TreeWAS – Variant ID: rs7572554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.000	1.000
I83 Varicose veins of lower extremities	0.000	0.331	0.669
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.362	0.638
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.533	0.467
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.713	0.287
F17.2 Dependence syndrome	0.117	0.883	0.000
I69.3 Sequelae of cerebral infarction	0.082	0.918	0.000
I69 Sequelae of cerebrovascular disease	0.069	0.931	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.064	0.936	0.000
I61 Intracerebral haemorrhage	0.063	0.937	0.000
I60-I69 Cerebrovascular diseases	0.062	0.938	0.000
I60 Subarachnoid haemorrhage	0.060	0.940	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.059	0.941	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.054	0.946	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.053	0.947	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.053	0.947	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.053	0.947	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.053	0.947	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.052	0.948	0.000
I63 Cerebral infarction	0.052	0.948	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.052	0.948	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.052	0.948	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.049	0.951	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.049	0.951	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.047	0.953	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.046	0.954	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.046	0.954	0.000
I61.8 Other intracerebral haemorrhage	0.046	0.954	0.000
I60.8 Other subarachnoid haemorrhage	0.046	0.954	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.045	0.955	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.044	0.956	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.044	0.956	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.043	0.957	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.042	0.958	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.042	0.958	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.042	0.958	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.041	0.959	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.040	0.960	0.000
F17.9 Unspecified mental and behavioural disorder	0.040	0.960	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.040	0.960	0.000
F17.8 Other mental and behavioural disorders	0.038	0.961	0.000
F17.7 Residual and late-onset psychotic disorder	0.038	0.961	0.000
F17.6 Amnesic syndrome	0.038	0.961	0.000
F17.5 Psychotic disorder	0.038	0.961	0.000
F17.4 Withdrawal state with delirium	0.038	0.961	0.000
F17.3 Withdrawal state	0.038	0.961	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.037	0.962	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.037	0.962	0.000
I63.8 Other cerebral infarction	0.037	0.963	0.000
F17.1 Harmful use	0.037	0.963	0.000
F17.0 Acute intoxication	0.037	0.963	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.036	0.963	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.037	0.963	0.000
I68.0 Cerebral amyloid angiopathy	0.035	0.965	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.035	0.965	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.035	0.965	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.034	0.966	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.034	0.966	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.033	0.966	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.033	0.966	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.033	0.966	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.033	0.967	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.033	0.967	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.033	0.967	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.033	0.967	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.032	0.968	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.032	0.968	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.032	0.968	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.032	0.968	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.031	0.969	0.000
I67 Other cerebrovascular diseases	0.031	0.969	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.029	0.971	0.000
I63.9 Cerebral infarction, unspecified	0.029	0.971	0.000
I65.1 Occlusion and stenosis of basilar artery	0.028	0.972	0.000
I67.2 Cerebral atherosclerosis	0.027	0.973	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.027	0.973	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.026	0.974	0.000
I62 Other nontraumatic intracranial haemorrhage	0.025	0.975	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.023	0.977	0.000
I67.5 Moyamoya disease	0.023	0.977	0.000
I67.4 Hypertensive encephalopathy	0.023	0.977	0.000
I67.3 Progressive vascular leukoencephalopathy	0.023	0.977	0.000
I67.9 Cerebrovascular disease, unspecified	0.022	0.978	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.021	0.979	0.000
I65.2 Occlusion and stenosis of carotid artery	0.021	0.979	0.000
I62.1 Nontraumatic extradural haemorrhage	0.018	0.982	0.000
H54.0 Blindness, both eyes	0.000	0.985	0.015
S82.10 Fracture of upper end of tibia (closed)	0.013	0.987	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.012	0.987	0.000
H54 Blindness and low vision	0.000	0.988	0.012
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.011	0.989	0.000
I67.1 Cerebral aneurysm, nonruptured	0.011	0.989	0.000
H54.7 Unspecified visual loss	0.000	0.989	0.011
H54.9 Unspecified visual impairment (binocular)	0.000	0.990	0.010
C16.9 Stomach, unspecified	0.010	0.990	0.000
Z43.2 Attention to ileostomy	0.010	0.990	0.000
S82.1 Fracture of upper end of tibia	0.010	0.990	0.000
H54.2 Low vision, both eyes	0.000	0.990	0.010
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.010	0.990	0.000
S82.30 Fracture of lower end of tibia (closed)	0.010	0.990	0.000
S82.3 Fracture of lower end of tibia	0.010	0.990	0.000
S82.31 Fracture of lower end of tibia (open)	0.009	0.991	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.991	0.009
H54.1 Blindness, one eye, low vision, other eye	0.000	0.991	0.009
H54.5 Low vision, one eye	0.000	0.991	0.009
H54.6 Unqualified visual loss, one eye	0.000	0.991	0.009
H54.4 Blindness, one eye	0.000	0.992	0.008
F12 Mental and behavioural disorders due to use of cannabinoids	0.008	0.992	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.008	0.992	0.000
S82 Fracture of lower leg, including ankle	0.008	0.992	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.008	0.992	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.993	0.007
K86.1 Other chronic pancreatitis	0.007	0.993	0.000
F11 Mental and behavioural disorders due to use of opioids	0.007	0.993	0.000
Z57.2 Occupational exposure to dust	0.000	0.993	0.007
S82.11 Fracture of upper end of tibia (open)	0.007	0.993	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.007	0.993	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
S82.9 Fracture of lower leg, part unspecified	0.007	0.993	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.007	0.993	0.000
F14.2 Dependence syndrome	0.006	0.993	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.993	0.007
F12.1 Harmful use	0.006	0.993	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.006	0.994	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.006	0.994	0.000
S82.2 Fracture of shaft of tibia	0.006	0.994	0.000
C16.3 Pyloric antrum	0.006	0.994	0.000
C16.2 Body of stomach	0.006	0.994	0.000
F12.0 Acute intoxication	0.006	0.994	0.000
F12.2 Dependence syndrome	0.006	0.994	0.000
F14.1 Harmful use	0.006	0.994	0.000
C16.5 Lesser curvature of stomach, unspecified	0.006	0.994	0.000
S82.8 Fractures of other parts of lower leg	0.006	0.994	0.000
C16.6 Greater curvature of stomach, unspecified	0.006	0.994	0.000
F12.9 Unspecified mental and behavioural disorder	0.006	0.994	0.000
F12.8 Other mental and behavioural disorders	0.006	0.994	0.000
F12.7 Residual and late-onset psychotic disorder	0.006	0.994	0.000
F12.6 Amnesic syndrome	0.006	0.994	0.000
F12.5 Psychotic disorder	0.006	0.994	0.000
F12.4 Withdrawal state with delirium	0.006	0.994	0.000
F12.3 Withdrawal state	0.006	0.994	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.006	0.994	0.000
F14.9 Unspecified mental and behavioural disorder	0.006	0.994	0.000
F14.8 Other mental and behavioural disorders	0.006	0.994	0.000
F14.7 Residual and late-onset psychotic disorder	0.006	0.994	0.000
F14.6 Amnesic syndrome	0.006	0.994	0.000
F14.5 Psychotic disorder	0.006	0.994	0.000
F14.4 Withdrawal state with delirium	0.006	0.994	0.000
F14.3 Withdrawal state	0.006	0.994	0.000
F14.0 Acute intoxication	0.006	0.994	0.000
F11.1 Harmful use	0.006	0.994	0.000
I88 Nonspecific lymphadenitis	0.000	0.994	0.006
S82.0 Fracture of patella	0.006	0.994	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
C16.8 Overlapping lesion of stomach	0.006	0.994	0.000
F11.2 Dependence syndrome	0.005	0.994	0.000
F11.9 Unspecified mental and behavioural disorder	0.005	0.994	0.000
F11.8 Other mental and behavioural disorders	0.005	0.994	0.000
F11.7 Residual and late-onset psychotic disorder	0.005	0.994	0.000
F11.6 Amnesic syndrome	0.005	0.994	0.000
F11.5 Psychotic disorder	0.005	0.994	0.000
F11.4 Withdrawal state with delirium	0.005	0.994	0.000
F11.0 Acute intoxication	0.005	0.994	0.000
S82.81 Fractures of other parts of lower leg (open)	0.005	0.995	0.000
F16.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
F16.8 Other mental and behavioural disorders	0.005	0.995	0.000
F16.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F16.6 Amnesic syndrome	0.005	0.995	0.000
F16.5 Psychotic disorder	0.005	0.995	0.000
F16.4 Withdrawal state with delirium	0.005	0.995	0.000
F16.3 Withdrawal state	0.005	0.995	0.000
F16.2 Dependence syndrome	0.005	0.995	0.000
F16.1 Harmful use	0.005	0.995	0.000
F16.0 Acute intoxication	0.005	0.995	0.000
F18.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
F18.8 Other mental and behavioural disorders	0.005	0.995	0.000
F18.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F18.6 Amnesic syndrome	0.005	0.995	0.000
F18.5 Psychotic disorder	0.005	0.995	0.000
F18.4 Withdrawal state with delirium	0.005	0.995	0.000
F18.3 Withdrawal state	0.005	0.995	0.000
F18.2 Dependence syndrome	0.005	0.995	0.000
F18.1 Harmful use	0.005	0.995	0.000
F18.0 Acute intoxication	0.005	0.995	0.000
I86.8 Varicose veins of other specified sites	0.000	0.995	0.005
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.995	0.005
I86 Varicose veins of other sites	0.000	0.995	0.005
S82.21 Fracture of shaft of tibia (open)	0.005	0.995	0.000
F11.3 Withdrawal state	0.005	0.995	0.000
Z36.8 Other antenatal screening	0.000	0.995	0.005
C16.4 Pylorus	0.005	0.995	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.005	0.995	0.000
K86 Other diseases of pancreas	0.005	0.995	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.005	0.995	0.000
F13.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
F13.8 Other mental and behavioural disorders	0.005	0.995	0.000
F13.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F13.6 Amnesic syndrome	0.005	0.995	0.000
F13.5 Psychotic disorder	0.005	0.995	0.000
F13.4 Withdrawal state with delirium	0.005	0.995	0.000
F13.3 Withdrawal state	0.005	0.995	0.000
F13.1 Harmful use	0.005	0.995	0.000
F13.0 Acute intoxication	0.005	0.995	0.000
F15.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
F15.8 Other mental and behavioural disorders	0.005	0.995	0.000
F15.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F15.6 Amnesic syndrome	0.005	0.995	0.000
F15.5 Psychotic disorder	0.005	0.995	0.000
F15.4 Withdrawal state with delirium	0.005	0.995	0.000
F15.3 Withdrawal state	0.005	0.995	0.000
F15.2 Dependence syndrome	0.005	0.995	0.000
F15.0 Acute intoxication	0.005	0.995	0.000
F19.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
F19.8 Other mental and behavioural disorders	0.005	0.995	0.000
F19.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
F19.6 Amnesic syndrome	0.005	0.995	0.000
F19.5 Psychotic disorder	0.005	0.995	0.000
F19.4 Withdrawal state with delirium	0.005	0.995	0.000
F19.3 Withdrawal state	0.005	0.995	0.000
F19.0 Acute intoxication	0.005	0.995	0.000
I67.8 Other specified cerebrovascular diseases	0.005	0.995	0.000
S82.7 Multiple fractures of lower leg	0.005	0.995	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.995	0.005
Z72.0 Tobacco use	0.005	0.995	0.000
S82.20 Fracture of shaft of tibia (closed)	0.005	0.995	0.000
Z50.5 Speech therapy	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.995	0.005
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.995	0.005
C50.8 Overlapping lesion of breast	0.005	0.995	0.000
K86.8 Other specified diseases of pancreas	0.005	0.995	0.000
F19.1 Harmful use	0.004	0.995	0.000
K86.2 Cyst of pancreas	0.005	0.995	0.000
S82.86 Maisonneuve's fracture	0.004	0.995	0.000
S82.01 Fracture of patella (open)	0.004	0.995	0.000
Z01.6 Radiological examination, not elsewhere classified	0.005	0.995	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.995	0.004
F13.2 Dependence syndrome	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
F19.2 Dependence syndrome	0.004	0.996	0.000
K86.3 Pseudocyst of pancreas	0.004	0.996	0.000
I86.2 Pelvic varices	0.000	0.996	0.004
C16.1 Fundus of stomach	0.004	0.996	0.000
S82.5 Fracture of medial malleolus	0.004	0.996	0.000
I88.8 Other nonspecific lymphadenitis	0.000	0.996	0.004
I86.3 Vulval varices	0.000	0.996	0.004
S82.6 Fracture of lateral malleolus	0.004	0.996	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.996	0.004
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
I49.5 Sick sinus syndrome	0.000	0.996	0.004
F15.1 Harmful use	0.004	0.996	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.996	0.004
I86.0 Sublingual varices	0.000	0.996	0.004
S06.6 Traumatic subarachnoid haemorrhage	0.004	0.996	0.000
S82.4 Fracture of fibula alone	0.004	0.996	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
S82.71 Multiple fractures of lower leg (open)	0.003	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.004	0.996	0.000
C71.2 Temporal lobe	0.004	0.996	0.000
I87 Other disorders of veins	0.000	0.996	0.003
S82.61 Fracture of lateral malleolus (open)	0.003	0.996	0.000
I81 Portal vein thrombosis	0.000	0.997	0.003
C16.0 Cardia	0.003	0.997	0.000
I89.1 Lymphangitis	0.000	0.997	0.003
S82.51 Fracture of medial malleolus (open)	0.003	0.997	0.000
G71.0 Muscular dystrophy	0.000	0.997	0.003
S06 Intracranial injury	0.003	0.997	0.000
N80.8 Other endometriosis	0.003	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.997	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.003	0.997	0.000
I85 Oesophageal varices	0.000	0.997	0.003
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
S82.41 Fracture of fibula alone (open)	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
S06.0 Concussion	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.003	0.997	0.000
I86.1 Scrotal varices	0.000	0.997	0.003
R27.0 Ataxia, unspecified	0.003	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.997	0.000
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.997	0.003
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
B37.0 Candidal stomatitis	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.000	0.997	0.003
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.003	0.997	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
I86.4 Gastric varices	0.000	0.997	0.002
S06.7 Intracranial injury with prolonged coma	0.002	0.997	0.000
S06.1 Traumatic cerebral oedema	0.002	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.002	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
Z36 Antenatal screening	0.000	0.997	0.003
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.998	0.000
Q39.4 Oesophageal web	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
I87.1 Compression of vein	0.000	0.998	0.002
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.998	0.002
I87.9 Disorder of vein, unspecified	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.002	0.998	0.000
M48.0 Spinal stenosis	0.002	0.998	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
Z90.0 Acquired absence of part of head and neck	0.000	0.998	0.002
K52.0 Gastro-enteritis and colitis due to radiation	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
Z36.5 Antenatal screening for isoimmunisation	0.000	0.998	0.002
Z93.2 Ileostomy status	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
N39.4 Other specified urinary incontinence	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.998	0.002
Z43 Attention to artificial openings	0.002	0.998	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.998	0.002
Z43.5 Attention to cyctostomy	0.002	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.002	0.998	0.000
N50.0 Atrophy of testis	0.002	0.998	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.002	0.998	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.002	0.998	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.002	0.998	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.002	0.998	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
W80.9 Unspecified place	0.002	0.998	0.000
Z43.8 Attention to other artificial openings	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
C50.1 Central portion of breast	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
M48.8 Other specified spondylopathies	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.002
Z57.7 Occupational exposure to vibration	0.000	0.998	0.002
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.002
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.002
Z57.1 Occupational exposure to radiation	0.000	0.998	0.002
Z57.0 Occupational exposure to noise	0.000	0.998	0.002
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
J35.2 Hypertrophy of adenoids	0.000	0.998	0.002
Z43.9 Attention to unspecified artificial opening	0.002	0.998	0.000
Z43.7 Attention to artificial vagina	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
K52 Other non-infective gastro-enteritis and colitis	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.998	0.001
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
T14.1 Open wound of unspecified body region	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
K62.6 Ulcer of anus and rectum	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.998	0.000
M46.4 Discitis, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.998	0.002
Y83.4 Other reconstructive surgery	0.000	0.998	0.002
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
M48 Other spondylopathies	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.000	0.998	0.001
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.001	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.001	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.001	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.001	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.001	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.001	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.001	0.998	0.000
Q65 Congenital deformities of hip	0.001	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.998	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.001	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.001	0.998	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.001	0.998	0.000
X49.9 Unspecified place	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations