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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75238399
log Bayes Factor = 16.75
Chromosome 2   position 126,960,737  (GRCh37) Explore rs75238399 on Ensembl!
Variant rs75238399 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I63 Cerebral infarction
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
I63.9 Cerebral infarction, unspecified
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I69 Sequelae of cerebrovascular disease
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.992 0.008 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.987 0.013 0.000
I67 Other cerebrovascular diseases
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.979 0.021 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.978 0.022 0.000
D69 Purpura and other haemorrhagic conditions
0.977 0.023 0.000
Chapter VII Diseases of the eye and adnexa
0.975 0.025 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.972 0.028 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
T81 Complications of procedures, not elsewhere classified
0.962 0.038 0.000
D69.6 Thrombocytopenia, unspecified
0.955 0.045 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.953 0.047 0.000
Chapter VI Diseases of the nervous system
0.949 0.051 0.000
M75 Shoulder lesions
0.947 0.053 0.000
I71 Aortic aneurysm and dissection
0.943 0.057 0.000
M79.8 Other specified soft tissue disorders
0.943 0.057 0.000
Chapter II Neoplasms
0.936 0.064 0.000
Y43 Primarily systemic agents
0.931 0.069 0.000
I67.9 Cerebrovascular disease, unspecified
0.929 0.071 0.000
I69.3 Sequelae of cerebral infarction
0.928 0.072 0.000
M05-M14 Inflammatory polyarthropathies
0.926 0.074 0.000
H53-H54 Visual disturbances and blindness
0.919 0.081 0.000
S01 Open wound of head
0.919 0.081 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.917 0.083 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.908 0.092 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.905 0.095 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.901 0.099 0.000
D70 Agranulocytosis
0.899 0.101 0.000
Y43.3 Other antineoplastic drugs
0.896 0.104 0.000
M79.0 Rheumatism, unspecified
0.895 0.105 0.000
Chapter X Diseases of the respiratory system
0.894 0.106 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.893 0.107 0.000
D75 Other diseases of blood and blood-forming organs
0.891 0.109 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.891 0.109 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
S40-S49 Injuries to the shoulder and upper arm
0.889 0.111 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.887 0.113 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
M45-M49 Spondylopathies
0.884 0.116 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.880 0.120 0.000
G81 Hemiplegia
0.880 0.120 0.000
I67.8 Other specified cerebrovascular diseases
0.877 0.123 0.000
M75.5 Bursitis of shoulder
0.875 0.125 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.872 0.128 0.000
I74 Arterial embolism and thrombosis
0.870 0.130 0.000
M79.7 Fibromyalgia
0.867 0.133 0.000
T79-T79 Certain early complications of trauma
0.860 0.140 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.860 0.140 0.000
G81.9 Hemiplegia, unspecified
0.859 0.141 0.000
A30-A49 Other bacterial diseases
0.857 0.143 0.000
I80 Phlebitis and thrombophlebitis
0.855 0.144 0.000
I63.8 Other cerebral infarction
0.854 0.146 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.850 0.150 0.000
C15-C26 Malignant neoplasms of digestive organs
0.846 0.154 0.000
S01.1 Open wound of eyelid and periocular area
0.846 0.154 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.843 0.157 0.000
A41 Other septicaemia
0.842 0.158 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.841 0.159 0.000
M06 Other rheumatoid arthritis
0.838 0.162 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.838 0.162 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.837 0.163 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.835 0.165 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.835 0.165 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.834 0.166 0.000
S01.9 Open wound of head, part unspecified
0.833 0.167 0.000
M75.4 Impingement syndrome of shoulder
0.831 0.169 0.000
M79.1 Myalgia
0.831 0.169 0.000
Y86 Sequelae of other accidents
0.830 0.170 0.000
S10-S19 Injuries to the neck
0.827 0.173 0.000
A41.9 Septicaemia, unspecified
0.823 0.177 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.822 0.178 0.000
H53 Visual disturbances
0.822 0.178 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.819 0.181 0.000
C79 Secondary malignant neoplasm of other sites
0.819 0.181 0.000
D00-D09 In situ neoplasms
0.818 0.182 0.000
H54 Blindness and low vision
0.813 0.187 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.812 0.188 0.000
S60-S69 Injuries to the wrist and hand
0.811 0.189 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.809 0.191 0.000
M75.3 Calcific tendinitis of shoulder
0.809 0.191 0.000
W20-W49 Exposure to inanimate mechanical forces
0.808 0.192 0.000
S20-S29 Injuries to the thorax
0.807 0.193 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.807 0.193 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.805 0.195 0.000
I78 Diseases of capillaries
0.801 0.199 0.000
K70-K77 Diseases of liver
0.800 0.200 0.000
Chapter XI Diseases of the digestive system
0.798 0.202 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.798 0.202 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.795 0.205 0.000
J95-J99 Other diseases of the respiratory system
0.795 0.205 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.794 0.206 0.000
E70-E90 Metabolic disorders
0.793 0.207 0.000
Y44 Agents primarily affecting blood constituents
0.792 0.208 0.000
S70-S79 Injuries to the hip and thigh
0.791 0.208 0.000
D75.1 Secondary polycythaemia
0.788 0.212 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.787 0.213 0.000
K70 Alcoholic liver disease
0.787 0.213 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.786 0.214 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.784 0.216 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.783 0.217 0.000
S42 Fracture of shoulder and upper arm
0.782 0.218 0.000
M10 Gout
0.781 0.219 0.000
I67.1 Cerebral aneurysm, nonruptured
0.781 0.219 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.780 0.220 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.779 0.221 0.000
I74.5 Embolism and thrombosis of iliac artery
0.778 0.222 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.777 0.223 0.000
I60 Subarachnoid haemorrhage
0.777 0.223 0.000
M06.9 Rheumatoid arthritis, unspecified
0.777 0.223 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.775 0.225 0.000
M79.5 Residual foreign body in soft tissue
0.774 0.226 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.773 0.227 0.000
S05 Injury of eye and orbit
0.772 0.228 0.000
S06 Intracranial injury
0.772 0.228 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.768 0.232 0.000
M77 Other enthesopathies
0.767 0.233 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.765 0.235 0.000
G30-G32 Other degenerative diseases of the nervous system
0.763 0.237 0.000
H02 Other disorders of eyelid
0.761 0.239 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.760 0.240 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.760 0.240 0.000
T81.9 Unspecified complication of procedure
0.759 0.241 0.000
C16 Malignant neoplasm of stomach
0.759 0.241 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
I67.2 Cerebral atherosclerosis
0.757 0.243 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
S00 Superficial injury of head
0.752 0.248 0.000
T86 Failure and rejection of transplanted organs and tissues
0.751 0.249 0.000
M47 Spondylosis
0.751 0.249 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.751 0.249 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.750 0.250 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.746 0.254 0.000
H53.1 Subjective visual disturbances
0.745 0.255 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.744 0.256 0.000
D68 Other coagulation defects
0.743 0.257 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.743 0.257 0.000
J40-J47 Chronic lower respiratory diseases
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.742 0.257 0.000
J09-J18 Influenza and pneumonia
0.742 0.258 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.741 0.259 0.000
S50-S59 Injuries to the elbow and forearm
0.740 0.260 0.000
C64-C68 Malignant neoplasms of urinary tract
0.739 0.261 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
I26 Pulmonary embolism
0.738 0.262 0.000
Chapter VIII Diseases of the ear and mastoid process
0.737 0.262 0.000
K70.9 Alcoholic liver disease, unspecified
0.737 0.263 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.736 0.263 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.735 0.265 0.000
D80-D89 Certain disorders involving the immune mechanism
0.734 0.266 0.000
Y57 Other and unspecified drugs and medicaments
0.732 0.268 0.000
V80-V89 Other land transport accidents
0.729 0.271 0.000
B35-B49 Mycoses
0.728 0.272 0.000
I62 Other nontraumatic intracranial haemorrhage
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.727 0.273 0.000
D05 Carcinoma in situ of breast
0.727 0.273 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.727 0.273 0.000
H52 Disorders of refraction and accommodation
0.726 0.274 0.000
I72 Other aneurysm
0.725 0.275 0.000
H55-H59 Other disorders of eye and adnexa
0.724 0.276 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.723 0.276 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.723 0.277 0.000
M79.70 Fibromyalgia (Multiple sites)
0.720 0.280 0.000
M48 Other spondylopathies
0.719 0.281 0.000
Y95 Nosocomial condition
0.719 0.281 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
M79.79 Fibromyalgia (Site unspecified)
0.719 0.281 0.000
S01.8 Open wound of other parts of head
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.717 0.283 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.717 0.283 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.717 0.283 0.000
M05 Seropositive rheumatoid arthritis
0.717 0.283 0.000
K70.1 Alcoholic hepatitis
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.715 0.285 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
H30-H36 Disorders of choroid and retina
0.714 0.286 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.714 0.286 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.713 0.286 0.000
J44 Other chronic obstructive pulmonary disease
0.712 0.288 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.712 0.288 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.712 0.288 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.712 0.288 0.000
M07 Psoriatic and enteropathic arthropathies
0.711 0.288 0.000
D72 Other disorders of white blood cells
0.711 0.289 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.711 0.289 0.000
M79.9 Soft tissue disorder, unspecified
0.711 0.289 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.711 0.289 0.000
M79.3 Panniculitis, unspecified
0.711 0.289 0.000
M79.2 Neuralgia and neuritis, unspecified
0.711 0.289 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.711 0.289 0.000
D73 Diseases of spleen
0.710 0.290 0.000
I85 Oesophageal varices
0.710 0.290 0.000
C15 Malignant neoplasm of oesophagus
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
D67 Hereditary factor IX deficiency
0.707 0.293 0.000
D66 Hereditary factor VIII deficiency
0.707 0.293 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.706 0.294 0.000
H54.0 Blindness, both eyes
0.706 0.294 0.000
S80-S89 Injuries to the knee and lower leg
0.706 0.294 0.000
K75 Other inflammatory liver diseases
0.705 0.295 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.705 0.295 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.705 0.295 0.000
I67.5 Moyamoya disease
0.705 0.295 0.000
I67.4 Hypertensive encephalopathy
0.705 0.295 0.000
I67.3 Progressive vascular leukoencephalopathy
0.705 0.295 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.705 0.295 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.298 0.000
Y58 Bacterial vaccines
0.702 0.298 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.702 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.702 0.298 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.702 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.702 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
K65-K67 Diseases of peritoneum
0.702 0.298 0.000
K76 Other diseases of liver
0.702 0.298 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.298 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.701 0.299 0.000
M71 Other bursopathies
0.701 0.299 0.000
D69.9 Haemorrhagic condition, unspecified
0.700 0.299 0.000
D69.8 Other specified haemorrhagic conditions
0.700 0.299 0.000
D69.5 Secondary thrombocytopenia
0.700 0.299 0.000
D69.4 Other primary thrombocytopenia
0.700 0.299 0.000
D69.2 Other nonthrombocytopenic purpura
0.700 0.299 0.000
D69.1 Qualitative platelet defects
0.700 0.299 0.000
D69.0 Allergic purpura
0.700 0.299 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.700 0.300 0.000
R50-R69 General symptoms and signs
0.700 0.300 0.000
D60-D64 Aplastic and other anaemias
0.699 0.301 0.000
H20 Iridocyclitis
0.699 0.301 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.699 0.301 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.697 0.303 0.000
H02.8 Other specified disorders of eyelid
0.697 0.303 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.697 0.303 0.000
D74 Methaemoglobinaemia
0.697 0.303 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.697 0.303 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.697 0.303 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.696 0.304 0.000
D75.2 Essential thrombocytosis
0.695 0.304 0.000
S41 Open wound of shoulder and upper arm
0.695 0.305 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.695 0.305 0.000
D46 Myelodysplastic syndromes
0.695 0.305 0.000
I20-I25 Ischaemic heart diseases
0.695 0.305 0.000
M40-M43 Deforming dorsopathies
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
Y40 Systemic antibiotics
0.692 0.307 0.000
C25 Malignant neoplasm of pancreas
0.692 0.308 0.000
T92 Sequelae of injuries of upper limb
0.691 0.309 0.000
I70 Atherosclerosis
0.690 0.310 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.690 0.310 0.000
G62 Other polyneuropathies
0.690 0.310 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.689 0.310 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.689 0.310 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.689 0.310 0.000
Y52 Agents primarily affecting the cardiovascular system
0.688 0.312 0.000
H53.4 Visual field defects
0.687 0.313 0.000
T66-T78 Other and unspecified effects of external causes
0.686 0.314 0.000
R51 Headache
0.686 0.314 0.000
H01 Other inflammation of eyelid
0.685 0.315 0.000
S90-S99 Injuries to the ankle and foot
0.684 0.316 0.000
H05 Disorders of orbit
0.682 0.317 0.000
G70-G73 Diseases of myoneural junction and muscle
0.680 0.320 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.680 0.320 0.000
S01.0 Open wound of scalp
0.680 0.320 0.000
C20 Malignant neoplasm of rectum
0.680 0.320 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
M75.8 Other shoulder lesions
0.679 0.321 0.000
M75.9 Shoulder lesion, unspecified
0.679 0.321 0.000
M75.2 Bicipital tendinitis
0.679 0.321 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.677 0.322 0.000
M10.9 Gout, unspecified
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
M46 Other inflammatory spondylopathies
0.677 0.323 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.677 0.323 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.676 0.324 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.676 0.324 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.676 0.324 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.676 0.324 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.676 0.324 0.000
I71.0 Dissection of aorta [any part]
0.676 0.324 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.676 0.324 0.000
M79.88 Other specified soft tissue disorders (Other)
0.676 0.324 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.676 0.324 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.676 0.324 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.676 0.324 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.676 0.324 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.676 0.324 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.676 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.676 0.324 0.000
I78.1 Naevus, nonneoplastic
0.674 0.326 0.000
J98 Other respiratory disorders
0.674 0.326 0.000
V20-V29 Motorcycle rider injured in transport accident
0.674 0.326 0.000
H10-H13 Disorders of conjunctiva
0.673 0.327 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.673 0.327 0.000
Y88 Sequelae of surgical and medical care as external cause
0.672 0.328 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.328 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.671 0.329 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.671 0.329 0.000
C16.0 Cardia
0.671 0.329 0.000
D50-D53 Nutritional anaemias
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.670 0.330 0.000
K74 Fibrosis and cirrhosis of liver
0.670 0.330 0.000
A41.8 Other specified septicaemia
0.669 0.331 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.669 0.331 0.000
Y43.9 Primarily systemic agent, unspecified
0.667 0.333 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.667 0.333 0.000
Y43.6 Enzymes, not elsewhere classified
0.667 0.333 0.000
Y43.5 Acidifying and alkalising agents
0.667 0.333 0.000
Y43.4 Immunosuppressive agents
0.667 0.333 0.000
Y43.2 Antineoplastic natural products
0.667 0.333 0.000
Y43.1 Antineoplastic antimetabolites
0.667 0.333 0.000
Y43.0 Antiallergic and antiemetic drugs
0.667 0.333 0.000
E83 Disorders of mineral metabolism
0.667 0.333 0.000
R52 Pain, not elsewhere classified
0.666 0.334 0.000
I87 Other disorders of veins
0.665 0.335 0.000
S02 Fracture of skull and facial bones
0.664 0.336 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.664 0.336 0.000
M14 Arthropathies in other diseases classified elsewhere
0.664 0.336 0.000
M12 Other specific arthropathies
0.664 0.336 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.664 0.336 0.000
M08 Juvenile arthritis
0.664 0.336 0.000
G90-G99 Other disorders of the nervous system
0.664 0.336 0.000
H49 Paralytic strabismus
0.663 0.337 0.000
J60-J70 Lung diseases due to external agents
0.662 0.338 0.000
J81 Pulmonary oedema
0.661 0.339 0.000
S09 Other and unspecified injuries of head
0.661 0.339 0.000
E87.0 Hyperosmolality and hypernatraemia
0.660 0.340 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.660 0.340 0.000
I86 Varicose veins of other sites
0.659 0.341 0.000
S01.7 Multiple open wounds of head
0.659 0.341 0.000
S01.4 Open wound of cheek and temporomandibular area
0.659 0.341 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.658 0.342 0.000
Y44.2 Anticoagulants
0.657 0.343 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.657 0.343 0.000
Y85 Sequelae of transport accidents
0.656 0.344 0.000
I81 Portal vein thrombosis
0.655 0.344 0.000
W00-W19 Falls
0.655 0.345 0.000
I77 Other disorders of arteries and arterioles
0.654 0.346 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.653 0.347 0.000
Q50-Q56 Congenital malformations of genital organs
0.653 0.347 0.000
K83 Other diseases of biliary tract
0.653 0.347 0.000
H54.7 Unspecified visual loss
0.652 0.348 0.000
G83 Other paralytic syndromes
0.651 0.349 0.000
G82 Paraplegia and tetraplegia
0.651 0.349 0.000
G80 Infantile cerebral palsy
0.651 0.349 0.000
S42.1 Fracture of scapula
0.651 0.349 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.651 0.349 0.000
A80-A89 Viral infections of the central nervous system
0.651 0.349 0.000
Chapter XXI Factors influencing health status and contact with health services
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.650 0.349 0.000
D04 Carcinoma in situ of skin
0.649 0.351 0.000
E78.0 Pure hypercholesterolaemia
0.649 0.351 0.000
Y89 Sequelae of other external causes
0.649 0.351 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.649 0.351 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.648 0.352 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.647 0.353 0.000
S40 Superficial injury of shoulder and upper arm
0.647 0.353 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.646 0.354 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.646 0.354 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.646 0.354 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.646 0.354 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.645 0.355 0.000
C50-C50 Malignant neoplasm of breast
0.645 0.355 0.000
H52.1 Myopia
0.644 0.356 0.000
W44 Foreign body entering into or through eye or natural orifice
0.644 0.356 0.000
I82 Other venous embolism and thrombosis
0.643 0.357 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.643 0.357 0.000
M79.6 Pain in limb
0.643 0.357 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.642 0.358 0.000
C67 Malignant neoplasm of bladder
0.642 0.358 0.000
M79.08 Rheumatism, unspecified (Other)
0.642 0.358 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.642 0.358 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.642 0.358 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.642 0.358 0.000
M79.04 Rheumatism, unspecified (Hand)
0.642 0.358 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.642 0.358 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.642 0.358 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.642 0.358 0.000
E88 Other metabolic disorders
0.642 0.358 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
D75.0 Familial erythrocytosis
0.639 0.361 0.000
M79.10 Myalgia (Multiple sites)
0.639 0.361 0.000
I88 Nonspecific lymphadenitis
0.639 0.361 0.000
B99-B99 Other infectious diseases
0.637 0.363 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.637 0.363 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.637 0.363 0.000
B65-B83 Helminthiases
0.637 0.363 0.000
B50-B64 Protozoal diseases
0.637 0.363 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.637 0.363 0.000
B15-B19 Viral hepatitis
0.637 0.363 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.637 0.363 0.000
A75-A79 Rickettsioses
0.637 0.363 0.000
A70-A74 Other diseases caused by chlamydiae
0.637 0.363 0.000
A65-A69 Other spirochaetal diseases
0.637 0.363 0.000
A20-A28 Certain zoonotic bacterial diseases
0.637 0.363 0.000
A15-A19 Tuberculosis
0.637 0.363 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.637 0.363 0.000
S48 Traumatic amputation of shoulder and upper arm
0.637 0.363 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.637 0.363 0.000
S44 Injury of nerves at shoulder and upper arm level
0.637 0.363 0.000
S47 Crushing injury of shoulder and upper arm
0.637 0.363 0.000
S00.0 Superficial injury of scalp
0.637 0.363 0.000
J20-J22 Other acute lower respiratory infections
0.637 0.363 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.637 0.363 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.636 0.364 0.000
S12 Fracture of neck
0.635 0.365 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.635 0.365 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.635 0.365 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.635 0.365 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.635 0.365 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.635 0.365 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.635 0.365 0.000
I65.2 Occlusion and stenosis of carotid artery
0.635 0.365 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.635 0.365 0.000
M49 Spondylopathies in diseases classified elsewhere
0.634 0.366 0.000
S32 Fracture of lumbar spine and pelvis
0.634 0.366 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.633 0.366 0.000
Q80-Q89 Other congenital malformations
0.633 0.366 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.633 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.633 0.366 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.633 0.366 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.633 0.366 0.000
Q00-Q07 Congenital malformations of the nervous system
0.633 0.366 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.633 0.367 0.000
H53.2 Diplopia
0.633 0.367 0.000
S05.8 Other injuries of eye and orbit
0.633 0.367 0.000
H00 Hordeolum and chalazion
0.632 0.368 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.632 0.368 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.632 0.368 0.000
K65 Peritonitis
0.631 0.369 0.000
G81.1 Spastic hemiplegia
0.631 0.369 0.000
G81.0 Flaccid hemiplegia
0.631 0.369 0.000
E10-E14 Diabetes mellitus
0.630 0.370 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.629 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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