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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75095063
log Bayes Factor = 21.3072
Chromosome 11   position 35,550,982  (GRCh37) Explore rs75095063 on Ensembl!
Variant rs75095063 is part of Cluster X0167

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.999 0.001 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.999 0.001 0.000
Z96 Presence of other functional implants
0.997 0.003 0.000
Z96.6 Presence of orthopaedic joint implants
0.996 0.004 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
Z80 Family history of malignant neoplasm
0.986 0.014 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
Z03.8 Observation for other suspected diseases and conditions
0.977 0.023 0.000
Chapter VIII Diseases of the ear and mastoid process
0.970 0.030 0.000
M81 Osteoporosis without pathological fracture
0.969 0.031 0.000
Z85 Personal history of malignant neoplasm
0.968 0.032 0.000
C44.1 Skin of eyelid, including canthus
0.967 0.033 0.000
M47 Spondylosis
0.965 0.035 0.000
Z93 Artificial opening status
0.964 0.036 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.960 0.040 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.960 0.040 0.000
S20-S29 Injuries to the thorax
0.959 0.041 0.000
M23 Internal derangement of knee
0.958 0.042 0.000
C44.7 Skin of lower limb, including hip
0.958 0.042 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.954 0.046 0.000
M81.9 Osteoporosis, unspecified
0.953 0.047 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.948 0.052 0.000
H90-H95 Other disorders of ear
0.948 0.052 0.000
S70-S79 Injuries to the hip and thigh
0.946 0.054 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.946 0.054 0.000
Z03.1 Observation for suspected malignant neoplasm
0.942 0.058 0.000
C43 Malignant melanoma of skin
0.940 0.060 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.934 0.066 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.929 0.071 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.923 0.077 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.923 0.077 0.000
Z45 Adjustment and management of implanted device
0.922 0.078 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.921 0.079 0.000
Z90.1 Acquired absence of breast(s)
0.919 0.081 0.000
C44.6 Skin of upper limb, including shoulder
0.919 0.081 0.000
Z98 Other postsurgical states
0.918 0.082 0.000
Z86 Personal history of certain other diseases
0.918 0.082 0.000
M25 Other joint disorders, not elsewhere classified
0.913 0.087 0.000
T81 Complications of procedures, not elsewhere classified
0.911 0.089 0.000
D00-D09 In situ neoplasms
0.908 0.092 0.000
Z12 Special screening examination for neoplasms
0.907 0.093 0.000
M47.9 Spondylosis, unspecified
0.902 0.098 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.902 0.098 0.000
M21 Other acquired deformities of limbs
0.901 0.099 0.000
M81.98 Osteoporosis, unspecified (Other)
0.899 0.101 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.898 0.102 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.896 0.104 0.000
M70-M79 Other soft tissue disorders
0.894 0.106 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.893 0.107 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.891 0.109 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.888 0.112 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.888 0.112 0.000
M15-M19 Arthrosis
0.885 0.115 0.000
E70-E90 Metabolic disorders
0.885 0.115 0.000
M47.8 Other spondylosis
0.883 0.117 0.000
H91 Other hearing loss
0.881 0.119 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.881 0.119 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
M40-M43 Deforming dorsopathies
0.879 0.121 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.878 0.122 0.000
C15-C26 Malignant neoplasms of digestive organs
0.878 0.122 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.876 0.124 0.000
C34 Malignant neoplasm of bronchus and lung
0.876 0.124 0.000
Z90.2 Acquired absence of lung [part of]
0.872 0.128 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.870 0.130 0.000
E00-E07 Disorders of thyroid gland
0.867 0.133 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.866 0.134 0.000
Z04 Examination and observation for other reasons
0.861 0.139 0.000
M17 Gonarthrosis [arthrosis of knee]
0.861 0.139 0.000
Z90.0 Acquired absence of part of head and neck
0.860 0.140 0.000
C44.3 Skin of other and unspecified parts of face
0.860 0.140 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.858 0.142 0.000
E78.5 Hyperlipidaemia, unspecified
0.857 0.143 0.000
C44.2 Skin of ear and external auricular canal
0.856 0.143 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.856 0.144 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.854 0.146 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.854 0.146 0.000
H92 Otalgia and effusion of ear
0.851 0.149 0.000
Y42.5 Other oestrogens and progestogens
0.851 0.149 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.846 0.154 0.000
S72 Fracture of femur
0.846 0.154 0.000
Y83.6 Removal of other organ (partial) (total)
0.846 0.154 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.845 0.155 0.000
Z13 Special screening examination for other diseases and disorders
0.845 0.155 0.000
V10-V19 Pedal cyclist injured in transport accident
0.844 0.156 0.000
Z40 Prophylactic surgery
0.844 0.156 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.844 0.156 0.000
Y43 Primarily systemic agents
0.844 0.156 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.843 0.157 0.000
C64-C68 Malignant neoplasms of urinary tract
0.839 0.161 0.000
M17.1 Other primary gonarthrosis
0.839 0.161 0.000
Z93.1 Gastrostomy status
0.838 0.162 0.000
M23.3 Other meniscus derangements
0.837 0.163 0.000
C44.5 Skin of trunk
0.837 0.163 0.000
T86 Failure and rejection of transplanted organs and tissues
0.835 0.165 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.835 0.165 0.000
E50-E64 Other nutritional deficiencies
0.834 0.166 0.000
H91.9 Hearing loss, unspecified
0.833 0.167 0.000
Y52 Agents primarily affecting the cardiovascular system
0.828 0.172 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.825 0.175 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.823 0.177 0.000
Z45.2 Adjustment and management of vascular access device
0.821 0.179 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.821 0.179 0.000
C43.5 Malignant melanoma of trunk
0.819 0.181 0.000
C51-C58 Malignant neoplasms of female genital organs
0.819 0.181 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.818 0.182 0.000
Y95 Nosocomial condition
0.817 0.183 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.816 0.184 0.000
H65-H75 Diseases of middle ear and mastoid
0.815 0.185 0.000
C25 Malignant neoplasm of pancreas
0.815 0.185 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.814 0.186 0.000
S27 Injury of other and unspecified intrathoracic organs
0.814 0.186 0.000
Z42 Follow-up care involving plastic surgery
0.813 0.187 0.000
M47.2 Other spondylosis with radiculopathy
0.813 0.187 0.000
S70 Superficial injury of hip and thigh
0.812 0.188 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.812 0.188 0.000
M23.4 Loose body in knee
0.809 0.191 0.000
M22 Disorders of patella
0.809 0.191 0.000
E04 Other non-toxic goitre
0.808 0.192 0.000
M47.86 Other spondylosis (Lumbar region)
0.808 0.192 0.000
Z96.8 Presence of other specified functional implants
0.808 0.192 0.000
S22.0 Fracture of thoracic vertebra
0.807 0.193 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.806 0.194 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.804 0.196 0.000
C34.1 Upper lobe, bronchus or lung
0.801 0.199 0.000
M24 Other specific joint derangements
0.800 0.200 0.000
M84 Disorders of continuity of bone
0.799 0.201 0.000
M25.7 Osteophyte
0.797 0.203 0.000
G20-G26 Extrapyramidal and movement disorders
0.797 0.203 0.000
Z93.3 Colostomy status
0.796 0.204 0.000
S10-S19 Injuries to the neck
0.795 0.205 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.795 0.205 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.795 0.205 0.000
Y83.4 Other reconstructive surgery
0.793 0.207 0.000
M86-M90 Other osteopathies
0.793 0.207 0.000
M79.6 Pain in limb
0.792 0.208 0.000
Z96.2 Presence of otological and audiological implants
0.791 0.209 0.000
S20 Superficial injury of thorax
0.790 0.210 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.789 0.211 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.787 0.213 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.787 0.213 0.000
Z90.5 Acquired absence of kidney
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
T87 Complications peculiar to reattachment and amputation
0.785 0.215 0.000
Z98.0 Intestinal bypass and anastomosis status
0.784 0.216 0.000
Z96.7 Presence of other bone and tendon implants
0.783 0.217 0.000
E78.0 Pure hypercholesterolaemia
0.783 0.217 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.782 0.218 0.000
Z80.3 Family history of malignant neoplasm of breast
0.782 0.218 0.000
M35 Other systemic involvement of connective tissue
0.780 0.219 0.000
Y86 Sequelae of other accidents
0.781 0.219 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.780 0.219 0.000
Z45.8 Adjustment and management of other implanted devices
0.779 0.221 0.000
Z86.0 Personal history of other neoplasms
0.778 0.222 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.777 0.223 0.000
Y83.5 Amputation of limb(s)
0.775 0.225 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.774 0.226 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.773 0.227 0.000
Z54 Convalescence
0.772 0.227 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.772 0.228 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.772 0.228 0.000
Y40 Systemic antibiotics
0.772 0.228 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.771 0.229 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.771 0.229 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.771 0.229 0.000
Z93.5 Cystostomy status
0.770 0.230 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
S72.0 Fracture of neck of femur
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.768 0.232 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.768 0.232 0.000
Z98.1 Arthrodesis status
0.767 0.233 0.000
M85 Other disorders of bone density and structure
0.766 0.234 0.000
C81 Hodgkin's disease
0.766 0.234 0.000
G82 Paraplegia and tetraplegia
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.763 0.237 0.000
D04 Carcinoma in situ of skin
0.762 0.238 0.000
M81.4 Drug-induced osteoporosis
0.762 0.238 0.000
Z93.2 Ileostomy status
0.761 0.239 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.760 0.240 0.000
Z95.0 Presence of cardiac pacemaker
0.760 0.240 0.000
G30-G32 Other degenerative diseases of the nervous system
0.759 0.241 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.758 0.242 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.758 0.242 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.757 0.243 0.000
M23.8 Other internal derangements of knee
0.755 0.245 0.000
T00-T07 Injuries involving multiple body regions
0.754 0.246 0.000
M25.5 Pain in joint
0.752 0.248 0.000
Y43.3 Other antineoplastic drugs
0.751 0.249 0.000
D09 Carcinoma in situ of other and unspecified sites
0.750 0.250 0.000
Y83.9 Surgical procedure, unspecified
0.749 0.251 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.749 0.251 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.748 0.252 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.748 0.252 0.000
E53 Deficiency of other B group vitamins
0.748 0.252 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.747 0.253 0.000
G90-G99 Other disorders of the nervous system
0.747 0.253 0.000
H93 Other disorders of ear, not elsewhere classified
0.747 0.253 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.746 0.254 0.000
Z03.3 Observation for suspected nervous system disorder
0.746 0.254 0.000
M21.3 Wrist or foot drop (acquired)
0.745 0.254 0.000
M91-M94 Chondropathies
0.745 0.255 0.000
H92.0 Otalgia
0.744 0.256 0.000
Z93.0 Tracheostomy status
0.742 0.258 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.741 0.259 0.000
S79 Other and unspecified injuries of hip and thigh
0.741 0.259 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.741 0.259 0.000
Z93.6 Other artificial openings of urinary tract status
0.740 0.260 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
T85.2 Mechanical complication of intraocular lens
0.739 0.261 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.739 0.261 0.000
G25 Other extrapyramidal and movement disorders
0.738 0.262 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.736 0.264 0.000
M43 Other deforming dorsopathies
0.736 0.264 0.000
E04.9 Non-toxic goitre, unspecified
0.735 0.265 0.000
D06 Carcinoma in situ of cervix uteri
0.734 0.266 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.734 0.266 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.734 0.266 0.000
E78.8 Other disorders of lipoprotein metabolism
0.734 0.266 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.734 0.266 0.000
M79.8 Other specified soft tissue disorders
0.734 0.266 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.733 0.267 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.732 0.268 0.000
C43.9 Malignant melanoma of skin, unspecified
0.732 0.268 0.000
C34.9 Bronchus or lung, unspecified
0.730 0.270 0.000
Z43 Attention to artificial openings
0.730 0.270 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.729 0.271 0.000
C45 Mesothelioma
0.728 0.272 0.000
M48 Other spondylopathies
0.728 0.272 0.000
M41 Scoliosis
0.728 0.272 0.000
C67 Malignant neoplasm of bladder
0.728 0.272 0.000
Chapter I Certain infectious and parasitic diseases
0.727 0.273 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.726 0.274 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.726 0.274 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
Chapter X Diseases of the respiratory system
0.726 0.274 0.000
M25.3 Other instability of joint
0.725 0.274 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.725 0.275 0.000
C25.0 Head of pancreas
0.725 0.275 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.723 0.277 0.000
G70-G73 Diseases of myoneural junction and muscle
0.723 0.277 0.000
T91 Sequelae of injuries of neck and trunk
0.723 0.277 0.000
Z98.8 Other specified postsurgical states
0.723 0.277 0.000
M35.3 Polymyalgia rheumatica
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
M17.9 Gonarthrosis, unspecified
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.720 0.280 0.000
C32 Malignant neoplasm of larynx
0.719 0.281 0.000
M34 Systemic sclerosis
0.718 0.282 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.282 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z10 Routine general health check-up of defined subpopulation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.717 0.283 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.717 0.283 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.716 0.284 0.000
C44.8 Overlapping lesion of skin
0.716 0.284 0.000
C20 Malignant neoplasm of rectum
0.716 0.284 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.716 0.284 0.000
Z03.0 Observation for suspected tuberculosis
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
Z96.9 Presence of functional implant, unspecified
0.715 0.285 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.715 0.285 0.000
Z96.4 Presence of endocrine implants
0.715 0.285 0.000
Z96.3 Presence of artificial larynx
0.715 0.285 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.715 0.285 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.714 0.286 0.000
Z04.3 Examination and observation following other accident
0.714 0.286 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.713 0.287 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
M21.2 Flexion deformity
0.712 0.288 0.000
H74 Other disorders of middle ear and mastoid
0.712 0.288 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.712 0.288 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.712 0.288 0.000
S72.00 Fracture of neck of femur (closed)
0.712 0.288 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.711 0.289 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.710 0.289 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.710 0.290 0.000
H90 Conductive and sensorineural hearing loss
0.709 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
Y83.3 Surgical operation with formation of external stoma
0.707 0.293 0.000
M83 Adult osteomalacia
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.293 0.000
Z89 Acquired absence of limb
0.707 0.293 0.000
M21.1 Varus deformity, not elsewhere classified
0.707 0.293 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.707 0.293 0.000
Z80.6 Family history of leukaemia
0.707 0.293 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.707 0.293 0.000
Z99.3 Dependence on wheelchair
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.706 0.294 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.705 0.295 0.000
C43.4 Malignant melanoma of scalp and neck
0.705 0.295 0.000
M25.51 Pain in joint (Shoulder region)
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.296 0.000
Z04.8 Examination and observation for other specified reasons
0.704 0.296 0.000
S60-S69 Injuries to the wrist and hand
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
T90 Sequelae of injuries of head
0.702 0.298 0.000
M23.49 Loose body in knee-Unspec lig/men
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.702 0.298 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.701 0.298 0.000
M46 Other inflammatory spondylopathies
0.700 0.300 0.000
Z41 Procedures for purposes other than remedying health state
0.699 0.301 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.699 0.301 0.000
C25.9 Pancreas, unspecified
0.698 0.302 0.000
S40-S49 Injuries to the shoulder and upper arm
0.697 0.303 0.000
M47.1 Other spondylosis with myelopathy
0.697 0.303 0.000
H92.1 Otorrhoea
0.696 0.303 0.000
E07 Other disorders of thyroid
0.696 0.304 0.000
M81.8 Other osteoporosis
0.695 0.305 0.000
M81.6 Localised osteoporosis [Lequesne]
0.695 0.305 0.000
M81.5 Idiopathic osteoporosis
0.695 0.305 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.695 0.305 0.000
M81.2 Osteoporosis of disuse
0.695 0.305 0.000
M81.1 Postoophorectomy osteoporosis
0.695 0.305 0.000
M81.0 Postmenopausal osteoporosis
0.695 0.305 0.000
M22.2 Patellofemoral disorders
0.695 0.305 0.000
M23.5 Chronic instability of knee
0.694 0.306 0.000
T92 Sequelae of injuries of upper limb
0.694 0.306 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.694 0.306 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.694 0.306 0.000
W20-W49 Exposure to inanimate mechanical forces
0.693 0.307 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.692 0.308 0.000
C66 Malignant neoplasm of ureter
0.691 0.309 0.000
Z93.9 Artificial opening status, unspecified
0.691 0.309 0.000
Z93.8 Other artificial opening status
0.691 0.309 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.690 0.310 0.000
G82.2 Paraplegia, unspecified
0.690 0.310 0.000
M80 Osteoporosis with pathological fracture
0.690 0.310 0.000
Z90.8 Acquired absence of other organs
0.690 0.310 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.689 0.311 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
M76 Enthesopathies of lower limb, excluding foot
0.687 0.312 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.687 0.313 0.000
S26 Injury of heart
0.687 0.313 0.000
S25 Injury of blood vessels of thorax
0.687 0.313 0.000
S24 Injury of nerves and spinal cord at thorax level
0.687 0.313 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.687 0.313 0.000
S21 Open wound of thorax
0.687 0.313 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.687 0.313 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.687 0.313 0.000
M23.9 Internal derangement of knee, unspecified
0.687 0.313 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.687 0.313 0.000
M23.1 Discoid meniscus (congenital)
0.687 0.313 0.000
M23.0 Cystic meniscus
0.687 0.313 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.687 0.313 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.686 0.314 0.000
C53 Malignant neoplasm of cervix uteri
0.686 0.314 0.000
E53.8 Deficiency of other specified B group vitamins
0.686 0.314 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.684 0.316 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.684 0.316 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.683 0.316 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.683 0.316 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.683 0.316 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.683 0.316 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.683 0.316 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.683 0.316 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.683 0.316 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M77 Other enthesopathies
0.683 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.681 0.318 0.000
Z13.5 Special screening examination for eye and ear disorders
0.681 0.319 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.680 0.320 0.000
M25.8 Other specified joint disorders
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.680 0.320 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.680 0.320 0.000
E20-E35 Disorders of other endocrine glands
0.680 0.320 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.679 0.321 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
S78 Traumatic amputation of hip and thigh
0.678 0.322 0.000
S77 Crushing injury of hip and thigh
0.678 0.322 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.678 0.322 0.000
S75 Injury of blood vessels at hip and thigh level
0.678 0.322 0.000
S74 Injury of nerves at hip and thigh level
0.678 0.322 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.678 0.322 0.000
S71 Open wound of hip and thigh
0.678 0.322 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.678 0.322 0.000
Z52 Donors of organs and tissues
0.678 0.322 0.000
Z44 Fitting and adjustment of external prosthetic device
0.678 0.322 0.000
S27.0 Traumatic pneumothorax
0.678 0.322 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.676 0.324 0.000
T98 Sequelae of other and unspecified effects of external causes
0.674 0.325 0.000
S22.1 Multiple fractures of thoracic spine
0.674 0.326 0.000
E73 Lactose intolerance
0.674 0.326 0.000
C43.8 Overlapping malignant melanoma of skin
0.674 0.326 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.674 0.326 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.674 0.326 0.000
C43.0 Malignant melanoma of lip
0.674 0.326 0.000
T86.1 Kidney transplant failure and rejection
0.672 0.328 0.000
T86.0 Bone-marrow transplant rejection
0.672 0.328 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.671 0.329 0.000
M72 Fibroblastic disorders
0.671 0.329 0.000
E04.1 Non-toxic single thyroid nodule
0.670 0.330 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.670 0.330 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.670 0.330 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.670 0.330 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.670 0.330 0.000
C31 Malignant neoplasm of accessory sinuses
0.670 0.330 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.670 0.330 0.000
C37 Malignant neoplasm of thymus
0.670 0.330 0.000
C33 Malignant neoplasm of trachea
0.670 0.330 0.000
S20.2 Contusion of thorax
0.669 0.331 0.000
S29 Other and unspecified injuries of thorax
0.668 0.332 0.000
M79.0 Rheumatism, unspecified
0.667 0.333 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.667 0.333 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.666 0.333 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.666 0.333 0.000
Z88.2 Personal history of allergy to sulphonamides
0.666 0.334 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.664 0.335 0.000
V18.0 Driver injured in nontraffic accident
0.664 0.336 0.000
Y42.7 Androgens and anabolic congeners
0.663 0.337 0.000
Y42.9 Other and unspecified hormone antagonists
0.662 0.338 0.000
Y42.4 Oral contraceptives
0.662 0.338 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.662 0.338 0.000
Y42.2 Antithyroid drugs
0.662 0.338 0.000
Y42.1 Thyroid hormones and substitutes
0.662 0.338 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.662 0.338 0.000
C34.3 Lower lobe, bronchus or lung
0.662 0.338 0.000
M90 Osteopathies in diseases classified elsewhere
0.662 0.338 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.661 0.339 0.000
Z45.3 Adjustment and management of implanted hearing device
0.661 0.339 0.000
Z45.1 Adjustment and management of infusion pump
0.661 0.339 0.000
A30-A49 Other bacterial diseases
0.661 0.339 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.659 0.340 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.659 0.341 0.000
Z94 Transplanted organ and tissue status
0.659 0.341 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.658 0.342 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.658 0.342 0.000
M45 Ankylosing spondylitis
0.657 0.343 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.657 0.343 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.656 0.344 0.000
E04.0 Non-toxic diffuse goitre
0.656 0.344 0.000
Z04.5 Examination and observation following other inflicted injury
0.655 0.345 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.655 0.345 0.000
S80-S89 Injuries to the knee and lower leg
0.655 0.345 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.654 0.345 0.000
M25.2 Flail joint
0.654 0.346 0.000
M25.1 Fistula of joint
0.654 0.346 0.000
M25.0 Haemarthrosis
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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