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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76191003
log Bayes Factor = 9.4885
Chromosome 12   position 47,182,531  (GRCh37) Explore rs76191003 on Ensembl!
Variant rs76191003 is part of Cluster X0076

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
C79 Secondary malignant neoplasm of other sites
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
M06.9 Rheumatoid arthritis, unspecified
0.996 0.004 0.000
M86-M90 Other osteopathies
0.993 0.007 0.000
C78.2 Secondary malignant neoplasm of pleura
0.993 0.007 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.992 0.008 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.992 0.008 0.000
C50-C50 Malignant neoplasm of breast
0.988 0.012 0.000
C50 Malignant neoplasm of breast
0.980 0.020 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.977 0.023 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.967 0.033 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.967 0.033 0.000
S90-S99 Injuries to the ankle and foot
0.965 0.035 0.000
Chapter XXI Factors influencing health status and contact with health services
0.963 0.037 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.960 0.040 0.000
M89 Other disorders of bone
0.959 0.041 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.958 0.042 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.958 0.042 0.000
C64-C68 Malignant neoplasms of urinary tract
0.957 0.043 0.000
Z51 Other medical care
0.956 0.044 0.000
S50-S59 Injuries to the elbow and forearm
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.954 0.046 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.950 0.050 0.000
M20-M25 Other joint disorders
0.950 0.050 0.000
C50.9 Breast, unspecified
0.947 0.053 0.000
D80-D89 Certain disorders involving the immune mechanism
0.939 0.061 0.000
C67 Malignant neoplasm of bladder
0.934 0.066 0.000
Z51.1 Chemotherapy session for neoplasm
0.933 0.067 0.000
Z45 Adjustment and management of implanted device
0.932 0.068 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.931 0.069 0.000
D68 Other coagulation defects
0.929 0.071 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.929 0.071 0.000
Z51.3 Blood transfusion without reported diagnosis
0.928 0.072 0.000
D70 Agranulocytosis
0.920 0.080 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.919 0.081 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.919 0.081 0.000
C67.9 Bladder, unspecified
0.916 0.084 0.000
D69 Purpura and other haemorrhagic conditions
0.914 0.086 0.000
M90 Osteopathies in diseases classified elsewhere
0.911 0.089 0.000
M05 Seropositive rheumatoid arthritis
0.910 0.090 0.000
C50.2 Upper-inner quadrant of breast
0.908 0.092 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.905 0.094 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.905 0.095 0.000
M81 Osteoporosis without pathological fracture
0.904 0.096 0.000
M24 Other specific joint derangements
0.900 0.100 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.897 0.103 0.000
Z45.2 Adjustment and management of vascular access device
0.896 0.104 0.000
C78.0 Secondary malignant neoplasm of lung
0.895 0.105 0.000
Y85 Sequelae of transport accidents
0.893 0.107 0.000
Z63 Other problems related to primary support group, including family circumstances
0.892 0.108 0.000
S52 Fracture of forearm
0.891 0.109 0.000
C78.7 Secondary malignant neoplasm of liver
0.883 0.117 0.000
Z43 Attention to artificial openings
0.883 0.117 0.000
D75 Other diseases of blood and blood-forming organs
0.882 0.118 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.882 0.118 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.881 0.119 0.000
Z45.8 Adjustment and management of other implanted devices
0.878 0.122 0.000
Y40 Systemic antibiotics
0.877 0.123 0.000
M06.0 Seronegative rheumatoid arthritis
0.875 0.125 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
M81.9 Osteoporosis, unspecified
0.873 0.127 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.871 0.129 0.000
S92 Fracture of foot, except ankle
0.871 0.129 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.869 0.131 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.869 0.131 0.000
S40-S49 Injuries to the shoulder and upper arm
0.863 0.137 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.859 0.141 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.858 0.142 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.857 0.143 0.000
T81 Complications of procedures, not elsewhere classified
0.856 0.144 0.000
M23 Internal derangement of knee
0.855 0.145 0.000
M89.8 Other specified disorders of bone
0.854 0.146 0.000
M90.7 Fracture of bone in neoplastic disease
0.853 0.147 0.000
D86 Sarcoidosis
0.852 0.148 0.000
Y86 Sequelae of other accidents
0.851 0.149 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.850 0.150 0.000
D00-D09 In situ neoplasms
0.848 0.152 0.000
M89.9 Disorder of bone, unspecified
0.848 0.152 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.847 0.153 0.000
D68.2 Hereditary deficiency of other clotting factors
0.844 0.156 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.843 0.157 0.000
S91 Open wound of ankle and foot
0.842 0.157 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.841 0.159 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.839 0.161 0.000
C50.1 Central portion of breast
0.836 0.164 0.000
M86 Osteomyelitis
0.833 0.167 0.000
V40-V49 Car occupant injured in transport accident
0.833 0.167 0.000
L20-L30 Dermatitis and eczema
0.831 0.169 0.000
M24.1 Other articular cartilage disorders
0.829 0.171 0.000
X10-X19 Contact with heat and hot substances
0.828 0.172 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.824 0.176 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.824 0.176 0.000
T79-T79 Certain early complications of trauma
0.823 0.177 0.000
L98.0 Pyogenic granuloma
0.822 0.178 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.817 0.182 0.000
C50.3 Lower-inner quadrant of breast
0.816 0.184 0.000
D68.9 Coagulation defect, unspecified
0.815 0.185 0.000
D75.2 Essential thrombocytosis
0.814 0.186 0.000
M30 Polyarteritis nodosa and related conditions
0.812 0.188 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.811 0.189 0.000
Y40.9 Systemic antibiotic, unspecified
0.807 0.193 0.000
C50.5 Lower-outer quadrant of breast
0.807 0.193 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.805 0.195 0.000
Y60.0 During surgical operation
0.804 0.196 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.803 0.197 0.000
M10 Gout
0.802 0.198 0.000
M11 Other crystal arthropathies
0.796 0.204 0.000
Y95 Nosocomial condition
0.792 0.208 0.000
Z63.8 Other specified problems related to primary support group
0.787 0.213 0.000
M65-M68 Disorders of synovium and tendon
0.787 0.213 0.000
S92.3 Fracture of metatarsal bone
0.785 0.215 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.782 0.218 0.000
Z42 Follow-up care involving plastic surgery
0.777 0.223 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
M87 Osteonecrosis
0.776 0.224 0.000
M89.3 Hypertrophy of bone
0.775 0.225 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.775 0.225 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.774 0.226 0.000
Z63.5 Disruption of family by separation and divorce
0.773 0.227 0.000
S52.6 Fracture of lower end of both ulna and radius
0.773 0.227 0.000
M31 Other necrotising vasculopathies
0.772 0.228 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.771 0.229 0.000
D69.6 Thrombocytopenia, unspecified
0.771 0.229 0.000
D80 Immunodeficiency with predominantly antibody defects
0.770 0.230 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.769 0.231 0.000
M06.4 Inflammatory polyarthropathy
0.768 0.232 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.767 0.233 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.767 0.233 0.000
S20-S29 Injuries to the thorax
0.766 0.234 0.000
D83 Common variable immunodeficiency
0.766 0.234 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.763 0.237 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.762 0.238 0.000
T93 Sequelae of injuries of lower limb
0.758 0.242 0.000
Z43.3 Attention to colostomy
0.757 0.243 0.000
Z59 Problems related to housing and economic circumstances
0.757 0.243 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.755 0.245 0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.755 0.245 0.000
Y00-Y09 Assault
0.755 0.245 0.000
D86.9 Sarcoidosis, unspecified
0.754 0.246 0.000
C67.1 Dome of bladder
0.754 0.246 0.000
Z63.7 Other stressful life events affecting family and household
0.753 0.247 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.752 0.248 0.000
S90 Superficial injury of ankle and foot
0.752 0.248 0.000
L27 Dermatitis due to substances taken internally
0.750 0.250 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.750 0.250 0.000
M80 Osteoporosis with pathological fracture
0.749 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.748 0.251 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.748 0.252 0.000
Z29 Need for other prophylactic measures
0.748 0.252 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.748 0.252 0.000
Y40.8 Other systemic antibiotics
0.748 0.252 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.747 0.253 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.746 0.254 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.744 0.256 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.743 0.257 0.000
Z56 Problems related to employment and unemployment
0.742 0.257 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
D86.8 Sarcoidosis of other and combined sites
0.742 0.258 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.741 0.259 0.000
C79.2 Secondary malignant neoplasm of skin
0.740 0.260 0.000
S00-S09 Injuries to the head
0.740 0.260 0.000
L10-L14 Bullous disorders
0.740 0.260 0.000
S56 Injury of muscle and tendon at forearm level
0.738 0.262 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.736 0.264 0.000
M06.3 Rheumatoid nodule
0.735 0.265 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.735 0.265 0.000
S54 Injury of nerves at forearm level
0.733 0.267 0.000
S00 Superficial injury of head
0.733 0.267 0.000
C67.8 Overlapping lesion of bladder
0.733 0.267 0.000
M00-M03 Infectious arthropathies
0.733 0.267 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.731 0.269 0.000
Y43 Primarily systemic agents
0.731 0.269 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.731 0.269 0.000
Y85.0 Sequelae of motor-vehicle accident
0.731 0.269 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.731 0.269 0.000
V80-V89 Other land transport accidents
0.731 0.269 0.000
S52.1 Fracture of upper end of radius
0.730 0.270 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.730 0.270 0.000
D09 Carcinoma in situ of other and unspecified sites
0.730 0.270 0.000
S91.3 Open wound of other parts of foot
0.729 0.271 0.000
M14 Arthropathies in other diseases classified elsewhere
0.729 0.271 0.000
Z43.1 Attention to gastrostomy
0.729 0.271 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.728 0.271 0.000
D68.5 Primary Thrombophilia
0.728 0.272 0.000
C50.0 Nipple and areola
0.728 0.272 0.000
D55-D59 Haemolytic anaemias
0.727 0.273 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.726 0.273 0.000
S52.7 Multiple fractures of forearm
0.726 0.274 0.000
T00-T07 Injuries involving multiple body regions
0.726 0.274 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.726 0.274 0.000
M89.5 Osteolysis
0.725 0.274 0.000
V10-V19 Pedal cyclist injured in transport accident
0.724 0.276 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.724 0.276 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.724 0.276 0.000
S92.30 Fracture of metatarsal bone (closed)
0.724 0.276 0.000
S70-S79 Injuries to the hip and thigh
0.723 0.277 0.000
C67.3 Anterior wall of bladder
0.723 0.277 0.000
T66-T78 Other and unspecified effects of external causes
0.722 0.278 0.000
Z63.4 Disappearance and death of family member
0.721 0.279 0.000
S50 Superficial injury of forearm
0.721 0.279 0.000
Z44 Fitting and adjustment of external prosthetic device
0.720 0.280 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.719 0.281 0.000
M86.9 Osteomyelitis, unspecified
0.718 0.282 0.000
L93 Lupus erythematosus
0.718 0.282 0.000
Z51.9 Medical care, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
Chapter I Certain infectious and parasitic diseases
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.716 0.284 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.715 0.285 0.000
C67.4 Posterior wall of bladder
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.285 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.714 0.286 0.000
S00.1 Contusion of eyelid and periocular area
0.713 0.287 0.000
M23.9 Internal derangement of knee, unspecified
0.712 0.288 0.000
Z45.3 Adjustment and management of implanted hearing device
0.712 0.288 0.000
M82 Osteoporosis in diseases classified elsewhere
0.710 0.290 0.000
S31 Open wound of abdomen, lower back and pelvis
0.710 0.290 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.710 0.290 0.000
S92.4 Fracture of great toe
0.708 0.292 0.000
M89.83 Other specified disorders of bone (Forearm)
0.708 0.292 0.000
M40-M43 Deforming dorsopathies
0.707 0.293 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.707 0.293 0.000
M84 Disorders of continuity of bone
0.706 0.294 0.000
M24.7 Protrusio acetabuli
0.706 0.294 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.705 0.295 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.704 0.296 0.000
Y40.3 Macrolides
0.704 0.296 0.000
C65 Malignant neoplasm of renal pelvis
0.703 0.297 0.000
C50.6 Axillary tail of breast
0.702 0.298 0.000
D67 Hereditary factor IX deficiency
0.702 0.298 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
S52.2 Fracture of shaft of ulna
0.702 0.298 0.000
M34 Systemic sclerosis
0.701 0.299 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.700 0.300 0.000
L83 Acanthosis nigricans
0.700 0.300 0.000
Z52 Donors of organs and tissues
0.700 0.300 0.000
S52.3 Fracture of shaft of radius
0.699 0.300 0.000
D45 Polycythaemia vera
0.699 0.301 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.697 0.303 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.697 0.303 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
T86 Failure and rejection of transplanted organs and tissues
0.695 0.305 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.693 0.307 0.000
L87 Transepidermal elimination disorders
0.693 0.307 0.000
L88 Pyoderma gangrenosum
0.693 0.307 0.000
L86 Keratoderma in diseases classified elsewhere
0.693 0.307 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.693 0.307 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.693 0.307 0.000
L98.5 Mucinosis of skin
0.693 0.307 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.693 0.307 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.693 0.307 0.000
L98.1 Factitial dermatitis
0.693 0.307 0.000
D69.5 Secondary thrombocytopenia
0.693 0.307 0.000
S51 Open wound of forearm
0.693 0.307 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.692 0.308 0.000
S98 Traumatic amputation of ankle and foot
0.692 0.308 0.000
S97 Crushing injury of ankle and foot
0.692 0.308 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.692 0.308 0.000
S95 Injury of blood vessels at ankle and foot level
0.692 0.308 0.000
S94 Injury of nerves at ankle and foot level
0.692 0.308 0.000
M89.0 Algoneurodystrophy
0.692 0.308 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.308 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.691 0.309 0.000
M88 Paget's disease of bone [osteitis deformans]
0.691 0.309 0.000
M31.6 Other giant cell arteritis
0.691 0.309 0.000
C79.6 Secondary malignant neoplasm of ovary
0.690 0.310 0.000
Z22 Carrier of infectious disease
0.689 0.311 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.688 0.312 0.000
Y89 Sequelae of other external causes
0.688 0.312 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.688 0.312 0.000
Z43.0 Attention to tracheostomy
0.688 0.312 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.688 0.312 0.000
M89.6 Osteopathy after poliomyelitis
0.688 0.312 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.688 0.312 0.000
M89.2 Other disorders of bone development and growth
0.688 0.312 0.000
M89.1 Epiphyseal arrest
0.688 0.312 0.000
D74 Methaemoglobinaemia
0.687 0.313 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.687 0.313 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.687 0.313 0.000
S41 Open wound of shoulder and upper arm
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.313 0.000
D69.4 Other primary thrombocytopenia
0.687 0.313 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.686 0.314 0.000
L94 Other localised connective tissue disorders
0.686 0.314 0.000
Z51.6 Desensitisation to allergens
0.686 0.314 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.685 0.315 0.000
S59 Other and unspecified injuries of forearm
0.685 0.315 0.000
S58 Traumatic amputation of forearm
0.685 0.315 0.000
S57 Crushing injury of forearm
0.685 0.315 0.000
S55 Injury of blood vessels at forearm level
0.685 0.315 0.000
M83 Adult osteomalacia
0.684 0.316 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
S10-S19 Injuries to the neck
0.682 0.318 0.000
Y88 Sequelae of surgical and medical care as external cause
0.682 0.318 0.000
X12 Contact with other hot fluids
0.682 0.318 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.681 0.319 0.000
M33 Dermatopolymyositis
0.681 0.319 0.000
M32 Systemic lupus erythematosus
0.681 0.319 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.681 0.319 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.681 0.319 0.000
Chapter VI Diseases of the nervous system
0.680 0.320 0.000
Z64 Problems related to certain psychosocial circumstances
0.680 0.320 0.000
M24.5 Contracture of joint
0.678 0.322 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.678 0.322 0.000
T92 Sequelae of injuries of upper limb
0.678 0.322 0.000
M60-M63 Disorders of muscles
0.677 0.322 0.000
D66 Hereditary factor VIII deficiency
0.677 0.323 0.000
M81.2 Osteoporosis of disuse
0.677 0.323 0.000
S52.4 Fracture of shafts of both ulna and radius
0.677 0.323 0.000
S99 Other and unspecified injuries of ankle and foot
0.677 0.323 0.000
M23.3 Other meniscus derangements
0.676 0.324 0.000
T93.2 Sequelae of other fractures of lower limb
0.674 0.326 0.000
M24.6 Ankylosis of joint
0.674 0.326 0.000
S91.0 Open wound of ankle
0.674 0.326 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.674 0.326 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.674 0.326 0.000
D84 Other immunodeficiencies
0.674 0.326 0.000
D82 Immunodeficiency associated with other major defects
0.674 0.326 0.000
D81 Combined immunodeficiencies
0.674 0.326 0.000
S37 Injury of urinary and pelvic organs
0.673 0.327 0.000
T18 Foreign body in alimentary tract
0.673 0.327 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.673 0.327 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.672 0.328 0.000
M85 Other disorders of bone density and structure
0.672 0.328 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.672 0.328 0.000
S36 Injury of intra-abdominal organs
0.671 0.329 0.000
S00.0 Superficial injury of scalp
0.671 0.329 0.000
C67.7 Urachus
0.670 0.330 0.000
C67.0 Trigone of bladder
0.670 0.330 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.669 0.331 0.000
T87 Complications peculiar to reattachment and amputation
0.668 0.332 0.000
D06 Carcinoma in situ of cervix uteri
0.668 0.332 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.667 0.333 0.000
D68.4 Acquired coagulation factor deficiency
0.666 0.334 0.000
D68.1 Hereditary factor XI deficiency
0.666 0.334 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.666 0.334 0.000
M91-M94 Chondropathies
0.666 0.334 0.000
L50-L54 Urticaria and erythema
0.666 0.334 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.664 0.336 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
M30.0 Polyarteritis nodosa
0.664 0.336 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.662 0.337 0.000
C49.0 Connective and soft tissue of head, face and neck
0.662 0.338 0.000
S92.5 Fracture of other toe
0.662 0.338 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.662 0.338 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.661 0.339 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.659 0.341 0.000
Z65 Problems related to other psychosocial circumstances
0.659 0.341 0.000
Z62 Other problems related to upbringing
0.659 0.341 0.000
Z61 Problems related to negative life events in childhood
0.659 0.341 0.000
Z58 Problems related to physical environment
0.659 0.341 0.000
Z55 Problems related to education and literacy
0.659 0.341 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.659 0.341 0.000
Y58 Bacterial vaccines
0.659 0.341 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.659 0.341 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.659 0.341 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.658 0.342 0.000
M25 Other joint disorders, not elsewhere classified
0.658 0.342 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.658 0.342 0.000
C66 Malignant neoplasm of ureter
0.657 0.343 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.656 0.344 0.000
Y52 Agents primarily affecting the cardiovascular system
0.655 0.344 0.000
D69.8 Other specified haemorrhagic conditions
0.655 0.344 0.000
D69.2 Other nonthrombocytopenic purpura
0.655 0.344 0.000
D69.1 Qualitative platelet defects
0.655 0.344 0.000
D69.0 Allergic purpura
0.655 0.344 0.000
M23.8 Other internal derangements of knee
0.655 0.345 0.000
D68.6 Other Thrombophilia
0.655 0.345 0.000
M23.5 Chronic instability of knee
0.654 0.345 0.000
T17 Foreign body in respiratory tract
0.654 0.346 0.000
Z45.1 Adjustment and management of infusion pump
0.654 0.346 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.654 0.346 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.653 0.346 0.000
M90.6 Osteitis deformans in neoplastic disease
0.653 0.346 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.653 0.346 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.653 0.346 0.000
M90.3 Osteonecrosis in caisson disease
0.653 0.346 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.653 0.346 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.653 0.346 0.000
M90.0 Tuberculosis of bone
0.653 0.346 0.000
A80-A89 Viral infections of the central nervous system
0.654 0.346 0.000
M05.8 Other seropositive rheumatoid arthritis
0.653 0.347 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.653 0.347 0.000
M05.2 Rheumatoid vasculitis
0.653 0.347 0.000
M05.1 Rheumatoid lung disease
0.653 0.347 0.000
M05.0 Felty's syndrome
0.653 0.347 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.652 0.348 0.000
V20-V29 Motorcycle rider injured in transport accident
0.652 0.348 0.000
Y48 Anaesthetics and therapeutic gases
0.652 0.348 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.652 0.348 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.652 0.348 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.651 0.349 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.651 0.349 0.000
M11.2 Other chondrocalcinosis
0.651 0.349 0.000
M89.98 Disorder of bone, unspecified (Other)
0.651 0.349 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.650 0.350 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.650 0.350 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.649 0.351 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.649 0.351 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.649 0.351 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.649 0.351 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.649 0.351 0.000
Y64 Contaminated medical or biological substances
0.649 0.351 0.000
Y63 Failure in dosage during surgical and medical care
0.649 0.351 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.649 0.351 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.649 0.351 0.000
Y69 Unspecified misadventure during surgical and medical care
0.649 0.351 0.000
Y66 Nonadministration of surgical and medical care
0.649 0.351 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.649 0.351 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.649 0.351 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.648 0.352 0.000
L80 Vitiligo
0.648 0.352 0.000
M81.8 Other osteoporosis
0.648 0.352 0.000
M81.6 Localised osteoporosis [Lequesne]
0.648 0.352 0.000
M81.5 Idiopathic osteoporosis
0.648 0.352 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.648 0.352 0.000
M81.1 Postoophorectomy osteoporosis
0.648 0.352 0.000
M81.0 Postmenopausal osteoporosis
0.648 0.352 0.000
D69.9 Haemorrhagic condition, unspecified
0.647 0.353 0.000
Y43.3 Other antineoplastic drugs
0.647 0.353 0.000
M24.9 Joint derangement, unspecified
0.646 0.354 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.646 0.354 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.645 0.354 0.000
Z29.8 Other specified prophylactic measures
0.645 0.355 0.000
D09.0 Bladder
0.645 0.355 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.645 0.355 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.643 0.357 0.000
M23.0 Cystic meniscus
0.642 0.358 0.000
S29 Other and unspecified injuries of thorax
0.642 0.358 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.642 0.358 0.000
D83.9 Common variable immunodeficiency, unspecified
0.641 0.359 0.000
D68.8 Other specified coagulation defects
0.640 0.360 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.640 0.360 0.000
Z54 Convalescence
0.640 0.360 0.000
Z63.9 Problem related to primary support group, unspecified
0.639 0.361 0.000
Z63.6 Dependent relative needing care at home
0.639 0.361 0.000
Z63.3 Absence of family member
0.639 0.361 0.000
Z63.2 Inadequate family support
0.639 0.361 0.000
Z63.1 Problems in relationship with parents and in-laws
0.639 0.361 0.000
Y45.0 Opioids and related analgesics
0.639 0.361 0.000
S93.1 Dislocation of toe(s)
0.639 0.361 0.000
S52.9 Fracture of forearm, part unspecified
0.638 0.361 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.638 0.362 0.000
D02.0 Larynx
0.638 0.362 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.637 0.363 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.635 0.364 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.635 0.365 0.000
M21.3 Wrist or foot drop (acquired)
0.633 0.367 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.633 0.367 0.000
Z43.9 Attention to unspecified artificial opening
0.633 0.367 0.000
Z43.7 Attention to artificial vagina
0.633 0.367 0.000
D75.0 Familial erythrocytosis
0.632 0.368 0.000
C49.9 Connective and soft tissue, unspecified
0.632 0.368 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.632 0.368 0.000
T95 Sequelae of burns, corrosions and frostbite
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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