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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75066253
log Bayes Factor = 12.2054
Chromosome 1   position 39,214,067  (GRCh37) Explore rs75066253 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
I44.7 Left bundle-branch block, unspecified
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
I51 Complications and ill-defined descriptions of heart disease
0.992 0.008 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
I50 Heart failure
0.984 0.016 0.000
F32 Depressive episode
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
N00-N08 Glomerular diseases
0.981 0.019 0.000
F31 Bipolar affective disorder
0.977 0.023 0.000
H65-H75 Diseases of middle ear and mastoid
0.975 0.025 0.000
I51.8 Other ill-defined heart diseases
0.975 0.025 0.000
F32.9 Depressive episode, unspecified
0.974 0.026 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.969 0.031 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.966 0.034 0.000
N10-N16 Renal tubulo-interstitial diseases
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
I50.1 Left ventricular failure
0.954 0.046 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.952 0.048 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.945 0.055 0.000
N25-N29 Other disorders of kidney and ureter
0.941 0.059 0.000
Y83.6 Removal of other organ (partial) (total)
0.938 0.062 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.931 0.069 0.000
I95 Hypotension
0.925 0.075 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.922 0.078 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.918 0.082 0.000
I51.9 Heart disease, unspecified
0.916 0.084 0.000
I34 Nonrheumatic mitral valve disorders
0.912 0.088 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.911 0.089 0.000
H72 Perforation of tympanic membrane
0.910 0.090 0.000
A00-A09 Intestinal infectious diseases
0.910 0.090 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.897 0.103 0.000
N60-N64 Disorders of breast
0.893 0.107 0.000
A30-A49 Other bacterial diseases
0.893 0.107 0.000
I35 Nonrheumatic aortic valve disorders
0.889 0.111 0.000
H69 Other disorders of Eustachian tube
0.887 0.113 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.883 0.117 0.000
T51 Toxic effect of alcohol
0.881 0.118 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.879 0.121 0.000
A04 Other bacterial intestinal infections
0.878 0.122 0.000
N03 Chronic nephritic syndrome
0.875 0.125 0.000
B25-B34 Other viral diseases
0.875 0.125 0.000
F03 Unspecified dementia
0.873 0.127 0.000
I47 Paroxysmal tachycardia
0.872 0.128 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.872 0.128 0.000
F31.9 Bipolar affective disorder, unspecified
0.871 0.129 0.000
N13 Obstructive and reflux uropathy
0.870 0.130 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.866 0.134 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.863 0.137 0.000
I95.1 Orthostatic hypotension
0.862 0.138 0.000
I34.0 Mitral (valve) insufficiency
0.860 0.140 0.000
O80-O84 Delivery
0.859 0.141 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.857 0.143 0.000
Y83.3 Surgical operation with formation of external stoma
0.856 0.144 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.853 0.147 0.000
N63 Unspecified lump in breast
0.852 0.148 0.000
H60-H62 Diseases of external ear
0.851 0.148 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.848 0.152 0.000
I33 Acute and subacute endocarditis
0.848 0.152 0.000
I99 Other and unspecified disorders of circulatory system
0.846 0.154 0.000
O60-O75 Complications of labour and delivery
0.845 0.155 0.000
Y83.0 Surgical operation with transplant of whole organ
0.844 0.156 0.000
S90-S99 Injuries to the ankle and foot
0.843 0.157 0.000
I10-I15 Hypertensive diseases
0.843 0.157 0.000
I46 Cardiac arrest
0.838 0.162 0.000
B95-B98 Bacterial, viral and other infectious agents
0.838 0.162 0.000
O72 Postpartum haemorrhage
0.837 0.163 0.000
A04.8 Other specified bacterial intestinal infections
0.836 0.164 0.000
O72.1 Other immediate postpartum haemorrhage
0.834 0.166 0.000
T51.0 Ethanol
0.832 0.168 0.000
Y40 Systemic antibiotics
0.832 0.168 0.000
F60-F69 Disorders of adult personality and behaviour
0.828 0.172 0.000
M45-M49 Spondylopathies
0.822 0.178 0.000
I47.2 Ventricular tachycardia
0.821 0.179 0.000
N20-N23 Urolithiasis
0.819 0.180 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
H72.0 Central perforation of tympanic membrane
0.818 0.182 0.000
I50.0 Congestive heart failure
0.817 0.183 0.000
S50-S59 Injuries to the elbow and forearm
0.816 0.184 0.000
B15-B19 Viral hepatitis
0.814 0.186 0.000
I50.9 Heart failure, unspecified
0.812 0.188 0.000
F99-F99 Unspecified mental disorder
0.811 0.189 0.000
B99-B99 Other infectious diseases
0.807 0.193 0.000
T39.1 4-Aminophenol derivatives
0.805 0.195 0.000
N05 Unspecified nephritic syndrome
0.805 0.195 0.000
A41 Other septicaemia
0.804 0.196 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.803 0.197 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.802 0.198 0.000
H73 Other disorders of tympanic membrane
0.802 0.198 0.000
N17-N19 Renal failure
0.802 0.198 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.800 0.200 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.800 0.200 0.000
N03.9 Unspecified
0.800 0.200 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.799 0.201 0.000
I12 Hypertensive renal disease
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.791 0.209 0.000
H80-H83 Diseases of inner ear
0.791 0.209 0.000
B50-B64 Protozoal diseases
0.790 0.209 0.000
T59 Toxic effect of other gases, fumes and vapours
0.790 0.210 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.789 0.211 0.000
O80 Single spontaneous delivery
0.788 0.212 0.000
F70-F79 Mental retardation
0.788 0.212 0.000
Q80-Q89 Other congenital malformations
0.786 0.214 0.000
N13.4 Hydroureter
0.785 0.215 0.000
I95.2 Hypotension due to drugs
0.784 0.216 0.000
B34 Viral infection of unspecified site
0.783 0.217 0.000
B65-B83 Helminthiases
0.782 0.218 0.000
I45 Other conduction disorders
0.782 0.218 0.000
V40-V49 Car occupant injured in transport accident
0.780 0.220 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.779 0.221 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.776 0.224 0.000
I60-I69 Cerebrovascular diseases
0.776 0.224 0.000
W20-W49 Exposure to inanimate mechanical forces
0.775 0.225 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.774 0.225 0.000
M47 Spondylosis
0.774 0.226 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.773 0.227 0.000
I51.4 Myocarditis, unspecified
0.773 0.227 0.000
H66 Suppurative and unspecified otitis media
0.773 0.227 0.000
M05-M14 Inflammatory polyarthropathies
0.772 0.228 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.772 0.228 0.000
I05-I09 Chronic rheumatic heart diseases
0.771 0.229 0.000
I35.8 Other aortic valve disorders
0.771 0.229 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.770 0.230 0.000
T40.2 Other opioids
0.769 0.231 0.000
N64 Other disorders of breast
0.768 0.232 0.000
T58 Toxic effect of carbon monoxide
0.768 0.232 0.000
H69.8 Other specified disorders of Eustachian tube
0.766 0.234 0.000
I67 Other cerebrovascular diseases
0.763 0.237 0.000
I44.3 Other and unspecified atrioventricular block
0.763 0.237 0.000
I51.6 Cardiovascular disease, unspecified
0.762 0.238 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.759 0.241 0.000
H69.9 Eustachian tube disorder, unspecified
0.757 0.243 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.757 0.243 0.000
X20-X29 Contact with venomous animals and plants
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.754 0.246 0.000
F32.1 Moderate depressive episode
0.754 0.246 0.000
N25 Disorders resulting from impaired renal tubular function
0.751 0.249 0.000
I37 Pulmonary valve disorders
0.750 0.250 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.749 0.251 0.000
I67.8 Other specified cerebrovascular diseases
0.749 0.251 0.000
F29 Unspecified nonorganic psychosis
0.748 0.252 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.746 0.254 0.000
F32.0 Mild depressive episode
0.745 0.255 0.000
Chapter VII Diseases of the eye and adnexa
0.743 0.257 0.000
H61 Other disorders of external ear
0.739 0.261 0.000
I33.0 Acute and subacute infective endocarditis
0.739 0.261 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.739 0.261 0.000
N02 Recurrent and persistent haematuria
0.737 0.263 0.000
M47.8 Other spondylosis
0.737 0.263 0.000
W50-W64 Exposure to animate mechanical forces
0.737 0.263 0.000
Y83.5 Amputation of limb(s)
0.736 0.264 0.000
H65 Nonsuppurative otitis media
0.735 0.265 0.000
I30 Acute pericarditis
0.734 0.266 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.732 0.268 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.732 0.268 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.731 0.269 0.000
F02 Dementia in other diseases classified elsewhere
0.730 0.270 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.728 0.272 0.000
M50-M54 Other dorsopathies
0.728 0.272 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.728 0.272 0.000
N26 Unspecified contracted kidney
0.727 0.273 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.726 0.274 0.000
I77 Other disorders of arteries and arterioles
0.726 0.274 0.000
S92 Fracture of foot, except ankle
0.725 0.275 0.000
N04 Nephrotic syndrome
0.725 0.275 0.000
H72.8 Other perforations of tympanic membrane
0.725 0.275 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.722 0.278 0.000
A41.8 Other specified septicaemia
0.722 0.278 0.000
I12.9 Hypertensive renal disease without renal failure
0.721 0.279 0.000
F80-F89 Disorders of psychological development
0.720 0.280 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
S20-S29 Injuries to the thorax
0.716 0.284 0.000
F38 Other mood [affective] disorders
0.716 0.284 0.000
F34 Persistent mood [affective] disorders
0.716 0.284 0.000
F30 Manic episode
0.716 0.284 0.000
F39 Unspecified mood [affective] disorder
0.716 0.284 0.000
Y40.9 Systemic antibiotic, unspecified
0.715 0.285 0.000
I44.5 Left posterior fascicular block
0.714 0.286 0.000
I44.4 Left anterior fascicular block
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
A40 Streptococcal septicaemia
0.712 0.288 0.000
N20 Calculus of kidney and ureter
0.712 0.288 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
I51.5 Myocardial degeneration
0.711 0.289 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.711 0.289 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.711 0.289 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.711 0.289 0.000
I51.0 Cardiac septal defect, acquired
0.711 0.289 0.000
B34.9 Viral infection, unspecified
0.710 0.290 0.000
I31 Other diseases of pericardium
0.710 0.290 0.000
I38 Endocarditis, valve unspecified
0.709 0.291 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
F32.8 Other depressive episodes
0.705 0.295 0.000
I47.0 Reentry ventricular arrhythmia
0.705 0.295 0.000
F60 Specific personality disorders
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.705 0.295 0.000
I44.6 Other and unspecified fascicular block
0.705 0.295 0.000
S70-S79 Injuries to the hip and thigh
0.705 0.295 0.000
Y52 Agents primarily affecting the cardiovascular system
0.705 0.295 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.703 0.297 0.000
N06 Isolated proteinuria with specified morphological lesion
0.703 0.297 0.000
N01 Rapidly progressive nephritic syndrome
0.703 0.297 0.000
N00 Acute nephritic syndrome
0.703 0.297 0.000
H90-H95 Other disorders of ear
0.703 0.297 0.000
Y40.8 Other systemic antibiotics
0.702 0.298 0.000
O80.9 Single spontaneous delivery, unspecified
0.702 0.298 0.000
N64.5 Other signs and symptoms in breast
0.702 0.298 0.000
I35.1 Aortic (valve) insufficiency
0.702 0.298 0.000
I12.0 Hypertensive renal disease with renal failure
0.702 0.298 0.000
O73 Retained placenta and membranes, without haemorrhage
0.702 0.298 0.000
N11 Chronic tubulo-interstitial nephritis
0.701 0.299 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
F31.8 Other bipolar affective disorders
0.700 0.300 0.000
F31.7 Bipolar affective disorder, currently in remission
0.700 0.300 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.700 0.300 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.700 0.300 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.700 0.300 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.700 0.300 0.000
I42 Cardiomyopathy
0.700 0.300 0.000
F33 Recurrent depressive disorder
0.699 0.301 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.699 0.301 0.000
H70 Mastoiditis and related conditions
0.699 0.301 0.000
H68 Eustachian salpingitis and obstruction
0.699 0.301 0.000
H67 Otitis media in diseases classified elsewhere
0.699 0.301 0.000
N10 Acute tubulo-interstitial nephritis
0.699 0.301 0.000
H02 Other disorders of eyelid
0.699 0.301 0.000
N73 Other female pelvic inflammatory diseases
0.698 0.302 0.000
M51 Other intervertebral disk disorders
0.698 0.302 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
I36 Nonrheumatic tricuspid valve disorders
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.692 0.308 0.000
N15 Other renal tubulo-interstitial diseases
0.692 0.308 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.692 0.308 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.691 0.309 0.000
M80-M85 Disorders of bone density and structure
0.689 0.311 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.688 0.312 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.688 0.312 0.000
O82 Single delivery by Caesarean section
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.687 0.313 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.313 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.687 0.313 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.687 0.313 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
T36 Poisoning by systemic antibiotics
0.687 0.313 0.000
I95.9 Hypotension, unspecified
0.686 0.314 0.000
N13.3 Other and unspecified hydronephrosis
0.685 0.315 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.685 0.315 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.685 0.315 0.000
M51.2 Other specified intervertebral disk displacement
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.682 0.318 0.000
H80 Otosclerosis
0.681 0.319 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.681 0.319 0.000
Q85 Phakomatoses, not elsewhere classified
0.680 0.320 0.000
T59.9 Gases, fumes and vapours, unspecified
0.679 0.320 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.320 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
I46.0 Cardiac arrest with successful resuscitation
0.678 0.322 0.000
T79-T79 Certain early complications of trauma
0.678 0.322 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.678 0.322 0.000
H73.8 Other specified disorders of tympanic membrane
0.678 0.322 0.000
M60-M63 Disorders of muscles
0.678 0.322 0.000
H04 Disorders of lachrymal system
0.678 0.322 0.000
T65 Toxic effect of other and unspecified substances
0.678 0.322 0.000
T62 Toxic effect of other noxious substances eaten as food
0.678 0.322 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.678 0.322 0.000
T60 Toxic effect of pesticides
0.678 0.322 0.000
T57 Toxic effect of other inorganic substances
0.678 0.322 0.000
T56 Toxic effect of metals
0.678 0.322 0.000
T54 Toxic effect of corrosive substances
0.678 0.322 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.678 0.322 0.000
T52 Toxic effect of organic solvents
0.678 0.322 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.678 0.322 0.000
T55 Toxic effect of soaps and detergents
0.678 0.322 0.000
Y40.3 Macrolides
0.678 0.322 0.000
M00-M03 Infectious arthropathies
0.677 0.322 0.000
F99 Mental disorder, not otherwise specified
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
I11 Hypertensive heart disease
0.675 0.325 0.000
Q50-Q56 Congenital malformations of genital organs
0.675 0.325 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.675 0.325 0.000
N27 Small kidney of unknown cause
0.675 0.325 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.674 0.326 0.000
I78 Diseases of capillaries
0.673 0.327 0.000
B99 Other and unspecified infectious diseases
0.672 0.328 0.000
F20 Schizophrenia
0.672 0.328 0.000
M86-M90 Other osteopathies
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
N17 Acute renal failure
0.671 0.329 0.000
M47.86 Other spondylosis (Lumbar region)
0.671 0.329 0.000
T39.0 Salicylates
0.669 0.331 0.000
Y54.3 Benzothiadiazine derivatives
0.669 0.331 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.668 0.332 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.668 0.332 0.000
N28.1 Cyst of kidney, acquired
0.668 0.332 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.667 0.333 0.000
F09 Unspecified organic or symptomatic mental disorder
0.667 0.333 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.667 0.333 0.000
Y43 Primarily systemic agents
0.667 0.333 0.000
I46.9 Cardiac arrest, unspecified
0.666 0.334 0.000
N20.0 Calculus of kidney
0.665 0.335 0.000
H02.9 Disorder of eyelid, unspecified
0.664 0.336 0.000
Y83.4 Other reconstructive surgery
0.664 0.336 0.000
I95.8 Other hypotension
0.663 0.336 0.000
I95.0 Idiopathic hypotension
0.663 0.336 0.000
S12 Fracture of neck
0.663 0.337 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.661 0.339 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.661 0.339 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.661 0.339 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.661 0.339 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.661 0.339 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.661 0.339 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.661 0.339 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.660 0.340 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.658 0.342 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.658 0.342 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.658 0.342 0.000
A49 Bacterial infection of unspecified site
0.657 0.343 0.000
H65.4 Other chronic nonsuppurative otitis media
0.657 0.343 0.000
I35.9 Aortic valve disorder, unspecified
0.656 0.344 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.656 0.344 0.000
M47.82 Other spondylosis (Cervical region)
0.655 0.345 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.654 0.346 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.654 0.346 0.000
Y59 Other and unspecified vaccines and biological substances
0.653 0.346 0.000
Y58 Bacterial vaccines
0.653 0.346 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.653 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.653 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.653 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.653 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.653 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.653 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.653 0.346 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.653 0.346 0.000
O81 Single delivery by forceps and vacuum extractor
0.653 0.346 0.000
H71 Cholesteatoma of middle ear
0.653 0.347 0.000
H72.2 Other marginal perforations of tympanic membrane
0.653 0.347 0.000
H72.1 Attic perforation of tympanic membrane
0.653 0.347 0.000
A07 Other protozoal intestinal diseases
0.653 0.347 0.000
A06 Amoebiasis
0.653 0.347 0.000
A05 Other bacterial foodborne intoxications
0.653 0.347 0.000
A03 Shigellosis
0.653 0.347 0.000
A01 Typhoid and paratyphoid fevers
0.653 0.347 0.000
A00 Cholera
0.653 0.347 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.651 0.349 0.000
T51.9 Alcohol, unspecified
0.651 0.349 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.648 0.352 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.648 0.352 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.648 0.352 0.000
S32 Fracture of lumbar spine and pelvis
0.648 0.352 0.000
N28.0 Ischaemia and infarction of kidney
0.647 0.353 0.000
T63 Toxic effect of contact with venomous animals
0.646 0.354 0.000
N28.8 Other specified disorders of kidney and ureter
0.646 0.354 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.645 0.355 0.000
I62 Other nontraumatic intracranial haemorrhage
0.645 0.355 0.000
O66 Other obstructed labour
0.645 0.355 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.645 0.355 0.000
Q35-Q37 Cleft lip and cleft palate
0.645 0.355 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.355 0.000
B91 Sequelae of poliomyelitis
0.644 0.356 0.000
B59 Pneumocystosis
0.643 0.357 0.000
M20-M25 Other joint disorders
0.643 0.357 0.000
A02 Other Salmonella infections
0.641 0.359 0.000
A48 Other bacterial diseases, not elsewhere classified
0.640 0.360 0.000
A44 Bartonellosis
0.640 0.360 0.000
A43 Nocardiosis
0.640 0.360 0.000
A42 Actinomycosis
0.640 0.360 0.000
A39 Meningococcal infection
0.640 0.360 0.000
A37 Whooping cough
0.640 0.360 0.000
A36 Diphtheria
0.640 0.360 0.000
A32 Listeriosis
0.640 0.360 0.000
A31 Infection due to other mycobacteria
0.640 0.360 0.000
A30 Leprosy [Hansen's disease]
0.640 0.360 0.000
A38 Scarlet fever
0.640 0.360 0.000
A35 Other tetanus
0.640 0.360 0.000
A34 Obstetrical tetanus
0.640 0.360 0.000
A33 Tetanus neonatorum
0.640 0.360 0.000
B25 Cytomegaloviral disease
0.640 0.360 0.000
N05.1 Focal and segmental glomerular lesions
0.639 0.361 0.000
I45.2 Bifascicular block
0.638 0.361 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.638 0.362 0.000
S99 Other and unspecified injuries of ankle and foot
0.638 0.362 0.000
I67.9 Cerebrovascular disease, unspecified
0.637 0.363 0.000
O80.0 Spontaneous vertex delivery
0.637 0.363 0.000
T42.4 Benzodiazepines
0.637 0.363 0.000
H60 Otitis externa
0.636 0.364 0.000
H69.0 Patulous Eustachian tube
0.636 0.364 0.000
N05.2 Diffuse membranous glomerulonephritis
0.636 0.364 0.000
O85-O92 Complications predominantly related to the puerperium
0.636 0.364 0.000
S56 Injury of muscle and tendon at forearm level
0.636 0.364 0.000
B16 Acute hepatitis B
0.635 0.364 0.000
F79 Unspecified mental retardation
0.635 0.364 0.000
F06.7 Mild cognitive disorder
0.635 0.365 0.000
I45.3 Trifascicular block
0.635 0.365 0.000
M47.9 Spondylosis, unspecified
0.635 0.365 0.000
N19 Unspecified renal failure
0.634 0.366 0.000
N71 Inflammatory disease of uterus, except cervix
0.634 0.366 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.632 0.367 0.000
T51.8 Other alcohols
0.632 0.368 0.000
T51.3 Fusel oil
0.632 0.368 0.000
T51.2 2-Propanol
0.632 0.368 0.000
T51.1 Methanol
0.632 0.368 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.630 0.370 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.630 0.370 0.000
T39.4 Antirheumatics, not elsewhere classified
0.630 0.370 0.000
T39.2 Pyrazolone derivatives
0.630 0.370 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.630 0.370 0.000
A04.9 Bacterial intestinal infection, unspecified
0.629 0.370 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.629 0.370 0.000
A04.4 Other intestinal Escherichia coli infections
0.629 0.370 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.629 0.370 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.629 0.370 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.629 0.370 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.629 0.370 0.000
B80 Enterobiasis
0.629 0.371 0.000
S52 Fracture of forearm
0.629 0.371 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.629 0.371 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.628 0.371 0.000
N03.8 Other
0.627 0.372 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.627 0.372 0.000
N03.6 Dense deposit disease
0.627 0.372 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.627 0.372 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.627 0.372 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.627 0.372 0.000
N03.2 Diffuse membranous glomerulonephritis
0.627 0.372 0.000
N03.1 Focal and segmental glomerular lesions
0.627 0.372 0.000
N03.0 Minor glomerular abnormality
0.627 0.372 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.627 0.372 0.000
B33 Other viral diseases, not elsewhere classified
0.627 0.373 0.000
B30 Viral conjunctivitis
0.627 0.373 0.000
B27 Infectious mononucleosis
0.627 0.373 0.000
B26 Mumps
0.627 0.373 0.000
I77.1 Stricture of artery
0.627 0.373 0.000
O61 Failed induction of labour
0.627 0.373 0.000
H74 Other disorders of middle ear and mastoid
0.626 0.374 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.625 0.374 0.000
F00 Dementia in Alzheimer's disease
0.625 0.375 0.000
N61 Inflammatory disorders of breast
0.625 0.375 0.000
M05 Seropositive rheumatoid arthritis
0.624 0.375 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.624 0.376 0.000
S51 Open wound of forearm
0.623 0.377 0.000
M46 Other inflammatory spondylopathies
0.623 0.377 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.622 0.378 0.000
B15 Acute hepatitis A
0.621 0.379 0.000
V48 Car occupant injured in noncollision transport accident
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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