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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75054437
log Bayes Factor = 14.0397
Chromosome 5   position 32,892,453  (GRCh37) Explore rs75054437 on Ensembl!
Variant rs75054437 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
D10-D36 Benign neoplasms
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I10-I15 Hypertensive diseases
0.999 0.001 0.000
I10 Essential (primary) hypertension
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
D12.8 Rectum
0.994 0.006 0.000
J40-J47 Chronic lower respiratory diseases
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
J44 Other chronic obstructive pulmonary disease
0.985 0.015 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.969 0.031 0.000
S00-S09 Injuries to the head
0.968 0.032 0.000
Chapter XIV Diseases of the genitourinary system
0.964 0.036 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.964 0.036 0.000
H25-H28 Disorders of lens
0.955 0.045 0.000
I30-I52 Other forms of heart disease
0.953 0.047 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.949 0.051 0.000
M05-M14 Inflammatory polyarthropathies
0.948 0.052 0.000
D12.6 Colon, unspecified
0.944 0.056 0.000
E14 Unspecified diabetes mellitus
0.941 0.059 0.000
Z93 Artificial opening status
0.936 0.064 0.000
Z86 Personal history of certain other diseases
0.935 0.065 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.933 0.067 0.000
M06 Other rheumatoid arthritis
0.933 0.067 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.933 0.067 0.000
D12.2 Ascending colon
0.932 0.068 0.000
D60-D64 Aplastic and other anaemias
0.930 0.070 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.927 0.073 0.000
S00 Superficial injury of head
0.924 0.076 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.923 0.077 0.000
M06.9 Rheumatoid arthritis, unspecified
0.919 0.081 0.000
I05-I09 Chronic rheumatic heart diseases
0.916 0.083 0.000
N25-N29 Other disorders of kidney and ureter
0.916 0.083 0.000
Z80 Family history of malignant neoplasm
0.910 0.090 0.000
D12.5 Sigmoid colon
0.907 0.093 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.904 0.096 0.000
D00-D09 In situ neoplasms
0.902 0.098 0.000
D12.7 Rectosigmoid junction
0.901 0.099 0.000
H25 Senile cataract
0.899 0.101 0.000
C15-C26 Malignant neoplasms of digestive organs
0.899 0.101 0.000
D25 Leiomyoma of uterus
0.897 0.103 0.000
E14.9 Without complications
0.896 0.104 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.893 0.107 0.000
Chapter XX External causes of morbidity and mortality
0.887 0.113 0.000
I47 Paroxysmal tachycardia
0.886 0.114 0.000
J30-J39 Other diseases of upper respiratory tract
0.883 0.117 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.883 0.117 0.000
H26 Other cataract
0.882 0.118 0.000
N17-N19 Renal failure
0.879 0.121 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.879 0.121 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.878 0.122 0.000
D64 Other anaemias
0.877 0.123 0.000
S06 Intracranial injury
0.876 0.124 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.875 0.125 0.000
Z93.2 Ileostomy status
0.873 0.127 0.000
Z86.7 Personal history of diseases of the circulatory system
0.871 0.129 0.000
H25.0 Senile incipient cataract
0.870 0.130 0.000
S50-S59 Injuries to the elbow and forearm
0.870 0.130 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.869 0.131 0.000
J90-J94 Other diseases of pleura
0.869 0.131 0.000
E11 Non-insulin-dependent diabetes mellitus
0.868 0.132 0.000
I12 Hypertensive renal disease
0.867 0.133 0.000
N10-N16 Renal tubulo-interstitial diseases
0.861 0.139 0.000
I08 Multiple valve diseases
0.860 0.140 0.000
S00.8 Superficial injury of other parts of head
0.860 0.140 0.000
Chapter V Mental and behavioural disorders
0.859 0.141 0.000
N99-N99 Other disorders of the genitourinary system
0.859 0.141 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.858 0.142 0.000
Z83 Family history of other specific disorders
0.853 0.147 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.851 0.149 0.000
D12.0 Caecum
0.851 0.149 0.000
D25.9 Leiomyoma of uterus, unspecified
0.851 0.149 0.000
E10 Insulin-dependent diabetes mellitus
0.850 0.150 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.844 0.156 0.000
Z13 Special screening examination for other diseases and disorders
0.844 0.156 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.840 0.160 0.000
D64.9 Anaemia, unspecified
0.839 0.161 0.000
E86 Volume depletion
0.839 0.161 0.000
N19 Unspecified renal failure
0.827 0.173 0.000
Z93.6 Other artificial openings of urinary tract status
0.825 0.175 0.000
D12.3 Transverse colon
0.824 0.176 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.823 0.177 0.000
Z98 Other postsurgical states
0.823 0.177 0.000
N30-N39 Other diseases of urinary system
0.822 0.178 0.000
J42 Unspecified chronic bronchitis
0.821 0.178 0.000
S60-S69 Injuries to the wrist and hand
0.817 0.183 0.000
E00-E07 Disorders of thyroid gland
0.814 0.186 0.000
T79-T79 Certain early complications of trauma
0.813 0.187 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.813 0.187 0.000
J35 Chronic diseases of tonsils and adenoids
0.809 0.191 0.000
H26.4 After-cataract
0.809 0.191 0.000
J90 Pleural effusion, not elsewhere classified
0.808 0.192 0.000
E20-E35 Disorders of other endocrine glands
0.808 0.192 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.808 0.192 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.803 0.197 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.802 0.198 0.000
H25.9 Senile cataract, unspecified
0.801 0.199 0.000
D36 Benign neoplasm of other and unspecified sites
0.799 0.201 0.000
H55-H59 Other disorders of eye and adnexa
0.797 0.203 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.796 0.204 0.000
E11.9 Without complications
0.795 0.205 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.793 0.207 0.000
M80-M85 Disorders of bone density and structure
0.792 0.208 0.000
I50 Heart failure
0.791 0.209 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.791 0.209 0.000
N28.8 Other specified disorders of kidney and ureter
0.790 0.210 0.000
Chapter I Certain infectious and parasitic diseases
0.788 0.212 0.000
Z97 Presence of other devices
0.786 0.214 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.785 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.781 0.219 0.000
M13 Other arthritis
0.780 0.220 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.779 0.221 0.000
M86-M90 Other osteopathies
0.779 0.221 0.000
N13 Obstructive and reflux uropathy
0.778 0.222 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.778 0.222 0.000
E50-E64 Other nutritional deficiencies
0.778 0.222 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.224 0.000
E87.3 Alkalosis
0.775 0.225 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.775 0.225 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.774 0.226 0.000
D12.9 Anus and anal canal
0.773 0.227 0.000
S00.9 Superficial injury of head, part unspecified
0.772 0.228 0.000
M70-M79 Other soft tissue disorders
0.772 0.228 0.000
I45 Other conduction disorders
0.770 0.230 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.767 0.233 0.000
I47.1 Supraventricular tachycardia
0.767 0.233 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.766 0.234 0.000
J95-J99 Other diseases of the respiratory system
0.765 0.235 0.000
H30-H36 Disorders of choroid and retina
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.238 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.762 0.238 0.000
H26.8 Other specified cataract
0.759 0.241 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.758 0.241 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.758 0.242 0.000
J43 Emphysema
0.758 0.242 0.000
N30 Cystitis
0.758 0.242 0.000
N00-N08 Glomerular diseases
0.757 0.243 0.000
N28.1 Cyst of kidney, acquired
0.756 0.244 0.000
S05 Injury of eye and orbit
0.755 0.245 0.000
I08.0 Disorders of both mitral and aortic valves
0.755 0.245 0.000
E87.0 Hyperosmolality and hypernatraemia
0.755 0.245 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.754 0.246 0.000
C25 Malignant neoplasm of pancreas
0.754 0.246 0.000
S02 Fracture of skull and facial bones
0.753 0.247 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.753 0.247 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.753 0.247 0.000
J00-J06 Acute upper respiratory infections
0.752 0.248 0.000
E87.2 Acidosis
0.751 0.249 0.000
E87.5 Hyperkalaemia
0.750 0.250 0.000
D05 Carcinoma in situ of breast
0.749 0.251 0.000
S00.1 Contusion of eyelid and periocular area
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.748 0.252 0.000
I12.0 Hypertensive renal disease with renal failure
0.748 0.252 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.745 0.255 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.257 0.000
I34 Nonrheumatic mitral valve disorders
0.743 0.257 0.000
I33 Acute and subacute endocarditis
0.743 0.257 0.000
D03 Melanoma in situ
0.743 0.257 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.742 0.258 0.000
W00-W19 Falls
0.742 0.258 0.000
J38.3 Other diseases of vocal cords
0.742 0.258 0.000
S52 Fracture of forearm
0.742 0.258 0.000
E14.3 With ophthalmic complications
0.740 0.259 0.000
Z93.3 Colostomy status
0.740 0.260 0.000
H27 Other disorders of lens
0.740 0.260 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.739 0.261 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.738 0.262 0.000
J40 Bronchitis, not specified as acute or chronic
0.738 0.262 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.738 0.262 0.000
D62 Acute posthaemorrhagic anaemia
0.736 0.264 0.000
I47.0 Reentry ventricular arrhythmia
0.736 0.264 0.000
E13 Other specified diabetes mellitus
0.735 0.265 0.000
I31 Other diseases of pericardium
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.734 0.265 0.000
T43.2 Other and unspecified antidepressants
0.734 0.266 0.000
D32 Benign neoplasm of meninges
0.734 0.266 0.000
Z83.3 Family history of diabetes mellitus
0.734 0.266 0.000
M05 Seropositive rheumatoid arthritis
0.734 0.266 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.732 0.267 0.000
D10 Benign neoplasm of mouth and pharynx
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.732 0.268 0.000
Z98.8 Other specified postsurgical states
0.730 0.270 0.000
M06.0 Seronegative rheumatoid arthritis
0.729 0.271 0.000
Z80.3 Family history of malignant neoplasm of breast
0.728 0.272 0.000
S06.5 Traumatic subdural haemorrhage
0.726 0.274 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.726 0.274 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.725 0.275 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.724 0.275 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.724 0.276 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.722 0.278 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.722 0.278 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.722 0.278 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.722 0.278 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.280 0.000
J46 Status asthmaticus
0.720 0.280 0.000
Z12 Special screening examination for neoplasms
0.720 0.280 0.000
H43-H45 Disorders of vitreous body and globe
0.719 0.280 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D12.1 Appendix
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
D31 Benign neoplasm of eye and adnexa
0.717 0.283 0.000
D30 Benign neoplasm of urinary organs
0.717 0.283 0.000
D29 Benign neoplasm of male genital organs
0.717 0.283 0.000
D26 Other benign neoplasms of uterus
0.717 0.283 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.717 0.283 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.717 0.283 0.000
D19 Benign neoplasm of mesothelial tissue
0.717 0.283 0.000
D16 Benign neoplasm of bone and articular cartilage
0.717 0.283 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I15 Secondary hypertension
0.716 0.284 0.000
I13 Hypertensive heart and renal disease
0.716 0.284 0.000
I11 Hypertensive heart disease
0.716 0.284 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.716 0.284 0.000
I47.2 Ventricular tachycardia
0.716 0.284 0.000
C15 Malignant neoplasm of oesophagus
0.715 0.285 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.714 0.286 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.709 0.291 0.000
E87.7 Fluid overload
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.708 0.292 0.000
W20-W49 Exposure to inanimate mechanical forces
0.707 0.293 0.000
D04 Carcinoma in situ of skin
0.707 0.293 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.293 0.000
D80-D89 Certain disorders involving the immune mechanism
0.706 0.293 0.000
Z86.0 Personal history of other neoplasms
0.706 0.294 0.000
S70-S79 Injuries to the hip and thigh
0.705 0.295 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.704 0.296 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.704 0.296 0.000
J35.0 Chronic tonsillitis
0.703 0.297 0.000
I49 Other cardiac arrhythmias
0.703 0.297 0.000
Z89 Acquired absence of limb
0.702 0.297 0.000
Z84 Family history of other conditions
0.702 0.297 0.000
Z81 Family history of mental and behavioural disorders
0.702 0.297 0.000
H10-H13 Disorders of conjunctiva
0.702 0.298 0.000
C20 Malignant neoplasm of rectum
0.701 0.299 0.000
Z93.0 Tracheostomy status
0.701 0.299 0.000
Z92 Personal history of medical treatment
0.701 0.299 0.000
E10.5 With peripheral circulatory complications
0.701 0.299 0.000
Z90.5 Acquired absence of kidney
0.698 0.302 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.303 0.000
M45-M49 Spondylopathies
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.697 0.303 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.695 0.305 0.000
E88 Other metabolic disorders
0.695 0.305 0.000
E85 Amyloidosis
0.695 0.305 0.000
E84 Cystic fibrosis
0.695 0.305 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.695 0.305 0.000
E79 Disorders of purine and pyrimidine metabolism
0.695 0.305 0.000
E77 Disorders of glycoprotein metabolism
0.695 0.305 0.000
E76 Disorders of glycosaminoglycan metabolism
0.695 0.305 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.695 0.305 0.000
E74 Other disorders of carbohydrate metabolism
0.695 0.305 0.000
E73 Lactose intolerance
0.695 0.305 0.000
E72 Other disorders of amino-acid metabolism
0.695 0.305 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.695 0.305 0.000
E70 Disorders of aromatic amino-acid metabolism
0.695 0.305 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.695 0.305 0.000
C51-C58 Malignant neoplasms of female genital organs
0.695 0.305 0.000
H18 Other disorders of cornea
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.694 0.306 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.694 0.306 0.000
S07 Crushing injury of head
0.694 0.306 0.000
S04 Injury of cranial nerves
0.694 0.306 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.694 0.306 0.000
D45 Polycythaemia vera
0.694 0.306 0.000
S51 Open wound of forearm
0.693 0.307 0.000
I46 Cardiac arrest
0.693 0.307 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.693 0.307 0.000
I95 Hypotension
0.692 0.308 0.000
E10.3 With ophthalmic complications
0.692 0.308 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.691 0.309 0.000
D68 Other coagulation defects
0.691 0.309 0.000
M65-M68 Disorders of synovium and tendon
0.690 0.310 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.689 0.311 0.000
J60-J70 Lung diseases due to external agents
0.688 0.312 0.000
C50-C50 Malignant neoplasm of breast
0.688 0.312 0.000
S52.6 Fracture of lower end of both ulna and radius
0.687 0.313 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.686 0.314 0.000
I30 Acute pericarditis
0.685 0.314 0.000
I35 Nonrheumatic aortic valve disorders
0.685 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.685 0.315 0.000
H26.1 Traumatic cataract
0.685 0.315 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.685 0.315 0.000
H35 Other retinal disorders
0.685 0.315 0.000
I52 Other heart disorders in diseases classified elsewhere
0.683 0.317 0.000
I48 Atrial fibrillation and flutter
0.683 0.317 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.683 0.317 0.000
I41 Myocarditis in diseases classified elsewhere
0.683 0.317 0.000
I40 Acute myocarditis
0.683 0.317 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.683 0.317 0.000
I37 Pulmonary valve disorders
0.683 0.317 0.000
I36 Nonrheumatic tricuspid valve disorders
0.683 0.317 0.000
I32 Pericarditis in diseases classified elsewhere
0.683 0.317 0.000
I38 Endocarditis, valve unspecified
0.683 0.317 0.000
E11.6 With other specified complications
0.682 0.318 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.682 0.318 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.682 0.318 0.000
J37 Chronic laryngitis and laryngotracheitis
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.320 0.000
E10.2 With renal complications
0.680 0.320 0.000
C64-C68 Malignant neoplasms of urinary tract
0.680 0.320 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.680 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.680 0.320 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.680 0.320 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.680 0.320 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.680 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.680 0.320 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
T36 Poisoning by systemic antibiotics
0.680 0.320 0.000
E78.5 Hyperlipidaemia, unspecified
0.680 0.320 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.680 0.320 0.000
M14 Arthropathies in other diseases classified elsewhere
0.680 0.320 0.000
M12 Other specific arthropathies
0.680 0.320 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.680 0.320 0.000
M08 Juvenile arthritis
0.680 0.320 0.000
A30-A49 Other bacterial diseases
0.678 0.322 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.677 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
D11 Benign neoplasm of major salivary glands
0.677 0.323 0.000
M50-M54 Other dorsopathies
0.677 0.323 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.675 0.325 0.000
E27 Other disorders of adrenal gland
0.675 0.325 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.674 0.325 0.000
E14.8 With unspecified complications
0.674 0.326 0.000
E14.7 With multiple complications
0.674 0.326 0.000
E14.6 With other specified complications
0.674 0.326 0.000
E14.5 With peripheral circulatory complications
0.674 0.326 0.000
E14.4 With neurological complications
0.674 0.326 0.000
E14.2 Withrenal complications
0.674 0.326 0.000
E14.1 With ketoacidosis
0.674 0.326 0.000
E14.0 With coma
0.674 0.326 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.674 0.326 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.673 0.326 0.000
D46 Myelodysplastic syndromes
0.673 0.326 0.000
E53 Deficiency of other B group vitamins
0.673 0.327 0.000
E07 Other disorders of thyroid
0.673 0.327 0.000
Z94 Transplanted organ and tissue status
0.671 0.328 0.000
H40-H42 Glaucoma
0.671 0.329 0.000
Z93.9 Artificial opening status, unspecified
0.671 0.329 0.000
Z93.8 Other artificial opening status
0.671 0.329 0.000
Z93.5 Cystostomy status
0.671 0.329 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.671 0.329 0.000
I12.9 Hypertensive renal disease without renal failure
0.671 0.329 0.000
J47 Bronchiectasis
0.670 0.330 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.670 0.330 0.000
Z10 Routine general health check-up of defined subpopulation
0.669 0.331 0.000
M06.8 Other specified rheumatoid arthritis
0.669 0.331 0.000
M06.4 Inflammatory polyarthropathy
0.669 0.331 0.000
M06.3 Rheumatoid nodule
0.669 0.331 0.000
M06.2 Rheumatoid bursitis
0.669 0.331 0.000
M06.1 Adult-onset Still's disease
0.669 0.331 0.000
D12.4 Descending colon
0.667 0.333 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.667 0.333 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.667 0.333 0.000
Z97.8 Presence of other specified devices
0.667 0.333 0.000
T42.4 Benzodiazepines
0.666 0.334 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.666 0.334 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.666 0.334 0.000
M11 Other crystal arthropathies
0.665 0.335 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.665 0.335 0.000
E87.4 Mixed disorder of acid-base balance
0.665 0.335 0.000
Z95.1 Presence of aortocoronary bypass graft
0.663 0.337 0.000
S00.7 Multiple superficial injuries of head
0.663 0.337 0.000
S00.5 Superficial injury of lip and oral cavity
0.663 0.337 0.000
S00.4 Superficial injury of ear
0.663 0.337 0.000
S00.3 Superficial injury of nose
0.663 0.337 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.662 0.338 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.661 0.339 0.000
S40-S49 Injuries to the shoulder and upper arm
0.660 0.340 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.660 0.340 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.660 0.340 0.000
Z83.5 Family history of eye and ear disorders
0.659 0.341 0.000
M81 Osteoporosis without pathological fracture
0.659 0.341 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.659 0.341 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.659 0.341 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.659 0.341 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.659 0.341 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.659 0.341 0.000
J30 Vasomotor and allergic rhinitis
0.659 0.341 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.657 0.342 0.000
I09 Other rheumatic heart diseases
0.657 0.343 0.000
I06 Rheumatic aortic valve diseases
0.657 0.343 0.000
I05 Rheumatic mitral valve diseases
0.657 0.343 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.657 0.343 0.000
N27 Small kidney of unknown cause
0.657 0.343 0.000
N25 Disorders resulting from impaired renal tubular function
0.657 0.343 0.000
N26 Unspecified contracted kidney
0.657 0.343 0.000
N30.8 Other cystitis
0.657 0.343 0.000
D63.0 Anaemia in neoplastic disease
0.657 0.343 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.657 0.343 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.656 0.344 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.655 0.345 0.000
C18 Malignant neoplasm of colon
0.655 0.345 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.654 0.346 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.653 0.347 0.000
Z80.6 Family history of leukaemia
0.653 0.347 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.653 0.347 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.652 0.348 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.652 0.348 0.000
E04 Other non-toxic goitre
0.652 0.348 0.000
Z02 Examination and encounter for administrative purposes
0.651 0.349 0.000
I51 Complications and ill-defined descriptions of heart disease
0.651 0.349 0.000
S61 Open wound of wrist and hand
0.650 0.350 0.000
N18 Chronic renal failure
0.650 0.350 0.000
H17 Corneal scars and opacities
0.650 0.350 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.649 0.351 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.648 0.352 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.648 0.352 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.647 0.352 0.000
J36 Peritonsillar abscess
0.647 0.353 0.000
D09 Carcinoma in situ of other and unspecified sites
0.646 0.353 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.646 0.353 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.646 0.353 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.646 0.353 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.646 0.354 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.646 0.354 0.000
H25.2 Senile cataract, morgagnian type
0.645 0.355 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.644 0.355 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.644 0.355 0.000
C21 Malignant neoplasm of anus and anal canal
0.644 0.355 0.000
C17 Malignant neoplasm of small intestine
0.644 0.355 0.000
C23 Malignant neoplasm of gallbladder
0.644 0.355 0.000
D25.0 Submucous leiomyoma of uterus
0.644 0.356 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.644 0.356 0.000
N99.1 Postprocedural urethral stricture
0.644 0.356 0.000
S06.2 Diffuse brain injury
0.643 0.356 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.643 0.357 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.643 0.357 0.000
I07 Rheumatic tricuspid valve diseases
0.642 0.358 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.641 0.359 0.000
E11.3 With ophthalmic complications
0.641 0.359 0.000
D75 Other diseases of blood and blood-forming organs
0.641 0.359 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.640 0.360 0.000
M07 Psoriatic and enteropathic arthropathies
0.639 0.361 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.638 0.361 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.638 0.362 0.000
M10 Gout
0.637 0.363 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.636 0.364 0.000
Y35-Y36 Legal intervention and operations of war
0.636 0.364 0.000
Y10-Y34 Event of undetermined intent
0.636 0.364 0.000
Y00-Y09 Assault
0.636 0.364 0.000
X85-X99 Assault
0.636 0.364 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.636 0.364 0.000
X50-X57 Overexertion, travel and privation
0.636 0.364 0.000
X30-X39 Exposure to forces of nature
0.636 0.364 0.000
X20-X29 Contact with venomous animals and plants
0.636 0.364 0.000
X10-X19 Contact with heat and hot substances
0.636 0.364 0.000
X00-X09 Exposure to smoke, fire and flames
0.636 0.364 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.636 0.364 0.000
W75-W84 Other accidental threats to breathing
0.636 0.364 0.000
W65-W74 Accidental drowning and submersion
0.636 0.364 0.000
W50-W64 Exposure to animate mechanical forces
0.636 0.364 0.000
V98-V99 Other and unspecified transport accidents
0.636 0.364 0.000
V95-V97 Air and space transport accidents
0.636 0.364 0.000
V90-V94 Water transport accidents
0.636 0.364 0.000
V80-V89 Other land transport accidents
0.636 0.364 0.000
V70-V79 Bus occupant injured in transport accident
0.636 0.364 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.636 0.364 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.636 0.364 0.000
V40-V49 Car occupant injured in transport accident
0.636 0.364 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.636 0.364 0.000
V01-V09 Pedestrian injured in transport accident
0.636 0.364 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.635 0.365 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.635 0.365 0.000
M13.0 Polyarthritis, unspecified
0.635 0.365 0.000
N30.3 Trigonitis
0.635 0.365 0.000
N28.0 Ischaemia and infarction of kidney
0.633 0.367 0.000
H26.3 Drug-induced cataract
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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