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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76594396
log Bayes Factor = 11.0301
Chromosome 8   position 5,443,735  (GRCh37) Explore rs76594396 on Ensembl!
Variant rs76594396 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
S00-S09 Injuries to the head
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
S60-S69 Injuries to the wrist and hand
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.990 0.010 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.986 0.014 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
S61 Open wound of wrist and hand
0.980 0.020 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.976 0.024 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
S61.0 Open wound of finger(s) without damage to nail
0.972 0.028 0.000
S09 Other and unspecified injuries of head
0.969 0.031 0.000
Chapter VIII Diseases of the ear and mastoid process
0.967 0.033 0.000
I71 Aortic aneurysm and dissection
0.963 0.037 0.000
M25 Other joint disorders, not elsewhere classified
0.960 0.040 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.958 0.042 0.000
S05 Injury of eye and orbit
0.958 0.042 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.953 0.047 0.000
I60-I69 Cerebrovascular diseases
0.953 0.047 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.951 0.049 0.000
S09.9 Unspecified injury of head
0.948 0.052 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.944 0.056 0.000
S80-S89 Injuries to the knee and lower leg
0.940 0.060 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.936 0.064 0.000
S70-S79 Injuries to the hip and thigh
0.931 0.069 0.000
S20-S29 Injuries to the thorax
0.929 0.071 0.000
I70 Atherosclerosis
0.921 0.079 0.000
M80-M85 Disorders of bone density and structure
0.920 0.080 0.000
S50-S59 Injuries to the elbow and forearm
0.917 0.083 0.000
M50-M54 Other dorsopathies
0.913 0.087 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.913 0.087 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.906 0.094 0.000
I63 Cerebral infarction
0.899 0.101 0.000
M25.8 Other specified joint disorders
0.898 0.102 0.000
W00-W19 Falls
0.898 0.102 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.894 0.106 0.000
W50-W64 Exposure to animate mechanical forces
0.894 0.106 0.000
S02 Fracture of skull and facial bones
0.893 0.107 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.889 0.111 0.000
M65-M68 Disorders of synovium and tendon
0.887 0.113 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.886 0.114 0.000
H65-H75 Diseases of middle ear and mastoid
0.883 0.117 0.000
I26 Pulmonary embolism
0.881 0.119 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.880 0.120 0.000
I62 Other nontraumatic intracranial haemorrhage
0.878 0.122 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.878 0.122 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.876 0.124 0.000
I27 Other pulmonary heart diseases
0.875 0.125 0.000
S72 Fracture of femur
0.875 0.125 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.872 0.128 0.000
S69 Other and unspecified injuries of wrist and hand
0.872 0.128 0.000
S27 Injury of other and unspecified intrathoracic organs
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.871 0.129 0.000
M54 Dorsalgia
0.868 0.132 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.866 0.134 0.000
M22 Disorders of patella
0.865 0.135 0.000
M35 Other systemic involvement of connective tissue
0.865 0.135 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.864 0.136 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.860 0.140 0.000
M24 Other specific joint derangements
0.858 0.142 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.857 0.143 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.856 0.144 0.000
S60 Superficial injury of wrist and hand
0.856 0.144 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.856 0.144 0.000
M84 Disorders of continuity of bone
0.855 0.145 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.853 0.147 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.852 0.148 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
T79-T79 Certain early complications of trauma
0.846 0.154 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.845 0.155 0.000
S61.8 Open wound of other parts of wrist and hand
0.844 0.156 0.000
S06 Intracranial injury
0.842 0.158 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.839 0.161 0.000
Q50-Q56 Congenital malformations of genital organs
0.839 0.161 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.839 0.161 0.000
I27.0 Primary pulmonary hypertension
0.836 0.164 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.835 0.165 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.829 0.171 0.000
O80-O84 Delivery
0.827 0.173 0.000
Y00-Y09 Assault
0.827 0.173 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.825 0.175 0.000
S52 Fracture of forearm
0.825 0.175 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.823 0.177 0.000
H73 Other disorders of tympanic membrane
0.822 0.178 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.821 0.179 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.820 0.180 0.000
M34 Systemic sclerosis
0.819 0.181 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.819 0.181 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.817 0.183 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.817 0.183 0.000
M25.9 Joint disorder, unspecified
0.815 0.185 0.000
H80-H83 Diseases of inner ear
0.814 0.186 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.814 0.186 0.000
M54.4 Lumbago with sciatica
0.813 0.187 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.813 0.187 0.000
Q80-Q89 Other congenital malformations
0.811 0.189 0.000
T86 Failure and rejection of transplanted organs and tissues
0.810 0.190 0.000
S72.4 Fracture of lower end of femur
0.810 0.190 0.000
X60-X84 Intentional self-harm
0.807 0.193 0.000
M54.3 Sciatica
0.807 0.193 0.000
M35.0 Sicca syndrome [Sjogren]
0.804 0.196 0.000
S27.0 Traumatic pneumothorax
0.804 0.196 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.804 0.196 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.803 0.197 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.802 0.198 0.000
Y86 Sequelae of other accidents
0.802 0.198 0.000
V40-V49 Car occupant injured in transport accident
0.799 0.201 0.000
I77 Other disorders of arteries and arterioles
0.798 0.202 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.797 0.203 0.000
I74 Arterial embolism and thrombosis
0.796 0.204 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.795 0.205 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.795 0.205 0.000
Q60-Q64 Congenital malformations of the urinary system
0.794 0.206 0.000
S05.8 Other injuries of eye and orbit
0.793 0.207 0.000
T82.3 Mechanical complication of other vascular grafts
0.792 0.207 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.792 0.208 0.000
W19 Unspecified fall
0.791 0.209 0.000
T43.2 Other and unspecified antidepressants
0.791 0.209 0.000
M67 Other disorders of synovium and tendon
0.786 0.214 0.000
H74 Other disorders of middle ear and mastoid
0.783 0.217 0.000
M60-M63 Disorders of muscles
0.783 0.217 0.000
T00-T07 Injuries involving multiple body regions
0.783 0.217 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.782 0.218 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.782 0.218 0.000
Y40 Systemic antibiotics
0.780 0.220 0.000
H90-H95 Other disorders of ear
0.779 0.221 0.000
S68 Traumatic amputation of wrist and hand
0.778 0.222 0.000
H73.8 Other specified disorders of tympanic membrane
0.778 0.222 0.000
T42.4 Benzodiazepines
0.777 0.223 0.000
M25.4 Effusion of joint
0.776 0.224 0.000
S62 Fracture at wrist and hand level
0.775 0.225 0.000
S80 Superficial injury of lower leg
0.774 0.226 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
I61 Intracerebral haemorrhage
0.771 0.229 0.000
V98-V99 Other and unspecified transport accidents
0.771 0.229 0.000
M33 Dermatopolymyositis
0.771 0.229 0.000
W19.2 School, other institution and public administrative area
0.768 0.232 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.768 0.232 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
Y48 Anaesthetics and therapeutic gases
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.763 0.237 0.000
S72.40 Fracture of lower end of femur (closed)
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.762 0.237 0.000
Chapter XXII Codes for special purposes
0.762 0.237 0.000
O21 Excessive vomiting in pregnancy
0.762 0.238 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.762 0.238 0.000
M80 Osteoporosis with pathological fracture
0.762 0.238 0.000
M25.5 Pain in joint
0.761 0.239 0.000
M84.0 Malunion of fracture
0.761 0.239 0.000
T42.1 Iminostilbenes
0.760 0.240 0.000
I78 Diseases of capillaries
0.760 0.240 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.756 0.244 0.000
M54.39 Sciatica (Site unspecified)
0.756 0.244 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.755 0.245 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.754 0.246 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.752 0.248 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.752 0.248 0.000
Q00-Q07 Congenital malformations of the nervous system
0.752 0.248 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.751 0.249 0.000
W55 Bitten or struck by other mammals
0.751 0.249 0.000
S82 Fracture of lower leg, including ankle
0.751 0.249 0.000
T39.1 4-Aminophenol derivatives
0.750 0.250 0.000
S69.9 Unspecified injury of wrist and hand
0.750 0.250 0.000
O23 Infections of genito-urinary tract in pregnancy
0.750 0.250 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.749 0.251 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.749 0.251 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.747 0.253 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.747 0.253 0.000
I69 Sequelae of cerebrovascular disease
0.746 0.254 0.000
S02.4 Fracture of malar and maxillary bones
0.746 0.254 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.745 0.255 0.000
S10-S19 Injuries to the neck
0.745 0.255 0.000
H83 Other diseases of inner ear
0.745 0.255 0.000
I73 Other peripheral vascular diseases
0.745 0.255 0.000
S29 Other and unspecified injuries of thorax
0.744 0.256 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.744 0.256 0.000
W07 Fall involving chair
0.740 0.260 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.740 0.260 0.000
M21 Other acquired deformities of limbs
0.740 0.260 0.000
V20-V29 Motorcycle rider injured in transport accident
0.740 0.260 0.000
Q23 Congenital malformations of aortic and mitral valves
0.740 0.260 0.000
S72.3 Fracture of shaft of femur
0.740 0.260 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.739 0.261 0.000
Y45.5 4-Aminophenol derivatives
0.738 0.261 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.737 0.263 0.000
M50 Cervical disk disorders
0.737 0.263 0.000
M22.4 Chondromalacia patellae
0.737 0.263 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.736 0.264 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.736 0.264 0.000
S63.6 Sprain and strain of finger(s)
0.735 0.265 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.734 0.266 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.734 0.266 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.734 0.266 0.000
Q82 Other congenital malformations of skin
0.732 0.268 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.729 0.271 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.728 0.272 0.000
S02.2 Fracture of nasal bones
0.727 0.273 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.726 0.274 0.000
O20 Haemorrhage in early pregnancy
0.724 0.276 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.723 0.277 0.000
Y54.3 Benzothiadiazine derivatives
0.722 0.278 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.721 0.279 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.721 0.279 0.000
T93 Sequelae of injuries of lower limb
0.719 0.281 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.716 0.283 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.284 0.000
T36 Poisoning by systemic antibiotics
0.715 0.284 0.000
S02.6 Fracture of mandible
0.716 0.284 0.000
M22.2 Patellofemoral disorders
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.715 0.285 0.000
S81 Open wound of lower leg
0.714 0.286 0.000
S65 Injury of blood vessels at wrist and hand level
0.714 0.286 0.000
M24.2 Disorder of ligament
0.714 0.286 0.000
T40.2 Other opioids
0.713 0.287 0.000
I77.1 Stricture of artery
0.712 0.288 0.000
M34.1 CR(E)ST syndrome
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.710 0.290 0.000
T90 Sequelae of injuries of head
0.710 0.290 0.000
T39.0 Salicylates
0.710 0.290 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.710 0.290 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.710 0.290 0.000
M67.8 Other specified disorders of synovium and tendon
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.293 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.293 0.000
S51 Open wound of forearm
0.706 0.294 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
M32 Systemic lupus erythematosus
0.704 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.296 0.000
H92 Otalgia and effusion of ear
0.704 0.296 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.704 0.296 0.000
Y49.5 Other antipsychotics and neuroleptics
0.704 0.296 0.000
M85 Other disorders of bone density and structure
0.704 0.296 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.703 0.297 0.000
Q43 Other congenital malformations of intestine
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
V10-V19 Pedal cyclist injured in transport accident
0.701 0.299 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
S50 Superficial injury of forearm
0.700 0.300 0.000
S09.8 Other specified injuries of head
0.700 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
Q24 Other congenital malformations of heart
0.697 0.302 0.000
T58 Toxic effect of carbon monoxide
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
M66 Spontaneous rupture of synovium and tendon
0.695 0.305 0.000
H83.0 Labyrinthitis
0.695 0.305 0.000
S09.7 Multiple injuries of head
0.694 0.305 0.000
S09.2 Traumatic rupture of ear drum
0.694 0.305 0.000
S09.1 Injury of muscle and tendon of head
0.694 0.305 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.694 0.305 0.000
Chapter V Mental and behavioural disorders
0.694 0.306 0.000
O82 Single delivery by Caesarean section
0.694 0.306 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.694 0.306 0.000
M35.2 Behcet's disease
0.693 0.307 0.000
M84.03 Malunion of fracture (Forearm)
0.693 0.307 0.000
S79 Other and unspecified injuries of hip and thigh
0.693 0.307 0.000
S69.8 Other specified injuries of wrist and hand
0.693 0.307 0.000
Y85 Sequelae of transport accidents
0.692 0.308 0.000
S06.8 Other intracranial injuries
0.692 0.308 0.000
S00 Superficial injury of head
0.692 0.308 0.000
M24.5 Contracture of joint
0.691 0.309 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.690 0.310 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.690 0.310 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.690 0.310 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.690 0.310 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.690 0.310 0.000
M25.2 Flail joint
0.688 0.312 0.000
M25.1 Fistula of joint
0.688 0.312 0.000
M25.0 Haemarthrosis
0.688 0.312 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.688 0.312 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.688 0.312 0.000
Y49.2 Other and unspecified antidepressants
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.688 0.312 0.000
I69.3 Sequelae of cerebral infarction
0.688 0.312 0.000
S67 Crushing injury of wrist and hand
0.687 0.313 0.000
I28 Other diseases of pulmonary vessels
0.687 0.313 0.000
S05.9 Injury of eye and orbit, part unspecified
0.687 0.313 0.000
S05.7 Avulsion of eye
0.687 0.313 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.687 0.313 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.687 0.313 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.687 0.313 0.000
S05.1 Contusion of eyeball and orbital tissues
0.687 0.313 0.000
S86 Injury of muscle and tendon at lower leg level
0.687 0.313 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.686 0.314 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.683 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.683 0.317 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.682 0.318 0.000
S89 Other and unspecified injuries of lower leg
0.682 0.318 0.000
M25.59 Pain in joint (Site unspecified)
0.681 0.319 0.000
Y45.1 Salicylates
0.681 0.319 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.681 0.319 0.000
S62.2 Fracture of first metacarpal bone
0.680 0.319 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.680 0.320 0.000
M00-M03 Infectious arthropathies
0.680 0.320 0.000
Q54 Hypospadias
0.680 0.320 0.000
Q21 Congenital malformations of cardiac septa
0.678 0.322 0.000
T43.9 Psychotropic drug, unspecified
0.677 0.323 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
T43.6 Psychostimulants with abuse potential
0.677 0.323 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.677 0.323 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.676 0.323 0.000
Y89 Sequelae of other external causes
0.675 0.325 0.000
M22.3 Other derangements of patella
0.675 0.325 0.000
W15 Fall from cliff
0.674 0.326 0.000
M50.0 Cervical disk disorder with myelopathy
0.674 0.326 0.000
S88 Traumatic amputation of lower leg
0.674 0.326 0.000
S87 Crushing injury of lower leg
0.674 0.326 0.000
S85 Injury of blood vessels at lower leg level
0.674 0.326 0.000
S84 Injury of nerves at lower leg level
0.674 0.326 0.000
S27.1 Traumatic haemothorax
0.674 0.326 0.000
M35.1 Other overlap syndromes
0.673 0.327 0.000
S56 Injury of muscle and tendon at forearm level
0.672 0.328 0.000
S70 Superficial injury of hip and thigh
0.672 0.328 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.671 0.329 0.000
Q55 Other congenital malformations of male genital organs
0.671 0.329 0.000
S02.8 Fractures of other skull and facial bones
0.670 0.330 0.000
S52.1 Fracture of upper end of radius
0.670 0.330 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.670 0.330 0.000
S72.2 Subtrochanteric fracture
0.669 0.331 0.000
T56 Toxic effect of metals
0.669 0.331 0.000
Y57 Other and unspecified drugs and medicaments
0.669 0.331 0.000
I77.8 Other specified disorders of arteries and arterioles
0.669 0.331 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.668 0.332 0.000
I63.8 Other cerebral infarction
0.668 0.332 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.668 0.332 0.000
S78 Traumatic amputation of hip and thigh
0.667 0.333 0.000
S77 Crushing injury of hip and thigh
0.667 0.333 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.667 0.333 0.000
S75 Injury of blood vessels at hip and thigh level
0.667 0.333 0.000
S74 Injury of nerves at hip and thigh level
0.667 0.333 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.667 0.333 0.000
S71 Open wound of hip and thigh
0.667 0.333 0.000
S02.7 Multiple fractures involving skull and facial bones
0.667 0.333 0.000
S60.0 Contusion of finger(s) without damage to nail
0.666 0.334 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.666 0.334 0.000
S26 Injury of heart
0.666 0.334 0.000
S25 Injury of blood vessels of thorax
0.666 0.334 0.000
S24 Injury of nerves and spinal cord at thorax level
0.666 0.334 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.666 0.334 0.000
S21 Open wound of thorax
0.666 0.334 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.666 0.334 0.000
H92.1 Otorrhoea
0.665 0.335 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.665 0.335 0.000
S42 Fracture of shoulder and upper arm
0.665 0.335 0.000
H69 Other disorders of Eustachian tube
0.664 0.335 0.000
Y04 Assault by bodily force
0.664 0.336 0.000
O80 Single spontaneous delivery
0.663 0.337 0.000
S27.3 Other injuries of lung
0.663 0.337 0.000
S52.7 Multiple fractures of forearm
0.663 0.337 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.662 0.338 0.000
Y45.8 Other analgesics and antipyretics
0.662 0.338 0.000
M82 Osteoporosis in diseases classified elsewhere
0.661 0.339 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.339 0.000
T87 Complications peculiar to reattachment and amputation
0.661 0.339 0.000
I67 Other cerebrovascular diseases
0.660 0.340 0.000
I70.9 Generalised and unspecified atherosclerosis
0.660 0.340 0.000
I70.8 Atherosclerosis of other arteries
0.660 0.340 0.000
I70.1 Atherosclerosis of renal artery
0.660 0.340 0.000
S80.9 Superficial injury of lower leg, unspecified
0.660 0.340 0.000
M83 Adult osteomalacia
0.659 0.340 0.000
O21.0 Mild hyperemesis gravidarum
0.658 0.342 0.000
Y44 Agents primarily affecting blood constituents
0.658 0.342 0.000
S59 Other and unspecified injuries of forearm
0.658 0.342 0.000
S58 Traumatic amputation of forearm
0.658 0.342 0.000
S57 Crushing injury of forearm
0.658 0.342 0.000
S55 Injury of blood vessels at forearm level
0.658 0.342 0.000
S54 Injury of nerves at forearm level
0.658 0.342 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.658 0.342 0.000
M54.5 Low back pain
0.657 0.343 0.000
S27.2 Traumatic heamopneumothorax
0.657 0.343 0.000
S52.0 Fracture of upper end of ulna
0.657 0.343 0.000
M54.8 Other dorsalgia
0.656 0.344 0.000
M25.56 Pain in joint (Lower leg)
0.656 0.344 0.000
Y42.7 Androgens and anabolic congeners
0.655 0.345 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.654 0.345 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.654 0.345 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.654 0.345 0.000
T42.3 Barbiturates
0.654 0.345 0.000
T42.2 Succinimides and oxazolidinediones
0.654 0.345 0.000
T42.0 Hydantoin derivatives
0.654 0.345 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
S64 Injury of nerves at wrist and hand level
0.654 0.346 0.000
T86.4 Liver transplant failure and rejection
0.653 0.347 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.653 0.347 0.000
H74.1 Adhesive middle ear disease
0.652 0.348 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.651 0.349 0.000
W08 Fall involving other furniture
0.650 0.350 0.000
T93.1 Sequelae of fracture of femur
0.650 0.350 0.000
Y45.4 Antirheumatics
0.649 0.350 0.000
Y00 Assault by blunt object
0.649 0.351 0.000
M25.3 Other instability of joint
0.648 0.351 0.000
T20 Burn and corrosion of head and neck
0.647 0.353 0.000
S83.2 Tear of meniscus, current
0.646 0.354 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.645 0.355 0.000
S02.3 Fracture of orbital floor
0.645 0.355 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.644 0.356 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.644 0.356 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.644 0.356 0.000
S52.8 Fracture of other parts of forearm
0.644 0.356 0.000
H74.4 Polyp of middle ear
0.644 0.356 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.644 0.356 0.000
M25.88 Other specified joint disorders (Other)
0.644 0.356 0.000
M25.83 Other specified joint disorders (Forearm)
0.644 0.356 0.000
M25.82 Other specified joint disorders (Upper arm)
0.644 0.356 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.644 0.356 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.644 0.356 0.000
W14 Fall from tree
0.644 0.356 0.000
W12 Fall on and from scaffolding
0.644 0.356 0.000
W11 Fall on and from ladder
0.644 0.356 0.000
W09 Fall involving playground equipment
0.644 0.356 0.000
W05 Fall involving wheelchair
0.644 0.356 0.000
W04 Fall while being carried or supported by other persons
0.644 0.356 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.644 0.356 0.000
W00 Fall on same level involving ice and snow
0.644 0.356 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.643 0.357 0.000
S72.30 Fracture of shaft of femur (closed)
0.643 0.357 0.000
M65 Synovitis and tenosynovitis
0.642 0.357 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.642 0.357 0.000
M05-M14 Inflammatory polyarthropathies
0.642 0.357 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.642 0.358 0.000
H60 Otitis externa
0.642 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.642 0.358 0.000
S02.0 Fracture of vault of skull
0.641 0.359 0.000
Y54.5 Other diuretics
0.641 0.359 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.641 0.359 0.000
W59 Bitten or crushed by other reptiles
0.641 0.359 0.000
W58 Bitten or struck by crocodile or alligator
0.641 0.359 0.000
W56 Contact with marine animal
0.641 0.359 0.000
W54 Bitten or struck by dog
0.641 0.359 0.000
W53 Bitten by rat
0.641 0.359 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.641 0.359 0.000
W51 Striking against or bumped into by another person
0.641 0.359 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.641 0.359 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.641 0.359 0.000
S20 Superficial injury of thorax
0.640 0.360 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.640 0.360 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.640 0.360 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.637 0.363 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.636 0.363 0.000
S81.8 Open wound of other parts of lower leg
0.636 0.364 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.636 0.364 0.000
T51 Toxic effect of alcohol
0.636 0.364 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.636 0.364 0.000
O20.0 Threatened abortion
0.636 0.364 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.635 0.365 0.000
S62.3 Fracture of other metacarpal bone
0.634 0.366 0.000
M87 Osteonecrosis
0.634 0.366 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.633 0.367 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.633 0.367 0.000
H68 Eustachian salpingitis and obstruction
0.633 0.367 0.000
H67 Otitis media in diseases classified elsewhere
0.633 0.367 0.000
M62 Other disorders of muscle
0.633 0.367 0.000
M25.50 Pain in joint (Multiple sites)
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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