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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76444916
log Bayes Factor = 7.67221
Chromosome 4   position 179,708,829  (GRCh37) Explore rs76444916 on Ensembl!
Variant rs76444916 is part of Cluster X0013

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
O63 Long labour
0.982 0.018 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
S00 Superficial injury of head
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.964 0.036 0.000
O63.1 Prolonged second stage (of labour)
0.958 0.042 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.955 0.045 0.000
S00.8 Superficial injury of other parts of head
0.954 0.046 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.947 0.053 0.000
S01 Open wound of head
0.947 0.053 0.000
F30-F39 Mood [affective] disorders
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.945 0.055 0.000
T66-T78 Other and unspecified effects of external causes
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.938 0.062 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.934 0.066 0.000
F31 Bipolar affective disorder
0.934 0.066 0.000
S06 Intracranial injury
0.934 0.066 0.000
S02 Fracture of skull and facial bones
0.932 0.068 0.000
E00-E07 Disorders of thyroid gland
0.925 0.075 0.000
J00-J06 Acute upper respiratory infections
0.922 0.078 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.919 0.081 0.000
Chapter XXII Codes for special purposes
0.919 0.081 0.000
G40 Epilepsy
0.919 0.081 0.000
H65-H75 Diseases of middle ear and mastoid
0.916 0.084 0.000
G40-G47 Episodic and paroxysmal disorders
0.915 0.085 0.000
F31.9 Bipolar affective disorder, unspecified
0.914 0.086 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.911 0.089 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.908 0.092 0.000
S01.9 Open wound of head, part unspecified
0.899 0.101 0.000
G90-G99 Other disorders of the nervous system
0.898 0.102 0.000
E50-E64 Other nutritional deficiencies
0.897 0.103 0.000
T78 Adverse effects, not elsewhere classified
0.897 0.103 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.894 0.106 0.000
G40.9 Epilepsy, unspecified
0.889 0.111 0.000
E20-E35 Disorders of other endocrine glands
0.887 0.113 0.000
S06.5 Traumatic subdural haemorrhage
0.878 0.122 0.000
J30-J39 Other diseases of upper respiratory tract
0.870 0.130 0.000
J84 Other interstitial pulmonary diseases
0.869 0.131 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.868 0.132 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.868 0.132 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.862 0.138 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.861 0.139 0.000
S80-S89 Injuries to the knee and lower leg
0.861 0.139 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.859 0.140 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.856 0.144 0.000
F10.1 Harmful use
0.856 0.144 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.851 0.149 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.848 0.152 0.000
T91 Sequelae of injuries of neck and trunk
0.847 0.153 0.000
H60-H62 Diseases of external ear
0.846 0.154 0.000
H73 Other disorders of tympanic membrane
0.845 0.155 0.000
E61 Deficiency of other nutrient elements
0.840 0.159 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.839 0.161 0.000
O70 Perineal laceration during delivery
0.838 0.162 0.000
O66 Other obstructed labour
0.836 0.164 0.000
E05.9 Thyrotoxicosis, unspecified
0.836 0.164 0.000
S01.3 Open wound of ear
0.835 0.165 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.835 0.165 0.000
U80 Agent resistant to penicillin and related antibiotics
0.828 0.172 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.826 0.174 0.000
O63.0 Prolonged first stage (of labour)
0.825 0.175 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.825 0.175 0.000
O85-O92 Complications predominantly related to the puerperium
0.825 0.175 0.000
T78.2 Anaphylactic shock, unspecified
0.823 0.177 0.000
S90-S99 Injuries to the ankle and foot
0.823 0.177 0.000
J33 Nasal polyp
0.822 0.178 0.000
G93 Other disorders of brain
0.822 0.178 0.000
J60-J70 Lung diseases due to external agents
0.822 0.178 0.000
Y00-Y09 Assault
0.819 0.181 0.000
W00-W19 Falls
0.817 0.183 0.000
J00 Acute nasopharyngitis [common cold]
0.817 0.183 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.816 0.184 0.000
H80-H83 Diseases of inner ear
0.815 0.185 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.815 0.185 0.000
H72 Perforation of tympanic membrane
0.813 0.187 0.000
S02.4 Fracture of malar and maxillary bones
0.811 0.189 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.807 0.193 0.000
E61.1 Iron deficiency
0.800 0.200 0.000
S82 Fracture of lower leg, including ankle
0.799 0.201 0.000
S01.0 Open wound of scalp
0.798 0.202 0.000
W20-W49 Exposure to inanimate mechanical forces
0.797 0.203 0.000
H90-H95 Other disorders of ear
0.796 0.204 0.000
T92 Sequelae of injuries of upper limb
0.796 0.204 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.796 0.204 0.000
H73.8 Other specified disorders of tympanic membrane
0.795 0.205 0.000
X60-X84 Intentional self-harm
0.795 0.205 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.794 0.206 0.000
E03 Other hypothyroidism
0.792 0.208 0.000
O80-O84 Delivery
0.787 0.213 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.786 0.214 0.000
S02.8 Fractures of other skull and facial bones
0.785 0.215 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.782 0.218 0.000
Y86 Sequelae of other accidents
0.781 0.219 0.000
H71 Cholesteatoma of middle ear
0.779 0.221 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.777 0.223 0.000
G95 Other diseases of spinal cord
0.776 0.224 0.000
O26.8 Other specified pregnancy-related conditions
0.776 0.224 0.000
S60-S69 Injuries to the wrist and hand
0.773 0.226 0.000
U80.1 Methicillin resistant agent
0.774 0.226 0.000
J20-J22 Other acute lower respiratory infections
0.773 0.227 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.772 0.228 0.000
Y95 Nosocomial condition
0.770 0.230 0.000
F10.2 Dependence syndrome
0.770 0.230 0.000
G96 Other disorders of central nervous system
0.767 0.233 0.000
S82.6 Fracture of lateral malleolus
0.767 0.233 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.767 0.233 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.765 0.234 0.000
S02.1 Fracture of base of skull
0.764 0.236 0.000
T78.4 Allergy, unspecified
0.763 0.237 0.000
J81 Pulmonary oedema
0.763 0.237 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.762 0.238 0.000
V10-V19 Pedal cyclist injured in transport accident
0.756 0.244 0.000
J06.9 Acute upper respiratory infection, unspecified
0.755 0.245 0.000
F10.0 Acute intoxication
0.754 0.246 0.000
S02.0 Fracture of vault of skull
0.754 0.246 0.000
F30 Manic episode
0.753 0.247 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.753 0.247 0.000
S00.9 Superficial injury of head, part unspecified
0.753 0.247 0.000
J01 Acute sinusitis
0.753 0.247 0.000
S00.0 Superficial injury of scalp
0.752 0.248 0.000
T93 Sequelae of injuries of lower limb
0.751 0.249 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.751 0.249 0.000
F70-F79 Mental retardation
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.748 0.252 0.000
G40.5 Special epileptic syndromes
0.745 0.255 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.745 0.255 0.000
O70.0 First degree perineal laceration during delivery
0.744 0.256 0.000
S82.60 Fracture of lateral malleolus (closed)
0.744 0.256 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.741 0.259 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.740 0.260 0.000
J33.8 Other polyp of sinus
0.740 0.260 0.000
X20-X29 Contact with venomous animals and plants
0.737 0.263 0.000
O73 Retained placenta and membranes, without haemorrhage
0.736 0.264 0.000
S05 Injury of eye and orbit
0.735 0.265 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.735 0.265 0.000
S06.3 Focal brain injury
0.735 0.265 0.000
O63.9 Long labour, unspecified
0.734 0.266 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.734 0.266 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
J33.0 Polyp of nasal cavity
0.733 0.267 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
F80-F89 Disorders of psychological development
0.729 0.271 0.000
S60 Superficial injury of wrist and hand
0.729 0.271 0.000
E06 Thyroiditis
0.727 0.273 0.000
V40-V49 Car occupant injured in transport accident
0.726 0.273 0.000
E27 Other disorders of adrenal gland
0.726 0.274 0.000
E23 Hypofunction and other disorders of pituitary gland
0.724 0.276 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.723 0.277 0.000
J39 Other diseases of upper respiratory tract
0.723 0.277 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.721 0.279 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O71 Other obstetric trauma
0.717 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
T68 Hypothermia
0.716 0.284 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.716 0.284 0.000
J35 Chronic diseases of tonsils and adenoids
0.715 0.285 0.000
O30 Multiple gestation
0.715 0.285 0.000
H90 Conductive and sensorineural hearing loss
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.288 0.000
G93.8 Other specified disorders of brain
0.711 0.289 0.000
S06.9 Intracranial injury, unspecified
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.291 0.000
Y10-Y34 Event of undetermined intent
0.708 0.291 0.000
X85-X99 Assault
0.708 0.291 0.000
X50-X57 Overexertion, travel and privation
0.708 0.291 0.000
X30-X39 Exposure to forces of nature
0.708 0.291 0.000
X10-X19 Contact with heat and hot substances
0.708 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.291 0.000
W75-W84 Other accidental threats to breathing
0.708 0.291 0.000
W65-W74 Accidental drowning and submersion
0.708 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.291 0.000
V95-V97 Air and space transport accidents
0.708 0.291 0.000
V90-V94 Water transport accidents
0.708 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.291 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.704 0.296 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
O28 Abnormal findings on antenatal screening of mother
0.703 0.297 0.000
T91.3 Sequelae of injury of spinal cord
0.703 0.297 0.000
H61 Other disorders of external ear
0.703 0.297 0.000
Y89 Sequelae of other external causes
0.703 0.297 0.000
S00.1 Contusion of eyelid and periocular area
0.703 0.297 0.000
G91 Hydrocephalus
0.701 0.298 0.000
F52.2 Failure of genital response
0.701 0.299 0.000
S00.5 Superficial injury of lip and oral cavity
0.700 0.300 0.000
S00.4 Superficial injury of ear
0.700 0.300 0.000
O86 Other puerperal infections
0.699 0.301 0.000
S00.3 Superficial injury of nose
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.301 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.698 0.302 0.000
E20 Hypoparathyroidism
0.698 0.302 0.000
S06.4 Epidural haemorrhage
0.698 0.302 0.000
J80 Adult respiratory distress syndrome
0.697 0.303 0.000
T98 Sequelae of other and unspecified effects of external causes
0.697 0.303 0.000
W07 Fall involving chair
0.696 0.304 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.696 0.304 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.695 0.305 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.695 0.305 0.000
J37 Chronic laryngitis and laryngotracheitis
0.695 0.305 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.694 0.306 0.000
Q00-Q07 Congenital malformations of the nervous system
0.693 0.307 0.000
J40-J47 Chronic lower respiratory diseases
0.691 0.309 0.000
O62 Abnormalities of forces of labour
0.691 0.309 0.000
S09 Other and unspecified injuries of head
0.691 0.309 0.000
H66 Suppurative and unspecified otitis media
0.691 0.309 0.000
O43 Placental disorders
0.690 0.310 0.000
O70.2 Third degree perineal laceration during delivery
0.689 0.311 0.000
E53 Deficiency of other B group vitamins
0.688 0.312 0.000
E04 Other non-toxic goitre
0.688 0.312 0.000
S02.6 Fracture of mandible
0.687 0.313 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.686 0.313 0.000
E29 Testicular dysfunction
0.686 0.314 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.685 0.315 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.685 0.315 0.000
O69.3 Labour and delivery complicated by short cord
0.685 0.315 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.685 0.315 0.000
H60 Otitis externa
0.683 0.317 0.000
E40-E46 Malnutrition
0.683 0.317 0.000
F33 Recurrent depressive disorder
0.683 0.317 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.683 0.317 0.000
H72.2 Other marginal perforations of tympanic membrane
0.683 0.317 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.682 0.317 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.679 0.321 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.679 0.321 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.679 0.321 0.000
F38 Other mood [affective] disorders
0.679 0.321 0.000
F34 Persistent mood [affective] disorders
0.679 0.321 0.000
F39 Unspecified mood [affective] disorder
0.679 0.321 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.679 0.321 0.000
H80 Otosclerosis
0.678 0.322 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.322 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.322 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
T75 Effects of other external causes
0.677 0.323 0.000
T74 Maltreatment syndromes
0.677 0.323 0.000
T73 Effects of other deprivation
0.677 0.323 0.000
T70 Effects of air pressure and water pressure
0.677 0.323 0.000
T69 Other effects of reduced temperature
0.677 0.323 0.000
T67 Effects of heat and light
0.677 0.323 0.000
T71 Asphyxiation
0.677 0.323 0.000
T66 Unspecified effects of radiation
0.677 0.323 0.000
F60-F69 Disorders of adult personality and behaviour
0.676 0.323 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.676 0.324 0.000
S01.8 Open wound of other parts of head
0.676 0.324 0.000
J04 Acute laryngitis and tracheitis
0.676 0.324 0.000
S60.8 Other superficial injuries of wrist and hand
0.675 0.325 0.000
S19 Other and unspecified injuries of neck
0.675 0.325 0.000
T91.1 Sequelae of fracture of spine
0.674 0.326 0.000
E26 Hyperaldosteronism
0.674 0.326 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.674 0.326 0.000
S02.3 Fracture of orbital floor
0.672 0.328 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.672 0.328 0.000
E34 Other endocrine disorders
0.671 0.329 0.000
J20 Acute bronchitis
0.671 0.329 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.670 0.330 0.000
F31.8 Other bipolar affective disorders
0.670 0.330 0.000
F31.7 Bipolar affective disorder, currently in remission
0.670 0.330 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.670 0.330 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.670 0.330 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.670 0.330 0.000
O24 Diabetes mellitus in pregnancy
0.669 0.330 0.000
S06.7 Intracranial injury with prolonged coma
0.669 0.331 0.000
S06.1 Traumatic cerebral oedema
0.669 0.331 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.668 0.332 0.000
S02.7 Multiple fractures involving skull and facial bones
0.668 0.332 0.000
E03.9 Hypothyroidism, unspecified
0.668 0.332 0.000
G96.0 Cerebrospinal fluid leak
0.667 0.332 0.000
S06.8 Other intracranial injuries
0.667 0.332 0.000
O69.8 Labour and delivery complicated by other cord complications
0.667 0.333 0.000
G93.6 Cerebral oedema
0.665 0.335 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.663 0.337 0.000
E00 Congenital iodine-deficiency syndrome
0.663 0.337 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.663 0.337 0.000
G95.9 Disease of spinal cord, unspecified
0.663 0.337 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.663 0.337 0.000
O21 Excessive vomiting in pregnancy
0.663 0.337 0.000
O41 Other disorders of amniotic fluid and membranes
0.662 0.338 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.661 0.339 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.661 0.339 0.000
O61 Failed induction of labour
0.661 0.339 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.660 0.340 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.659 0.341 0.000
G40.8 Other epilepsy
0.659 0.341 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.659 0.341 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.659 0.341 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.659 0.341 0.000
H81 Disorders of vestibular function
0.658 0.342 0.000
O44 Placenta praevia
0.657 0.343 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.657 0.343 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.656 0.344 0.000
H70 Mastoiditis and related conditions
0.656 0.344 0.000
H68 Eustachian salpingitis and obstruction
0.656 0.344 0.000
H67 Otitis media in diseases classified elsewhere
0.656 0.344 0.000
M15-M19 Arthrosis
0.656 0.344 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.656 0.344 0.000
Y04 Assault by bodily force
0.654 0.345 0.000
S67 Crushing injury of wrist and hand
0.654 0.346 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.653 0.347 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.653 0.347 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.653 0.347 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.653 0.347 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.653 0.347 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.653 0.347 0.000
F11 Mental and behavioural disorders due to use of opioids
0.653 0.347 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.653 0.347 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.652 0.348 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.652 0.348 0.000
J44 Other chronic obstructive pulmonary disease
0.652 0.348 0.000
J30 Vasomotor and allergic rhinitis
0.651 0.349 0.000
O29 Complications of anaesthesia during pregnancy
0.651 0.349 0.000
O23 Infections of genito-urinary tract in pregnancy
0.651 0.349 0.000
O22 Venous complications in pregnancy
0.651 0.349 0.000
O25 Malnutrition in pregnancy
0.651 0.349 0.000
S82.2 Fracture of shaft of tibia
0.651 0.349 0.000
M20-M25 Other joint disorders
0.650 0.350 0.000
O40 Polyhydramnios
0.650 0.350 0.000
G95.8 Other specified diseases of spinal cord
0.650 0.350 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.650 0.350 0.000
Y00 Assault by blunt object
0.649 0.351 0.000
O20 Haemorrhage in early pregnancy
0.647 0.353 0.000
S06.2 Diffuse brain injury
0.646 0.353 0.000
S91 Open wound of ankle and foot
0.646 0.354 0.000
M91-M94 Chondropathies
0.645 0.355 0.000
S80 Superficial injury of lower leg
0.645 0.355 0.000
S01.1 Open wound of eyelid and periocular area
0.644 0.356 0.000
S02.10 Fracture of base of skull (closed)
0.644 0.356 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.644 0.356 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.644 0.356 0.000
G92 Toxic encephalopathy
0.644 0.356 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.643 0.356 0.000
E63 Other nutritional deficiencies
0.643 0.356 0.000
E56 Other vitamin deficiencies
0.643 0.356 0.000
E51 Thiamine deficiency
0.643 0.356 0.000
E50 Vitamin A deficiency
0.643 0.356 0.000
E60 Dietary zinc deficiency
0.643 0.356 0.000
E59 Dietary selenium deficiency
0.643 0.356 0.000
E58 Dietary calcium deficiency
0.643 0.356 0.000
E54 Ascorbic acid deficiency
0.643 0.356 0.000
E52 Niacin deficiency [pellagra]
0.643 0.356 0.000
U51 Admission status on psychiatric patients
0.643 0.357 0.000
S90 Superficial injury of ankle and foot
0.643 0.357 0.000
T78.9 Adverse effect, unspecified
0.643 0.357 0.000
T78.8 Other adverse effects, not elsewhere classified
0.643 0.357 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.642 0.358 0.000
S00.7 Multiple superficial injuries of head
0.642 0.358 0.000
M60-M63 Disorders of muscles
0.641 0.359 0.000
G82 Paraplegia and tetraplegia
0.641 0.359 0.000
F10.9 Unspecified mental and behavioural disorder
0.641 0.359 0.000
F10.8 Other mental and behavioural disorders
0.641 0.359 0.000
F10.7 Residual and late-onset psychotic disorder
0.641 0.359 0.000
F10.6 Amnesic syndrome
0.641 0.359 0.000
F10.5 Psychotic disorder
0.641 0.359 0.000
F10.4 Withdrawal state with delirium
0.641 0.359 0.000
M40-M43 Deforming dorsopathies
0.640 0.360 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.640 0.360 0.000
O80 Single spontaneous delivery
0.640 0.360 0.000
M25 Other joint disorders, not elsewhere classified
0.639 0.361 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.637 0.363 0.000
E55 Vitamin D deficiency
0.637 0.363 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.636 0.364 0.000
E32 Diseases of thymus
0.636 0.364 0.000
E31 Polyglandular dysfunction
0.636 0.364 0.000
E30 Disorders of puberty, not elsewhere classified
0.636 0.364 0.000
E25 Adrenogenital disorders
0.636 0.364 0.000
E24 Cushing's syndrome
0.636 0.364 0.000
W22 Striking against or struck by other objects
0.636 0.364 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.635 0.365 0.000
O81 Single delivery by forceps and vacuum extractor
0.634 0.365 0.000
W29 Contact with other powered hand tools and household machinery
0.634 0.366 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.633 0.366 0.000
G90 Disorders of autonomic nervous system
0.633 0.367 0.000
O47 False labour
0.633 0.367 0.000
J69 Pneumonitis due to solids and liquids
0.632 0.368 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.632 0.368 0.000
J01.9 Acute sinusitis, unspecified
0.631 0.368 0.000
Q80-Q89 Other congenital malformations
0.631 0.369 0.000
H72.0 Central perforation of tympanic membrane
0.630 0.370 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.630 0.370 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.630 0.370 0.000
M25.5 Pain in joint
0.627 0.373 0.000
S12 Fracture of neck
0.626 0.373 0.000
S02.00 Fracture of vault of skull (closed)
0.626 0.374 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.625 0.375 0.000
H69 Other disorders of Eustachian tube
0.625 0.375 0.000
S32 Fracture of lumbar spine and pelvis
0.625 0.375 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.624 0.376 0.000
G41 Status epilepticus
0.624 0.376 0.000
J84.8 Other specified interstitial pulmonary diseases
0.623 0.377 0.000
J84.0 Alveolar and parietoalveolar conditions
0.623 0.377 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.622 0.377 0.000
Y98 Lifestyle-related condition
0.622 0.377 0.000
Y97 Environmental-pollution-related condition
0.622 0.377 0.000
Y96 Work-related condition
0.622 0.377 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.622 0.378 0.000
U50 Level of care administered to neonates
0.622 0.378 0.000
U07 Emergency use of U07
0.622 0.378 0.000
U06 Emergency use of U06
0.622 0.378 0.000
U04 Severe acute respiratory syndrome [SARS]
0.622 0.378 0.000
U52 First in a series of a regular day/night admissions
0.622 0.378 0.000
S01.7 Multiple open wounds of head
0.622 0.378 0.000
Q60-Q64 Congenital malformations of the urinary system
0.622 0.378 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.622 0.378 0.000
G70-G73 Diseases of myoneural junction and muscle
0.621 0.379 0.000
T92.1 Sequelae of fracture of arm
0.620 0.380 0.000
E22 Hyperfunction of pituitary gland
0.619 0.381 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.619 0.381 0.000
E03.8 Other specified hypothyroidism
0.618 0.382 0.000
E05.8 Other thyrotoxicosis
0.618 0.382 0.000
E05.5 Thyroid crisis or storm
0.618 0.382 0.000
E05.4 Thyrotoxicosis factitia
0.618 0.382 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.618 0.382 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.618 0.382 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.618 0.382 0.000
O45 Premature separation of placenta [abruptio placentae]
0.618 0.382 0.000
O33 Maternal care for known or suspected disproportion
0.618 0.382 0.000
O31 Complications specific to multiple gestation
0.618 0.382 0.000
S88 Traumatic amputation of lower leg
0.617 0.383 0.000
S87 Crushing injury of lower leg
0.617 0.383 0.000
S86 Injury of muscle and tendon at lower leg level
0.617 0.383 0.000
S85 Injury of blood vessels at lower leg level
0.617 0.383 0.000
S84 Injury of nerves at lower leg level
0.617 0.383 0.000
S01.2 Open wound of nose
0.616 0.384 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.616 0.384 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.616 0.384 0.000
G93.9 Disorder of brain, unspecified
0.615 0.385 0.000
M25.51 Pain in joint (Shoulder region)
0.615 0.385 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.615 0.385 0.000
F30.9 Manic episode, unspecified
0.615 0.385 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.614 0.386 0.000
F51 Nonorganic sleep disorders
0.614 0.386 0.000
F50 Eating disorders
0.614 0.386 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.614 0.386 0.000
F55 Abuse of non-dependence-producing substances
0.614 0.386 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.614 0.386 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.612 0.387 0.000
J42 Unspecified chronic bronchitis
0.612 0.388 0.000
U80.0 Penicillin resistant agent
0.612 0.388 0.000
T94.1 Sequelae of injuries, not specified by body region
0.612 0.388 0.000
E23.2 Diabetes insipidus
0.612 0.388 0.000
J35.1 Hypertrophy of tonsils
0.611 0.389 0.000
G93.4 Encephalopathy, unspecified
0.610 0.390 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.610 0.390 0.000
Q35-Q37 Cleft lip and cleft palate
0.610 0.390 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.610 0.390 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.610 0.390 0.000
S37 Injury of urinary and pelvic organs
0.610 0.390 0.000
S36 Injury of intra-abdominal organs
0.610 0.390 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.610 0.390 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.610 0.390 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.610 0.390 0.000
S31 Open wound of abdomen, lower back and pelvis
0.610 0.390 0.000
S82.5 Fracture of medial malleolus
0.610 0.390 0.000
O30.0 Twin pregnancy
0.609 0.391 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.608 0.392 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.608 0.392 0.000
S17 Crushing injury of neck
0.608 0.392 0.000
S15 Injury of blood vessels at neck level
0.608 0.392 0.000
S14 Injury of nerves and spinal cord at neck level
0.608 0.392 0.000
S11 Open wound of neck
0.608 0.392 0.000
S18 Traumatic amputation at neck level
0.608 0.392 0.000
S16 Injury of muscle and tendon at neck level
0.608 0.392 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.607 0.392 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.607 0.393 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.607 0.393 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.607 0.393 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.607 0.393 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.607 0.393 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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