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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75655068
log Bayes Factor = 13.5772
Chromosome 7   position 92,658,364  (GRCh37) Explore rs75655068 on Ensembl!
Variant rs75655068 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
M15-M19 Arthrosis
0.997 0.003 0.000
K22 Other diseases of oesophagus
0.996 0.004 0.000
K31 Other diseases of stomach and duodenum
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
M16 Coxarthrosis [arthrosis of hip]
0.989 0.011 0.000
K31.8 Other specified diseases of stomach and duodenum
0.984 0.016 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.984 0.016 0.000
S60-S69 Injuries to the wrist and hand
0.981 0.019 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
K22.1 Ulcer of oesophagus
0.974 0.026 0.000
M45-M49 Spondylopathies
0.973 0.027 0.000
M70-M79 Other soft tissue disorders
0.972 0.028 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.963 0.037 0.000
S80-S89 Injuries to the knee and lower leg
0.963 0.037 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.950 0.050 0.000
K26 Duodenal ulcer
0.950 0.050 0.000
M47 Spondylosis
0.950 0.050 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.948 0.052 0.000
M16.9 Coxarthrosis, unspecified
0.946 0.054 0.000
M75 Shoulder lesions
0.944 0.056 0.000
D00-D09 In situ neoplasms
0.938 0.062 0.000
M20-M25 Other joint disorders
0.935 0.065 0.000
K22.8 Other specified diseases of oesophagus
0.932 0.068 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.930 0.070 0.000
D50-D53 Nutritional anaemias
0.921 0.079 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.921 0.079 0.000
M16.1 Other primary coxarthrosis
0.920 0.080 0.000
K22.2 Oesophageal obstruction
0.919 0.081 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.917 0.083 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.914 0.086 0.000
M47.8 Other spondylosis
0.910 0.090 0.000
S61 Open wound of wrist and hand
0.908 0.092 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.904 0.096 0.000
O42 Premature rupture of membranes
0.900 0.100 0.000
C79 Secondary malignant neoplasm of other sites
0.900 0.100 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.899 0.101 0.000
M17 Gonarthrosis [arthrosis of knee]
0.896 0.104 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.894 0.106 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.894 0.106 0.000
S62 Fracture at wrist and hand level
0.893 0.107 0.000
R06 Abnormalities of breathing
0.892 0.108 0.000
R06.0 Dyspnoea
0.891 0.109 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.890 0.110 0.000
M75.1 Rotator cuff syndrome
0.888 0.112 0.000
D10-D36 Benign neoplasms
0.886 0.114 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.885 0.115 0.000
K20 Oesophagitis
0.884 0.116 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.880 0.120 0.000
D50 Iron deficiency anaemia
0.878 0.122 0.000
O20 Haemorrhage in early pregnancy
0.878 0.122 0.000
K70-K77 Diseases of liver
0.875 0.125 0.000
M17.1 Other primary gonarthrosis
0.875 0.125 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.868 0.132 0.000
M18 Arthrosis of first carpometacarpal joint
0.868 0.132 0.000
K35-K38 Diseases of appendix
0.863 0.137 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.860 0.140 0.000
G40-G47 Episodic and paroxysmal disorders
0.858 0.142 0.000
C34 Malignant neoplasm of bronchus and lung
0.852 0.148 0.000
Chapter XX External causes of morbidity and mortality
0.851 0.149 0.000
D23 Other benign neoplasms of skin
0.850 0.150 0.000
M23 Internal derangement of knee
0.850 0.150 0.000
Chapter I Certain infectious and parasitic diseases
0.848 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.848 0.152 0.000
S61.0 Open wound of finger(s) without damage to nail
0.847 0.153 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.845 0.155 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.842 0.158 0.000
D50.9 Iron deficiency anaemia, unspecified
0.842 0.158 0.000
M35 Other systemic involvement of connective tissue
0.837 0.163 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.837 0.163 0.000
K25 Gastric ulcer
0.836 0.164 0.000
M65-M68 Disorders of synovium and tendon
0.834 0.166 0.000
C77.8 Lymph nodes of multiple regions
0.833 0.167 0.000
S20-S29 Injuries to the thorax
0.830 0.170 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.828 0.172 0.000
M47.9 Spondylosis, unspecified
0.828 0.172 0.000
Chapter V Mental and behavioural disorders
0.828 0.172 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.828 0.172 0.000
C83.3 Large cell (diffuse)
0.826 0.173 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.825 0.175 0.000
D05 Carcinoma in situ of breast
0.824 0.176 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.822 0.178 0.000
K26.4 Chronic or unspecified with haemorrhage
0.820 0.180 0.000
A30-A49 Other bacterial diseases
0.820 0.180 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.819 0.181 0.000
S81 Open wound of lower leg
0.818 0.182 0.000
O16 Unspecified maternal hypertension
0.816 0.184 0.000
S50-S59 Injuries to the elbow and forearm
0.816 0.184 0.000
D23.6 Skin of upper limb, including shoulder
0.816 0.184 0.000
S82 Fracture of lower leg, including ankle
0.815 0.185 0.000
G90-G99 Other disorders of the nervous system
0.811 0.189 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.811 0.189 0.000
M75.0 Adhesive capsulitis of shoulder
0.807 0.193 0.000
O42.9 Premature rupture of membranes, unspecified
0.807 0.193 0.000
M16.3 Other dysplastic coxarthrosis
0.804 0.196 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.802 0.198 0.000
M47.86 Other spondylosis (Lumbar region)
0.802 0.198 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.801 0.199 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.800 0.200 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.799 0.201 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.797 0.203 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.797 0.203 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.795 0.205 0.000
M45 Ankylosing spondylitis
0.793 0.207 0.000
D70 Agranulocytosis
0.793 0.207 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.792 0.208 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.792 0.208 0.000
T43.2 Other and unspecified antidepressants
0.791 0.209 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.791 0.209 0.000
M75.4 Impingement syndrome of shoulder
0.789 0.211 0.000
Chapter X Diseases of the respiratory system
0.788 0.212 0.000
O36 Maternal care for other known or suspected foetal problems
0.786 0.214 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.786 0.214 0.000
M25 Other joint disorders, not elsewhere classified
0.784 0.216 0.000
C78.7 Secondary malignant neoplasm of liver
0.779 0.221 0.000
M86-M90 Other osteopathies
0.778 0.222 0.000
R04 Haemorrhage from respiratory passages
0.778 0.222 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.776 0.224 0.000
D06 Carcinoma in situ of cervix uteri
0.776 0.224 0.000
T42.4 Benzodiazepines
0.774 0.226 0.000
M16.0 Primary coxarthrosis, bilateral
0.771 0.229 0.000
M35.3 Polymyalgia rheumatica
0.769 0.231 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.768 0.232 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.767 0.233 0.000
O80-O84 Delivery
0.766 0.234 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.766 0.234 0.000
D51 Vitamin B12 deficiency anaemia
0.764 0.236 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.763 0.237 0.000
C77.2 Intra-abdominal lymph nodes
0.763 0.237 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.762 0.238 0.000
D25 Leiomyoma of uterus
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.760 0.239 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.761 0.239 0.000
K36 Other appendicitis
0.760 0.240 0.000
C34.1 Upper lobe, bronchus or lung
0.760 0.240 0.000
O24 Diabetes mellitus in pregnancy
0.760 0.240 0.000
S62.3 Fracture of other metacarpal bone
0.759 0.241 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.759 0.241 0.000
D03 Melanoma in situ
0.758 0.242 0.000
K70 Alcoholic liver disease
0.757 0.243 0.000
A41 Other septicaemia
0.757 0.243 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.757 0.243 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.756 0.244 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.755 0.245 0.000
D48.1 Connective and other soft tissue
0.755 0.245 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.754 0.246 0.000
W00-W19 Falls
0.754 0.246 0.000
K26.5 Chronic or unspecified with perforation
0.753 0.247 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.247 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
M80-M85 Disorders of bone density and structure
0.751 0.249 0.000
K31.5 Obstruction of duodenum
0.750 0.250 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.749 0.251 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.749 0.251 0.000
M21 Other acquired deformities of limbs
0.748 0.252 0.000
D60-D64 Aplastic and other anaemias
0.747 0.253 0.000
J90-J94 Other diseases of pleura
0.744 0.256 0.000
C34.9 Bronchus or lung, unspecified
0.743 0.257 0.000
C78.0 Secondary malignant neoplasm of lung
0.743 0.257 0.000
S60 Superficial injury of wrist and hand
0.742 0.258 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.742 0.258 0.000
M46 Other inflammatory spondylopathies
0.741 0.259 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.740 0.260 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.740 0.260 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.739 0.261 0.000
C77.9 Lymph node, unspecified
0.739 0.261 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.739 0.261 0.000
K22.7 Barrett's oesophagus
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.738 0.261 0.000
K26.3 Acute without haemorrhage or perforation
0.738 0.262 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.738 0.262 0.000
M75.2 Bicipital tendinitis
0.738 0.262 0.000
D16 Benign neoplasm of bone and articular cartilage
0.738 0.262 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.737 0.263 0.000
K22.4 Dyskinesia of oesophagus
0.735 0.265 0.000
K76 Other diseases of liver
0.734 0.266 0.000
M76 Enthesopathies of lower limb, excluding foot
0.732 0.268 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.731 0.269 0.000
T51 Toxic effect of alcohol
0.731 0.269 0.000
O20.8 Other haemorrhage in early pregnancy
0.731 0.269 0.000
D50.8 Other iron deficiency anaemias
0.730 0.270 0.000
M91-M94 Chondropathies
0.730 0.270 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.730 0.270 0.000
D09 Carcinoma in situ of other and unspecified sites
0.727 0.273 0.000
D48.0 Bone and articular cartilage
0.725 0.275 0.000
R04.0 Epistaxis
0.724 0.276 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.722 0.278 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.722 0.278 0.000
D25.1 Intramural leiomyoma of uterus
0.722 0.278 0.000
C88 Malignant immunoproliferative diseases
0.722 0.278 0.000
A41.9 Septicaemia, unspecified
0.721 0.279 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.721 0.279 0.000
S61.1 Open wound of finger(s) with damage to nail
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
D48.7 Other specified sites
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.716 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.716 0.283 0.000
F41 Other anxiety disorders
0.716 0.284 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.716 0.284 0.000
M47.1 Other spondylosis with myelopathy
0.715 0.285 0.000
M15 Polyarthrosis
0.715 0.285 0.000
D23.5 Skin of trunk
0.714 0.286 0.000
K22.5 Diverticulum of oesophagus, acquired
0.714 0.286 0.000
K22.3 Perforation of oesophagus
0.714 0.286 0.000
G93 Other disorders of brain
0.713 0.287 0.000
K31.6 Fistula of stomach and duodenum
0.712 0.288 0.000
K31.4 Gastric diverticulum
0.712 0.288 0.000
K31.3 Pylorospasm, not elsewhere classified
0.712 0.288 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.712 0.288 0.000
K31.0 Acute dilatation of stomach
0.712 0.288 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
J90 Pleural effusion, not elsewhere classified
0.711 0.289 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.711 0.289 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.711 0.289 0.000
S80 Superficial injury of lower leg
0.711 0.289 0.000
M17.5 Other secondary gonarthrosis
0.710 0.290 0.000
M16.7 Other secondary coxarthrosis
0.709 0.291 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.709 0.291 0.000
M16.5 Other posttraumatic coxarthrosis
0.709 0.291 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.709 0.291 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.709 0.291 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.709 0.291 0.000
A49 Bacterial infection of unspecified site
0.709 0.291 0.000
Q80-Q89 Other congenital malformations
0.708 0.292 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.707 0.293 0.000
M77 Other enthesopathies
0.707 0.293 0.000
D23.4 Skin of scalp and neck
0.707 0.293 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.707 0.293 0.000
D05.1 Intraductal carcinoma in situ
0.706 0.294 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.705 0.294 0.000
R47-R49 Symptoms and signs involving speech and voice
0.705 0.295 0.000
K25.3 Acute without haemorrhage or perforation
0.704 0.295 0.000
S62.6 Fracture of other finger
0.704 0.296 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.704 0.296 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.703 0.297 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.703 0.297 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.703 0.297 0.000
C79.6 Secondary malignant neoplasm of ovary
0.702 0.298 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.702 0.298 0.000
S83.2 Tear of meniscus, current
0.702 0.298 0.000
D35.2 Pituitary gland
0.701 0.298 0.000
K22.0 Achalasia of cardia
0.701 0.299 0.000
S62.4 Multiple fractures of metacarpal bones
0.700 0.300 0.000
M23.4 Loose body in knee
0.700 0.300 0.000
C77.0 Lymph nodes of head, face and neck
0.699 0.301 0.000
C77.1 Intrathoracic lymph nodes
0.698 0.302 0.000
Y43 Primarily systemic agents
0.698 0.302 0.000
S62.5 Fracture of thumb
0.698 0.302 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.698 0.302 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.698 0.302 0.000
Chapter XXII Codes for special purposes
0.698 0.302 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.302 0.000
O41 Other disorders of amniotic fluid and membranes
0.697 0.303 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.697 0.303 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.697 0.303 0.000
M71 Other bursopathies
0.697 0.303 0.000
D26 Other benign neoplasms of uterus
0.697 0.303 0.000
K90-K93 Other diseases of the digestive system
0.696 0.304 0.000
S68 Traumatic amputation of wrist and hand
0.695 0.305 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.695 0.305 0.000
R06.4 Hyperventilation
0.694 0.306 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.694 0.306 0.000
K26.7 Chronic without haemorrhage or perforation
0.694 0.306 0.000
M75.3 Calcific tendinitis of shoulder
0.694 0.306 0.000
S82.8 Fractures of other parts of lower leg
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
S67 Crushing injury of wrist and hand
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.308 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.309 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.691 0.309 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.691 0.309 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.691 0.309 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.691 0.309 0.000
D55-D59 Haemolytic anaemias
0.690 0.309 0.000
S88 Traumatic amputation of lower leg
0.690 0.310 0.000
S87 Crushing injury of lower leg
0.690 0.310 0.000
S86 Injury of muscle and tendon at lower leg level
0.690 0.310 0.000
S85 Injury of blood vessels at lower leg level
0.690 0.310 0.000
S84 Injury of nerves at lower leg level
0.690 0.310 0.000
J20-J22 Other acute lower respiratory infections
0.688 0.311 0.000
F30-F39 Mood [affective] disorders
0.688 0.312 0.000
S27 Injury of other and unspecified intrathoracic organs
0.687 0.313 0.000
K76.8 Other specified diseases of liver
0.687 0.313 0.000
S82.4 Fracture of fibula alone
0.685 0.315 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.685 0.315 0.000
G47 Sleep disorders
0.685 0.315 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.318 0.000
O29 Complications of anaesthesia during pregnancy
0.681 0.318 0.000
O28 Abnormal findings on antenatal screening of mother
0.681 0.318 0.000
O23 Infections of genito-urinary tract in pregnancy
0.681 0.318 0.000
O22 Venous complications in pregnancy
0.681 0.318 0.000
O21 Excessive vomiting in pregnancy
0.681 0.318 0.000
O25 Malnutrition in pregnancy
0.681 0.318 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.681 0.318 0.000
K26.2 Acute with both haemorrhage and perforation
0.681 0.318 0.000
K26.1 Acute with perforation
0.681 0.318 0.000
K26.0 Acute with haemorrhage
0.681 0.318 0.000
O36.9 Maternal care for foetal problem, unspecified
0.681 0.319 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.681 0.319 0.000
S69 Other and unspecified injuries of wrist and hand
0.681 0.319 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.681 0.319 0.000
O45 Premature separation of placenta [abruptio placentae]
0.680 0.320 0.000
O44 Placenta praevia
0.680 0.320 0.000
O43 Placental disorders
0.680 0.320 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.680 0.320 0.000
O33 Maternal care for known or suspected disproportion
0.680 0.320 0.000
O31 Complications specific to multiple gestation
0.680 0.320 0.000
O40 Polyhydramnios
0.680 0.320 0.000
S89 Other and unspecified injuries of lower leg
0.679 0.321 0.000
K75 Other inflammatory liver diseases
0.679 0.321 0.000
S70-S79 Injuries to the hip and thigh
0.679 0.321 0.000
K70.0 Alcoholic fatty liver
0.679 0.321 0.000
D62 Acute posthaemorrhagic anaemia
0.678 0.322 0.000
M75.8 Other shoulder lesions
0.677 0.323 0.000
M75.9 Shoulder lesion, unspecified
0.677 0.323 0.000
M66 Spontaneous rupture of synovium and tendon
0.677 0.323 0.000
D29 Benign neoplasm of male genital organs
0.676 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.675 0.325 0.000
K50-K52 Noninfective enteritis and colitis
0.675 0.325 0.000
D37.7 Other digestive organs
0.675 0.325 0.000
G96 Other disorders of central nervous system
0.674 0.326 0.000
S82.2 Fracture of shaft of tibia
0.674 0.326 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.673 0.327 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.673 0.327 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.673 0.327 0.000
T40.2 Other opioids
0.673 0.327 0.000
D05.0 Lobular carcinoma in situ
0.671 0.329 0.000
K31.7 Polyp of stomach and duodenum
0.671 0.329 0.000
M47.2 Other spondylosis with radiculopathy
0.671 0.329 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.670 0.330 0.000
M34 Systemic sclerosis
0.670 0.330 0.000
M33 Dermatopolymyositis
0.670 0.330 0.000
M32 Systemic lupus erythematosus
0.670 0.330 0.000
M30 Polyarteritis nodosa and related conditions
0.670 0.330 0.000
D36 Benign neoplasm of other and unspecified sites
0.670 0.330 0.000
J95-J99 Other diseases of the respiratory system
0.670 0.330 0.000
R06.6 Hiccough
0.669 0.331 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.667 0.332 0.000
C95 Leukaemia of unspecified cell type
0.667 0.332 0.000
C94 Other leukaemias of specified cell type
0.667 0.332 0.000
C93 Monocytic leukaemia
0.667 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.667 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.667 0.332 0.000
S64 Injury of nerves at wrist and hand level
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
F41.9 Anxiety disorder, unspecified
0.667 0.333 0.000
M40-M43 Deforming dorsopathies
0.667 0.333 0.000
C85.1 B-cell lymphoma, unspecified
0.665 0.335 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.665 0.335 0.000
C77.4 Inguinal and lower limb lymph nodes
0.665 0.335 0.000
K86 Other diseases of pancreas
0.664 0.336 0.000
S00-S09 Injuries to the head
0.663 0.337 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.663 0.337 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.663 0.337 0.000
D35.0 Adrenal gland
0.663 0.337 0.000
M72 Fibroblastic disorders
0.662 0.338 0.000
S50 Superficial injury of forearm
0.661 0.339 0.000
S81.9 Open wound of lower leg, part unspecified
0.661 0.339 0.000
D53 Other nutritional anaemias
0.660 0.340 0.000
T43.9 Psychotropic drug, unspecified
0.660 0.340 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
T43.6 Psychostimulants with abuse potential
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.660 0.340 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.660 0.340 0.000
A40 Streptococcal septicaemia
0.660 0.340 0.000
R06.2 Wheezing
0.659 0.341 0.000
D06.9 Cervix, unspecified
0.659 0.341 0.000
Q28 Other congenital malformations of circulatory system
0.659 0.341 0.000
D23.2 Skin of ear and external auricular canal
0.659 0.341 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.658 0.342 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.657 0.342 0.000
Y43.3 Other antineoplastic drugs
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.656 0.344 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.655 0.345 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.655 0.345 0.000
C32 Malignant neoplasm of larynx
0.655 0.345 0.000
C31 Malignant neoplasm of accessory sinuses
0.655 0.345 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.655 0.345 0.000
C37 Malignant neoplasm of thymus
0.655 0.345 0.000
C33 Malignant neoplasm of trachea
0.655 0.345 0.000
R07 Pain in throat and chest
0.654 0.346 0.000
K25.7 Chronic without haemorrhage or perforation
0.654 0.346 0.000
C79.2 Secondary malignant neoplasm of skin
0.653 0.347 0.000
M47.89 Other spondylosis (Site unspecified)
0.653 0.347 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.653 0.347 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.653 0.347 0.000
M47.84 Other spondylosis (Thoracic region)
0.653 0.347 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.653 0.347 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.653 0.347 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.653 0.347 0.000
G30-G32 Other degenerative diseases of the nervous system
0.652 0.348 0.000
Q21 Congenital malformations of cardiac septa
0.652 0.348 0.000
S61.7 Multiple open wounds of wrist and hand
0.651 0.349 0.000
D46 Myelodysplastic syndromes
0.649 0.351 0.000
D37.5 Rectum
0.649 0.351 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.351 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.351 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.351 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.648 0.351 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.648 0.352 0.000
K38 Other diseases of appendix
0.648 0.352 0.000
X60-X84 Intentional self-harm
0.648 0.352 0.000
D23.3 Skin of other and unspecified parts of face
0.648 0.352 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.647 0.352 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.647 0.353 0.000
T51.0 Ethanol
0.647 0.353 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.645 0.355 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.645 0.355 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.645 0.355 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.645 0.355 0.000
G93.8 Other specified disorders of brain
0.645 0.355 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.645 0.355 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.645 0.355 0.000
S81.8 Open wound of other parts of lower leg
0.645 0.355 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.645 0.355 0.000
G45.3 Amaurosis fugax
0.644 0.355 0.000
M65 Synovitis and tenosynovitis
0.644 0.356 0.000
B15-B19 Viral hepatitis
0.644 0.356 0.000
F60-F69 Disorders of adult personality and behaviour
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.643 0.356 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.643 0.357 0.000
C81 Hodgkin's disease
0.642 0.358 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.642 0.358 0.000
M17.3 Other posttraumatic gonarthrosis
0.642 0.358 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.642 0.358 0.000
O15 Eclampsia
0.641 0.359 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.641 0.359 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.641 0.359 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.641 0.359 0.000
S62.7 Multiple fractures of fingers
0.640 0.359 0.000
S62.2 Fracture of first metacarpal bone
0.640 0.359 0.000
S62.1 Fracture of other carpal bone(s)
0.640 0.359 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.640 0.359 0.000
R06.7 Sneezing
0.639 0.360 0.000
R06.3 Periodic breathing
0.639 0.360 0.000
R06.1 Stridor
0.639 0.360 0.000
O46.9 Antepartum haemorrhage, unspecified
0.639 0.361 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.639 0.361 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.639 0.361 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.638 0.362 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.638 0.362 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.638 0.362 0.000
T42.3 Barbiturates
0.638 0.362 0.000
T42.2 Succinimides and oxazolidinediones
0.638 0.362 0.000
T42.1 Iminostilbenes
0.638 0.362 0.000
T42.0 Hydantoin derivatives
0.638 0.362 0.000
D10 Benign neoplasm of mouth and pharynx
0.638 0.362 0.000
A49.8 Other bacterial infections of unspecified site
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.637 0.363 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.637 0.363 0.000
D37.1 Stomach
0.637 0.363 0.000
O26.8 Other specified pregnancy-related conditions
0.636 0.364 0.000
M47.82 Other spondylosis (Cervical region)
0.636 0.364 0.000
O36.4 Maternal care for intra-uterine death
0.636 0.364 0.000
D31 Benign neoplasm of eye and adnexa
0.635 0.364 0.000
D30 Benign neoplasm of urinary organs
0.635 0.364 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.635 0.364 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.635 0.364 0.000
D19 Benign neoplasm of mesothelial tissue
0.635 0.364 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.635 0.364 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.635 0.365 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.635 0.365 0.000
W20-W49 Exposure to inanimate mechanical forces
0.635 0.365 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.635 0.365 0.000
D48.6 Breast
0.635 0.365 0.000
D48.5 Skin
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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