TreeWAS – Variant ID: rs7594983

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.939	0.061
E89.0 Postprocedural hypothyroidism	0.057	0.943	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.967	0.033
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.023	0.977	0.000
E89.2 Postprocedural hypoparathyroidism	0.020	0.980	0.000
C71 Malignant neoplasm of brain	0.000	0.981	0.019
C71.1 Frontal lobe	0.000	0.981	0.019
C71.9 Brain, unspecified	0.000	0.982	0.018
E89.1 Postprocedural hypoinsulinaemia	0.017	0.983	0.000
E80.4 Gilbert's syndrome	0.000	0.983	0.017
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.017	0.983	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.017	0.983	0.000
E89.5 Postprocedural testicular hypofunction	0.017	0.983	0.000
C71.2 Temporal lobe	0.000	0.983	0.017
C71.4 Occipital lobe	0.000	0.983	0.017
Z03.4 Observation for suspected myocardial infarction	0.000	0.984	0.016
E89.4 Postprocedural ovarian failure	0.015	0.985	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.015	0.985	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.985	0.015
C71.7 Brain stem	0.000	0.986	0.014
C71.6 Cerebellum	0.000	0.986	0.014
C71.5 Cerebral ventricle	0.000	0.986	0.014
C71.8 Overlapping lesion of brain	0.000	0.986	0.013
E89.3 Postprocedural hypopituitarism	0.013	0.986	0.000
C71.3 Parietal lobe	0.000	0.986	0.013
D05 Carcinoma in situ of breast	0.000	0.987	0.013
D23.5 Skin of trunk	0.012	0.988	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.989	0.011
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.989	0.011
D05.0 Lobular carcinoma in situ	0.000	0.989	0.011
L85.8 Other specified epidermal thickening	0.010	0.990	0.000
E80.1 Porphyria cutanea tarda	0.000	0.991	0.009
E80.2 Other porphyria	0.000	0.991	0.009
H33.2 Serous retinal detachment	0.009	0.991	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.992	0.008
E80.5 Crigler-Najjar syndrome	0.000	0.992	0.008
E80.3 Defects of catalase and peroxydase	0.000	0.992	0.008
E80.0 Hereditary erythropoietic porphyria	0.000	0.992	0.008
E80.6 Other disorders of bilirubin metabolism	0.000	0.992	0.008
M47.9 Spondylosis, unspecified	0.000	0.994	0.006
I27.0 Primary pulmonary hypertension	0.006	0.994	0.000
S92.30 Fracture of metatarsal bone (closed)	0.006	0.994	0.000
Z92.3 Personal history of irradiation	0.000	0.994	0.006
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.005	0.995	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.995	0.005
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.995	0.005
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.995	0.005
Z01.9 Special examination, unspecified	0.005	0.995	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.995	0.005
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.995	0.005
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.995	0.005
M79.00 Rheumatism, unspecified (Multiple sites)	0.005	0.995	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.996	0.004
N60.3 Fibrosclerosis of breast	0.000	0.996	0.004
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M79.0 Rheumatism, unspecified	0.004	0.996	0.000
C70 Malignant neoplasm of meninges	0.000	0.996	0.004
M79.09 Rheumatism, unspecified (Site unspecified)	0.004	0.996	0.000
M82.1 Osteoporosis in endocrine disorders	0.004	0.996	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.996	0.004
E16.1 Other hypoglycaemia	0.000	0.996	0.004
M79.08 Rheumatism, unspecified (Other)	0.004	0.996	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.004	0.996	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.004	0.996	0.000
E06.3 Autoimmune thyroiditis	0.004	0.996	0.000
R44.3 Hallucinations, unspecified	0.000	0.996	0.004
C69.9 Eye, unspecified	0.000	0.996	0.004
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.004	0.996	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.003	0.996	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.996	0.003
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
C69.0 Conjunctiva	0.000	0.997	0.003
E16.2 Hypoglycaemia, unspecified	0.000	0.997	0.003
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
M79.07 Rheumatism, unspecified (Ankle and foot)	0.003	0.997	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M79.04 Rheumatism, unspecified (Hand)	0.003	0.997	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.003	0.997	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.003	0.997	0.000
C70.9 Meninges, unspecified	0.000	0.997	0.003
C70.1 Spinal meninges	0.000	0.997	0.003
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.003	0.997	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.003	0.997	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.003	0.997	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.003	0.997	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.003	0.997	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.003	0.997	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.003	0.997	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.997	0.003
C69.5 Lachrymal gland and duct	0.000	0.997	0.003
C69.4 Ciliary body	0.000	0.997	0.003
C69.1 Cornea	0.000	0.997	0.003
Q63.0 Accessory kidney	0.003	0.997	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.997	0.003
M79.01 Rheumatism, unspecified (Shoulder region)	0.003	0.997	0.000
C70.0 Cerebral meninges	0.000	0.997	0.003
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
C69.2 Retina	0.000	0.997	0.003
L85 Other epidermal thickening	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
C72.9 Central nervous system, unspecified	0.000	0.997	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.997	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.997	0.002
C72.4 Acoustic nerve	0.000	0.997	0.002
C72.3 Optic nerve	0.000	0.997	0.002
C72.2 Olfactory nerve	0.000	0.997	0.002
C72.1 Cauda equina	0.000	0.997	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.997	0.003
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.997	0.003
E16.4 Abnormal secretion of gastrin	0.000	0.997	0.003
E16.3 Increased secretion of glucagon	0.000	0.997	0.003
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.002	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
C69.6 Orbit	0.000	0.997	0.002
K82.1 Hydrops of gallbladder	0.003	0.997	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.997	0.003
R44.2 Other hallucinations	0.000	0.997	0.002
E06.5 Other chronic thyroiditis	0.002	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
R45.4 Irritability and anger	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
L85.3 Xerosis cutis	0.002	0.998	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.002	0.998	0.000
L85.0 Acquired ichthyosis	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
C72.0 Spinal cord	0.001	0.998	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
J32.9 Chronic sinusitis, unspecified	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
R45.5 Hostility	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.000	0.998	0.002
Y83.4 Other reconstructive surgery	0.002	0.998	0.000
G11 Hereditary ataxia	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.002	0.998	0.000
R45.6 Physical violence	0.000	0.998	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
R45.2 Unhappiness	0.000	0.998	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.000	0.998	0.002
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
R45.0 Nervousness	0.000	0.998	0.002
E20 Hypoparathyroidism	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.002	0.998	0.000
R45.3 Demoralisation and apathy	0.000	0.998	0.002
J32.1 Chronic frontal sinusitis	0.000	0.998	0.002
G11.8 Other hereditary ataxias	0.000	0.998	0.002
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.998	0.002
G11.2 Late-onset cerebellar ataxia	0.000	0.998	0.002
G11.0 Congenital nonprogressive ataxia	0.000	0.998	0.002
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
R46.4 Slowness and poor responsiveness	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.000	0.998	0.002
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
D13.5 Extrahepatic bile ducts	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.000	0.998	0.001
H18 Other disorders of cornea	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.998	0.002
R46 Symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.001
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.001
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.000	0.998	0.002
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
J35.0 Chronic tonsillitis	0.000	0.998	0.002
E34 Other endocrine disorders	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.001
E28.8 Other ovarian dysfunction	0.000	0.998	0.001
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.001
E28.0 Oestrogen excess	0.000	0.998	0.001
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
G11.4 Hereditary spastic paraplegia	0.000	0.998	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.002
E87.2 Acidosis	0.000	0.998	0.002
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
K27.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.000	0.998	0.002
M13.97 Arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.001
R46.0 Very low level of personal hygiene	0.000	0.998	0.001
M11.29 Other chondrocalcinosis (Site unspecified)	0.001	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.001	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.001	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.001	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.001	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.001	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.001	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.002
H18.4 Corneal degeneration	0.001	0.998	0.000
J32.4 Chronic pansinusitis	0.000	0.998	0.001
O44.0 Placenta praevia specified as without haemorrhage	0.001	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.001
S20.2 Contusion of thorax	0.001	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.000	0.998	0.001
H18.2 Other corneal oedema	0.001	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.001
S20 Superficial injury of thorax	0.001	0.998	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.999	0.001
R46.6 Undue concern and preoccupation with stressful events	0.000	0.999	0.001
R46.5 Suspiciousness and marked evasiveness	0.000	0.999	0.001
R46.3 Overactivity	0.000	0.999	0.001
R46.1 Bizarre personal appearance	0.000	0.999	0.001
S20.3 Other superficial injuries of front wall of thorax	0.001	0.999	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.999	0.001
E29 Testicular dysfunction	0.000	0.999	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.999	0.001
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
N30.8 Other cystitis	0.001	0.999	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.999	0.001
D13.2 Duodenum	0.000	0.999	0.001
E34.5 Androgen resistance syndrome	0.000	0.999	0.001
E34.4 Constitutional tall stature	0.000	0.999	0.001
E34.3 Short stature, not elsewhere classified	0.000	0.999	0.001
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.999	0.001
E34.1 Other hypersecretion of intestinal hormones	0.000	0.999	0.001
H18.6 Keratoconus	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.999	0.001
H11.9 Disorder of conjunctiva, unspecified	0.000	0.999	0.001
S92.7 Multiple fractures of foot	0.001	0.999	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.999	0.001
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.999	0.001
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.999	0.001
M77.91 Enthesopathy, unspecified (Shoulder region)	0.001	0.999	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.999	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.999	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.999	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.999	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.999	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.999	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.999	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.999	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.999	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.999	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.999	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
R46.2 Strange and inexplicable behaviour	0.000	0.999	0.001
T39.0 Salicylates	0.000	0.999	0.001
J32 Chronic sinusitis	0.000	0.999	0.001
D13.9 Ill-defined sites within the digestive system	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.000	0.999	0.001
I27.8 Other specified pulmonary heart diseases	0.001	0.999	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999	0.000
M91.20 Coxa plana-Mult sites	0.000	0.999	0.001
F52.2 Failure of genital response	0.000	0.999	0.001
K85.2 Alcohol-induced acute pancreatitis	0.000	0.999	0.001
L29.2 Pruritus vulvae	0.001	0.999	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.001	0.999	0.000
D26.0 Cervix uteri	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
F17.2 Dependence syndrome	0.000	0.999	0.001
S20.7 Multiple superficial injuries of thorax	0.001	0.999	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.999	0.001
E29.8 Other testicular dysfunction	0.000	0.999	0.001
E29.0 Testicular hyperfunction	0.000	0.999	0.001
H11.2 Conjunctival scars	0.000	0.999	0.001
N76.8 Other specified inflammation of vagina and vulva	0.000	0.999	0.001
Q61.5 Medullary cystic kidney	0.001	0.999	0.000
R30.0 Dysuria	0.000	0.999	0.001
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.999	0.001
T90.4 Sequelae of injury of eye and orbit	0.001	0.999	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.999	0.001
Z01.7 Laboratory examination	0.001	0.999	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.999	0.001
E32 Diseases of thymus	0.000	0.999	0.001
E31 Polyglandular dysfunction	0.000	0.999	0.001
E30 Disorders of puberty, not elsewhere classified	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
J32.8 Other chronic sinusitis	0.000	0.999	0.001
Z01.4 Gynaecological examination (general)(routine)	0.001	0.999	0.000
E25 Adrenogenital disorders	0.000	0.999	0.001
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.999	0.001
S82.10 Fracture of upper end of tibia (closed)	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.999	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.999	0.001
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.999	0.001
Q64 Other congenital malformations of urinary system	0.001	0.999	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
H18.9 Disorder of cornea, unspecified	0.001	0.999	0.000
S20.4 Other superficial injuries of back wall of thorax	0.001	0.999	0.000
Z01.2 Dental examination	0.001	0.999	0.000
R42 Dizziness and giddiness	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.999	0.001
E26.9 Hyperaldosteronism, unspecified	0.000	0.999	0.001
H26.8 Other specified cataract	0.001	0.999	0.000
J86.0 Pyothorax with fistula	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.999	0.001
S92.11 Fracture of talus (open)	0.001	0.999	0.000
I07.1 Tricuspid insufficiency	0.000	0.999	0.001
S20.0 Contusion of breast	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
E26 Hyperaldosteronism	0.000	0.999	0.001
Q61 Cystic kidney disease	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.999	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.999	0.001
E25.8 Other adrenogenital disorders	0.000	0.999	0.001
E30.9 Disorder of puberty, unspecified	0.000	0.999	0.001
E30.8 Other disorders of puberty	0.000	0.999	0.001
E30.1 Precocious puberty	0.000	0.999	0.001
E30.0 Delayed puberty	0.000	0.999	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.999	0.001
E31.8 Other polyglandular dysfunction	0.000	0.999	0.001
E31.1 Polyglandular hyperfunction	0.000	0.999	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.999	0.001
E32.9 Disease of thymus, unspecified	0.000	0.999	0.001
E32.8 Other diseases of thymus	0.000	0.999	0.001
E32.1 Abscess of thymus	0.000	0.999	0.001
E32.0 Persistent hyperplasia of thymus	0.000	0.999	0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.999	0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.999	0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.999	0.001
I70.1 Atherosclerosis of renal artery	0.000	0.999	0.001
J38.4 Oedema of larynx	0.000	0.999	0.001
Q62.2 Congenital megaloureter	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
D13.7 Endocrine pancreas	0.000	0.999	0.001
D13.6 Pancreas	0.000	0.999	0.001
D13.3 Other and unspecified parts of small intestine	0.000	0.999	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.999	0.001
Q62.8 Other congenital malformations of ureter	0.001	0.999	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.999	0.000
Q62.6 Malposition of ureter	0.001	0.999	0.000
Q62.5 Duplication of ureter	0.001	0.999	0.000
Q62.4 Agenesis of ureter	0.001	0.999	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.999	0.000
Q62.0 Congenital hydronephrosis	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.999	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.999	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.999	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.001	0.999	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.999	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.999	0.000
Q64.0 Epispadias	0.001	0.999	0.000
S20.1 Other and unspecified superficial injuries of breast	0.001	0.999	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.000	0.999	0.001
M70.32 Other bursitis of elbow-Upper arm	0.000	0.999	0.001
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
O36.6 Maternal care for excessive foetal growth	0.001	0.999	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.999	0.000
Q61.9 Cystic kidney disease, unspecified	0.001	0.999	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.999	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.999	0.001
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.999	0.001
E88.2 Lipomatosis, not elsewhere classified	0.000	0.999	0.001
G12.2 Motor neuron disease	0.000	0.999	0.001
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
N60.0 Solitary cyst of breast	0.000	0.999	0.001
O41.0 Oligohydramnios	0.000	0.999	0.001
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.999	0.001
D13.4 Liver	0.000	0.999	0.001
E26.8 Other hyperaldosteronism	0.000	0.999	0.001
E26.1 Secondary hyperaldosteronism	0.000	0.999	0.001
Q61.8 Other cystic kidney diseases	0.001	0.999	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.999	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.999	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.999	0.001
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.999	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
E27.2 Addisonian crisis	0.000	0.999	0.001
E85.9 Amyloidosis, unspecified	0.000	0.999	0.001
I70.8 Atherosclerosis of other arteries	0.000	0.999	0.001
Q60.6 Potter's syndrome	0.001	0.999	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.999	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.999	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.999	0.000
R43.2 Parageusia	0.000	0.999	0.001
E27 Other disorders of adrenal gland	0.000	0.999	0.001
E22 Hyperfunction of pituitary gland	0.000	0.999	0.001
G12 Spinal muscular atrophy and related syndromes	0.000	0.999	0.001
R43 Disturbances of smell and taste	0.000	0.999	0.001
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.001	0.999	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.999	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.999	0.001
J35.2 Hypertrophy of adenoids	0.000	0.999	0.001
J38.1 Polyp of vocal cord and larynx	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
Z01.3 Examination of blood pressure	0.001	0.999	0.000
D24 Benign neoplasm of breast	0.000	0.999	0.001
I70 Atherosclerosis	0.000	0.999	0.001
J35 Chronic diseases of tonsils and adenoids	0.000	0.999	0.001
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.999	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.999	0.001
E88.9 Metabolic disorder, unspecified	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
R06.0 Dyspnoea	0.000	0.999	0.001
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.999	0.001
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.999	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.999	0.001
E27.5 Adrenomedullary hyperfunction	0.000	0.999	0.001
E27.0 Other adrenocortical overactivity	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.000	0.999	0.001
G12.9 Spinal muscular atrophy, unspecified	0.000	0.999	0.001
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.999	0.001
G12.1 Other inherited spinal muscular atrophy	0.000	0.999	0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.999	0.001
I70.9 Generalised and unspecified atherosclerosis	0.000	0.999	0.001
J32.3 Chronic sphenoidal sinusitis	0.000	0.999	0.001
J69.0 Pneumonitis due to food and vomit	0.000	0.999	0.001
M87.9 Osteonecrosis, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations