TreeWAS – Variant ID: rs76507695

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.096	0.904	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.096	0.904	0.000
Chapter VII Diseases of the eye and adnexa	0.093	0.907	0.000
M70-M79 Other soft tissue disorders	0.093	0.907	0.000
Chapter IX Diseases of the circulatory system	0.091	0.909	0.000
M75 Shoulder lesions	0.091	0.909	0.000
Chapter II Neoplasms	0.088	0.912	0.000
I30-I52 Other forms of heart disease	0.088	0.912	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.087	0.913	0.000
Chapter V Mental and behavioural disorders	0.087	0.913	0.000
M05-M14 Inflammatory polyarthropathies	0.085	0.915	0.000
H30-H36 Disorders of choroid and retina	0.083	0.917	0.000
M75.1 Rotator cuff syndrome	0.082	0.918	0.000
M75.4 Impingement syndrome of shoulder	0.081	0.919	0.000
M20-M25 Other joint disorders	0.081	0.919	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.081	0.919	0.000
I44 Atrioventricular and left bundle-branch block	0.080	0.920	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.080	0.920	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.078	0.922	0.000
C15-C26 Malignant neoplasms of digestive organs	0.077	0.922	0.000
Chapter I Certain infectious and parasitic diseases	0.077	0.923	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.077	0.923	0.000
I60-I69 Cerebrovascular diseases	0.077	0.923	0.000
H25-H28 Disorders of lens	0.076	0.924	0.000
E70-E90 Metabolic disorders	0.074	0.926	0.000
C44 Other malignant neoplasms of skin	0.074	0.926	0.000
I49 Other cardiac arrhythmias	0.074	0.926	0.000
I20-I25 Ischaemic heart diseases	0.074	0.926	0.000
M13 Other arthritis	0.074	0.926	0.000
Chapter XX External causes of morbidity and mortality	0.074	0.926	0.000
H33 Retinal detachments and breaks	0.074	0.926	0.000
H53-H54 Visual disturbances and blindness	0.073	0.927	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.073	0.927	0.000
M80-M85 Disorders of bone density and structure	0.073	0.927	0.000
Chapter VIII Diseases of the ear and mastoid process	0.073	0.927	0.000
M75.5 Bursitis of shoulder	0.073	0.927	0.000
I44.7 Left bundle-branch block, unspecified	0.073	0.927	0.000
M23 Internal derangement of knee	0.072	0.928	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.072	0.928	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.072	0.928	0.000
M75.0 Adhesive capsulitis of shoulder	0.072	0.928	0.000
F30-F39 Mood [affective] disorders	0.071	0.929	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.070	0.929	0.000
O00-O08 Pregnancy with abortive outcome	0.070	0.930	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.070	0.930	0.000
M65-M68 Disorders of synovium and tendon	0.069	0.931	0.000
I45 Other conduction disorders	0.069	0.931	0.000
Chapter XXII Codes for special purposes	0.069	0.931	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.069	0.931	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.069	0.931	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.069	0.931	0.000
M91-M94 Chondropathies	0.069	0.931	0.000
M86-M90 Other osteopathies	0.069	0.931	0.000
M60-M63 Disorders of muscles	0.069	0.931	0.000
M40-M43 Deforming dorsopathies	0.069	0.931	0.000
M00-M03 Infectious arthropathies	0.069	0.931	0.000
I51 Complications and ill-defined descriptions of heart disease	0.068	0.932	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.068	0.932	0.000
M06 Other rheumatoid arthritis	0.068	0.932	0.000
D10-D36 Benign neoplasms	0.067	0.932	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.067	0.933	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.067	0.933	0.000
C64-C68 Malignant neoplasms of urinary tract	0.067	0.933	0.000
H55-H59 Other disorders of eye and adnexa	0.067	0.933	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.067	0.933	0.000
H43-H45 Disorders of vitreous body and globe	0.067	0.933	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.067	0.933	0.000
H10-H13 Disorders of conjunctiva	0.067	0.933	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.067	0.933	0.000
M77 Other enthesopathies	0.067	0.933	0.000
M76 Enthesopathies of lower limb, excluding foot	0.067	0.933	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.067	0.933	0.000
M72 Fibroblastic disorders	0.067	0.933	0.000
M71 Other bursopathies	0.067	0.933	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.067	0.933	0.000
M13.9 Arthritis, unspecified	0.066	0.934	0.000
H35 Other retinal disorders	0.066	0.934	0.000
H33.3 Retinal breaks without detachment	0.066	0.934	0.000
O80-O84 Delivery	0.066	0.934	0.000
I05-I09 Chronic rheumatic heart diseases	0.066	0.934	0.000
I00-I02 Acute rheumatic fever	0.066	0.934	0.000
M75.8 Other shoulder lesions	0.065	0.934	0.000
M75.9 Shoulder lesion, unspecified	0.065	0.934	0.000
M75.3 Calcific tendinitis of shoulder	0.065	0.934	0.000
M75.2 Bicipital tendinitis	0.065	0.934	0.000
M45-M49 Spondylopathies	0.065	0.935	0.000
I67 Other cerebrovascular diseases	0.065	0.935	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.065	0.935	0.000
H40-H42 Glaucoma	0.065	0.935	0.000
C44.3 Skin of other and unspecified parts of face	0.064	0.935	0.000
I44.0 Atrioventricular block, first degree	0.064	0.936	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.064	0.936	0.000
F41 Other anxiety disorders	0.064	0.936	0.000
I21 Acute myocardial infarction	0.064	0.936	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.063	0.937	0.000
D00-D09 In situ neoplasms	0.063	0.937	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.063	0.937	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.063	0.937	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.063	0.937	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.063	0.937	0.000
C60-C63 Malignant neoplasms of male genital organs	0.063	0.937	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.063	0.937	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.063	0.937	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.063	0.937	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.063	0.937	0.000
O60-O75 Complications of labour and delivery	0.063	0.937	0.000
I52 Other heart disorders in diseases classified elsewhere	0.063	0.937	0.000
I48 Atrial fibrillation and flutter	0.063	0.937	0.000
I46 Cardiac arrest	0.063	0.937	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.063	0.937	0.000
I42 Cardiomyopathy	0.063	0.937	0.000
I41 Myocarditis in diseases classified elsewhere	0.063	0.937	0.000
I40 Acute myocarditis	0.063	0.937	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.063	0.937	0.000
I37 Pulmonary valve disorders	0.063	0.937	0.000
I36 Nonrheumatic tricuspid valve disorders	0.063	0.937	0.000
I35 Nonrheumatic aortic valve disorders	0.063	0.937	0.000
I33 Acute and subacute endocarditis	0.063	0.937	0.000
I32 Pericarditis in diseases classified elsewhere	0.063	0.937	0.000
I31 Other diseases of pericardium	0.063	0.937	0.000
I30 Acute pericarditis	0.063	0.937	0.000
I38 Endocarditis, valve unspecified	0.063	0.937	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.063	0.937	0.000
M23.3 Other meniscus derangements	0.063	0.937	0.000
C44.5 Skin of trunk	0.063	0.937	0.000
I50 Heart failure	0.063	0.937	0.000
C51-C58 Malignant neoplasms of female genital organs	0.063	0.937	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.063	0.937	0.000
O85-O92 Complications predominantly related to the puerperium	0.062	0.937	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.062	0.937	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.062	0.938	0.000
F99-F99 Unspecified mental disorder	0.062	0.938	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.062	0.938	0.000
F80-F89 Disorders of psychological development	0.062	0.938	0.000
F70-F79 Mental retardation	0.062	0.938	0.000
F60-F69 Disorders of adult personality and behaviour	0.062	0.938	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.062	0.938	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.062	0.938	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.062	0.938	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.062	0.938	0.000
E86 Volume depletion	0.062	0.938	0.000
I49.0 Ventricular fibrillation and flutter	0.062	0.938	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.062	0.938	0.000
O16 Unspecified maternal hypertension	0.061	0.938	0.000
M14 Arthropathies in other diseases classified elsewhere	0.061	0.939	0.000
M12 Other specific arthropathies	0.061	0.939	0.000
M11 Other crystal arthropathies	0.061	0.939	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.061	0.939	0.000
M08 Juvenile arthritis	0.061	0.939	0.000
M07 Psoriatic and enteropathic arthropathies	0.061	0.939	0.000
M05 Seropositive rheumatoid arthritis	0.061	0.939	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.061	0.939	0.000
A00-A09 Intestinal infectious diseases	0.061	0.939	0.000
I47 Paroxysmal tachycardia	0.061	0.939	0.000
H26 Other cataract	0.061	0.939	0.000
C18 Malignant neoplasm of colon	0.060	0.939	0.000
H00 Hordeolum and chalazion	0.060	0.939	0.000
M10 Gout	0.060	0.939	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.060	0.940	0.000
F32 Depressive episode	0.060	0.940	0.000
H36 Retinal disorders in diseases classified elsewhere	0.060	0.940	0.000
H34 Retinal vascular occlusions	0.060	0.940	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.060	0.940	0.000
H31 Other disorders of choroid	0.060	0.940	0.000
H30 Chorioretinal inflammation	0.060	0.940	0.000
H25 Senile cataract	0.060	0.940	0.000
H04 Disorders of lachrymal system	0.059	0.940	0.000
H53 Visual disturbances	0.059	0.941	0.000
I25 Chronic ischaemic heart disease	0.059	0.941	0.000
M50-M54 Other dorsopathies	0.059	0.941	0.000
H02 Other disorders of eyelid	0.059	0.941	0.000
Chapter VI Diseases of the nervous system	0.059	0.941	0.000
M20 Acquired deformities of fingers and toes	0.059	0.941	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.059	0.941	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.058	0.942	0.000
M35 Other systemic involvement of connective tissue	0.058	0.942	0.000
M34 Systemic sclerosis	0.058	0.942	0.000
M33 Dermatopolymyositis	0.058	0.942	0.000
M32 Systemic lupus erythematosus	0.058	0.942	0.000
M31 Other necrotising vasculopathies	0.058	0.942	0.000
M30 Polyarteritis nodosa and related conditions	0.058	0.942	0.000
M24 Other specific joint derangements	0.058	0.942	0.000
M22 Disorders of patella	0.058	0.942	0.000
M21 Other acquired deformities of limbs	0.058	0.942	0.000
I34 Nonrheumatic mitral valve disorders	0.058	0.942	0.000
B95-B98 Bacterial, viral and other infectious agents	0.058	0.942	0.000
E50-E64 Other nutritional deficiencies	0.058	0.942	0.000
E40-E46 Malnutrition	0.058	0.942	0.000
E20-E35 Disorders of other endocrine glands	0.058	0.942	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.058	0.942	0.000
I49.9 Cardiac arrhythmia, unspecified	0.058	0.942	0.000
I95 Hypotension	0.058	0.942	0.000
O03 Spontaneous abortion	0.058	0.942	0.000
B35-B49 Mycoses	0.058	0.942	0.000
I44.6 Other and unspecified fascicular block	0.058	0.942	0.000
I44.5 Left posterior fascicular block	0.058	0.942	0.000
I44.4 Left anterior fascicular block	0.058	0.942	0.000
I44.3 Other and unspecified atrioventricular block	0.058	0.942	0.000
I44.2 Atrioventricular block, complete	0.058	0.942	0.000
I44.1 Atrioventricular block, second degree	0.058	0.942	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.058	0.942	0.000
C43 Malignant melanoma of skin	0.057	0.942	0.000
M81 Osteoporosis without pathological fracture	0.057	0.943	0.000
D17 Benign lipomatous neoplasm	0.057	0.943	0.000
H90-H95 Other disorders of ear	0.057	0.943	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.057	0.943	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.057	0.943	0.000
S80-S89 Injuries to the knee and lower leg	0.056	0.943	0.000
I63 Cerebral infarction	0.056	0.943	0.000
M15-M19 Arthrosis	0.056	0.944	0.000
I45.1 Other and unspecified right bundle-branch block	0.056	0.944	0.000
S50-S59 Injuries to the elbow and forearm	0.056	0.944	0.000
C44.4 Skin of scalp and neck	0.056	0.944	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.056	0.944	0.000
T79-T79 Certain early complications of trauma	0.056	0.944	0.000
T66-T78 Other and unspecified effects of external causes	0.056	0.944	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.056	0.944	0.000
T33-T35 Frostbite	0.056	0.944	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.056	0.944	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.056	0.944	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.056	0.944	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.056	0.944	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.056	0.944	0.000
T00-T07 Injuries involving multiple body regions	0.056	0.944	0.000
S90-S99 Injuries to the ankle and foot	0.056	0.944	0.000
S70-S79 Injuries to the hip and thigh	0.056	0.944	0.000
S40-S49 Injuries to the shoulder and upper arm	0.056	0.944	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.056	0.944	0.000
S20-S29 Injuries to the thorax	0.056	0.944	0.000
S10-S19 Injuries to the neck	0.056	0.944	0.000
I71 Aortic aneurysm and dissection	0.056	0.944	0.000
D27 Benign neoplasm of ovary	0.056	0.944	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.056	0.944	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.056	0.944	0.000
C25 Malignant neoplasm of pancreas	0.056	0.944	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.056	0.944	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.056	0.944	0.000
C21 Malignant neoplasm of anus and anal canal	0.056	0.944	0.000
C17 Malignant neoplasm of small intestine	0.056	0.944	0.000
C16 Malignant neoplasm of stomach	0.056	0.944	0.000
C15 Malignant neoplasm of oesophagus	0.056	0.944	0.000
C23 Malignant neoplasm of gallbladder	0.056	0.944	0.000
C20 Malignant neoplasm of rectum	0.056	0.944	0.000
D18 Haemangioma and lymphangioma, any site	0.056	0.944	0.000
S60-S69 Injuries to the wrist and hand	0.056	0.944	0.000
C44.7 Skin of lower limb, including hip	0.056	0.944	0.000
B99-B99 Other infectious diseases	0.056	0.944	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.056	0.944	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.056	0.944	0.000
B65-B83 Helminthiases	0.056	0.944	0.000
B50-B64 Protozoal diseases	0.056	0.944	0.000
B25-B34 Other viral diseases	0.056	0.944	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.056	0.944	0.000
B15-B19 Viral hepatitis	0.056	0.944	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.056	0.944	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.056	0.944	0.000
A80-A89 Viral infections of the central nervous system	0.056	0.944	0.000
A75-A79 Rickettsioses	0.056	0.944	0.000
A70-A74 Other diseases caused by chlamydiae	0.056	0.944	0.000
A65-A69 Other spirochaetal diseases	0.056	0.944	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.056	0.944	0.000
A20-A28 Certain zoonotic bacterial diseases	0.056	0.944	0.000
A15-A19 Tuberculosis	0.056	0.944	0.000
M06.9 Rheumatoid arthritis, unspecified	0.056	0.944	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.055	0.944	0.000
H05 Disorders of orbit	0.055	0.944	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.055	0.944	0.000
H01 Other inflammation of eyelid	0.055	0.944	0.000
I69 Sequelae of cerebrovascular disease	0.055	0.944	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.055	0.944	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.055	0.944	0.000
I62 Other nontraumatic intracranial haemorrhage	0.055	0.944	0.000
I61 Intracerebral haemorrhage	0.055	0.944	0.000
I60 Subarachnoid haemorrhage	0.055	0.944	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.055	0.944	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.055	0.944	0.000
E10-E14 Diabetes mellitus	0.055	0.944	0.000
S00-S09 Injuries to the head	0.055	0.945	0.000
A30-A49 Other bacterial diseases	0.055	0.945	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.055	0.945	0.000
H27 Other disorders of lens	0.055	0.945	0.000
H33.0 Retinal detachment with retinal break	0.055	0.945	0.000
M25 Other joint disorders, not elsewhere classified	0.054	0.945	0.000
F41.9 Anxiety disorder, unspecified	0.055	0.945	0.000
E65-E68 Obesity and other hyperalimentation	0.054	0.946	0.000
H52 Disorders of refraction and accommodation	0.054	0.946	0.000
M79.7 Fibromyalgia	0.054	0.946	0.000
H35.3 Degeneration of macula and posterior pole	0.054	0.946	0.000
E00-E07 Disorders of thyroid gland	0.054	0.946	0.000
E88 Other metabolic disorders	0.053	0.946	0.000
E85 Amyloidosis	0.053	0.946	0.000
E84 Cystic fibrosis	0.053	0.946	0.000
E83 Disorders of mineral metabolism	0.053	0.946	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.053	0.946	0.000
E79 Disorders of purine and pyrimidine metabolism	0.053	0.946	0.000
E77 Disorders of glycoprotein metabolism	0.053	0.946	0.000
E76 Disorders of glycosaminoglycan metabolism	0.053	0.946	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.053	0.946	0.000
E74 Other disorders of carbohydrate metabolism	0.053	0.946	0.000
E73 Lactose intolerance	0.053	0.946	0.000
E72 Other disorders of amino-acid metabolism	0.053	0.946	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.053	0.946	0.000
E70 Disorders of aromatic amino-acid metabolism	0.053	0.946	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.053	0.946	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.053	0.946	0.000
C44.8 Overlapping lesion of skin	0.053	0.946	0.000
C44.6 Skin of upper limb, including shoulder	0.053	0.946	0.000
C44.2 Skin of ear and external auricular canal	0.053	0.946	0.000
C44.1 Skin of eyelid, including canthus	0.053	0.946	0.000
C44.0 Skin of lip	0.053	0.946	0.000
I49.8 Other specified cardiac arrhythmias	0.053	0.946	0.000
I49.5 Sick sinus syndrome	0.053	0.946	0.000
I49.4 Other and unspecified premature depolarisation	0.053	0.946	0.000
I49.3 Ventricular premature depolarisation	0.053	0.946	0.000
I49.2 Junctional premature depolarisation	0.053	0.946	0.000
I49.1 Atrial premature depolarisation	0.053	0.946	0.000
I24 Other acute ischaemic heart diseases	0.053	0.947	0.000
I23 Certain current complications following acute myocardial infarction	0.053	0.947	0.000
I22 Subsequent myocardial infarction	0.053	0.947	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.053	0.947	0.000
M13.8 Other specified arthritis	0.053	0.947	0.000
M13.1 Monoarthritis, not elsewhere classified	0.053	0.947	0.000
M13.0 Polyarthritis, unspecified	0.053	0.947	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.053	0.947	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.053	0.947	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.053	0.947	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.053	0.947	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.053	0.947	0.000
Y35-Y36 Legal intervention and operations of war	0.053	0.947	0.000
Y10-Y34 Event of undetermined intent	0.053	0.947	0.000
Y00-Y09 Assault	0.053	0.947	0.000
X85-X99 Assault	0.053	0.947	0.000
X60-X84 Intentional self-harm	0.053	0.947	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.053	0.947	0.000
X50-X57 Overexertion, travel and privation	0.053	0.947	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.053	0.947	0.000
X30-X39 Exposure to forces of nature	0.053	0.947	0.000
X20-X29 Contact with venomous animals and plants	0.053	0.947	0.000
X10-X19 Contact with heat and hot substances	0.053	0.947	0.000
X00-X09 Exposure to smoke, fire and flames	0.053	0.947	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.053	0.947	0.000
W75-W84 Other accidental threats to breathing	0.053	0.947	0.000
W65-W74 Accidental drowning and submersion	0.053	0.947	0.000
W50-W64 Exposure to animate mechanical forces	0.053	0.947	0.000
W20-W49 Exposure to inanimate mechanical forces	0.053	0.947	0.000
V98-V99 Other and unspecified transport accidents	0.053	0.947	0.000
V95-V97 Air and space transport accidents	0.053	0.947	0.000
V90-V94 Water transport accidents	0.053	0.947	0.000
V80-V89 Other land transport accidents	0.053	0.947	0.000
V70-V79 Bus occupant injured in transport accident	0.053	0.947	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.053	0.947	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.053	0.947	0.000
V40-V49 Car occupant injured in transport accident	0.053	0.947	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.053	0.947	0.000
V20-V29 Motorcycle rider injured in transport accident	0.053	0.947	0.000
V10-V19 Pedal cyclist injured in transport accident	0.053	0.947	0.000
V01-V09 Pedestrian injured in transport accident	0.053	0.947	0.000
I67.8 Other specified cerebrovascular diseases	0.053	0.947	0.000
H33.5 Other retinal detachments	0.053	0.947	0.000
H33.4 Traction detachment of retina	0.053	0.947	0.000
H33.2 Serous retinal detachment	0.053	0.947	0.000
H33.1 Retinoschisis and retinal cysts	0.053	0.947	0.000
H54 Blindness and low vision	0.053	0.947	0.000
F48 Other neurotic disorders	0.053	0.947	0.000
F45 Somatoform disorders	0.053	0.947	0.000
F44 Dissociative [conversion] disorders	0.053	0.947	0.000
F43 Reaction to severe stress, and adjustment disorders	0.053	0.947	0.000
F42 Obsessive-compulsive disorder	0.053	0.947	0.000
F40 Phobic anxiety disorders	0.053	0.947	0.000
M85 Other disorders of bone density and structure	0.053	0.947	0.000
M84 Disorders of continuity of bone	0.053	0.947	0.000
M83 Adult osteomalacia	0.053	0.947	0.000
M82 Osteoporosis in diseases classified elsewhere	0.053	0.947	0.000
M80 Osteoporosis with pathological fracture	0.053	0.947	0.000
H80-H83 Diseases of inner ear	0.053	0.947	0.000
H65-H75 Diseases of middle ear and mastoid	0.053	0.947	0.000
H60-H62 Diseases of external ear	0.053	0.947	0.000
I67.9 Cerebrovascular disease, unspecified	0.053	0.947	0.000
F32.9 Depressive episode, unspecified	0.052	0.948	0.000
C50-C50 Malignant neoplasm of breast	0.051	0.948	0.001
I51.8 Other ill-defined heart diseases	0.052	0.948	0.000
M23.9 Internal derangement of knee, unspecified	0.052	0.948	0.000
M23.8 Other internal derangements of knee	0.052	0.948	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.052	0.948	0.000
M23.5 Chronic instability of knee	0.052	0.948	0.000
M23.4 Loose body in knee	0.052	0.948	0.000
M23.1 Discoid meniscus (congenital)	0.052	0.948	0.000
M23.0 Cystic meniscus	0.052	0.948	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.052	0.948	0.000
O15 Eclampsia	0.052	0.948	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.052	0.948	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.052	0.948	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.052	0.948	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.052	0.948	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.052	0.948	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.052	0.948	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.052	0.948	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.052	0.948	0.000
I99 Other and unspecified disorders of circulatory system	0.052	0.948	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.052	0.948	0.000
F38 Other mood [affective] disorders	0.051	0.949	0.000
F34 Persistent mood [affective] disorders	0.051	0.949	0.000
F33 Recurrent depressive disorder	0.051	0.949	0.000
F31 Bipolar affective disorder	0.051	0.949	0.000
F30 Manic episode	0.051	0.949	0.000
F39 Unspecified mood [affective] disorder	0.051	0.949	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.051	0.949	0.000
O80 Single spontaneous delivery	0.051	0.949	0.000
I51.7 Cardiomegaly	0.051	0.949	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.051	0.949	0.000
H51 Other disorders of binocular movement	0.051	0.949	0.000
H50 Other strabismus	0.051	0.949	0.000
H49 Paralytic strabismus	0.051	0.949	0.000
M65 Synovitis and tenosynovitis	0.050	0.949	0.000
I21.4 Acute subendocardial myocardial infarction	0.050	0.949	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.050	0.949	0.000
O07 Failed attempted abortion	0.050	0.949	0.000
O06 Unspecified abortion	0.050	0.949	0.000
O05 Other abortion	0.050	0.949	0.000
O04 Medical abortion	0.050	0.949	0.000
O02 Other abnormal products of conception	0.050	0.949	0.000
O01 Hydatidiform mole	0.050	0.949	0.000
O00 Ectopic pregnancy	0.050	0.949	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.050	0.950	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.050	0.950	0.000
I78 Diseases of capillaries	0.050	0.950	0.000
I77 Other disorders of arteries and arterioles	0.050	0.950	0.000
I74 Arterial embolism and thrombosis	0.050	0.950	0.000
I72 Other aneurysm	0.050	0.950	0.000
I70 Atherosclerosis	0.050	0.950	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.050	0.950	0.000
M67 Other disorders of synovium and tendon	0.050	0.950	0.000
M66 Spontaneous rupture of synovium and tendon	0.050	0.950	0.000
I45.9 Conduction disorder, unspecified	0.050	0.950	0.000
I45.8 Other specified conduction disorders	0.050	0.950	0.000
I45.6 Preexcitation syndrome	0.050	0.950	0.000
I45.5 Other specified heart block	0.050	0.950	0.000
I45.4 Nonspecific intraventricular block	0.050	0.950	0.000
I45.3 Trifascicular block	0.050	0.950	0.000
I45.2 Bifascicular block	0.050	0.950	0.000
I45.0 Right fascicular block	0.050	0.950	0.000
Y83.6 Removal of other organ (partial) (total)	0.050	0.950	0.000
I25.2 Old myocardial infarction	0.050	0.950	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.050	0.950	0.000
P90-P96 Other disorders originating in the perinatal period	0.049	0.950	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.049	0.950	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.049	0.950	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.049	0.950	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.049	0.950	0.000
P35-P39 Infections specific to the perinatal period	0.049	0.950	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.049	0.950	0.000
P10-P15 Birth trauma	0.049	0.950	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.049	0.950	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.049	0.950	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.049	0.950	0.000
Q80-Q89 Other congenital malformations	0.049	0.950	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.049	0.950	0.000
Q60-Q64 Congenital malformations of the urinary system	0.049	0.950	0.000
Q50-Q56 Congenital malformations of genital organs	0.049	0.950	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.049	0.950	0.000
Q35-Q37 Cleft lip and cleft palate	0.049	0.950	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.049	0.950	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.049	0.950	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.049	0.950	0.000
Q00-Q07 Congenital malformations of the nervous system	0.049	0.950	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.049	0.950	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.049	0.950	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.049	0.950	0.000
M02 Reactive arthropathies	0.049	0.950	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.049	0.950	0.000
M00 Pyogenic arthritis	0.049	0.950	0.000
M43 Other deforming dorsopathies	0.049	0.950	0.000
M42 Spinal osteochondrosis	0.049	0.950	0.000
M41 Scoliosis	0.049	0.950	0.000
M40 Kyphosis and lordosis	0.049	0.950	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.049	0.950	0.000
M62 Other disorders of muscle	0.049	0.950	0.000
M61 Calcification and ossification of muscle	0.049	0.950	0.000
M60 Myositis	0.049	0.950	0.000
M90 Osteopathies in diseases classified elsewhere	0.049	0.950	0.000
M89 Other disorders of bone	0.049	0.950	0.000
M88 Paget's disease of bone [osteitis deformans]	0.049	0.950	0.000
M87 Osteonecrosis	0.049	0.950	0.000
M86 Osteomyelitis	0.049	0.950	0.000
M94 Other disorders of cartilage	0.049	0.950	0.000
M93 Other osteochondropathies	0.049	0.950	0.000
M92 Other juvenile osteochondrosis	0.049	0.950	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.049	0.950	0.000
M99 Biomechanical lesions, not elsewhere classified	0.049	0.950	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.049	0.950	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.049	0.950	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.049	0.950	0.000
H25.0 Senile incipient cataract	0.049	0.950	0.000
H53.0 Amblyopia ex anopsia	0.049	0.951	0.000
H26.9 Cataract, unspecified	0.049	0.951	0.000
D50-D53 Nutritional anaemias	0.049	0.951	0.000
H02.3 Blepharochalasis	0.049	0.951	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.049	0.951	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.049	0.951	0.000
O48 Prolonged pregnancy	0.049	0.951	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations