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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75885813
log Bayes Factor = 12.9219
Chromosome 16   position 7,141,263  (GRCh37) Explore rs75885813 on Ensembl!
Variant rs75885813 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
I60-I69 Cerebrovascular diseases
0.982 0.018 0.000
T81 Complications of procedures, not elsewhere classified
0.979 0.021 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.973 0.027 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.968 0.032 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.959 0.041 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.958 0.042 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.951 0.049 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.947 0.053 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.945 0.055 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.938 0.062 0.000
R07 Pain in throat and chest
0.937 0.063 0.000
I20-I25 Ischaemic heart diseases
0.936 0.064 0.000
I10-I15 Hypertensive diseases
0.933 0.067 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.931 0.069 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.931 0.069 0.000
Chapter VII Diseases of the eye and adnexa
0.926 0.074 0.000
I63 Cerebral infarction
0.925 0.075 0.000
N40-N51 Diseases of male genital organs
0.925 0.075 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.923 0.077 0.000
R07.3 Other chest pain
0.922 0.078 0.000
M70-M79 Other soft tissue disorders
0.920 0.080 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.918 0.082 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.916 0.084 0.000
I69 Sequelae of cerebrovascular disease
0.913 0.087 0.000
I49 Other cardiac arrhythmias
0.912 0.088 0.000
S20-S29 Injuries to the thorax
0.909 0.091 0.000
M75 Shoulder lesions
0.907 0.093 0.000
N20-N23 Urolithiasis
0.906 0.094 0.000
Chapter VI Diseases of the nervous system
0.906 0.094 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.902 0.098 0.000
I34 Nonrheumatic mitral valve disorders
0.900 0.100 0.000
Z88.6 Personal history of allergy to analgesic agent
0.899 0.101 0.000
Y83.6 Removal of other organ (partial) (total)
0.898 0.102 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.896 0.104 0.000
I10 Essential (primary) hypertension
0.895 0.105 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.894 0.106 0.000
N10-N16 Renal tubulo-interstitial diseases
0.893 0.107 0.000
I25 Chronic ischaemic heart disease
0.890 0.110 0.000
M75.4 Impingement syndrome of shoulder
0.886 0.114 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.886 0.114 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.882 0.118 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.880 0.120 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.876 0.123 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.872 0.128 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.868 0.132 0.000
I73 Other peripheral vascular diseases
0.867 0.133 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.865 0.135 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.863 0.137 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.862 0.138 0.000
N99-N99 Other disorders of the genitourinary system
0.860 0.140 0.000
F17.2 Dependence syndrome
0.860 0.140 0.000
I63.9 Cerebral infarction, unspecified
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.857 0.142 0.000
S60-S69 Injuries to the wrist and hand
0.856 0.144 0.000
F30-F39 Mood [affective] disorders
0.855 0.145 0.000
E10 Insulin-dependent diabetes mellitus
0.855 0.145 0.000
N60-N64 Disorders of breast
0.845 0.155 0.000
E14 Unspecified diabetes mellitus
0.843 0.157 0.000
E70-E90 Metabolic disorders
0.841 0.159 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.840 0.160 0.000
R00 Abnormalities of heart beat
0.840 0.160 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.837 0.163 0.000
I34.0 Mitral (valve) insufficiency
0.837 0.163 0.000
N20 Calculus of kidney and ureter
0.834 0.166 0.000
I50 Heart failure
0.833 0.167 0.000
I49.9 Cardiac arrhythmia, unspecified
0.832 0.168 0.000
I47 Paroxysmal tachycardia
0.832 0.168 0.000
Z95.1 Presence of aortocoronary bypass graft
0.831 0.169 0.000
S80-S89 Injuries to the knee and lower leg
0.830 0.170 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.828 0.172 0.000
Z88.2 Personal history of allergy to sulphonamides
0.827 0.173 0.000
Y83.8 Other surgical procedures
0.827 0.173 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.824 0.176 0.000
Z87 Personal history of other diseases and conditions
0.824 0.176 0.000
R20 Disturbances of skin sensation
0.821 0.179 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.819 0.181 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.818 0.182 0.000
H02 Other disorders of eyelid
0.818 0.182 0.000
N45 Orchitis and epididymitis
0.817 0.183 0.000
D50-D53 Nutritional anaemias
0.815 0.185 0.000
E20-E35 Disorders of other endocrine glands
0.814 0.186 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.813 0.187 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.811 0.189 0.000
H30-H36 Disorders of choroid and retina
0.810 0.190 0.000
N30-N39 Other diseases of urinary system
0.809 0.191 0.000
N13 Obstructive and reflux uropathy
0.805 0.195 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.803 0.197 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.802 0.198 0.000
Z93 Artificial opening status
0.802 0.198 0.000
G40-G47 Episodic and paroxysmal disorders
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.798 0.202 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.797 0.203 0.000
F32 Depressive episode
0.795 0.205 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.790 0.210 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.788 0.212 0.000
Z99.1 Dependence on respirator
0.788 0.212 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.788 0.212 0.000
I67 Other cerebrovascular diseases
0.785 0.215 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.785 0.215 0.000
F60-F69 Disorders of adult personality and behaviour
0.782 0.218 0.000
R00.0 Tachycardia, unspecified
0.782 0.218 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.782 0.218 0.000
M45-M49 Spondylopathies
0.780 0.220 0.000
E65-E68 Obesity and other hyperalimentation
0.780 0.220 0.000
F17.1 Harmful use
0.777 0.223 0.000
D50 Iron deficiency anaemia
0.776 0.224 0.000
E50-E64 Other nutritional deficiencies
0.776 0.224 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.776 0.224 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.775 0.225 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.771 0.229 0.000
R07.0 Pain in throat
0.770 0.230 0.000
I73.0 Raynaud's syndrome
0.770 0.230 0.000
F03 Unspecified dementia
0.769 0.231 0.000
Z99.3 Dependence on wheelchair
0.769 0.231 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.768 0.232 0.000
I24 Other acute ischaemic heart diseases
0.767 0.233 0.000
I38 Endocarditis, valve unspecified
0.767 0.233 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.767 0.233 0.000
I25.1 Atherosclerotic heart disease
0.765 0.235 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.765 0.235 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.764 0.236 0.000
H02.8 Other specified disorders of eyelid
0.762 0.238 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.761 0.239 0.000
Chapter VIII Diseases of the ear and mastoid process
0.761 0.239 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.760 0.240 0.000
Z97 Presence of other devices
0.757 0.243 0.000
E11 Non-insulin-dependent diabetes mellitus
0.756 0.244 0.000
I45 Other conduction disorders
0.755 0.245 0.000
R20.2 Paraesthesia of skin
0.755 0.245 0.000
Z87.0 Personal history of diseases of the respiratory system
0.755 0.245 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.754 0.246 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.247 0.000
I73.9 Peripheral vascular disease, unspecified
0.752 0.248 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.750 0.250 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.750 0.250 0.000
M80-M85 Disorders of bone density and structure
0.750 0.250 0.000
Y83.4 Other reconstructive surgery
0.749 0.251 0.000
W00-W19 Falls
0.747 0.253 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
N64 Other disorders of breast
0.745 0.255 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
S22.4 Multiple fractures of ribs
0.745 0.255 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.744 0.256 0.000
I25.2 Old myocardial infarction
0.744 0.256 0.000
Z87.8 Personal history of other specified conditions
0.742 0.258 0.000
N20.1 Calculus of ureter
0.740 0.260 0.000
D50.9 Iron deficiency anaemia, unspecified
0.740 0.260 0.000
I77 Other disorders of arteries and arterioles
0.740 0.260 0.000
Z43 Attention to artificial openings
0.740 0.260 0.000
T39.1 4-Aminophenol derivatives
0.739 0.261 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.739 0.261 0.000
F99-F99 Unspecified mental disorder
0.738 0.261 0.000
E78.5 Hyperlipidaemia, unspecified
0.738 0.262 0.000
I69.3 Sequelae of cerebral infarction
0.738 0.262 0.000
N25-N29 Other disorders of kidney and ureter
0.737 0.263 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.737 0.263 0.000
I47.2 Ventricular tachycardia
0.737 0.263 0.000
N85.2 Hypertrophy of uterus
0.736 0.264 0.000
S20 Superficial injury of thorax
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.735 0.265 0.000
G40 Epilepsy
0.735 0.265 0.000
Z99.8 Dependence on other enabling machines and devices
0.734 0.266 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.734 0.266 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.733 0.267 0.000
N50 Other disorders of male genital organs
0.733 0.267 0.000
Z47 Other orthopaedic follow-up care
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.270 0.000
N43 Hydrocele and spermatocele
0.729 0.271 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.728 0.272 0.000
R09.1 Pleurisy
0.727 0.273 0.000
H35 Other retinal disorders
0.726 0.274 0.000
I61 Intracerebral haemorrhage
0.726 0.274 0.000
N42 Other disorders of prostate
0.726 0.274 0.000
F32.9 Depressive episode, unspecified
0.724 0.276 0.000
E10.9 Without complications
0.723 0.277 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.722 0.278 0.000
M75.5 Bursitis of shoulder
0.721 0.279 0.000
H00 Hordeolum and chalazion
0.721 0.279 0.000
H55-H59 Other disorders of eye and adnexa
0.720 0.280 0.000
I74 Arterial embolism and thrombosis
0.720 0.280 0.000
M75.1 Rotator cuff syndrome
0.719 0.281 0.000
I60 Subarachnoid haemorrhage
0.718 0.282 0.000
M75.0 Adhesive capsulitis of shoulder
0.718 0.282 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.718 0.282 0.000
H36 Retinal disorders in diseases classified elsewhere
0.718 0.282 0.000
I50.0 Congestive heart failure
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
H02.1 Ectropion of eyelid
0.716 0.284 0.000
S82 Fracture of lower leg, including ankle
0.716 0.284 0.000
Y83.3 Surgical operation with formation of external stoma
0.716 0.284 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.715 0.285 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.714 0.286 0.000
N93 Other abnormal uterine and vaginal bleeding
0.714 0.286 0.000
S40-S49 Injuries to the shoulder and upper arm
0.714 0.286 0.000
N21 Calculus of lower urinary tract
0.713 0.287 0.000
E14.9 Without complications
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.288 0.000
N92 Excessive, frequent and irregular menstruation
0.711 0.289 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.710 0.290 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.709 0.291 0.000
Chapter XXII Codes for special purposes
0.709 0.291 0.000
I49.5 Sick sinus syndrome
0.709 0.291 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.707 0.293 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
I49.0 Ventricular fibrillation and flutter
0.706 0.294 0.000
I31 Other diseases of pericardium
0.706 0.294 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.706 0.294 0.000
S61 Open wound of wrist and hand
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.704 0.296 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.704 0.296 0.000
I62 Other nontraumatic intracranial haemorrhage
0.704 0.296 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.703 0.297 0.000
I46 Cardiac arrest
0.703 0.297 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.702 0.298 0.000
T81.9 Unspecified complication of procedure
0.702 0.298 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.702 0.298 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.702 0.298 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
E14.3 With ophthalmic complications
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.298 0.000
I33 Acute and subacute endocarditis
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
M71 Other bursopathies
0.701 0.299 0.000
N94.3 Premenstrual tension syndrome
0.700 0.300 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.700 0.300 0.000
M65-M68 Disorders of synovium and tendon
0.699 0.301 0.000
S90-S99 Injuries to the ankle and foot
0.699 0.301 0.000
R07.1 Chest pain on breathing
0.698 0.302 0.000
N41 Inflammatory diseases of prostate
0.698 0.302 0.000
Z89 Acquired absence of limb
0.698 0.302 0.000
Z84 Family history of other conditions
0.698 0.302 0.000
Z81 Family history of mental and behavioural disorders
0.698 0.302 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.697 0.303 0.000
N88 Other noninflammatory disorders of cervix uteri
0.697 0.303 0.000
S22.40 Multiple fractures of ribs (closed)
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.694 0.306 0.000
R07.2 Precordial pain
0.694 0.306 0.000
H43-H45 Disorders of vitreous body and globe
0.694 0.306 0.000
Z93.1 Gastrostomy status
0.693 0.307 0.000
Y83.9 Surgical procedure, unspecified
0.693 0.307 0.000
E10.3 With ophthalmic complications
0.693 0.307 0.000
Z80 Family history of malignant neoplasm
0.692 0.308 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.309 0.000
S32 Fracture of lumbar spine and pelvis
0.691 0.309 0.000
N84 Polyp of female genital tract
0.689 0.311 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.687 0.313 0.000
R07.4 Chest pain, unspecified
0.686 0.314 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.686 0.314 0.000
I50.1 Left ventricular failure
0.685 0.315 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.684 0.316 0.000
I70 Atherosclerosis
0.683 0.317 0.000
I22 Subsequent myocardial infarction
0.682 0.318 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.682 0.318 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.682 0.318 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.682 0.318 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.682 0.318 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.318 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.682 0.318 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.682 0.318 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
T36 Poisoning by systemic antibiotics
0.682 0.318 0.000
N94.1 Dyspareunia
0.682 0.318 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.681 0.319 0.000
E13 Other specified diabetes mellitus
0.681 0.319 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.319 0.000
Y40 Systemic antibiotics
0.680 0.320 0.000
D80-D89 Certain disorders involving the immune mechanism
0.680 0.320 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.677 0.322 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.677 0.323 0.000
R06 Abnormalities of breathing
0.676 0.324 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.675 0.325 0.000
I34.1 Mitral (valve) prolapse
0.675 0.325 0.000
Z46 Fitting and adjustment of other devices
0.675 0.325 0.000
G40.9 Epilepsy, unspecified
0.675 0.325 0.000
M40-M43 Deforming dorsopathies
0.674 0.326 0.000
I49.8 Other specified cardiac arrhythmias
0.673 0.326 0.000
N20.9 Urinary calculus, unspecified
0.673 0.327 0.000
E22 Hyperfunction of pituitary gland
0.673 0.327 0.000
M47 Spondylosis
0.673 0.327 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.672 0.327 0.000
N89 Other noninflammatory disorders of vagina
0.672 0.327 0.000
M91-M94 Chondropathies
0.672 0.327 0.000
M86-M90 Other osteopathies
0.672 0.327 0.000
M60-M63 Disorders of muscles
0.672 0.327 0.000
M00-M03 Infectious arthropathies
0.672 0.327 0.000
I23 Certain current complications following acute myocardial infarction
0.671 0.329 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.670 0.330 0.000
E10.1 With ketoacidosis
0.670 0.330 0.000
Z90.3 Acquired absence of part of stomach
0.670 0.330 0.000
I15 Secondary hypertension
0.669 0.331 0.000
I13 Hypertensive heart and renal disease
0.669 0.331 0.000
I11 Hypertensive heart disease
0.669 0.331 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.668 0.332 0.000
N70 Salpingitis and oophoritis
0.668 0.332 0.000
N00-N08 Glomerular diseases
0.667 0.332 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.667 0.332 0.000
I72 Other aneurysm
0.667 0.332 0.000
Z95.3 Presence of xenogenic heart valve
0.667 0.333 0.000
Z88.5 Personal history of allergy to narcotic agent
0.667 0.333 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.666 0.334 0.000
R01 Cardiac murmurs and other cardiac sounds
0.665 0.335 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.664 0.336 0.000
H10-H13 Disorders of conjunctiva
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.664 0.336 0.000
I25.5 Ischaemic cardiomyopathy
0.663 0.336 0.000
I63.8 Other cerebral infarction
0.663 0.337 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.663 0.337 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.663 0.337 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.663 0.337 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.663 0.337 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.663 0.337 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.663 0.337 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.663 0.337 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.663 0.337 0.000
N46 Male infertility
0.663 0.337 0.000
N44 Torsion of testis
0.663 0.337 0.000
S00-S09 Injuries to the head
0.662 0.338 0.000
Y83.5 Amputation of limb(s)
0.662 0.338 0.000
Y83.0 Surgical operation with transplant of whole organ
0.662 0.338 0.000
I20 Angina pectoris
0.661 0.339 0.000
T39.0 Salicylates
0.660 0.340 0.000
M76 Enthesopathies of lower limb, excluding foot
0.660 0.340 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.660 0.340 0.000
Z91.5 Personal history of self-harm
0.659 0.341 0.000
T88.5 Other complications of anaesthesia
0.659 0.341 0.000
N98 Complications associated with artificial fertilisation
0.658 0.342 0.000
N91 Absent, scanty and rare menstruation
0.658 0.342 0.000
N82 Fistulae involving female genital tract
0.658 0.342 0.000
N96 Habitual aborter
0.658 0.342 0.000
N13.6 Pyonephrosis
0.658 0.342 0.000
T51 Toxic effect of alcohol
0.658 0.342 0.000
N97 Female infertility
0.657 0.343 0.000
N94.6 Dysmenorrhoea, unspecified
0.657 0.343 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.656 0.343 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.656 0.343 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.656 0.343 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.656 0.343 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.656 0.343 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.656 0.343 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.656 0.343 0.000
F11 Mental and behavioural disorders due to use of opioids
0.656 0.343 0.000
R47-R49 Symptoms and signs involving speech and voice
0.656 0.344 0.000
N39 Other disorders of urinary system
0.656 0.344 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.656 0.344 0.000
N87 Dysplasia of cervix uteri
0.655 0.345 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.654 0.345 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.654 0.345 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.654 0.345 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.654 0.345 0.000
I49.4 Other and unspecified premature depolarisation
0.654 0.346 0.000
I49.2 Junctional premature depolarisation
0.654 0.346 0.000
I49.1 Atrial premature depolarisation
0.654 0.346 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.654 0.346 0.000
Z93.6 Other artificial openings of urinary tract status
0.652 0.348 0.000
R23 Other skin changes
0.652 0.348 0.000
H36.0 Diabetic retinopathy
0.652 0.348 0.000
N92.3 Ovulation bleeding
0.652 0.348 0.000
S29 Other and unspecified injuries of thorax
0.651 0.348 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.651 0.348 0.000
S26 Injury of heart
0.651 0.348 0.000
S25 Injury of blood vessels of thorax
0.651 0.348 0.000
S24 Injury of nerves and spinal cord at thorax level
0.651 0.348 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.651 0.348 0.000
S21 Open wound of thorax
0.651 0.348 0.000
E27 Other disorders of adrenal gland
0.651 0.348 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.651 0.349 0.000
F01 Vascular dementia
0.651 0.349 0.000
M75.8 Other shoulder lesions
0.651 0.349 0.000
M75.9 Shoulder lesion, unspecified
0.651 0.349 0.000
M75.2 Bicipital tendinitis
0.651 0.349 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.650 0.350 0.000
G70-G73 Diseases of myoneural junction and muscle
0.649 0.350 0.000
G30-G32 Other degenerative diseases of the nervous system
0.649 0.350 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.649 0.350 0.000
T40.2 Other opioids
0.649 0.351 0.000
Z83 Family history of other specific disorders
0.648 0.352 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.647 0.353 0.000
Z88.0 Personal history of allergy to penicillin
0.647 0.353 0.000
M77 Other enthesopathies
0.647 0.353 0.000
Y86 Sequelae of other accidents
0.647 0.353 0.000
I49.3 Ventricular premature depolarisation
0.647 0.353 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.647 0.353 0.000
Z99.4 Dependence on artificial heart
0.647 0.353 0.000
Z99.0 Dependence on aspirator
0.647 0.353 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.646 0.353 0.000
N20.0 Calculus of kidney
0.646 0.354 0.000
S27 Injury of other and unspecified intrathoracic organs
0.646 0.354 0.000
N60 Benign mammary dysplasia
0.646 0.354 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.645 0.354 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.645 0.354 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.645 0.354 0.000
N48 Other disorders of penis
0.645 0.355 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.644 0.356 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.644 0.356 0.000
N62 Hypertrophy of breast
0.643 0.357 0.000
M72 Fibroblastic disorders
0.643 0.357 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.643 0.357 0.000
N86 Erosion and ectropion of cervix uteri
0.643 0.357 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.642 0.358 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.642 0.358 0.000
N83.2 Other and unspecified ovarian cysts
0.642 0.358 0.000
E83 Disorders of mineral metabolism
0.642 0.358 0.000
S68 Traumatic amputation of wrist and hand
0.641 0.359 0.000
F17.9 Unspecified mental and behavioural disorder
0.641 0.359 0.000
F17.8 Other mental and behavioural disorders
0.641 0.359 0.000
F17.7 Residual and late-onset psychotic disorder
0.641 0.359 0.000
F17.6 Amnesic syndrome
0.641 0.359 0.000
F17.5 Psychotic disorder
0.641 0.359 0.000
F17.4 Withdrawal state with delirium
0.641 0.359 0.000
F17.3 Withdrawal state
0.641 0.359 0.000
F17.0 Acute intoxication
0.641 0.359 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.640 0.360 0.000
N15 Other renal tubulo-interstitial diseases
0.640 0.360 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.640 0.360 0.000
N11 Chronic tubulo-interstitial nephritis
0.640 0.360 0.000
N10 Acute tubulo-interstitial nephritis
0.640 0.360 0.000
I51 Complications and ill-defined descriptions of heart disease
0.640 0.360 0.000
H53-H54 Visual disturbances and blindness
0.640 0.360 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.640 0.360 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.639 0.361 0.000
Z94 Transplanted organ and tissue status
0.639 0.361 0.000
E61 Deficiency of other nutrient elements
0.639 0.361 0.000
I25.6 Silent myocardial ischaemia
0.638 0.362 0.000
I25.4 Coronary artery aneurysm
0.638 0.362 0.000
I25.3 Aneurysm of heart
0.638 0.362 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.638 0.362 0.000
M84 Disorders of continuity of bone
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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