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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75222977
log Bayes Factor = 16.5267
Chromosome 1   position 172,235,394  (GRCh37) Explore rs75222977 on Ensembl!
Variant rs75222977 is part of Cluster X0001

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.994 0.006 0.000
M54 Dorsalgia
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
M70-M79 Other soft tissue disorders
0.989 0.011 0.000
Z87 Personal history of other diseases and conditions
0.988 0.012 0.000
M54.5 Low back pain
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.979 0.021 0.000
K08 Other disorders of teeth and supporting structures
0.978 0.022 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.973 0.027 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
M54.56 Low back pain (Lumbar region)
0.967 0.033 0.000
S00-S09 Injuries to the head
0.965 0.035 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.965 0.035 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.963 0.037 0.000
K30 Dyspepsia
0.962 0.038 0.000
M25 Other joint disorders, not elsewhere classified
0.962 0.038 0.000
M15-M19 Arthrosis
0.957 0.043 0.000
M79.6 Pain in limb
0.956 0.044 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.951 0.049 0.000
K29 Gastritis and duodenitis
0.951 0.049 0.000
M54.9 Dorsalgia, unspecified
0.950 0.050 0.000
I10-I15 Hypertensive diseases
0.950 0.050 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.946 0.054 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.945 0.055 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.939 0.061 0.000
Z87.1 Personal history of diseases of the digestive system
0.939 0.061 0.000
Z03.4 Observation for suspected myocardial infarction
0.936 0.064 0.000
Chapter XIV Diseases of the genitourinary system
0.931 0.069 0.000
M19 Other arthrosis
0.930 0.070 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.926 0.074 0.000
I10 Essential (primary) hypertension
0.924 0.076 0.000
K14 Diseases of tongue
0.924 0.076 0.000
K29.8 Duodenitis
0.924 0.076 0.000
M25.5 Pain in joint
0.923 0.077 0.000
Z95.0 Presence of cardiac pacemaker
0.923 0.077 0.000
M79.66 Pain in limb (Lower leg)
0.919 0.081 0.000
I50 Heart failure
0.918 0.082 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.915 0.085 0.000
M45-M49 Spondylopathies
0.915 0.085 0.000
K35-K38 Diseases of appendix
0.914 0.086 0.000
M54.59 Low back pain (Site unspecified)
0.913 0.087 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.909 0.091 0.000
N40-N51 Diseases of male genital organs
0.906 0.094 0.000
F30-F39 Mood [affective] disorders
0.904 0.096 0.000
Chapter I Certain infectious and parasitic diseases
0.903 0.097 0.000
Z95.4 Presence of other heart-valve replacement
0.901 0.099 0.000
K26 Duodenal ulcer
0.900 0.100 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.900 0.100 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.900 0.100 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.898 0.102 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.897 0.103 0.000
M19.9 Arthrosis, unspecified
0.896 0.104 0.000
M65-M68 Disorders of synovium and tendon
0.891 0.109 0.000
S06 Intracranial injury
0.887 0.113 0.000
Z50 Care involving use of rehabilitation procedures
0.884 0.116 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.882 0.118 0.000
I47 Paroxysmal tachycardia
0.877 0.123 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
K01 Embedded and impacted teeth
0.872 0.128 0.000
N50 Other disorders of male genital organs
0.872 0.128 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.871 0.129 0.000
Z95.2 Presence of prosthetic heart valve
0.869 0.131 0.000
M25.56 Pain in joint (Lower leg)
0.869 0.131 0.000
I74 Arterial embolism and thrombosis
0.867 0.133 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.865 0.135 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.861 0.139 0.000
Z02 Examination and encounter for administrative purposes
0.859 0.141 0.000
N41 Inflammatory diseases of prostate
0.856 0.144 0.000
K09 Cysts of oral region, not elsewhere classified
0.856 0.144 0.000
Chapter VII Diseases of the eye and adnexa
0.855 0.145 0.000
K08.3 Retained dental root
0.854 0.146 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.850 0.150 0.000
M40-M43 Deforming dorsopathies
0.849 0.151 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.849 0.151 0.000
K14.8 Other diseases of tongue
0.848 0.152 0.000
S40-S49 Injuries to the shoulder and upper arm
0.844 0.156 0.000
A00-A09 Intestinal infectious diseases
0.844 0.156 0.000
F33 Recurrent depressive disorder
0.842 0.158 0.000
N60-N64 Disorders of breast
0.840 0.160 0.000
A30-A49 Other bacterial diseases
0.839 0.161 0.000
S90-S99 Injuries to the ankle and foot
0.838 0.162 0.000
I50.0 Congestive heart failure
0.836 0.164 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.835 0.165 0.000
M75 Shoulder lesions
0.835 0.165 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.834 0.166 0.000
I35 Nonrheumatic aortic valve disorders
0.834 0.166 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.833 0.167 0.000
S00 Superficial injury of head
0.833 0.167 0.000
K35 Acute appendicitis
0.833 0.167 0.000
I49 Other cardiac arrhythmias
0.832 0.167 0.000
Z03.8 Observation for other suspected diseases and conditions
0.832 0.168 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.831 0.169 0.000
H30-H36 Disorders of choroid and retina
0.827 0.173 0.000
M79.60 Pain in limb (Multiple sites)
0.826 0.174 0.000
Z34 Supervision of normal pregnancy
0.825 0.175 0.000
A04 Other bacterial intestinal infections
0.822 0.178 0.000
K29.0 Acute haemorrhagic gastritis
0.821 0.179 0.000
N41.1 Chronic prostatitis
0.821 0.179 0.000
M25.8 Other specified joint disorders
0.821 0.179 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.818 0.181 0.000
M18 Arthrosis of first carpometacarpal joint
0.816 0.184 0.000
K05 Gingivitis and periodontal diseases
0.815 0.185 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.813 0.187 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.813 0.187 0.000
M25.57 Pain in joint (Ankle and foot)
0.812 0.188 0.000
M21 Other acquired deformities of limbs
0.810 0.189 0.000
Z81 Family history of mental and behavioural disorders
0.808 0.192 0.000
K07 Dentofacial anomalies [including malocclusion]
0.808 0.192 0.000
M25.7 Osteophyte
0.808 0.192 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.806 0.194 0.000
A04.8 Other specified bacterial intestinal infections
0.806 0.194 0.000
N50.8 Other specified disorders of male genital organs
0.804 0.196 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.803 0.197 0.000
M47 Spondylosis
0.802 0.198 0.000
I50.1 Left ventricular failure
0.801 0.199 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.799 0.201 0.000
M79.8 Other specified soft tissue disorders
0.797 0.203 0.000
H35 Other retinal disorders
0.796 0.204 0.000
Z88.5 Personal history of allergy to narcotic agent
0.796 0.204 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.792 0.208 0.000
Y86 Sequelae of other accidents
0.791 0.209 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.791 0.209 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.791 0.209 0.000
K27 Peptic ulcer, site unspecified
0.790 0.210 0.000
Z50.0 Cardiac rehabilitation
0.790 0.210 0.000
Y52 Agents primarily affecting the cardiovascular system
0.790 0.210 0.000
M48 Other spondylopathies
0.789 0.211 0.000
I73 Other peripheral vascular diseases
0.788 0.212 0.000
W20-W49 Exposure to inanimate mechanical forces
0.787 0.213 0.000
M91-M94 Chondropathies
0.785 0.215 0.000
K01.1 Impacted teeth
0.782 0.218 0.000
Z40 Prophylactic surgery
0.782 0.218 0.000
S02 Fracture of skull and facial bones
0.782 0.218 0.000
S80-S89 Injuries to the knee and lower leg
0.781 0.219 0.000
N50.1 Vascular disorders of male genital organs
0.780 0.220 0.000
M65 Synovitis and tenosynovitis
0.778 0.222 0.000
K12 Stomatitis and related lesions
0.778 0.222 0.000
Z94 Transplanted organ and tissue status
0.777 0.223 0.000
M34 Systemic sclerosis
0.777 0.223 0.000
M51 Other intervertebral disk disorders
0.777 0.223 0.000
S01 Open wound of head
0.776 0.224 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.774 0.226 0.000
I47.2 Ventricular tachycardia
0.772 0.228 0.000
Z42 Follow-up care involving plastic surgery
0.772 0.228 0.000
Z13 Special screening examination for other diseases and disorders
0.771 0.229 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.768 0.232 0.000
I44 Atrioventricular and left bundle-branch block
0.767 0.233 0.000
M54.4 Lumbago with sciatica
0.765 0.235 0.000
Z02.8 Other examinations for administrative purposes
0.763 0.237 0.000
M35 Other systemic involvement of connective tissue
0.762 0.238 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.762 0.238 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.762 0.238 0.000
Z80 Family history of malignant neoplasm
0.762 0.238 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.762 0.238 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.761 0.239 0.000
M22 Disorders of patella
0.760 0.240 0.000
Z33 Pregnant state, incidental
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.760 0.240 0.000
K29.1 Other acute gastritis
0.759 0.241 0.000
M19.0 Primary arthrosis of other joints
0.758 0.242 0.000
Z50.2 Alcohol rehabilitation
0.758 0.242 0.000
I37 Pulmonary valve disorders
0.757 0.243 0.000
I20-I25 Ischaemic heart diseases
0.757 0.243 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.757 0.243 0.000
I31 Other diseases of pericardium
0.757 0.243 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.757 0.243 0.000
F99-F99 Unspecified mental disorder
0.756 0.244 0.000
S06.5 Traumatic subdural haemorrhage
0.756 0.244 0.000
M25.59 Pain in joint (Site unspecified)
0.756 0.244 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.755 0.245 0.000
H35.3 Degeneration of macula and posterior pole
0.755 0.245 0.000
M24 Other specific joint derangements
0.754 0.246 0.000
M79.63 Pain in limb (Forearm)
0.754 0.246 0.000
Z89 Acquired absence of limb
0.754 0.246 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.752 0.248 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.750 0.250 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.750 0.250 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.749 0.251 0.000
N63 Unspecified lump in breast
0.749 0.251 0.000
N99-N99 Other disorders of the genitourinary system
0.747 0.252 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.747 0.253 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.746 0.254 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.745 0.255 0.000
N10-N16 Renal tubulo-interstitial diseases
0.743 0.257 0.000
M77 Other enthesopathies
0.743 0.257 0.000
K14.0 Glossitis
0.743 0.257 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
Z03.3 Observation for suspected nervous system disorder
0.742 0.258 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.741 0.259 0.000
M79.64 Pain in limb (Hand)
0.740 0.260 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.740 0.260 0.000
M16 Coxarthrosis [arthrosis of hip]
0.738 0.262 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.738 0.262 0.000
I36 Nonrheumatic tricuspid valve disorders
0.736 0.264 0.000
Y44 Agents primarily affecting blood constituents
0.736 0.264 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.736 0.264 0.000
N45 Orchitis and epididymitis
0.735 0.265 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.735 0.265 0.000
A49 Bacterial infection of unspecified site
0.734 0.266 0.000
Z34.8 Supervision of other normal pregnancy
0.734 0.266 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.734 0.266 0.000
K38 Other diseases of appendix
0.734 0.266 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.732 0.268 0.000
K50-K52 Noninfective enteritis and colitis
0.732 0.268 0.000
N25-N29 Other disorders of kidney and ureter
0.731 0.269 0.000
I46 Cardiac arrest
0.731 0.269 0.000
S06.3 Focal brain injury
0.731 0.269 0.000
N20-N23 Urolithiasis
0.731 0.269 0.000
F33.9 Recurrent depressive disorder, unspecified
0.730 0.270 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.730 0.270 0.000
Z98 Other postsurgical states
0.730 0.270 0.000
M79.1 Myalgia
0.730 0.270 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.729 0.271 0.000
K10 Other diseases of jaws
0.729 0.271 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.728 0.272 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.275 0.000
Z35 Supervision of high-risk pregnancy
0.723 0.277 0.000
I49.9 Cardiac arrhythmia, unspecified
0.723 0.277 0.000
Z12 Special screening examination for neoplasms
0.722 0.278 0.000
M71 Other bursopathies
0.718 0.282 0.000
F32 Depressive episode
0.718 0.282 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.718 0.282 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N60 Benign mammary dysplasia
0.716 0.284 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.716 0.284 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.715 0.285 0.000
K03 Other diseases of hard tissues of teeth
0.715 0.285 0.000
K00 Disorders of tooth development and eruption
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
M75.9 Shoulder lesion, unspecified
0.714 0.286 0.000
K04 Diseases of pulp and periapical tissues
0.714 0.286 0.000
S20-S29 Injuries to the thorax
0.714 0.286 0.000
S70-S79 Injuries to the hip and thigh
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.287 0.000
L40-L45 Papulosquamous disorders
0.713 0.287 0.000
Z41 Procedures for purposes other than remedying health state
0.712 0.287 0.000
M54.8 Other dorsalgia
0.712 0.288 0.000
M54.6 Pain in thoracic spine
0.712 0.288 0.000
M54.0 Panniculitis affecting regions of neck and back
0.712 0.288 0.000
K86 Other diseases of pancreas
0.712 0.288 0.000
Z50.8 Care involving use of rehabilitation procedures
0.712 0.288 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.711 0.289 0.000
M47.9 Spondylosis, unspecified
0.711 0.289 0.000
Z50.1 Other physical therapy
0.711 0.289 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.711 0.289 0.000
M86-M90 Other osteopathies
0.710 0.290 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.710 0.290 0.000
Z95.1 Presence of aortocoronary bypass graft
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
I71 Aortic aneurysm and dissection
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
S10-S19 Injuries to the neck
0.709 0.291 0.000
N40 Hyperplasia of prostate
0.709 0.291 0.000
S80 Superficial injury of lower leg
0.709 0.291 0.000
M76 Enthesopathies of lower limb, excluding foot
0.709 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.709 0.291 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.708 0.292 0.000
A40 Streptococcal septicaemia
0.708 0.292 0.000
M25.52 Pain in joint (Upper arm)
0.707 0.293 0.000
M54.55 Low back pain (Thoracolumbar region)
0.707 0.293 0.000
M54.54 Low back pain-Thoracic
0.707 0.293 0.000
M54.53 Low back pain-Cervicothoracic
0.707 0.293 0.000
M54.52 Low back pain-Cervical
0.707 0.293 0.000
M54.51 Low back pain-Occipit-atl-axl
0.707 0.293 0.000
M54.50 Low back pain (Multiple sites in spine)
0.707 0.293 0.000
M19.1 Posttraumatic arthrosis of other joints
0.706 0.294 0.000
S06.0 Concussion
0.706 0.294 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.705 0.295 0.000
M43 Other deforming dorsopathies
0.705 0.295 0.000
K80 Cholelithiasis
0.705 0.295 0.000
F17.1 Harmful use
0.705 0.295 0.000
I27 Other pulmonary heart diseases
0.704 0.296 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.704 0.296 0.000
S09 Other and unspecified injuries of head
0.704 0.296 0.000
K81 Cholecystitis
0.703 0.297 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.703 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I33 Acute and subacute endocarditis
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
Z32 Pregnancy examination and test
0.702 0.298 0.000
K28 Gastrojejunal ulcer
0.702 0.298 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.702 0.298 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.702 0.298 0.000
L40 Psoriasis
0.701 0.299 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.701 0.299 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.299 0.000
I49.5 Sick sinus syndrome
0.700 0.300 0.000
I78 Diseases of capillaries
0.699 0.301 0.000
M25.76 Osteophyte (Lower leg)
0.699 0.301 0.000
S00.0 Superficial injury of scalp
0.698 0.302 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.698 0.302 0.000
I72 Other aneurysm
0.698 0.302 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.697 0.303 0.000
F70-F79 Mental retardation
0.697 0.303 0.000
F60-F69 Disorders of adult personality and behaviour
0.697 0.303 0.000
I73.9 Peripheral vascular disease, unspecified
0.697 0.303 0.000
I95 Hypotension
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.696 0.304 0.000
N41.0 Acute prostatitis
0.696 0.304 0.000
M79.9 Soft tissue disorder, unspecified
0.695 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.695 0.304 0.000
M79.3 Panniculitis, unspecified
0.695 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.695 0.304 0.000
M19.94 Arthrosis, unspecified (Hand)
0.695 0.304 0.000
Z57 Occupational exposure to risk-factors
0.695 0.305 0.000
T79-T79 Certain early complications of trauma
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
M79.67 Pain in limb (Ankle and foot)
0.694 0.306 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.694 0.306 0.000
Y43 Primarily systemic agents
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.694 0.306 0.000
Q60-Q64 Congenital malformations of the urinary system
0.694 0.306 0.000
Z31 Procreative management
0.693 0.307 0.000
S00.8 Superficial injury of other parts of head
0.693 0.307 0.000
M79.5 Residual foreign body in soft tissue
0.692 0.308 0.000
S08 Traumatic amputation of part of head
0.692 0.308 0.000
S07 Crushing injury of head
0.692 0.308 0.000
S05 Injury of eye and orbit
0.692 0.308 0.000
S04 Injury of cranial nerves
0.692 0.308 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.692 0.308 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.692 0.308 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.692 0.308 0.000
Z03.0 Observation for suspected tuberculosis
0.692 0.308 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.692 0.308 0.000
Z95.3 Presence of xenogenic heart valve
0.691 0.309 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.690 0.310 0.000
M25.9 Joint disorder, unspecified
0.690 0.310 0.000
M25.3 Other instability of joint
0.690 0.310 0.000
M25.2 Flail joint
0.690 0.310 0.000
M25.1 Fistula of joint
0.690 0.310 0.000
M25.0 Haemarthrosis
0.690 0.310 0.000
M79.69 Pain in limb (Site unspecified)
0.690 0.310 0.000
F80-F89 Disorders of psychological development
0.689 0.311 0.000
A04.5 Campylobacter enteritis
0.689 0.311 0.000
Z64 Problems related to certain psychosocial circumstances
0.687 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.687 0.313 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.687 0.313 0.000
M15 Polyarthrosis
0.686 0.314 0.000
M31 Other necrotising vasculopathies
0.686 0.314 0.000
M79.68 Pain in limb (Other)
0.685 0.314 0.000
M79.61 Pain in limb (Shoulder region)
0.685 0.314 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.686 0.314 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.685 0.315 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.685 0.315 0.000
K09.0 Developmental odontogenic cysts
0.685 0.315 0.000
K05.3 Chronic periodontitis
0.684 0.316 0.000
L40.9 Psoriasis, unspecified
0.684 0.316 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.683 0.317 0.000
M75.3 Calcific tendinitis of shoulder
0.683 0.317 0.000
M67 Other disorders of synovium and tendon
0.683 0.317 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.682 0.318 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.682 0.318 0.000
K29.9 Gastroduodenitis, unspecified
0.682 0.318 0.000
K29.2 Alcoholic gastritis
0.682 0.318 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.682 0.318 0.000
M54.1 Radiculopathy
0.681 0.319 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.681 0.319 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.681 0.319 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.681 0.319 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.681 0.319 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.681 0.319 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.681 0.319 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.681 0.319 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.681 0.319 0.000
S01.0 Open wound of scalp
0.681 0.319 0.000
I15 Secondary hypertension
0.681 0.319 0.000
I13 Hypertensive heart and renal disease
0.681 0.319 0.000
I11 Hypertensive heart disease
0.681 0.319 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.680 0.320 0.000
M66 Spontaneous rupture of synovium and tendon
0.680 0.320 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.679 0.321 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.678 0.322 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.677 0.323 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.676 0.324 0.000
Z03.1 Observation for suspected malignant neoplasm
0.675 0.325 0.000
K29.3 Chronic superficial gastritis
0.674 0.326 0.000
S92 Fracture of foot, except ankle
0.674 0.326 0.000
V10-V19 Pedal cyclist injured in transport accident
0.674 0.326 0.000
Y59 Other and unspecified vaccines and biological substances
0.673 0.326 0.000
Y58 Bacterial vaccines
0.673 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.673 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.673 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.673 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.673 0.326 0.000
Y48 Anaesthetics and therapeutic gases
0.673 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.673 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.673 0.326 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.673 0.327 0.000
Z81.8 Family history of other mental and behavioural disorders
0.673 0.327 0.000
I35.1 Aortic (valve) insufficiency
0.672 0.328 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.672 0.328 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.672 0.328 0.000
I77 Other disorders of arteries and arterioles
0.671 0.329 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.671 0.329 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.670 0.330 0.000
M41 Scoliosis
0.669 0.331 0.000
M21.1 Varus deformity, not elsewhere classified
0.667 0.333 0.000
M19.8 Other specified arthrosis
0.667 0.333 0.000
M19.2 Other secondary arthrosis
0.667 0.333 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.667 0.333 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.667 0.333 0.000
M72 Fibroblastic disorders
0.666 0.334 0.000
I70 Atherosclerosis
0.666 0.334 0.000
M35.3 Polymyalgia rheumatica
0.666 0.334 0.000
W22 Striking against or struck by other objects
0.665 0.335 0.000
M16.0 Primary coxarthrosis, bilateral
0.664 0.336 0.000
K11 Diseases of salivary glands
0.664 0.336 0.000
F10.2 Dependence syndrome
0.664 0.336 0.000
K07.6 Temporomandibular joint disorders
0.663 0.337 0.000
K14.6 Glossodynia
0.662 0.338 0.000
K14.5 Plicated tongue
0.662 0.338 0.000
K14.4 Atrophy of tongue papillae
0.662 0.338 0.000
K14.3 Hypertrophy of tongue papillae
0.662 0.338 0.000
K14.2 Median rhomboid glossitis
0.662 0.338 0.000
K14.1 Geographic tongue
0.662 0.338 0.000
M25.58 Pain in joint (Other)
0.662 0.338 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.662 0.338 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.660 0.340 0.000
I45 Other conduction disorders
0.660 0.340 0.000
Z49 Care involving dialysis
0.660 0.340 0.000
Z91.6 Personal history of other physical trauma
0.659 0.341 0.000
K14.9 Disease of tongue, unspecified
0.659 0.341 0.000
H35.6 Retinal haemorrhage
0.658 0.342 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.657 0.343 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.657 0.343 0.000
H34 Retinal vascular occlusions
0.657 0.343 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.657 0.343 0.000
M48.0 Spinal stenosis
0.657 0.343 0.000
Z54 Convalescence
0.656 0.344 0.000
Z52 Donors of organs and tissues
0.656 0.344 0.000
Z44 Fitting and adjustment of external prosthetic device
0.656 0.344 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.656 0.344 0.000
M49 Spondylopathies in diseases classified elsewhere
0.656 0.344 0.000
K36 Other appendicitis
0.655 0.345 0.000
Y45.0 Opioids and related analgesics
0.655 0.345 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.655 0.345 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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