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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74683406
log Bayes Factor = 6.02368
Chromosome 1   position 11,859,636  (GRCh37) Explore rs74683406 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.269 0.731
I12 Hypertensive renal disease
0.000 0.366 0.634
I12.0 Hypertensive renal disease with renal failure
0.000 0.419 0.581
I13 Hypertensive heart and renal disease
0.000 0.476 0.524
I15 Secondary hypertension
0.000 0.479 0.521
I11 Hypertensive heart disease
0.000 0.519 0.481
I12.9 Hypertensive renal disease without renal failure
0.000 0.598 0.402
I60-I69 Cerebrovascular diseases
0.000 0.601 0.399
Chapter IX Diseases of the circulatory system
0.000 0.605 0.395
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.618 0.382
I20-I25 Ischaemic heart diseases
0.000 0.620 0.380
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.624 0.376
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.624 0.376
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.624 0.376
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.624 0.376
I15.9 Seconday hypertension, unspecified
0.000 0.626 0.374
I15.8 Other secondary hypertension
0.000 0.626 0.374
I15.2 Hypertension secondary to endocrine disorders
0.000 0.626 0.374
I15.0 Renovascular hypertension
0.000 0.626 0.374
I15.1 Hypertension secondary to other renal disorders
0.000 0.629 0.371
I65.2 Occlusion and stenosis of carotid artery
0.000 0.630 0.370
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.639 0.361
I63 Cerebral infarction
0.000 0.643 0.357
I25 Chronic ischaemic heart disease
0.000 0.647 0.353
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.655 0.345
I25.5 Ischaemic cardiomyopathy
0.000 0.671 0.329
I21 Acute myocardial infarction
0.000 0.672 0.328
I21.9 Acute myocardial infarction, unspecified
0.000 0.673 0.327
I61 Intracerebral haemorrhage
0.000 0.679 0.321
I60 Subarachnoid haemorrhage
0.000 0.685 0.315
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.690 0.310
I63.8 Other cerebral infarction
0.000 0.696 0.304
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.696 0.304
I22 Subsequent myocardial infarction
0.000 0.697 0.303
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.698 0.302
I67 Other cerebrovascular diseases
0.000 0.699 0.301
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.701 0.299
I69 Sequelae of cerebrovascular disease
0.000 0.701 0.299
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.702 0.298
I25.2 Old myocardial infarction
0.000 0.711 0.289
I20 Angina pectoris
0.000 0.713 0.287
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.714 0.286
I00-I02 Acute rheumatic fever
0.000 0.717 0.283
I67.8 Other specified cerebrovascular diseases
0.000 0.726 0.274
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.726 0.274
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.726 0.274
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.726 0.274
I65.1 Occlusion and stenosis of basilar artery
0.000 0.726 0.274
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.726 0.274
I23 Certain current complications following acute myocardial infarction
0.000 0.727 0.273
I20.9 Angina pectoris, unspecified
0.000 0.733 0.267
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.739 0.261
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.741 0.259
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.743 0.257
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.744 0.256
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.744 0.256
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.744 0.256
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.744 0.256
I25.6 Silent myocardial ischaemia
0.000 0.747 0.253
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.747 0.253
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.747 0.253
I62 Other nontraumatic intracranial haemorrhage
0.000 0.749 0.251
I25.4 Coronary artery aneurysm
0.000 0.751 0.249
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.755 0.245
I24 Other acute ischaemic heart diseases
0.000 0.759 0.241
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.762 0.238
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.762 0.238
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.764 0.236
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.765 0.235
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.765 0.235
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.767 0.233
I61.8 Other intracerebral haemorrhage
0.000 0.770 0.230
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.770 0.230
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.770 0.230
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.770 0.230
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.770 0.230
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.770 0.230
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.772 0.228
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.774 0.226
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.774 0.226
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.774 0.226
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.774 0.226
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.774 0.226
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.774 0.226
I67.9 Cerebrovascular disease, unspecified
0.000 0.775 0.225
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.776 0.224
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.781 0.219
I63.9 Cerebral infarction, unspecified
0.000 0.782 0.218
I22.8 Subsequent myocardial infarction of other sites
0.000 0.783 0.217
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.784 0.216
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.784 0.216
I67.5 Moyamoya disease
0.000 0.784 0.216
I67.4 Hypertensive encephalopathy
0.000 0.784 0.216
I67.3 Progressive vascular leukoencephalopathy
0.000 0.784 0.216
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.784 0.216
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.785 0.214
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.786 0.214
I20.1 Angina pectoris with documented spasm
0.000 0.790 0.210
I60.8 Other subarachnoid haemorrhage
0.000 0.792 0.208
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.795 0.205
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.795 0.205
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.795 0.205
I68.0 Cerebral amyloid angiopathy
0.000 0.795 0.205
I25.3 Aneurysm of heart
0.000 0.795 0.205
I02 Rheumatic chorea
0.000 0.797 0.203
I01 Rheumatic fever with heart involvement
0.000 0.797 0.203
I00 Rheumatic fever without mention of heart involvement
0.000 0.797 0.203
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.800 0.200
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.800 0.199
I23.8 Other current complications following acute myocardial infarction
0.000 0.804 0.196
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.804 0.196
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.804 0.196
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.804 0.196
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.804 0.196
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.804 0.196
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.804 0.196
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.804 0.196
I05-I09 Chronic rheumatic heart diseases
0.000 0.807 0.192
I20.8 Other forms of angina pectoris
0.000 0.809 0.191
I69.3 Sequelae of cerebral infarction
0.000 0.815 0.184
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.817 0.183
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.818 0.181
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.818 0.181
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.818 0.181
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.818 0.181
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.818 0.181
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.818 0.181
I62.1 Nontraumatic extradural haemorrhage
0.000 0.820 0.180
I67.2 Cerebral atherosclerosis
0.000 0.826 0.173
I21.4 Acute subendocardial myocardial infarction
0.000 0.827 0.173
I24.1 Dressler's syndrome
0.000 0.827 0.173
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.833 0.167
I24.8 Other forms of acute ischaemic heart disease
0.000 0.833 0.167
I08 Multiple valve diseases
0.000 0.839 0.160
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.842 0.157
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.843 0.157
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.852 0.148
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.853 0.146
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.854 0.146
I01.8 Other acute rheumatic heart disease
0.000 0.854 0.146
I01.2 Acute rheumatic myocarditis
0.000 0.854 0.146
I01.1 Acute rheumatic endocarditis
0.000 0.854 0.146
I01.0 Acute rheumatic pericarditis
0.000 0.854 0.146
I02.9 Rheumatic chorea without heart involvement
0.000 0.854 0.146
I02.0 Rheumatic chorea with heart involvement
0.000 0.854 0.146
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.855 0.145
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.859 0.141
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.860 0.140
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.861 0.138
I06 Rheumatic aortic valve diseases
0.000 0.862 0.138
I67.1 Cerebral aneurysm, nonruptured
0.000 0.862 0.137
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.872 0.128
I74 Arterial embolism and thrombosis
0.000 0.874 0.126
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.878 0.122
I09 Other rheumatic heart diseases
0.001 0.881 0.119
I08.9 Multiple valve disease, unspecified
0.000 0.885 0.115
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.891 0.109
I77 Other disorders of arteries and arterioles
0.000 0.891 0.109
I25.1 Atherosclerotic heart disease
0.000 0.896 0.104
I07 Rheumatic tricuspid valve diseases
0.001 0.896 0.103
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.898 0.102
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.898 0.102
I08.8 Other multiple valve diseases
0.000 0.899 0.100
I28 Other diseases of pulmonary vessels
0.001 0.900 0.099
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.900 0.099
I06.8 Other rheumatic aortic valve diseases
0.000 0.900 0.099
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.900 0.099
I06.1 Rheumatic aortic insufficiency
0.000 0.900 0.099
I06.0 Rheumatic aortic stenosis
0.000 0.900 0.099
L90.5 Scar conditions and fibrosis of skin
0.000 0.902 0.098
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.905 0.095
I77.1 Stricture of artery
0.000 0.905 0.095
I70 Atherosclerosis
0.000 0.907 0.092
I72 Other aneurysm
0.000 0.909 0.091
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.909 0.091
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.909 0.091
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.909 0.091
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.909 0.091
L90 Atrophic disorders of skin
0.000 0.910 0.090
I74.5 Embolism and thrombosis of iliac artery
0.000 0.911 0.089
L90.0 Lichen sclerosus et atrophicus
0.000 0.912 0.088
I74.8 Embolism and thrombosis of other arteries
0.000 0.914 0.086
I09.8 Other specified rheumatic heart diseases
0.001 0.914 0.085
I09.2 Chronic rheumatic pericarditis
0.001 0.914 0.085
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.914 0.085
I09.0 Rheumatic myocarditis
0.001 0.914 0.085
I95-I99 Other and unspecified disorders of the circulatory system
0.001 0.915 0.084
I05 Rheumatic mitral valve diseases
0.001 0.918 0.081
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.919 0.081
I73 Other peripheral vascular diseases
0.000 0.919 0.081
I82 Other venous embolism and thrombosis
0.000 0.920 0.080
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.921 0.079
I77.5 Necrosis of artery
0.000 0.922 0.078
I77.4 Coeliac artery compression syndrome
0.000 0.922 0.078
I77.3 Arterial fibromuscular dysplasia
0.000 0.922 0.078
I77.2 Rupture of artery
0.000 0.922 0.078
I77.0 Arteriovenous fistula, acquired
0.000 0.922 0.078
I07.9 Tricuspid valve disease, unspecified
0.001 0.925 0.074
I07.8 Other tricuspid valve diseases
0.001 0.925 0.074
I07.2 Tricuspid stenosis with insufficiency
0.001 0.925 0.074
I07.0 Tricuspid stenosis
0.001 0.925 0.074
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.926 0.073
I79.1 Aortitis in diseases classified elsewhere
0.000 0.926 0.073
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.926 0.073
I77.6 Arteritis, unspecified
0.000 0.928 0.072
I08.0 Disorders of both mitral and aortic valves
0.000 0.928 0.072
I89.0 Lymphoedema, not elsewhere classified
0.000 0.928 0.072
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.928 0.072
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.928 0.071
I28.8 Other specified diseases of pulmonary vessels
0.001 0.928 0.071
I28.1 Aneurysm of pulmonary artery
0.001 0.928 0.071
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.928 0.071
I85 Oesophageal varices
0.000 0.930 0.070
I88 Nonspecific lymphadenitis
0.000 0.931 0.069
I87 Other disorders of veins
0.000 0.931 0.069
I73.9 Peripheral vascular disease, unspecified
0.000 0.932 0.068
I70.0 Atherosclerosis of aorta
0.000 0.933 0.067
I09.9 Rheumatic heart disease, unspecified
0.001 0.933 0.066
I72.8 Aneurysm of other specified arteries
0.000 0.933 0.067
I70.9 Generalised and unspecified atherosclerosis
0.000 0.933 0.066
I70.8 Atherosclerosis of other arteries
0.000 0.933 0.066
I72.3 Aneurysm of iliac artery
0.000 0.934 0.066
I72.9 Aneurysm of unspecified site
0.000 0.934 0.065
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.934 0.065
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.934 0.065
I72.2 Aneurysm of renal artery
0.000 0.934 0.065
I72.1 Aneurysm of artery of upper extremity
0.000 0.934 0.065
I82.8 Embolism and thrombosis of other specified veins
0.000 0.935 0.065
L90.9 Atrophic disorder of skin, unspecified
0.000 0.936 0.064
L90.8 Other atrophic disorders of skin
0.000 0.936 0.064
L90.6 Striae atrophicae
0.000 0.936 0.064
L90.4 Acrodermatitis chronica atrophicans
0.000 0.936 0.064
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.936 0.064
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.936 0.064
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.936 0.064
I71 Aortic aneurysm and dissection
0.000 0.936 0.064
I78 Diseases of capillaries
0.000 0.937 0.063
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.937 0.063
I70.1 Atherosclerosis of renal artery
0.000 0.938 0.062
I77.8 Other specified disorders of arteries and arterioles
0.000 0.938 0.061
I80 Phlebitis and thrombophlebitis
0.000 0.939 0.061
I89.1 Lymphangitis
0.000 0.940 0.060
I26 Pulmonary embolism
0.001 0.940 0.059
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.941 0.059
I72.0 Aneurysm of carotid artery
0.000 0.941 0.059
I05.8 Other mitral valve diseases
0.001 0.941 0.058
I72.4 Aneurysm of artery of lower extremity
0.000 0.941 0.058
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.942 0.058
I81 Portal vein thrombosis
0.000 0.942 0.058
I82.3 Embolism and thrombosis of renal vein
0.000 0.943 0.057
I82.2 Embolism and thrombosis of vena cava
0.000 0.943 0.057
I82.1 Thrombophlebitis migrans
0.000 0.943 0.057
I82.0 Budd-Chiari syndrome
0.000 0.943 0.057
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.943 0.057
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.944 0.056
I05.2 Mitral stenosis with insufficiency
0.001 0.948 0.052
I86 Varicose veins of other sites
0.000 0.948 0.052
I85.9 Oesophageal varices without bleeding
0.000 0.948 0.052
I87.1 Compression of vein
0.000 0.948 0.051
I05.9 Mitral valve disease, unspecified
0.001 0.948 0.051
I05.1 Rheumatic mitral insufficiency
0.001 0.948 0.051
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.949 0.051
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.949 0.051
I99 Other and unspecified disorders of circulatory system
0.001 0.949 0.050
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.949 0.051
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.950 0.050
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.950 0.050
I73.8 Other specified peripheral vascular diseases
0.000 0.950 0.050
I85.0 Oesophageal varices with bleeding
0.000 0.950 0.050
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.950 0.049
I88.8 Other nonspecific lymphadenitis
0.000 0.950 0.049
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.950 0.049
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.950 0.049
I87.9 Disorder of vein, unspecified
0.000 0.951 0.049
I87.0 Postphlebitic syndrome
0.000 0.951 0.049
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.951 0.049
I20.0 Unstable angina
0.000 0.951 0.049
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.951 0.048
I27 Other pulmonary heart diseases
0.001 0.952 0.047
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.952 0.047
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.952 0.048
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.952 0.048
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.952 0.048
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.952 0.048
I71.0 Dissection of aorta [any part]
0.000 0.952 0.048
I05.0 Mitral stenosis
0.001 0.952 0.047
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.954 0.046
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.954 0.046
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.954 0.046
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.954 0.046
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.954 0.046
I87.8 Other specified disorders of veins
0.000 0.954 0.046
I78.9 Disease of capillaries, unspecified
0.000 0.954 0.045
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.955 0.045
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.956 0.044
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.957 0.043
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.957 0.043
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.957 0.042
I21.0 Acute transmural myocardial infarction of anterior wall
0.001 0.957 0.042
I78.8 Other diseases of capillaries
0.000 0.958 0.042
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.959 0.041
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.959 0.040
I07.1 Tricuspid insufficiency
0.001 0.960 0.039
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.962 0.037
I86.3 Vulval varices
0.000 0.963 0.037
I86.2 Pelvic varices
0.000 0.963 0.037
I86.0 Sublingual varices
0.000 0.963 0.037
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.963 0.037
I97.1 Other functional disturbances following cardiac surgery
0.001 0.963 0.037
I97.0 Postcardiotomy syndrome
0.001 0.963 0.037
I86.8 Varicose veins of other specified sites
0.000 0.963 0.037
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.964 0.036
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.965 0.035
I27.8 Other specified pulmonary heart diseases
0.001 0.965 0.034
I27.1 Kyphoscoliotic heart disease
0.001 0.965 0.034
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.965 0.034
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.965 0.034
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.965 0.034
I98.0 Cardiovascular syphilis
0.001 0.965 0.034
I86.1 Scrotal varices
0.000 0.967 0.033
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.967 0.032
I97.2 Postmastectomy lymphoedema syndrome
0.001 0.967 0.032
L85 Other epidermal thickening
0.000 0.967 0.033
L81 Other disorders of pigmentation
0.000 0.968 0.032
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.969 0.031
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.970 0.030
L85.9 Epidermal thickening, unspecified
0.000 0.970 0.030
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.971 0.029
L84 Corns and callosities
0.000 0.971 0.029
I86.4 Gastric varices
0.000 0.972 0.028
L81.9 Disorder of pigmentation, unspecified
0.000 0.973 0.027
I27.2 Other secondary pulmonary hypertension
0.001 0.973 0.026
L93 Lupus erythematosus
0.000 0.973 0.026
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.974 0.026
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.974 0.026
L87 Transepidermal elimination disorders
0.000 0.974 0.026
L88 Pyoderma gangrenosum
0.000 0.974 0.026
L86 Keratoderma in diseases classified elsewhere
0.000 0.974 0.026
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.974 0.026
I83 Varicose veins of lower extremities
0.000 0.974 0.026
L80 Vitiligo
0.000 0.974 0.025
I27.0 Primary pulmonary hypertension
0.001 0.974 0.025
L81.4 Other melanin hyperpigmentation
0.000 0.975 0.025
L85.8 Other specified epidermal thickening
0.000 0.975 0.025
I78.1 Naevus, nonneoplastic
0.000 0.975 0.025
L94 Other localised connective tissue disorders
0.000 0.975 0.025
L83 Acanthosis nigricans
0.000 0.975 0.025
I27.9 Pulmonary heart disease, unspecified
0.001 0.976 0.023
L85.3 Xerosis cutis
0.000 0.976 0.024
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.976 0.024
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.976 0.024
L85.0 Acquired ichthyosis
0.000 0.976 0.024
L81.8 Other specified disorders of pigmentation
0.000 0.977 0.023
L81.7 Pigmented purpuric dermatosis
0.000 0.977 0.023
L81.6 Other disorders of diminished melanin formation
0.000 0.977 0.023
L81.5 Leukoderma, not elsewhere classified
0.000 0.977 0.023
L81.3 Cafe au lait spots
0.000 0.977 0.023
L81.2 Freckles
0.000 0.977 0.023
L81.1 Chloasma
0.000 0.977 0.023
L81.0 Postinflammatory hyperpigmentation
0.000 0.977 0.023
I73.0 Raynaud's syndrome
0.000 0.977 0.023
L92.0 Granuloma annulare
0.000 0.977 0.022
L89 Decubitus ulcer
0.000 0.978 0.022
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.978 0.022
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.978 0.022
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.978 0.022
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.978 0.022
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.978 0.021
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.980 0.019
L91 Hypertrophic disorders of skin
0.000 0.981 0.019
L93.0 Discoid lupus erythematosus
0.000 0.981 0.019
L93.2 Other local lupus erythematosus
0.000 0.981 0.019
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.981 0.019
L87.9 Transepidermal elimination disorder, unspecified
0.000 0.981 0.019
L87.8 Other transepidermal elimination disorders
0.000 0.981 0.019
L87.2 Elastosis perforans serpiginosa
0.000 0.981 0.019
L87.1 Reactive perforating collagenosis
0.000 0.981 0.019
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]
0.000 0.981 0.019
L95.9 Vasculitis limited to skin, unspecified
0.000 0.981 0.019
L95.8 Other vasculitis limited to skin
0.000 0.981 0.019
L95.1 Erythema elevatum diutinum
0.000 0.981 0.019
L95.0 Livedoid vasculitis
0.000 0.981 0.019
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.981 0.019
L99.0 Amyloidosis of skin
0.000 0.981 0.019
R53 Malaise and fatigue
0.000 0.981 0.019
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.981 0.019
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.982 0.018
L94.9 Localised connective tissue disorder, unspecified
0.000 0.982 0.018
L94.8 Other specified localised connective tissue disorders
0.000 0.982 0.018
L94.6 Ainhum
0.000 0.982 0.018
L94.5 Poikiloderma vasculare atrophicans
0.000 0.982 0.018
L94.4 Gottron's papules
0.000 0.982 0.018
L94.3 Sclerodactyly
0.000 0.982 0.018
L94.1 Linear scleroderma
0.000 0.982 0.018
L94.0 Localised scleroderma [morphea]
0.000 0.982 0.018
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.982 0.017
L89.2 Stage III decubitus ulcer
0.000 0.983 0.017
L94.2 Calcinosis cutis
0.000 0.983 0.017
O80.0 Spontaneous vertex delivery
0.017 0.983 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.983 0.017
I30-I52 Other forms of heart disease
0.000 0.983 0.017
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.984 0.016
I34.0 Mitral (valve) insufficiency
0.000 0.984 0.016
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.984 0.016
I34.1 Mitral (valve) prolapse
0.000 0.985 0.015
L89.1 Stage II decubitus ulcer
0.000 0.985 0.014
L91.0 Keloid scar
0.000 0.986 0.014
L91.9 Hypertrophic disorder of skin, unspecified
0.000 0.986 0.014
I46 Cardiac arrest
0.000 0.986 0.014
L89.3 Stage IV decubitus ulcer
0.000 0.986 0.014
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.987 0.013
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.987 0.013
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.987 0.013
L98.5 Mucinosis of skin
0.000 0.987 0.013
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.987 0.013
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.000 0.987 0.013
L98.1 Factitial dermatitis
0.000 0.987 0.013
I46.9 Cardiac arrest, unspecified
0.000 0.987 0.013
I36 Nonrheumatic tricuspid valve disorders
0.000 0.987 0.013
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.987 0.013
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.987 0.013
I95 Hypotension
0.001 0.988 0.012
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.988 0.012
I38 Endocarditis, valve unspecified
0.000 0.988 0.012
I52 Other heart disorders in diseases classified elsewhere
0.000 0.988 0.012
I48 Atrial fibrillation and flutter
0.000 0.988 0.012
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.988 0.012
I41 Myocarditis in diseases classified elsewhere
0.000 0.988 0.012
I40 Acute myocarditis
0.000 0.988 0.012
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.988 0.012
I37 Pulmonary valve disorders
0.000 0.988 0.012
I32 Pericarditis in diseases classified elsewhere
0.000 0.988 0.012
S80 Superficial injury of lower leg
0.012 0.988 0.000
I51.7 Cardiomegaly
0.000 0.988 0.012
S52 Fracture of forearm
0.011 0.989 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.989 0.011
I33 Acute and subacute endocarditis
0.000 0.989 0.011
I51 Complications and ill-defined descriptions of heart disease
0.000 0.989 0.011
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.989 0.011
S52.6 Fracture of lower end of both ulna and radius
0.011 0.989 0.000
S80.9 Superficial injury of lower leg, unspecified
0.011 0.989 0.000
S80.0 Contusion of knee
0.011 0.989 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.989 0.010
I30 Acute pericarditis
0.000 0.990 0.010
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.990 0.010
S80-S89 Injuries to the knee and lower leg
0.010 0.990 0.000
I46.1 Sudden cardiac death, so described
0.000 0.990 0.010
S50-S59 Injuries to the elbow and forearm
0.010 0.990 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.010 0.990 0.000
S52.3 Fracture of shaft of radius
0.010 0.990 0.000
O80 Single spontaneous delivery
0.010 0.990 0.000
S80.8 Other superficial injuries of lower leg
0.010 0.990 0.000
S52.5 Fracture of lower end of radius
0.010 0.990 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.010 0.990 0.000
S56 Injury of muscle and tendon at forearm level
0.010 0.990 0.000
L98.0 Pyogenic granuloma
0.000 0.990 0.010
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.990 0.009
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.990 0.009
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.990 0.009
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.990 0.009
S52.30 Fracture of shaft of radius (closed)
0.009 0.991 0.000
E10.9 Without complications
0.000 0.991 0.009
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.009 0.991 0.000
I95.0 Idiopathic hypotension
0.001 0.991 0.009
S52.4 Fracture of shafts of both ulna and radius
0.009 0.991 0.000
I31 Other diseases of pericardium
0.000 0.991 0.009
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.009 0.991 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.991 0.009
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.991 0.009
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.991 0.009
I37.9 Pulmonary valve disorder, unspecified
0.000 0.991 0.009
I37.8 Other pulmonary valve disorders
0.000 0.991 0.009
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.991 0.009
I37.1 Pulmonary valve insufficiency
0.000 0.991 0.009
I37.0 Pulmonary valve stenosis
0.000 0.991 0.009
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.991 0.009
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.991 0.009
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.991 0.009
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.991 0.009
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.991 0.009
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.991 0.009
I40.9 Acute myocarditis, unspecified
0.000 0.991 0.009
I40.8 Other acute myocarditis
0.000 0.991 0.009
I40.1 Isolated myocarditis
0.000 0.991 0.009
I40.0 Infective myocarditis
0.000 0.991 0.009
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.991 0.009
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.991 0.009
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.991 0.009
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.991 0.009
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.991 0.009
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.991 0.009
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.991 0.009
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.991 0.009
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.991 0.009
I48.4 Atypical atrial flutter
0.000 0.991 0.009
I48.3 Typical atrial flutter
0.000 0.991 0.009
I48.2 Chronic atrial fibrillation
0.000 0.991 0.009
I48.1 Persistent atrial fibrillation
0.000 0.991 0.009
I48.0 Paroxysmal atrial fibrillation
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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