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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74664674
log Bayes Factor = 18.0774
Chromosome 8   position 105,468,730  (GRCh37) Explore rs74664674 on Ensembl!
Variant rs74664674 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.990 0.010 0.000
K80 Cholelithiasis
0.988 0.012 0.000
J30-J39 Other diseases of upper respiratory tract
0.986 0.014 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.985 0.015 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.983 0.017 0.000
M79.6 Pain in limb
0.982 0.018 0.000
R07 Pain in throat and chest
0.980 0.020 0.000
M75 Shoulder lesions
0.976 0.024 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
K86 Other diseases of pancreas
0.963 0.037 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.962 0.038 0.000
B35-B49 Mycoses
0.960 0.040 0.000
Chapter VIII Diseases of the ear and mastoid process
0.958 0.042 0.000
R07.4 Chest pain, unspecified
0.956 0.044 0.000
G40 Epilepsy
0.948 0.052 0.000
B95-B98 Bacterial, viral and other infectious agents
0.945 0.055 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.945 0.055 0.000
M79.66 Pain in limb (Lower leg)
0.944 0.056 0.000
S00-S09 Injuries to the head
0.942 0.058 0.000
J40-J47 Chronic lower respiratory diseases
0.941 0.059 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.940 0.060 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.939 0.061 0.000
B37 Candidiasis
0.929 0.071 0.000
G47 Sleep disorders
0.928 0.072 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.925 0.075 0.000
G20-G26 Extrapyramidal and movement disorders
0.922 0.078 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.919 0.081 0.000
T66-T78 Other and unspecified effects of external causes
0.911 0.089 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.910 0.090 0.000
J44 Other chronic obstructive pulmonary disease
0.910 0.090 0.000
W00-W19 Falls
0.909 0.091 0.000
M75.0 Adhesive capsulitis of shoulder
0.907 0.093 0.000
Y84.2 Radiological procedure and radiotherapy
0.904 0.096 0.000
A30-A49 Other bacterial diseases
0.900 0.100 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.899 0.101 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.899 0.101 0.000
S80-S89 Injuries to the knee and lower leg
0.899 0.101 0.000
J09-J18 Influenza and pneumonia
0.899 0.101 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.896 0.104 0.000
G40.9 Epilepsy, unspecified
0.895 0.105 0.000
R07.2 Precordial pain
0.894 0.106 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.890 0.110 0.000
B37.0 Candidal stomatitis
0.890 0.110 0.000
K83 Other diseases of biliary tract
0.889 0.111 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.884 0.116 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.883 0.117 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.881 0.119 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.880 0.120 0.000
S20-S29 Injuries to the thorax
0.874 0.126 0.000
J90-J94 Other diseases of pleura
0.871 0.129 0.000
G20 Parkinson's disease
0.868 0.132 0.000
R07.3 Other chest pain
0.863 0.137 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.863 0.137 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.862 0.138 0.000
S82 Fracture of lower leg, including ankle
0.861 0.139 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
K85 Acute pancreatitis
0.857 0.142 0.000
S01 Open wound of head
0.856 0.144 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.855 0.145 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.855 0.145 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.854 0.146 0.000
R26 Abnormalities of gait and mobility
0.853 0.147 0.000
H60-H62 Diseases of external ear
0.851 0.149 0.000
T78 Adverse effects, not elsewhere classified
0.848 0.152 0.000
W19 Unspecified fall
0.843 0.157 0.000
R06 Abnormalities of breathing
0.839 0.161 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.838 0.162 0.000
S00 Superficial injury of head
0.836 0.164 0.000
J34 Other disorders of nose and nasal sinuses
0.836 0.164 0.000
J36 Peritonsillar abscess
0.834 0.166 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.834 0.166 0.000
G47.9 Sleep disorder, unspecified
0.833 0.167 0.000
K83.8 Other specified diseases of biliary tract
0.832 0.168 0.000
J30 Vasomotor and allergic rhinitis
0.830 0.170 0.000
G62 Other polyneuropathies
0.829 0.171 0.000
S82.8 Fractures of other parts of lower leg
0.828 0.172 0.000
M75.3 Calcific tendinitis of shoulder
0.827 0.173 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.827 0.173 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.826 0.174 0.000
Y84.6 Urinary catheterisation
0.826 0.174 0.000
H80-H83 Diseases of inner ear
0.826 0.174 0.000
M79.62 Pain in limb (Upper arm)
0.826 0.174 0.000
K86.3 Pseudocyst of pancreas
0.825 0.175 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.825 0.175 0.000
Y84.8 Other medical procedures
0.823 0.177 0.000
R00 Abnormalities of heart beat
0.821 0.179 0.000
Y84.1 Kidney dialysis
0.819 0.181 0.000
S60-S69 Injuries to the wrist and hand
0.818 0.182 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.816 0.184 0.000
G41 Status epilepticus
0.816 0.184 0.000
Y86 Sequelae of other accidents
0.816 0.184 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.814 0.186 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.814 0.186 0.000
R25 Abnormal involuntary movements
0.813 0.187 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.813 0.187 0.000
M79.60 Pain in limb (Multiple sites)
0.813 0.187 0.000
Y84.0 Cardiac catheterisation
0.810 0.190 0.000
J39 Other diseases of upper respiratory tract
0.807 0.193 0.000
G90-G99 Other disorders of the nervous system
0.807 0.193 0.000
T93 Sequelae of injuries of lower limb
0.807 0.193 0.000
T91 Sequelae of injuries of neck and trunk
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.804 0.195 0.000
S40-S49 Injuries to the shoulder and upper arm
0.804 0.196 0.000
J18 Pneumonia, organism unspecified
0.802 0.198 0.000
K81 Cholecystitis
0.802 0.198 0.000
A49 Bacterial infection of unspecified site
0.802 0.198 0.000
K86.8 Other specified diseases of pancreas
0.801 0.199 0.000
K65-K67 Diseases of peritoneum
0.801 0.199 0.000
Y40 Systemic antibiotics
0.800 0.200 0.000
K86.1 Other chronic pancreatitis
0.798 0.202 0.000
G47.3 Sleep apnoea
0.796 0.204 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.796 0.204 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.794 0.206 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.794 0.206 0.000
X50-X57 Overexertion, travel and privation
0.794 0.206 0.000
K80.4 Calculus of bile duct with cholecystitis
0.792 0.208 0.000
E70-E90 Metabolic disorders
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
B99-B99 Other infectious diseases
0.788 0.212 0.000
W19.9 Unspecified place
0.786 0.214 0.000
R47-R49 Symptoms and signs involving speech and voice
0.786 0.214 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.784 0.216 0.000
K14 Diseases of tongue
0.784 0.216 0.000
R10 Abdominal and pelvic pain
0.783 0.217 0.000
S00.8 Superficial injury of other parts of head
0.783 0.217 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
H65-H75 Diseases of middle ear and mastoid
0.781 0.219 0.000
J90 Pleural effusion, not elsewhere classified
0.779 0.221 0.000
M75.4 Impingement syndrome of shoulder
0.779 0.221 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.777 0.223 0.000
K90-K93 Other diseases of the digestive system
0.776 0.224 0.000
G82 Paraplegia and tetraplegia
0.775 0.225 0.000
R45 Symptoms and signs involving emotional state
0.774 0.226 0.000
M79.8 Other specified soft tissue disorders
0.774 0.226 0.000
Chapter V Mental and behavioural disorders
0.773 0.227 0.000
M79.63 Pain in limb (Forearm)
0.773 0.227 0.000
G44 Other headache syndromes
0.772 0.228 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.772 0.228 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.768 0.232 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.767 0.233 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.766 0.234 0.000
M20-M25 Other joint disorders
0.765 0.235 0.000
K86.9 Disease of pancreas, unspecified
0.765 0.235 0.000
R02 Gangrene, not elsewhere classified
0.764 0.236 0.000
M79.64 Pain in limb (Hand)
0.763 0.237 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.762 0.237 0.000
K13 Other diseases of lip and oral mucosa
0.762 0.238 0.000
M71 Other bursopathies
0.762 0.238 0.000
J35 Chronic diseases of tonsils and adenoids
0.762 0.238 0.000
R10.3 Pain localised to other parts of lower abdomen
0.760 0.240 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.759 0.241 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.759 0.241 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.758 0.242 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.758 0.242 0.000
J32 Chronic sinusitis
0.757 0.242 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.757 0.243 0.000
B37.8 Candidiasis of other sites
0.757 0.243 0.000
L20-L30 Dermatitis and eczema
0.756 0.244 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.754 0.246 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.752 0.248 0.000
J86 Pyothorax
0.752 0.248 0.000
M91-M94 Chondropathies
0.751 0.249 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.750 0.250 0.000
M77 Other enthesopathies
0.748 0.252 0.000
H61 Other disorders of external ear
0.748 0.252 0.000
G62.9 Polyneuropathy, unspecified
0.748 0.252 0.000
R42 Dizziness and giddiness
0.747 0.253 0.000
M72 Fibroblastic disorders
0.746 0.254 0.000
T79-T79 Certain early complications of trauma
0.746 0.254 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.746 0.254 0.000
T85.2 Mechanical complication of intraocular lens
0.745 0.255 0.000
M75.9 Shoulder lesion, unspecified
0.744 0.256 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.744 0.256 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.744 0.256 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.743 0.257 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.742 0.258 0.000
T78.4 Allergy, unspecified
0.741 0.258 0.000
K86.2 Cyst of pancreas
0.741 0.259 0.000
M75.1 Rotator cuff syndrome
0.741 0.259 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.740 0.260 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.740 0.260 0.000
M79.69 Pain in limb (Site unspecified)
0.739 0.261 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.738 0.262 0.000
J18.1 Lobar pneumonia, unspecified
0.737 0.263 0.000
M75.5 Bursitis of shoulder
0.737 0.263 0.000
G83 Other paralytic syndromes
0.735 0.265 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.734 0.265 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.734 0.265 0.000
R10.2 Pelvic and perineal pain
0.734 0.266 0.000
S02 Fracture of skull and facial bones
0.734 0.266 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.734 0.266 0.000
B44 Aspergillosis
0.733 0.267 0.000
G70-G73 Diseases of myoneural junction and muscle
0.732 0.268 0.000
S01.5 Open wound of lip and oral cavity
0.732 0.268 0.000
K08 Other disorders of teeth and supporting structures
0.731 0.268 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.731 0.269 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.730 0.270 0.000
M40-M43 Deforming dorsopathies
0.729 0.270 0.000
M79.7 Fibromyalgia
0.727 0.273 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.727 0.273 0.000
M75.2 Bicipital tendinitis
0.726 0.273 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.726 0.274 0.000
R11 Nausea and vomiting
0.725 0.275 0.000
K80.8 Other cholelithiasis
0.725 0.275 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.724 0.276 0.000
T90 Sequelae of injuries of head
0.723 0.277 0.000
T92 Sequelae of injuries of upper limb
0.723 0.277 0.000
B37.3 Candidiasis of vulva and vagina
0.723 0.277 0.000
A41 Other septicaemia
0.722 0.278 0.000
K01 Embedded and impacted teeth
0.722 0.278 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.720 0.280 0.000
K11 Diseases of salivary glands
0.720 0.280 0.000
J38.7 Other diseases of larynx
0.719 0.281 0.000
H90-H95 Other disorders of ear
0.719 0.281 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.716 0.284 0.000
R06.1 Stridor
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.715 0.285 0.000
J42 Unspecified chronic bronchitis
0.714 0.286 0.000
K10 Other diseases of jaws
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.713 0.287 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.713 0.287 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.712 0.288 0.000
K05 Gingivitis and periodontal diseases
0.712 0.288 0.000
H80 Otosclerosis
0.712 0.288 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.711 0.289 0.000
M50-M54 Other dorsopathies
0.711 0.289 0.000
R07.1 Chest pain on breathing
0.711 0.289 0.000
M65-M68 Disorders of synovium and tendon
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.710 0.290 0.000
Y43 Primarily systemic agents
0.710 0.290 0.000
M79.9 Soft tissue disorder, unspecified
0.709 0.290 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.709 0.290 0.000
M79.3 Panniculitis, unspecified
0.709 0.290 0.000
M79.2 Neuralgia and neuritis, unspecified
0.709 0.290 0.000
M79.1 Myalgia
0.709 0.290 0.000
A49.0 Staphylococcal infection, unspecified
0.709 0.291 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.709 0.291 0.000
M79.5 Residual foreign body in soft tissue
0.709 0.291 0.000
S01.8 Open wound of other parts of head
0.709 0.291 0.000
K80.3 Calculus of bile duct with cholangitis
0.708 0.292 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.708 0.292 0.000
K85.1 Biliary acute pancreatitis
0.708 0.292 0.000
J37 Chronic laryngitis and laryngotracheitis
0.707 0.293 0.000
J38.1 Polyp of vocal cord and larynx
0.706 0.294 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.706 0.294 0.000
K09 Cysts of oral region, not elsewhere classified
0.705 0.295 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.705 0.295 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
S32 Fracture of lumbar spine and pelvis
0.704 0.295 0.000
M25 Other joint disorders, not elsewhere classified
0.704 0.296 0.000
M79.68 Pain in limb (Other)
0.704 0.296 0.000
M79.61 Pain in limb (Shoulder region)
0.704 0.296 0.000
S20 Superficial injury of thorax
0.704 0.296 0.000
M79.0 Rheumatism, unspecified
0.704 0.296 0.000
K70-K77 Diseases of liver
0.702 0.298 0.000
J47 Bronchiectasis
0.702 0.298 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.701 0.298 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.701 0.299 0.000
J91 Pleural effusion in conditions classified elsewhere
0.701 0.299 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.700 0.299 0.000
M75.8 Other shoulder lesions
0.700 0.300 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.700 0.300 0.000
Y84.9 Medical procedure, unspecified
0.699 0.301 0.000
Y84.7 Blood-sampling
0.699 0.301 0.000
Y84.5 Insertion of gastric or duodenal sound
0.699 0.301 0.000
Y84.4 Aspiration of fluid
0.699 0.301 0.000
Y84.3 Shock therapy
0.699 0.301 0.000
J20-J22 Other acute lower respiratory infections
0.699 0.301 0.000
W20-W49 Exposure to inanimate mechanical forces
0.699 0.301 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.697 0.303 0.000
E20-E35 Disorders of other endocrine glands
0.697 0.303 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.696 0.304 0.000
E89.0 Postprocedural hypothyroidism
0.696 0.304 0.000
K85.9 Acute pancreatitis, unspecified
0.695 0.304 0.000
J43 Emphysema
0.695 0.305 0.000
S82.4 Fracture of fibula alone
0.694 0.305 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.694 0.306 0.000
R40 Somnolence, stupor and coma
0.694 0.306 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.692 0.308 0.000
R06.8 Other and unspecified abnormalities of breathing
0.691 0.309 0.000
J45 Asthma
0.689 0.311 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.688 0.312 0.000
B48 Other mycoses, not elsewhere classified
0.688 0.312 0.000
B47 Mycetoma
0.688 0.312 0.000
B46 Zygomycosis
0.688 0.312 0.000
B45 Cryptococcosis
0.688 0.312 0.000
B43 Chromomycosis and phaeomycotic abscess
0.688 0.312 0.000
B42 Sporotrichosis
0.688 0.312 0.000
B41 Paracoccidioidomycosis
0.688 0.312 0.000
B40 Blastomycosis
0.688 0.312 0.000
B39 Histoplasmosis
0.688 0.312 0.000
B38 Coccidioidomycosis
0.688 0.312 0.000
B36 Other superficial mycoses
0.688 0.312 0.000
B35 Dermatophytosis
0.688 0.312 0.000
B49 Unspecified mycosis
0.688 0.312 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.688 0.312 0.000
G41.9 Status epilepticus, unspecified
0.688 0.312 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.688 0.312 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.687 0.312 0.000
J34.2 Deviated nasal septum
0.687 0.313 0.000
M79.67 Pain in limb (Ankle and foot)
0.687 0.313 0.000
T78.2 Anaphylactic shock, unspecified
0.687 0.313 0.000
E87.2 Acidosis
0.686 0.314 0.000
G62.8 Other specified polyneuropathies
0.686 0.314 0.000
R26.3 Immobility
0.686 0.314 0.000
B15-B19 Viral hepatitis
0.684 0.316 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.684 0.316 0.000
M80-M85 Disorders of bone density and structure
0.683 0.316 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
K83.0 Cholangitis
0.682 0.318 0.000
G95 Other diseases of spinal cord
0.681 0.319 0.000
T39.1 4-Aminophenol derivatives
0.681 0.319 0.000
G40.8 Other epilepsy
0.680 0.320 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.680 0.320 0.000
G40.5 Special epileptic syndromes
0.680 0.320 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.680 0.320 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.680 0.320 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.680 0.320 0.000
J95-J99 Other diseases of the respiratory system
0.680 0.320 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.678 0.322 0.000
J86.9 Pyothorax without fistula
0.678 0.322 0.000
Q60-Q64 Congenital malformations of the urinary system
0.678 0.322 0.000
V20-V29 Motorcycle rider injured in transport accident
0.677 0.323 0.000
S08 Traumatic amputation of part of head
0.675 0.324 0.000
S07 Crushing injury of head
0.675 0.324 0.000
S05 Injury of eye and orbit
0.675 0.324 0.000
S04 Injury of cranial nerves
0.675 0.324 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.675 0.324 0.000
J41 Simple and mucopurulent chronic bronchitis
0.675 0.325 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.675 0.325 0.000
R27 Other lack of coordination
0.674 0.326 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.673 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.673 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
T42.4 Benzodiazepines
0.673 0.327 0.000
J30.1 Allergic rhinitis due to pollen
0.672 0.327 0.000
H81 Disorders of vestibular function
0.671 0.329 0.000
V10-V19 Pedal cyclist injured in transport accident
0.671 0.329 0.000
T93.1 Sequelae of fracture of femur
0.671 0.329 0.000
J38.0 Paralysis of vocal cords and larynx
0.670 0.329 0.000
Y40.0 Penicillins
0.670 0.330 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.670 0.330 0.000
H60 Otitis externa
0.670 0.330 0.000
G82.2 Paraplegia, unspecified
0.668 0.332 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.667 0.332 0.000
Y88 Sequelae of surgical and medical care as external cause
0.667 0.332 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.667 0.333 0.000
S82.1 Fracture of upper end of tibia
0.667 0.333 0.000
B37.7 Candidal septicaemia
0.666 0.334 0.000
B37.6 Candidal endocarditis
0.666 0.334 0.000
B37.5 Candidal meningitis
0.666 0.334 0.000
B37.4 Candidiasis of other urogenital sites
0.666 0.334 0.000
B37.2 Candidiasis of skin and nail
0.666 0.334 0.000
B37.1 Pulmonary candidiasis
0.666 0.334 0.000
S82.81 Fractures of other parts of lower leg (open)
0.666 0.334 0.000
G47.8 Other sleep disorders
0.666 0.334 0.000
G47.4 Narcolepsy and cataplexy
0.666 0.334 0.000
G47.2 Disorders of the sleep-wake schedule
0.666 0.334 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.666 0.334 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.665 0.335 0.000
Q50-Q56 Congenital malformations of genital organs
0.665 0.335 0.000
S91 Open wound of ankle and foot
0.664 0.336 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.664 0.336 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.664 0.336 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.664 0.336 0.000
S01.2 Open wound of nose
0.664 0.336 0.000
K50-K52 Noninfective enteritis and colitis
0.664 0.336 0.000
K03 Other diseases of hard tissues of teeth
0.663 0.337 0.000
K00 Disorders of tooth development and eruption
0.663 0.337 0.000
Y52 Agents primarily affecting the cardiovascular system
0.663 0.337 0.000
J30.4 Allergic rhinitis, unspecified
0.662 0.338 0.000
J39.2 Other diseases of pharynx
0.662 0.338 0.000
M22 Disorders of patella
0.662 0.338 0.000
S01.9 Open wound of head, part unspecified
0.661 0.339 0.000
Y40.8 Other systemic antibiotics
0.661 0.339 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.661 0.339 0.000
G24 Dystonia
0.661 0.339 0.000
G23 Other degenerative diseases of basal ganglia
0.661 0.339 0.000
G21 Secondary Parkinsonism
0.661 0.339 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.661 0.339 0.000
G22 Parkinsonism in diseases classified elsewhere
0.661 0.339 0.000
J38.4 Oedema of larynx
0.661 0.339 0.000
K14.9 Disease of tongue, unspecified
0.660 0.340 0.000
S82.3 Fracture of lower end of tibia
0.660 0.340 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.659 0.341 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.659 0.341 0.000
R45.8 Other symptoms and signs involving emotional state
0.658 0.342 0.000
Y57 Other and unspecified drugs and medicaments
0.657 0.343 0.000
R07.0 Pain in throat
0.656 0.343 0.000
H61.0 Perichondritis of external ear
0.656 0.344 0.000
Y85 Sequelae of transport accidents
0.655 0.344 0.000
M25.5 Pain in joint
0.655 0.345 0.000
J10 Influenza due to identified influenza virus
0.655 0.345 0.000
G25 Other extrapyramidal and movement disorders
0.654 0.345 0.000
J38.3 Other diseases of vocal cords
0.654 0.346 0.000
T75 Effects of other external causes
0.653 0.346 0.000
T74 Maltreatment syndromes
0.653 0.346 0.000
T73 Effects of other deprivation
0.653 0.346 0.000
T70 Effects of air pressure and water pressure
0.653 0.346 0.000
T69 Other effects of reduced temperature
0.653 0.346 0.000
T67 Effects of heat and light
0.653 0.346 0.000
T71 Asphyxiation
0.653 0.346 0.000
T68 Hypothermia
0.653 0.346 0.000
T66 Unspecified effects of radiation
0.653 0.346 0.000
Y59 Other and unspecified vaccines and biological substances
0.653 0.347 0.000
Y58 Bacterial vaccines
0.653 0.347 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.653 0.347 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.653 0.347 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.653 0.347 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.653 0.347 0.000
Y48 Anaesthetics and therapeutic gases
0.653 0.347 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.653 0.347 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.653 0.347 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.652 0.348 0.000
W18 Other fall on same level
0.652 0.348 0.000
W17 Other fall from one level to another
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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