TreeWAS – Variant ID: rs74967533

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter VIII Diseases of the ear and mastoid process	0.997	0.003
Z40-Z54 Persons encountering health services for specific procedures and health care	0.996	0.004
Chapter V Mental and behavioural disorders	0.996	0.004
Z53 Persons encountering health services for specifie procedures, not carried out	0.996	0.004
Chapter II Neoplasms	0.995	0.005
Z53.8 Procedure not carried out for other reasons	0.993	0.007
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.989	0.011
Chapter IX Diseases of the circulatory system	0.985	0.015
M20-M25 Other joint disorders	0.984	0.016
F30-F39 Mood [affective] disorders	0.977	0.023
H65-H75 Diseases of middle ear and mastoid	0.973	0.027
Z53.0 Procedure not carried out because of contraindication	0.972	0.028
Chapter XIV Diseases of the genitourinary system	0.970	0.030
H90-H95 Other disorders of ear	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.963	0.037
M25 Other joint disorders, not elsewhere classified	0.963	0.037
Z90 Acquired absence of organs, not elsewhere classified	0.962	0.038
F32 Depressive episode	0.956	0.044
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.948	0.052
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.948	0.052
M50-M54 Other dorsopathies	0.946	0.054
F40-F48 Neurotic, stress-related and somatoform disorders	0.945	0.055
E00-E07 Disorders of thyroid gland	0.935	0.065
I10-I15 Hypertensive diseases	0.933	0.067
D10-D36 Benign neoplasms	0.931	0.069
F32.9 Depressive episode, unspecified	0.930	0.070
C79 Secondary malignant neoplasm of other sites	0.930	0.070
Chapter XX External causes of morbidity and mortality	0.928	0.072
S60-S69 Injuries to the wrist and hand	0.928	0.072
Z93 Artificial opening status	0.928	0.072
Z90.4 Acquired absence of other parts of digestive tract	0.925	0.075
I70-I79 Diseases of arteries, arterioles and capillaries	0.923	0.077
H91 Other hearing loss	0.922	0.078
C51-C58 Malignant neoplasms of female genital organs	0.922	0.078
N60-N64 Disorders of breast	0.920	0.080
Z86 Personal history of certain other diseases	0.919	0.081
T36-T50 Poisoning by drugs, medicaments and biological substances	0.918	0.082
S80-S89 Injuries to the knee and lower leg	0.917	0.083
D25 Leiomyoma of uterus	0.917	0.083
M25.5 Pain in joint	0.916	0.084
E03 Other hypothyroidism	0.914	0.086
M20 Acquired deformities of fingers and toes	0.914	0.086
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.910	0.090
S00-S09 Injuries to the head	0.905	0.095
F41 Other anxiety disorders	0.903	0.097
E03.9 Hypothyroidism, unspecified	0.899	0.101
Z90.7 Acquired absence of genital organ(s)	0.894	0.106
C43-C44 Melanoma and other malignant neoplasms of skin	0.892	0.108
H91.9 Hearing loss, unspecified	0.891	0.109
I12 Hypertensive renal disease	0.888	0.112
I30-I52 Other forms of heart disease	0.886	0.114
H72 Perforation of tympanic membrane	0.886	0.114
M05-M14 Inflammatory polyarthropathies	0.884	0.116
Z92 Personal history of medical treatment	0.882	0.118
M25.7 Osteophyte	0.878	0.122
N10-N16 Renal tubulo-interstitial diseases	0.877	0.123
Z45 Adjustment and management of implanted device	0.872	0.128
Z86.4 Personal history of psychoactive substance abuse	0.871	0.129
Z95 Presence of cardiac and vascular implants and grafts	0.871	0.129
D50-D53 Nutritional anaemias	0.870	0.130
D25.9 Leiomyoma of uterus, unspecified	0.866	0.134
Z93.3 Colostomy status	0.866	0.134
N60 Benign mammary dysplasia	0.862	0.138
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.862	0.138
Z98 Other postsurgical states	0.861	0.139
D25.2 Subserosal leiomyoma of uterus	0.860	0.140
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.856	0.144
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.856	0.144
I12.0 Hypertensive renal disease with renal failure	0.851	0.149
C44 Other malignant neoplasms of skin	0.851	0.149
M25.55 Pain in joint (Pelvic region and thigh)	0.848	0.152
Chapter I Certain infectious and parasitic diseases	0.848	0.152
C54 Malignant neoplasm of corpus uteri	0.847	0.153
M45-M49 Spondylopathies	0.846	0.154
S70-S79 Injuries to the hip and thigh	0.845	0.155
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.844	0.156
D37-D48 Neoplasms of uncertain or unknown behaviour	0.840	0.160
Z70-Z76 Persons encountering health services in other circumstances	0.836	0.164
V10-V19 Pedal cyclist injured in transport accident	0.836	0.164
M51 Other intervertebral disk disorders	0.834	0.166
D50 Iron deficiency anaemia	0.834	0.166
H90 Conductive and sensorineural hearing loss	0.830	0.170
N63 Unspecified lump in breast	0.828	0.172
F41.2 Mixed anxiety and depressive disorder	0.827	0.173
H72.9 Perforation of tympanic membrane, unspecified	0.824	0.176
M20.4 Other hammer toe(s) (acquired)	0.824	0.176
N13 Obstructive and reflux uropathy	0.818	0.182
I77 Other disorders of arteries and arterioles	0.817	0.183
N30-N39 Other diseases of urinary system	0.817	0.183
H71 Cholesteatoma of middle ear	0.816	0.184
Z45.0 Adjustment and management of cardiac pacemaker	0.815	0.185
S40-S49 Injuries to the shoulder and upper arm	0.814	0.186
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.813	0.187
I71 Aortic aneurysm and dissection	0.808	0.192
Z92.6 Personal history of chemotherapy for neoplastic disease	0.808	0.192
E20-E35 Disorders of other endocrine glands	0.807	0.193
S01 Open wound of head	0.806	0.194
M22 Disorders of patella	0.806	0.194
Z95.4 Presence of other heart-valve replacement	0.805	0.195
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.801	0.199
Z52 Donors of organs and tissues	0.799	0.201
S82 Fracture of lower leg, including ankle	0.798	0.202
S50-S59 Injuries to the elbow and forearm	0.798	0.202
T66-T78 Other and unspecified effects of external causes	0.797	0.203
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.796	0.204
D50.9 Iron deficiency anaemia, unspecified	0.794	0.206
F31 Bipolar affective disorder	0.794	0.206
C54.1 Endometrium	0.794	0.206
F00-F09 Organic, including symptomatic, mental disorders	0.793	0.207
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.792	0.208
H74 Other disorders of middle ear and mastoid	0.792	0.208
T84.0 Mechanical complication of internal joint prosthesis	0.792	0.208
M25.57 Pain in joint (Ankle and foot)	0.791	0.209
M54 Dorsalgia	0.791	0.209
Z90.6 Acquired absence of other parts of urinary tract	0.788	0.212
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.787	0.213
I26 Pulmonary embolism	0.786	0.214
Z92.3 Personal history of irradiation	0.783	0.217
E65-E68 Obesity and other hyperalimentation	0.783	0.217
S06 Intracranial injury	0.783	0.217
D35 Benign neoplasm of other and unspecified endocrine glands	0.780	0.220
S62 Fracture at wrist and hand level	0.779	0.221
R07 Pain in throat and chest	0.779	0.221
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.778	0.222
F32.3 Severe depressive episode with psychotic symptoms	0.775	0.225
H66 Suppurative and unspecified otitis media	0.775	0.225
M20.5 Other deformities of toe(s) (acquired)	0.775	0.225
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.775	0.225
Chapter VI Diseases of the nervous system	0.774	0.226
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.773	0.226
S90-S99 Injuries to the ankle and foot	0.772	0.228
M25.75 Osteophyte (Pelvic region and thigh)	0.771	0.229
V18 Pedal cyclist injured in noncollision transport accident	0.770	0.230
R07.3 Other chest pain	0.770	0.230
I49 Other cardiac arrhythmias	0.769	0.231
M20.6 Acquired deformity of toe(s), unspecified	0.767	0.233
M50 Cervical disk disorders	0.767	0.233
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.765	0.234
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.764	0.236
T88 Other complications of surgical and medical care, not elsewhere classified	0.763	0.237
Z98.1 Arthrodesis status	0.762	0.238
Chapter XI Diseases of the digestive system	0.761	0.239
Z43 Attention to artificial openings	0.761	0.239
M51.2 Other specified intervertebral disk displacement	0.761	0.239
C44.4 Skin of scalp and neck	0.761	0.239
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.761	0.239
Z48 Other surgical follow-up care	0.760	0.240
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.760	0.240
H73 Other disorders of tympanic membrane	0.759	0.240
T81 Complications of procedures, not elsewhere classified	0.758	0.242
F41.9 Anxiety disorder, unspecified	0.757	0.243
N80-N98 Noninflammatory disorders of female genital tract	0.757	0.243
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.756	0.244
N60.1 Diffuse cystic mastopathy	0.755	0.245
N00-N08 Glomerular diseases	0.755	0.245
M65-M68 Disorders of synovium and tendon	0.754	0.245
S10-S19 Injuries to the neck	0.754	0.246
C79.8 Secondary malignant neoplasm of other specified sites	0.754	0.246
Z92.1 Personal history of long-term (current) use of anticoagulants	0.754	0.246
M06 Other rheumatoid arthritis	0.754	0.246
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.753	0.247
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.752	0.248
M25.77 Osteophyte (Ankle and foot)	0.751	0.249
Z95.0 Presence of cardiac pacemaker	0.751	0.249
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.751	0.249
N99-N99 Other disorders of the genitourinary system	0.750	0.250
M10 Gout	0.749	0.251
N39 Other disorders of urinary system	0.748	0.252
I05-I09 Chronic rheumatic heart diseases	0.748	0.252
S81 Open wound of lower leg	0.746	0.254
D14 Benign neoplasm of middle ear and respiratory system	0.746	0.254
B95-B98 Bacterial, viral and other infectious agents	0.746	0.254
H80-H83 Diseases of inner ear	0.743	0.257
Z86.0 Personal history of other neoplasms	0.743	0.257
C44.7 Skin of lower limb, including hip	0.741	0.259
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.741	0.259
Chapter VII Diseases of the eye and adnexa	0.741	0.259
S02 Fracture of skull and facial bones	0.739	0.261
E04 Other non-toxic goitre	0.739	0.261
E40-E46 Malnutrition	0.738	0.262
I46 Cardiac arrest	0.737	0.263
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.737	0.263
Z72 Problems related to lifestyle	0.737	0.263
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.736	0.264
F43 Reaction to severe stress, and adjustment disorders	0.735	0.265
S72 Fracture of femur	0.734	0.266
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.734	0.266
Z98.2 Presence of cerebrospinal fluid drainage device	0.732	0.268
S01.8 Open wound of other parts of head	0.731	0.269
I38 Endocarditis, valve unspecified	0.731	0.269
D33 Benign neoplasm of brain and other parts of central nervous system	0.731	0.269
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.731	0.269
I50 Heart failure	0.731	0.269
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.731	0.269
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.730	0.270
M40-M43 Deforming dorsopathies	0.730	0.270
Chapter XXII Codes for special purposes	0.730	0.270
I60-I69 Cerebrovascular diseases	0.729	0.271
N85 Other noninflammatory disorders of uterus, except cervix	0.729	0.271
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.729	0.271
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.728	0.272
C53 Malignant neoplasm of cervix uteri	0.728	0.272
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.727	0.273
S66 Injury of muscle and tendon at wrist and hand level	0.726	0.274
D80-D89 Certain disorders involving the immune mechanism	0.725	0.275
C64-C68 Malignant neoplasms of urinary tract	0.724	0.276
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.724	0.276
V18.0 Driver injured in nontraffic accident	0.723	0.277
M86-M90 Other osteopathies	0.722	0.278
M25.56 Pain in joint (Lower leg)	0.722	0.278
Z90.3 Acquired absence of part of stomach	0.721	0.279
T43.3 Phenothiazine antipsychotics and neuroleptics	0.720	0.280
D27 Benign neoplasm of ovary	0.718	0.282
C79.9 Secondary malignant neoplasm, unspecified site	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
W20-W49 Exposure to inanimate mechanical forces	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I44 Atrioventricular and left bundle-branch block	0.717	0.283
S60 Superficial injury of wrist and hand	0.716	0.283
Z93.0 Tracheostomy status	0.716	0.284
D22 Melanocytic naevi	0.716	0.284
M91-M94 Chondropathies	0.716	0.284
M60-M63 Disorders of muscles	0.716	0.284
M00-M03 Infectious arthropathies	0.716	0.284
I10 Essential (primary) hypertension	0.716	0.284
I72 Other aneurysm	0.716	0.284
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.716	0.284
M21 Other acquired deformities of limbs	0.715	0.285
Z54 Convalescence	0.714	0.285
Z49 Care involving dialysis	0.714	0.285
Z44 Fitting and adjustment of external prosthetic device	0.714	0.285
F99-F99 Unspecified mental disorder	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F80-F89 Disorders of psychological development	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
F60-F69 Disorders of adult personality and behaviour	0.714	0.286
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.714	0.286
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.713	0.287
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.713	0.287
I74 Arterial embolism and thrombosis	0.713	0.287
C79.7 Secondary malignant neoplasm of adrenal gland	0.713	0.287
S64 Injury of nerves at wrist and hand level	0.712	0.287
F32.1 Moderate depressive episode	0.712	0.288
H65 Nonsuppurative otitis media	0.712	0.288
M80-M85 Disorders of bone density and structure	0.712	0.288
M53 Other dorsopathies, not elsewhere classified	0.711	0.289
D11 Benign neoplasm of major salivary glands	0.711	0.289
S20-S29 Injuries to the thorax	0.710	0.290
I77.6 Arteritis, unspecified	0.710	0.290
S61 Open wound of wrist and hand	0.709	0.291
Z86.5 Personal history of other mental and behavioural disorders	0.709	0.291
Z97 Presence of other devices	0.709	0.291
Z89 Acquired absence of limb	0.709	0.291
Z84 Family history of other conditions	0.709	0.291
Z81 Family history of mental and behavioural disorders	0.709	0.291
E06 Thyroiditis	0.708	0.292
T43.0 Tricyclic and tetracyclic antidepressants	0.708	0.292
C44.2 Skin of ear and external auricular canal	0.707	0.293
I00-I02 Acute rheumatic fever	0.706	0.294
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.705	0.294
M34 Systemic sclerosis	0.705	0.294
M33 Dermatopolymyositis	0.705	0.294
M32 Systemic lupus erythematosus	0.705	0.294
M30 Polyarteritis nodosa and related conditions	0.705	0.294
H60-H62 Diseases of external ear	0.705	0.295
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.705	0.295
T15-T19 Effects of foreign body entering through natural orifice	0.704	0.295
I70 Atherosclerosis	0.704	0.296
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.703	0.296
Z46 Fitting and adjustment of other devices	0.703	0.297
F33 Recurrent depressive disorder	0.703	0.297
M54.3 Sciatica	0.703	0.297
I34 Nonrheumatic mitral valve disorders	0.702	0.298
N60.8 Other benign mammary dysplasias	0.702	0.298
H93 Other disorders of ear, not elsewhere classified	0.702	0.298
F38 Other mood [affective] disorders	0.700	0.300
F34 Persistent mood [affective] disorders	0.700	0.300
F30 Manic episode	0.700	0.300
F39 Unspecified mood [affective] disorder	0.700	0.300
R07.4 Chest pain, unspecified	0.699	0.301
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.699	0.301
T84.2 Mechanical complication of internal fixation device of other bones	0.699	0.301
E50-E64 Other nutritional deficiencies	0.699	0.301
Z93.2 Ileostomy status	0.698	0.301
C44.6 Skin of upper limb, including shoulder	0.698	0.302
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.697	0.302
H70 Mastoiditis and related conditions	0.697	0.302
H69 Other disorders of Eustachian tube	0.697	0.302
H68 Eustachian salpingitis and obstruction	0.697	0.302
H67 Otitis media in diseases classified elsewhere	0.697	0.302
N13.3 Other and unspecified hydronephrosis	0.697	0.303
N60.2 Fibroadenosis of breast	0.696	0.303
N85.2 Hypertrophy of uterus	0.695	0.305
H40-H42 Glaucoma	0.694	0.306
E10-E14 Diabetes mellitus	0.694	0.306
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.693	0.307
H94 Other disorders of ear in diseases classified elsewhere	0.693	0.307
H92 Otalgia and effusion of ear	0.693	0.307
D25.1 Intramural leiomyoma of uterus	0.693	0.307
R30-R39 Symptoms and signs involving the urinary system	0.693	0.307
D60-D64 Aplastic and other anaemias	0.692	0.308
T82.1 Mechanical complication of cardiac electronic device	0.691	0.309
M24 Other specific joint derangements	0.691	0.309
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.691	0.309
N39.3 Stress incontinence	0.691	0.309
M25.9 Joint disorder, unspecified	0.690	0.310
M25.8 Other specified joint disorders	0.690	0.310
M25.6 Stiffness of joint, not elsewhere classified	0.690	0.310
M25.3 Other instability of joint	0.690	0.310
M25.2 Flail joint	0.690	0.310
M25.1 Fistula of joint	0.690	0.310
M25.0 Haemarthrosis	0.690	0.310
T43.2 Other and unspecified antidepressants	0.690	0.310
Z90.0 Acquired absence of part of head and neck	0.689	0.310
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.689	0.311
W00-W19 Falls	0.688	0.312
S06.5 Traumatic subdural haemorrhage	0.688	0.312
Z86.1 Personal history of infectious and parasitic diseases	0.688	0.312
H90.0 Conductive hearing loss, bilateral	0.688	0.312
F45 Somatoform disorders	0.688	0.312
M05 Seropositive rheumatoid arthritis	0.687	0.313
X60-X84 Intentional self-harm	0.686	0.314
M25.54 Pain in joint (Hand)	0.685	0.314
F32.8 Other depressive episodes	0.685	0.315
F32.2 Severe depressive episode without psychotic symptoms	0.685	0.315
F32.0 Mild depressive episode	0.685	0.315
S89 Other and unspecified injuries of lower leg	0.684	0.316
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.684	0.316
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.684	0.316
Z90.8 Acquired absence of other organs	0.683	0.317
Z93.1 Gastrostomy status	0.682	0.318
M45 Ankylosing spondylitis	0.681	0.319
T87 Complications peculiar to reattachment and amputation	0.680	0.320
T86 Failure and rejection of transplanted organs and tissues	0.680	0.320
T80 Complications following infusion, transfusion and therapeutic injection	0.680	0.320
C76 Malignant neoplasm of other and ill-defined sites	0.680	0.320
I77.8 Other specified disorders of arteries and arterioles	0.679	0.321
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.679	0.321
M22.2 Patellofemoral disorders	0.678	0.322
D00-D09 In situ neoplasms	0.678	0.322
F48 Other neurotic disorders	0.677	0.323
F44 Dissociative [conversion] disorders	0.677	0.323
F42 Obsessive-compulsive disorder	0.677	0.323
Z91 Personal history of risk-factors, not elsewhere classified	0.675	0.325
C56 Malignant neoplasm of ovary	0.673	0.327
Z47 Other orthopaedic follow-up care	0.673	0.327
M25.4 Effusion of joint	0.672	0.328
N70-N77 Inflammatory diseases of female pelvic organs	0.672	0.328
D51 Vitamin B12 deficiency anaemia	0.672	0.328
Z95.2 Presence of prosthetic heart valve	0.671	0.329
R39 Other symptoms and signs involving the urinary system	0.671	0.329
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.670	0.330
E00 Congenital iodine-deficiency syndrome	0.670	0.330
E02 Subclinical iodine-deficiency hypothyroidism	0.670	0.330
M47 Spondylosis	0.669	0.331
I15 Secondary hypertension	0.669	0.331
I13 Hypertensive heart and renal disease	0.669	0.331
I11 Hypertensive heart disease	0.669	0.331
I12.9 Hypertensive renal disease without renal failure	0.668	0.332
D31 Benign neoplasm of eye and adnexa	0.668	0.332
D30 Benign neoplasm of urinary organs	0.668	0.332
D29 Benign neoplasm of male genital organs	0.668	0.332
D28 Benign neoplasm of other and unspecified female genital organs	0.668	0.332
D26 Other benign neoplasms of uterus	0.668	0.332
D21 Other benign neoplasms of connective and other soft tissue	0.668	0.332
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.668	0.332
D19 Benign neoplasm of mesothelial tissue	0.668	0.332
D16 Benign neoplasm of bone and articular cartilage	0.668	0.332
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.668	0.332
D10 Benign neoplasm of mouth and pharynx	0.668	0.332
M31 Other necrotising vasculopathies	0.668	0.332
S80 Superficial injury of lower leg	0.668	0.332
Y60-Y69 Misadventures to patients during surgical and medical care	0.667	0.333
H90.5 Sensorineural hearing loss, unspecified	0.667	0.333
N85.0 Endometrial glandular hyperplasia	0.667	0.333
C79.6 Secondary malignant neoplasm of ovary	0.667	0.333
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.667	0.333
C79.2 Secondary malignant neoplasm of skin	0.667	0.333
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.667	0.333
T43.5 Other and unspecified antipsychotics and neuroleptics	0.667	0.333
S69 Other and unspecified injuries of wrist and hand	0.665	0.335
S67 Crushing injury of wrist and hand	0.665	0.335
S65 Injury of blood vessels at wrist and hand level	0.665	0.335
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.665	0.335
Y35-Y36 Legal intervention and operations of war	0.665	0.335
Y10-Y34 Event of undetermined intent	0.665	0.335
Y00-Y09 Assault	0.665	0.335
X85-X99 Assault	0.665	0.335
X58-X59 Accidental exposure to other and unspecified factors	0.665	0.335
X50-X57 Overexertion, travel and privation	0.665	0.335
X40-X49 Accidental poisoning by and exposure to noxious substances	0.665	0.335
X30-X39 Exposure to forces of nature	0.665	0.335
X20-X29 Contact with venomous animals and plants	0.665	0.335
X10-X19 Contact with heat and hot substances	0.665	0.335
X00-X09 Exposure to smoke, fire and flames	0.665	0.335
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.665	0.335
W75-W84 Other accidental threats to breathing	0.665	0.335
W65-W74 Accidental drowning and submersion	0.665	0.335
W50-W64 Exposure to animate mechanical forces	0.665	0.335
V98-V99 Other and unspecified transport accidents	0.665	0.335
V95-V97 Air and space transport accidents	0.665	0.335
V90-V94 Water transport accidents	0.665	0.335
V80-V89 Other land transport accidents	0.665	0.335
V70-V79 Bus occupant injured in transport accident	0.665	0.335
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.665	0.335
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.665	0.335
V40-V49 Car occupant injured in transport accident	0.665	0.335
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.665	0.335
V20-V29 Motorcycle rider injured in transport accident	0.665	0.335
V01-V09 Pedestrian injured in transport accident	0.665	0.335
Z93.9 Artificial opening status, unspecified	0.665	0.335
Z93.8 Other artificial opening status	0.665	0.335
Z93.5 Cystostomy status	0.665	0.335
Z93.4 Other artificial openings of gastro-intestinal tract status	0.665	0.335
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.665	0.335
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.665	0.335
E07 Other disorders of thyroid	0.664	0.336
F31.9 Bipolar affective disorder, unspecified	0.663	0.337
D36 Benign neoplasm of other and unspecified sites	0.663	0.337
H74.8 Other specified disorders of middle ear and mastoid	0.662	0.338
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.662	0.338
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.661	0.339
H91.8 Other specified hearing loss	0.661	0.339
H91.3 Deaf mutism, not elsewhere classified	0.661	0.339
H91.2 Sudden idiopathic hearing loss	0.661	0.339
H91.1 Presbycusis	0.661	0.339
H91.0 Ototoxic hearing loss	0.661	0.339
H40 Glaucoma	0.661	0.339
C57 Malignant neoplasm of other and unspecified female genital organs	0.661	0.339
C51 Malignant neoplasm of vulva	0.661	0.339
C58 Malignant neoplasm of placenta	0.661	0.339
C55 Malignant neoplasm of uterus, part unspecified	0.661	0.339
C52 Malignant neoplasm of vagina	0.661	0.339
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.661	0.339
M06.9 Rheumatoid arthritis, unspecified	0.661	0.339
C80 Malignant neoplasm without specification of site	0.661	0.339
M35 Other systemic involvement of connective tissue	0.658	0.341
I50.9 Heart failure, unspecified	0.659	0.341
I49.0 Ventricular fibrillation and flutter	0.658	0.341
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.658	0.342
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.658	0.342
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.658	0.342
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.658	0.342
T46 Poisoning by agents primarily affecting the cardiovascular system	0.658	0.342
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.658	0.342
T41 Poisoning by anaesthetics and therapeutic gases	0.658	0.342
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.658	0.342
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.658	0.342
T36 Poisoning by systemic antibiotics	0.658	0.342
K80 Cholelithiasis	0.658	0.342
N62 Hypertrophy of breast	0.658	0.342
S88 Traumatic amputation of lower leg	0.658	0.342
S87 Crushing injury of lower leg	0.658	0.342
S86 Injury of muscle and tendon at lower leg level	0.658	0.342
S85 Injury of blood vessels at lower leg level	0.658	0.342
S84 Injury of nerves at lower leg level	0.658	0.342
Z52.4 Kidney donor	0.657	0.342
M25.59 Pain in joint (Site unspecified)	0.656	0.343
M25.58 Pain in joint (Other)	0.656	0.343
M25.52 Pain in joint (Upper arm)	0.656	0.343
M25.50 Pain in joint (Multiple sites)	0.656	0.343
S01.1 Open wound of eyelid and periocular area	0.656	0.344
E23 Hypofunction and other disorders of pituitary gland	0.656	0.344
E03.8 Other specified hypothyroidism	0.655	0.345
E03.5 Myxoedema coma	0.655	0.345
E03.4 Atrophy of thyroid (acquired)	0.655	0.345
E03.3 Postinfectious hypothyroidism	0.655	0.345
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.655	0.345
E03.1 Congenital hypothyroidism without goitre	0.655	0.345
E03.0 Congenital hypothyroidism with diffuse goitre	0.655	0.345
M20.3 Other deformity of hallux (acquired)	0.655	0.345
M20.0 Deformity of finger(s)	0.655	0.345
E66 Obesity	0.654	0.346
S82.6 Fracture of lateral malleolus	0.654	0.346
D55-D59 Haemolytic anaemias	0.653	0.347
K85 Acute pancreatitis	0.652	0.348
Z88.0 Personal history of allergy to penicillin	0.652	0.348
M20.2 Hallux rigidus	0.652	0.348
M10.9 Gout, unspecified	0.652	0.348
D34 Benign neoplasm of thyroid gland	0.652	0.348
Z40 Prophylactic surgery	0.651	0.349
N60.4 Mammary duct ectasia	0.650	0.349
T83.0 Mechanical complication of urinary (indwelling) catheter	0.650	0.349
M46 Other inflammatory spondylopathies	0.650	0.350
S62.6 Fracture of other finger	0.650	0.350
T68 Hypothermia	0.649	0.351
S68 Traumatic amputation of wrist and hand	0.649	0.351

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations