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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75193007
log Bayes Factor = 15.0928
Chromosome 13   position 109,470,040  (GRCh37) Explore rs75193007 on Ensembl!
Variant rs75193007 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
Z30 Contraceptive management
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.983 0.017 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.968 0.032 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.968 0.032 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.966 0.034 0.000
C15-C26 Malignant neoplasms of digestive organs
0.963 0.037 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
M20-M25 Other joint disorders
0.957 0.043 0.000
M06 Other rheumatoid arthritis
0.954 0.046 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.948 0.052 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.947 0.053 0.000
O72 Postpartum haemorrhage
0.947 0.053 0.000
M50-M54 Other dorsopathies
0.946 0.054 0.000
G90-G99 Other disorders of the nervous system
0.945 0.055 0.000
M47 Spondylosis
0.941 0.059 0.000
C51-C58 Malignant neoplasms of female genital organs
0.940 0.060 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.935 0.065 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.932 0.068 0.000
M06.9 Rheumatoid arthritis, unspecified
0.925 0.075 0.000
Chapter IX Diseases of the circulatory system
0.925 0.075 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.925 0.075 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.919 0.081 0.000
Z34 Supervision of normal pregnancy
0.918 0.082 0.000
M48 Other spondylopathies
0.912 0.088 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.908 0.092 0.000
M47.9 Spondylosis, unspecified
0.905 0.095 0.000
M54 Dorsalgia
0.904 0.096 0.000
S00-S09 Injuries to the head
0.903 0.097 0.000
Chapter XXII Codes for special purposes
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.898 0.102 0.000
D00-D09 In situ neoplasms
0.898 0.102 0.000
M24 Other specific joint derangements
0.897 0.103 0.000
I60-I69 Cerebrovascular diseases
0.897 0.103 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
C56 Malignant neoplasm of ovary
0.895 0.105 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.893 0.107 0.000
Z36 Antenatal screening
0.892 0.108 0.000
B35-B49 Mycoses
0.891 0.109 0.000
O72.1 Other immediate postpartum haemorrhage
0.890 0.110 0.000
M15-M19 Arthrosis
0.886 0.114 0.000
C92 Myeloid leukaemia
0.880 0.120 0.000
C85.1 B-cell lymphoma, unspecified
0.879 0.121 0.000
M19 Other arthrosis
0.878 0.122 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.877 0.123 0.000
E50-E64 Other nutritional deficiencies
0.875 0.125 0.000
Z03.8 Observation for other suspected diseases and conditions
0.869 0.131 0.000
M19.9 Arthrosis, unspecified
0.868 0.132 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.868 0.132 0.000
B95-B98 Bacterial, viral and other infectious agents
0.867 0.133 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.866 0.134 0.000
C64-C68 Malignant neoplasms of urinary tract
0.859 0.141 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.858 0.142 0.000
M48.0 Spinal stenosis
0.857 0.143 0.000
E53 Deficiency of other B group vitamins
0.856 0.144 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.852 0.148 0.000
L20-L30 Dermatitis and eczema
0.851 0.149 0.000
G93 Other disorders of brain
0.848 0.152 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.844 0.156 0.000
M86-M90 Other osteopathies
0.843 0.157 0.000
E53.8 Deficiency of other specified B group vitamins
0.843 0.157 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.842 0.158 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.842 0.158 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.842 0.158 0.000
S20-S29 Injuries to the thorax
0.841 0.159 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.839 0.161 0.000
M06.0 Seronegative rheumatoid arthritis
0.837 0.163 0.000
C16 Malignant neoplasm of stomach
0.836 0.164 0.000
Z34.8 Supervision of other normal pregnancy
0.835 0.165 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.834 0.166 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.833 0.166 0.000
G70-G73 Diseases of myoneural junction and muscle
0.833 0.167 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.833 0.167 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.833 0.167 0.000
B15-B19 Viral hepatitis
0.832 0.168 0.000
B37 Candidiasis
0.832 0.168 0.000
T79-T79 Certain early complications of trauma
0.831 0.169 0.000
S60-S69 Injuries to the wrist and hand
0.830 0.170 0.000
L50-L54 Urticaria and erythema
0.829 0.171 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.827 0.173 0.000
Z39 Postpartum care and examination
0.825 0.175 0.000
L81 Other disorders of pigmentation
0.825 0.175 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.823 0.177 0.000
Z35 Supervision of high-risk pregnancy
0.820 0.180 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.819 0.181 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.818 0.182 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.816 0.184 0.000
C25 Malignant neoplasm of pancreas
0.816 0.184 0.000
O72.0 Third-stage haemorrhage
0.812 0.188 0.000
Chapter V Mental and behavioural disorders
0.812 0.188 0.000
S02 Fracture of skull and facial bones
0.810 0.190 0.000
M19.94 Arthrosis, unspecified (Hand)
0.810 0.190 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.810 0.190 0.000
M80-M85 Disorders of bone density and structure
0.806 0.194 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.805 0.195 0.000
M46 Other inflammatory spondylopathies
0.804 0.196 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.804 0.196 0.000
C20 Malignant neoplasm of rectum
0.804 0.196 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.801 0.199 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.801 0.199 0.000
C81 Hodgkin's disease
0.800 0.200 0.000
M22 Disorders of patella
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
S01 Open wound of head
0.796 0.204 0.000
G62 Other polyneuropathies
0.795 0.205 0.000
M54.3 Sciatica
0.794 0.206 0.000
C83.3 Large cell (diffuse)
0.794 0.206 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.794 0.206 0.000
Y43 Primarily systemic agents
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
T87 Complications peculiar to reattachment and amputation
0.793 0.207 0.000
O36 Maternal care for other known or suspected foetal problems
0.792 0.208 0.000
G20-G26 Extrapyramidal and movement disorders
0.790 0.210 0.000
M54.6 Pain in thoracic spine
0.789 0.211 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.788 0.212 0.000
M25 Other joint disorders, not elsewhere classified
0.788 0.212 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.788 0.212 0.000
M48.02 Spinal stenosis (Cervical region)
0.786 0.214 0.000
I95 Hypotension
0.786 0.214 0.000
L40-L45 Papulosquamous disorders
0.785 0.215 0.000
M20 Acquired deformities of fingers and toes
0.784 0.216 0.000
G95 Other diseases of spinal cord
0.783 0.217 0.000
O66 Other obstructed labour
0.783 0.217 0.000
L80 Vitiligo
0.781 0.219 0.000
O85-O92 Complications predominantly related to the puerperium
0.781 0.219 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.780 0.220 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.779 0.221 0.000
M06.4 Inflammatory polyarthropathy
0.779 0.221 0.000
E20-E35 Disorders of other endocrine glands
0.777 0.223 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.776 0.224 0.000
M51 Other intervertebral disk disorders
0.775 0.225 0.000
Y48 Anaesthetics and therapeutic gases
0.773 0.227 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.772 0.228 0.000
O71 Other obstetric trauma
0.772 0.228 0.000
B37.0 Candidal stomatitis
0.771 0.229 0.000
M54.5 Low back pain
0.770 0.230 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.769 0.231 0.000
O62 Abnormalities of forces of labour
0.768 0.232 0.000
M70-M79 Other soft tissue disorders
0.768 0.232 0.000
C67 Malignant neoplasm of bladder
0.768 0.232 0.000
I61 Intracerebral haemorrhage
0.768 0.232 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.768 0.232 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.767 0.233 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.766 0.234 0.000
O48 Prolonged pregnancy
0.766 0.234 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.766 0.234 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.765 0.234 0.000
G93.3 Postviral fatigue syndrome
0.765 0.235 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.765 0.235 0.000
L91 Hypertrophic disorders of skin
0.765 0.235 0.000
Y57 Other and unspecified drugs and medicaments
0.765 0.235 0.000
M24.5 Contracture of joint
0.762 0.238 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.761 0.239 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.761 0.239 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.760 0.240 0.000
G91 Hydrocephalus
0.760 0.240 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.759 0.241 0.000
S32 Fracture of lumbar spine and pelvis
0.756 0.244 0.000
Z31 Procreative management
0.756 0.244 0.000
S62 Fracture at wrist and hand level
0.756 0.244 0.000
L81.4 Other melanin hyperpigmentation
0.754 0.245 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.753 0.247 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.753 0.247 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.752 0.248 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.752 0.248 0.000
U80 Agent resistant to penicillin and related antibiotics
0.751 0.248 0.000
G30-G32 Other degenerative diseases of the nervous system
0.750 0.250 0.000
C92.0 Acute myeloid leukaemia
0.749 0.251 0.000
L98.0 Pyogenic granuloma
0.748 0.252 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.748 0.252 0.000
B99-B99 Other infectious diseases
0.747 0.253 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.744 0.256 0.000
G61 Inflammatory polyneuropathy
0.744 0.256 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.744 0.256 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.743 0.257 0.000
Z32 Pregnancy examination and test
0.742 0.258 0.000
M21 Other acquired deformities of limbs
0.740 0.260 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.740 0.260 0.000
S40-S49 Injuries to the shoulder and upper arm
0.739 0.261 0.000
M24.0 Loose body in joint
0.739 0.261 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.738 0.262 0.000
Z34.0 Supervision of normal first pregnancy
0.737 0.263 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.736 0.264 0.000
M54.4 Lumbago with sciatica
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
A00-A09 Intestinal infectious diseases
0.734 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
S01.8 Open wound of other parts of head
0.733 0.267 0.000
C16.9 Stomach, unspecified
0.732 0.268 0.000
M47.8 Other spondylosis
0.732 0.268 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.731 0.268 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.731 0.269 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.731 0.269 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
Z03.1 Observation for suspected malignant neoplasm
0.730 0.270 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.730 0.270 0.000
C26.0 Intestinal tract, part unspecified
0.730 0.270 0.000
M48.06 Spinal stenosis (Lumbar region)
0.730 0.270 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.729 0.271 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.728 0.272 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.727 0.273 0.000
C92.1 Chronic myeloid leukaemia
0.726 0.273 0.000
M14 Arthropathies in other diseases classified elsewhere
0.725 0.275 0.000
L85 Other epidermal thickening
0.724 0.276 0.000
I60 Subarachnoid haemorrhage
0.724 0.276 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.724 0.276 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
I62 Other nontraumatic intracranial haemorrhage
0.722 0.278 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.722 0.278 0.000
I67 Other cerebrovascular diseases
0.721 0.279 0.000
G90 Disorders of autonomic nervous system
0.721 0.279 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.720 0.280 0.000
O30 Multiple gestation
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.280 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.720 0.280 0.000
T86 Failure and rejection of transplanted organs and tissues
0.720 0.280 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.720 0.280 0.000
Z04 Examination and observation for other reasons
0.719 0.281 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.719 0.281 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.719 0.281 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.718 0.282 0.000
O63 Long labour
0.718 0.282 0.000
M35 Other systemic involvement of connective tissue
0.718 0.282 0.000
S05 Injury of eye and orbit
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z38 Liveborn infants according to place of birth
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z30.3 Menstrual extraction
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
B25-B34 Other viral diseases
0.715 0.285 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.715 0.285 0.000
Y52 Agents primarily affecting the cardiovascular system
0.715 0.285 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.715 0.285 0.000
C51 Malignant neoplasm of vulva
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.712 0.287 0.000
T90 Sequelae of injuries of head
0.712 0.288 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
C95 Leukaemia of unspecified cell type
0.712 0.288 0.000
C94 Other leukaemias of specified cell type
0.712 0.288 0.000
C93 Monocytic leukaemia
0.712 0.288 0.000
C88 Malignant immunoproliferative diseases
0.712 0.288 0.000
C86 Other specified types of T/NK-cell lymphoma
0.712 0.288 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.712 0.288 0.000
L29 Pruritus
0.711 0.289 0.000
W00-W19 Falls
0.711 0.289 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.710 0.290 0.000
D03 Melanoma in situ
0.710 0.290 0.000
Z30.9 Contraceptive management, unspecified
0.710 0.290 0.000
Z30.8 Other contraceptive management
0.710 0.290 0.000
Z30.4 Surveillance of contraceptive drugs
0.710 0.290 0.000
Z30.0 General counselling and advice on contraception
0.710 0.290 0.000
Z03.3 Observation for suspected nervous system disorder
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.709 0.291 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.709 0.291 0.000
L27 Dermatitis due to substances taken internally
0.708 0.291 0.000
C21 Malignant neoplasm of anus and anal canal
0.708 0.292 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
M47.1 Other spondylosis with myelopathy
0.707 0.292 0.000
Z37 Outcome of delivery
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.707 0.293 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.707 0.293 0.000
M05 Seropositive rheumatoid arthritis
0.706 0.294 0.000
Z10 Routine general health check-up of defined subpopulation
0.705 0.295 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.704 0.296 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.703 0.297 0.000
M90 Osteopathies in diseases classified elsewhere
0.703 0.297 0.000
L50 Urticaria
0.702 0.298 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.702 0.298 0.000
M91-M94 Chondropathies
0.702 0.298 0.000
B37.8 Candidiasis of other sites
0.701 0.298 0.000
G62.9 Polyneuropathy, unspecified
0.701 0.299 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.700 0.300 0.000
O47 False labour
0.700 0.300 0.000
O61 Failed induction of labour
0.700 0.300 0.000
O41 Other disorders of amniotic fluid and membranes
0.699 0.301 0.000
O43 Placental disorders
0.699 0.301 0.000
M22.2 Patellofemoral disorders
0.699 0.301 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.698 0.302 0.000
O24 Diabetes mellitus in pregnancy
0.697 0.303 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.697 0.303 0.000
O44 Placenta praevia
0.696 0.304 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.695 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.304 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
B50-B64 Protozoal diseases
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.694 0.306 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.694 0.306 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.694 0.306 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.694 0.306 0.000
Z03.0 Observation for suspected tuberculosis
0.694 0.306 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.694 0.306 0.000
S61 Open wound of wrist and hand
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.693 0.307 0.000
U51 Admission status on psychiatric patients
0.693 0.307 0.000
O21 Excessive vomiting in pregnancy
0.693 0.307 0.000
Chapter X Diseases of the respiratory system
0.693 0.307 0.000
M12 Other specific arthropathies
0.692 0.308 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.692 0.308 0.000
M08 Juvenile arthritis
0.692 0.308 0.000
O69.8 Labour and delivery complicated by other cord complications
0.692 0.308 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.692 0.308 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.691 0.309 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.690 0.309 0.000
C17 Malignant neoplasm of small intestine
0.690 0.309 0.000
C23 Malignant neoplasm of gallbladder
0.690 0.309 0.000
M19.0 Primary arthrosis of other joints
0.690 0.310 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.689 0.311 0.000
E10-E14 Diabetes mellitus
0.689 0.311 0.000
C25.0 Head of pancreas
0.688 0.312 0.000
T87.4 Infection of amputation stump
0.688 0.312 0.000
C53 Malignant neoplasm of cervix uteri
0.687 0.312 0.000
G24 Dystonia
0.687 0.312 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.687 0.313 0.000
I95.1 Orthostatic hypotension
0.687 0.313 0.000
I95.9 Hypotension, unspecified
0.687 0.313 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
W50-W64 Exposure to animate mechanical forces
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V80-V89 Other land transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
M19.1 Posttraumatic arthrosis of other joints
0.687 0.313 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.314 0.000
M33 Dermatopolymyositis
0.686 0.314 0.000
M32 Systemic lupus erythematosus
0.686 0.314 0.000
M30 Polyarteritis nodosa and related conditions
0.686 0.314 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.686 0.314 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.686 0.314 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.685 0.315 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.685 0.315 0.000
T43.2 Other and unspecified antidepressants
0.684 0.316 0.000
M06.8 Other specified rheumatoid arthritis
0.684 0.316 0.000
M06.3 Rheumatoid nodule
0.684 0.316 0.000
M06.2 Rheumatoid bursitis
0.684 0.316 0.000
M06.1 Adult-onset Still's disease
0.684 0.316 0.000
C16.5 Lesser curvature of stomach, unspecified
0.684 0.316 0.000
B18 Chronic viral hepatitis
0.684 0.316 0.000
M20.5 Other deformities of toe(s) (acquired)
0.683 0.317 0.000
G40-G47 Episodic and paroxysmal disorders
0.683 0.317 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.682 0.317 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.682 0.318 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.682 0.318 0.000
Y43.3 Other antineoplastic drugs
0.682 0.318 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.682 0.318 0.000
D05 Carcinoma in situ of breast
0.682 0.318 0.000
D09 Carcinoma in situ of other and unspecified sites
0.681 0.319 0.000
S27 Injury of other and unspecified intrathoracic organs
0.681 0.319 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.680 0.320 0.000
C85.0 Lymphosarcoma
0.680 0.320 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.680 0.320 0.000
L93 Lupus erythematosus
0.679 0.321 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.679 0.321 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.679 0.321 0.000
L94 Other localised connective tissue disorders
0.679 0.321 0.000
L87 Transepidermal elimination disorders
0.679 0.321 0.000
L88 Pyoderma gangrenosum
0.679 0.321 0.000
L86 Keratoderma in diseases classified elsewhere
0.679 0.321 0.000
L83 Acanthosis nigricans
0.679 0.321 0.000
O72.3 Postpartum coagulation defects
0.679 0.321 0.000
M53 Other dorsopathies, not elsewhere classified
0.678 0.322 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.678 0.322 0.000
S29 Other and unspecified injuries of thorax
0.678 0.322 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.678 0.322 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.678 0.322 0.000
G92 Toxic encephalopathy
0.678 0.322 0.000
Z36.8 Other antenatal screening
0.677 0.323 0.000
Z03.4 Observation for suspected myocardial infarction
0.677 0.323 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.677 0.323 0.000
Z33 Pregnant state, incidental
0.677 0.323 0.000
M40-M43 Deforming dorsopathies
0.676 0.324 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.675 0.324 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.675 0.325 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.674 0.326 0.000
C58 Malignant neoplasm of placenta
0.674 0.326 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.674 0.326 0.000
C52 Malignant neoplasm of vagina
0.674 0.326 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.674 0.326 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.673 0.327 0.000
L28 Lichen simplex chronicus and prurigo
0.672 0.328 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.672 0.328 0.000
J20-J22 Other acute lower respiratory infections
0.671 0.329 0.000
A80-A89 Viral infections of the central nervous system
0.671 0.329 0.000
M54.2 Cervicalgia
0.671 0.329 0.000
O70 Perineal laceration during delivery
0.671 0.329 0.000
D07.5 Prostate
0.670 0.329 0.000
M25.7 Osteophyte
0.670 0.330 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.669 0.331 0.000
M89 Other disorders of bone
0.669 0.331 0.000
Y59 Other and unspecified vaccines and biological substances
0.668 0.332 0.000
Y58 Bacterial vaccines
0.668 0.332 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.668 0.332 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.668 0.332 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.668 0.332 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.668 0.332 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.668 0.332 0.000
M54.37 Sciatica (Lumbosacral region)
0.668 0.332 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.668 0.332 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.667 0.333 0.000
G72 Other myopathies
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.667 0.333 0.000
M24.54 Contracture of joint (Hand)
0.666 0.334 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.665 0.335 0.000
C25.2 Tail of pancreas
0.665 0.335 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.665 0.335 0.000
I30-I52 Other forms of heart disease
0.664 0.336 0.000
I00-I02 Acute rheumatic fever
0.663 0.336 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.663 0.336 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.663 0.336 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.663 0.336 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.663 0.336 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.663 0.337 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.662 0.337 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.661 0.339 0.000
U80.1 Methicillin resistant agent
0.661 0.339 0.000
C01 Malignant neoplasm of base of tongue
0.661 0.339 0.000
L92.0 Granuloma annulare
0.661 0.339 0.000
E28 Ovarian dysfunction
0.661 0.339 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.660 0.340 0.000
O23 Infections of genito-urinary tract in pregnancy
0.660 0.340 0.000
G61.8 Other inflammatory polyneuropathies
0.660 0.340 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.660 0.340 0.000
I99 Other and unspecified disorders of circulatory system
0.660 0.340 0.000
O45 Premature separation of placenta [abruptio placentae]
0.659 0.341 0.000
O33 Maternal care for known or suspected disproportion
0.659 0.341 0.000
O31 Complications specific to multiple gestation
0.659 0.341 0.000
O40 Polyhydramnios
0.659 0.341 0.000
M54.57 Low back pain (Lumbosacral region)
0.659 0.341 0.000
M34 Systemic sclerosis
0.658 0.342 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.658 0.342 0.000
Y48.3 Local anaesthetics
0.658 0.342 0.000
S02.4 Fracture of malar and maxillary bones
0.658 0.342 0.000
O00-O08 Pregnancy with abortive outcome
0.657 0.343 0.000
G93.4 Encephalopathy, unspecified
0.657 0.343 0.000
Z39.0 Care and examination immediately after delivery
0.657 0.343 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.656 0.344 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.656 0.344 0.000
Y40 Systemic antibiotics
0.655 0.345 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.655 0.345 0.000
T98 Sequelae of other and unspecified effects of external causes
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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