TreeWAS – Variant ID: rs7690819

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.799	0.201
K51 Ulcerative colitis	0.000	0.806	0.194
K51.4 Pseudopolyposis of colon	0.000	0.821	0.179
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.823	0.177
K51.8 Other ulcerative colitis	0.000	0.823	0.177
K51.5 Mucosal proctocolitis	0.000	0.839	0.161
K51.9 Ulcerative colitis, unspecified	0.000	0.850	0.150
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.861	0.139
R44.1 Visual hallucinations	0.000	0.935	0.065
I24.8 Other forms of acute ischaemic heart disease	0.000	0.935	0.065
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.936	0.064
R44.3 Hallucinations, unspecified	0.000	0.938	0.062
K51.2 Ulcerative (chronic) proctitis	0.000	0.940	0.060
R44.0 Auditory hallucinations	0.000	0.941	0.059
R44.2 Other hallucinations	0.000	0.946	0.053
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.960	0.040
I24 Other acute ischaemic heart diseases	0.000	0.961	0.039
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.967	0.033
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.968	0.032
I24.1 Dressler's syndrome	0.000	0.975	0.025
K50-K52 Noninfective enteritis and colitis	0.000	0.978	0.022
D80.1 Nonfamilial hypogammaglobulinaemia	0.019	0.981	0.000
D86.0 Sarcoidosis of lung	0.019	0.981	0.000
D80 Immunodeficiency with predominantly antibody defects	0.018	0.982	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.016	0.984	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.015	0.985	0.000
D86 Sarcoidosis	0.015	0.985	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.985	0.015
D80-D89 Certain disorders involving the immune mechanism	0.014	0.986	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.014	0.986	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.986	0.014
D80.8 Other immunodeficiencies with predominantly antibody defects	0.013	0.987	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.013	0.987	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.013	0.987	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.013	0.987	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.013	0.987	0.000
C61 Malignant neoplasm of prostate	0.013	0.987	0.000
D86.1 Sarcoidosis of lymph nodes	0.012	0.987	0.000
D84 Other immunodeficiencies	0.012	0.988	0.000
Z93 Artificial opening status	0.000	0.988	0.012
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.988	0.012
K52.1 Toxic gastro-enteritis and colitis	0.000	0.988	0.012
K52 Other non-infective gastro-enteritis and colitis	0.000	0.989	0.011
Z93.2 Ileostomy status	0.000	0.989	0.011
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.011	0.989	0.000
D83 Common variable immunodeficiency	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.011	0.989	0.000
D81 Combined immunodeficiencies	0.010	0.990	0.000
D86.3 Sarcoidosis of skin	0.010	0.990	0.000
D84.1 Defects in the complement system	0.010	0.990	0.000
Z93.3 Colostomy status	0.000	0.990	0.010
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.990	0.010
Z93.1 Gastrostomy status	0.000	0.990	0.010
D82 Immunodeficiency associated with other major defects	0.009	0.990	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.990	0.010
Z93.9 Artificial opening status, unspecified	0.000	0.991	0.009
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.009	0.991	0.000
Z93.5 Cystostomy status	0.000	0.991	0.009
D84.8 Other specified immunodeficiencies	0.009	0.991	0.000
D83.9 Common variable immunodeficiency, unspecified	0.009	0.991	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.991	0.009
R45 Symptoms and signs involving emotional state	0.000	0.992	0.008
H20.9 Iridocyclitis, unspecified	0.000	0.992	0.008
R46 Symptoms and signs involving appearance and behaviour	0.000	0.992	0.008
D83.8 Other common variable immunodeficiencies	0.008	0.992	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.008	0.992	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.008	0.992	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.008	0.992	0.000
Z93.8 Other artificial opening status	0.000	0.992	0.008
K81.9 Cholecystitis, unspecified	0.000	0.992	0.008
D35.2 Pituitary gland	0.000	0.992	0.008
D81.9 Combined immunodeficiency, unspecified	0.008	0.992	0.000
D81.8 Other combined immunodeficiencies	0.008	0.992	0.000
D81.7 Major histocompatibility complex class II deficiency	0.008	0.992	0.000
D81.6 Major histocompatibility complex class I deficiency	0.008	0.992	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.008	0.992	0.000
D81.4 Nezelof's syndrome	0.008	0.992	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.008	0.992	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.008	0.992	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.008	0.992	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.008	0.992	0.000
K52.3 Indeterminate colitis	0.000	0.992	0.007
H20 Iridocyclitis	0.000	0.992	0.008
R45.4 Irritability and anger	0.000	0.993	0.007
H20.8 Other iridocyclitis	0.000	0.993	0.007
K81.0 Acute cholecystitis	0.000	0.993	0.007
R46.0 Very low level of personal hygiene	0.000	0.993	0.007
D82.9 Immunodeficiency associated with major defect, unspecified	0.007	0.993	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.007	0.993	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.007	0.993	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.007	0.993	0.000
D82.2 Immunodeficiency with short-limbed stature	0.007	0.993	0.000
D82.0 Wiskott-Aldrich syndrome	0.007	0.993	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.993	0.007
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.993	0.007
R45.2 Unhappiness	0.000	0.993	0.007
R45.5 Hostility	0.000	0.993	0.007
R45.1 Restlessness and agitation	0.000	0.993	0.007
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
R40 Somnolence, stupor and coma	0.000	0.993	0.007
H20.0 Acute and subacute iridocyclitis	0.000	0.993	0.007
E89.0 Postprocedural hypothyroidism	0.007	0.993	0.000
R45.6 Physical violence	0.000	0.994	0.006
R45.3 Demoralisation and apathy	0.000	0.994	0.006
D82.1 Di George's syndrome	0.006	0.994	0.000
R40.1 Stupor	0.000	0.994	0.006
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.994	0.006
R46.6 Undue concern and preoccupation with stressful events	0.000	0.994	0.006
R46.5 Suspiciousness and marked evasiveness	0.000	0.994	0.006
R46.3 Overactivity	0.000	0.994	0.006
R46.1 Bizarre personal appearance	0.000	0.994	0.006
R45.7 State of emotional shock and stress, unspecified	0.000	0.994	0.006
R45.0 Nervousness	0.000	0.994	0.006
R46.2 Strange and inexplicable behaviour	0.000	0.994	0.006
H20.1 Chronic iridocyclitis	0.000	0.994	0.006
R43 Disturbances of smell and taste	0.000	0.994	0.006
K81 Cholecystitis	0.000	0.994	0.006
H20.2 Lens-induced iridocyclitis	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.005	0.994	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
R40.2 Coma, unspecified	0.000	0.995	0.005
R46.4 Slowness and poor responsiveness	0.000	0.995	0.005
O66 Other obstructed labour	0.000	0.995	0.005
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.995	0.005
S82.10 Fracture of upper end of tibia (closed)	0.005	0.995	0.000
Z93.0 Tracheostomy status	0.000	0.995	0.005
R45.8 Other symptoms and signs involving emotional state	0.000	0.995	0.005
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.005	0.995	0.000
R43.1 Parosmia	0.000	0.995	0.004
K81.8 Other cholecystitis	0.000	0.996	0.004
R43.2 Parageusia	0.000	0.996	0.004
A41.5 Septicaemia due to other Gram-negative organisms	0.004	0.996	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.004	0.996	0.000
R43.0 Anosmia	0.000	0.996	0.004
H43.3 Other vitreous opacities	0.000	0.996	0.004
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.000	0.996	0.004
A41.1 Septicaemia due to other specified staphylococcus	0.004	0.996	0.000
A41 Other septicaemia	0.004	0.996	0.000
C60-C63 Malignant neoplasms of male genital organs	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
F30.9 Manic episode, unspecified	0.004	0.996	0.000
O66.8 Other specified obstructed labour	0.000	0.996	0.004
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.996	0.004
O66.1 Obstructed labour due to locked twins	0.000	0.996	0.004
H17.9 Corneal scar and opacity, unspecified	0.000	0.996	0.004
A41.8 Other specified septicaemia	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.996	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
F10.0 Acute intoxication	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.000	0.997	0.003
R22.1 Localised swelling, mass and lump, neck	0.003	0.997	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.000	0.997	0.003
A41.4 Septicaemia due to anaerobes	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.003	0.997	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.003	0.997	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.997	0.003
C62 Malignant neoplasm of testis	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
N27.0 Small kidney, unilateral	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.000	0.997	0.003
B35.3 Tinea pedis	0.000	0.997	0.003
H17 Corneal scars and opacities	0.000	0.997	0.003
H25.1 Senile nuclear cataract	0.000	0.997	0.003
A41.2 Septicaemia due to unspecified staphylococcus	0.003	0.997	0.000
H25.8 Other senile cataract	0.000	0.997	0.003
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
W13.9 Unspecified place	0.003	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
H02.9 Disorder of eyelid, unspecified	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
C63.9 Male genital organ, unspecified	0.002	0.997	0.000
C63.8 Overlapping lesion of male genital organs	0.002	0.997	0.000
C63.7 Other specified male genital organs	0.002	0.997	0.000
C63.1 Spermatic cord	0.002	0.997	0.000
C63.0 Epididymis	0.002	0.997	0.000
C62.0 Undescended testis	0.002	0.997	0.000
C63.2 Scrotum	0.002	0.997	0.000
O12.1 Gestational proteinuria	0.002	0.997	0.000
O41.0 Oligohydramnios	0.000	0.998	0.002
A41.9 Septicaemia, unspecified	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.998	0.002
C62.9 Testis, unspecified	0.002	0.998	0.000
C62.1 Descended testis	0.002	0.998	0.000
C60 Malignant neoplasm of penis	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
R41.1 Anterograde amnesia	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
H17.1 Other central corneal opacity	0.000	0.998	0.002
H17.0 Adherent leukoma	0.000	0.998	0.002
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.998	0.002
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.000	0.998	0.002
R41.3 Other amnesia	0.000	0.998	0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.998	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.002
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H16 Keratitis	0.000	0.998	0.002
H17.8 Other corneal scars and opacities	0.000	0.998	0.002
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
N27 Small kidney of unknown cause	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
K01.0 Embedded teeth	0.000	0.998	0.002
N27.1 Small kidney, bilateral	0.000	0.998	0.002
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.002	0.998	0.000
C60.8 Overlapping lesion of penis	0.002	0.998	0.000
C60.2 Body of penis	0.002	0.998	0.000
H16.8 Other keratitis	0.000	0.998	0.002
S49.8 Other specified injuries of shoulder and upper arm	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
M45 Ankylosing spondylitis	0.000	0.998	0.002
H25 Senile cataract	0.000	0.998	0.002
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.998	0.002
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
C60.0 Prepuce	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.000	0.998	0.002
O15 Eclampsia	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.998	0.002
M19.94 Arthrosis, unspecified (Hand)	0.000	0.998	0.002
S49.7 Multiple injuries of shoulder and upper arm	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
C60.1 Glans penis	0.001	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
H15 Disorders of sclera	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.000	0.998	0.002
M14.6 Neuropathic arthropathy	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
N27.9 Small kidney, unspecified	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.000	0.998	0.002
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.998	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.998	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.998	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
C60.9 Penis, unspecified	0.001	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
C67.6 Ureteric orifice	0.002	0.998	0.000
X23.0 Home	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.000	0.998	0.001
O15.9 Eclampsia, unspecified as to time period	0.001	0.998	0.000
O15.2 Eclampsia in the puerperium	0.001	0.998	0.000
O15.1 Eclampsia in labour	0.001	0.998	0.000
O15.0 Eclampsia in pregnancy	0.001	0.998	0.000
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
H16.2 Keratoconjunctivitis	0.000	0.998	0.001
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.998	0.001
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
S70.1 Contusion of thigh	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.001
H25.2 Senile cataract, morgagnian type	0.000	0.998	0.001
K80.8 Other cholelithiasis	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.000	0.998	0.001
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.998	0.000
Q18.7 Microcheilia	0.001	0.998	0.000
Q18.6 Macrocheilia	0.001	0.998	0.000
Q18.5 Microstomia	0.001	0.998	0.000
Q18.4 Macrostomia	0.001	0.998	0.000
Q18.3 Webbing of neck	0.001	0.998	0.000
Q18.2 Other branchial cleft malformations	0.001	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.998	0.001
H25.9 Senile cataract, unspecified	0.000	0.998	0.002
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
A87.9 Viral meningitis, unspecified	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.000	0.998	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.998	0.000
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
W22.2 School, other institution and public administrative area	0.001	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.001
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.001
S70.8 Other superficial injuries of hip and thigh	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
H15.0 Scleritis	0.000	0.999	0.001
K27.7 Chronic without haemorrhage or perforation	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.999	0.001
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.999	0.001
H33.0 Retinal detachment with retinal break	0.000	0.999	0.001
K70.0 Alcoholic fatty liver	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.999	0.001
E89.3 Postprocedural hypopituitarism	0.001	0.999	0.000
H26.8 Other specified cataract	0.000	0.999	0.001
O12.0 Gestational oedema	0.001	0.999	0.000
W13.4 Street and highway	0.001	0.999	0.000
W13 Fall from, out of or through building or structure	0.001	0.999	0.000
S27.1 Traumatic haemothorax	0.000	0.999	0.001
S52.30 Fracture of shaft of radius (closed)	0.001	0.999	0.000
D38.1 Trachea, bronchus and lung	0.000	0.999	0.001
R73.0 Abnormal glucose tolerance test	0.000	0.999	0.001
X23.9 Unspecified place	0.001	0.999	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.001	0.999	0.000
O14.2 HELLP syndrome	0.001	0.999	0.000
V48.4 Person injured while boarding or alighting	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.999	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
X23 Contact with hornets, wasps and bees	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
H15.1 Episcleritis	0.000	0.999	0.001
H57.1 Ocular pain	0.000	0.999	0.001
S50.9 Superficial injury of forearm, unspecified	0.001	0.999	0.000
X23.8 Other specified place	0.001	0.999	0.000
W13.8 Other specified place	0.001	0.999	0.000
W13.0 Home	0.001	0.999	0.000
W13.7 Farm	0.001	0.999	0.000
W13.6 Industrial and construction area	0.001	0.999	0.000
W13.5 Trade and service area	0.001	0.999	0.000
W13.3 Sports and athletics area	0.001	0.999	0.000
W13.2 School, other institution and public administrative area	0.001	0.999	0.000
W13.1 Residential institution	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
S82.11 Fracture of upper end of tibia (open)	0.001	0.999	0.000
S70 Superficial injury of hip and thigh	0.001	0.999	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.001	0.999	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.001	0.999	0.000
R85.7 Abnormal histological findings	0.001	0.999	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.001	0.999	0.000
T18.0 Foreign body in mouth	0.001	0.999	0.000
H57 Other disorders of eye and adnexa	0.000	0.999	0.001
S20.8 Superficial injuries of other and unspecified parts of thorax	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
X23.7 Farm	0.001	0.999	0.000
X23.6 Industrial and construction area	0.001	0.999	0.000
X23.5 Trade and service area	0.001	0.999	0.000
X23.4 Street and highway	0.001	0.999	0.000
X23.3 Sports and athletics area	0.001	0.999	0.000
X23.2 School, other institution and public administrative area	0.001	0.999	0.000
X23.1 Residential institution	0.001	0.999	0.000
F30 Manic episode	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.999	0.001
E61.1 Iron deficiency	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.999	0.001
W13.08 Fall from, out of or through building or structure; Home; While engaged in other specified activities	0.001	0.999	0.000
W13.89 Fall from, out of or through building or structure; Other specified places; During unspecified activity	0.001	0.999	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.001	0.999	0.000
M51.8 Other specified intervertebral disk disorders	0.001	0.999	0.000
N02.9 Unspecified	0.000	0.999	0.001
C49.0 Connective and soft tissue of head, face and neck	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.999	0.001
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.999	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
D72.8 Other specified disorders of white blood cells	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.999	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.999	0.001
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
F30.8 Other manic episodes	0.001	0.999	0.000
F30.1 Mania without psychotic symptoms	0.001	0.999	0.000
R84.9 Unspecified abnormal finding	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
H18.6 Keratoconus	0.001	0.999	0.000
I77.6 Arteritis, unspecified	0.000	0.999	0.001
M50.3 Other cervical disk degeneration	0.001	0.999	0.000
S70.0 Contusion of hip	0.001	0.999	0.000
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.999	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.999	0.001
M25.55 Pain in joint (Pelvic region and thigh)	0.001	0.999	0.000
S42.00 Fracture of clavicle (closed)	0.001	0.999	0.000
B35.6 Tinea cruris	0.000	0.999	0.001
G00.9 Bacterial meningitis, unspecified	0.000	0.999	0.001
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.999	0.001
S82.01 Fracture of patella (open)	0.000	0.999	0.001
B02.8 Zoster with other complications	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.000	0.999	0.001
B19.9 Unspecified viral hepatitis without coma	0.001	0.999	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.001	0.999	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.999	0.001
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.001	0.999	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.001	0.999	0.000
G03.9 Meningitis, unspecified	0.000	0.999	0.001
H57.0 Anomalies of pupillary function	0.000	0.999	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.001	0.999	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.000	0.999	0.001
R84.8 Other abnormal findings	0.001	0.999	0.000
R84.4 Abnormal immunological findings	0.001	0.999	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R84.1 Abnormal level of hormones	0.001	0.999	0.000
R84.0 Abnormal level of enzymes	0.001	0.999	0.000
S80.9 Superficial injury of lower leg, unspecified	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.999	0.001
K27 Peptic ulcer, site unspecified	0.001	0.999	0.000
S79 Other and unspecified injuries of hip and thigh	0.001	0.999	0.000
T18 Foreign body in alimentary tract	0.001	0.999	0.000
G00.1 Pneumococcal meningitis	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.000	0.999	0.001
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.999	0.001
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.999	0.001
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.999	0.001
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.999	0.001
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.999	0.001
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.999	0.001
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.999	0.001
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.999	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.999	0.000
B35 Dermatophytosis	0.000	0.999	0.001
G00 Bacterial meningitis, not elsewhere classified	0.000	0.999	0.001
D05.1 Intraductal carcinoma in situ	0.001	0.999	0.000
F30.2 Mania with psychotic symptoms	0.001	0.999	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.001	0.999	0.000
K27.5 Chronic or unspecified with perforation	0.001	0.999	0.000
K27.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
K27.2 Acute with both haemorrhage and perforation	0.001	0.999	0.000
K27.1 Acute with perforation	0.001	0.999	0.000
K27.0 Acute with haemorrhage	0.001	0.999	0.000
K38.1 Appendicular concretions	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.001	0.999	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.999	0.000
S42.0 Fracture of clavicle	0.001	0.999	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations