TreeWAS – Variant ID: rs74827573

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
# Top node	1.000	0.000
K20 Oesophagitis	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.997	0.003
K29 Gastritis and duodenitis	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.994	0.006
D60-D64 Aplastic and other anaemias	0.993	0.007
D64 Other anaemias	0.989	0.011
T36-T50 Poisoning by drugs, medicaments and biological substances	0.987	0.013
D64.9 Anaemia, unspecified	0.987	0.013
K90-K93 Other diseases of the digestive system	0.985	0.015
K29.8 Duodenitis	0.985	0.015
Chapter V Mental and behavioural disorders	0.983	0.017
Chapter XXI Factors influencing health status and contact with health services	0.983	0.017
K55-K64 Other diseases of intestines	0.971	0.029
M45-M49 Spondylopathies	0.969	0.031
F40-F48 Neurotic, stress-related and somatoform disorders	0.968	0.032
K26 Duodenal ulcer	0.961	0.039
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.959	0.041
K40-K46 Hernia	0.958	0.042
K92 Other diseases of digestive system	0.954	0.046
F41 Other anxiety disorders	0.950	0.050
Z00-Z13 Persons encountering health services for examination and investigation	0.948	0.052
Chapter I Certain infectious and parasitic diseases	0.944	0.056
K62 Other diseases of anus and rectum	0.941	0.059
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.940	0.060
M47 Spondylosis	0.935	0.065
K29.7 Gastritis, unspecified	0.935	0.065
S80-S89 Injuries to the knee and lower leg	0.932	0.068
Chapter XX External causes of morbidity and mortality	0.930	0.070
Chapter XV Pregnancy, childbirth and the puerperium	0.924	0.076
Chapter II Neoplasms	0.922	0.078
K62.1 Rectal polyp	0.922	0.078
F41.2 Mixed anxiety and depressive disorder	0.920	0.080
K59 Other functional intestinal disorders	0.909	0.091
Z12 Special screening examination for neoplasms	0.909	0.091
K92.1 Melaena	0.907	0.093
M47.9 Spondylosis, unspecified	0.905	0.095
Z95 Presence of cardiac and vascular implants and grafts	0.904	0.096
K40 Inguinal hernia	0.901	0.099
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.900	0.100
T84.1 Mechanical complication of internal fixation device of bones of limb	0.895	0.105
Z95.1 Presence of aortocoronary bypass graft	0.890	0.110
S40-S49 Injuries to the shoulder and upper arm	0.887	0.113
C15-C26 Malignant neoplasms of digestive organs	0.887	0.113
K29.6 Other gastritis	0.886	0.114
Z90 Acquired absence of organs, not elsewhere classified	0.885	0.115
M50-M54 Other dorsopathies	0.881	0.119
Z12.1 Special screening examination for neoplasm of intestinal tract	0.881	0.119
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.881	0.119
D50-D53 Nutritional anaemias	0.871	0.129
S82 Fracture of lower leg, including ankle	0.870	0.130
K70-K77 Diseases of liver	0.866	0.134
F41.9 Anxiety disorder, unspecified	0.864	0.136
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.863	0.137
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.859	0.141
M46 Other inflammatory spondylopathies	0.855	0.145
Z93 Artificial opening status	0.852	0.148
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.850	0.150
K56 Paralytic ileus and intestinal obstruction without hernia	0.848	0.152
B35-B49 Mycoses	0.847	0.153
K26.3 Acute without haemorrhage or perforation	0.847	0.153
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.844	0.156
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.844	0.156
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.841	0.159
M20-M25 Other joint disorders	0.841	0.159
Chapter VIII Diseases of the ear and mastoid process	0.841	0.159
Z87 Personal history of other diseases and conditions	0.841	0.159
K59.0 Constipation	0.836	0.164
K92.2 Gastro-intestinal haemorrhage, unspecified	0.835	0.165
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.835	0.165
Z11 Special screening examination for infectious and parasitic diseases	0.829	0.171
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.828	0.172
M40-M43 Deforming dorsopathies	0.825	0.175
B95-B98 Bacterial, viral and other infectious agents	0.825	0.175
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.821	0.179
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.820	0.180
Z87.1 Personal history of diseases of the digestive system	0.820	0.180
C19 Malignant neoplasm of rectosigmoid junction	0.819	0.181
O60-O75 Complications of labour and delivery	0.818	0.182
S10-S19 Injuries to the neck	0.815	0.185
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.814	0.185
T84.2 Mechanical complication of internal fixation device of other bones	0.811	0.189
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.811	0.189
Z02 Examination and encounter for administrative purposes	0.809	0.191
K62.6 Ulcer of anus and rectum	0.807	0.193
S42 Fracture of shoulder and upper arm	0.806	0.194
K26.4 Chronic or unspecified with haemorrhage	0.804	0.196
T46 Poisoning by agents primarily affecting the cardiovascular system	0.802	0.198
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.801	0.198
K92.9 Disease of digestive system, unspecified	0.800	0.200
D00-D09 In situ neoplasms	0.800	0.200
M80-M85 Disorders of bone density and structure	0.798	0.202
T88 Other complications of surgical and medical care, not elsewhere classified	0.798	0.202
D50 Iron deficiency anaemia	0.797	0.203
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.796	0.204
F60-F69 Disorders of adult personality and behaviour	0.796	0.204
S70-S79 Injuries to the hip and thigh	0.795	0.205
Z04 Examination and observation for other reasons	0.791	0.209
K43 Ventral hernia	0.790	0.210
K31 Other diseases of stomach and duodenum	0.789	0.211
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.787	0.213
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.783	0.217
T66-T78 Other and unspecified effects of external causes	0.783	0.217
K26.5 Chronic or unspecified with perforation	0.781	0.219
C20 Malignant neoplasm of rectum	0.777	0.223
M35 Other systemic involvement of connective tissue	0.775	0.225
M47.96 Spondylosis, unspecified (Lumbar region)	0.775	0.225
Z90.4 Acquired absence of other parts of digestive tract	0.774	0.226
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.773	0.227
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.772	0.227
M05-M14 Inflammatory polyarthropathies	0.772	0.228
S50-S59 Injuries to the elbow and forearm	0.772	0.228
M15-M19 Arthrosis	0.771	0.229
D50.8 Other iron deficiency anaemias	0.770	0.230
K90 Intestinal malabsorption	0.768	0.232
K07 Dentofacial anomalies [including malocclusion]	0.766	0.234
C64-C68 Malignant neoplasms of urinary tract	0.765	0.235
A30-A49 Other bacterial diseases	0.765	0.235
K59.3 Megacolon, not elsewhere classified	0.765	0.235
T85 Complications of other internal prosthetic devices, implants and grafts	0.764	0.236
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.764	0.236
F43 Reaction to severe stress, and adjustment disorders	0.762	0.238
K04 Diseases of pulp and periapical tissues	0.762	0.238
B37 Candidiasis	0.762	0.238
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.761	0.239
M54 Dorsalgia	0.761	0.239
K29.0 Acute haemorrhagic gastritis	0.760	0.240
S20-S29 Injuries to the thorax	0.759	0.240
Z83 Family history of other specific disorders	0.759	0.241
D63 Anaemia in chronic diseases classified elsewhere	0.758	0.242
K42 Umbilical hernia	0.758	0.242
M47.92 Spondylosis, unspecified (Cervical region)	0.758	0.242
M47.99 Spondylosis, unspecified (Site unspecified)	0.756	0.244
K75 Other inflammatory liver diseases	0.756	0.244
O70 Perineal laceration during delivery	0.755	0.245
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.754	0.246
M86-M90 Other osteopathies	0.751	0.249
D37-D48 Neoplasms of uncertain or unknown behaviour	0.751	0.249
C51-C58 Malignant neoplasms of female genital organs	0.751	0.249
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.750	0.250
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.750	0.250
H65-H75 Diseases of middle ear and mastoid	0.750	0.250
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.750	0.250
Chapter XXII Codes for special purposes	0.749	0.251
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.749	0.251
F00-F09 Organic, including symptomatic, mental disorders	0.749	0.251
Z98 Other postsurgical states	0.748	0.252
S42.2 Fracture of upper end of humerus	0.747	0.253
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.746	0.254
S90-S99 Injuries to the ankle and foot	0.744	0.256
Z11.0 Special screening examination for intestinal infectious diseases	0.744	0.256
T51 Toxic effect of alcohol	0.743	0.257
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.742	0.258
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.741	0.259
Z93.3 Colostomy status	0.741	0.259
S82.3 Fracture of lower end of tibia	0.741	0.259
F41.1 Generalised anxiety disorder	0.740	0.260
S82.6 Fracture of lateral malleolus	0.739	0.261
K27 Peptic ulcer, site unspecified	0.738	0.261
Z34 Supervision of normal pregnancy	0.738	0.262
K08 Other disorders of teeth and supporting structures	0.738	0.262
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.738	0.262
K63 Other diseases of intestine	0.738	0.262
F80-F89 Disorders of psychological development	0.737	0.263
M35.3 Polymyalgia rheumatica	0.736	0.264
F40 Phobic anxiety disorders	0.735	0.265
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.734	0.266
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.733	0.266
V10-V19 Pedal cyclist injured in transport accident	0.732	0.268
Z90.2 Acquired absence of lung [part of]	0.732	0.268
O34 Maternal care for known or suspected abnormality of pelvic organs	0.731	0.269
K62.8 Other specified diseases of anus and rectum	0.730	0.270
M25 Other joint disorders, not elsewhere classified	0.730	0.270
M50 Cervical disk disorders	0.730	0.270
Z90.6 Acquired absence of other parts of urinary tract	0.730	0.270
M47.8 Other spondylosis	0.729	0.271
D61 Other aplastic anaemias	0.728	0.272
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.727	0.273
K29.5 Chronic gastritis, unspecified	0.727	0.273
T15-T19 Effects of foreign body entering through natural orifice	0.726	0.274
M46.9 Inflammatory spondylopathy, unspecified	0.725	0.275
K22 Other diseases of oesophagus	0.724	0.276
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.723	0.277
W50-W64 Exposure to animate mechanical forces	0.721	0.279
K09 Cysts of oral region, not elsewhere classified	0.720	0.280
K28 Gastrojejunal ulcer	0.717	0.283
K23 Disorders of oesophagus in diseases classified elsewhere	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O94-O99 Other obstetric conditions, not elsewhere classified	0.716	0.284
Z94 Transplanted organ and tissue status	0.716	0.284
S81 Open wound of lower leg	0.715	0.284
T87 Complications peculiar to reattachment and amputation	0.715	0.285
T86 Failure and rejection of transplanted organs and tissues	0.715	0.285
T80 Complications following infusion, transfusion and therapeutic injection	0.715	0.285
K29.9 Gastroduodenitis, unspecified	0.715	0.285
K29.2 Alcoholic gastritis	0.715	0.285
M91-M94 Chondropathies	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
M00-M03 Infectious arthropathies	0.715	0.285
K91.4 Colostomy and enterostomy malfunction	0.715	0.285
D55-D59 Haemolytic anaemias	0.714	0.285
K56.5 Intestinal adhesions [bands] with obstruction	0.713	0.287
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.713	0.287
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.713	0.287
T84.3 Mechanical complication of other bone devices, implants and grafts	0.713	0.287
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.712	0.288
D62 Acute posthaemorrhagic anaemia	0.712	0.288
Z89 Acquired absence of limb	0.712	0.288
S82.2 Fracture of shaft of tibia	0.711	0.289
Z90.5 Acquired absence of kidney	0.711	0.289
Z90.8 Acquired absence of other organs	0.711	0.289
M53 Other dorsopathies, not elsewhere classified	0.710	0.290
Z02.8 Other examinations for administrative purposes	0.710	0.290
D64.8 Other specified anaemias	0.709	0.291
D64.4 Congenital dyserythropoietic anaemia	0.709	0.291
D64.3 Other sideroblastic anaemias	0.709	0.291
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.709	0.291
D64.1 Secondary sideroblastic anaemia due to disease	0.709	0.291
D64.0 Hereditary sideroblastic anaemia	0.709	0.291
Chapter VI Diseases of the nervous system	0.709	0.291
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.708	0.292
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.708	0.292
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.708	0.292
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.708	0.292
T41 Poisoning by anaesthetics and therapeutic gases	0.708	0.292
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.708	0.292
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.708	0.292
T36 Poisoning by systemic antibiotics	0.708	0.292
K41 Femoral hernia	0.707	0.293
K93 Disorders of other digestive organs in diseases classified elsewhere	0.706	0.294
K74 Fibrosis and cirrhosis of liver	0.705	0.295
F99-F99 Unspecified mental disorder	0.705	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.705	0.295
F70-F79 Mental retardation	0.705	0.295
M46.1 Sacro-iliitis, not elsewhere classified	0.704	0.296
S42.20 Fracture of upper end of humerus (closed)	0.704	0.296
Z04.8 Examination and observation for other specified reasons	0.704	0.296
K35-K38 Diseases of appendix	0.702	0.298
B37.8 Candidiasis of other sites	0.701	0.299
T50.9 Other and unspecified drugs, medicaments and biological substances	0.701	0.299
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.701	0.299
O47 False labour	0.699	0.301
Chapter XII Diseases of the skin and subcutaneous tissue	0.699	0.301
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.698	0.302
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.697	0.303
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.697	0.303
C21 Malignant neoplasm of anus and anal canal	0.696	0.303
K64 Haemorrhoids and perianal venous thrombosis	0.696	0.304
M49 Spondylopathies in diseases classified elsewhere	0.694	0.305
F48 Other neurotic disorders	0.694	0.306
F44 Dissociative [conversion] disorders	0.694	0.306
F42 Obsessive-compulsive disorder	0.694	0.306
D80-D89 Certain disorders involving the immune mechanism	0.693	0.307
F45 Somatoform disorders	0.690	0.310
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.690	0.310
K29.3 Chronic superficial gastritis	0.690	0.310
Z37 Outcome of delivery	0.689	0.311
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.689	0.311
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.689	0.311
K26.7 Chronic without haemorrhage or perforation	0.689	0.311
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.689	0.311
K26.2 Acute with both haemorrhage and perforation	0.689	0.311
K26.1 Acute with perforation	0.689	0.311
K26.0 Acute with haemorrhage	0.689	0.311
Y60-Y69 Misadventures to patients during surgical and medical care	0.688	0.312
S82.5 Fracture of medial malleolus	0.687	0.313
K45 Other abdominal hernia	0.687	0.313
S82.0 Fracture of patella	0.686	0.314
K08.8 Other specified disorders of teeth and supporting structures	0.686	0.314
D04 Carcinoma in situ of skin	0.686	0.314
V20-V29 Motorcycle rider injured in transport accident	0.685	0.315
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.684	0.316
K92.8 Other specified diseases of digestive system	0.684	0.316
K07.6 Temporomandibular joint disorders	0.684	0.316
X60-X84 Intentional self-harm	0.682	0.318
F41.8 Other specified anxiety disorders	0.681	0.318
F41.3 Other mixed anxiety disorders	0.681	0.318
Z29 Need for other prophylactic measures	0.681	0.319
C18 Malignant neoplasm of colon	0.680	0.320
Z10 Routine general health check-up of defined subpopulation	0.679	0.321
Z80 Family history of malignant neoplasm	0.679	0.321
O36 Maternal care for other known or suspected foetal problems	0.679	0.321
K62.0 Anal polyp	0.679	0.321
K65-K67 Diseases of peritoneum	0.678	0.322
K46 Unspecified abdominal hernia	0.678	0.322
M13 Other arthritis	0.677	0.323
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.677	0.323
B99-B99 Other infectious diseases	0.677	0.323
B90-B94 Sequelae of infectious and parasitic diseases	0.677	0.323
B85-B89 Pediculosis, acariasis and other infestations	0.677	0.323
B65-B83 Helminthiases	0.677	0.323
B50-B64 Protozoal diseases	0.677	0.323
B20-B24 Human immunodeficiency virus [HIV] disease	0.677	0.323
B15-B19 Viral hepatitis	0.677	0.323
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.677	0.323
A80-A89 Viral infections of the central nervous system	0.677	0.323
A75-A79 Rickettsioses	0.677	0.323
A70-A74 Other diseases caused by chlamydiae	0.677	0.323
A65-A69 Other spirochaetal diseases	0.677	0.323
A50-A64 Infections with a predominantly sexual mode of transmission	0.677	0.323
A20-A28 Certain zoonotic bacterial diseases	0.677	0.323
A15-A19 Tuberculosis	0.677	0.323
Z08 Follow-up examination after treatment for malignant neoplasm	0.676	0.324
M43 Other deforming dorsopathies	0.676	0.324
K62.2 Anal prolapse	0.675	0.325
H71 Cholesteatoma of middle ear	0.674	0.326
Z84 Family history of other conditions	0.674	0.326
Z81 Family history of mental and behavioural disorders	0.674	0.326
K62.9 Disease of anus and rectum, unspecified	0.674	0.326
H90-H95 Other disorders of ear	0.673	0.327
M65-M68 Disorders of synovium and tendon	0.672	0.328
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.672	0.328
W00-W19 Falls	0.671	0.329
M47.2 Other spondylosis with radiculopathy	0.671	0.329
M47.1 Other spondylosis with myelopathy	0.671	0.329
M47.0 Anterior spinal and vertebral artery compression syndromes	0.671	0.329
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.670	0.330
K06 Other disorders of gingiva and edentulous alveolar ridge	0.670	0.330
D52 Folate deficiency anaemia	0.670	0.330
T46.4 Angiotensin-converting-enzyme inhibitors	0.670	0.330
C56 Malignant neoplasm of ovary	0.668	0.332
S89 Other and unspecified injuries of lower leg	0.668	0.332
S88 Traumatic amputation of lower leg	0.668	0.332
S87 Crushing injury of lower leg	0.668	0.332
S86 Injury of muscle and tendon at lower leg level	0.668	0.332
S85 Injury of blood vessels at lower leg level	0.668	0.332
S84 Injury of nerves at lower leg level	0.668	0.332
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.667	0.333
Y10-Y34 Event of undetermined intent	0.667	0.333
Y00-Y09 Assault	0.667	0.333
X85-X99 Assault	0.667	0.333
X58-X59 Accidental exposure to other and unspecified factors	0.667	0.333
X50-X57 Overexertion, travel and privation	0.667	0.333
X40-X49 Accidental poisoning by and exposure to noxious substances	0.667	0.333
X30-X39 Exposure to forces of nature	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.667	0.333
X10-X19 Contact with heat and hot substances	0.667	0.333
X00-X09 Exposure to smoke, fire and flames	0.667	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.667	0.333
W75-W84 Other accidental threats to breathing	0.667	0.333
W65-W74 Accidental drowning and submersion	0.667	0.333
V98-V99 Other and unspecified transport accidents	0.667	0.333
V95-V97 Air and space transport accidents	0.667	0.333
V90-V94 Water transport accidents	0.667	0.333
V80-V89 Other land transport accidents	0.667	0.333
V70-V79 Bus occupant injured in transport accident	0.667	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.667	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.667	0.333
V40-V49 Car occupant injured in transport accident	0.667	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.667	0.333
V01-V09 Pedestrian injured in transport accident	0.667	0.333
T51.0 Ethanol	0.666	0.334
Z95.8 Presence of other cardiac and vascular implants and grafts	0.663	0.337
O85-O92 Complications predominantly related to the puerperium	0.663	0.337
O20-O29 Other maternal disorders predominantly related to pregnancy	0.663	0.337
F60 Specific personality disorders	0.662	0.338
Chapter IX Diseases of the circulatory system	0.662	0.338
Z87.0 Personal history of diseases of the respiratory system	0.662	0.338
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.661	0.339
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.661	0.339
C40-C41 Malignant neoplasms of bone and articular cartilage	0.661	0.339
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.660	0.339
K61 Abscess of anal and rectal regions	0.660	0.339
O40 Polyhydramnios	0.660	0.340
Z93.1 Gastrostomy status	0.660	0.340
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.659	0.341
A00-A09 Intestinal infectious diseases	0.658	0.342
W20-W49 Exposure to inanimate mechanical forces	0.658	0.342
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.657	0.343
Z39 Postpartum care and examination	0.657	0.343
Z90.3 Acquired absence of part of stomach	0.656	0.344
K56.2 Volvulus	0.656	0.344
K04.8 Radicular cyst	0.655	0.345
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.655	0.345
M25.7 Osteophyte	0.655	0.345
O70.2 Third degree perineal laceration during delivery	0.655	0.345
T39.0 Salicylates	0.654	0.346
Z93.6 Other artificial openings of urinary tract status	0.654	0.346
K56.6 Other and unspecified intestinal obstruction	0.654	0.346
B35 Dermatophytosis	0.653	0.347
O34.2 Maternal care due to uterine scar from previous surgery	0.653	0.347
K59.9 Functional intestinal disorder, unspecified	0.652	0.348
K59.4 Anal spasm	0.652	0.348
K59.2 Neurogenic bowel, not elsewhere classified	0.652	0.348
K59.1 Functional diarrhoea	0.652	0.348
M22 Disorders of patella	0.652	0.348
Z12.9 Special screening examination for neoplasm, unspecified	0.651	0.348
Z12.8 Special screening examination for neoplasm of other sites	0.651	0.348
Z12.6 Special screening examination for neoplasm of bladder	0.651	0.348
Z12.5 Special screening examination for neoplasm of prostate	0.651	0.348
Z12.4 Special screening examination for neoplasm of cervix	0.651	0.348
Z12.3 Special screening examination for neoplasm of breast	0.651	0.348
Z12.2 Special screening examination for neoplasm of respiratory organs	0.651	0.348
Z12.0 Special screening examination for neoplasm of stomach	0.651	0.348
Y83.6 Removal of other organ (partial) (total)	0.652	0.348
S82.30 Fracture of lower end of tibia (closed)	0.649	0.351
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.649	0.351
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.649	0.351
M47.94 Spondylosis, unspecified (Thoracic region)	0.649	0.351
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.649	0.351
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.649	0.351
Z95.4 Presence of other heart-valve replacement	0.649	0.351
Z95.3 Presence of xenogenic heart valve	0.648	0.352
T43.0 Tricyclic and tetracyclic antidepressants	0.648	0.352
K76 Other diseases of liver	0.647	0.353
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.647	0.353
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.646	0.354
K40.1 Bilateral inguinal hernia, with gangrene	0.646	0.354
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.646	0.354
S82.60 Fracture of lateral malleolus (closed)	0.646	0.354
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.645	0.354
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.645	0.354
A40 Streptococcal septicaemia	0.645	0.355
Z95.2 Presence of prosthetic heart valve	0.644	0.356
Chapter X Diseases of the respiratory system	0.644	0.356
M45 Ankylosing spondylitis	0.643	0.357
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.642	0.358
K44 Diaphragmatic hernia	0.642	0.358
H72 Perforation of tympanic membrane	0.642	0.358
C15 Malignant neoplasm of oesophagus	0.642	0.358
K31.9 Disease of stomach and duodenum, unspecified	0.642	0.358
K55 Vascular disorders of intestine	0.641	0.358
D70-D77 Other diseases of blood and blood-forming organs	0.641	0.359
M54.4 Lumbago with sciatica	0.640	0.360
T43.5 Other and unspecified antipsychotics and neuroleptics	0.640	0.360
Z97 Presence of other devices	0.638	0.362
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.638	0.362
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.637	0.363
K22.4 Dyskinesia of oesophagus	0.637	0.363
K75.4 Autoimmune hepatitis	0.637	0.363
T43.3 Phenothiazine antipsychotics and neuroleptics	0.637	0.363
M34 Systemic sclerosis	0.637	0.363
S49 Other and unspecified injuries of shoulder and upper arm	0.636	0.364
S48 Traumatic amputation of shoulder and upper arm	0.636	0.364
S46 Injury of muscle and tendon at shoulder and upper arm level	0.636	0.364
S45 Injury of blood vessels at shoulder and upper arm level	0.636	0.364
S44 Injury of nerves at shoulder and upper arm level	0.636	0.364
S41 Open wound of shoulder and upper arm	0.636	0.364
S40 Superficial injury of shoulder and upper arm	0.636	0.364
S47 Crushing injury of shoulder and upper arm	0.636	0.364
C26 Malignant neoplasm of other and ill-defined digestive organs	0.636	0.364
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.636	0.364
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.636	0.364
C17 Malignant neoplasm of small intestine	0.636	0.364
C23 Malignant neoplasm of gallbladder	0.636	0.364
M54.5 Low back pain	0.636	0.364
D03 Melanoma in situ	0.635	0.364
Z90.0 Acquired absence of part of head and neck	0.635	0.365
O41 Other disorders of amniotic fluid and membranes	0.634	0.365
S19 Other and unspecified injuries of neck	0.634	0.366
S79 Other and unspecified injuries of hip and thigh	0.634	0.366
M16 Coxarthrosis [arthrosis of hip]	0.634	0.366
M41 Scoliosis	0.633	0.367
K62.4 Stenosis of anus and rectum	0.633	0.367
O70.0 First degree perineal laceration during delivery	0.633	0.367
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.633	0.367
K59.8 Other specified functional intestinal disorders	0.632	0.368
O80-O84 Delivery	0.632	0.368
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.631	0.368
K10 Other diseases of jaws	0.631	0.369
K03 Other diseases of hard tissues of teeth	0.631	0.369
K00 Disorders of tooth development and eruption	0.631	0.369
K43.0 Ventral hernia with obstruction, without gangrene	0.631	0.369
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.631	0.369
K62.3 Rectal prolapse	0.629	0.371
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.629	0.371
G90-G99 Other disorders of the nervous system	0.629	0.371
G80-G83 Cerebral palsy and other paralytic syndromes	0.629	0.371
M80 Osteoporosis with pathological fracture	0.628	0.371
Z93.0 Tracheostomy status	0.628	0.372
T78 Adverse effects, not elsewhere classified	0.628	0.372
M70-M79 Other soft tissue disorders	0.627	0.372
M18 Arthrosis of first carpometacarpal joint	0.627	0.373
M48 Other spondylopathies	0.626	0.374
Y83.4 Other reconstructive surgery	0.626	0.374
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.626	0.374
Z93.5 Cystostomy status	0.626	0.374
D53 Other nutritional anaemias	0.624	0.375
M24 Other specific joint derangements	0.624	0.376
S51 Open wound of forearm	0.624	0.376
S82.9 Fracture of lower leg, part unspecified	0.623	0.376
S82.7 Multiple fractures of lower leg	0.623	0.376
M84 Disorders of continuity of bone	0.623	0.377
S20 Superficial injury of thorax	0.623	0.377
K62.7 Radiation proctitis	0.623	0.377
C25 Malignant neoplasm of pancreas	0.623	0.377
K04.7 Periapical abscess without sinus	0.621	0.378
Z98.8 Other specified postsurgical states	0.621	0.378

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations