TreeWAS – Variant ID: rs76245856

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.001	0.999
Chapter II Neoplasms	0.999	0.001	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.991	0.008	0.000
I21 Acute myocardial infarction	0.000	0.012	0.988
I20.0 Unstable angina	0.000	0.013	0.987
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.986	0.014	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.985	0.015	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.984	0.016	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.017	0.983
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.978	0.022	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.971	0.029	0.000
Z87 Personal history of other diseases and conditions	0.970	0.030	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.969	0.031	0.000
C60-C63 Malignant neoplasms of male genital organs	0.966	0.034	0.000
Chapter V Mental and behavioural disorders	0.965	0.035	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.964	0.036	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.963	0.037	0.000
Z30 Contraceptive management	0.959	0.041	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.045	0.955
Chapter XV Pregnancy, childbirth and the puerperium	0.951	0.049	0.000
Chapter I Certain infectious and parasitic diseases	0.948	0.052	0.000
C79 Secondary malignant neoplasm of other sites	0.943	0.057	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.941	0.059	0.000
C61 Malignant neoplasm of prostate	0.939	0.061	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.938	0.062	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.933	0.067	0.000
Chapter XIV Diseases of the genitourinary system	0.932	0.068	0.000
Z30.2 Sterilisation	0.917	0.083	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.912	0.088	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.909	0.091	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.908	0.092	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.906	0.094	0.000
O60-O75 Complications of labour and delivery	0.906	0.094	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.906	0.094	0.000
Z93 Artificial opening status	0.903	0.097	0.000
C78.0 Secondary malignant neoplasm of lung	0.897	0.103	0.000
C64-C68 Malignant neoplasms of urinary tract	0.893	0.107	0.000
Z45 Adjustment and management of implanted device	0.892	0.108	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.892	0.108	0.000
C78.7 Secondary malignant neoplasm of liver	0.887	0.113	0.000
Z88.5 Personal history of allergy to narcotic agent	0.886	0.114	0.000
B95-B98 Bacterial, viral and other infectious agents	0.882	0.118	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.879	0.121	0.000
Z87.1 Personal history of diseases of the digestive system	0.876	0.124	0.000
Z53.0 Procedure not carried out because of contraindication	0.870	0.130	0.000
Z13 Special screening examination for other diseases and disorders	0.866	0.134	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.135	0.865
Z53.8 Procedure not carried out for other reasons	0.859	0.141	0.000
Z90.2 Acquired absence of lung [part of]	0.856	0.144	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.853	0.147	0.000
Z34 Supervision of normal pregnancy	0.853	0.147	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.849	0.151	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.849	0.151	0.000
Chapter X Diseases of the respiratory system	0.849	0.151	0.000
F41 Other anxiety disorders	0.846	0.154	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.840	0.160	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.840	0.160	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.838	0.162	0.000
Z90.7 Acquired absence of genital organ(s)	0.837	0.163	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.836	0.164	0.000
Z49 Care involving dialysis	0.835	0.165	0.000
Z90.1 Acquired absence of breast(s)	0.833	0.167	0.000
S80-S89 Injuries to the knee and lower leg	0.832	0.168	0.000
Z46 Fitting and adjustment of other devices	0.831	0.169	0.000
C67 Malignant neoplasm of bladder	0.820	0.180	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.819	0.181	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.816	0.184	0.000
F30-F39 Mood [affective] disorders	0.813	0.187	0.000
S50-S59 Injuries to the elbow and forearm	0.811	0.189	0.000
E00-E07 Disorders of thyroid gland	0.809	0.191	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.807	0.193	0.000
Z42 Follow-up care involving plastic surgery	0.807	0.193	0.000
N17-N19 Renal failure	0.807	0.193	0.000
N40-N51 Diseases of male genital organs	0.805	0.195	0.000
Z45.8 Adjustment and management of other implanted devices	0.801	0.199	0.000
N00-N08 Glomerular diseases	0.794	0.206	0.000
C73 Malignant neoplasm of thyroid gland	0.793	0.207	0.000
F41.9 Anxiety disorder, unspecified	0.792	0.208	0.000
Z94 Transplanted organ and tissue status	0.791	0.208	0.000
Z48 Other surgical follow-up care	0.791	0.209	0.000
Z39 Postpartum care and examination	0.790	0.210	0.000
S40-S49 Injuries to the shoulder and upper arm	0.786	0.214	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.786	0.214	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.785	0.215	0.000
J30-J39 Other diseases of upper respiratory tract	0.780	0.220	0.000
D00-D09 In situ neoplasms	0.778	0.222	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.223	0.777
O75 Other complications of labour and delivery, not elsewhere classified	0.774	0.226	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.769	0.231	0.000
A00-A09 Intestinal infectious diseases	0.766	0.234	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.765	0.235	0.000
Z93.3 Colostomy status	0.765	0.235	0.000
Z33 Pregnant state, incidental	0.762	0.238	0.000
Z45.2 Adjustment and management of vascular access device	0.761	0.239	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.761	0.239	0.000
Z13.9 Special screening examination, unspecified	0.761	0.239	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.239	0.761
Z93.2 Ileostomy status	0.760	0.240	0.000
Z40 Prophylactic surgery	0.760	0.240	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.241	0.000
Z85 Personal history of malignant neoplasm	0.758	0.242	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.758	0.242	0.000
C78.2 Secondary malignant neoplasm of pleura	0.757	0.243	0.000
N48 Other disorders of penis	0.750	0.250	0.000
S00-S09 Injuries to the head	0.746	0.253	0.000
E50-E64 Other nutritional deficiencies	0.745	0.255	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.744	0.256	0.000
Z87.0 Personal history of diseases of the respiratory system	0.741	0.259	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.741	0.259	0.000
N30-N39 Other diseases of urinary system	0.740	0.260	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.738	0.262	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.738	0.262	0.000
O63 Long labour	0.737	0.263	0.000
Chapter VII Diseases of the eye and adnexa	0.736	0.264	0.000
Chapter XXII Codes for special purposes	0.736	0.264	0.000
T66-T78 Other and unspecified effects of external causes	0.736	0.264	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.736	0.264	0.000
Z36 Antenatal screening	0.735	0.265	0.000
Z34.8 Supervision of other normal pregnancy	0.734	0.266	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.733	0.267	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.733	0.267	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.732	0.268	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.732	0.268	0.000
S20-S29 Injuries to the thorax	0.729	0.271	0.000
R47-R49 Symptoms and signs involving speech and voice	0.728	0.272	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.726	0.274	0.000
C34 Malignant neoplasm of bronchus and lung	0.726	0.274	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.725	0.275	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.725	0.275	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.724	0.276	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.723	0.277	0.000
O70 Perineal laceration during delivery	0.722	0.278	0.000
Z46.6 Fitting and adjustment of urinary device	0.721	0.279	0.000
A80-A89 Viral infections of the central nervous system	0.720	0.280	0.000
C62 Malignant neoplasm of testis	0.719	0.281	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.719	0.281	0.000
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.5 Ischaemic cardiomyopathy	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
I22 Subsequent myocardial infarction	0.000	0.283	0.717
C79.9 Secondary malignant neoplasm, unspecified site	0.716	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.283	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.283	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.283	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.283	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.715	0.285	0.000
I25.2 Old myocardial infarction	0.000	0.286	0.714
Z43 Attention to artificial openings	0.714	0.286	0.000
Chapter VI Diseases of the nervous system	0.714	0.286	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.714	0.286	0.000
E03 Other hypothyroidism	0.714	0.286	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.712	0.288	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.711	0.289	0.000
Z89 Acquired absence of limb	0.711	0.289	0.000
Z84 Family history of other conditions	0.711	0.289	0.000
Z81 Family history of mental and behavioural disorders	0.711	0.289	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.292	0.708
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.292	0.708
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.292	0.708
O34 Maternal care for known or suspected abnormality of pelvic organs	0.708	0.292	0.000
C80 Malignant neoplasm without specification of site	0.707	0.293	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.707	0.293	0.000
Z54 Convalescence	0.706	0.294	0.000
Z52 Donors of organs and tissues	0.706	0.294	0.000
Z44 Fitting and adjustment of external prosthetic device	0.706	0.294	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.706	0.294	0.000
Z38 Liveborn infants according to place of birth	0.706	0.294	0.000
Z32 Pregnancy examination and test	0.706	0.294	0.000
Z31 Procreative management	0.706	0.294	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.705	0.295	0.000
I20.8 Other forms of angina pectoris	0.000	0.298	0.701
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.701	0.299	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.701	0.299	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.701	0.299	0.000
C67.9 Bladder, unspecified	0.701	0.299	0.000
F41.2 Mixed anxiety and depressive disorder	0.701	0.299	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.698	0.302	0.000
Z49.1 Extracorporeal dialysis	0.698	0.302	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.698	0.302	0.000
F43 Reaction to severe stress, and adjustment disorders	0.697	0.303	0.000
S52 Fracture of forearm	0.697	0.303	0.000
Z99.3 Dependence on wheelchair	0.697	0.303	0.000
Z90.8 Acquired absence of other organs	0.696	0.304	0.000
Z90.3 Acquired absence of part of stomach	0.696	0.304	0.000
Z90.0 Acquired absence of part of head and neck	0.696	0.304	0.000
Z87.8 Personal history of other specified conditions	0.696	0.304	0.000
Z87.6 Personal history of certain conditions arising in the perinatal period	0.696	0.304	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.696	0.304	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.695	0.305	0.000
T79-T79 Certain early complications of trauma	0.695	0.305	0.000
T33-T35 Frostbite	0.695	0.305	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.695	0.305	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.695	0.305	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.695	0.305	0.000
T00-T07 Injuries involving multiple body regions	0.695	0.305	0.000
S90-S99 Injuries to the ankle and foot	0.695	0.305	0.000
S10-S19 Injuries to the neck	0.695	0.305	0.000
O73 Retained placenta and membranes, without haemorrhage	0.694	0.306	0.000
N03 Chronic nephritic syndrome	0.694	0.306	0.000
F40 Phobic anxiety disorders	0.694	0.306	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.693	0.306	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.693	0.307	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.692	0.307	0.000
C60 Malignant neoplasm of penis	0.692	0.307	0.000
E04 Other non-toxic goitre	0.692	0.308	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.692	0.308	0.000
F99-F99 Unspecified mental disorder	0.692	0.308	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.692	0.308	0.000
F80-F89 Disorders of psychological development	0.692	0.308	0.000
F70-F79 Mental retardation	0.692	0.308	0.000
F60-F69 Disorders of adult personality and behaviour	0.692	0.308	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.692	0.308	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.691	0.308	0.000
Z10 Routine general health check-up of defined subpopulation	0.691	0.308	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.690	0.310	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.690	0.310	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.690	0.310	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.690	0.310	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.690	0.310	0.000
N48.6 Balanitis xerotica obliterans	0.690	0.310	0.000
A30-A49 Other bacterial diseases	0.690	0.310	0.000
N99-N99 Other disorders of the genitourinary system	0.689	0.311	0.000
Z30.9 Contraceptive management, unspecified	0.688	0.312	0.000
Z30.8 Other contraceptive management	0.688	0.312	0.000
Z30.4 Surveillance of contraceptive drugs	0.688	0.312	0.000
Z30.3 Menstrual extraction	0.688	0.312	0.000
Z30.0 General counselling and advice on contraception	0.688	0.312	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.687	0.313	0.000
E70-E90 Metabolic disorders	0.686	0.313	0.000
N60-N64 Disorders of breast	0.686	0.314	0.000
R06 Abnormalities of breathing	0.685	0.315	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.684	0.316	0.000
F33 Recurrent depressive disorder	0.683	0.317	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.683	0.317	0.000
O85-O92 Complications predominantly related to the puerperium	0.682	0.318	0.000
D46 Myelodysplastic syndromes	0.682	0.318	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.681	0.318	0.000
Z02 Examination and encounter for administrative purposes	0.680	0.320	0.000
B99-B99 Other infectious diseases	0.680	0.320	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.680	0.320	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320	0.000
B65-B83 Helminthiases	0.680	0.320	0.000
B50-B64 Protozoal diseases	0.680	0.320	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.680	0.320	0.000
B15-B19 Viral hepatitis	0.680	0.320	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.680	0.320	0.000
A75-A79 Rickettsioses	0.680	0.320	0.000
A70-A74 Other diseases caused by chlamydiae	0.680	0.320	0.000
A65-A69 Other spirochaetal diseases	0.680	0.320	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.680	0.320	0.000
A20-A28 Certain zoonotic bacterial diseases	0.680	0.320	0.000
A15-A19 Tuberculosis	0.680	0.320	0.000
Z90.5 Acquired absence of kidney	0.680	0.320	0.000
Z35 Supervision of high-risk pregnancy	0.678	0.322	0.000
N10-N16 Renal tubulo-interstitial diseases	0.678	0.322	0.000
Z93.6 Other artificial openings of urinary tract status	0.678	0.322	0.000
J09-J18 Influenza and pneumonia	0.677	0.323	0.000
N20-N23 Urolithiasis	0.677	0.323	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.677	0.323	0.000
Z04 Examination and observation for other reasons	0.676	0.324	0.000
C79.6 Secondary malignant neoplasm of ovary	0.676	0.324	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.676	0.324	0.000
C79.2 Secondary malignant neoplasm of skin	0.676	0.324	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.676	0.324	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.676	0.324	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.676	0.324	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.675	0.324	0.000
Z53.9 Procedure not carried out, unspecified reason	0.675	0.325	0.000
J34 Other disorders of nose and nasal sinuses	0.675	0.325	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.675	0.325	0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.674	0.326	0.000
O72 Postpartum haemorrhage	0.674	0.326	0.000
F03 Unspecified dementia	0.673	0.327	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.672	0.328	0.000
C67.5 Bladder neck	0.672	0.328	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.672	0.328	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.672	0.328	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.671	0.329	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.671	0.329	0.000
N18 Chronic renal failure	0.671	0.329	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.670	0.330	0.000
S82 Fracture of lower leg, including ankle	0.670	0.330	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.667	0.333	0.000
B25-B34 Other viral diseases	0.667	0.333	0.000
Z97 Presence of other devices	0.665	0.335	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.665	0.335	0.000
J60-J70 Lung diseases due to external agents	0.663	0.337	0.000
Z93.1 Gastrostomy status	0.663	0.337	0.000
Z34.0 Supervision of normal first pregnancy	0.662	0.338	0.000
Chapter XX External causes of morbidity and mortality	0.662	0.338	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.662	0.338	0.000
Z50 Care involving use of rehabilitation procedures	0.662	0.338	0.000
C67.2 Lateral wall of bladder	0.659	0.340	0.000
B35-B49 Mycoses	0.659	0.341	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.658	0.342	0.000
N32 Other disorders of bladder	0.656	0.344	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.655	0.345	0.000
O36 Maternal care for other known or suspected foetal problems	0.654	0.346	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.652	0.347	0.000
H40-H42 Glaucoma	0.652	0.348	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.651	0.349	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.651	0.349	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.651	0.349	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.651	0.349	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.651	0.349	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.651	0.349	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.651	0.349	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.651	0.349	0.000
D45 Polycythaemia vera	0.651	0.349	0.000
R06.5 Mouth breathing	0.651	0.349	0.000
I24 Other acute ischaemic heart diseases	0.000	0.349	0.650
Z49.0 Preparatory care for dialysis	0.650	0.350	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.650	0.350	0.000
N30 Cystitis	0.650	0.350	0.000
R49 Voice disturbances	0.650	0.350	0.000
F48 Other neurotic disorders	0.650	0.350	0.000
F44 Dissociative [conversion] disorders	0.650	0.350	0.000
F42 Obsessive-compulsive disorder	0.650	0.350	0.000
O74 Complications of anaesthesia during labour and delivery	0.649	0.351	0.000
O71 Other obstetric trauma	0.649	0.351	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.649	0.351	0.000
O66 Other obstructed labour	0.649	0.351	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.649	0.351	0.000
O62 Abnormalities of forces of labour	0.649	0.351	0.000
O61 Failed induction of labour	0.649	0.351	0.000
O60 Preterm delivery	0.649	0.351	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.649	0.351	0.000
O70.1 Second degree perineal laceration during delivery	0.648	0.352	0.000
O00-O08 Pregnancy with abortive outcome	0.648	0.352	0.000
Z93.9 Artificial opening status, unspecified	0.647	0.353	0.000
Z93.8 Other artificial opening status	0.647	0.353	0.000
Z93.5 Cystostomy status	0.647	0.353	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.647	0.353	0.000
Z93.0 Tracheostomy status	0.647	0.353	0.000
E03.9 Hypothyroidism, unspecified	0.646	0.354	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.642	0.358	0.000
Z41 Procedures for purposes other than remedying health state	0.641	0.359	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.641	0.359	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.640	0.360	0.000
C66 Malignant neoplasm of ureter	0.640	0.360	0.000
C65 Malignant neoplasm of renal pelvis	0.640	0.360	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.640	0.360	0.000
Z45.3 Adjustment and management of implanted hearing device	0.640	0.360	0.000
Z45.1 Adjustment and management of infusion pump	0.640	0.360	0.000
E40-E46 Malnutrition	0.639	0.361	0.000
F45 Somatoform disorders	0.638	0.362	0.000
J00-J06 Acute upper respiratory infections	0.637	0.363	0.000
O46.9 Antepartum haemorrhage, unspecified	0.636	0.364	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.635	0.365	0.000
Z48.8 Other specified surgical follow-up care	0.633	0.367	0.000
J30 Vasomotor and allergic rhinitis	0.632	0.368	0.000
O42 Premature rupture of membranes	0.632	0.368	0.000
Chapter VIII Diseases of the ear and mastoid process	0.631	0.369	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.630	0.370	0.000
C74 Malignant neoplasm of adrenal gland	0.630	0.370	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.630	0.370	0.000
J35 Chronic diseases of tonsils and adenoids	0.629	0.371	0.000
N17 Acute renal failure	0.628	0.372	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.627	0.373	0.000
C50-C50 Malignant neoplasm of breast	0.627	0.373	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.627	0.373	0.000
Z94.0 Kidney transplant status	0.626	0.374	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.626	0.374	0.000
N25-N29 Other disorders of kidney and ureter	0.625	0.374	0.000
Z99.2 Dependence on renal dialysis	0.625	0.375	0.000
T92 Sequelae of injuries of upper limb	0.625	0.375	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.624	0.376	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.624	0.376	0.000
N03.9 Unspecified	0.623	0.377	0.000
S80 Superficial injury of lower leg	0.622	0.378	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.622	0.378	0.000
S70-S79 Injuries to the hip and thigh	0.622	0.378	0.000
E10-E14 Diabetes mellitus	0.622	0.378	0.000
R23 Other skin changes	0.622	0.378	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.621	0.379	0.000
D37.0 Lip, oral cavity and pharynx	0.621	0.379	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.620	0.379	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.620	0.379	0.000
Z13.5 Special screening examination for eye and ear disorders	0.620	0.379	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.620	0.379	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.620	0.379	0.000
Z13.2 Special screening examination for nutritional disorders	0.620	0.379	0.000
Z13.1 Special screening examination for diabetes mellitus	0.620	0.379	0.000
Z83 Family history of other specific disorders	0.620	0.379	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.620	0.380	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.619	0.380	0.000
Z39.1 Care and examination of lactating mother	0.618	0.382	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.618	0.382	0.000
E61 Deficiency of other nutrient elements	0.618	0.382	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.614	0.386	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.614	0.386	0.000
N19 Unspecified renal failure	0.613	0.387	0.000
J39 Other diseases of upper respiratory tract	0.613	0.387	0.000
E20-E35 Disorders of other endocrine glands	0.613	0.387	0.000
Z98 Other postsurgical states	0.612	0.388	0.000
F31 Bipolar affective disorder	0.612	0.388	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.611	0.388	0.000
Z39.0 Care and examination immediately after delivery	0.611	0.389	0.000
S01 Open wound of head	0.610	0.390	0.000
O45 Premature separation of placenta [abruptio placentae]	0.609	0.391	0.000
O44 Placenta praevia	0.609	0.391	0.000
O43 Placental disorders	0.609	0.391	0.000
O41 Other disorders of amniotic fluid and membranes	0.609	0.391	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.609	0.391	0.000
O33 Maternal care for known or suspected disproportion	0.609	0.391	0.000
O31 Complications specific to multiple gestation	0.609	0.391	0.000
O30 Multiple gestation	0.609	0.391	0.000
O40 Polyhydramnios	0.609	0.391	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.609	0.391	0.000
S52.5 Fracture of lower end of radius	0.608	0.392	0.000
T14 Injury of unspecified body region	0.607	0.393	0.000
F41.8 Other specified anxiety disorders	0.607	0.393	0.000
F41.3 Other mixed anxiety disorders	0.607	0.393	0.000
F41.1 Generalised anxiety disorder	0.607	0.393	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.606	0.394	0.000
T17 Foreign body in respiratory tract	0.606	0.394	0.000
R05 Cough	0.605	0.395	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.604	0.396	0.000
S40 Superficial injury of shoulder and upper arm	0.603	0.396	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.604	0.396	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.602	0.398	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.602	0.398	0.000
C32 Malignant neoplasm of larynx	0.602	0.398	0.000
C31 Malignant neoplasm of accessory sinuses	0.602	0.398	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.602	0.398	0.000
C37 Malignant neoplasm of thymus	0.602	0.398	0.000
C33 Malignant neoplasm of trachea	0.602	0.398	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.602	0.398	0.000
J33 Nasal polyp	0.601	0.399	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.601	0.399	0.000
F02 Dementia in other diseases classified elsewhere	0.601	0.399	0.000
F01 Vascular dementia	0.601	0.399	0.000
F00 Dementia in Alzheimer's disease	0.601	0.399	0.000
F09 Unspecified organic or symptomatic mental disorder	0.601	0.399	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.601	0.399	0.000
N73 Other female pelvic inflammatory diseases	0.601	0.399	0.000
E86 Volume depletion	0.600	0.400	0.000
J34.2 Deviated nasal septum	0.599	0.401	0.000
Z49.2 Other dialysis	0.599	0.401	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.598	0.402	0.000
D37.4 Colon	0.598	0.402	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.598	0.402	0.000
Z94.8 Other transplanted organ and tissue status	0.598	0.402	0.000
S89 Other and unspecified injuries of lower leg	0.596	0.403	0.000
S88 Traumatic amputation of lower leg	0.596	0.403	0.000
S87 Crushing injury of lower leg	0.596	0.403	0.000
S86 Injury of muscle and tendon at lower leg level	0.596	0.403	0.000
S85 Injury of blood vessels at lower leg level	0.596	0.403	0.000
S84 Injury of nerves at lower leg level	0.596	0.403	0.000
S81 Open wound of lower leg	0.596	0.403	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.596	0.404	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.596	0.404	0.000
Z46.8 Fitting and adjustment of other specified devices	0.596	0.404	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.596	0.404	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.596	0.404	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.596	0.404	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.596	0.404	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.596	0.404	0.000
Z46.1 Fitting and adjustment of hearing aid	0.596	0.404	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.596	0.404	0.000
N48.4 Impotence of organic origin	0.595	0.405	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.595	0.405	0.000
R49.0 Dysphonia	0.594	0.406	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.593	0.407	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.593	0.407	0.000
Z48.9 Surgical follow-up care, unspecified	0.593	0.407	0.000
D41.4 Bladder	0.593	0.407	0.000
C34.9 Bronchus or lung, unspecified	0.592	0.408	0.000
M70-M79 Other soft tissue disorders	0.592	0.408	0.000
H40 Glaucoma	0.592	0.408	0.000
F32 Depressive episode	0.592	0.408	0.000
N40 Hyperplasia of prostate	0.591	0.409	0.000
D06 Carcinoma in situ of cervix uteri	0.591	0.409	0.000
A08 Viral and other specified intestinal infections	0.589	0.410	0.000
N32.9 Bladder disorder, unspecified	0.589	0.410	0.000
C67.8 Overlapping lesion of bladder	0.588	0.412	0.000
C67.7 Urachus	0.588	0.412	0.000
C67.6 Ureteric orifice	0.588	0.412	0.000
C67.4 Posterior wall of bladder	0.588	0.412	0.000
C67.3 Anterior wall of bladder	0.588	0.412	0.000
C67.1 Dome of bladder	0.588	0.412	0.000
C67.0 Trigone of bladder	0.588	0.412	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.587	0.412	0.000
Z99.8 Dependence on other enabling machines and devices	0.587	0.412	0.000
Z99.4 Dependence on artificial heart	0.587	0.412	0.000
Z99.0 Dependence on aspirator	0.587	0.412	0.000
O63.1 Prolonged second stage (of labour)	0.587	0.413	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations