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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75323949
log Bayes Factor = 6.24792
Chromosome 8   position 69,545,445  (GRCh37) Explore rs75323949 on Ensembl!
Variant rs75323949 is part of Cluster X0053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I50.1 Left ventricular failure
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
I42 Cardiomyopathy
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Z45 Adjustment and management of implanted device
0.991 0.009 0.000
A30-A49 Other bacterial diseases
0.990 0.010 0.000
A41 Other septicaemia
0.989 0.011 0.000
A41.9 Septicaemia, unspecified
0.979 0.021 0.000
I50.0 Congestive heart failure
0.971 0.029 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.965 0.035 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
I42.9 Cardiomyopathy, unspecified
0.958 0.042 0.000
Z45.2 Adjustment and management of vascular access device
0.956 0.044 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.949 0.051 0.000
D80-D89 Certain disorders involving the immune mechanism
0.947 0.053 0.000
Z45.8 Adjustment and management of other implanted devices
0.941 0.059 0.000
I05-I09 Chronic rheumatic heart diseases
0.935 0.065 0.000
I42.0 Dilated cardiomyopathy
0.935 0.065 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.933 0.067 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.932 0.068 0.000
S80-S89 Injuries to the knee and lower leg
0.924 0.076 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.920 0.080 0.000
Z51 Other medical care
0.918 0.082 0.000
D70 Agranulocytosis
0.912 0.088 0.000
Z53.0 Procedure not carried out because of contraindication
0.903 0.097 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.903 0.097 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.901 0.099 0.000
S20-S29 Injuries to the thorax
0.898 0.102 0.000
B25-B34 Other viral diseases
0.896 0.103 0.000
Z29 Need for other prophylactic measures
0.894 0.106 0.000
Z41 Procedures for purposes other than remedying health state
0.892 0.108 0.000
Z47 Other orthopaedic follow-up care
0.889 0.111 0.000
S40-S49 Injuries to the shoulder and upper arm
0.886 0.114 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.883 0.117 0.000
I35 Nonrheumatic aortic valve disorders
0.882 0.118 0.000
A41.8 Other specified septicaemia
0.882 0.118 0.000
E70-E90 Metabolic disorders
0.882 0.118 0.000
B15-B19 Viral hepatitis
0.882 0.118 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.879 0.121 0.000
Z52 Donors of organs and tissues
0.879 0.121 0.000
E87.6 Hypokalaemia
0.869 0.131 0.000
I31 Other diseases of pericardium
0.866 0.134 0.000
T66-T78 Other and unspecified effects of external causes
0.864 0.136 0.000
E87.5 Hyperkalaemia
0.862 0.138 0.000
I07 Rheumatic tricuspid valve diseases
0.861 0.139 0.000
Z29.2 Other prophylactic chemotherapy
0.848 0.152 0.000
D73 Diseases of spleen
0.844 0.156 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.844 0.156 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.839 0.161 0.000
D60-D64 Aplastic and other anaemias
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.832 0.168 0.000
S82 Fracture of lower leg, including ankle
0.831 0.169 0.000
X60-X84 Intentional self-harm
0.830 0.170 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.829 0.171 0.000
S90-S99 Injuries to the ankle and foot
0.828 0.172 0.000
S32 Fracture of lumbar spine and pelvis
0.828 0.172 0.000
Z51.1 Chemotherapy session for neoplasm
0.826 0.174 0.000
D80 Immunodeficiency with predominantly antibody defects
0.824 0.176 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.821 0.179 0.000
I95 Hypotension
0.816 0.184 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.816 0.184 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.815 0.185 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.814 0.186 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.814 0.186 0.000
Z53.9 Procedure not carried out, unspecified reason
0.812 0.188 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.811 0.189 0.000
I07.1 Tricuspid insufficiency
0.808 0.192 0.000
I08 Multiple valve diseases
0.803 0.197 0.000
S80 Superficial injury of lower leg
0.802 0.198 0.000
Z51.3 Blood transfusion without reported diagnosis
0.802 0.198 0.000
D86 Sarcoidosis
0.800 0.200 0.000
T23 Burn and corrosion of wrist and hand
0.798 0.202 0.000
Z52.4 Kidney donor
0.793 0.207 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.792 0.208 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.791 0.209 0.000
B34 Viral infection of unspecified site
0.790 0.210 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.787 0.213 0.000
I33 Acute and subacute endocarditis
0.787 0.213 0.000
S82.1 Fracture of upper end of tibia
0.785 0.215 0.000
Y43 Primarily systemic agents
0.784 0.216 0.000
W20-W49 Exposure to inanimate mechanical forces
0.783 0.217 0.000
I35.9 Aortic valve disorder, unspecified
0.779 0.221 0.000
Z46 Fitting and adjustment of other devices
0.779 0.221 0.000
D55-D59 Haemolytic anaemias
0.777 0.223 0.000
B99-B99 Other infectious diseases
0.777 0.223 0.000
A48 Other bacterial diseases, not elsewhere classified
0.774 0.226 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.774 0.226 0.000
I42.2 Other hypertrophic cardiomyopathy
0.773 0.227 0.000
I35.0 Aortic (valve) stenosis
0.773 0.227 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.771 0.229 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.766 0.234 0.000
Y45.0 Opioids and related analgesics
0.763 0.237 0.000
E20-E35 Disorders of other endocrine glands
0.763 0.237 0.000
T78 Adverse effects, not elsewhere classified
0.762 0.238 0.000
Z45.1 Adjustment and management of infusion pump
0.760 0.240 0.000
Z22 Carrier of infectious disease
0.758 0.242 0.000
S81 Open wound of lower leg
0.757 0.243 0.000
I51 Complications and ill-defined descriptions of heart disease
0.755 0.245 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.755 0.245 0.000
S82.10 Fracture of upper end of tibia (closed)
0.752 0.248 0.000
S10-S19 Injuries to the neck
0.749 0.250 0.000
B35-B49 Mycoses
0.747 0.253 0.000
S42 Fracture of shoulder and upper arm
0.746 0.254 0.000
B18 Chronic viral hepatitis
0.744 0.256 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.741 0.259 0.000
A40 Streptococcal septicaemia
0.739 0.261 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.736 0.264 0.000
S29 Other and unspecified injuries of thorax
0.735 0.265 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.735 0.265 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.734 0.266 0.000
W50-W64 Exposure to animate mechanical forces
0.734 0.266 0.000
I42.8 Other cardiomyopathies
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.266 0.000
E50-E64 Other nutritional deficiencies
0.732 0.268 0.000
B25 Cytomegaloviral disease
0.730 0.270 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.729 0.271 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.727 0.273 0.000
S22.3 Fracture of rib
0.727 0.273 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.725 0.274 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.724 0.276 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.724 0.276 0.000
Chapter VII Diseases of the eye and adnexa
0.724 0.276 0.000
I38 Endocarditis, valve unspecified
0.721 0.279 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.721 0.279 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.281 0.000
S32.0 Fracture of lumbar vertebra
0.718 0.281 0.000
I31.3 Pericardial effusion (noninflammatory)
0.718 0.282 0.000
Z48 Other surgical follow-up care
0.718 0.282 0.000
S82.0 Fracture of patella
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.715 0.285 0.000
S31 Open wound of abdomen, lower back and pelvis
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
I99 Other and unspecified disorders of circulatory system
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
I51.7 Cardiomegaly
0.713 0.287 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.713 0.287 0.000
I42.6 Alcoholic cardiomyopathy
0.713 0.287 0.000
I42.5 Other restrictive cardiomyopathy
0.713 0.287 0.000
I42.4 Endocardial fibroelastosis
0.713 0.287 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.713 0.287 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
I46 Cardiac arrest
0.712 0.288 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.710 0.289 0.000
Z45.3 Adjustment and management of implanted hearing device
0.710 0.289 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.710 0.290 0.000
I49 Other cardiac arrhythmias
0.710 0.290 0.000
A44 Bartonellosis
0.710 0.290 0.000
A43 Nocardiosis
0.710 0.290 0.000
A42 Actinomycosis
0.710 0.290 0.000
A39 Meningococcal infection
0.710 0.290 0.000
A37 Whooping cough
0.710 0.290 0.000
A36 Diphtheria
0.710 0.290 0.000
A32 Listeriosis
0.710 0.290 0.000
A31 Infection due to other mycobacteria
0.710 0.290 0.000
A30 Leprosy [Hansen's disease]
0.710 0.290 0.000
A38 Scarlet fever
0.710 0.290 0.000
A35 Other tetanus
0.710 0.290 0.000
A34 Obstetrical tetanus
0.710 0.290 0.000
A33 Tetanus neonatorum
0.710 0.290 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.710 0.290 0.000
A41.4 Septicaemia due to anaerobes
0.709 0.291 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
I31.9 Disease of pericardium, unspecified
0.706 0.294 0.000
I30 Acute pericarditis
0.704 0.296 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.703 0.296 0.000
I95.9 Hypotension, unspecified
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.701 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.298 0.000
D73.8 Other diseases of spleen
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.700 0.300 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.699 0.301 0.000
E87.3 Alkalosis
0.699 0.301 0.000
I95.0 Idiopathic hypotension
0.698 0.302 0.000
I10-I15 Hypertensive diseases
0.697 0.303 0.000
D73.0 Hyposplenism
0.696 0.304 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.695 0.305 0.000
D69 Purpura and other haemorrhagic conditions
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
S22.0 Fracture of thoracic vertebra
0.694 0.306 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.693 0.306 0.000
Z28 Immunisation not carried out
0.692 0.308 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.692 0.308 0.000
Z26 Need for immunisation against other single infectious diseases
0.692 0.308 0.000
Z25 Need for immunisation against other single viral diseases
0.692 0.308 0.000
Z24 Need for immunisation against certain single viral diseases
0.692 0.308 0.000
Z23 Need for immunisation against single bacterial diseases
0.692 0.308 0.000
Z20 Contact with and exposure to communicable diseases
0.692 0.308 0.000
B17 Other acute viral hepatitis
0.691 0.309 0.000
B16 Acute hepatitis B
0.691 0.309 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.690 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.309 0.000
Chapter II Neoplasms
0.691 0.309 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
T21 Burn and corrosion of trunk
0.687 0.312 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.687 0.313 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.686 0.314 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.684 0.315 0.000
E10-E14 Diabetes mellitus
0.684 0.316 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.683 0.317 0.000
B44 Aspergillosis
0.682 0.318 0.000
S92 Fracture of foot, except ankle
0.682 0.318 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.681 0.319 0.000
D74 Methaemoglobinaemia
0.681 0.319 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.681 0.319 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.681 0.319 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.681 0.319 0.000
B34.9 Viral infection, unspecified
0.681 0.319 0.000
D86.9 Sarcoidosis, unspecified
0.680 0.320 0.000
D84 Other immunodeficiencies
0.679 0.321 0.000
D83 Common variable immunodeficiency
0.679 0.321 0.000
D82 Immunodeficiency associated with other major defects
0.679 0.321 0.000
D81 Combined immunodeficiencies
0.679 0.321 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.679 0.321 0.000
S32.5 Fracture of pubis
0.677 0.323 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.676 0.323 0.000
Z54 Convalescence
0.675 0.325 0.000
Z29.1 Prophylactic immunotherapy
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
Z51.2 Other chemotherapy
0.672 0.328 0.000
B65-B83 Helminthiases
0.671 0.328 0.000
D61 Other aplastic anaemias
0.671 0.329 0.000
Y43.3 Other antineoplastic drugs
0.671 0.329 0.000
I09 Other rheumatic heart diseases
0.671 0.329 0.000
I06 Rheumatic aortic valve diseases
0.671 0.329 0.000
X58 Exposure to other specified factors
0.670 0.330 0.000
Z51.8 Other specified medical care
0.670 0.330 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.330 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.669 0.331 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
X62.9 Unspecified place
0.667 0.333 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
S42.4 Fracture of lower end of humerus
0.666 0.334 0.000
X20-X29 Contact with venomous animals and plants
0.665 0.334 0.000
Z22.5 Carrier of viral hepatitis
0.662 0.337 0.000
S88 Traumatic amputation of lower leg
0.662 0.337 0.000
S87 Crushing injury of lower leg
0.662 0.337 0.000
S86 Injury of muscle and tendon at lower leg level
0.662 0.337 0.000
S85 Injury of blood vessels at lower leg level
0.662 0.337 0.000
S84 Injury of nerves at lower leg level
0.662 0.337 0.000
S91 Open wound of ankle and foot
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
S22.30 Fracture of rib (closed)
0.660 0.340 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.659 0.341 0.000
Z51.9 Medical care, unspecified
0.658 0.342 0.000
Z51.6 Desensitisation to allergens
0.658 0.342 0.000
E74 Other disorders of carbohydrate metabolism
0.658 0.342 0.000
Z48.0 Attention to surgical dressings and sutures
0.658 0.342 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.658 0.342 0.000
Z43 Attention to artificial openings
0.657 0.342 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.657 0.343 0.000
T36 Poisoning by systemic antibiotics
0.656 0.344 0.000
T78.4 Allergy, unspecified
0.656 0.344 0.000
X50-X57 Overexertion, travel and privation
0.655 0.345 0.000
H46 Optic neuritis
0.655 0.345 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.654 0.346 0.000
Z29.0 Isolation
0.654 0.346 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.653 0.347 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.650 0.350 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
A46 Erysipelas
0.649 0.350 0.000
S40 Superficial injury of shoulder and upper arm
0.649 0.351 0.000
E00-E07 Disorders of thyroid gland
0.649 0.351 0.000
S43.0 Dislocation of shoulder joint
0.649 0.351 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.649 0.351 0.000
W22 Striking against or struck by other objects
0.648 0.352 0.000
T25 Burn and corrosion of ankle and foot
0.647 0.352 0.000
T20 Burn and corrosion of head and neck
0.647 0.352 0.000
I35.8 Other aortic valve disorders
0.647 0.353 0.000
Y59 Other and unspecified vaccines and biological substances
0.647 0.353 0.000
Y58 Bacterial vaccines
0.647 0.353 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.647 0.353 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.647 0.353 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.647 0.353 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.646 0.354 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.646 0.354 0.000
S36 Injury of intra-abdominal organs
0.646 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.646 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.646 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.646 0.354 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.645 0.355 0.000
I49.3 Ventricular premature depolarisation
0.645 0.355 0.000
S50-S59 Injuries to the elbow and forearm
0.644 0.356 0.000
X59 Exposure to unspecified factor
0.644 0.356 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.644 0.356 0.000
S27 Injury of other and unspecified intrathoracic organs
0.644 0.356 0.000
S26 Injury of heart
0.644 0.356 0.000
S25 Injury of blood vessels of thorax
0.644 0.356 0.000
S24 Injury of nerves and spinal cord at thorax level
0.644 0.356 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.644 0.356 0.000
S21 Open wound of thorax
0.644 0.356 0.000
B33 Other viral diseases, not elsewhere classified
0.643 0.357 0.000
B30 Viral conjunctivitis
0.643 0.357 0.000
B27 Infectious mononucleosis
0.643 0.357 0.000
B26 Mumps
0.643 0.357 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.642 0.358 0.000
Z29.9 Prophylactic measure, unspecified
0.641 0.359 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.641 0.359 0.000
C92 Myeloid leukaemia
0.641 0.359 0.000
D72 Other disorders of white blood cells
0.640 0.360 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.640 0.360 0.000
D73.5 Infarction of spleen
0.640 0.360 0.000
S81.9 Open wound of lower leg, part unspecified
0.640 0.360 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.639 0.360 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.639 0.360 0.000
Z41.3 Ear piercing
0.639 0.360 0.000
Z41.2 Routine and ritual circumcision
0.639 0.360 0.000
Z41.0 Hair transplant
0.639 0.360 0.000
S41 Open wound of shoulder and upper arm
0.639 0.361 0.000
S89 Other and unspecified injuries of lower leg
0.639 0.361 0.000
Z40 Prophylactic surgery
0.638 0.362 0.000
I95.1 Orthostatic hypotension
0.638 0.362 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.638 0.362 0.000
T68 Hypothermia
0.638 0.362 0.000
S82.00 Fracture of patella (closed)
0.637 0.363 0.000
V20-V29 Motorcycle rider injured in transport accident
0.635 0.365 0.000
S48 Traumatic amputation of shoulder and upper arm
0.635 0.365 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.635 0.365 0.000
S44 Injury of nerves at shoulder and upper arm level
0.635 0.365 0.000
S47 Crushing injury of shoulder and upper arm
0.635 0.365 0.000
I33.0 Acute and subacute infective endocarditis
0.635 0.365 0.000
D63.0 Anaemia in neoplastic disease
0.635 0.365 0.000
E85 Amyloidosis
0.634 0.366 0.000
E87.4 Mixed disorder of acid-base balance
0.633 0.367 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.367 0.000
E84 Cystic fibrosis
0.632 0.367 0.000
E79 Disorders of purine and pyrimidine metabolism
0.632 0.367 0.000
E77 Disorders of glycoprotein metabolism
0.632 0.367 0.000
E76 Disorders of glycosaminoglycan metabolism
0.632 0.367 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.632 0.367 0.000
E72 Other disorders of amino-acid metabolism
0.632 0.367 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.632 0.367 0.000
E70 Disorders of aromatic amino-acid metabolism
0.632 0.367 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.632 0.367 0.000
B19 Unspecified viral hepatitis
0.632 0.368 0.000
B15 Acute hepatitis A
0.632 0.368 0.000
B34.8 Other viral infections of unspecified site
0.632 0.368 0.000
S99 Other and unspecified injuries of ankle and foot
0.632 0.368 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.630 0.369 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.630 0.370 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.630 0.370 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.630 0.370 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.630 0.370 0.000
S82.2 Fracture of shaft of tibia
0.630 0.370 0.000
Z52.9 Donor of unspecified organ or tissue
0.630 0.370 0.000
Z52.8 Donor of other organs and tissues
0.630 0.370 0.000
Z52.7 Heart donor
0.630 0.370 0.000
Z52.6 Liver donor
0.630 0.370 0.000
Z52.5 Cornea donor
0.630 0.370 0.000
Z52.3 Bone marrow donor
0.630 0.370 0.000
Z52.2 Bone donor
0.630 0.370 0.000
Z52.1 Skin donor
0.630 0.370 0.000
Z52.0 Blood donor
0.630 0.370 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.629 0.371 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.627 0.373 0.000
Y45.8 Other analgesics and antipyretics
0.625 0.374 0.000
T23.2 Burn of second degree of wrist and hand
0.625 0.375 0.000
C92.0 Acute myeloid leukaemia
0.625 0.375 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.624 0.376 0.000
S82.6 Fracture of lateral malleolus
0.623 0.377 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.622 0.378 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.622 0.378 0.000
Q50-Q56 Congenital malformations of genital organs
0.621 0.378 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.621 0.379 0.000
I31.8 Other specified diseases of pericardium
0.621 0.379 0.000
I31.2 Haemopericardium, not elsewhere classified
0.621 0.379 0.000
I31.1 Chronic constrictive pericarditis
0.621 0.379 0.000
I31.0 Chronic adhesive pericarditis
0.621 0.379 0.000
Q80-Q89 Other congenital malformations
0.621 0.379 0.000
B99 Other and unspecified infectious diseases
0.620 0.379 0.000
T75 Effects of other external causes
0.620 0.380 0.000
T74 Maltreatment syndromes
0.620 0.380 0.000
T73 Effects of other deprivation
0.620 0.380 0.000
T70 Effects of air pressure and water pressure
0.620 0.380 0.000
T69 Other effects of reduced temperature
0.620 0.380 0.000
T67 Effects of heat and light
0.620 0.380 0.000
T71 Asphyxiation
0.620 0.380 0.000
T66 Unspecified effects of radiation
0.620 0.380 0.000
A48.1 Legionnaires' disease
0.619 0.381 0.000
S29.9 Unspecified injury of thorax
0.619 0.381 0.000
Y43.4 Immunosuppressive agents
0.619 0.381 0.000
S80.9 Superficial injury of lower leg, unspecified
0.618 0.382 0.000
I07.9 Tricuspid valve disease, unspecified
0.618 0.382 0.000
I07.8 Other tricuspid valve diseases
0.618 0.382 0.000
I07.2 Tricuspid stenosis with insufficiency
0.618 0.382 0.000
I07.0 Tricuspid stenosis
0.618 0.382 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.616 0.384 0.000
E73 Lactose intolerance
0.615 0.385 0.000
S71 Open wound of hip and thigh
0.614 0.386 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.614 0.386 0.000
D86.0 Sarcoidosis of lung
0.614 0.386 0.000
H43-H45 Disorders of vitreous body and globe
0.613 0.387 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.613 0.387 0.000
Y95 Nosocomial condition
0.612 0.388 0.000
B44.1 Other pulmonary aspergillosis
0.611 0.389 0.000
B25.9 Cytomegaloviral disease, unspecified
0.611 0.389 0.000
S22.5 Flail chest
0.610 0.390 0.000
Z04 Examination and observation for other reasons
0.609 0.391 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.608 0.392 0.000
S42.40 Fracture of lower end of humerus (closed)
0.608 0.392 0.000
I05 Rheumatic mitral valve diseases
0.608 0.392 0.000
X41.9 Unspecified place
0.607 0.393 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.607 0.393 0.000
X78 Intentional self-harm by sharp object
0.606 0.394 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.606 0.394 0.000
D73.9 Disease of spleen, unspecified
0.605 0.395 0.000
D73.4 Cyst of spleen
0.605 0.395 0.000
D73.3 Abscess of spleen
0.605 0.395 0.000
D73.2 Chronic congestive splenomegaly
0.605 0.395 0.000
D73.1 Hypersplenism
0.605 0.395 0.000
S32.4 Fracture of acetabulum
0.604 0.395 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.604 0.396 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.604 0.396 0.000
E34 Other endocrine disorders
0.603 0.397 0.000
T91 Sequelae of injuries of neck and trunk
0.602 0.398 0.000
Q00-Q07 Congenital malformations of the nervous system
0.602 0.398 0.000
Y57 Other and unspecified drugs and medicaments
0.601 0.399 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.600 0.399 0.000
E24 Cushing's syndrome
0.600 0.400 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.600 0.400 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.599 0.401 0.000
S22.1 Multiple fractures of thoracic spine
0.599 0.401 0.000
C45 Mesothelioma
0.599 0.401 0.000
D59 Acquired haemolytic anaemia
0.598 0.401 0.000
E28 Ovarian dysfunction
0.597 0.403 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.597 0.403 0.000
Q35-Q37 Cleft lip and cleft palate
0.597 0.403 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.597 0.403 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.597 0.403 0.000
I50.9 Heart failure, unspecified
0.596 0.404 0.000
S82.9 Fracture of lower leg, part unspecified
0.596 0.404 0.000
S82.7 Multiple fractures of lower leg
0.596 0.404 0.000
X84 Intentional self-harm by unspecified means
0.595 0.405 0.000
X83 Intentional self-harm by other specified means
0.595 0.405 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.595 0.405 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.595 0.405 0.000
X80 Intentional self-harm by jumping from a high place
0.595 0.405 0.000
X79 Intentional self-harm by blunt object
0.595 0.405 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.595 0.405 0.000
X76 Intentional self-harm by smoke, fire and flames
0.595 0.405 0.000
X75 Intentional self-harm by explosive material
0.595 0.405 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.595 0.405 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.595 0.405 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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