TreeWAS – Variant ID: rs74795342

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H33.0 Retinal detachment with retinal break	0.054	0.946	0.000
H33 Retinal detachments and breaks	0.032	0.968	0.000
H33.5 Other retinal detachments	0.025	0.975	0.000
H33.2 Serous retinal detachment	0.024	0.976	0.000
H33.4 Traction detachment of retina	0.023	0.977	0.000
H33.1 Retinoschisis and retinal cysts	0.023	0.977	0.000
H33.3 Retinal breaks without detachment	0.023	0.977	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.008	0.992	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.993	0.007
H30-H36 Disorders of choroid and retina	0.007	0.993	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.006	0.994	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.006	0.994	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.005	0.995	0.000
H31 Other disorders of choroid	0.005	0.995	0.000
H30 Chorioretinal inflammation	0.005	0.995	0.000
H36 Retinal disorders in diseases classified elsewhere	0.005	0.995	0.000
N76.4 Abscess of vulva	0.000	0.995	0.005
C85.7 Other specified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
C85.1 B-cell lymphoma, unspecified	0.005	0.995	0.000
N13 Obstructive and reflux uropathy	0.000	0.995	0.005
J33.9 Nasal polyp, unspecified	0.000	0.995	0.005
N76 Other inflammation of vagina and vulva	0.000	0.995	0.005
H34 Retinal vascular occlusions	0.004	0.995	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.996	0.004
N13.8 Other obstructive and reflux uropathy	0.000	0.996	0.004
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.004	0.996	0.000
C85.0 Lymphosarcoma	0.004	0.996	0.000
N13.4 Hydroureter	0.000	0.996	0.004
N13.3 Other and unspecified hydronephrosis	0.000	0.996	0.004
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.996	0.004
K43 Ventral hernia	0.000	0.996	0.004
H30.9 Chorioretinal inflammation, unspecified	0.004	0.996	0.000
H30.8 Other chorioretinal inflammations	0.004	0.996	0.000
H30.2 Posterior cyclitis	0.004	0.996	0.000
H30.1 Disseminated chorioretinal inflammation	0.004	0.996	0.000
H30.0 Focal chorioretinal inflammation	0.004	0.996	0.000
H31.9 Disorder of choroid, unspecified	0.004	0.996	0.000
H31.8 Other specified disorders of choroid	0.004	0.996	0.000
H31.4 Choroidal detachment	0.004	0.996	0.000
H31.3 Choroidal haemorrhage and rupture	0.004	0.996	0.000
H31.2 Hereditary choroidal dystrophy	0.004	0.996	0.000
H31.1 Choroidal degeneration	0.004	0.996	0.000
H31.0 Chorioretinal scars	0.004	0.996	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.996	0.004
H36.8 Other retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
N76.2 Acute vulvitis	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.996	0.004
H43.8 Other disorders of vitreous body	0.004	0.996	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.996	0.004
H36.0 Diabetic retinopathy	0.004	0.996	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
N76.0 Acute vaginitis	0.000	0.996	0.004
N13.6 Pyonephrosis	0.000	0.996	0.004
S32.00 Fracture of lumbar vertebra (closed)	0.004	0.996	0.000
C81 Hodgkin's disease	0.004	0.996	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.996	0.003
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.003
N76.6 Ulceration of vulva	0.000	0.996	0.003
N76.5 Ulceration of vagina	0.000	0.996	0.003
N76.3 Subacute and chronic vulvitis	0.000	0.996	0.003
N76.1 Subacute and chronic vaginitis	0.000	0.996	0.003
H34.9 Retinal vascular occlusion, unspecified	0.003	0.996	0.000
H34.2 Other retinal artery occlusions	0.003	0.996	0.000
H34.1 Central retinal artery occlusion	0.003	0.996	0.000
H34.0 Transient retinal artery occlusion	0.003	0.996	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.997	0.003
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.997	0.003
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
C81.1 Nodular sclerosis	0.003	0.997	0.000
M16.1 Other primary coxarthrosis	0.000	0.997	0.003
C84 Peripheral and cutaneous T-cell lymphomas	0.003	0.997	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.997	0.003
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.997	0.003
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.997	0.003
K43.4 Parastomal hernia with gangrene	0.000	0.997	0.003
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.997	0.003
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.997	0.003
K43.1 Ventral hernia with gangrene	0.000	0.997	0.003
Z40 Prophylactic surgery	0.003	0.997	0.000
C88 Malignant immunoproliferative diseases	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
H35 Other retinal disorders	0.003	0.997	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.003	0.997	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.997	0.003
N10 Acute tubulo-interstitial nephritis	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
C95 Leukaemia of unspecified cell type	0.003	0.997	0.000
C94 Other leukaemias of specified cell type	0.003	0.997	0.000
C93 Monocytic leukaemia	0.003	0.997	0.000
C86 Other specified types of T/NK-cell lymphoma	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
C81.7 Other Hodgkin's disease	0.003	0.997	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.003	0.997	0.000
C81.3 Lymphocytic depletion	0.003	0.997	0.000
C81.2 Mixed cellularity	0.003	0.997	0.000
C81.0 Lymphocytic predominance	0.003	0.997	0.000
C92 Myeloid leukaemia	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.003	0.997	0.000
H35.4 Peripheral retinal degeneration	0.003	0.997	0.000
S61 Open wound of wrist and hand	0.000	0.997	0.003
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.997	0.003
N15 Other renal tubulo-interstitial diseases	0.000	0.997	0.003
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.997	0.003
N11 Chronic tubulo-interstitial nephritis	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
C83.7 Burkitt's tumour	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.002	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.997	0.003
C84.9 Mature T/NK-cell lymphoma, unspecified	0.002	0.997	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.002	0.997	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.002	0.997	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.002	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.002	0.997	0.000
C84.3 Lymphoepithelioid lymphoma	0.002	0.997	0.000
C84.2 T-zone lymphoma	0.002	0.997	0.000
C84.1 Sezary's diease	0.002	0.997	0.000
C84.0 Mycosis fungoides	0.002	0.997	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
H35.5 Hereditary retinal dystrophy	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
Z40.9 Prophylactic surgery, unspecified	0.002	0.997	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.002	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.002	0.997	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.002	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.002	0.997	0.000
C88.2 Gamma heavy chain disease	0.002	0.997	0.000
C88.1 Alpha heavy chain disease	0.002	0.997	0.000
Z40.8 Other prophylactic surgery	0.002	0.997	0.000
N75 Diseases of Bartholin's gland	0.000	0.997	0.003
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.997	0.003
H35.1 Retinopathy of prematurity	0.002	0.997	0.000
N30.8 Other cystitis	0.000	0.997	0.003
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.002	0.997	0.000
C82.6 Cutaneous follicle centre lymphoma	0.002	0.997	0.000
C82.5 Diffuse follicle centre lymphoma	0.002	0.997	0.000
C82.4 Follicular lymphoma grade IIIb	0.002	0.997	0.000
C82.3 Follicular lymphoma grade IIIa	0.002	0.997	0.000
C82.2 Large cell, follicular	0.002	0.997	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.997	0.000
C82.0 Small cleaved cell, follicular	0.002	0.997	0.000
C91 Lymphoid leukaemia	0.002	0.997	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.002
H35.6 Retinal haemorrhage	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.998	0.002
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.002	0.998	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.002	0.998	0.000
C86.4 Blastic NK-cell lymphoma	0.002	0.998	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.002	0.998	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.002	0.998	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.002	0.998	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.002	0.998	0.000
C93.9 Monocytic leukaemia, unspecified	0.002	0.998	0.000
C93.7 Other monocytic leukaemia	0.002	0.998	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.002	0.998	0.000
C93.2 Subacute monocytic leukaemia	0.002	0.998	0.000
C93.1 Chronic monocytic leukaemia	0.002	0.998	0.000
C93.0 Acute monocytic leukaemia	0.002	0.998	0.000
C94.7 Other specified leukaemias	0.002	0.998	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.002	0.998	0.000
C94.5 Acute myelofibrosis	0.002	0.998	0.000
C94.4 Acute panmyelosis	0.002	0.998	0.000
C94.3 Mast cell leukaemia	0.002	0.998	0.000
C94.2 Acute megakaryoblastic leukaemia	0.002	0.998	0.000
C94.1 Chronic erythraemia	0.002	0.998	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.002	0.998	0.000
C95.9 Leukaemia, unspecified	0.002	0.998	0.000
C95.7 Other leukaemia of unspecified cell type	0.002	0.998	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.002	0.998	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.002	0.998	0.000
C95.0 Acute leukaemia of unspecified cell type	0.002	0.998	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
C96.8 Histiocytic sarcoma	0.002	0.998	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.002	0.998	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.002	0.998	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.002	0.998	0.000
C96.3 True histiocytic lymphoma	0.002	0.998	0.000
C96.2 Malignant mast cell tumour	0.002	0.998	0.000
C96.1 Malignant histiocytosis	0.002	0.998	0.000
C96.0 Letterer-Siwe disease	0.002	0.998	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.000	0.998	0.002
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.998	0.002
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.998	0.002
C92.9 Myeloid leukaemia, unspecified	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.002	0.998	0.000
C92.5 Acute myelomonocytic leukaemia	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
C92.3 Myeloid sarcoma	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.002	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
G40.9 Epilepsy, unspecified	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.998	0.002
N14.3 Nephropathy induced by heavy metals	0.000	0.998	0.002
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.998	0.002
N14.0 Analgesic nephropathy	0.000	0.998	0.002
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.998	0.002
N15.1 Renal and perinephric abscess	0.000	0.998	0.002
N15.0 Balkan nephropathy	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.998	0.002
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.998	0.002
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.998	0.002
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.998	0.002
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.998	0.002
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.998	0.002
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.002	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.998	0.002
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.998	0.002
N71 Inflammatory disease of uterus, except cervix	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.998	0.002
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.998	0.002
N75.8 Other diseases of Bartholin's gland	0.000	0.998	0.002
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.000	0.998	0.002
C91.9 Lymphoid leukaemia, unspecified	0.002	0.998	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.002	0.998	0.000
C91.7 Other lymphoid leukaemia	0.002	0.998	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.002	0.998	0.000
C91.5 Adult T-cell leukaemia	0.002	0.998	0.000
C91.4 Hairy-cell leukaemia	0.002	0.998	0.000
C91.3 Prolymphocytic leukaemia	0.002	0.998	0.000
C91.2 Subacute lymphocytic leukaemia	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
H43 Disorders of vitreous body	0.002	0.998	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
C34.0 Main bronchus	0.002	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.998	0.002
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.998	0.002
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.998	0.002
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.000	0.998	0.002
N71.0 Acute inflammatory disease of uterus	0.000	0.998	0.002
H35.8 Other specified retinal disorders	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
Z90.7 Acquired absence of genital organ(s)	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.000	0.998	0.002
N74.4 Female chlamydial pelvic inflammatory disease	0.000	0.998	0.002
N74.3 Female gonococcal pelvic inflammatory disease	0.000	0.998	0.002
N74.2 Female syphilitic pelvic inflammatory disease	0.000	0.998	0.002
N74.1 Female tuberculous pelvic inflammatory disease	0.000	0.998	0.002
N74.0 Tuberculous infection of cervix uteri	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.998	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S32.3 Fracture of ilium	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.001
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
N73 Other female pelvic inflammatory diseases	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
S32.5 Fracture of pubis	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.001	0.998	0.000
T39.0 Salicylates	0.001	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.001	0.998	0.000
N70.0 Acute salpingitis and oophoritis	0.000	0.998	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.001	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.001
S92.2 Fracture of other tarsal bone(s)	0.001	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.001
S32.10 Fracture of sacrum (closed)	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
S32.11 Fracture of sacrum (open)	0.001	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.001	0.998	0.000
H44.2 Degenerative myopia	0.001	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
N39.8 Other specified disorders of urinary system	0.000	0.998	0.002
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.001
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.001	0.998	0.000
S32.21 Fracture of coccyx (open)	0.001	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.001	0.998	0.000
S32.31 Fracture of ilium (open)	0.001	0.998	0.000
S32.30 Fracture of ilium (closed)	0.001	0.998	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.001	0.998	0.000
Z88.2 Personal history of allergy to sulphonamides	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.998	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.998	0.001
N73.5 Female pelvic peritonitis, unspecified	0.000	0.998	0.001
N73.4 Female chronic pelvic peritonitis	0.000	0.998	0.001
N73.3 Female acute pelvic peritonitis	0.000	0.998	0.001
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.998	0.001
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.998	0.001
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.998	0.001
H44 Disorders of globe	0.001	0.998	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
H44.0 Purulent endophthalmitis	0.001	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
S90.0 Contusion of ankle	0.001	0.998	0.000
S27.0 Traumatic pneumothorax	0.001	0.999	0.000
S31.0 Open wound of lower back and pelvis	0.001	0.999	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.999	0.001
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.999	0.001
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.999	0.001
J33 Nasal polyp	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.001	0.999	0.000
C34.2 Middle lobe, bronchus or lung	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
C34.3 Lower lobe, bronchus or lung	0.001	0.999	0.000
T63.4 Venom of other arthropods	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
C34.8 Overlapping lesion of bronchus and lung	0.001	0.999	0.000
C90.0 Multiple myeloma	0.001	0.999	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.001	0.999	0.000
N28.1 Cyst of kidney, acquired	0.000	0.999	0.001
S92.7 Multiple fractures of foot	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.999	0.001
S31 Open wound of abdomen, lower back and pelvis	0.001	0.999	0.000
S81 Open wound of lower leg	0.001	0.999	0.000
S32.41 Fracture of acetabulum (open)	0.001	0.999	0.000
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations