TreeWAS – Variant ID: rs75638798

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.957	0.043	0.000
# Top node	0.956	0.044	0.000
Chapter IX Diseases of the circulatory system	0.954	0.046	0.000
M20-M25 Other joint disorders	0.954	0.046	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.953	0.047	0.000
I20-I25 Ischaemic heart diseases	0.951	0.049	0.000
Chapter XIV Diseases of the genitourinary system	0.950	0.050	0.000
M25 Other joint disorders, not elsewhere classified	0.938	0.062	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.937	0.063	0.000
Chapter I Certain infectious and parasitic diseases	0.927	0.073	0.000
I25 Chronic ischaemic heart disease	0.917	0.083	0.000
N40-N51 Diseases of male genital organs	0.917	0.083	0.000
I21 Acute myocardial infarction	0.908	0.092	0.000
N20-N23 Urolithiasis	0.905	0.095	0.000
B95-B98 Bacterial, viral and other infectious agents	0.902	0.098	0.000
N40 Hyperplasia of prostate	0.898	0.102	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.893	0.107	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.892	0.108	0.000
M25.5 Pain in joint	0.883	0.117	0.000
I25.2 Old myocardial infarction	0.881	0.119	0.000
N23 Unspecified renal colic	0.880	0.120	0.000
M20 Acquired deformities of fingers and toes	0.860	0.140	0.000
I25.1 Atherosclerotic heart disease	0.856	0.144	0.000
S60-S69 Injuries to the wrist and hand	0.849	0.151	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.838	0.162	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.837	0.163	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.835	0.165	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.835	0.165	0.000
N41 Inflammatory diseases of prostate	0.831	0.169	0.000
I95 Hypotension	0.825	0.175	0.000
M45-M49 Spondylopathies	0.824	0.176	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.823	0.177	0.000
M70-M79 Other soft tissue disorders	0.822	0.178	0.000
N00-N08 Glomerular diseases	0.820	0.180	0.000
N99-N99 Other disorders of the genitourinary system	0.810	0.190	0.000
I60-I69 Cerebrovascular diseases	0.805	0.195	0.000
M20.5 Other deformities of toe(s) (acquired)	0.804	0.196	0.000
Chapter XX External causes of morbidity and mortality	0.804	0.196	0.000
S40-S49 Injuries to the shoulder and upper arm	0.800	0.200	0.000
N17-N19 Renal failure	0.798	0.202	0.000
B35-B49 Mycoses	0.798	0.202	0.000
M65-M68 Disorders of synovium and tendon	0.793	0.207	0.000
I21.4 Acute subendocardial myocardial infarction	0.791	0.209	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216	0.000
S80-S89 Injuries to the knee and lower leg	0.780	0.220	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.779	0.221	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.776	0.223	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.775	0.225	0.000
M25.56 Pain in joint (Lower leg)	0.771	0.229	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.768	0.232	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.766	0.234	0.000
M25.7 Osteophyte	0.766	0.234	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.764	0.235	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.761	0.239	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.760	0.240	0.000
N25-N29 Other disorders of kidney and ureter	0.758	0.242	0.000
N41.1 Chronic prostatitis	0.758	0.242	0.000
I22 Subsequent myocardial infarction	0.757	0.243	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.756	0.244	0.000
M35 Other systemic involvement of connective tissue	0.753	0.247	0.000
M21 Other acquired deformities of limbs	0.753	0.247	0.000
M25.50 Pain in joint (Multiple sites)	0.751	0.249	0.000
M24 Other specific joint derangements	0.750	0.250	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.750	0.250	0.000
I63 Cerebral infarction	0.749	0.251	0.000
N60-N64 Disorders of breast	0.748	0.252	0.000
S62 Fracture at wrist and hand level	0.745	0.255	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.744	0.256	0.000
N43 Hydrocele and spermatocele	0.744	0.256	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.743	0.257	0.000
S90-S99 Injuries to the ankle and foot	0.743	0.257	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.737	0.263	0.000
M25.57 Pain in joint (Ankle and foot)	0.735	0.265	0.000
M05-M14 Inflammatory polyarthropathies	0.733	0.267	0.000
I95.9 Hypotension, unspecified	0.733	0.267	0.000
I21.9 Acute myocardial infarction, unspecified	0.732	0.268	0.000
M86-M90 Other osteopathies	0.728	0.272	0.000
M31 Other necrotising vasculopathies	0.726	0.274	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.726	0.274	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.720	0.280	0.000
I24 Other acute ischaemic heart diseases	0.717	0.283	0.000
I20 Angina pectoris	0.715	0.285	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.711	0.289	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.710	0.290	0.000
N19 Unspecified renal failure	0.709	0.291	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.709	0.291	0.000
M47 Spondylosis	0.707	0.293	0.000
B37 Candidiasis	0.706	0.294	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.705	0.295	0.000
M79.8 Other specified soft tissue disorders	0.704	0.296	0.000
M25.8 Other specified joint disorders	0.703	0.297	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.703	0.297	0.000
M80-M85 Disorders of bone density and structure	0.703	0.297	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.699	0.301	0.000
M25.4 Effusion of joint	0.696	0.304	0.000
S70-S79 Injuries to the hip and thigh	0.696	0.304	0.000
N42 Other disorders of prostate	0.696	0.304	0.000
T79-T79 Certain early complications of trauma	0.691	0.309	0.000
I95.1 Orthostatic hypotension	0.689	0.311	0.000
N41.0 Acute prostatitis	0.688	0.311	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.687	0.313	0.000
M91-M94 Chondropathies	0.686	0.314	0.000
M60-M63 Disorders of muscles	0.686	0.314	0.000
M00-M03 Infectious arthropathies	0.686	0.314	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.685	0.315	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.685	0.315	0.000
I00-I02 Acute rheumatic fever	0.684	0.316	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.684	0.316	0.000
M34 Systemic sclerosis	0.684	0.316	0.000
M33 Dermatopolymyositis	0.684	0.316	0.000
M32 Systemic lupus erythematosus	0.684	0.316	0.000
M30 Polyarteritis nodosa and related conditions	0.684	0.316	0.000
T33-T35 Frostbite	0.683	0.316	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.683	0.316	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.683	0.316	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.683	0.316	0.000
T00-T07 Injuries involving multiple body regions	0.683	0.316	0.000
S10-S19 Injuries to the neck	0.683	0.316	0.000
N03 Chronic nephritic syndrome	0.683	0.317	0.000
Chapter VII Diseases of the eye and adnexa	0.682	0.318	0.000
I23 Certain current complications following acute myocardial infarction	0.682	0.318	0.000
M20.4 Other hammer toe(s) (acquired)	0.682	0.318	0.000
B15-B19 Viral hepatitis	0.681	0.319	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.681	0.319	0.000
I99 Other and unspecified disorders of circulatory system	0.680	0.319	0.000
S42 Fracture of shoulder and upper arm	0.680	0.320	0.000
Chapter XXII Codes for special purposes	0.678	0.322	0.000
M25.9 Joint disorder, unspecified	0.673	0.327	0.000
M25.3 Other instability of joint	0.673	0.327	0.000
M25.2 Flail joint	0.673	0.327	0.000
M25.1 Fistula of joint	0.673	0.327	0.000
M25.0 Haemarthrosis	0.673	0.327	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.672	0.328	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.672	0.328	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.672	0.328	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.672	0.328	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.672	0.328	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.672	0.328	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.672	0.328	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.672	0.328	0.000
T36 Poisoning by systemic antibiotics	0.672	0.328	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.671	0.329	0.000
N64 Other disorders of breast	0.668	0.332	0.000
M46 Other inflammatory spondylopathies	0.668	0.332	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.667	0.333	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.666	0.333	0.000
I63.9 Cerebral infarction, unspecified	0.666	0.334	0.000
B07 Viral warts	0.664	0.336	0.000
B99-B99 Other infectious diseases	0.664	0.336	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.664	0.336	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.664	0.336	0.000
B65-B83 Helminthiases	0.664	0.336	0.000
B50-B64 Protozoal diseases	0.664	0.336	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.664	0.336	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.664	0.336	0.000
A80-A89 Viral infections of the central nervous system	0.664	0.336	0.000
A75-A79 Rickettsioses	0.664	0.336	0.000
A70-A74 Other diseases caused by chlamydiae	0.664	0.336	0.000
A65-A69 Other spirochaetal diseases	0.664	0.336	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.664	0.336	0.000
A20-A28 Certain zoonotic bacterial diseases	0.664	0.336	0.000
A15-A19 Tuberculosis	0.664	0.336	0.000
M20.1 Hallux valgus (acquired)	0.664	0.336	0.000
W20-W49 Exposure to inanimate mechanical forces	0.663	0.337	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.662	0.338	0.000
N02 Recurrent and persistent haematuria	0.661	0.339	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.660	0.340	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.658	0.342	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.658	0.342	0.000
I25.6 Silent myocardial ischaemia	0.658	0.342	0.000
I25.5 Ischaemic cardiomyopathy	0.658	0.342	0.000
I25.4 Coronary artery aneurysm	0.658	0.342	0.000
I25.3 Aneurysm of heart	0.658	0.342	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.658	0.342	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.657	0.342	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.657	0.342	0.000
N46 Male infertility	0.657	0.342	0.000
N44 Torsion of testis	0.657	0.342	0.000
M40-M43 Deforming dorsopathies	0.657	0.343	0.000
T43.2 Other and unspecified antidepressants	0.656	0.344	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.654	0.346	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.651	0.349	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.651	0.349	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.651	0.349	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.649	0.351	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.649	0.351	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.649	0.351	0.000
B25-B34 Other viral diseases	0.648	0.352	0.000
I60 Subarachnoid haemorrhage	0.646	0.354	0.000
M65 Synovitis and tenosynovitis	0.644	0.356	0.000
X60-X84 Intentional self-harm	0.643	0.357	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.640	0.360	0.000
I05-I09 Chronic rheumatic heart diseases	0.640	0.360	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.639	0.360	0.000
M22 Disorders of patella	0.638	0.362	0.000
N20 Calculus of kidney and ureter	0.638	0.362	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.637	0.363	0.000
T66-T78 Other and unspecified effects of external causes	0.635	0.365	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.635	0.365	0.000
M25.59 Pain in joint (Site unspecified)	0.633	0.366	0.000
M25.58 Pain in joint (Other)	0.633	0.366	0.000
M25.54 Pain in joint (Hand)	0.633	0.366	0.000
M25.52 Pain in joint (Upper arm)	0.633	0.366	0.000
S69 Other and unspecified injuries of wrist and hand	0.631	0.369	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.630	0.370	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.630	0.370	0.000
M23 Internal derangement of knee	0.629	0.371	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.629	0.371	0.000
M25.77 Osteophyte (Ankle and foot)	0.629	0.371	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.628	0.372	0.000
N60 Benign mammary dysplasia	0.627	0.372	0.000
T39.1 4-Aminophenol derivatives	0.627	0.373	0.000
M35.0 Sicca syndrome [Sjogren]	0.626	0.374	0.000
M06 Other rheumatoid arthritis	0.626	0.374	0.000
T90 Sequelae of injuries of head	0.626	0.374	0.000
N45 Orchitis and epididymitis	0.625	0.375	0.000
M25.51 Pain in joint (Shoulder region)	0.625	0.375	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.624	0.376	0.000
Chapter V Mental and behavioural disorders	0.623	0.377	0.000
S50-S59 Injuries to the elbow and forearm	0.623	0.377	0.000
T51 Toxic effect of alcohol	0.622	0.378	0.000
T39.0 Salicylates	0.622	0.378	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.621	0.379	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.620	0.379	0.000
N43.3 Hydrocele, unspecified	0.620	0.380	0.000
M50-M54 Other dorsopathies	0.618	0.382	0.000
M67 Other disorders of synovium and tendon	0.617	0.383	0.000
M20.3 Other deformity of hallux (acquired)	0.616	0.383	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.616	0.384	0.000
I30-I52 Other forms of heart disease	0.615	0.385	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.615	0.385	0.000
B37.8 Candidiasis of other sites	0.615	0.385	0.000
S64 Injury of nerves at wrist and hand level	0.615	0.385	0.000
I95.2 Hypotension due to drugs	0.614	0.386	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.612	0.388	0.000
N17 Acute renal failure	0.610	0.390	0.000
N10-N16 Renal tubulo-interstitial diseases	0.609	0.391	0.000
S62.5 Fracture of thumb	0.609	0.391	0.000
S67 Crushing injury of wrist and hand	0.608	0.392	0.000
S65 Injury of blood vessels at wrist and hand level	0.608	0.392	0.000
S60 Superficial injury of wrist and hand	0.608	0.392	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.608	0.392	0.000
M47.2 Other spondylosis with radiculopathy	0.607	0.393	0.000
I24.8 Other forms of acute ischaemic heart disease	0.607	0.393	0.000
I72 Other aneurysm	0.607	0.393	0.000
M24.1 Other articular cartilage disorders	0.604	0.396	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.602	0.398	0.000
N21 Calculus of lower urinary tract	0.602	0.398	0.000
M05 Seropositive rheumatoid arthritis	0.602	0.398	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.601	0.398	0.000
T43.9 Psychotropic drug, unspecified	0.600	0.400	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.600	0.400	0.000
T43.6 Psychostimulants with abuse potential	0.600	0.400	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.600	0.400	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.600	0.400	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.600	0.400	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.600	0.400	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.599	0.401	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.599	0.401	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.599	0.401	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.599	0.401	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.599	0.401	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.599	0.401	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.599	0.401	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.599	0.401	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.599	0.401	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.599	0.401	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.599	0.401	0.000
T39.4 Antirheumatics, not elsewhere classified	0.599	0.401	0.000
T39.2 Pyrazolone derivatives	0.599	0.401	0.000
M71 Other bursopathies	0.598	0.402	0.000
M25.53 Pain in joint (Forearm)	0.597	0.402	0.000
N41.8 Other inflammatory diseases of prostate	0.596	0.404	0.000
N41.3 Prostatocystitis	0.596	0.404	0.000
N41.2 Abscess of prostate	0.596	0.404	0.000
Q50-Q56 Congenital malformations of genital organs	0.595	0.405	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.594	0.406	0.000
M48 Other spondylopathies	0.592	0.408	0.000
I95.8 Other hypotension	0.592	0.408	0.000
I95.0 Idiopathic hypotension	0.592	0.408	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.591	0.409	0.000
M49 Spondylopathies in diseases classified elsewhere	0.591	0.409	0.000
M77 Other enthesopathies	0.590	0.410	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.590	0.410	0.000
M76 Enthesopathies of lower limb, excluding foot	0.589	0.410	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.589	0.410	0.000
M21.0 Valgus deformity, not elsewhere classified	0.588	0.411	0.000
T93 Sequelae of injuries of lower limb	0.588	0.412	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.588	0.412	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.588	0.412	0.000
N06 Isolated proteinuria with specified morphological lesion	0.588	0.412	0.000
N05 Unspecified nephritic syndrome	0.588	0.412	0.000
N04 Nephrotic syndrome	0.588	0.412	0.000
N01 Rapidly progressive nephritic syndrome	0.588	0.412	0.000
N00 Acute nephritic syndrome	0.588	0.412	0.000
N64.5 Other signs and symptoms in breast	0.588	0.412	0.000
N03.9 Unspecified	0.586	0.414	0.000
M25.76 Osteophyte (Lower leg)	0.586	0.414	0.000
I42 Cardiomyopathy	0.585	0.415	0.000
M20.0 Deformity of finger(s)	0.585	0.415	0.000
S32 Fracture of lumbar spine and pelvis	0.584	0.416	0.000
S20-S29 Injuries to the thorax	0.581	0.418	0.000
N48 Other disorders of penis	0.581	0.419	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.580	0.420	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.579	0.421	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.579	0.421	0.000
W00-W19 Falls	0.578	0.422	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.577	0.422	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.577	0.422	0.000
I61 Intracerebral haemorrhage	0.577	0.422	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.577	0.423	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.576	0.424	0.000
Y35-Y36 Legal intervention and operations of war	0.576	0.424	0.000
Y10-Y34 Event of undetermined intent	0.576	0.424	0.000
Y00-Y09 Assault	0.576	0.424	0.000
X85-X99 Assault	0.576	0.424	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.576	0.424	0.000
X50-X57 Overexertion, travel and privation	0.576	0.424	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.576	0.424	0.000
X30-X39 Exposure to forces of nature	0.576	0.424	0.000
X20-X29 Contact with venomous animals and plants	0.576	0.424	0.000
X10-X19 Contact with heat and hot substances	0.576	0.424	0.000
X00-X09 Exposure to smoke, fire and flames	0.576	0.424	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.576	0.424	0.000
W75-W84 Other accidental threats to breathing	0.576	0.424	0.000
W65-W74 Accidental drowning and submersion	0.576	0.424	0.000
W50-W64 Exposure to animate mechanical forces	0.576	0.424	0.000
V98-V99 Other and unspecified transport accidents	0.576	0.424	0.000
V95-V97 Air and space transport accidents	0.576	0.424	0.000
V90-V94 Water transport accidents	0.576	0.424	0.000
V80-V89 Other land transport accidents	0.576	0.424	0.000
V70-V79 Bus occupant injured in transport accident	0.576	0.424	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.576	0.424	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.576	0.424	0.000
V40-V49 Car occupant injured in transport accident	0.576	0.424	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.576	0.424	0.000
V20-V29 Motorcycle rider injured in transport accident	0.576	0.424	0.000
V01-V09 Pedestrian injured in transport accident	0.576	0.424	0.000
M75 Shoulder lesions	0.576	0.424	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.574	0.426	0.000
S48 Traumatic amputation of shoulder and upper arm	0.574	0.426	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.574	0.426	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.574	0.426	0.000
S44 Injury of nerves at shoulder and upper arm level	0.574	0.426	0.000
S41 Open wound of shoulder and upper arm	0.574	0.426	0.000
S40 Superficial injury of shoulder and upper arm	0.574	0.426	0.000
S47 Crushing injury of shoulder and upper arm	0.574	0.426	0.000
B48 Other mycoses, not elsewhere classified	0.572	0.428	0.000
B47 Mycetoma	0.572	0.428	0.000
B46 Zygomycosis	0.572	0.428	0.000
B45 Cryptococcosis	0.572	0.428	0.000
B44 Aspergillosis	0.572	0.428	0.000
B43 Chromomycosis and phaeomycotic abscess	0.572	0.428	0.000
B42 Sporotrichosis	0.572	0.428	0.000
B41 Paracoccidioidomycosis	0.572	0.428	0.000
B40 Blastomycosis	0.572	0.428	0.000
B39 Histoplasmosis	0.572	0.428	0.000
B38 Coccidioidomycosis	0.572	0.428	0.000
B36 Other superficial mycoses	0.572	0.428	0.000
B35 Dermatophytosis	0.572	0.428	0.000
B49 Unspecified mycosis	0.572	0.428	0.000
S63.6 Sprain and strain of finger(s)	0.571	0.429	0.000
S83.2 Tear of meniscus, current	0.571	0.429	0.000
I67 Other cerebrovascular diseases	0.570	0.430	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.569	0.431	0.000
S90 Superficial injury of ankle and foot	0.569	0.431	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.569	0.431	0.000
M66 Spontaneous rupture of synovium and tendon	0.569	0.431	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.567	0.433	0.000
I63.8 Other cerebral infarction	0.566	0.434	0.000
N61 Inflammatory disorders of breast	0.565	0.434	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.565	0.435	0.000
I27 Other pulmonary heart diseases	0.565	0.435	0.000
H55-H59 Other disorders of eye and adnexa	0.564	0.436	0.000
S89 Other and unspecified injuries of lower leg	0.564	0.436	0.000
N20.0 Calculus of kidney	0.564	0.436	0.000
M89 Other disorders of bone	0.564	0.436	0.000
S80 Superficial injury of lower leg	0.564	0.436	0.000
M31.6 Other giant cell arteritis	0.563	0.437	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.562	0.438	0.000
S37 Injury of urinary and pelvic organs	0.562	0.438	0.000
S36 Injury of intra-abdominal organs	0.562	0.438	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.562	0.438	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.562	0.438	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.562	0.438	0.000
S31 Open wound of abdomen, lower back and pelvis	0.562	0.438	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.560	0.440	0.000
S92 Fracture of foot, except ankle	0.560	0.440	0.000
N42.8 Other specified disorders of prostate	0.559	0.440	0.000
S88 Traumatic amputation of lower leg	0.559	0.441	0.000
S87 Crushing injury of lower leg	0.559	0.441	0.000
S86 Injury of muscle and tendon at lower leg level	0.559	0.441	0.000
S85 Injury of blood vessels at lower leg level	0.559	0.441	0.000
S84 Injury of nerves at lower leg level	0.559	0.441	0.000
S81 Open wound of lower leg	0.559	0.441	0.000
M47.8 Other spondylosis	0.559	0.441	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.559	0.441	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.559	0.441	0.000
T46.7 Peripheral vasodilators	0.559	0.441	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.559	0.441	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.559	0.441	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.559	0.441	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.559	0.441	0.000
T46.1 Calcium-channel blockers	0.559	0.441	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.559	0.441	0.000
N28.8 Other specified disorders of kidney and ureter	0.558	0.442	0.000
M21.1 Varus deformity, not elsewhere classified	0.558	0.442	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.557	0.443	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.557	0.443	0.000
Q80-Q89 Other congenital malformations	0.557	0.443	0.000
Q60-Q64 Congenital malformations of the urinary system	0.557	0.443	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.557	0.443	0.000
Q35-Q37 Cleft lip and cleft palate	0.557	0.443	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.557	0.443	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.557	0.443	0.000
Q00-Q07 Congenital malformations of the nervous system	0.557	0.443	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.556	0.444	0.000
T98 Sequelae of other and unspecified effects of external causes	0.556	0.444	0.000
T95 Sequelae of burns, corrosions and frostbite	0.556	0.444	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.556	0.444	0.000
T92 Sequelae of injuries of upper limb	0.556	0.444	0.000
T91 Sequelae of injuries of neck and trunk	0.556	0.444	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.556	0.444	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.556	0.444	0.000
S62.6 Fracture of other finger	0.553	0.447	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.552	0.448	0.000
I62 Other nontraumatic intracranial haemorrhage	0.550	0.450	0.000
S42.2 Fracture of upper end of humerus	0.550	0.450	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.550	0.450	0.000
M99 Biomechanical lesions, not elsewhere classified	0.549	0.450	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.549	0.450	0.000
M25.79 Osteophyte (Site unspecified)	0.549	0.451	0.000
M25.78 Osteophyte (Other)	0.549	0.451	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.549	0.451	0.000
M25.73 Osteophyte (Forearm)	0.549	0.451	0.000
M25.72 Osteophyte (Upper arm)	0.549	0.451	0.000
M25.71 Osteophyte (Shoulder region)	0.549	0.451	0.000
M25.70 Osteophyte (Multiple sites)	0.549	0.451	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.549	0.451	0.000
M21.3 Wrist or foot drop (acquired)	0.548	0.451	0.000
M65.3 Trigger finger	0.548	0.451	0.000
B37.9 Candidiasis, unspecified	0.548	0.452	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.548	0.452	0.000
B06 Rubella [German measles]	0.548	0.452	0.000
B05 Measles	0.548	0.452	0.000
B01 Varicella [chickenpox]	0.548	0.452	0.000
B00 Herpesviral [herpes simplex] infections	0.548	0.452	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.548	0.452	0.000
B04 Monkeypox	0.548	0.452	0.000
B03 Smallpox	0.548	0.452	0.000
I77 Other disorders of arteries and arterioles	0.548	0.452	0.000
I20.8 Other forms of angina pectoris	0.548	0.452	0.000
I20.9 Angina pectoris, unspecified	0.547	0.453	0.000
N02.9 Unspecified	0.547	0.453	0.000
Y86 Sequelae of other accidents	0.546	0.454	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.546	0.454	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.545	0.455	0.000
T65 Toxic effect of other and unspecified substances	0.545	0.455	0.000
T63 Toxic effect of contact with venomous animals	0.545	0.455	0.000
T62 Toxic effect of other noxious substances eaten as food	0.545	0.455	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.545	0.455	0.000
T60 Toxic effect of pesticides	0.545	0.455	0.000
T59 Toxic effect of other gases, fumes and vapours	0.545	0.455	0.000
T57 Toxic effect of other inorganic substances	0.545	0.455	0.000
T56 Toxic effect of metals	0.545	0.455	0.000
T54 Toxic effect of corrosive substances	0.545	0.455	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.545	0.455	0.000
T52 Toxic effect of organic solvents	0.545	0.455	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.545	0.455	0.000
T58 Toxic effect of carbon monoxide	0.545	0.455	0.000
T55 Toxic effect of soaps and detergents	0.545	0.455	0.000
M47.1 Other spondylosis with myelopathy	0.545	0.455	0.000
S42.4 Fracture of lower end of humerus	0.544	0.456	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.543	0.456	0.000
N27 Small kidney of unknown cause	0.543	0.456	0.000
N25 Disorders resulting from impaired renal tubular function	0.543	0.456	0.000
N26 Unspecified contracted kidney	0.543	0.456	0.000
I22.8 Subsequent myocardial infarction of other sites	0.543	0.457	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.543	0.457	0.000
H43-H45 Disorders of vitreous body and globe	0.543	0.457	0.000
S82 Fracture of lower leg, including ankle	0.542	0.458	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.540	0.460	0.000
M35.8 Other specified systemic involvement of connective tissue	0.540	0.460	0.000
M35.7 Hypermobility syndrome	0.540	0.460	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.540	0.460	0.000
M35.5 Multifocal fibrosclerosis	0.540	0.460	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.540	0.460	0.000
M35.2 Behcet's disease	0.540	0.460	0.000
M35.1 Other overlap syndromes	0.540	0.460	0.000
M21.9 Acquired deformity of limb, unspecified	0.540	0.460	0.000
M21.8 Other specified acquired deformities of limbs	0.540	0.460	0.000
M21.7 Unequal limb length (acquired)	0.540	0.460	0.000
M21.6 Other acquired deformities of ankle and foot	0.540	0.460	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.540	0.460	0.000
M21.4 Flat foot [pes planus] (acquired)	0.540	0.460	0.000
M21.2 Flexion deformity	0.540	0.460	0.000
W22 Striking against or struck by other objects	0.539	0.461	0.000
S00-S09 Injuries to the head	0.538	0.462	0.000
A30-A49 Other bacterial diseases	0.537	0.462	0.001
M24.9 Joint derangement, unspecified	0.538	0.462	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations