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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75562644
log Bayes Factor = 16.3598
Chromosome 11   position 132,992,755  (GRCh37) Explore rs75562644 on Ensembl!
Variant rs75562644 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
J90-J94 Other diseases of pleura
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
J90 Pleural effusion, not elsewhere classified
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.991 0.009 0.000
M25 Other joint disorders, not elsewhere classified
0.991 0.009 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.989 0.011 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.989 0.011 0.000
C15-C26 Malignant neoplasms of digestive organs
0.989 0.011 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
M23 Internal derangement of knee
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
E16 Other disorders of pancreatic internal secretion
0.982 0.018 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
M86-M90 Other osteopathies
0.978 0.022 0.000
E65-E68 Obesity and other hyperalimentation
0.978 0.022 0.000
J09-J18 Influenza and pneumonia
0.976 0.024 0.000
M70-M79 Other soft tissue disorders
0.974 0.026 0.000
M25.7 Osteophyte
0.973 0.027 0.000
E16.2 Hypoglycaemia, unspecified
0.973 0.027 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.972 0.028 0.000
C15 Malignant neoplasm of oesophagus
0.963 0.037 0.000
M25.77 Osteophyte (Ankle and foot)
0.962 0.038 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.961 0.039 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.954 0.046 0.000
E66 Obesity
0.954 0.046 0.000
M89 Other disorders of bone
0.954 0.046 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.948 0.052 0.000
E10-E14 Diabetes mellitus
0.947 0.053 0.000
J93 Pneumothorax
0.944 0.056 0.000
G20-G26 Extrapyramidal and movement disorders
0.942 0.058 0.000
M23.3 Other meniscus derangements
0.940 0.060 0.000
D68 Other coagulation defects
0.938 0.062 0.000
E66.8 Other obesity
0.933 0.067 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.929 0.071 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.923 0.077 0.000
M25.4 Effusion of joint
0.922 0.078 0.000
M75 Shoulder lesions
0.921 0.079 0.000
M89.9 Disorder of bone, unspecified
0.919 0.081 0.000
J93.9 Pneumothorax, unspecified
0.917 0.083 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.916 0.084 0.000
C50-C50 Malignant neoplasm of breast
0.914 0.086 0.000
J95-J99 Other diseases of the respiratory system
0.914 0.086 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.914 0.086 0.000
S20-S29 Injuries to the thorax
0.912 0.088 0.000
S90-S99 Injuries to the ankle and foot
0.912 0.088 0.000
G62 Other polyneuropathies
0.911 0.089 0.000
J18 Pneumonia, organism unspecified
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.910 0.090 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
M75.0 Adhesive capsulitis of shoulder
0.909 0.091 0.000
A30-A49 Other bacterial diseases
0.905 0.095 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.902 0.098 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.902 0.098 0.000
M23.4 Loose body in knee
0.901 0.099 0.000
B25-B34 Other viral diseases
0.900 0.100 0.000
Y43 Primarily systemic agents
0.900 0.100 0.000
C15.9 Oesophagus, unspecified
0.899 0.101 0.000
D00-D09 In situ neoplasms
0.899 0.101 0.000
C20 Malignant neoplasm of rectum
0.886 0.114 0.000
J91 Pleural effusion in conditions classified elsewhere
0.885 0.115 0.000
C92 Myeloid leukaemia
0.884 0.116 0.000
C15.5 Lower third of oesophagus
0.884 0.116 0.000
M05-M14 Inflammatory polyarthropathies
0.878 0.122 0.000
C78.2 Secondary malignant neoplasm of pleura
0.875 0.125 0.000
M79.0 Rheumatism, unspecified
0.875 0.125 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.873 0.127 0.000
J94 Other pleural conditions
0.872 0.128 0.000
G20 Parkinson's disease
0.870 0.130 0.000
G24 Dystonia
0.869 0.131 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.861 0.139 0.000
Y52 Agents primarily affecting the cardiovascular system
0.861 0.139 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.859 0.141 0.000
C78.0 Secondary malignant neoplasm of lung
0.857 0.143 0.000
J98 Other respiratory disorders
0.854 0.146 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.854 0.146 0.000
C50 Malignant neoplasm of breast
0.853 0.147 0.000
E10 Insulin-dependent diabetes mellitus
0.852 0.148 0.000
M31 Other necrotising vasculopathies
0.851 0.149 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.851 0.149 0.000
J18.0 Bronchopneumonia, unspecified
0.850 0.150 0.000
D68.9 Coagulation defect, unspecified
0.849 0.151 0.000
T81 Complications of procedures, not elsewhere classified
0.847 0.153 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.843 0.157 0.000
D60-D64 Aplastic and other anaemias
0.843 0.157 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.841 0.159 0.000
M91-M94 Chondropathies
0.840 0.160 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.840 0.160 0.000
M23.49 Loose body in knee-Unspec lig/men
0.839 0.161 0.000
M87 Osteonecrosis
0.839 0.161 0.000
C18 Malignant neoplasm of colon
0.836 0.164 0.000
M25.46 Effusion of joint (Lower leg)
0.834 0.166 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.834 0.166 0.000
A41 Other septicaemia
0.833 0.167 0.000
G62.9 Polyneuropathy, unspecified
0.832 0.168 0.000
B50-B64 Protozoal diseases
0.827 0.173 0.000
Y40 Systemic antibiotics
0.827 0.173 0.000
G90-G99 Other disorders of the nervous system
0.827 0.173 0.000
E11 Non-insulin-dependent diabetes mellitus
0.824 0.176 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.824 0.176 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.824 0.176 0.000
C77.1 Intrathoracic lymph nodes
0.822 0.178 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.821 0.179 0.000
B95-B98 Bacterial, viral and other infectious agents
0.819 0.181 0.000
Y43.3 Other antineoplastic drugs
0.819 0.181 0.000
D05 Carcinoma in situ of breast
0.817 0.183 0.000
M21 Other acquired deformities of limbs
0.815 0.185 0.000
C77.2 Intra-abdominal lymph nodes
0.812 0.188 0.000
B34 Viral infection of unspecified site
0.810 0.190 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.806 0.194 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.804 0.196 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.804 0.196 0.000
J18.1 Lobar pneumonia, unspecified
0.802 0.198 0.000
D80-D89 Certain disorders involving the immune mechanism
0.802 0.198 0.000
E65 Localised adiposity
0.800 0.200 0.000
J17 Pneumonia in diseases classified elsewhere
0.799 0.201 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.797 0.203 0.000
M79.8 Other specified soft tissue disorders
0.795 0.205 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.795 0.205 0.000
B99-B99 Other infectious diseases
0.795 0.205 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.794 0.206 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.793 0.207 0.000
M11 Other crystal arthropathies
0.793 0.207 0.000
G62.8 Other specified polyneuropathies
0.792 0.207 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.792 0.208 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.792 0.208 0.000
Y95 Nosocomial condition
0.792 0.208 0.000
C21 Malignant neoplasm of anus and anal canal
0.791 0.209 0.000
B35-B49 Mycoses
0.791 0.209 0.000
T86 Failure and rejection of transplanted organs and tissues
0.790 0.210 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.789 0.211 0.000
M89.8 Other specified disorders of bone
0.788 0.212 0.000
X60-X84 Intentional self-harm
0.787 0.213 0.000
D68.2 Hereditary deficiency of other clotting factors
0.786 0.214 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.785 0.215 0.000
A63.0 Anogenital (venereal) warts
0.785 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.785 0.215 0.000
T82.3 Mechanical complication of other vascular grafts
0.784 0.215 0.000
J14 Pneumonia due to Haemophilus influenzae
0.784 0.216 0.000
M25.72 Osteophyte (Upper arm)
0.784 0.216 0.000
M45-M49 Spondylopathies
0.783 0.217 0.000
C23 Malignant neoplasm of gallbladder
0.783 0.217 0.000
C83.3 Large cell (diffuse)
0.781 0.219 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.780 0.220 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.780 0.220 0.000
C92.0 Acute myeloid leukaemia
0.780 0.220 0.000
C91 Lymphoid leukaemia
0.779 0.221 0.000
M23.5 Chronic instability of knee
0.777 0.223 0.000
M25.47 Effusion of joint (Ankle and foot)
0.776 0.224 0.000
M25.8 Other specified joint disorders
0.775 0.225 0.000
M60-M63 Disorders of muscles
0.774 0.226 0.000
J10 Influenza due to identified influenza virus
0.773 0.227 0.000
A40 Streptococcal septicaemia
0.772 0.228 0.000
M32 Systemic lupus erythematosus
0.770 0.230 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.769 0.231 0.000
D68.6 Other Thrombophilia
0.768 0.232 0.000
C45 Mesothelioma
0.767 0.233 0.000
G60 Hereditary and idiopathic neuropathy
0.766 0.234 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.766 0.234 0.000
D68.0 Von Willebrand's disease
0.765 0.235 0.000
Q80-Q89 Other congenital malformations
0.765 0.235 0.000
E34 Other endocrine disorders
0.764 0.236 0.000
G40-G47 Episodic and paroxysmal disorders
0.764 0.236 0.000
M20 Acquired deformities of fingers and toes
0.764 0.236 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.763 0.237 0.000
C92.1 Chronic myeloid leukaemia
0.763 0.237 0.000
M22 Disorders of patella
0.763 0.237 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.763 0.237 0.000
S27 Injury of other and unspecified intrathoracic organs
0.762 0.238 0.000
B07 Viral warts
0.762 0.238 0.000
C79 Secondary malignant neoplasm of other sites
0.760 0.240 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.760 0.240 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.760 0.240 0.000
D66 Hereditary factor VIII deficiency
0.760 0.240 0.000
D55-D59 Haemolytic anaemias
0.760 0.240 0.000
M25.78 Osteophyte (Other)
0.759 0.240 0.000
D05.1 Intraductal carcinoma in situ
0.759 0.241 0.000
S90 Superficial injury of ankle and foot
0.756 0.244 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.755 0.245 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.754 0.246 0.000
E22 Hyperfunction of pituitary gland
0.754 0.246 0.000
M25.76 Osteophyte (Lower leg)
0.754 0.246 0.000
C77.3 Axillary and upper limb lymph nodes
0.753 0.247 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.752 0.248 0.000
M25.0 Haemarthrosis
0.751 0.249 0.000
J98.8 Other specified respiratory disorders
0.750 0.250 0.000
X50-X57 Overexertion, travel and privation
0.750 0.250 0.000
M23.9 Internal derangement of knee, unspecified
0.750 0.250 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.749 0.250 0.000
B02 Zoster [herpes zoster]
0.748 0.252 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.747 0.253 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.253 0.000
M76 Enthesopathies of lower limb, excluding foot
0.747 0.253 0.000
M10 Gout
0.746 0.254 0.000
V20-V29 Motorcycle rider injured in transport accident
0.746 0.254 0.000
D68.5 Primary Thrombophilia
0.745 0.255 0.000
M65-M68 Disorders of synovium and tendon
0.743 0.257 0.000
B34.9 Viral infection, unspecified
0.742 0.258 0.000
C18.3 Hepatic flexure
0.742 0.258 0.000
C50.3 Lower-inner quadrant of breast
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
J94.8 Other specified pleural conditions
0.741 0.259 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.741 0.259 0.000
C50.1 Central portion of breast
0.740 0.260 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.740 0.260 0.000
E40-E46 Malnutrition
0.740 0.260 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.739 0.261 0.000
M87.9 Osteonecrosis, unspecified
0.739 0.261 0.000
J81 Pulmonary oedema
0.739 0.261 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.738 0.261 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.738 0.262 0.000
M71 Other bursopathies
0.737 0.262 0.000
Chapter XXII Codes for special purposes
0.737 0.263 0.000
M75.5 Bursitis of shoulder
0.736 0.264 0.000
E66.9 Obesity, unspecified
0.736 0.264 0.000
E10.3 With ophthalmic complications
0.735 0.265 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.735 0.265 0.000
G24.9 Dystonia, unspecified
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.266 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.734 0.266 0.000
J98.1 Pulmonary collapse
0.733 0.267 0.000
M89.5 Osteolysis
0.732 0.268 0.000
C17 Malignant neoplasm of small intestine
0.732 0.268 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
M11.2 Other chondrocalcinosis
0.731 0.269 0.000
G24.8 Other dystonia
0.731 0.269 0.000
S91 Open wound of ankle and foot
0.730 0.270 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.730 0.270 0.000
S50-S59 Injuries to the elbow and forearm
0.730 0.270 0.000
S92 Fracture of foot, except ankle
0.730 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.729 0.270 0.000
M75.1 Rotator cuff syndrome
0.729 0.271 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.728 0.272 0.000
C18.2 Ascending colon
0.728 0.272 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.727 0.272 0.000
V80-V89 Other land transport accidents
0.723 0.276 0.000
Y43.4 Immunosuppressive agents
0.723 0.277 0.000
S20 Superficial injury of thorax
0.723 0.277 0.000
S40-S49 Injuries to the shoulder and upper arm
0.722 0.278 0.000
G62.0 Drug-induced polyneuropathy
0.722 0.278 0.000
D06 Carcinoma in situ of cervix uteri
0.721 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.720 0.280 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.720 0.280 0.000
C16 Malignant neoplasm of stomach
0.719 0.281 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M90 Osteopathies in diseases classified elsewhere
0.716 0.283 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.716 0.284 0.000
M25.3 Other instability of joint
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.714 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.286 0.000
M31.6 Other giant cell arteritis
0.713 0.287 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.713 0.287 0.000
Chapter VII Diseases of the eye and adnexa
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.287 0.000
G61 Inflammatory polyneuropathy
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.711 0.289 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.710 0.290 0.000
M25.9 Joint disorder, unspecified
0.710 0.290 0.000
M25.2 Flail joint
0.710 0.290 0.000
M25.1 Fistula of joint
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.709 0.291 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.709 0.291 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.709 0.291 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.709 0.291 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.709 0.291 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
M23.1 Discoid meniscus (congenital)
0.708 0.292 0.000
M23.0 Cystic meniscus
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.707 0.292 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.707 0.293 0.000
S29 Other and unspecified injuries of thorax
0.707 0.293 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.706 0.294 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.706 0.294 0.000
G82 Paraplegia and tetraplegia
0.705 0.295 0.000
C64-C68 Malignant neoplasms of urinary tract
0.705 0.295 0.000
B59 Pneumocystosis
0.705 0.295 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.704 0.296 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.704 0.296 0.000
E16.4 Abnormal secretion of gastrin
0.704 0.296 0.000
E16.3 Increased secretion of glucagon
0.704 0.296 0.000
E16.1 Other hypoglycaemia
0.704 0.296 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
J11 Influenza, virus not identified
0.704 0.296 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.704 0.296 0.000
E11.3 With ophthalmic complications
0.703 0.297 0.000
B25 Cytomegaloviral disease
0.702 0.297 0.000
Y45.0 Opioids and related analgesics
0.702 0.298 0.000
M94 Other disorders of cartilage
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.298 0.000
Y58 Bacterial vaccines
0.701 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.298 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.298 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.701 0.298 0.000
E67 Other hyperalimentation
0.701 0.299 0.000
E68 Sequelae of hyperalimentation
0.701 0.299 0.000
J94.2 Haemothorax
0.701 0.299 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.701 0.299 0.000
C78.7 Secondary malignant neoplasm of liver
0.701 0.299 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.700 0.300 0.000
J12 Viral pneumonia, not elsewhere classified
0.700 0.300 0.000
J09 Influenza due to certain identified influenza virus
0.700 0.300 0.000
E13 Other specified diabetes mellitus
0.700 0.300 0.000
C77.4 Inguinal and lower limb lymph nodes
0.699 0.301 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
B01 Varicella [chickenpox]
0.699 0.301 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.698 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.698 0.302 0.000
C15.4 Middle third of oesophagus
0.698 0.302 0.000
M25.79 Osteophyte (Site unspecified)
0.698 0.302 0.000
M25.73 Osteophyte (Forearm)
0.698 0.302 0.000
M25.70 Osteophyte (Multiple sites)
0.698 0.302 0.000
E14 Unspecified diabetes mellitus
0.697 0.303 0.000
G24.5 Blepharospasm
0.697 0.303 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.697 0.303 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.697 0.303 0.000
Chapter VIII Diseases of the ear and mastoid process
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
M79.5 Residual foreign body in soft tissue
0.691 0.308 0.000
E11.5 With peripheral circulatory complications
0.692 0.308 0.000
C15.8 Overlapping lesion of oesophagus
0.691 0.309 0.000
C15.3 Upper third of oesophagus
0.691 0.309 0.000
C15.2 Abdominal part of oesophagus
0.691 0.309 0.000
C15.1 Thoracic part of oesophagus
0.691 0.309 0.000
C15.0 Cervical part of oesophagus
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.690 0.309 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
D67 Hereditary factor IX deficiency
0.689 0.311 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.689 0.311 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.689 0.311 0.000
M75.9 Shoulder lesion, unspecified
0.689 0.311 0.000
E10.1 With ketoacidosis
0.688 0.312 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.688 0.312 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.687 0.313 0.000
M79.6 Pain in limb
0.686 0.314 0.000
M88 Paget's disease of bone [osteitis deformans]
0.685 0.314 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
C95 Leukaemia of unspecified cell type
0.684 0.316 0.000
C94 Other leukaemias of specified cell type
0.684 0.316 0.000
C93 Monocytic leukaemia
0.684 0.316 0.000
C88 Malignant immunoproliferative diseases
0.684 0.316 0.000
C86 Other specified types of T/NK-cell lymphoma
0.684 0.316 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.684 0.316 0.000
S80-S89 Injuries to the knee and lower leg
0.684 0.316 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.684 0.316 0.000
E66.1 Drug-induced obesity
0.684 0.316 0.000
E66.0 Obesity due to excess calories
0.684 0.316 0.000
M89.6 Osteopathy after poliomyelitis
0.684 0.316 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.684 0.316 0.000
M89.3 Hypertrophy of bone
0.684 0.316 0.000
M89.2 Other disorders of bone development and growth
0.684 0.316 0.000
M89.1 Epiphyseal arrest
0.684 0.316 0.000
M89.0 Algoneurodystrophy
0.684 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.684 0.316 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.681 0.319 0.000
J98.4 Other disorders of lung
0.680 0.320 0.000
G64 Other disorders of peripheral nervous system
0.680 0.320 0.000
E12 Malnutrition-related diabetes mellitus
0.679 0.321 0.000
C50.0 Nipple and areola
0.678 0.322 0.000
J93.0 Spontaneous tension pneumothorax
0.677 0.323 0.000
C45.9 Mesothelioma, unspecified
0.676 0.324 0.000
D61 Other aplastic anaemias
0.675 0.324 0.000
G23 Other degenerative diseases of basal ganglia
0.675 0.325 0.000
G21 Secondary Parkinsonism
0.675 0.325 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.675 0.325 0.000
G22 Parkinsonism in diseases classified elsewhere
0.675 0.325 0.000
M79.2 Neuralgia and neuritis, unspecified
0.675 0.325 0.000
E24 Cushing's syndrome
0.675 0.325 0.000
A48 Other bacterial diseases, not elsewhere classified
0.674 0.325 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.674 0.326 0.000
M23.37 Other meniscus derangements-Capsular lig
0.674 0.326 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.674 0.326 0.000
J93.8 Other pneumothorax
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.326 0.000
D68.4 Acquired coagulation factor deficiency
0.673 0.327 0.000
D68.1 Hereditary factor XI deficiency
0.673 0.327 0.000
E28 Ovarian dysfunction
0.672 0.328 0.000
J17.3 Pneumonia in parasitic diseases
0.671 0.329 0.000
M47 Spondylosis
0.671 0.329 0.000
G95 Other diseases of spinal cord
0.671 0.329 0.000
W20-W49 Exposure to inanimate mechanical forces
0.670 0.329 0.000
M21.1 Varus deformity, not elsewhere classified
0.670 0.330 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.670 0.330 0.000
E10.2 With renal complications
0.668 0.332 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.668 0.332 0.000
C50.4 Upper-outer quadrant of breast
0.667 0.333 0.000
E21.0 Primary hyperparathyroidism
0.667 0.333 0.000
M07 Psoriatic and enteropathic arthropathies
0.667 0.333 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.667 0.333 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.667 0.333 0.000
M79.9 Soft tissue disorder, unspecified
0.666 0.334 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.666 0.334 0.000
M79.3 Panniculitis, unspecified
0.666 0.334 0.000
M25.74 Osteophyte (Hand)
0.665 0.335 0.000
A80-A89 Viral infections of the central nervous system
0.665 0.335 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.335 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.664 0.336 0.000
M31.3 Wegener's granulomatosis
0.663 0.337 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.663 0.337 0.000
D09 Carcinoma in situ of other and unspecified sites
0.662 0.338 0.000
D69 Purpura and other haemorrhagic conditions
0.662 0.338 0.000
G96 Other disorders of central nervous system
0.662 0.338 0.000
C21.0 Anus, unspecified
0.661 0.338 0.000
M25.49 Effusion of joint (Site unspecified)
0.661 0.339 0.000
M25.48 Effusion of joint (Other)
0.661 0.339 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.661 0.339 0.000
M25.44 Effusion of joint (Hand)
0.661 0.339 0.000
M25.43 Effusion of joint (Forearm)
0.661 0.339 0.000
M25.42 Effusion of joint (Upper arm)
0.661 0.339 0.000
M25.41 Effusion of joint (Shoulder region)
0.661 0.339 0.000
M25.40 Effusion of joint (Multiple sites)
0.661 0.339 0.000
M75.8 Other shoulder lesions
0.660 0.340 0.000
D70 Agranulocytosis
0.660 0.340 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.659 0.341 0.000
M89.98 Disorder of bone, unspecified (Other)
0.659 0.341 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.659 0.341 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.659 0.341 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.659 0.341 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.659 0.341 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.659 0.341 0.000
D68.8 Other specified coagulation defects
0.659 0.341 0.000
Y40.9 Systemic antibiotic, unspecified
0.658 0.342 0.000
M20.1 Hallux valgus (acquired)
0.657 0.343 0.000
E21.3 Hyperparathyroidism, unspecified
0.657 0.343 0.000
E11.1 With ketoacidosis
0.656 0.343 0.000
D04 Carcinoma in situ of skin
0.656 0.344 0.000
J96 Respiratory failure, not elsewhere classified
0.655 0.345 0.000
M34 Systemic sclerosis
0.655 0.345 0.000
C50.2 Upper-inner quadrant of breast
0.654 0.346 0.000
T90 Sequelae of injuries of head
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.346 0.000
S26 Injury of heart
0.654 0.346 0.000
S25 Injury of blood vessels of thorax
0.654 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.346 0.000
S21 Open wound of thorax
0.654 0.346 0.000
S98 Traumatic amputation of ankle and foot
0.654 0.346 0.000
S97 Crushing injury of ankle and foot
0.654 0.346 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.654 0.346 0.000
S95 Injury of blood vessels at ankle and foot level
0.654 0.346 0.000
S94 Injury of nerves at ankle and foot level
0.654 0.346 0.000
G62.2 Polyneuropathy due to other toxic agents
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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