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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76114334
log Bayes Factor = 19.0254
Chromosome 16   position 83,093,295  (GRCh37) Explore rs76114334 on Ensembl!
Variant rs76114334 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.992 0.008 0.000
I25.1 Atherosclerotic heart disease
0.990 0.010 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.978 0.022 0.000
J30-J39 Other diseases of upper respiratory tract
0.975 0.025 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.969 0.031 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.965 0.035 0.000
Z95.1 Presence of aortocoronary bypass graft
0.964 0.036 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.960 0.040 0.000
Y83.6 Removal of other organ (partial) (total)
0.951 0.049 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.951 0.049 0.000
I20 Angina pectoris
0.949 0.051 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.944 0.056 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.944 0.056 0.000
O60-O75 Complications of labour and delivery
0.942 0.058 0.000
J09-J18 Influenza and pneumonia
0.942 0.058 0.000
I30-I52 Other forms of heart disease
0.942 0.058 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.936 0.064 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.932 0.068 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.928 0.072 0.000
E78.5 Hyperlipidaemia, unspecified
0.927 0.073 0.000
M05-M14 Inflammatory polyarthropathies
0.925 0.075 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.923 0.077 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.921 0.079 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.918 0.082 0.000
Chapter XIV Diseases of the genitourinary system
0.917 0.083 0.000
I60-I69 Cerebrovascular diseases
0.909 0.091 0.000
E86 Volume depletion
0.908 0.092 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.907 0.093 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.906 0.094 0.000
Z95.4 Presence of other heart-valve replacement
0.906 0.094 0.000
M06 Other rheumatoid arthritis
0.901 0.099 0.000
Chapter VIII Diseases of the ear and mastoid process
0.899 0.101 0.000
J18 Pneumonia, organism unspecified
0.899 0.101 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.896 0.104 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.896 0.104 0.000
Chapter XI Diseases of the digestive system
0.894 0.106 0.000
I20.9 Angina pectoris, unspecified
0.893 0.107 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.893 0.107 0.000
I21 Acute myocardial infarction
0.884 0.116 0.000
G62 Other polyneuropathies
0.882 0.118 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.881 0.119 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.880 0.120 0.000
L60-L75 Disorders of skin appendages
0.880 0.120 0.000
J18.9 Pneumonia, unspecified
0.878 0.122 0.000
M06.9 Rheumatoid arthritis, unspecified
0.876 0.124 0.000
Y83.4 Other reconstructive surgery
0.876 0.124 0.000
E83 Disorders of mineral metabolism
0.876 0.124 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.875 0.125 0.000
N17-N19 Renal failure
0.875 0.125 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.875 0.125 0.000
I67 Other cerebrovascular diseases
0.868 0.132 0.000
S00-S09 Injuries to the head
0.860 0.140 0.000
G40-G47 Episodic and paroxysmal disorders
0.860 0.140 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.859 0.141 0.000
M45-M49 Spondylopathies
0.858 0.142 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.856 0.144 0.000
O00-O08 Pregnancy with abortive outcome
0.853 0.147 0.000
O70 Perineal laceration during delivery
0.853 0.147 0.000
G62.9 Polyneuropathy, unspecified
0.852 0.148 0.000
I05-I09 Chronic rheumatic heart diseases
0.851 0.149 0.000
Z93 Artificial opening status
0.849 0.151 0.000
I10-I15 Hypertensive diseases
0.849 0.151 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.848 0.152 0.000
R47-R49 Symptoms and signs involving speech and voice
0.844 0.156 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.844 0.156 0.000
M10 Gout
0.842 0.158 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.840 0.160 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.840 0.160 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.839 0.161 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.837 0.163 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.836 0.164 0.000
I50 Heart failure
0.836 0.164 0.000
I25.2 Old myocardial infarction
0.834 0.166 0.000
S60-S69 Injuries to the wrist and hand
0.831 0.169 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.830 0.170 0.000
I49 Other cardiac arrhythmias
0.829 0.171 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.829 0.171 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.829 0.171 0.000
J60-J70 Lung diseases due to external agents
0.828 0.172 0.000
O47 False labour
0.828 0.172 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.828 0.172 0.000
Z95.0 Presence of cardiac pacemaker
0.826 0.174 0.000
J34 Other disorders of nose and nasal sinuses
0.825 0.175 0.000
S40-S49 Injuries to the shoulder and upper arm
0.824 0.176 0.000
E89.0 Postprocedural hypothyroidism
0.823 0.177 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.823 0.177 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.821 0.179 0.000
I35 Nonrheumatic aortic valve disorders
0.819 0.181 0.000
I25.3 Aneurysm of heart
0.819 0.181 0.000
E10-E14 Diabetes mellitus
0.818 0.182 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.818 0.182 0.000
Y83.9 Surgical procedure, unspecified
0.818 0.182 0.000
J30 Vasomotor and allergic rhinitis
0.815 0.185 0.000
W20-W49 Exposure to inanimate mechanical forces
0.814 0.186 0.000
M47 Spondylosis
0.814 0.186 0.000
N18 Chronic renal failure
0.814 0.186 0.000
J32 Chronic sinusitis
0.813 0.187 0.000
J31.0 Chronic rhinitis
0.812 0.188 0.000
K90-K93 Other diseases of the digestive system
0.810 0.190 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.810 0.190 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.808 0.192 0.000
S70-S79 Injuries to the hip and thigh
0.808 0.192 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.807 0.193 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.806 0.194 0.000
S20-S29 Injuries to the thorax
0.806 0.194 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.805 0.195 0.000
K26 Duodenal ulcer
0.805 0.195 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.805 0.195 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.802 0.198 0.000
Z80 Family history of malignant neoplasm
0.802 0.198 0.000
N40-N51 Diseases of male genital organs
0.801 0.199 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.801 0.199 0.000
N10-N16 Renal tubulo-interstitial diseases
0.800 0.200 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.799 0.201 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.799 0.201 0.000
M47.8 Other spondylosis
0.797 0.203 0.000
H60-H62 Diseases of external ear
0.796 0.204 0.000
I71 Aortic aneurysm and dissection
0.794 0.206 0.000
V80-V89 Other land transport accidents
0.794 0.206 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.793 0.207 0.000
Z95.2 Presence of prosthetic heart valve
0.791 0.209 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.790 0.210 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.790 0.210 0.000
Chapter I Certain infectious and parasitic diseases
0.787 0.213 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.787 0.213 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.784 0.216 0.000
M10.9 Gout, unspecified
0.783 0.217 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.780 0.220 0.000
I50.1 Left ventricular failure
0.778 0.222 0.000
E83.5 Disorders of calcium metabolism
0.778 0.222 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.777 0.223 0.000
E87.6 Hypokalaemia
0.776 0.224 0.000
I67.8 Other specified cerebrovascular diseases
0.776 0.224 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.775 0.225 0.000
E20-E35 Disorders of other endocrine glands
0.775 0.225 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.775 0.225 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.775 0.225 0.000
I22 Subsequent myocardial infarction
0.773 0.227 0.000
T81 Complications of procedures, not elsewhere classified
0.771 0.229 0.000
Y84.8 Other medical procedures
0.771 0.229 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.770 0.230 0.000
J39 Other diseases of upper respiratory tract
0.769 0.231 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.768 0.232 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.766 0.234 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.766 0.234 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.765 0.235 0.000
I20.0 Unstable angina
0.764 0.236 0.000
I25.5 Ischaemic cardiomyopathy
0.762 0.238 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.761 0.239 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.759 0.241 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.758 0.242 0.000
N17 Acute renal failure
0.758 0.242 0.000
O63 Long labour
0.757 0.243 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.757 0.243 0.000
K20 Oesophagitis
0.755 0.245 0.000
K22 Other diseases of oesophagus
0.755 0.245 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.754 0.246 0.000
J95-J99 Other diseases of the respiratory system
0.753 0.247 0.000
I08 Multiple valve diseases
0.753 0.247 0.000
J90-J94 Other diseases of pleura
0.753 0.247 0.000
I51 Complications and ill-defined descriptions of heart disease
0.752 0.248 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.751 0.249 0.000
M07 Psoriatic and enteropathic arthropathies
0.751 0.249 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.250 0.000
S80-S89 Injuries to the knee and lower leg
0.747 0.253 0.000
O73 Retained placenta and membranes, without haemorrhage
0.746 0.254 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.746 0.254 0.000
O02 Other abnormal products of conception
0.745 0.255 0.000
R47 Speech disturbances, not elsewhere classified
0.744 0.256 0.000
O70.1 Second degree perineal laceration during delivery
0.744 0.256 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.744 0.256 0.000
E10 Insulin-dependent diabetes mellitus
0.743 0.257 0.000
I67.9 Cerebrovascular disease, unspecified
0.742 0.258 0.000
M10.99 Gout, unspecified (Site unspecified)
0.741 0.259 0.000
I34 Nonrheumatic mitral valve disorders
0.741 0.259 0.000
N60-N64 Disorders of breast
0.740 0.260 0.000
I69 Sequelae of cerebrovascular disease
0.740 0.260 0.000
M47.86 Other spondylosis (Lumbar region)
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.740 0.260 0.000
K70-K77 Diseases of liver
0.738 0.262 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.737 0.263 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.737 0.263 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.735 0.265 0.000
O32.1 Maternal care for breech presentation
0.732 0.268 0.000
N20-N23 Urolithiasis
0.731 0.269 0.000
K92 Other diseases of digestive system
0.730 0.270 0.000
T82.1 Mechanical complication of cardiac electronic device
0.729 0.271 0.000
O72 Postpartum haemorrhage
0.727 0.272 0.000
Y84.0 Cardiac catheterisation
0.727 0.273 0.000
M06.0 Seronegative rheumatoid arthritis
0.726 0.274 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.725 0.275 0.000
I99 Other and unspecified disorders of circulatory system
0.724 0.275 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.724 0.276 0.000
Z99.2 Dependence on renal dialysis
0.722 0.278 0.000
L71 Rosacea
0.718 0.282 0.000
I10 Essential (primary) hypertension
0.718 0.282 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M86-M90 Other osteopathies
0.716 0.283 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.716 0.284 0.000
Z94 Transplanted organ and tissue status
0.715 0.284 0.000
E88 Other metabolic disorders
0.715 0.285 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
J34.2 Deviated nasal septum
0.714 0.285 0.000
R41.0 Disorientation, unspecified
0.714 0.286 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.713 0.287 0.000
I49.3 Ventricular premature depolarisation
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.712 0.288 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.711 0.289 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.711 0.289 0.000
O70.0 First degree perineal laceration during delivery
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.710 0.290 0.000
J69 Pneumonitis due to solids and liquids
0.709 0.291 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.709 0.291 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.709 0.291 0.000
M47.82 Other spondylosis (Cervical region)
0.708 0.292 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
H61 Other disorders of external ear
0.708 0.292 0.000
G45.3 Amaurosis fugax
0.708 0.292 0.000
I74 Arterial embolism and thrombosis
0.707 0.293 0.000
Y83.5 Amputation of limb(s)
0.705 0.295 0.000
Y83.0 Surgical operation with transplant of whole organ
0.705 0.295 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.705 0.295 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.705 0.295 0.000
N13 Obstructive and reflux uropathy
0.705 0.295 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.704 0.296 0.000
L90 Atrophic disorders of skin
0.703 0.297 0.000
J18.0 Bronchopneumonia, unspecified
0.703 0.297 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
T66-T78 Other and unspecified effects of external causes
0.701 0.299 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.700 0.299 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.700 0.300 0.000
K22.2 Oesophageal obstruction
0.700 0.300 0.000
I35.0 Aortic (valve) stenosis
0.700 0.300 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.700 0.300 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.700 0.300 0.000
Chapter V Mental and behavioural disorders
0.700 0.300 0.000
J37 Chronic laryngitis and laryngotracheitis
0.699 0.301 0.000
S02 Fracture of skull and facial bones
0.698 0.302 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.697 0.303 0.000
I67.2 Cerebral atherosclerosis
0.697 0.303 0.000
K26.3 Acute without haemorrhage or perforation
0.696 0.304 0.000
I20.8 Other forms of angina pectoris
0.695 0.305 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.695 0.305 0.000
Z95.3 Presence of xenogenic heart valve
0.695 0.305 0.000
G70-G73 Diseases of myoneural junction and muscle
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.305 0.000
J32.9 Chronic sinusitis, unspecified
0.694 0.306 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.693 0.307 0.000
Z01.6 Radiological examination, not elsewhere classified
0.693 0.307 0.000
J35 Chronic diseases of tonsils and adenoids
0.693 0.307 0.000
T92 Sequelae of injuries of upper limb
0.693 0.307 0.000
Z89 Acquired absence of limb
0.692 0.308 0.000
Z84 Family history of other conditions
0.692 0.308 0.000
Z81 Family history of mental and behavioural disorders
0.692 0.308 0.000
H90-H95 Other disorders of ear
0.692 0.308 0.000
S01 Open wound of head
0.691 0.309 0.000
Z93.2 Ileostomy status
0.689 0.311 0.000
I31 Other diseases of pericardium
0.689 0.311 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.689 0.311 0.000
L82 Seborrhoeic keratosis
0.689 0.311 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.689 0.311 0.000
E78.8 Other disorders of lipoprotein metabolism
0.688 0.312 0.000
E78.6 Lipoprotein deficiency
0.688 0.312 0.000
E78.4 Other hyperlipidaemia
0.688 0.312 0.000
E78.3 Hyperchylomicronaemia
0.688 0.312 0.000
E78.2 Mixed hyperlipidaemia
0.688 0.312 0.000
E78.1 Pure hyperglyceridaemia
0.688 0.312 0.000
E50-E64 Other nutritional deficiencies
0.688 0.312 0.000
Z99.3 Dependence on wheelchair
0.687 0.313 0.000
N18.2 Chronic kidney disease, stage 2
0.687 0.313 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.687 0.313 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.686 0.314 0.000
I21.4 Acute subendocardial myocardial infarction
0.686 0.314 0.000
Z97 Presence of other devices
0.686 0.314 0.000
R49 Voice disturbances
0.686 0.314 0.000
L91 Hypertrophic disorders of skin
0.685 0.315 0.000
L81 Other disorders of pigmentation
0.684 0.316 0.000
K83 Other diseases of biliary tract
0.684 0.316 0.000
M80-M85 Disorders of bone density and structure
0.683 0.317 0.000
W00-W19 Falls
0.683 0.317 0.000
G20-G26 Extrapyramidal and movement disorders
0.683 0.317 0.000
L10-L14 Bullous disorders
0.682 0.318 0.000
L20-L30 Dermatitis and eczema
0.681 0.318 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.680 0.319 0.000
I20.1 Angina pectoris with documented spasm
0.680 0.319 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.680 0.320 0.000
E83.4 Disorders of magnesium metabolism
0.680 0.320 0.000
I95 Hypotension
0.680 0.320 0.000
O00 Ectopic pregnancy
0.679 0.321 0.000
T90 Sequelae of injuries of head
0.679 0.321 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.679 0.321 0.000
K92.1 Melaena
0.678 0.322 0.000
Z12 Special screening examination for neoplasms
0.678 0.322 0.000
O45 Premature separation of placenta [abruptio placentae]
0.677 0.323 0.000
O44 Placenta praevia
0.677 0.323 0.000
O43 Placental disorders
0.677 0.323 0.000
O41 Other disorders of amniotic fluid and membranes
0.677 0.323 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.677 0.323 0.000
O33 Maternal care for known or suspected disproportion
0.677 0.323 0.000
O31 Complications specific to multiple gestation
0.677 0.323 0.000
O30 Multiple gestation
0.677 0.323 0.000
O40 Polyhydramnios
0.677 0.323 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.677 0.323 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.676 0.324 0.000
M50-M54 Other dorsopathies
0.676 0.324 0.000
I70 Atherosclerosis
0.676 0.324 0.000
O80-O84 Delivery
0.675 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.675 0.324 0.000
O71 Other obstetric trauma
0.675 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.675 0.324 0.000
O66 Other obstructed labour
0.675 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.675 0.324 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.675 0.324 0.000
O62 Abnormalities of forces of labour
0.675 0.324 0.000
O61 Failed induction of labour
0.675 0.324 0.000
O60 Preterm delivery
0.675 0.324 0.000
J17 Pneumonia in diseases classified elsewhere
0.675 0.324 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.675 0.324 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.675 0.324 0.000
J12 Viral pneumonia, not elsewhere classified
0.675 0.324 0.000
J11 Influenza, virus not identified
0.675 0.324 0.000
J10 Influenza due to identified influenza virus
0.675 0.324 0.000
J14 Pneumonia due to Haemophilus influenzae
0.675 0.324 0.000
J09 Influenza due to certain identified influenza virus
0.675 0.324 0.000
E10.9 Without complications
0.675 0.325 0.000
I52 Other heart disorders in diseases classified elsewhere
0.675 0.325 0.000
I48 Atrial fibrillation and flutter
0.675 0.325 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.675 0.325 0.000
I41 Myocarditis in diseases classified elsewhere
0.675 0.325 0.000
I40 Acute myocarditis
0.675 0.325 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.675 0.325 0.000
I37 Pulmonary valve disorders
0.675 0.325 0.000
I36 Nonrheumatic tricuspid valve disorders
0.675 0.325 0.000
I33 Acute and subacute endocarditis
0.675 0.325 0.000
I32 Pericarditis in diseases classified elsewhere
0.675 0.325 0.000
I30 Acute pericarditis
0.675 0.325 0.000
I38 Endocarditis, valve unspecified
0.675 0.325 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.674 0.326 0.000
N17.9 Acute renal failure, unspecified
0.674 0.326 0.000
N45 Orchitis and epididymitis
0.674 0.326 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.673 0.326 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.673 0.327 0.000
N25-N29 Other disorders of kidney and ureter
0.673 0.327 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.672 0.328 0.000
I24 Other acute ischaemic heart diseases
0.671 0.328 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.671 0.329 0.000
S72 Fracture of femur
0.670 0.330 0.000
O42 Premature rupture of membranes
0.670 0.330 0.000
L89 Decubitus ulcer
0.670 0.330 0.000
V10-V19 Pedal cyclist injured in transport accident
0.668 0.331 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.331 0.000
M60-M63 Disorders of muscles
0.668 0.331 0.000
M00-M03 Infectious arthropathies
0.668 0.331 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.668 0.332 0.000
Z93.5 Cystostomy status
0.668 0.332 0.000
K81 Cholecystitis
0.668 0.332 0.000
Z93.3 Colostomy status
0.668 0.332 0.000
H80-H83 Diseases of inner ear
0.668 0.332 0.000
O02.1 Missed abortion
0.667 0.333 0.000
B95-B98 Bacterial, viral and other infectious agents
0.666 0.334 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.665 0.334 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.665 0.334 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.665 0.334 0.000
T82.3 Mechanical complication of other vascular grafts
0.665 0.334 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.665 0.334 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.665 0.334 0.000
L72.1 Trichilemmal cyst
0.666 0.334 0.000
I77 Other disorders of arteries and arterioles
0.665 0.335 0.000
I51.7 Cardiomegaly
0.664 0.336 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.664 0.336 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.663 0.336 0.000
M11 Other crystal arthropathies
0.663 0.337 0.000
M14 Arthropathies in other diseases classified elsewhere
0.663 0.337 0.000
M12 Other specific arthropathies
0.663 0.337 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.663 0.337 0.000
M08 Juvenile arthritis
0.663 0.337 0.000
O36.8 Maternal care for other specified foetal problems
0.663 0.337 0.000
J30.1 Allergic rhinitis due to pollen
0.662 0.338 0.000
N18.5 Chronic kidney disease, stage 5
0.662 0.338 0.000
G61 Inflammatory polyneuropathy
0.662 0.338 0.000
G60 Hereditary and idiopathic neuropathy
0.662 0.338 0.000
G64 Other disorders of peripheral nervous system
0.662 0.338 0.000
S62 Fracture at wrist and hand level
0.662 0.338 0.000
I49.8 Other specified cardiac arrhythmias
0.660 0.340 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.660 0.340 0.000
N18.3 Chronic kidney disease, stage 3
0.660 0.340 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.660 0.340 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.659 0.340 0.000
Y84.6 Urinary catheterisation
0.659 0.341 0.000
H65-H75 Diseases of middle ear and mastoid
0.659 0.341 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.658 0.342 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.658 0.342 0.000
T85.2 Mechanical complication of intraocular lens
0.658 0.342 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.658 0.342 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.658 0.342 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
N42 Other disorders of prostate
0.655 0.345 0.000
Z99.1 Dependence on respirator
0.655 0.345 0.000
K27 Peptic ulcer, site unspecified
0.653 0.347 0.000
L73 Other follicular disorders
0.653 0.347 0.000
N99-N99 Other disorders of the genitourinary system
0.653 0.347 0.000
I27 Other pulmonary heart diseases
0.652 0.348 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.652 0.348 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.651 0.348 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.651 0.348 0.000
I62 Other nontraumatic intracranial haemorrhage
0.651 0.348 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.650 0.350 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.650 0.350 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.650 0.350 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.650 0.350 0.000
I12 Hypertensive renal disease
0.650 0.350 0.000
I67.1 Cerebral aneurysm, nonruptured
0.650 0.350 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.650 0.350 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.650 0.350 0.000
E87.4 Mixed disorder of acid-base balance
0.650 0.350 0.000
E87.3 Alkalosis
0.650 0.350 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.650 0.350 0.000
T88.4 Failed or difficult intubation
0.649 0.350 0.000
R40 Somnolence, stupor and coma
0.649 0.351 0.000
R47.1 Dysarthria and anarthria
0.649 0.351 0.000
W25 Contact with sharp glass
0.648 0.352 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.648 0.352 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.648 0.352 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.647 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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