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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75193761
log Bayes Factor = 11.2566
Chromosome 16   position 67,233,243  (GRCh37) Explore rs75193761 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
N80 Endometriosis
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.998 0.002 0.000
M75 Shoulder lesions
0.995 0.005 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.993 0.007 0.000
M80-M85 Disorders of bone density and structure
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
D25 Leiomyoma of uterus
0.988 0.012 0.000
N83.2 Other and unspecified ovarian cysts
0.987 0.013 0.000
M81 Osteoporosis without pathological fracture
0.978 0.022 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.978 0.022 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.977 0.023 0.000
N80.0 Endometriosis of uterus
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
N60-N64 Disorders of breast
0.971 0.029 0.000
G40-G47 Episodic and paroxysmal disorders
0.971 0.029 0.000
M65-M68 Disorders of synovium and tendon
0.967 0.033 0.000
M81.9 Osteoporosis, unspecified
0.966 0.034 0.000
N80.1 Endometriosis of ovary
0.960 0.040 0.000
G47 Sleep disorders
0.956 0.044 0.000
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.950 0.050 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.949 0.051 0.000
C15-C26 Malignant neoplasms of digestive organs
0.945 0.055 0.000
L60-L75 Disorders of skin appendages
0.942 0.058 0.000
D00-D09 In situ neoplasms
0.942 0.058 0.000
L82 Seborrhoeic keratosis
0.938 0.062 0.000
M79.7 Fibromyalgia
0.930 0.070 0.000
D25.2 Subserosal leiomyoma of uterus
0.928 0.072 0.000
N80.8 Other endometriosis
0.927 0.073 0.000
N62 Hypertrophy of breast
0.924 0.076 0.000
D25.9 Leiomyoma of uterus, unspecified
0.924 0.076 0.000
M65 Synovitis and tenosynovitis
0.924 0.076 0.000
D25.1 Intramural leiomyoma of uterus
0.916 0.084 0.000
M75.1 Rotator cuff syndrome
0.914 0.086 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.905 0.095 0.000
M75.4 Impingement syndrome of shoulder
0.899 0.101 0.000
G47.3 Sleep apnoea
0.897 0.103 0.000
M71 Other bursopathies
0.897 0.103 0.000
M79.79 Fibromyalgia (Site unspecified)
0.896 0.104 0.000
M84 Disorders of continuity of bone
0.896 0.104 0.000
N80.3 Endometriosis of pelvic peritoneum
0.889 0.110 0.000
D17 Benign lipomatous neoplasm
0.885 0.115 0.000
M75.0 Adhesive capsulitis of shoulder
0.882 0.118 0.000
Chapter IX Diseases of the circulatory system
0.880 0.120 0.000
E27 Other disorders of adrenal gland
0.879 0.121 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.879 0.121 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.876 0.124 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.876 0.124 0.000
Chapter VII Diseases of the eye and adnexa
0.871 0.129 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.867 0.133 0.000
D06 Carcinoma in situ of cervix uteri
0.866 0.134 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.866 0.134 0.000
M79.6 Pain in limb
0.865 0.135 0.000
I10-I15 Hypertensive diseases
0.864 0.136 0.000
Chapter V Mental and behavioural disorders
0.863 0.137 0.000
G70-G73 Diseases of myoneural junction and muscle
0.861 0.139 0.000
N84 Polyp of female genital tract
0.860 0.140 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.860 0.140 0.000
G44 Other headache syndromes
0.859 0.141 0.000
E65-E68 Obesity and other hyperalimentation
0.859 0.141 0.000
C20 Malignant neoplasm of rectum
0.858 0.142 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.854 0.146 0.000
I10 Essential (primary) hypertension
0.852 0.148 0.000
M75.3 Calcific tendinitis of shoulder
0.849 0.151 0.000
D11 Benign neoplasm of major salivary glands
0.847 0.153 0.000
Chapter I Certain infectious and parasitic diseases
0.845 0.155 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.843 0.157 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.841 0.159 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.839 0.161 0.000
N80.5 Endometriosis of intestine
0.837 0.163 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.837 0.163 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.829 0.171 0.000
N60 Benign mammary dysplasia
0.828 0.172 0.000
S90-S99 Injuries to the ankle and foot
0.828 0.172 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.826 0.174 0.000
D30 Benign neoplasm of urinary organs
0.823 0.177 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.823 0.177 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.823 0.177 0.000
N80.2 Endometriosis of Fallopian tube
0.822 0.178 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.820 0.180 0.000
N84.1 Polyp of cervix uteri
0.820 0.180 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.820 0.180 0.000
N97 Female infertility
0.818 0.182 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.818 0.182 0.000
F30-F39 Mood [affective] disorders
0.817 0.183 0.000
N00-N08 Glomerular diseases
0.817 0.183 0.000
N10-N16 Renal tubulo-interstitial diseases
0.817 0.183 0.000
D06.9 Cervix, unspecified
0.812 0.188 0.000
G47.9 Sleep disorder, unspecified
0.811 0.189 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.811 0.189 0.000
N17-N19 Renal failure
0.807 0.193 0.000
E21.0 Primary hyperparathyroidism
0.806 0.194 0.000
H40-H42 Glaucoma
0.806 0.194 0.000
D31 Benign neoplasm of eye and adnexa
0.806 0.194 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.805 0.195 0.000
M67 Other disorders of synovium and tendon
0.802 0.198 0.000
M40-M43 Deforming dorsopathies
0.801 0.199 0.000
L72.1 Trichilemmal cyst
0.800 0.200 0.000
L84 Corns and callosities
0.800 0.200 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.799 0.201 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.799 0.201 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.797 0.203 0.000
E00-E07 Disorders of thyroid gland
0.797 0.203 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.796 0.204 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.796 0.204 0.000
N20-N23 Urolithiasis
0.793 0.207 0.000
L72.0 Epidermal cyst
0.792 0.208 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.789 0.210 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.789 0.211 0.000
D24 Benign neoplasm of breast
0.788 0.212 0.000
D23 Other benign neoplasms of skin
0.784 0.216 0.000
S90 Superficial injury of ankle and foot
0.782 0.218 0.000
D10 Benign neoplasm of mouth and pharynx
0.782 0.218 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.781 0.219 0.000
D22 Melanocytic naevi
0.780 0.220 0.000
H02 Other disorders of eyelid
0.778 0.222 0.000
D32 Benign neoplasm of meninges
0.776 0.224 0.000
E27.9 Disorder of adrenal gland, unspecified
0.775 0.225 0.000
C25 Malignant neoplasm of pancreas
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.228 0.000
D04 Carcinoma in situ of skin
0.772 0.228 0.000
M75.9 Shoulder lesion, unspecified
0.771 0.229 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.771 0.229 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.770 0.230 0.000
I05-I09 Chronic rheumatic heart diseases
0.770 0.230 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.769 0.231 0.000
C64-C68 Malignant neoplasms of urinary tract
0.769 0.231 0.000
N82 Fistulae involving female genital tract
0.768 0.232 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.766 0.234 0.000
L73 Other follicular disorders
0.765 0.235 0.000
L80 Vitiligo
0.762 0.238 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.761 0.239 0.000
H40 Glaucoma
0.760 0.240 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.760 0.240 0.000
N64 Other disorders of breast
0.759 0.241 0.000
E66 Obesity
0.758 0.242 0.000
M79.69 Pain in limb (Site unspecified)
0.758 0.242 0.000
Q50-Q56 Congenital malformations of genital organs
0.757 0.243 0.000
M81.4 Drug-induced osteoporosis
0.757 0.243 0.000
H01 Other inflammation of eyelid
0.756 0.244 0.000
N61 Inflammatory disorders of breast
0.755 0.245 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.755 0.245 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.755 0.245 0.000
M79.5 Residual foreign body in soft tissue
0.752 0.248 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.752 0.248 0.000
M79.0 Rheumatism, unspecified
0.751 0.249 0.000
C77.2 Intra-abdominal lymph nodes
0.750 0.250 0.000
G44.0 Cluster headache syndrome
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
D36 Benign neoplasm of other and unspecified sites
0.749 0.250 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.749 0.251 0.000
Q60-Q64 Congenital malformations of the urinary system
0.749 0.251 0.000
M75.2 Bicipital tendinitis
0.748 0.252 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.747 0.253 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.745 0.255 0.000
L83 Acanthosis nigricans
0.745 0.255 0.000
M75.5 Bursitis of shoulder
0.745 0.255 0.000
Q00-Q07 Congenital malformations of the nervous system
0.744 0.256 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
D16 Benign neoplasm of bone and articular cartilage
0.742 0.258 0.000
C17 Malignant neoplasm of small intestine
0.742 0.258 0.000
D27 Benign neoplasm of ovary
0.741 0.259 0.000
C16 Malignant neoplasm of stomach
0.740 0.260 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.740 0.260 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.740 0.260 0.000
D11.0 Parotid gland
0.739 0.261 0.000
L85 Other epidermal thickening
0.739 0.261 0.000
H02.3 Blepharochalasis
0.738 0.262 0.000
C34 Malignant neoplasm of bronchus and lung
0.737 0.263 0.000
E22 Hyperfunction of pituitary gland
0.737 0.263 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
N23 Unspecified renal colic
0.734 0.266 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.734 0.266 0.000
F32 Depressive episode
0.733 0.267 0.000
N73 Other female pelvic inflammatory diseases
0.733 0.267 0.000
M60-M63 Disorders of muscles
0.732 0.268 0.000
M79.1 Myalgia
0.731 0.269 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.730 0.270 0.000
M81.98 Osteoporosis, unspecified (Other)
0.730 0.270 0.000
E23 Hypofunction and other disorders of pituitary gland
0.730 0.270 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.729 0.270 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
G51 Facial nerve disorders
0.729 0.271 0.000
M79.62 Pain in limb (Upper arm)
0.729 0.271 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.728 0.272 0.000
D29 Benign neoplasm of male genital organs
0.728 0.272 0.000
C01 Malignant neoplasm of base of tongue
0.727 0.273 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.726 0.274 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.726 0.274 0.000
F31 Bipolar affective disorder
0.725 0.274 0.000
E27.8 Other specified disorders of adrenal gland
0.725 0.275 0.000
M85 Other disorders of bone density and structure
0.724 0.275 0.000
M72 Fibroblastic disorders
0.721 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.721 0.279 0.000
N99-N99 Other disorders of the genitourinary system
0.721 0.279 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.720 0.280 0.000
G30-G32 Other degenerative diseases of the nervous system
0.719 0.281 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.719 0.281 0.000
M79.63 Pain in limb (Forearm)
0.718 0.282 0.000
E03 Other hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
N18 Chronic renal failure
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
N80.6 Endometriosis in cutaneous scar
0.716 0.283 0.000
H40.9 Glaucoma, unspecified
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.716 0.284 0.000
N91 Absent, scanty and rare menstruation
0.716 0.284 0.000
N96 Habitual aborter
0.716 0.284 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.716 0.284 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.715 0.285 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.714 0.286 0.000
M75.8 Other shoulder lesions
0.713 0.287 0.000
C15 Malignant neoplasm of oesophagus
0.712 0.288 0.000
I11 Hypertensive heart disease
0.712 0.288 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.712 0.288 0.000
N83.7 Haematoma of broad ligament
0.712 0.288 0.000
N83.6 Haematosalpinx
0.712 0.288 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.712 0.288 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.712 0.288 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.712 0.288 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
M83 Adult osteomalacia
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
M66 Spontaneous rupture of synovium and tendon
0.710 0.290 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.709 0.290 0.000
N71 Inflammatory disease of uterus, except cervix
0.708 0.292 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.707 0.293 0.000
E66.8 Other obesity
0.707 0.293 0.000
D03 Melanoma in situ
0.704 0.296 0.000
C18 Malignant neoplasm of colon
0.704 0.296 0.000
D23.2 Skin of ear and external auricular canal
0.703 0.297 0.000
H01.0 Blepharitis
0.703 0.297 0.000
M65.8 Other synovitis and tenosynovitis
0.702 0.298 0.000
M81.8 Other osteoporosis
0.701 0.299 0.000
M81.6 Localised osteoporosis [Lequesne]
0.701 0.299 0.000
M81.5 Idiopathic osteoporosis
0.701 0.299 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.701 0.299 0.000
M81.2 Osteoporosis of disuse
0.701 0.299 0.000
M81.1 Postoophorectomy osteoporosis
0.701 0.299 0.000
M81.0 Postmenopausal osteoporosis
0.701 0.299 0.000
M79.9 Soft tissue disorder, unspecified
0.701 0.299 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.701 0.299 0.000
M79.3 Panniculitis, unspecified
0.701 0.299 0.000
M79.2 Neuralgia and neuritis, unspecified
0.701 0.299 0.000
L50-L54 Urticaria and erythema
0.701 0.299 0.000
M65.3 Trigger finger
0.700 0.299 0.000
N83.1 Corpus luteum cyst
0.700 0.300 0.000
G71 Primary disorders of muscles
0.699 0.301 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.698 0.302 0.000
C04 Malignant neoplasm of floor of mouth
0.698 0.302 0.000
D30.0 Kidney
0.698 0.302 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.696 0.304 0.000
G41 Status epilepticus
0.696 0.304 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.696 0.304 0.000
L89 Decubitus ulcer
0.696 0.304 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.696 0.304 0.000
L71 Rosacea
0.694 0.306 0.000
D23.3 Skin of other and unspecified parts of face
0.694 0.306 0.000
I05 Rheumatic mitral valve diseases
0.693 0.306 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.693 0.307 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.693 0.307 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.693 0.307 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.693 0.307 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.693 0.307 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.693 0.307 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.692 0.308 0.000
D41.4 Bladder
0.692 0.308 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.691 0.308 0.000
F32.9 Depressive episode, unspecified
0.691 0.309 0.000
N60.8 Other benign mammary dysplasias
0.690 0.310 0.000
N97.9 Female infertility, unspecified
0.689 0.311 0.000
I85 Oesophageal varices
0.687 0.313 0.000
G72 Other myopathies
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.686 0.314 0.000
G47.8 Other sleep disorders
0.685 0.315 0.000
G47.4 Narcolepsy and cataplexy
0.685 0.315 0.000
G47.2 Disorders of the sleep-wake schedule
0.685 0.315 0.000
S32 Fracture of lumbar spine and pelvis
0.684 0.316 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.316 0.000
E34 Other endocrine disorders
0.683 0.316 0.000
E32 Diseases of thymus
0.683 0.316 0.000
E31 Polyglandular dysfunction
0.683 0.316 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.316 0.000
E26 Hyperaldosteronism
0.683 0.316 0.000
E25 Adrenogenital disorders
0.683 0.316 0.000
E24 Cushing's syndrome
0.683 0.316 0.000
E20 Hypoparathyroidism
0.683 0.316 0.000
M67.8 Other specified disorders of synovium and tendon
0.683 0.317 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.682 0.318 0.000
Q23 Congenital malformations of aortic and mitral valves
0.682 0.318 0.000
G44.2 Tension-type headache
0.682 0.318 0.000
C77.8 Lymph nodes of multiple regions
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.681 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.681 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.681 0.318 0.000
G51.0 Bell's palsy
0.681 0.319 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.681 0.319 0.000
L94 Other localised connective tissue disorders
0.681 0.319 0.000
L93 Lupus erythematosus
0.681 0.319 0.000
L87 Transepidermal elimination disorders
0.681 0.319 0.000
L88 Pyoderma gangrenosum
0.681 0.319 0.000
L86 Keratoderma in diseases classified elsewhere
0.681 0.319 0.000
E21.3 Hyperparathyroidism, unspecified
0.680 0.320 0.000
S70-S79 Injuries to the hip and thigh
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
N60.2 Fibroadenosis of breast
0.679 0.321 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.678 0.322 0.000
C21 Malignant neoplasm of anus and anal canal
0.678 0.322 0.000
C23 Malignant neoplasm of gallbladder
0.678 0.322 0.000
D33.3 Cranial nerves
0.678 0.322 0.000
M79.64 Pain in limb (Hand)
0.677 0.323 0.000
N90.5 Atrophy of vulva
0.677 0.323 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.677 0.323 0.000
L75 Apocrine sweat disorders
0.675 0.325 0.000
L74 Eccrine sweat disorders
0.675 0.325 0.000
L70 Acne
0.675 0.325 0.000
L68 Hypertrichosis
0.675 0.325 0.000
L67 Hair colour and hair shaft abnormalities
0.675 0.325 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.675 0.325 0.000
L65 Other nonscarring hair loss
0.675 0.325 0.000
L64 Androgenic alopecia
0.675 0.325 0.000
L63 Alopecia areata
0.675 0.325 0.000
L62 Nail disorders in diseases classified elsewhere
0.675 0.325 0.000
D09 Carcinoma in situ of other and unspecified sites
0.675 0.325 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.675 0.325 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.675 0.325 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.675 0.325 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.674 0.326 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.326 0.000
E27.1 Primary adrenocortical insufficiency
0.674 0.326 0.000
T66-T78 Other and unspecified effects of external causes
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
M43 Other deforming dorsopathies
0.672 0.328 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.672 0.328 0.000
D33.2 Brain, unspecified
0.670 0.330 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.670 0.330 0.000
D31.0 Conjunctiva
0.669 0.331 0.000
E28 Ovarian dysfunction
0.669 0.331 0.000
H10-H13 Disorders of conjunctiva
0.668 0.331 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.667 0.333 0.000
M79.78 Fibromyalgia (Other)
0.667 0.333 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.667 0.333 0.000
M79.76 Fibromyalgia (Lower leg)
0.667 0.333 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.667 0.333 0.000
M79.74 Fibromyalgia (Hand)
0.667 0.333 0.000
M79.73 Fibromyalgia (Forearm)
0.667 0.333 0.000
M79.72 Fibromyalgia (Upper arm)
0.667 0.333 0.000
M79.71 Fibromyalgia (Shoulder region)
0.667 0.333 0.000
M79.70 Fibromyalgia (Multiple sites)
0.667 0.333 0.000
C50-C50 Malignant neoplasm of breast
0.667 0.333 0.000
G70 Myasthenia gravis and other myoneural disorders
0.667 0.333 0.000
M05-M14 Inflammatory polyarthropathies
0.666 0.334 0.000
M84.0 Malunion of fracture
0.666 0.334 0.000
E70-E90 Metabolic disorders
0.666 0.334 0.000
C45 Mesothelioma
0.666 0.334 0.000
G61 Inflammatory polyneuropathy
0.664 0.336 0.000
M65.2 Calcific tendinitis
0.662 0.337 0.000
M65.1 Other infective (teno)synovitis
0.662 0.337 0.000
M65.0 Abscess of tendon sheath
0.662 0.337 0.000
L60 Nail disorders
0.661 0.339 0.000
E03.9 Hypothyroidism, unspecified
0.661 0.339 0.000
L81 Other disorders of pigmentation
0.660 0.340 0.000
C32 Malignant neoplasm of larynx
0.660 0.340 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.659 0.341 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.659 0.341 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.658 0.342 0.000
F43 Reaction to severe stress, and adjustment disorders
0.658 0.342 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.658 0.342 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.658 0.342 0.000
C81 Hodgkin's disease
0.658 0.342 0.000
E65 Localised adiposity
0.657 0.343 0.000
D45 Polycythaemia vera
0.655 0.345 0.000
N18.5 Chronic kidney disease, stage 5
0.655 0.345 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.653 0.347 0.000
E40-E46 Malnutrition
0.653 0.347 0.000
N64.8 Other specified disorders of breast
0.652 0.348 0.000
D04.6 Skin of upper limb, including shoulder
0.651 0.349 0.000
S90.8 Other superficial injuries of ankle and foot
0.651 0.349 0.000
S10-S19 Injuries to the neck
0.650 0.349 0.000
G20-G26 Extrapyramidal and movement disorders
0.650 0.350 0.000
H40.0 Glaucoma suspect
0.650 0.350 0.000
T92 Sequelae of injuries of upper limb
0.649 0.351 0.000
L72.2 Steatocystoma multiplex
0.649 0.351 0.000
D26 Other benign neoplasms of uterus
0.647 0.353 0.000
N03 Chronic nephritic syndrome
0.646 0.353 0.000
T31 Burns classified according to extent of body surface involved
0.646 0.354 0.000
H02.1 Ectropion of eyelid
0.646 0.354 0.000
E10-E14 Diabetes mellitus
0.646 0.354 0.000
E50-E64 Other nutritional deficiencies
0.645 0.355 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.645 0.355 0.000
N80.9 Endometriosis, unspecified
0.644 0.356 0.000
M71.9 Bursopathy, unspecified
0.643 0.357 0.000
M71.8 Other specified bursopathies
0.643 0.357 0.000
M71.5 Other bursitis, not elsewhere classified
0.643 0.357 0.000
M71.4 Calcium deposit in bursa
0.643 0.357 0.000
M71.3 Other bursal cyst
0.643 0.357 0.000
M71.1 Other infective bursitis
0.643 0.357 0.000
M71.0 Abscess of bursa
0.643 0.357 0.000
E29 Testicular dysfunction
0.642 0.357 0.000
M84.9 Disorder of continuity of bone, unspecified
0.642 0.358 0.000
M84.8 Other disorders of continuity of bone
0.642 0.358 0.000
M84.4 Pathological fracture, not elsewhere classified
0.642 0.358 0.000
M84.3 Stress fracture, not elsewhere classified
0.642 0.358 0.000
M84.2 Delayed union of fracture
0.642 0.358 0.000
B25-B34 Other viral diseases
0.642 0.358 0.000
N90.4 Leukoplakia of vulva
0.641 0.359 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.639 0.361 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.639 0.361 0.000
I85.9 Oesophageal varices without bleeding
0.639 0.361 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.639 0.361 0.000
F60-F69 Disorders of adult personality and behaviour
0.638 0.362 0.000
N83.0 Follicular cyst of ovary
0.638 0.362 0.000
D73 Diseases of spleen
0.637 0.363 0.000
G45.3 Amaurosis fugax
0.637 0.363 0.000
L73.2 Hidradenitis suppurativa
0.637 0.363 0.000
N60.1 Diffuse cystic mastopathy
0.637 0.363 0.000
E06 Thyroiditis
0.637 0.363 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.636 0.364 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.635 0.364 0.000
C91 Lymphoid leukaemia
0.635 0.365 0.000
N13 Obstructive and reflux uropathy
0.635 0.365 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.635 0.365 0.000
B00 Herpesviral [herpes simplex] infections
0.634 0.366 0.000
S91 Open wound of ankle and foot
0.633 0.367 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.633 0.367 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.633 0.367 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.632 0.368 0.000
I00-I02 Acute rheumatic fever
0.631 0.369 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.631 0.369 0.000
L40-L45 Papulosquamous disorders
0.631 0.369 0.000
D05 Carcinoma in situ of breast
0.631 0.369 0.000
E27.5 Adrenomedullary hyperfunction
0.630 0.369 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.630 0.369 0.000
E27.2 Addisonian crisis
0.630 0.369 0.000
E27.0 Other adrenocortical overactivity
0.630 0.369 0.000
H02.8 Other specified disorders of eyelid
0.630 0.369 0.000
T33-T35 Frostbite
0.630 0.369 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.630 0.369 0.000
F99-F99 Unspecified mental disorder
0.630 0.370 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.629 0.371 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.628 0.372 0.000
E21.4 Other specified disorders of parathyroid gland
0.628 0.372 0.000
E21.2 Other hyperparathyroidism
0.628 0.372 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.628 0.372 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.628 0.372 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.628 0.372 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.628 0.372 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.628 0.372 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.628 0.372 0.000
C34.9 Bronchus or lung, unspecified
0.628 0.372 0.000
S50-S59 Injuries to the elbow and forearm
0.626 0.374 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.625 0.375 0.000
D36.0 Lymph nodes
0.624 0.376 0.000
M77 Other enthesopathies
0.623 0.377 0.000
G60 Hereditary and idiopathic neuropathy
0.623 0.377 0.000
F31.9 Bipolar affective disorder, unspecified
0.623 0.377 0.000
C92 Myeloid leukaemia
0.622 0.378 0.000
N89 Other noninflammatory disorders of vagina
0.622 0.378 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.622 0.378 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.622 0.378 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.621 0.379 0.000
C13 Malignant neoplasm of hypopharynx
0.621 0.379 0.000
C11 Malignant neoplasm of nasopharynx
0.621 0.379 0.000
C10 Malignant neoplasm of oropharynx
0.621 0.379 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.621 0.379 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.621 0.379 0.000
C05 Malignant neoplasm of palate
0.621 0.379 0.000
C03 Malignant neoplasm of gum
0.621 0.379 0.000
C00 Malignant neoplasm of lip
0.621 0.379 0.000
C12 Malignant neoplasm of pyriform sinus
0.621 0.379 0.000
C07 Malignant neoplasm of parotid gland
0.621 0.379 0.000
C25.1 Body of pancreas
0.621 0.379 0.000
D06.7 Other parts of cervix
0.621 0.379 0.000
D06.1 Exocervix
0.621 0.379 0.000
D06.0 Endocervix
0.621 0.379 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.621 0.379 0.000
C95 Leukaemia of unspecified cell type
0.621 0.379 0.000
C94 Other leukaemias of specified cell type
0.621 0.379 0.000
C93 Monocytic leukaemia
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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