268 0.000
M53 Other dorsopathies, not elsewhere classified
0.732 0.268 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.731 0.269 0.000
N13.6 Pyonephrosis
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.729 0.270 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.729 0.271 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.727 0.273 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.727 0.273 0.000
T91 Sequelae of injuries of neck and trunk
0.726 0.274 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.726 0.274 0.000
M71 Other bursopathies
0.725 0.274 0.000
F20.0 Paranoid schizophrenia
0.724 0.276 0.000
F22 Persistent delusional disorders
0.724 0.276 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
C50-C50 Malignant neoplasm of breast
0.724 0.276 0.000
M85 Other disorders of bone density and structure
0.723 0.276 0.000
F99-F99 Unspecified mental disorder
0.723 0.277 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.722 0.278 0.000
A41 Other septicaemia
0.722 0.278 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.722 0.278 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
M40-M43 Deforming dorsopathies
0.722 0.278 0.000
F32.0 Mild depressive episode
0.721 0.279 0.000
T56 Toxic effect of metals
0.721 0.279 0.000
T23 Burn and corrosion of wrist and hand
0.720 0.280 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.720 0.280 0.000
H93 Other disorders of ear, not elsewhere classified
0.719 0.281 0.000
M54.3 Sciatica
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E87.4 Mixed disorder of acid-base balance
0.717 0.283 0.000
M79.9 Soft tissue disorder, unspecified
0.717 0.283 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.717 0.283 0.000
M79.3 Panniculitis, unspecified
0.717 0.283 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.716 0.284 0.000
K65 Peritonitis
0.716 0.284 0.000
M83 Adult osteomalacia
0.716 0.284 0.000
M82 Osteoporosis in diseases classified elsewhere
0.716 0.284 0.000
F30 Manic episode
0.715 0.285 0.000
M81.8 Other osteoporosis
0.715 0.285 0.000
M81.6 Localised osteoporosis [Lequesne]
0.715 0.285 0.000
M81.5 Idiopathic osteoporosis
0.715 0.285 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.715 0.285 0.000
M81.2 Osteoporosis of disuse
0.715 0.285 0.000
M81.1 Postoophorectomy osteoporosis
0.715 0.285 0.000
M81.0 Postmenopausal osteoporosis
0.715 0.285 0.000
E83.5 Disorders of calcium metabolism
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.714 0.286 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.714 0.286 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.714 0.286 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.714 0.286 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.714 0.286 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.714 0.286 0.000
B44 Aspergillosis
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
M50.1 Cervical disk disorder with radiculopathy
0.712 0.288 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.711 0.288 0.000
N15 Other renal tubulo-interstitial diseases
0.711 0.288 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.711 0.288 0.000
M13.8 Other specified arthritis
0.711 0.288 0.000
M13.1 Monoarthritis, not elsewhere classified
0.711 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M79.68 Pain in limb (Other)
0.710 0.290 0.000
M79.61 Pain in limb (Shoulder region)
0.710 0.290 0.000
S52.0 Fracture of upper end of ulna
0.710 0.290 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.710 0.290 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.710 0.290 0.000
M75.2 Bicipital tendinitis
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
F60-F69 Disorders of adult personality and behaviour
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
T92.1 Sequelae of fracture of arm
0.707 0.293 0.000
H90.5 Sensorineural hearing loss, unspecified
0.706 0.294 0.000
O72 Postpartum haemorrhage
0.705 0.295 0.000
G20-G26 Extrapyramidal and movement disorders
0.705 0.295 0.000
E88.2 Lipomatosis, not elsewhere classified
0.705 0.295 0.000
T51 Toxic effect of alcohol
0.703 0.297 0.000
F31 Bipolar affective disorder
0.703 0.297 0.000
M13.93 Arthritis, unspecified (Forearm)
0.702 0.298 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.702 0.298 0.000
Y42.5 Other oestrogens and progestogens
0.702 0.298 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.701 0.299 0.000
F25 Schizoaffective disorders
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.701 0.299 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
M54.6 Pain in thoracic spine
0.699 0.301 0.000
O26.9 Pregnancy-related condition, unspecified
0.698 0.302 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.698 0.302 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.697 0.303 0.000
Y84.0 Cardiac catheterisation
0.697 0.303 0.000
Y95 Nosocomial condition
0.697 0.303 0.000
T90.1 Sequelae of open wound of head
0.697 0.303 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.304 0.000
N17.8 Other acute renal failure
0.695 0.304 0.000
N17.2 Acute renal failure with medullary necrosis
0.695 0.304 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.695 0.304 0.000
N17.0 Acute renal failure with tubular necrosis
0.695 0.304 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.695 0.305 0.000
T90.9 Sequelae of unspecified injury of head
0.695 0.305 0.000
C20 Malignant neoplasm of rectum
0.695 0.305 0.000
M89 Other disorders of bone
0.694 0.306 0.000
B91 Sequelae of poliomyelitis
0.694 0.306 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.693 0.307 0.000
F80-F89 Disorders of psychological development
0.691 0.309 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.691 0.309 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.691 0.309 0.000
M75.5 Bursitis of shoulder
0.691 0.309 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
K76 Other diseases of liver
0.691 0.309 0.000
M76.6 Achilles tendinitis
0.690 0.310 0.000
M79.62 Pain in limb (Upper arm)
0.690 0.310 0.000
E20-E35 Disorders of other endocrine glands
0.690 0.310 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.689 0.310 0.000
E83.8 Other disorders of mineral metabolism
0.689 0.310 0.000
E83.2 Disorders of zinc metabolism
0.689 0.310 0.000
E83.0 Disorders of copper metabolism
0.689 0.310 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.689 0.311 0.000
Y59 Other and unspecified vaccines and biological substances
0.689 0.311 0.000
Y58 Bacterial vaccines
0.689 0.311 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.689 0.311 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.689 0.311 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.689 0.311 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.689 0.311 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.311 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.689 0.311 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.689 0.311 0.000
T20 Burn and corrosion of head and neck
0.688 0.312 0.000
N02 Recurrent and persistent haematuria
0.688 0.312 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.688 0.312 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.688 0.312 0.000
M13.0 Polyarthritis, unspecified
0.688 0.312 0.000
W00-W19 Falls
0.687 0.313 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.687 0.313 0.000
K55 Vascular disorders of intestine
0.687 0.313 0.000
T90.5 Sequelae of intracranial injury
0.686 0.314 0.000
M79.88 Other specified soft tissue disorders (Other)
0.685 0.315 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.685 0.315 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.685 0.315 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.685 0.315 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.685 0.315 0.000
C18.7 Sigmoid colon
0.685 0.315 0.000
F45.8 Other somatoform disorders
0.684 0.316 0.000
M51 Other intervertebral disk disorders
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.682 0.317 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.682 0.318 0.000
S40-S49 Injuries to the shoulder and upper arm
0.682 0.318 0.000
E87.0 Hyperosmolality and hypernatraemia
0.681 0.318 0.000
T31.0 Burns involving less than 10% of body surface
0.681 0.319 0.000
T63.4 Venom of other arthropods
0.681 0.319 0.000
M81.98 Osteoporosis, unspecified (Other)
0.679 0.321 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.679 0.321 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.678 0.321 0.000
S72.0 Fracture of neck of femur
0.678 0.322 0.000
S71 Open wound of hip and thigh
0.678 0.322 0.000
C81 Hodgkin's disease
0.678 0.322 0.000
O20 Haemorrhage in early pregnancy
0.676 0.324 0.000
O23 Infections of genito-urinary tract in pregnancy
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
N13.4 Hydroureter
0.675 0.325 0.000
M79.5 Residual foreign body in soft tissue
0.675 0.325 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.675 0.325 0.000
G70-G73 Diseases of myoneural junction and muscle
0.674 0.325 0.000
S79 Other and unspecified injuries of hip and thigh
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.673 0.327 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.673 0.327 0.000
K75 Other inflammatory liver diseases
0.673 0.327 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.673 0.327 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.672 0.328 0.000
K66.0 Peritoneal adhesions
0.672 0.328 0.000
F38 Other mood [affective] disorders
0.671 0.329 0.000
F34 Persistent mood [affective] disorders
0.671 0.329 0.000
F39 Unspecified mood [affective] disorder
0.671 0.329 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.671 0.329 0.000
N18.8 Other chronic renal failure
0.670 0.329 0.000
N18.1 Chronic kidney disease, stage 1
0.670 0.329 0.000
S52.6 Fracture of lower end of both ulna and radius
0.670 0.330 0.000
S70 Superficial injury of hip and thigh
0.670 0.330 0.000
H60-H62 Diseases of external ear
0.670 0.330 0.000
M11 Other crystal arthropathies
0.670 0.330 0.000
M54.29 Cervicalgia-Site unspe
0.670 0.330 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.669 0.331 0.000
M54.8 Other dorsalgia
0.669 0.331 0.000
M54.0 Panniculitis affecting regions of neck and back
0.669 0.331 0.000
T98 Sequelae of other and unspecified effects of external causes
0.669 0.331 0.000
T95 Sequelae of burns, corrosions and frostbite
0.669 0.331 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.669 0.331 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.669 0.331 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.669 0.331 0.000
F29 Unspecified nonorganic psychosis
0.669 0.331 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.668 0.332 0.000
F23 Acute and transient psychotic disorders
0.667 0.333 0.000
F28 Other nonorganic psychotic disorders
0.667 0.333 0.000
F24 Induced delusional disorder
0.667 0.333 0.000
F21 Schizotypal disorder
0.667 0.333 0.000
M87 Osteonecrosis
0.666 0.334 0.000
A40 Streptococcal septicaemia
0.666 0.334 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.664 0.336 0.000
G37 Other demyelinating diseases of central nervous system
0.664 0.336 0.000
O02 Other abnormal products of conception
0.663 0.337 0.000
N26 Unspecified contracted kidney
0.663 0.337 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.662 0.337 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.662 0.338 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.662 0.338 0.000
N06 Isolated proteinuria with specified morphological lesion
0.662 0.338 0.000
N01 Rapidly progressive nephritic syndrome
0.662 0.338 0.000
N00 Acute nephritic syndrome
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.662 0.338 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.662 0.338 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.661 0.339 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
T59 Toxic effect of other gases, fumes and vapours
0.659 0.340 0.000
H92.1 Otorrhoea
0.659 0.341 0.000
S52.00 Fracture of upper end of ulna (closed)
0.659 0.341 0.000
M07 Psoriatic and enteropathic arthropathies
0.658 0.342 0.000
M75.8 Other shoulder lesions
0.658 0.342 0.000
M06.8 Other specified rheumatoid arthritis
0.657 0.343 0.000
M06.4 Inflammatory polyarthropathy
0.657 0.343 0.000
M06.3 Rheumatoid nodule
0.657 0.343 0.000
M06.2 Rheumatoid bursitis
0.657 0.343 0.000
M06.1 Adult-onset Still's disease
0.657 0.343 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.657 0.343 0.000
K70 Alcoholic liver disease
0.655 0.345 0.000
M90 Osteopathies in diseases classified elsewhere
0.655 0.345 0.000
C50 Malignant neoplasm of breast
0.655 0.345 0.000
M79.79 Fibromyalgia (Site unspecified)
0.655 0.345 0.000
X23 Contact with hornets, wasps and bees
0.654 0.345 0.000
A48 Other bacterial diseases, not elsewhere classified
0.654 0.346 0.000
A44 Bartonellosis
0.654 0.346 0.000
A43 Nocardiosis
0.654 0.346 0.000
A42 Actinomycosis
0.654 0.346 0.000
A39 Meningococcal infection
0.654 0.346 0.000
A37 Whooping cough
0.654 0.346 0.000
A36 Diphtheria
0.654 0.346 0.000
A32 Listeriosis
0.654 0.346 0.000
A31 Infection due to other mycobacteria
0.654 0.346 0.000
A30 Leprosy [Hansen's disease]
0.654 0.346 0.000
A38 Scarlet fever
0.654 0.346 0.000
A35 Other tetanus
0.654 0.346 0.000
A34 Obstetrical tetanus
0.654 0.346 0.000
A33 Tetanus neonatorum
0.654 0.346 0.000
O29 Complications of anaesthesia during pregnancy
0.654 0.346 0.000
O28 Abnormal findings on antenatal screening of mother
0.654 0.346 0.000
O22 Venous complications in pregnancy
0.654 0.346 0.000
O25 Malnutrition in pregnancy
0.654 0.346 0.000
S80-S89 Injuries to the knee and lower leg
0.654 0.346 0.000
G96 Other disorders of central nervous system
0.652 0.348 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.651 0.349 0.000
M79.16 Myalgia (Lower leg)
0.651 0.349 0.000
M50.3 Other cervical disk degeneration
0.651 0.349 0.000
A41.9 Septicaemia, unspecified
0.650 0.350 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.650 0.350 0.000
M79.08 Rheumatism, unspecified (Other)
0.650 0.350 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.650 0.350 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.650 0.350 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.650 0.350 0.000
M79.04 Rheumatism, unspecified (Hand)
0.650 0.350 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.650 0.350 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.650 0.350 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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