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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75818885
log Bayes Factor = 10.272
Chromosome 2   position 56,351,058  (GRCh37) Explore rs75818885 on Ensembl!
Variant rs75818885 is part of Cluster X0208

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N81 Female genital prolapse
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
N81.6 Rectocele
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
R06 Abnormalities of breathing
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.991 0.009 0.000
R06.0 Dyspnoea
0.990 0.010 0.000
M54 Dorsalgia
0.986 0.014 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.985 0.015 0.000
I73 Other peripheral vascular diseases
0.979 0.021 0.000
R07 Pain in throat and chest
0.972 0.028 0.000
I73.9 Peripheral vascular disease, unspecified
0.971 0.029 0.000
I20-I25 Ischaemic heart diseases
0.970 0.030 0.000
N36 Other disorders of urethra
0.963 0.037 0.000
M51 Other intervertebral disk disorders
0.958 0.042 0.000
R07.4 Chest pain, unspecified
0.956 0.044 0.000
N81.1 Cystocele
0.955 0.045 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.952 0.048 0.000
I25 Chronic ischaemic heart disease
0.951 0.049 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.945 0.055 0.000
N81.4 Uterovaginal prolapse, unspecified
0.939 0.061 0.000
I25.1 Atherosclerotic heart disease
0.936 0.064 0.000
R04 Haemorrhage from respiratory passages
0.934 0.066 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.933 0.067 0.000
N36.8 Other specified disorders of urethra
0.929 0.071 0.000
I05-I09 Chronic rheumatic heart diseases
0.927 0.073 0.000
M54.5 Low back pain
0.927 0.073 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.926 0.074 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
R79 Other abnormal findings of blood chemistry
0.919 0.081 0.000
R04.2 Haemoptysis
0.918 0.082 0.000
M54.4 Lumbago with sciatica
0.918 0.082 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.916 0.084 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.913 0.087 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
N92 Excessive, frequent and irregular menstruation
0.905 0.095 0.000
M13 Other arthritis
0.904 0.096 0.000
Chapter X Diseases of the respiratory system
0.904 0.096 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.903 0.097 0.000
M51.2 Other specified intervertebral disk displacement
0.898 0.102 0.000
M54.56 Low back pain (Lumbar region)
0.896 0.104 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.895 0.105 0.000
M86-M90 Other osteopathies
0.893 0.107 0.000
I20 Angina pectoris
0.887 0.113 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.883 0.117 0.000
E65-E68 Obesity and other hyperalimentation
0.883 0.117 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.883 0.117 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.882 0.118 0.000
E00-E07 Disorders of thyroid gland
0.880 0.120 0.000
N81.2 Incomplete uterovaginal prolapse
0.877 0.123 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.877 0.123 0.000
I20.9 Angina pectoris, unspecified
0.877 0.123 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
M70-M79 Other soft tissue disorders
0.873 0.127 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.869 0.131 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.865 0.135 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.864 0.136 0.000
R02 Gangrene, not elsewhere classified
0.859 0.141 0.000
E04 Other non-toxic goitre
0.855 0.145 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.852 0.148 0.000
E66 Obesity
0.852 0.148 0.000
N81.8 Other female genital prolapse
0.852 0.148 0.000
N80 Endometriosis
0.852 0.148 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.851 0.149 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.850 0.150 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.849 0.151 0.000
I80 Phlebitis and thrombophlebitis
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.844 0.156 0.000
N99-N99 Other disorders of the genitourinary system
0.842 0.158 0.000
M54.9 Dorsalgia, unspecified
0.839 0.161 0.000
M13.9 Arthritis, unspecified
0.836 0.164 0.000
J40-J47 Chronic lower respiratory diseases
0.834 0.166 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.834 0.166 0.000
N80.0 Endometriosis of uterus
0.832 0.168 0.000
R47-R49 Symptoms and signs involving speech and voice
0.827 0.173 0.000
M40-M43 Deforming dorsopathies
0.827 0.173 0.000
M06.0 Seronegative rheumatoid arthritis
0.826 0.174 0.000
N32 Other disorders of bladder
0.824 0.176 0.000
M54.3 Sciatica
0.823 0.177 0.000
S90-S99 Injuries to the ankle and foot
0.821 0.179 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.819 0.181 0.000
I07 Rheumatic tricuspid valve diseases
0.816 0.184 0.000
R06.8 Other and unspecified abnormalities of breathing
0.815 0.185 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.814 0.186 0.000
I74 Arterial embolism and thrombosis
0.812 0.188 0.000
E04.9 Non-toxic goitre, unspecified
0.812 0.188 0.000
M45-M49 Spondylopathies
0.804 0.196 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.800 0.200 0.000
E66.9 Obesity, unspecified
0.800 0.200 0.000
J60-J70 Lung diseases due to external agents
0.799 0.201 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.799 0.201 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.798 0.202 0.000
E04.2 Non-toxic multinodular goitre
0.797 0.202 0.000
N92.5 Other specified irregular menstruation
0.797 0.203 0.000
R87 Abnormal findings in specimens from female genital organs
0.797 0.203 0.000
S80-S89 Injuries to the knee and lower leg
0.792 0.208 0.000
M54.6 Pain in thoracic spine
0.792 0.208 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.789 0.211 0.000
I22 Subsequent myocardial infarction
0.788 0.212 0.000
N36.2 Urethral caruncle
0.788 0.212 0.000
I08 Multiple valve diseases
0.787 0.213 0.000
J44 Other chronic obstructive pulmonary disease
0.787 0.213 0.000
M51.9 Intervertebral disk disorder, unspecified
0.786 0.214 0.000
N93 Other abnormal uterine and vaginal bleeding
0.786 0.214 0.000
I70 Atherosclerosis
0.786 0.214 0.000
N30 Cystitis
0.783 0.217 0.000
M75 Shoulder lesions
0.782 0.218 0.000
M91-M94 Chondropathies
0.780 0.220 0.000
N34 Urethritis and urethral syndrome
0.780 0.220 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.778 0.221 0.000
G90-G99 Other disorders of the nervous system
0.777 0.223 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.777 0.223 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.776 0.224 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.775 0.225 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.775 0.225 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.775 0.225 0.000
N32.8 Other specified disorders of bladder
0.775 0.225 0.000
N60-N64 Disorders of breast
0.775 0.225 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.769 0.231 0.000
R74 Abnormal serum enzyme levels
0.767 0.233 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.766 0.234 0.000
G70-G73 Diseases of myoneural junction and muscle
0.765 0.235 0.000
I72 Other aneurysm
0.764 0.236 0.000
N84 Polyp of female genital tract
0.764 0.236 0.000
M65 Synovitis and tenosynovitis
0.763 0.237 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.761 0.239 0.000
I77 Other disorders of arteries and arterioles
0.761 0.239 0.000
R06.4 Hyperventilation
0.760 0.240 0.000
I83 Varicose veins of lower extremities
0.757 0.243 0.000
T92 Sequelae of injuries of upper limb
0.755 0.245 0.000
R07.0 Pain in throat
0.755 0.245 0.000
E10-E14 Diabetes mellitus
0.754 0.246 0.000
M89 Other disorders of bone
0.753 0.247 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.753 0.247 0.000
R79.0 Abnormal level of blood mineral
0.751 0.249 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.751 0.249 0.000
E66.8 Other obesity
0.751 0.249 0.000
J90-J94 Other diseases of pleura
0.750 0.250 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.749 0.251 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.747 0.253 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.746 0.253 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.746 0.254 0.000
N88 Other noninflammatory disorders of cervix uteri
0.745 0.255 0.000
M46 Other inflammatory spondylopathies
0.743 0.257 0.000
N97 Female infertility
0.742 0.258 0.000
M05 Seropositive rheumatoid arthritis
0.740 0.260 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.736 0.263 0.000
S50-S59 Injuries to the elbow and forearm
0.736 0.264 0.000
I07.1 Tricuspid insufficiency
0.735 0.265 0.000
T93 Sequelae of injuries of lower limb
0.734 0.266 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.733 0.267 0.000
G40-G47 Episodic and paroxysmal disorders
0.733 0.267 0.000
M51.8 Other specified intervertebral disk disorders
0.733 0.267 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.732 0.268 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.730 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.729 0.270 0.000
Q80-Q89 Other congenital malformations
0.729 0.271 0.000
Y40 Systemic antibiotics
0.727 0.273 0.000
T43.2 Other and unspecified antidepressants
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
F41 Other anxiety disorders
0.723 0.277 0.000
M10 Gout
0.722 0.278 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.722 0.278 0.000
R87.6 Abnormal cytological findings
0.721 0.279 0.000
J95-J99 Other diseases of the respiratory system
0.719 0.281 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.719 0.281 0.000
E11 Non-insulin-dependent diabetes mellitus
0.719 0.281 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.718 0.282 0.000
M75.3 Calcific tendinitis of shoulder
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R76 Other abnormal immunological findings in serum
0.717 0.283 0.000
N81.0 Female urethrocele
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.716 0.283 0.000
N91 Absent, scanty and rare menstruation
0.716 0.283 0.000
N82 Fistulae involving female genital tract
0.716 0.283 0.000
N96 Habitual aborter
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M07 Psoriatic and enteropathic arthropathies
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.3 Rheumatoid nodule
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.285 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.715 0.285 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.715 0.285 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.715 0.285 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.715 0.285 0.000
J46 Status asthmaticus
0.715 0.285 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
N10-N16 Renal tubulo-interstitial diseases
0.714 0.286 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.714 0.286 0.000
N36.3 Prolapsed urethral mucosa
0.713 0.287 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.712 0.288 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.712 0.288 0.000
R06.7 Sneezing
0.712 0.288 0.000
R06.3 Periodic breathing
0.712 0.288 0.000
R06.2 Wheezing
0.712 0.288 0.000
J40 Bronchitis, not specified as acute or chronic
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.712 0.288 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.711 0.289 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.711 0.289 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.711 0.289 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.711 0.289 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.711 0.289 0.000
R06.6 Hiccough
0.710 0.290 0.000
I08.0 Disorders of both mitral and aortic valves
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
S92 Fracture of foot, except ankle
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.708 0.292 0.000
M54.8 Other dorsalgia
0.707 0.293 0.000
M54.0 Panniculitis affecting regions of neck and back
0.707 0.293 0.000
M75.4 Impingement syndrome of shoulder
0.706 0.294 0.000
J69 Pneumonitis due to solids and liquids
0.706 0.294 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.704 0.296 0.000
N60 Benign mammary dysplasia
0.704 0.296 0.000
N87 Dysplasia of cervix uteri
0.704 0.296 0.000
M50 Cervical disk disorders
0.702 0.298 0.000
I73.8 Other specified peripheral vascular diseases
0.702 0.298 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.702 0.298 0.000
R07.1 Chest pain on breathing
0.702 0.298 0.000
J93 Pneumothorax
0.702 0.298 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.702 0.298 0.000
I05 Rheumatic mitral valve diseases
0.702 0.298 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.701 0.299 0.000
R06.1 Stridor
0.698 0.301 0.000
M66 Spontaneous rupture of synovium and tendon
0.698 0.302 0.000
T90 Sequelae of injuries of head
0.698 0.302 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.696 0.304 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.696 0.304 0.000
I23 Certain current complications following acute myocardial infarction
0.695 0.305 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.695 0.305 0.000
W00-W19 Falls
0.694 0.306 0.000
M41 Scoliosis
0.693 0.307 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.693 0.307 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.693 0.307 0.000
M87 Osteonecrosis
0.692 0.307 0.000
N36.0 Urethral fistula
0.692 0.308 0.000
M88 Paget's disease of bone [osteitis deformans]
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.691 0.308 0.000
N36.9 Urethral disorder, unspecified
0.691 0.309 0.000
N36.1 Urethral diverticulum
0.691 0.309 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.690 0.309 0.000
N80.9 Endometriosis, unspecified
0.689 0.311 0.000
N92.4 Excessive bleeding in the premenopausal period
0.688 0.312 0.000
R07.3 Other chest pain
0.688 0.312 0.000
N32.0 Bladder-neck obstruction
0.688 0.312 0.000
J43 Emphysema
0.687 0.313 0.000
M51.3 Other specified intervertebral disk degeneration
0.687 0.313 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.687 0.313 0.000
M51.4 Schmorl's nodes
0.687 0.313 0.000
F41.2 Mixed anxiety and depressive disorder
0.686 0.314 0.000
N25-N29 Other disorders of kidney and ureter
0.685 0.315 0.000
I78 Diseases of capillaries
0.684 0.316 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.683 0.316 0.000
M13.94 Arthritis, unspecified (Hand)
0.683 0.317 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.682 0.317 0.000
R77 Other abnormalities of plasma proteins
0.682 0.317 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.682 0.317 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.682 0.317 0.000
R71 Abnormality of red blood cells
0.682 0.317 0.000
I25.6 Silent myocardial ischaemia
0.682 0.318 0.000
I25.4 Coronary artery aneurysm
0.682 0.318 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.682 0.318 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.681 0.319 0.000
G95 Other diseases of spinal cord
0.681 0.319 0.000
N35 Urethral stricture
0.680 0.320 0.000
G81 Hemiplegia
0.680 0.320 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.679 0.320 0.000
T42.4 Benzodiazepines
0.679 0.321 0.000
N92.6 Irregular menstruation, unspecified
0.678 0.322 0.000
F41.9 Anxiety disorder, unspecified
0.678 0.322 0.000
G35 Multiple sclerosis
0.678 0.322 0.000
T33-T35 Frostbite
0.677 0.322 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.677 0.322 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.677 0.322 0.000
T00-T07 Injuries involving multiple body regions
0.677 0.322 0.000
I73.0 Raynaud's syndrome
0.676 0.324 0.000
W50-W64 Exposure to animate mechanical forces
0.676 0.324 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.676 0.324 0.000
R47 Speech disturbances, not elsewhere classified
0.676 0.324 0.000
I25.3 Aneurysm of heart
0.674 0.325 0.000
Y52 Agents primarily affecting the cardiovascular system
0.674 0.326 0.000
E40-E46 Malnutrition
0.673 0.327 0.000
N73 Other female pelvic inflammatory diseases
0.672 0.328 0.000
M86 Osteomyelitis
0.671 0.329 0.000
S70-S79 Injuries to the hip and thigh
0.670 0.330 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.669 0.330 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.669 0.330 0.000
R04.1 Haemorrhage from throat
0.669 0.330 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.666 0.333 0.000
F99-F99 Unspecified mental disorder
0.666 0.333 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
M72 Fibroblastic disorders
0.666 0.334 0.000
I74.5 Embolism and thrombosis of iliac artery
0.666 0.334 0.000
J92 Pleural plaque
0.666 0.334 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.665 0.335 0.000
I09 Other rheumatic heart diseases
0.665 0.335 0.000
I06 Rheumatic aortic valve diseases
0.665 0.335 0.000
M54.55 Low back pain (Thoracolumbar region)
0.665 0.335 0.000
M54.54 Low back pain-Thoracic
0.665 0.335 0.000
M54.53 Low back pain-Cervicothoracic
0.665 0.335 0.000
M54.52 Low back pain-Cervical
0.665 0.335 0.000
M54.51 Low back pain-Occipit-atl-axl
0.665 0.335 0.000
M54.50 Low back pain (Multiple sites in spine)
0.665 0.335 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.662 0.338 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.659 0.340 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.659 0.341 0.000
Y48 Anaesthetics and therapeutic gases
0.658 0.342 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.658 0.342 0.000
M54.44 Lumbago with sciatica-Thoracic
0.658 0.342 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.658 0.342 0.000
M54.42 Lumbago with sciatica-Cervical
0.658 0.342 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.658 0.342 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.658 0.342 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.658 0.342 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.657 0.343 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.657 0.343 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.657 0.343 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.657 0.343 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.657 0.343 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.657 0.343 0.000
T36 Poisoning by systemic antibiotics
0.657 0.343 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.657 0.343 0.000
F70-F79 Mental retardation
0.657 0.343 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.656 0.344 0.000
E11.9 Without complications
0.656 0.344 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.656 0.344 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.655 0.345 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.654 0.345 0.000
I25.5 Ischaemic cardiomyopathy
0.654 0.346 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.654 0.346 0.000
I86 Varicose veins of other sites
0.654 0.346 0.000
N84.1 Polyp of cervix uteri
0.654 0.346 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.653 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.652 0.347 0.000
Y10-Y34 Event of undetermined intent
0.652 0.347 0.000
X85-X99 Assault
0.652 0.347 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.652 0.347 0.000
X30-X39 Exposure to forces of nature
0.652 0.347 0.000
X10-X19 Contact with heat and hot substances
0.652 0.347 0.000
X00-X09 Exposure to smoke, fire and flames
0.652 0.347 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.652 0.347 0.000
W75-W84 Other accidental threats to breathing
0.652 0.347 0.000
W65-W74 Accidental drowning and submersion
0.652 0.347 0.000
V98-V99 Other and unspecified transport accidents
0.652 0.347 0.000
V95-V97 Air and space transport accidents
0.652 0.347 0.000
V90-V94 Water transport accidents
0.652 0.347 0.000
V70-V79 Bus occupant injured in transport accident
0.652 0.347 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.652 0.347 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.652 0.347 0.000
V40-V49 Car occupant injured in transport accident
0.652 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.652 0.347 0.000
V01-V09 Pedestrian injured in transport accident
0.652 0.347 0.000
V10-V19 Pedal cyclist injured in transport accident
0.652 0.348 0.000
M40 Kyphosis and lordosis
0.652 0.348 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.651 0.349 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.650 0.350 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.650 0.350 0.000
M54.37 Sciatica (Lumbosacral region)
0.650 0.350 0.000
M13.98 Arthritis, unspecified (Other)
0.650 0.350 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.650 0.350 0.000
N92.2 Excessive menstruation at puberty
0.649 0.351 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.649 0.351 0.000
S10-S19 Injuries to the neck
0.649 0.351 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.649 0.351 0.000
M13.8 Other specified arthritis
0.648 0.352 0.000
M13.1 Monoarthritis, not elsewhere classified
0.648 0.352 0.000
M13.0 Polyarthritis, unspecified
0.648 0.352 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.648 0.352 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.648 0.352 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.647 0.352 0.000
R83 Abnormal findings in cerebrospinal fluid
0.647 0.352 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.645 0.355 0.000
R90.0 Intracranial space-occupying lesion
0.645 0.355 0.000
N30.2 Other chronic cystitis
0.645 0.355 0.000
M75.2 Bicipital tendinitis
0.645 0.355 0.000
F60-F69 Disorders of adult personality and behaviour
0.644 0.356 0.000
M65.8 Other synovitis and tenosynovitis
0.644 0.356 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
V20-V29 Motorcycle rider injured in transport accident
0.644 0.356 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.643 0.356 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.643 0.357 0.000
T91 Sequelae of injuries of neck and trunk
0.643 0.357 0.000
N81.9 Female genital prolapse, unspecified
0.641 0.358 0.000
F80-F89 Disorders of psychological development
0.641 0.359 0.000
M54.59 Low back pain (Site unspecified)
0.641 0.359 0.000
Y40.0 Penicillins
0.641 0.359 0.000
X20-X29 Contact with venomous animals and plants
0.640 0.359 0.000
J69.0 Pneumonitis due to food and vomit
0.640 0.360 0.000
M90 Osteopathies in diseases classified elsewhere
0.640 0.360 0.000
R01 Cardiac murmurs and other cardiac sounds
0.639 0.361 0.000
R49 Voice disturbances
0.638 0.362 0.000
S52 Fracture of forearm
0.637 0.363 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.637 0.363 0.000
M76 Enthesopathies of lower limb, excluding foot
0.636 0.363 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.636 0.363 0.000
R74.8 Abnormal levels of other serum enzymes
0.635 0.365 0.000
J93.1 Other spontaneous pneumothorax
0.635 0.365 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.635 0.365 0.000
N75 Diseases of Bartholin's gland
0.635 0.365 0.000
I74.8 Embolism and thrombosis of other arteries
0.634 0.366 0.000
R09.0 Asphyxia
0.634 0.366 0.000
T98 Sequelae of other and unspecified effects of external causes
0.633 0.367 0.000
T95 Sequelae of burns, corrosions and frostbite
0.633 0.367 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.633 0.367 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.633 0.367 0.000
E67 Other hyperalimentation
0.633 0.367 0.000
E68 Sequelae of hyperalimentation
0.633 0.367 0.000
E65 Localised adiposity
0.633 0.367 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.633 0.367 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.633 0.367 0.000
N94.1 Dyspareunia
0.632 0.367 0.000
T43.9 Psychotropic drug, unspecified
0.632 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
T43.6 Psychostimulants with abuse potential
0.632 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.632 0.368 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.631 0.369 0.000
E00 Congenital iodine-deficiency syndrome
0.631 0.369 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.631 0.369 0.000
S92.0 Fracture of calcaneus
0.630 0.370 0.000
N88.2 Stricture and stenosis of cervix uteri
0.627 0.373 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.627 0.373 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.627 0.373 0.000
S91 Open wound of ankle and foot
0.626 0.374 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.626 0.374 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.626 0.374 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.626 0.374 0.000
Q50-Q56 Congenital malformations of genital organs
0.625 0.375 0.000
Q60-Q64 Congenital malformations of the urinary system
0.625 0.375 0.000
S20-S29 Injuries to the thorax
0.624 0.375 0.000
J92.9 Pleural plaque without asbestos
0.624 0.376 0.000
I88 Nonspecific lymphadenitis
0.623 0.377 0.000
N34.3 Urethral syndrome, unspecified
0.623 0.377 0.000
I27 Other pulmonary heart diseases
0.622 0.378 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.622 0.378 0.000
R94 Abnormal results of function studies
0.621 0.379 0.000
G96 Other disorders of central nervous system
0.620 0.380 0.000
M11 Other crystal arthropathies
0.620 0.380 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.620 0.380 0.000
M71 Other bursopathies
0.619 0.380 0.000
N70 Salpingitis and oophoritis
0.619 0.381 0.000
R86 Abnormal findings in specimens from male genital organs
0.619 0.381 0.000
S82 Fracture of lower leg, including ankle
0.619 0.381 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.619 0.381 0.000
Y44 Agents primarily affecting blood constituents
0.619 0.381 0.000
G70 Myasthenia gravis and other myoneural disorders
0.618 0.382 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.617 0.383 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.615 0.385 0.000
E04.8 Other specified non-toxic goitre
0.613 0.387 0.000
E04.0 Non-toxic diffuse goitre
0.613 0.387 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.612 0.388 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.612 0.388 0.000
S83.2 Tear of meniscus, current
0.612 0.388 0.000
M54.57 Low back pain (Lumbosacral region)
0.612 0.388 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.611 0.389 0.000
I20.1 Angina pectoris with documented spasm
0.611 0.389 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.611 0.389 0.000
E66.1 Drug-induced obesity
0.611 0.389 0.000
E66.0 Obesity due to excess calories
0.611 0.389 0.000
N80.6 Endometriosis in cutaneous scar
0.611 0.389 0.000
N80.5 Endometriosis of intestine
0.611 0.389 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.611 0.389 0.000
G30-G32 Other degenerative diseases of the nervous system
0.611 0.389 0.000
Y59 Other and unspecified vaccines and biological substances
0.610 0.390 0.000
Y58 Bacterial vaccines
0.610 0.390 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.610 0.390 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.610 0.390 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.610 0.390 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.610 0.390 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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