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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76328823
log Bayes Factor = 13.0322
Chromosome 5   position 68,061,720  (GRCh37) Explore rs76328823 on Ensembl!
Variant rs76328823 is part of Cluster X0109

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Chapter II Neoplasms
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
C50-C50 Malignant neoplasm of breast
0.989 0.011 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.986 0.014 0.000
C50 Malignant neoplasm of breast
0.986 0.014 0.000
C15-C26 Malignant neoplasms of digestive organs
0.982 0.018 0.000
G40 Epilepsy
0.982 0.018 0.000
S06 Intracranial injury
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.976 0.024 0.000
N93 Other abnormal uterine and vaginal bleeding
0.974 0.026 0.000
N80 Endometriosis
0.974 0.026 0.000
S02 Fracture of skull and facial bones
0.973 0.027 0.000
S01 Open wound of head
0.971 0.029 0.000
O60-O75 Complications of labour and delivery
0.970 0.030 0.000
B95-B98 Bacterial, viral and other infectious agents
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.966 0.034 0.000
C50.9 Breast, unspecified
0.962 0.038 0.000
Chapter VII Diseases of the eye and adnexa
0.960 0.040 0.000
E70-E90 Metabolic disorders
0.960 0.040 0.000
M70-M79 Other soft tissue disorders
0.958 0.042 0.000
Chapter XXI Factors influencing health status and contact with health services
0.956 0.044 0.000
S00 Superficial injury of head
0.954 0.046 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.953 0.047 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.951 0.049 0.000
G47 Sleep disorders
0.946 0.054 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.945 0.055 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
Z48 Other surgical follow-up care
0.941 0.059 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.936 0.064 0.000
G40.9 Epilepsy, unspecified
0.934 0.066 0.000
B25-B34 Other viral diseases
0.931 0.069 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.929 0.071 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.917 0.083 0.000
H52 Disorders of refraction and accommodation
0.916 0.084 0.000
N30-N39 Other diseases of urinary system
0.913 0.087 0.000
T66-T78 Other and unspecified effects of external causes
0.911 0.089 0.000
Z48.8 Other specified surgical follow-up care
0.911 0.089 0.000
G90-G99 Other disorders of the nervous system
0.909 0.090 0.000
C18 Malignant neoplasm of colon
0.909 0.091 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.908 0.092 0.000
E10-E14 Diabetes mellitus
0.907 0.093 0.000
S06.5 Traumatic subdural haemorrhage
0.907 0.093 0.000
H52.1 Myopia
0.901 0.099 0.000
N39 Other disorders of urinary system
0.900 0.100 0.000
G43 Migraine
0.899 0.101 0.000
E83 Disorders of mineral metabolism
0.896 0.104 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.894 0.106 0.000
M13 Other arthritis
0.893 0.107 0.000
N60-N64 Disorders of breast
0.890 0.110 0.000
S00.1 Contusion of eyelid and periocular area
0.887 0.113 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.887 0.113 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.886 0.114 0.000
N80.1 Endometriosis of ovary
0.886 0.114 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.884 0.116 0.000
Z42 Follow-up care involving plastic surgery
0.882 0.118 0.000
N80.9 Endometriosis, unspecified
0.882 0.118 0.000
B34 Viral infection of unspecified site
0.881 0.119 0.000
S40-S49 Injuries to the shoulder and upper arm
0.881 0.119 0.000
E86 Volume depletion
0.879 0.121 0.000
S02.0 Fracture of vault of skull
0.876 0.124 0.000
N39.9 Disorder of urinary system, unspecified
0.875 0.125 0.000
Z48.0 Attention to surgical dressings and sutures
0.872 0.128 0.000
E89.0 Postprocedural hypothyroidism
0.871 0.129 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.871 0.129 0.000
C15 Malignant neoplasm of oesophagus
0.870 0.130 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.869 0.131 0.000
O72 Postpartum haemorrhage
0.869 0.131 0.000
Z45 Adjustment and management of implanted device
0.867 0.133 0.000
M79.0 Rheumatism, unspecified
0.863 0.137 0.000
S01.5 Open wound of lip and oral cavity
0.862 0.138 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.861 0.139 0.000
S80-S89 Injuries to the knee and lower leg
0.860 0.140 0.000
C25 Malignant neoplasm of pancreas
0.857 0.143 0.000
N84 Polyp of female genital tract
0.857 0.143 0.000
C50.0 Nipple and areola
0.856 0.144 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.854 0.146 0.000
M79.7 Fibromyalgia
0.853 0.147 0.000
T78 Adverse effects, not elsewhere classified
0.848 0.152 0.000
M65-M68 Disorders of synovium and tendon
0.848 0.152 0.000
N80.3 Endometriosis of pelvic peritoneum
0.847 0.153 0.000
B34.9 Viral infection, unspecified
0.846 0.154 0.000
S01.4 Open wound of cheek and temporomandibular area
0.844 0.155 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.844 0.156 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.842 0.158 0.000
G47.3 Sleep apnoea
0.841 0.159 0.000
M05 Seropositive rheumatoid arthritis
0.840 0.159 0.000
S01.0 Open wound of scalp
0.840 0.160 0.000
C50.1 Central portion of breast
0.840 0.160 0.000
M13.9 Arthritis, unspecified
0.839 0.161 0.000
Z29 Need for other prophylactic measures
0.837 0.163 0.000
H40-H42 Glaucoma
0.837 0.163 0.000
M80-M85 Disorders of bone density and structure
0.833 0.167 0.000
N86 Erosion and ectropion of cervix uteri
0.833 0.167 0.000
H43-H45 Disorders of vitreous body and globe
0.832 0.168 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.832 0.168 0.000
N80.5 Endometriosis of intestine
0.832 0.168 0.000
Z51 Other medical care
0.830 0.170 0.000
E83.1 Disorders of iron metabolism
0.829 0.171 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.827 0.173 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.826 0.174 0.000
O61 Failed induction of labour
0.826 0.174 0.000
S02.1 Fracture of base of skull
0.825 0.175 0.000
N73 Other female pelvic inflammatory diseases
0.821 0.179 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.821 0.179 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.819 0.181 0.000
S06.4 Epidural haemorrhage
0.819 0.181 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.818 0.182 0.000
T78.4 Allergy, unspecified
0.817 0.183 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.813 0.187 0.000
O72.1 Other immediate postpartum haemorrhage
0.813 0.187 0.000
S02.3 Fracture of orbital floor
0.812 0.188 0.000
G93 Other disorders of brain
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.808 0.192 0.000
E11 Non-insulin-dependent diabetes mellitus
0.807 0.193 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.806 0.194 0.000
S02.00 Fracture of vault of skull (closed)
0.806 0.194 0.000
N10-N16 Renal tubulo-interstitial diseases
0.805 0.195 0.000
E10 Insulin-dependent diabetes mellitus
0.805 0.195 0.000
C18.2 Ascending colon
0.804 0.196 0.000
S42 Fracture of shoulder and upper arm
0.804 0.196 0.000
S10-S19 Injuries to the neck
0.803 0.197 0.000
N61 Inflammatory disorders of breast
0.802 0.198 0.000
C50.3 Lower-inner quadrant of breast
0.802 0.198 0.000
M79.1 Myalgia
0.802 0.198 0.000
Z51.0 Radiotherapy session
0.800 0.200 0.000
G44 Other headache syndromes
0.799 0.201 0.000
C50.8 Overlapping lesion of breast
0.797 0.203 0.000
O85-O92 Complications predominantly related to the puerperium
0.795 0.205 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.793 0.207 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.793 0.207 0.000
M10 Gout
0.791 0.209 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.791 0.209 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.789 0.211 0.000
G47.9 Sleep disorder, unspecified
0.788 0.212 0.000
S82 Fracture of lower leg, including ankle
0.787 0.213 0.000
M77 Other enthesopathies
0.787 0.213 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.786 0.213 0.000
S06.3 Focal brain injury
0.784 0.216 0.000
S02.2 Fracture of nasal bones
0.784 0.216 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.783 0.217 0.000
Z45.1 Adjustment and management of infusion pump
0.782 0.218 0.000
S00.0 Superficial injury of scalp
0.781 0.219 0.000
M65 Synovitis and tenosynovitis
0.781 0.219 0.000
C50.4 Upper-outer quadrant of breast
0.780 0.220 0.000
S01.9 Open wound of head, part unspecified
0.779 0.221 0.000
C23 Malignant neoplasm of gallbladder
0.778 0.222 0.000
N88 Other noninflammatory disorders of cervix uteri
0.777 0.223 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
G96 Other disorders of central nervous system
0.773 0.227 0.000
S06.0 Concussion
0.773 0.227 0.000
N39.0 Urinary tract infection, site not specified
0.772 0.228 0.000
N73.6 Female pelvic peritoneal adhesions
0.771 0.229 0.000
O63 Long labour
0.769 0.231 0.000
M79.79 Fibromyalgia (Site unspecified)
0.769 0.231 0.000
G43.1 Migraine with aura [classical migraine]
0.768 0.232 0.000
Z51.1 Chemotherapy session for neoplasm
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.767 0.233 0.000
C18.6 Descending colon
0.767 0.233 0.000
M91-M94 Chondropathies
0.765 0.235 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.765 0.235 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.763 0.237 0.000
T90 Sequelae of injuries of head
0.763 0.237 0.000
N84.0 Polyp of corpus uteri
0.763 0.237 0.000
G43.9 Migraine, unspecified
0.762 0.238 0.000
C51-C58 Malignant neoplasms of female genital organs
0.758 0.242 0.000
N82 Fistulae involving female genital tract
0.757 0.243 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.756 0.244 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.755 0.245 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.754 0.246 0.000
M79.6 Pain in limb
0.754 0.246 0.000
Z29.1 Prophylactic immunotherapy
0.752 0.248 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.752 0.248 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.751 0.249 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.751 0.249 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.750 0.250 0.000
N39.4 Other specified urinary incontinence
0.750 0.250 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.750 0.250 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.749 0.251 0.000
C15.4 Middle third of oesophagus
0.749 0.251 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.749 0.251 0.000
H40 Glaucoma
0.748 0.252 0.000
N63 Unspecified lump in breast
0.747 0.253 0.000
A80-A89 Viral infections of the central nervous system
0.746 0.253 0.000
B99-B99 Other infectious diseases
0.746 0.254 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.745 0.255 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.745 0.255 0.000
C18.1 Appendix
0.744 0.256 0.000
Z44 Fitting and adjustment of external prosthetic device
0.743 0.257 0.000
S01.3 Open wound of ear
0.743 0.257 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.743 0.257 0.000
Z45.2 Adjustment and management of vascular access device
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.259 0.000
O20 Haemorrhage in early pregnancy
0.740 0.260 0.000
M72 Fibroblastic disorders
0.740 0.260 0.000
S06.8 Other intracranial injuries
0.739 0.260 0.000
C25.0 Head of pancreas
0.739 0.261 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.739 0.261 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.738 0.262 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.738 0.262 0.000
N71 Inflammatory disease of uterus, except cervix
0.737 0.263 0.000
A30-A49 Other bacterial diseases
0.734 0.266 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.733 0.267 0.000
S01.7 Multiple open wounds of head
0.731 0.269 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.731 0.269 0.000
S00.7 Multiple superficial injuries of head
0.731 0.269 0.000
C50.2 Upper-inner quadrant of breast
0.730 0.270 0.000
O44 Placenta praevia
0.730 0.270 0.000
O66 Other obstructed labour
0.729 0.271 0.000
N34 Urethritis and urethral syndrome
0.728 0.272 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.728 0.272 0.000
H30-H36 Disorders of choroid and retina
0.728 0.272 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.727 0.273 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.273 0.000
C15.5 Lower third of oesophagus
0.726 0.274 0.000
S02.6 Fracture of mandible
0.726 0.274 0.000
D00-D09 In situ neoplasms
0.724 0.275 0.000
S02.5 Fracture of tooth
0.724 0.276 0.000
N80.2 Endometriosis of Fallopian tube
0.723 0.277 0.000
O61.0 Failed medical induction of labour
0.722 0.278 0.000
N25-N29 Other disorders of kidney and ureter
0.722 0.278 0.000
Z40 Prophylactic surgery
0.722 0.278 0.000
E65-E68 Obesity and other hyperalimentation
0.722 0.278 0.000
H52.0 Hypermetropia
0.722 0.278 0.000
T17 Foreign body in respiratory tract
0.721 0.279 0.000
H44 Disorders of globe
0.720 0.280 0.000
G35 Multiple sclerosis
0.720 0.280 0.000
E11.3 With ophthalmic complications
0.719 0.281 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.719 0.281 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.719 0.281 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.282 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.718 0.282 0.000
S02.10 Fracture of base of skull (closed)
0.718 0.282 0.000
M79.2 Neuralgia and neuritis, unspecified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S05 Injury of eye and orbit
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
N95 Menopausal and other perimenopausal disorders
0.716 0.284 0.000
O62 Abnormalities of forces of labour
0.716 0.284 0.000
N13 Obstructive and reflux uropathy
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
G41 Status epilepticus
0.715 0.285 0.000
Z54 Convalescence
0.715 0.285 0.000
S42.2 Fracture of upper end of humerus
0.714 0.285 0.000
Z52 Donors of organs and tissues
0.714 0.286 0.000
H40.1 Primary open-angle glaucoma
0.714 0.286 0.000
N80.8 Other endometriosis
0.714 0.286 0.000
N39.8 Other specified disorders of urinary system
0.714 0.286 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.288 0.000
B65-B83 Helminthiases
0.711 0.288 0.000
B50-B64 Protozoal diseases
0.711 0.288 0.000
B15-B19 Viral hepatitis
0.711 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.288 0.000
A75-A79 Rickettsioses
0.711 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.288 0.000
A65-A69 Other spirochaetal diseases
0.711 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.288 0.000
A15-A19 Tuberculosis
0.711 0.288 0.000
S00.8 Superficial injury of other parts of head
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.707 0.293 0.000
N91 Absent, scanty and rare menstruation
0.707 0.293 0.000
N96 Habitual aborter
0.707 0.293 0.000
C50.6 Axillary tail of breast
0.707 0.293 0.000
S82.2 Fracture of shaft of tibia
0.706 0.294 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.296 0.000
C17 Malignant neoplasm of small intestine
0.704 0.296 0.000
G40.8 Other epilepsy
0.704 0.296 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.704 0.296 0.000
G40.5 Special epileptic syndromes
0.704 0.296 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.704 0.296 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.704 0.296 0.000
M06 Other rheumatoid arthritis
0.704 0.296 0.000
M15-M19 Arthrosis
0.704 0.296 0.000
S06.9 Intracranial injury, unspecified
0.703 0.297 0.000
S06.7 Intracranial injury with prolonged coma
0.703 0.297 0.000
S06.1 Traumatic cerebral oedema
0.703 0.297 0.000
O75.8 Other specified complications of labour and delivery
0.703 0.297 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.702 0.298 0.000
T92 Sequelae of injuries of upper limb
0.702 0.298 0.000
S01.1 Open wound of eyelid and periocular area
0.702 0.298 0.000
N62 Hypertrophy of breast
0.702 0.298 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.701 0.299 0.000
E83.4 Disorders of magnesium metabolism
0.701 0.299 0.000
G93.8 Other specified disorders of brain
0.700 0.300 0.000
M79.5 Residual foreign body in soft tissue
0.700 0.300 0.000
E40-E46 Malnutrition
0.699 0.300 0.000
S06.2 Diffuse brain injury
0.699 0.301 0.000
N80.6 Endometriosis in cutaneous scar
0.698 0.302 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.698 0.302 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.698 0.302 0.000
S02.8 Fractures of other skull and facial bones
0.698 0.302 0.000
S02.7 Multiple fractures involving skull and facial bones
0.698 0.302 0.000
B25 Cytomegaloviral disease
0.697 0.303 0.000
S02.30 Fracture of orbital floor (closed)
0.697 0.303 0.000
C18.7 Sigmoid colon
0.696 0.304 0.000
H50 Other strabismus
0.696 0.304 0.000
O74 Complications of anaesthesia during labour and delivery
0.696 0.304 0.000
O71 Other obstetric trauma
0.696 0.304 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.696 0.304 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.696 0.304 0.000
O60 Preterm delivery
0.696 0.304 0.000
O48 Prolonged pregnancy
0.695 0.305 0.000
Z22 Carrier of infectious disease
0.695 0.305 0.000
T79-T79 Certain early complications of trauma
0.695 0.305 0.000
M11 Other crystal arthropathies
0.695 0.305 0.000
Z29.8 Other specified prophylactic measures
0.693 0.307 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.693 0.307 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
M14 Arthropathies in other diseases classified elsewhere
0.692 0.307 0.000
M12 Other specific arthropathies
0.692 0.307 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.692 0.307 0.000
M08 Juvenile arthritis
0.692 0.307 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.692 0.308 0.000
E83.3 Disorders of phosphorus metabolism
0.691 0.309 0.000
E11.5 With peripheral circulatory complications
0.690 0.310 0.000
T98 Sequelae of other and unspecified effects of external causes
0.690 0.310 0.000
G37 Other demyelinating diseases of central nervous system
0.690 0.310 0.000
E85 Amyloidosis
0.688 0.312 0.000
E84 Cystic fibrosis
0.688 0.312 0.000
E79 Disorders of purine and pyrimidine metabolism
0.688 0.312 0.000
E77 Disorders of glycoprotein metabolism
0.688 0.312 0.000
E76 Disorders of glycosaminoglycan metabolism
0.688 0.312 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.688 0.312 0.000
E74 Other disorders of carbohydrate metabolism
0.688 0.312 0.000
E73 Lactose intolerance
0.688 0.312 0.000
E72 Other disorders of amino-acid metabolism
0.688 0.312 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.688 0.312 0.000
E70 Disorders of aromatic amino-acid metabolism
0.688 0.312 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.688 0.312 0.000
M76 Enthesopathies of lower limb, excluding foot
0.687 0.313 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.687 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
M79.19 Myalgia (Site unspecified)
0.685 0.315 0.000
C64-C68 Malignant neoplasms of urinary tract
0.684 0.316 0.000
S00.5 Superficial injury of lip and oral cavity
0.684 0.316 0.000
S00.4 Superficial injury of ear
0.684 0.316 0.000
S00.3 Superficial injury of nose
0.684 0.316 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.684 0.316 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.684 0.316 0.000
C18.3 Hepatic flexure
0.684 0.316 0.000
G93.0 Cerebral cysts
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.683 0.317 0.000
G20-G26 Extrapyramidal and movement disorders
0.682 0.318 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.682 0.318 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.679 0.320 0.000
C71 Malignant neoplasm of brain
0.679 0.321 0.000
G47.8 Other sleep disorders
0.678 0.321 0.000
G47.4 Narcolepsy and cataplexy
0.678 0.321 0.000
G47.2 Disorders of the sleep-wake schedule
0.678 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.678 0.321 0.000
T81 Complications of procedures, not elsewhere classified
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.323 0.000
S00.9 Superficial injury of head, part unspecified
0.676 0.324 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.675 0.325 0.000
G96.0 Cerebrospinal fluid leak
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.675 0.325 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.675 0.325 0.000
M79.3 Panniculitis, unspecified
0.675 0.325 0.000
N75 Diseases of Bartholin's gland
0.675 0.325 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.674 0.326 0.000
G95 Other diseases of spinal cord
0.673 0.327 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.673 0.327 0.000
M79.70 Fibromyalgia (Multiple sites)
0.672 0.328 0.000
C25.9 Pancreas, unspecified
0.671 0.329 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.671 0.329 0.000
H51 Other disorders of binocular movement
0.671 0.329 0.000
H49 Paralytic strabismus
0.671 0.329 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.670 0.330 0.000
M84 Disorders of continuity of bone
0.669 0.331 0.000
A00-A09 Intestinal infectious diseases
0.669 0.331 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.669 0.331 0.000
O20.0 Threatened abortion
0.668 0.332 0.000
B33 Other viral diseases, not elsewhere classified
0.667 0.332 0.000
B30 Viral conjunctivitis
0.667 0.332 0.000
B27 Infectious mononucleosis
0.667 0.332 0.000
B26 Mumps
0.667 0.332 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.667 0.333 0.000
O73 Retained placenta and membranes, without haemorrhage
0.667 0.333 0.000
S02.4 Fracture of malar and maxillary bones
0.666 0.334 0.000
M10.9 Gout, unspecified
0.666 0.334 0.000
Chapter VIII Diseases of the ear and mastoid process
0.665 0.335 0.000
H36 Retinal disorders in diseases classified elsewhere
0.664 0.336 0.000
G44.0 Cluster headache syndrome
0.664 0.336 0.000
C18.4 Transverse colon
0.664 0.336 0.000
N00-N08 Glomerular diseases
0.663 0.337 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.662 0.338 0.000
M79.60 Pain in limb (Multiple sites)
0.662 0.338 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.661 0.339 0.000
M40-M43 Deforming dorsopathies
0.661 0.339 0.000
E20-E35 Disorders of other endocrine glands
0.661 0.339 0.000
S01.2 Open wound of nose
0.660 0.339 0.000
Z41 Procedures for purposes other than remedying health state
0.659 0.341 0.000
H52.2 Astigmatism
0.658 0.342 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.658 0.342 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.658 0.342 0.000
S82.4 Fracture of fibula alone
0.658 0.342 0.000
H52.7 Disorder of refraction, unspecified
0.657 0.343 0.000
H52.6 Other disorders of refraction
0.657 0.343 0.000
H52.5 Disorders of accommodation
0.657 0.343 0.000
H52.4 Presbyopia
0.657 0.343 0.000
M85 Other disorders of bone density and structure
0.656 0.344 0.000
S81 Open wound of lower leg
0.656 0.344 0.000
S20 Superficial injury of thorax
0.656 0.344 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.655 0.345 0.000
N37 Urethral disorders in diseases classified elsewhere
0.655 0.345 0.000
N33 Bladder disorders in diseases classified elsewhere
0.655 0.345 0.000
N30 Cystitis
0.654 0.346 0.000
E11.2 With renal complications
0.654 0.346 0.000
B35-B49 Mycoses
0.653 0.346 0.000
T75 Effects of other external causes
0.653 0.347 0.000
T74 Maltreatment syndromes
0.653 0.347 0.000
T73 Effects of other deprivation
0.653 0.347 0.000
T70 Effects of air pressure and water pressure
0.653 0.347 0.000
T69 Other effects of reduced temperature
0.653 0.347 0.000
T67 Effects of heat and light
0.653 0.347 0.000
T71 Asphyxiation
0.653 0.347 0.000
T68 Hypothermia
0.653 0.347 0.000
T66 Unspecified effects of radiation
0.653 0.347 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.653 0.347 0.000
Z29.2 Other prophylactic chemotherapy
0.653 0.347 0.000
O46.9 Antepartum haemorrhage, unspecified
0.653 0.347 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.652 0.348 0.000
G90 Disorders of autonomic nervous system
0.652 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
C18.8 Overlapping lesion of colon
0.652 0.348 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.652 0.348 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.652 0.348 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.651 0.349 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.651 0.349 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.651 0.349 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.651 0.349 0.000
E89.5 Postprocedural testicular hypofunction
0.651 0.349 0.000
E89.4 Postprocedural ovarian failure
0.651 0.349 0.000
E89.3 Postprocedural hypopituitarism
0.651 0.349 0.000
E89.2 Postprocedural hypoparathyroidism
0.651 0.349 0.000
E89.1 Postprocedural hypoinsulinaemia
0.651 0.349 0.000
S42.20 Fracture of upper end of humerus (closed)
0.651 0.349 0.000
E13 Other specified diabetes mellitus
0.651 0.349 0.000
E12 Malnutrition-related diabetes mellitus
0.651 0.349 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.650 0.350 0.000
S82.1 Fracture of upper end of tibia
0.649 0.351 0.000
S02.20 Fracture of nasal bones (closed)
0.649 0.351 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.647 0.353 0.000
M13.0 Polyarthritis, unspecified
0.646 0.353 0.000
B91 Sequelae of poliomyelitis
0.646 0.353 0.000
Z47 Other orthopaedic follow-up care
0.646 0.354 0.000
M71 Other bursopathies
0.645 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.645 0.355 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.645 0.355 0.000
N39.2 Orthostatic proteinuria, unspecified
0.645 0.355 0.000
N39.1 Persistent proteinuria, unspecified
0.645 0.355 0.000
Z50 Care involving use of rehabilitation procedures
0.645 0.355 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.644 0.355 0.000
G43.8 Other migraine
0.644 0.356 0.000
G43.3 Complicated migraine
0.644 0.356 0.000
G43.2 Status migrainosus
0.644 0.356 0.000
G43.0 Migraine without aura [common migraine]
0.644 0.356 0.000
M82 Osteoporosis in diseases classified elsewhere
0.644 0.356 0.000
E10.3 With ophthalmic complications
0.644 0.356 0.000
D45 Polycythaemia vera
0.644 0.356 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.643 0.357 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.643 0.357 0.000
E83.8 Other disorders of mineral metabolism
0.643 0.357 0.000
E83.2 Disorders of zinc metabolism
0.643 0.357 0.000
E83.0 Disorders of copper metabolism
0.643 0.357 0.000
C16 Malignant neoplasm of stomach
0.643 0.357 0.000
O00-O08 Pregnancy with abortive outcome
0.642 0.358 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.641 0.359 0.000
Z28 Immunisation not carried out
0.641 0.359 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.641 0.359 0.000
Z26 Need for immunisation against other single infectious diseases
0.641 0.359 0.000
Z25 Need for immunisation against other single viral diseases
0.641 0.359 0.000
Z24 Need for immunisation against certain single viral diseases
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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