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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75886551
log Bayes Factor = 12.6201
Chromosome 6   position 51,028,172  (GRCh37) Explore rs75886551 on Ensembl!
Variant rs75886551 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.998 0.002 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.987 0.013 0.000
Chapter II Neoplasms
0.980 0.020 0.000
I24 Other acute ischaemic heart diseases
0.978 0.022 0.000
E78.0 Pure hypercholesterolaemia
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
E87.7 Fluid overload
0.962 0.038 0.000
E87.6 Hypokalaemia
0.961 0.039 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.961 0.039 0.000
G40-G47 Episodic and paroxysmal disorders
0.961 0.039 0.000
R47-R49 Symptoms and signs involving speech and voice
0.960 0.040 0.000
E86 Volume depletion
0.958 0.042 0.000
E10-E14 Diabetes mellitus
0.957 0.043 0.000
Chapter VIII Diseases of the ear and mastoid process
0.956 0.044 0.000
G40 Epilepsy
0.946 0.054 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.946 0.054 0.000
E20-E35 Disorders of other endocrine glands
0.945 0.055 0.000
I21 Acute myocardial infarction
0.944 0.056 0.000
R47 Speech disturbances, not elsewhere classified
0.944 0.056 0.000
E78.5 Hyperlipidaemia, unspecified
0.936 0.064 0.000
I22 Subsequent myocardial infarction
0.930 0.070 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.929 0.071 0.000
E11 Non-insulin-dependent diabetes mellitus
0.928 0.072 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.926 0.074 0.000
G90-G99 Other disorders of the nervous system
0.925 0.075 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.919 0.081 0.000
M40-M43 Deforming dorsopathies
0.917 0.083 0.000
I24.8 Other forms of acute ischaemic heart disease
0.917 0.083 0.000
E11.9 Without complications
0.912 0.088 0.000
H90-H95 Other disorders of ear
0.911 0.089 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.905 0.095 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.902 0.098 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.900 0.100 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.897 0.103 0.000
R47.8 Other and unspecified speech disturbances
0.896 0.104 0.000
E87.5 Hyperkalaemia
0.895 0.105 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.890 0.110 0.000
I80 Phlebitis and thrombophlebitis
0.888 0.112 0.000
C64-C68 Malignant neoplasms of urinary tract
0.883 0.117 0.000
I30-I52 Other forms of heart disease
0.880 0.120 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.880 0.120 0.000
C50-C50 Malignant neoplasm of breast
0.876 0.124 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.875 0.125 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.872 0.128 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.867 0.133 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.861 0.139 0.000
D46 Myelodysplastic syndromes
0.858 0.142 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.857 0.143 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.856 0.144 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.853 0.147 0.000
R47.0 Dysphasia and aphasia
0.851 0.149 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.851 0.149 0.000
M41 Scoliosis
0.849 0.151 0.000
R20 Disturbances of skin sensation
0.847 0.153 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
H90 Conductive and sensorineural hearing loss
0.840 0.160 0.000
M43 Other deforming dorsopathies
0.839 0.161 0.000
M65-M68 Disorders of synovium and tendon
0.838 0.162 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.837 0.163 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.836 0.164 0.000
E14 Unspecified diabetes mellitus
0.832 0.168 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.831 0.169 0.000
M80-M85 Disorders of bone density and structure
0.830 0.170 0.000
G93 Other disorders of brain
0.828 0.172 0.000
R30-R39 Symptoms and signs involving the urinary system
0.826 0.174 0.000
S50-S59 Injuries to the elbow and forearm
0.824 0.176 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.824 0.176 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.823 0.177 0.000
R25 Abnormal involuntary movements
0.822 0.178 0.000
E28 Ovarian dysfunction
0.822 0.178 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.822 0.178 0.000
E00-E07 Disorders of thyroid gland
0.822 0.178 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.819 0.181 0.000
O80-O84 Delivery
0.812 0.188 0.000
G40.9 Epilepsy, unspecified
0.812 0.188 0.000
V10-V19 Pedal cyclist injured in transport accident
0.811 0.189 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.808 0.192 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.808 0.192 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.807 0.193 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.806 0.194 0.000
C50 Malignant neoplasm of breast
0.801 0.199 0.000
I42 Cardiomyopathy
0.801 0.199 0.000
M41.9 Scoliosis, unspecified
0.800 0.200 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.799 0.201 0.000
Chapter V Mental and behavioural disorders
0.799 0.201 0.000
I25 Chronic ischaemic heart disease
0.798 0.202 0.000
Q60-Q64 Congenital malformations of the urinary system
0.796 0.204 0.000
C15-C26 Malignant neoplasms of digestive organs
0.795 0.205 0.000
M70-M79 Other soft tissue disorders
0.784 0.216 0.000
M43.1 Spondylolisthesis
0.784 0.216 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.784 0.216 0.000
C67 Malignant neoplasm of bladder
0.784 0.216 0.000
I44 Atrioventricular and left bundle-branch block
0.782 0.218 0.000
E78.8 Other disorders of lipoprotein metabolism
0.777 0.223 0.000
I95 Hypotension
0.777 0.223 0.000
E11.1 With ketoacidosis
0.775 0.225 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.775 0.225 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.774 0.226 0.000
E87.3 Alkalosis
0.771 0.229 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.771 0.229 0.000
Chapter X Diseases of the respiratory system
0.771 0.229 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.770 0.230 0.000
E88 Other metabolic disorders
0.770 0.230 0.000
G41 Status epilepticus
0.769 0.231 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.769 0.231 0.000
I21.9 Acute myocardial infarction, unspecified
0.768 0.232 0.000
R32 Unspecified urinary incontinence
0.767 0.233 0.000
I73 Other peripheral vascular diseases
0.766 0.234 0.000
E85 Amyloidosis
0.764 0.235 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.762 0.238 0.000
E78.2 Mixed hyperlipidaemia
0.762 0.238 0.000
Y44 Agents primarily affecting blood constituents
0.760 0.240 0.000
C50.4 Upper-outer quadrant of breast
0.759 0.241 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.756 0.244 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.756 0.244 0.000
E78.4 Other hyperlipidaemia
0.755 0.245 0.000
E20 Hypoparathyroidism
0.754 0.246 0.000
I71 Aortic aneurysm and dissection
0.754 0.246 0.000
E21.3 Hyperparathyroidism, unspecified
0.754 0.246 0.000
R39 Other symptoms and signs involving the urinary system
0.753 0.247 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.752 0.248 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.751 0.249 0.000
D10-D36 Benign neoplasms
0.751 0.249 0.000
S00-S09 Injuries to the head
0.750 0.250 0.000
R47.1 Dysarthria and anarthria
0.750 0.250 0.000
I51 Complications and ill-defined descriptions of heart disease
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.748 0.252 0.000
Y43 Primarily systemic agents
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.746 0.254 0.000
I22.8 Subsequent myocardial infarction of other sites
0.746 0.254 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.745 0.254 0.000
C18 Malignant neoplasm of colon
0.745 0.255 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.743 0.257 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.743 0.257 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.742 0.258 0.000
M45-M49 Spondylopathies
0.740 0.260 0.000
M00-M03 Infectious arthropathies
0.740 0.260 0.000
S20-S29 Injuries to the thorax
0.739 0.261 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.739 0.261 0.000
H90.5 Sensorineural hearing loss, unspecified
0.738 0.262 0.000
E26 Hyperaldosteronism
0.738 0.262 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.736 0.264 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.736 0.264 0.000
H92 Otalgia and effusion of ear
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
E28.2 Polycystic ovarian syndrome
0.734 0.266 0.000
I50 Heart failure
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.733 0.266 0.000
E11.0 With coma
0.732 0.267 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.732 0.268 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.732 0.268 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.732 0.268 0.000
H60-H62 Diseases of external ear
0.732 0.268 0.000
O85-O92 Complications predominantly related to the puerperium
0.731 0.268 0.000
C50.2 Upper-inner quadrant of breast
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.731 0.269 0.000
E11.6 With other specified complications
0.731 0.269 0.000
D80-D89 Certain disorders involving the immune mechanism
0.730 0.270 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.729 0.271 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.729 0.271 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.727 0.273 0.000
E87.0 Hyperosmolality and hypernatraemia
0.727 0.273 0.000
M67 Other disorders of synovium and tendon
0.726 0.274 0.000
D00-D09 In situ neoplasms
0.726 0.274 0.000
I42.9 Cardiomyopathy, unspecified
0.726 0.274 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.725 0.275 0.000
I81 Portal vein thrombosis
0.724 0.276 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.724 0.276 0.000
I05 Rheumatic mitral valve diseases
0.724 0.276 0.000
G96 Other disorders of central nervous system
0.723 0.277 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.723 0.277 0.000
C66 Malignant neoplasm of ureter
0.723 0.277 0.000
D38.1 Trachea, bronchus and lung
0.722 0.278 0.000
S80-S89 Injuries to the knee and lower leg
0.722 0.278 0.000
I44.7 Left bundle-branch block, unspecified
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.722 0.278 0.000
I26 Pulmonary embolism
0.722 0.278 0.000
E24 Cushing's syndrome
0.721 0.279 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.719 0.281 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.718 0.282 0.000
G40.8 Other epilepsy
0.718 0.282 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C67.9 Bladder, unspecified
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
E87.4 Mixed disorder of acid-base balance
0.715 0.285 0.000
E78.6 Lipoprotein deficiency
0.715 0.285 0.000
E78.3 Hyperchylomicronaemia
0.715 0.285 0.000
E78.1 Pure hyperglyceridaemia
0.715 0.285 0.000
G20-G26 Extrapyramidal and movement disorders
0.715 0.285 0.000
I34 Nonrheumatic mitral valve disorders
0.714 0.285 0.000
C71 Malignant neoplasm of brain
0.714 0.286 0.000
M84 Disorders of continuity of bone
0.714 0.286 0.000
Y42.7 Androgens and anabolic congeners
0.713 0.287 0.000
E14.9 Without complications
0.713 0.287 0.000
G93.0 Cerebral cysts
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.289 0.000
I20 Angina pectoris
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.707 0.293 0.000
R76 Other abnormal immunological findings in serum
0.707 0.293 0.000
I21.4 Acute subendocardial myocardial infarction
0.707 0.293 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.707 0.293 0.000
H65-H75 Diseases of middle ear and mastoid
0.706 0.294 0.000
H80-H83 Diseases of inner ear
0.706 0.294 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.705 0.295 0.000
H93 Other disorders of ear, not elsewhere classified
0.704 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
I24.1 Dressler's syndrome
0.701 0.299 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.701 0.299 0.000
D22 Melanocytic naevi
0.700 0.300 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.699 0.301 0.000
R23 Other skin changes
0.698 0.302 0.000
W00-W19 Falls
0.698 0.302 0.000
I46 Cardiac arrest
0.696 0.304 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.696 0.304 0.000
D45 Polycythaemia vera
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.695 0.305 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.693 0.307 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.693 0.307 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
Y00-Y09 Assault
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X20-X29 Contact with venomous animals and plants
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W75-W84 Other accidental threats to breathing
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V80-V89 Other land transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.309 0.000
X60-X84 Intentional self-harm
0.691 0.309 0.000
I99 Other and unspecified disorders of circulatory system
0.691 0.309 0.000
I95.2 Hypotension due to drugs
0.690 0.310 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.690 0.310 0.000
M85 Other disorders of bone density and structure
0.690 0.310 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.690 0.310 0.000
R25.3 Fasciculation
0.690 0.310 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.689 0.311 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.689 0.311 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.689 0.311 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.689 0.311 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.689 0.311 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.688 0.311 0.000
I07 Rheumatic tricuspid valve diseases
0.687 0.313 0.000
C18.7 Sigmoid colon
0.687 0.313 0.000
S51 Open wound of forearm
0.686 0.314 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.686 0.314 0.000
E12 Malnutrition-related diabetes mellitus
0.686 0.314 0.000
C10 Malignant neoplasm of oropharynx
0.686 0.314 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.686 0.314 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.686 0.314 0.000
G47 Sleep disorders
0.685 0.315 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.685 0.315 0.000
E11.4 With neurological complications
0.684 0.316 0.000
E21.0 Primary hyperparathyroidism
0.684 0.316 0.000
S00 Superficial injury of head
0.684 0.316 0.000
Q61 Cystic kidney disease
0.684 0.316 0.000
R25.1 Tremor, unspecified
0.683 0.317 0.000
C18.9 Colon, unspecified
0.683 0.317 0.000
I60-I69 Cerebrovascular diseases
0.681 0.319 0.000
I20.0 Unstable angina
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.679 0.320 0.000
G83 Other paralytic syndromes
0.679 0.321 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.678 0.322 0.000
G40.5 Special epileptic syndromes
0.678 0.322 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.678 0.322 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.678 0.322 0.000
S70-S79 Injuries to the hip and thigh
0.678 0.322 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.678 0.322 0.000
E34 Other endocrine disorders
0.678 0.322 0.000
E32 Diseases of thymus
0.678 0.322 0.000
E31 Polyglandular dysfunction
0.678 0.322 0.000
E30 Disorders of puberty, not elsewhere classified
0.678 0.322 0.000
E25 Adrenogenital disorders
0.678 0.322 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.677 0.323 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.677 0.323 0.000
I51.7 Cardiomegaly
0.677 0.323 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.677 0.323 0.000
O80 Single spontaneous delivery
0.676 0.324 0.000
Y45.1 Salicylates
0.676 0.324 0.000
D23 Other benign neoplasms of skin
0.676 0.324 0.000
G81 Hemiplegia
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
G95 Other diseases of spinal cord
0.675 0.325 0.000
M86-M90 Other osteopathies
0.674 0.326 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.674 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.674 0.326 0.000
E65-E68 Obesity and other hyperalimentation
0.674 0.326 0.000
M65 Synovitis and tenosynovitis
0.673 0.327 0.000
D12.6 Colon, unspecified
0.673 0.327 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.672 0.328 0.000
I72 Other aneurysm
0.671 0.329 0.000
E05.9 Thyrotoxicosis, unspecified
0.670 0.330 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.670 0.330 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.669 0.331 0.000
I50.1 Left ventricular failure
0.669 0.331 0.000
D12.3 Transverse colon
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
I82 Other venous embolism and thrombosis
0.667 0.332 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.667 0.333 0.000
O82 Single delivery by Caesarean section
0.667 0.333 0.000
T33-T35 Frostbite
0.666 0.334 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.334 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.666 0.334 0.000
T00-T07 Injuries involving multiple body regions
0.666 0.334 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
S50 Superficial injury of forearm
0.666 0.334 0.000
R94 Abnormal results of function studies
0.666 0.334 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.666 0.334 0.000
E11.8 With unspecified complications
0.665 0.335 0.000
E11.7 With multiple complications
0.665 0.335 0.000
G93.9 Disorder of brain, unspecified
0.664 0.335 0.000
Y59 Other and unspecified vaccines and biological substances
0.664 0.336 0.000
Y58 Bacterial vaccines
0.664 0.336 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.664 0.336 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.664 0.336 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.664 0.336 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.664 0.336 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.664 0.336 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
Y48 Anaesthetics and therapeutic gases
0.664 0.336 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.664 0.336 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.664 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.663 0.336 0.000
G90 Disorders of autonomic nervous system
0.663 0.336 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.663 0.336 0.000
G92 Toxic encephalopathy
0.663 0.336 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.338 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.662 0.338 0.000
Q50-Q56 Congenital malformations of genital organs
0.661 0.338 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.661 0.339 0.000
D48.7 Other specified sites
0.661 0.339 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.660 0.340 0.000
J60-J70 Lung diseases due to external agents
0.659 0.341 0.000
C50.8 Overlapping lesion of breast
0.659 0.341 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.659 0.341 0.000
Q35-Q37 Cleft lip and cleft palate
0.659 0.341 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.659 0.341 0.000
H91 Other hearing loss
0.659 0.341 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.658 0.342 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.658 0.342 0.000
M42 Spinal osteochondrosis
0.658 0.342 0.000
M40 Kyphosis and lordosis
0.658 0.342 0.000
G93.3 Postviral fatigue syndrome
0.657 0.343 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.657 0.343 0.000
R20.2 Paraesthesia of skin
0.656 0.344 0.000
M91-M94 Chondropathies
0.655 0.345 0.000
D68 Other coagulation defects
0.655 0.345 0.000
E14.3 With ophthalmic complications
0.653 0.347 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.653 0.347 0.000
R49 Voice disturbances
0.653 0.347 0.000
D48.5 Skin
0.652 0.348 0.000
R40 Somnolence, stupor and coma
0.652 0.348 0.000
D22.4 Melanocytic naevi of scalp and neck
0.652 0.348 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.651 0.349 0.000
E23 Hypofunction and other disorders of pituitary gland
0.651 0.349 0.000
I85 Oesophageal varices
0.651 0.349 0.000
G93.2 Benign intracranial hypertension
0.649 0.351 0.000
I86 Varicose veins of other sites
0.649 0.351 0.000
R26 Abnormalities of gait and mobility
0.649 0.351 0.000
C01 Malignant neoplasm of base of tongue
0.649 0.351 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.649 0.351 0.000
E29 Testicular dysfunction
0.647 0.353 0.000
I69 Sequelae of cerebrovascular disease
0.647 0.353 0.000
G44 Other headache syndromes
0.647 0.353 0.000
R42 Dizziness and giddiness
0.646 0.354 0.000
D48.0 Bone and articular cartilage
0.645 0.355 0.000
I30 Acute pericarditis
0.644 0.356 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.644 0.356 0.000
I88 Nonspecific lymphadenitis
0.643 0.357 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.643 0.357 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.643 0.357 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.642 0.358 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.641 0.358 0.000
Y44.2 Anticoagulants
0.641 0.359 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.640 0.359 0.000
T79-T79 Certain early complications of trauma
0.640 0.360 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.639 0.361 0.000
E04 Other non-toxic goitre
0.638 0.361 0.000
S52 Fracture of forearm
0.638 0.362 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.637 0.363 0.000
C09 Malignant neoplasm of tonsil
0.637 0.363 0.000
J95-J99 Other diseases of the respiratory system
0.636 0.363 0.000
D37.9 Digestive organ, unspecified
0.636 0.364 0.000
I42.8 Other cardiomyopathies
0.636 0.364 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.636 0.364 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.635 0.365 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.635 0.365 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.635 0.365 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.633 0.367 0.000
C65 Malignant neoplasm of renal pelvis
0.633 0.367 0.000
M45 Ankylosing spondylitis
0.632 0.368 0.000
S40-S49 Injuries to the shoulder and upper arm
0.632 0.368 0.000
G41.9 Status epilepticus, unspecified
0.632 0.368 0.000
Chapter I Certain infectious and parasitic diseases
0.632 0.368 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.631 0.368 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.632 0.368 0.000
I52 Other heart disorders in diseases classified elsewhere
0.631 0.369 0.000
I48 Atrial fibrillation and flutter
0.631 0.369 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.631 0.369 0.000
I41 Myocarditis in diseases classified elsewhere
0.631 0.369 0.000
I40 Acute myocarditis
0.631 0.369 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.631 0.369 0.000
I37 Pulmonary valve disorders
0.631 0.369 0.000
I36 Nonrheumatic tricuspid valve disorders
0.631 0.369 0.000
I32 Pericarditis in diseases classified elsewhere
0.631 0.369 0.000
R35 Polyuria
0.631 0.369 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.631 0.369 0.000
H90.3 Sensorineural hearing loss, bilateral
0.629 0.371 0.000
F41 Other anxiety disorders
0.629 0.371 0.000
H90.2 Conductive hearing loss, unspecified
0.629 0.371 0.000
R27 Other lack of coordination
0.628 0.372 0.000
G80 Infantile cerebral palsy
0.628 0.372 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.627 0.373 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.627 0.373 0.000
I74 Arterial embolism and thrombosis
0.627 0.373 0.000
E13 Other specified diabetes mellitus
0.626 0.374 0.000
G24 Dystonia
0.626 0.374 0.000
I70 Atherosclerosis
0.625 0.375 0.000
J90-J94 Other diseases of pleura
0.624 0.376 0.000
R76.8 Other specified abnormal immunological findings in serum
0.624 0.376 0.000
S90 Superficial injury of ankle and foot
0.624 0.376 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.624 0.376 0.000
I42.0 Dilated cardiomyopathy
0.623 0.377 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.622 0.378 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.622 0.378 0.000
C13 Malignant neoplasm of hypopharynx
0.622 0.378 0.000
C11 Malignant neoplasm of nasopharynx
0.622 0.378 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.622 0.378 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.622 0.378 0.000
C05 Malignant neoplasm of palate
0.622 0.378 0.000
C04 Malignant neoplasm of floor of mouth
0.622 0.378 0.000
C03 Malignant neoplasm of gum
0.622 0.378 0.000
C00 Malignant neoplasm of lip
0.622 0.378 0.000
C12 Malignant neoplasm of pyriform sinus
0.622 0.378 0.000
C07 Malignant neoplasm of parotid gland
0.622 0.378 0.000
R82 Other abnormal findings in urine
0.621 0.379 0.000
D22.5 Melanocytic naevi of trunk
0.621 0.379 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.620 0.380 0.000
W20-W49 Exposure to inanimate mechanical forces
0.620 0.380 0.000
D12.4 Descending colon
0.620 0.380 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.620 0.380 0.000
Y43.3 Other antineoplastic drugs
0.620 0.380 0.000
D86 Sarcoidosis
0.620 0.380 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.619 0.381 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.618 0.382 0.000
S80 Superficial injury of lower leg
0.618 0.382 0.000
F41.2 Mixed anxiety and depressive disorder
0.618 0.382 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.617 0.383 0.000
E50-E64 Other nutritional deficiencies
0.617 0.383 0.000
E20.9 Hypoparathyroidism, unspecified
0.617 0.383 0.000
I73.8 Other specified peripheral vascular diseases
0.617 0.383 0.000
S60-S69 Injuries to the wrist and hand
0.617 0.383 0.000
G11 Hereditary ataxia
0.616 0.384 0.000
I73.0 Raynaud's syndrome
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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