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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76938821
log Bayes Factor = 8.96632
Chromosome 5   position 114,706,752  (GRCh37) Explore rs76938821 on Ensembl!
Variant rs76938821 is part of Cluster X0048

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.990 0.010 0.000
D00-D09 In situ neoplasms
0.986 0.014 0.000
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.981 0.019 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.973 0.027 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.973 0.027 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.972 0.028 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.967 0.033 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.965 0.035 0.000
O36 Maternal care for other known or suspected foetal problems
0.963 0.037 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.962 0.038 0.000
C34 Malignant neoplasm of bronchus and lung
0.958 0.042 0.000
S40-S49 Injuries to the shoulder and upper arm
0.958 0.042 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.950 0.050 0.000
C34.9 Bronchus or lung, unspecified
0.948 0.052 0.000
Q60-Q64 Congenital malformations of the urinary system
0.942 0.058 0.000
O43 Placental disorders
0.937 0.063 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.936 0.064 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.935 0.065 0.000
Y57 Other and unspecified drugs and medicaments
0.933 0.067 0.000
S20-S29 Injuries to the thorax
0.930 0.070 0.000
X50-X57 Overexertion, travel and privation
0.929 0.071 0.000
D04 Carcinoma in situ of skin
0.924 0.076 0.000
O36.8 Maternal care for other specified foetal problems
0.922 0.078 0.000
T90 Sequelae of injuries of head
0.921 0.079 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.920 0.080 0.000
D80-D89 Certain disorders involving the immune mechanism
0.919 0.081 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.914 0.086 0.000
D03 Melanoma in situ
0.912 0.088 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.912 0.088 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
Chapter VI Diseases of the nervous system
0.910 0.090 0.000
Y57.9 Drug or medicament, unspecified
0.900 0.100 0.000
D86 Sarcoidosis
0.899 0.101 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.899 0.101 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.898 0.102 0.000
Q61 Cystic kidney disease
0.893 0.107 0.000
C79.2 Secondary malignant neoplasm of skin
0.889 0.111 0.000
O43.8 Other placental disorders
0.889 0.111 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.888 0.112 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.887 0.113 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.886 0.114 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.885 0.115 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.883 0.117 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.883 0.117 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.881 0.119 0.000
M70-M79 Other soft tissue disorders
0.868 0.132 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.868 0.132 0.000
X51 Travel and motion
0.867 0.133 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.867 0.133 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.867 0.133 0.000
T79-T79 Certain early complications of trauma
0.866 0.134 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.865 0.135 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.865 0.135 0.000
M79.8 Other specified soft tissue disorders
0.863 0.137 0.000
T51 Toxic effect of alcohol
0.857 0.143 0.000
X60-X84 Intentional self-harm
0.854 0.146 0.000
Q50-Q56 Congenital malformations of genital organs
0.853 0.147 0.000
S27 Injury of other and unspecified intrathoracic organs
0.851 0.149 0.000
S42 Fracture of shoulder and upper arm
0.850 0.150 0.000
X20-X29 Contact with venomous animals and plants
0.850 0.150 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.850 0.150 0.000
O41 Other disorders of amniotic fluid and membranes
0.845 0.155 0.000
O80-O84 Delivery
0.845 0.155 0.000
Q61.3 Polycystic kidney, unspecified
0.844 0.156 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.841 0.159 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.841 0.159 0.000
M80-M85 Disorders of bone density and structure
0.840 0.160 0.000
D04.3 Skin of other and unspecified parts of face
0.839 0.161 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.834 0.166 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.831 0.169 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.831 0.169 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.828 0.172 0.000
T63 Toxic effect of contact with venomous animals
0.826 0.174 0.000
D86.3 Sarcoidosis of skin
0.825 0.175 0.000
T21 Burn and corrosion of trunk
0.823 0.177 0.000
X51.9 Unspecified place
0.823 0.177 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.822 0.178 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.820 0.180 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.820 0.180 0.000
C32 Malignant neoplasm of larynx
0.818 0.182 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.816 0.184 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.816 0.184 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.814 0.186 0.000
S90-S99 Injuries to the ankle and foot
0.812 0.188 0.000
O71 Other obstetric trauma
0.811 0.189 0.000
C80 Malignant neoplasm without specification of site
0.809 0.191 0.000
O21 Excessive vomiting in pregnancy
0.809 0.191 0.000
Chapter I Certain infectious and parasitic diseases
0.807 0.193 0.000
S10-S19 Injuries to the neck
0.806 0.194 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.805 0.195 0.000
D46 Myelodysplastic syndromes
0.804 0.196 0.000
D86.9 Sarcoidosis, unspecified
0.804 0.196 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.804 0.196 0.000
T18 Foreign body in alimentary tract
0.803 0.197 0.000
T59 Toxic effect of other gases, fumes and vapours
0.802 0.198 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.800 0.200 0.000
G00 Bacterial meningitis, not elsewhere classified
0.799 0.201 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.796 0.204 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.795 0.205 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.795 0.205 0.000
D69 Purpura and other haemorrhagic conditions
0.794 0.206 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.794 0.206 0.000
S40 Superficial injury of shoulder and upper arm
0.792 0.208 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.791 0.209 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.791 0.209 0.000
X10-X19 Contact with heat and hot substances
0.789 0.211 0.000
T51.0 Ethanol
0.789 0.211 0.000
O73 Retained placenta and membranes, without haemorrhage
0.788 0.212 0.000
O46.9 Antepartum haemorrhage, unspecified
0.788 0.212 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.787 0.213 0.000
T98 Sequelae of other and unspecified effects of external causes
0.784 0.216 0.000
Y44 Agents primarily affecting blood constituents
0.784 0.216 0.000
C79.6 Secondary malignant neoplasm of ovary
0.782 0.218 0.000
M79.1 Myalgia
0.782 0.218 0.000
T17 Foreign body in respiratory tract
0.779 0.221 0.000
D04.7 Skin of lower limb, including hip
0.778 0.222 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.776 0.224 0.000
O61 Failed induction of labour
0.775 0.225 0.000
M20-M25 Other joint disorders
0.775 0.225 0.000
O00-O08 Pregnancy with abortive outcome
0.774 0.226 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.774 0.226 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.773 0.227 0.000
O30 Multiple gestation
0.771 0.229 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.771 0.229 0.000
T25 Burn and corrosion of ankle and foot
0.770 0.230 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.769 0.231 0.000
M85 Other disorders of bone density and structure
0.769 0.231 0.000
O85-O92 Complications predominantly related to the puerperium
0.768 0.232 0.000
V98-V99 Other and unspecified transport accidents
0.768 0.232 0.000
M35 Other systemic involvement of connective tissue
0.766 0.234 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.766 0.234 0.000
Q43 Other congenital malformations of intestine
0.765 0.235 0.000
T90.0 Sequelae of superficial injury of head
0.763 0.237 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.762 0.238 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.761 0.239 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.760 0.240 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.760 0.240 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.759 0.241 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.759 0.241 0.000
O34.1 Maternal care for tumour of corpus uteri
0.759 0.241 0.000
O36.9 Maternal care for foetal problem, unspecified
0.758 0.242 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.758 0.242 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.757 0.243 0.000
M80 Osteoporosis with pathological fracture
0.756 0.244 0.000
D68 Other coagulation defects
0.755 0.245 0.000
A30-A49 Other bacterial diseases
0.754 0.246 0.000
C92 Myeloid leukaemia
0.753 0.247 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.752 0.248 0.000
T90.9 Sequelae of unspecified injury of head
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.749 0.251 0.000
O36.5 Maternal care for poor foetal growth
0.749 0.251 0.000
W75-W84 Other accidental threats to breathing
0.749 0.251 0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.747 0.253 0.000
M35.0 Sicca syndrome [Sjogren]
0.746 0.254 0.000
D07.4 Penis
0.746 0.254 0.000
S27.0 Traumatic pneumothorax
0.745 0.254 0.000
D86.8 Sarcoidosis of other and combined sites
0.745 0.255 0.000
X23 Contact with hornets, wasps and bees
0.745 0.255 0.000
Q61.2 Polycystic kidney, adult type
0.745 0.255 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.744 0.255 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.744 0.256 0.000
Q00-Q07 Congenital malformations of the nervous system
0.743 0.257 0.000
Chapter V Mental and behavioural disorders
0.743 0.257 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.257 0.000
Y45.2 Propionic acid derivatives
0.743 0.257 0.000
C81 Hodgkin's disease
0.742 0.258 0.000
T23 Burn and corrosion of wrist and hand
0.740 0.260 0.000
T65 Toxic effect of other and unspecified substances
0.739 0.261 0.000
C34.2 Middle lobe, bronchus or lung
0.739 0.261 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.739 0.261 0.000
T91 Sequelae of injuries of neck and trunk
0.738 0.262 0.000
O45 Premature separation of placenta [abruptio placentae]
0.738 0.262 0.000
G00.1 Pneumococcal meningitis
0.738 0.262 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.737 0.263 0.000
Y49.5 Other antipsychotics and neuroleptics
0.737 0.263 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.736 0.264 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.736 0.264 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.736 0.264 0.000
A41 Other septicaemia
0.736 0.264 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.736 0.264 0.000
S91 Open wound of ankle and foot
0.735 0.265 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.734 0.266 0.000
Q53 Undescended testicle
0.733 0.267 0.000
T00-T07 Injuries involving multiple body regions
0.733 0.267 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.732 0.268 0.000
M79.2 Neuralgia and neuritis, unspecified
0.732 0.268 0.000
O21.0 Mild hyperemesis gravidarum
0.731 0.269 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.731 0.269 0.000
T56 Toxic effect of metals
0.731 0.269 0.000
W50-W64 Exposure to animate mechanical forces
0.731 0.269 0.000
D66 Hereditary factor VIII deficiency
0.729 0.271 0.000
Q63 Other congenital malformations of kidney
0.729 0.271 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.728 0.272 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.727 0.273 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.727 0.273 0.000
T63.4 Venom of other arthropods
0.724 0.276 0.000
X50 Overexertion and strenuous or repetitive movements
0.724 0.276 0.000
T92 Sequelae of injuries of upper limb
0.724 0.276 0.000
G90-G99 Other disorders of the nervous system
0.723 0.277 0.000
S41 Open wound of shoulder and upper arm
0.722 0.277 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.722 0.278 0.000
O26.8 Other specified pregnancy-related conditions
0.722 0.278 0.000
D41.4 Bladder
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.720 0.280 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.720 0.280 0.000
C95 Leukaemia of unspecified cell type
0.718 0.281 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.718 0.282 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.718 0.282 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
O80 Single spontaneous delivery
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Y57.5 X-ray contrast media
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
O33 Maternal care for known or suspected disproportion
0.714 0.286 0.000
O31 Complications specific to multiple gestation
0.714 0.286 0.000
T20 Burn and corrosion of head and neck
0.713 0.286 0.000
D07.1 Vulva
0.713 0.287 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.712 0.288 0.000
D07.5 Prostate
0.711 0.289 0.000
O43.1 Malformation of placenta
0.710 0.290 0.000
T66-T78 Other and unspecified effects of external causes
0.710 0.290 0.000
Q35-Q37 Cleft lip and cleft palate
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.710 0.290 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.710 0.290 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
A41.9 Septicaemia, unspecified
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
T90.8 Sequelae of other specified injuries of head
0.707 0.293 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.707 0.293 0.000
S42.3 Fracture of shaft of humerus
0.705 0.295 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.705 0.295 0.000
O63 Long labour
0.704 0.296 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
T58 Toxic effect of carbon monoxide
0.704 0.296 0.000
D69.6 Thrombocytopenia, unspecified
0.703 0.297 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.703 0.297 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.703 0.297 0.000
C31 Malignant neoplasm of accessory sinuses
0.703 0.297 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.703 0.297 0.000
C37 Malignant neoplasm of thymus
0.703 0.297 0.000
C33 Malignant neoplasm of trachea
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.703 0.297 0.000
S42.1 Fracture of scapula
0.703 0.297 0.000
Y00-Y09 Assault
0.702 0.298 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.702 0.298 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.702 0.298 0.000
Q64 Other congenital malformations of urinary system
0.701 0.299 0.000
Y45.0 Opioids and related analgesics
0.700 0.300 0.000
T17.2 Foreign body in pharynx
0.700 0.300 0.000
C83.1 Small cleaved cell (diffuse)
0.699 0.301 0.000
D09 Carcinoma in situ of other and unspecified sites
0.698 0.301 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.698 0.302 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.698 0.302 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.698 0.302 0.000
M35.3 Polymyalgia rheumatica
0.698 0.302 0.000
Y59 Other and unspecified vaccines and biological substances
0.697 0.303 0.000
Y58 Bacterial vaccines
0.697 0.303 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.697 0.303 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
D04.6 Skin of upper limb, including shoulder
0.696 0.304 0.000
S27.1 Traumatic haemothorax
0.695 0.305 0.000
T93 Sequelae of injuries of lower limb
0.694 0.306 0.000
T90.4 Sequelae of injury of eye and orbit
0.694 0.306 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.694 0.306 0.000
S22.2 Fracture of sternum
0.694 0.306 0.000
T62 Toxic effect of other noxious substances eaten as food
0.693 0.307 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.693 0.307 0.000
T60 Toxic effect of pesticides
0.693 0.307 0.000
T57 Toxic effect of other inorganic substances
0.693 0.307 0.000
T54 Toxic effect of corrosive substances
0.693 0.307 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.693 0.307 0.000
T52 Toxic effect of organic solvents
0.693 0.307 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.693 0.307 0.000
T55 Toxic effect of soaps and detergents
0.693 0.307 0.000
S42.0 Fracture of clavicle
0.693 0.307 0.000
C76.3 Pelvis
0.693 0.307 0.000
M71 Other bursopathies
0.692 0.308 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
T95 Sequelae of burns, corrosions and frostbite
0.692 0.308 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.692 0.308 0.000
T31 Burns classified according to extent of body surface involved
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.691 0.309 0.000
S22.4 Multiple fractures of ribs
0.691 0.309 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.691 0.309 0.000
O36.2 Maternal care for hydrops foetalis
0.691 0.309 0.000
O36.1 Maternal care for other isoimmunisation
0.691 0.309 0.000
M79.9 Soft tissue disorder, unspecified
0.690 0.310 0.000
D04.2 Skin of ear and external auricular canal
0.690 0.310 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.689 0.311 0.000
C32.1 Supraglottis
0.689 0.311 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.688 0.312 0.000
S12 Fracture of neck
0.688 0.312 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
C34.8 Overlapping lesion of bronchus and lung
0.687 0.313 0.000
S48 Traumatic amputation of shoulder and upper arm
0.687 0.313 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.687 0.313 0.000
S44 Injury of nerves at shoulder and upper arm level
0.687 0.313 0.000
S47 Crushing injury of shoulder and upper arm
0.687 0.313 0.000
O16 Unspecified maternal hypertension
0.686 0.314 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.686 0.314 0.000
O81 Single delivery by forceps and vacuum extractor
0.686 0.314 0.000
G30-G32 Other degenerative diseases of the nervous system
0.685 0.315 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.684 0.315 0.000
Q44.6 Cystic disease of liver
0.683 0.317 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.683 0.317 0.000
D86.0 Sarcoidosis of lung
0.682 0.317 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.682 0.318 0.000
T21.3 Burn of third degree of trunk
0.681 0.319 0.000
G35 Multiple sclerosis
0.680 0.320 0.000
O71.4 Obstetric high vaginal laceration alone
0.680 0.320 0.000
C88 Malignant immunoproliferative diseases
0.680 0.320 0.000
Y45.5 4-Aminophenol derivatives
0.679 0.321 0.000
O62 Abnormalities of forces of labour
0.678 0.322 0.000
M85.8 Other specified disorders of bone density and structure
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.323 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.675 0.325 0.000
O32.0 Maternal care for unstable lie
0.673 0.327 0.000
O46.8 Other antepartum haemorrhage
0.673 0.327 0.000
D03.4 Melanoma in situ of scalp and neck
0.672 0.328 0.000
M31 Other necrotising vasculopathies
0.672 0.328 0.000
O43.9 Placental disorder, unspecified
0.672 0.328 0.000
O43.2 Morbidly adherent placenta
0.672 0.328 0.000
O43.0 Placental transfusion syndromes
0.672 0.328 0.000
T18.0 Foreign body in mouth
0.672 0.328 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.670 0.329 0.000
C94 Other leukaemias of specified cell type
0.670 0.329 0.000
C93 Monocytic leukaemia
0.670 0.329 0.000
C86 Other specified types of T/NK-cell lymphoma
0.670 0.329 0.000
T90.5 Sequelae of intracranial injury
0.670 0.330 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.670 0.330 0.000
O00 Ectopic pregnancy
0.670 0.330 0.000
Y57.7 Vitamins, not elsewhere classified
0.669 0.331 0.000
Y57.6 Other diagnostic agents
0.669 0.331 0.000
Y57.4 Pharmaceutical excipients
0.669 0.331 0.000
Y57.3 Alcohol deterrents
0.669 0.331 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.669 0.331 0.000
Y57.1 Lipotropic drugs
0.669 0.331 0.000
Y57.0 Appetite depressants [anorectics]
0.669 0.331 0.000
M82 Osteoporosis in diseases classified elsewhere
0.669 0.331 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.668 0.332 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.667 0.333 0.000
S26 Injury of heart
0.667 0.333 0.000
S25 Injury of blood vessels of thorax
0.667 0.333 0.000
S24 Injury of nerves and spinal cord at thorax level
0.667 0.333 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.667 0.333 0.000
S21 Open wound of thorax
0.667 0.333 0.000
X57 Unspecified privation
0.666 0.334 0.000
X54 Lack of water
0.666 0.334 0.000
X53 Lack of food
0.666 0.334 0.000
X52 Prolonged stay in weightless environment
0.666 0.334 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.666 0.334 0.000
C91 Lymphoid leukaemia
0.665 0.335 0.000
Q54 Hypospadias
0.664 0.336 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.664 0.336 0.000
D04.9 Skin, unspecified
0.663 0.337 0.000
D04.8 Skin of other sites
0.663 0.337 0.000
D04.1 Skin of eyelid, including canthus
0.663 0.337 0.000
D04.0 Skin of lip
0.663 0.337 0.000
O80.0 Spontaneous vertex delivery
0.662 0.338 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.338 0.000
D04.4 Skin of scalp and neck
0.662 0.338 0.000
T90.3 Sequelae of injury of cranial nerves
0.660 0.340 0.000
T90.1 Sequelae of open wound of head
0.660 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.660 0.340 0.000
D03.5 Melanoma in situ of trunk
0.660 0.340 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.660 0.340 0.000
Y57.8 Other drugs and medicaments
0.660 0.340 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.660 0.340 0.000
S22.5 Flail chest
0.659 0.340 0.000
W20-W49 Exposure to inanimate mechanical forces
0.659 0.341 0.000
D84 Other immunodeficiencies
0.659 0.341 0.000
D83 Common variable immunodeficiency
0.659 0.341 0.000
D82 Immunodeficiency associated with other major defects
0.659 0.341 0.000
D81 Combined immunodeficiencies
0.659 0.341 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.658 0.342 0.000
L05 Pilonidal cyst
0.658 0.342 0.000
O32.4 Maternal care for high head at term
0.658 0.342 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.658 0.342 0.000
O73.0 Retained placenta, without haemorrhage
0.657 0.343 0.000
M86-M90 Other osteopathies
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
A00-A09 Intestinal infectious diseases
0.656 0.344 0.000
T19 Foreign body in genito-urinary tract
0.656 0.344 0.000
T15 Foreign body on external eye
0.656 0.344 0.000
L10-L14 Bullous disorders
0.655 0.345 0.000
D03.9 Melanoma in situ, unspecified
0.654 0.346 0.000
D03.8 Melanoma in situ of other sites
0.654 0.346 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.654 0.346 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.654 0.346 0.000
D03.0 Melanoma in situ of lip
0.654 0.346 0.000
D67 Hereditary factor IX deficiency
0.654 0.346 0.000
Y52 Agents primarily affecting the cardiovascular system
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.346 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.653 0.347 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.652 0.347 0.000
T18.5 Foreign body in anus and rectum
0.652 0.348 0.000
O47 False labour
0.652 0.348 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.652 0.348 0.000
C34.1 Upper lobe, bronchus or lung
0.651 0.349 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.651 0.349 0.000
T59.9 Gases, fumes and vapours, unspecified
0.651 0.349 0.000
D01.3 Anus and anal canal
0.651 0.349 0.000
G90 Disorders of autonomic nervous system
0.651 0.349 0.000
D69.2 Other nonthrombocytopenic purpura
0.649 0.351 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.649 0.351 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.648 0.352 0.000
Y44.2 Anticoagulants
0.648 0.352 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.648 0.352 0.000
Q53.1 Undescended testicle, unilateral
0.647 0.353 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.646 0.354 0.000
S22.3 Fracture of rib
0.646 0.354 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.645 0.355 0.000
T46.1 Calcium-channel blockers
0.645 0.355 0.000
S27.3 Other injuries of lung
0.645 0.355 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.645 0.355 0.000
D86.1 Sarcoidosis of lymph nodes
0.645 0.355 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.645 0.355 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.645 0.355 0.000
Q45 Other congenital malformations of digestive system
0.644 0.355 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.644 0.355 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.644 0.355 0.000
Q40 Other congenital malformations of upper alimentary tract
0.644 0.355 0.000
Q39 Congenital malformations of oesophagus
0.644 0.355 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.644 0.356 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.356 0.000
O29 Complications of anaesthesia during pregnancy
0.644 0.356 0.000
O22 Venous complications in pregnancy
0.644 0.356 0.000
O25 Malnutrition in pregnancy
0.644 0.356 0.000
M76 Enthesopathies of lower limb, excluding foot
0.643 0.357 0.000
T16 Foreign body in ear
0.643 0.357 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.643 0.357 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.643 0.357 0.000
T21.0 Burn of unspecified degree of trunk
0.643 0.357 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.643 0.357 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.641 0.359 0.000
D48.0 Bone and articular cartilage
0.640 0.360 0.000
Q61.9 Cystic kidney disease, unspecified
0.640 0.360 0.000
Q61.8 Other cystic kidney diseases
0.640 0.360 0.000
Q61.5 Medullary cystic kidney
0.640 0.360 0.000
Q61.4 Renal dysplasia
0.640 0.360 0.000
Q61.1 Polycystic kidney, infantile type
0.640 0.360 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.639 0.360 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.639 0.361 0.000
X23.9 Unspecified place
0.639 0.361 0.000
M79.10 Myalgia (Multiple sites)
0.638 0.362 0.000
Y88 Sequelae of surgical and medical care as external cause
0.638 0.362 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.637 0.363 0.000
D80 Immunodeficiency with predominantly antibody defects
0.637 0.363 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.637 0.363 0.000
M79.5 Residual foreign body in soft tissue
0.637 0.363 0.000
D07.6 Other and unspecified male genital organs
0.637 0.363 0.000
D07.3 Other and unspecified female genital organs
0.637 0.363 0.000
D07.2 Vagina
0.637 0.363 0.000
D07.0 Endometrium
0.637 0.363 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.637 0.363 0.000
O36.4 Maternal care for intra-uterine death
0.636 0.364 0.000
Q68 Other congenital musculoskeletal deformities
0.636 0.364 0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.635 0.364 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.634 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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