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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75417855
log Bayes Factor = 21.8115
Chromosome 8   position 8,966,147  (GRCh37) Explore rs75417855 on Ensembl!
Variant rs75417855 is part of Cluster X0176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
T81 Complications of procedures, not elsewhere classified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
N81 Female genital prolapse
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.992 0.008 0.000
Chapter II Neoplasms
0.990 0.010 0.000
M15-M19 Arthrosis
0.989 0.011 0.000
M16 Coxarthrosis [arthrosis of hip]
0.986 0.014 0.000
N18 Chronic renal failure
0.985 0.015 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.985 0.015 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.983 0.017 0.000
M70-M79 Other soft tissue disorders
0.982 0.018 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.977 0.023 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.976 0.024 0.000
M16.9 Coxarthrosis, unspecified
0.970 0.030 0.000
C50-C50 Malignant neoplasm of breast
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
N18.9 Chronic renal failure, unspecified
0.964 0.036 0.000
D70 Agranulocytosis
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.956 0.044 0.000
C50 Malignant neoplasm of breast
0.956 0.044 0.000
N17 Acute renal failure
0.953 0.047 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.952 0.048 0.000
O60-O75 Complications of labour and delivery
0.952 0.048 0.000
E70-E90 Metabolic disorders
0.952 0.048 0.000
J09-J18 Influenza and pneumonia
0.951 0.049 0.000
M16.0 Primary coxarthrosis, bilateral
0.949 0.051 0.000
N19 Unspecified renal failure
0.947 0.053 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.946 0.054 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
Y83.4 Other reconstructive surgery
0.943 0.057 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.939 0.061 0.000
M05-M14 Inflammatory polyarthropathies
0.937 0.063 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.936 0.064 0.000
C50.9 Breast, unspecified
0.934 0.066 0.000
S80-S89 Injuries to the knee and lower leg
0.933 0.067 0.000
M20-M25 Other joint disorders
0.932 0.068 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.930 0.070 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.930 0.070 0.000
N30-N39 Other diseases of urinary system
0.928 0.072 0.000
Chapter VII Diseases of the eye and adnexa
0.926 0.074 0.000
J95-J99 Other diseases of the respiratory system
0.926 0.074 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.921 0.079 0.000
Z50 Care involving use of rehabilitation procedures
0.920 0.080 0.000
N17.9 Acute renal failure, unspecified
0.920 0.080 0.000
D73 Diseases of spleen
0.920 0.080 0.000
J90-J94 Other diseases of pleura
0.916 0.084 0.000
O70 Perineal laceration during delivery
0.916 0.084 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.915 0.085 0.000
J18 Pneumonia, organism unspecified
0.913 0.087 0.000
M75 Shoulder lesions
0.912 0.088 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.909 0.091 0.000
N81.1 Cystocele
0.904 0.096 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
Z51 Other medical care
0.902 0.098 0.000
M86-M90 Other osteopathies
0.901 0.098 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.901 0.099 0.000
Chapter VI Diseases of the nervous system
0.897 0.103 0.000
N81.4 Uterovaginal prolapse, unspecified
0.893 0.107 0.000
N32 Other disorders of bladder
0.893 0.107 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.891 0.109 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.889 0.111 0.000
M54 Dorsalgia
0.888 0.112 0.000
N89 Other noninflammatory disorders of vagina
0.885 0.115 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.884 0.116 0.000
J98 Other respiratory disorders
0.882 0.118 0.000
O70.0 First degree perineal laceration during delivery
0.882 0.118 0.000
E87.2 Acidosis
0.881 0.119 0.000
N32.8 Other specified disorders of bladder
0.881 0.119 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.880 0.120 0.000
N81.6 Rectocele
0.878 0.122 0.000
M35 Other systemic involvement of connective tissue
0.877 0.123 0.000
O00-O08 Pregnancy with abortive outcome
0.870 0.130 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.868 0.132 0.000
N81.2 Incomplete uterovaginal prolapse
0.867 0.133 0.000
M45-M49 Spondylopathies
0.864 0.136 0.000
Y83.3 Surgical operation with formation of external stoma
0.862 0.138 0.000
M13 Other arthritis
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.860 0.140 0.000
E83 Disorders of mineral metabolism
0.858 0.142 0.000
S80 Superficial injury of lower leg
0.856 0.144 0.000
N81.3 Complete uterovaginal prolapse
0.856 0.144 0.000
E87.7 Fluid overload
0.855 0.145 0.000
E87.5 Hyperkalaemia
0.852 0.148 0.000
D73.0 Hyposplenism
0.851 0.149 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.850 0.150 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.849 0.151 0.000
N86 Erosion and ectropion of cervix uteri
0.848 0.152 0.000
Y83.6 Removal of other organ (partial) (total)
0.847 0.153 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.845 0.155 0.000
J90 Pleural effusion, not elsewhere classified
0.845 0.155 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.843 0.157 0.000
J00-J06 Acute upper respiratory infections
0.840 0.160 0.000
V10-V19 Pedal cyclist injured in transport accident
0.839 0.161 0.000
O04 Medical abortion
0.837 0.163 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.836 0.164 0.000
J18.1 Lobar pneumonia, unspecified
0.836 0.164 0.000
Z51.1 Chemotherapy session for neoplasm
0.833 0.167 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.831 0.169 0.000
N18.0 End-stage renal disease
0.829 0.171 0.000
Z96 Presence of other functional implants
0.828 0.172 0.000
M51 Other intervertebral disk disorders
0.827 0.173 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.827 0.173 0.000
Z51.0 Radiotherapy session
0.825 0.175 0.000
N94.1 Dyspareunia
0.823 0.177 0.000
E87.0 Hyperosmolality and hypernatraemia
0.822 0.178 0.000
H40-H42 Glaucoma
0.822 0.178 0.000
B95-B98 Bacterial, viral and other infectious agents
0.822 0.178 0.000
M54.5 Low back pain
0.820 0.180 0.000
C50.1 Central portion of breast
0.819 0.181 0.000
H30-H36 Disorders of choroid and retina
0.817 0.183 0.000
M10 Gout
0.813 0.186 0.000
O04.9 Complete or unspecified, without complication
0.813 0.187 0.000
O62 Abnormalities of forces of labour
0.812 0.188 0.000
T85.2 Mechanical complication of intraocular lens
0.812 0.188 0.000
Z50.1 Other physical therapy
0.811 0.189 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.810 0.190 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.809 0.190 0.000
M75.3 Calcific tendinitis of shoulder
0.808 0.192 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.807 0.193 0.000
M13.9 Arthritis, unspecified
0.806 0.194 0.000
A30-A49 Other bacterial diseases
0.806 0.194 0.000
M40-M43 Deforming dorsopathies
0.804 0.196 0.000
M35.3 Polymyalgia rheumatica
0.804 0.196 0.000
Z93 Artificial opening status
0.804 0.196 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.802 0.198 0.000
M21 Other acquired deformities of limbs
0.801 0.199 0.000
C50.3 Lower-inner quadrant of breast
0.801 0.199 0.000
Z75 Problems related to medical facilities and other health care
0.800 0.200 0.000
Z72 Problems related to lifestyle
0.797 0.203 0.000
D80-D89 Certain disorders involving the immune mechanism
0.796 0.204 0.000
J18.9 Pneumonia, unspecified
0.796 0.204 0.000
Z96.1 Presence of intraocular lens
0.795 0.205 0.000
T66-T78 Other and unspecified effects of external causes
0.795 0.205 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.205 0.000
Z93.3 Colostomy status
0.794 0.206 0.000
T87 Complications peculiar to reattachment and amputation
0.793 0.207 0.000
Z35 Supervision of high-risk pregnancy
0.793 0.207 0.000
Chapter IX Diseases of the circulatory system
0.790 0.210 0.000
M67 Other disorders of synovium and tendon
0.787 0.213 0.000
J98.1 Pulmonary collapse
0.787 0.213 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.787 0.213 0.000
G40-G47 Episodic and paroxysmal disorders
0.779 0.221 0.000
M79.8 Other specified soft tissue disorders
0.778 0.222 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.776 0.224 0.000
O70.9 Perineal laceration during delivery, unspecified
0.775 0.225 0.000
D75 Other diseases of blood and blood-forming organs
0.775 0.225 0.000
G30-G32 Other degenerative diseases of the nervous system
0.775 0.225 0.000
M18 Arthrosis of first carpometacarpal joint
0.774 0.225 0.000
C51-C58 Malignant neoplasms of female genital organs
0.773 0.227 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.773 0.227 0.000
D45 Polycythaemia vera
0.773 0.227 0.000
S81 Open wound of lower leg
0.772 0.228 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.769 0.231 0.000
H25-H28 Disorders of lens
0.769 0.231 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.768 0.232 0.000
N34 Urethritis and urethral syndrome
0.767 0.232 0.000
Z72.0 Tobacco use
0.767 0.233 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
Z51.3 Blood transfusion without reported diagnosis
0.766 0.234 0.000
M75.2 Bicipital tendinitis
0.765 0.235 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.762 0.238 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.762 0.238 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.762 0.238 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.759 0.241 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
Z37 Outcome of delivery
0.759 0.241 0.000
M89 Other disorders of bone
0.758 0.242 0.000
O66 Other obstructed labour
0.758 0.242 0.000
M50 Cervical disk disorders
0.756 0.244 0.000
M47 Spondylosis
0.756 0.244 0.000
N83.2 Other and unspecified ovarian cysts
0.756 0.244 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.756 0.244 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.755 0.245 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.755 0.245 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.754 0.246 0.000
J98.4 Other disorders of lung
0.754 0.246 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.754 0.246 0.000
N18.5 Chronic kidney disease, stage 5
0.754 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.753 0.246 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.753 0.247 0.000
M54.59 Low back pain (Site unspecified)
0.753 0.247 0.000
M16.3 Other dysplastic coxarthrosis
0.752 0.248 0.000
E88 Other metabolic disorders
0.751 0.249 0.000
M77 Other enthesopathies
0.750 0.250 0.000
D46 Myelodysplastic syndromes
0.749 0.251 0.000
H40 Glaucoma
0.748 0.252 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.747 0.253 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.747 0.253 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.747 0.253 0.000
N81.8 Other female genital prolapse
0.746 0.253 0.000
Z50.8 Care involving use of rehabilitation procedures
0.746 0.254 0.000
C85.1 B-cell lymphoma, unspecified
0.746 0.254 0.000
J84 Other interstitial pulmonary diseases
0.745 0.255 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.745 0.255 0.000
Y83.8 Other surgical procedures
0.745 0.255 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.744 0.256 0.000
M35.0 Sicca syndrome [Sjogren]
0.743 0.257 0.000
D73.5 Infarction of spleen
0.743 0.257 0.000
J94 Other pleural conditions
0.742 0.258 0.000
N39 Other disorders of urinary system
0.742 0.258 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.741 0.259 0.000
M25 Other joint disorders, not elsewhere classified
0.740 0.260 0.000
N00-N08 Glomerular diseases
0.739 0.261 0.000
Y83.9 Surgical procedure, unspecified
0.738 0.262 0.000
Z36 Antenatal screening
0.737 0.263 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.736 0.263 0.000
N73 Other female pelvic inflammatory diseases
0.736 0.264 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.736 0.264 0.000
S10-S19 Injuries to the neck
0.736 0.264 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.735 0.264 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.735 0.265 0.000
O70.2 Third degree perineal laceration during delivery
0.735 0.265 0.000
J40-J47 Chronic lower respiratory diseases
0.735 0.265 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.734 0.266 0.000
N32.3 Diverticulum of bladder
0.733 0.267 0.000
D00-D09 In situ neoplasms
0.733 0.267 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.732 0.268 0.000
Y95 Nosocomial condition
0.732 0.268 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.732 0.268 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.731 0.269 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.731 0.269 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.730 0.269 0.000
O80-O84 Delivery
0.729 0.270 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.729 0.271 0.000
M72 Fibroblastic disorders
0.729 0.271 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.729 0.271 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.728 0.272 0.000
M88 Paget's disease of bone [osteitis deformans]
0.728 0.272 0.000
M75.5 Bursitis of shoulder
0.728 0.272 0.000
Z96.0 Presence of urogenital implants
0.728 0.272 0.000
M53 Other dorsopathies, not elsewhere classified
0.727 0.273 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.727 0.273 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.725 0.275 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.725 0.275 0.000
Z49 Care involving dialysis
0.725 0.275 0.000
M10.9 Gout, unspecified
0.725 0.275 0.000
H10-H13 Disorders of conjunctiva
0.724 0.276 0.000
N84 Polyp of female genital tract
0.724 0.276 0.000
E83.1 Disorders of iron metabolism
0.724 0.276 0.000
Z31 Procreative management
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.722 0.277 0.000
B35-B49 Mycoses
0.722 0.278 0.000
N80 Endometriosis
0.722 0.278 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
E83.5 Disorders of calcium metabolism
0.722 0.278 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.720 0.280 0.000
N81.5 Vaginal enterocele
0.719 0.280 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.719 0.281 0.000
M75.4 Impingement syndrome of shoulder
0.718 0.282 0.000
H55-H59 Other disorders of eye and adnexa
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
T81.9 Unspecified complication of procedure
0.716 0.284 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.716 0.284 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.716 0.284 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M90 Osteopathies in diseases classified elsewhere
0.716 0.284 0.000
C50.0 Nipple and areola
0.716 0.284 0.000
T93 Sequelae of injuries of lower limb
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
N98 Complications associated with artificial fertilisation
0.715 0.285 0.000
N91 Absent, scanty and rare menstruation
0.715 0.285 0.000
N82 Fistulae involving female genital tract
0.715 0.285 0.000
N96 Habitual aborter
0.715 0.285 0.000
M67.8 Other specified disorders of synovium and tendon
0.715 0.285 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.714 0.286 0.000
E50-E64 Other nutritional deficiencies
0.714 0.286 0.000
M34 Systemic sclerosis
0.713 0.287 0.000
Z48 Other surgical follow-up care
0.713 0.287 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.713 0.287 0.000
N81.9 Female genital prolapse, unspecified
0.712 0.288 0.000
N81.0 Female urethrocele
0.712 0.288 0.000
B25-B34 Other viral diseases
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
J18.0 Bronchopneumonia, unspecified
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.711 0.289 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.289 0.000
Z34 Supervision of normal pregnancy
0.711 0.289 0.000
C34 Malignant neoplasm of bronchus and lung
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.709 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.290 0.000
M15 Polyarthrosis
0.709 0.291 0.000
Q50-Q56 Congenital malformations of genital organs
0.709 0.291 0.000
M75.0 Adhesive capsulitis of shoulder
0.708 0.292 0.000
N36 Other disorders of urethra
0.707 0.293 0.000
Q60-Q64 Congenital malformations of the urinary system
0.707 0.293 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.707 0.293 0.000
M16.7 Other secondary coxarthrosis
0.707 0.293 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.707 0.293 0.000
M16.5 Other posttraumatic coxarthrosis
0.707 0.293 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.707 0.293 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.707 0.293 0.000
N18.3 Chronic kidney disease, stage 3
0.706 0.294 0.000
N18.8 Other chronic renal failure
0.706 0.294 0.000
N18.1 Chronic kidney disease, stage 1
0.706 0.294 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.706 0.294 0.000
D74 Methaemoglobinaemia
0.706 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.706 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.706 0.294 0.000
J10 Influenza due to identified influenza virus
0.704 0.295 0.000
C50.5 Lower-outer quadrant of breast
0.704 0.296 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.704 0.296 0.000
N18.2 Chronic kidney disease, stage 2
0.704 0.296 0.000
M79.5 Residual foreign body in soft tissue
0.704 0.296 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.296 0.000
M71 Other bursopathies
0.704 0.296 0.000
J98.9 Respiratory disorder, unspecified
0.703 0.297 0.000
N18.4 Chronic kidney disease, stage 4
0.701 0.299 0.000
Z96.8 Presence of other specified functional implants
0.701 0.299 0.000
M24 Other specific joint derangements
0.700 0.300 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
G90-G99 Other disorders of the nervous system
0.700 0.300 0.000
M21.3 Wrist or foot drop (acquired)
0.700 0.300 0.000
J45 Asthma
0.700 0.300 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.699 0.300 0.000
Y83.5 Amputation of limb(s)
0.699 0.300 0.000
Y83.0 Surgical operation with transplant of whole organ
0.699 0.300 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.697 0.302 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.697 0.303 0.000
M54.1 Radiculopathy
0.697 0.303 0.000
Z85 Personal history of malignant neoplasm
0.697 0.303 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.694 0.306 0.000
S80.9 Superficial injury of lower leg, unspecified
0.693 0.307 0.000
M79.1 Myalgia
0.692 0.308 0.000
N73.6 Female pelvic peritoneal adhesions
0.692 0.308 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.692 0.308 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.691 0.309 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.691 0.309 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.690 0.310 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.690 0.310 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
M54.50 Low back pain (Multiple sites in spine)
0.689 0.311 0.000
J93 Pneumothorax
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
L03 Cellulitis
0.686 0.314 0.000
I73 Other peripheral vascular diseases
0.686 0.314 0.000
E40-E46 Malnutrition
0.685 0.315 0.000
C50.6 Axillary tail of breast
0.685 0.315 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.315 0.000
I74 Arterial embolism and thrombosis
0.684 0.316 0.000
N17.8 Other acute renal failure
0.683 0.317 0.000
N17.2 Acute renal failure with medullary necrosis
0.683 0.317 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.683 0.317 0.000
N17.0 Acute renal failure with tubular necrosis
0.683 0.317 0.000
Z73 Problems related to life-management difficulty
0.683 0.317 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
O74 Complications of anaesthesia during labour and delivery
0.683 0.317 0.000
O73 Retained placenta and membranes, without haemorrhage
0.683 0.317 0.000
O71 Other obstetric trauma
0.683 0.317 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.683 0.317 0.000
O61 Failed induction of labour
0.683 0.317 0.000
O60 Preterm delivery
0.683 0.317 0.000
E85 Amyloidosis
0.682 0.317 0.000
E84 Cystic fibrosis
0.682 0.317 0.000
E79 Disorders of purine and pyrimidine metabolism
0.682 0.317 0.000
E77 Disorders of glycoprotein metabolism
0.682 0.317 0.000
E76 Disorders of glycosaminoglycan metabolism
0.682 0.317 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.682 0.317 0.000
E74 Other disorders of carbohydrate metabolism
0.682 0.317 0.000
E73 Lactose intolerance
0.682 0.317 0.000
E72 Other disorders of amino-acid metabolism
0.682 0.317 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.682 0.317 0.000
E70 Disorders of aromatic amino-acid metabolism
0.682 0.317 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.682 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.682 0.318 0.000
J17 Pneumonia in diseases classified elsewhere
0.682 0.318 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.682 0.318 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.682 0.318 0.000
J12 Viral pneumonia, not elsewhere classified
0.682 0.318 0.000
J11 Influenza, virus not identified
0.682 0.318 0.000
J14 Pneumonia due to Haemophilus influenzae
0.682 0.318 0.000
J09 Influenza due to certain identified influenza virus
0.682 0.318 0.000
E78.0 Pure hypercholesterolaemia
0.680 0.320 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.678 0.322 0.000
Z43 Attention to artificial openings
0.678 0.322 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.678 0.322 0.000
E87.4 Mixed disorder of acid-base balance
0.678 0.322 0.000
E87.3 Alkalosis
0.678 0.322 0.000
S80.8 Other superficial injuries of lower leg
0.678 0.322 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.678 0.322 0.000
H40.0 Glaucoma suspect
0.677 0.323 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
M05 Seropositive rheumatoid arthritis
0.676 0.324 0.000
D60-D64 Aplastic and other anaemias
0.676 0.324 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.675 0.324 0.000
O72 Postpartum haemorrhage
0.675 0.325 0.000
J80 Adult respiratory distress syndrome
0.675 0.325 0.000
Z96.2 Presence of otological and audiological implants
0.675 0.325 0.000
M19 Other arthrosis
0.674 0.326 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.673 0.326 0.000
C95 Leukaemia of unspecified cell type
0.673 0.326 0.000
C94 Other leukaemias of specified cell type
0.673 0.326 0.000
C93 Monocytic leukaemia
0.673 0.326 0.000
C88 Malignant immunoproliferative diseases
0.673 0.326 0.000
C86 Other specified types of T/NK-cell lymphoma
0.673 0.326 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.673 0.326 0.000
C81 Hodgkin's disease
0.673 0.326 0.000
Z74 Problems related to care-provider dependency
0.673 0.327 0.000
J45.9 Asthma, unspecified
0.673 0.327 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.672 0.327 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
M12 Other specific arthropathies
0.672 0.328 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.672 0.328 0.000
M08 Juvenile arthritis
0.672 0.328 0.000
Z54 Convalescence
0.671 0.329 0.000
Z52 Donors of organs and tissues
0.671 0.329 0.000
Z44 Fitting and adjustment of external prosthetic device
0.671 0.329 0.000
D50-D53 Nutritional anaemias
0.671 0.329 0.000
S82 Fracture of lower leg, including ankle
0.670 0.330 0.000
N88 Other noninflammatory disorders of cervix uteri
0.670 0.330 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.669 0.330 0.000
S89 Other and unspecified injuries of lower leg
0.669 0.331 0.000
S88 Traumatic amputation of lower leg
0.669 0.331 0.000
S87 Crushing injury of lower leg
0.669 0.331 0.000
S86 Injury of muscle and tendon at lower leg level
0.669 0.331 0.000
S85 Injury of blood vessels at lower leg level
0.669 0.331 0.000
S84 Injury of nerves at lower leg level
0.669 0.331 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.669 0.331 0.000
M33 Dermatopolymyositis
0.669 0.331 0.000
M32 Systemic lupus erythematosus
0.669 0.331 0.000
M30 Polyarteritis nodosa and related conditions
0.669 0.331 0.000
N99-N99 Other disorders of the genitourinary system
0.668 0.332 0.000
M54.4 Lumbago with sciatica
0.668 0.332 0.000
Y43 Primarily systemic agents
0.668 0.332 0.000
H35 Other retinal disorders
0.667 0.333 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.667 0.333 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.667 0.333 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.667 0.333 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.667 0.333 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.667 0.333 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.667 0.333 0.000
A41 Other septicaemia
0.667 0.333 0.000
Y44 Agents primarily affecting blood constituents
0.666 0.333 0.000
E20-E35 Disorders of other endocrine glands
0.666 0.334 0.000
M11 Other crystal arthropathies
0.666 0.334 0.000
N37 Urethral disorders in diseases classified elsewhere
0.665 0.334 0.000
N33 Bladder disorders in diseases classified elsewhere
0.665 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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