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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76941853
log Bayes Factor = 20.227
Chromosome 6   position 12,651,314  (GRCh37) Explore rs76941853 on Ensembl!
Variant rs76941853 is part of Cluster X0001

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M17 Gonarthrosis [arthrosis of knee]
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
M17.1 Other primary gonarthrosis
0.991 0.009 0.000
M23 Internal derangement of knee
0.990 0.010 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.987 0.013 0.000
K70-K77 Diseases of liver
0.986 0.014 0.000
I50 Heart failure
0.985 0.015 0.000
M17.9 Gonarthrosis, unspecified
0.985 0.015 0.000
E00-E07 Disorders of thyroid gland
0.985 0.015 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.981 0.019 0.000
E03 Other hypothyroidism
0.976 0.024 0.000
J30-J39 Other diseases of upper respiratory tract
0.973 0.027 0.000
I50.9 Heart failure, unspecified
0.971 0.029 0.000
E65-E68 Obesity and other hyperalimentation
0.970 0.030 0.000
E03.9 Hypothyroidism, unspecified
0.966 0.034 0.000
G90-G99 Other disorders of the nervous system
0.966 0.034 0.000
Chapter V Mental and behavioural disorders
0.965 0.035 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.962 0.038 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.955 0.045 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.953 0.047 0.000
E66 Obesity
0.949 0.051 0.000
K76 Other diseases of liver
0.949 0.051 0.000
M19 Other arthrosis
0.948 0.052 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.947 0.053 0.000
F17.1 Harmful use
0.939 0.061 0.000
I35 Nonrheumatic aortic valve disorders
0.938 0.062 0.000
E66.8 Other obesity
0.935 0.065 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.931 0.069 0.000
K90-K93 Other diseases of the digestive system
0.925 0.075 0.000
M50-M54 Other dorsopathies
0.923 0.077 0.000
I42 Cardiomyopathy
0.918 0.082 0.000
I31 Other diseases of pericardium
0.916 0.084 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
M35 Other systemic involvement of connective tissue
0.912 0.088 0.000
J33 Nasal polyp
0.909 0.091 0.000
M25.4 Effusion of joint
0.909 0.091 0.000
Chapter II Neoplasms
0.909 0.091 0.000
M40-M43 Deforming dorsopathies
0.906 0.094 0.000
M22 Disorders of patella
0.904 0.096 0.000
M23.3 Other meniscus derangements
0.903 0.097 0.000
I38 Endocarditis, valve unspecified
0.900 0.100 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.897 0.103 0.000
J47 Bronchiectasis
0.895 0.105 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.895 0.105 0.000
K14 Diseases of tongue
0.889 0.111 0.000
I50.0 Congestive heart failure
0.889 0.111 0.000
G93 Other disorders of brain
0.888 0.112 0.000
I95 Hypotension
0.888 0.112 0.000
D10-D36 Benign neoplasms
0.886 0.114 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.880 0.120 0.000
I46 Cardiac arrest
0.879 0.121 0.000
Q60-Q64 Congenital malformations of the urinary system
0.873 0.127 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.871 0.129 0.000
M35.3 Polymyalgia rheumatica
0.870 0.130 0.000
M34 Systemic sclerosis
0.870 0.130 0.000
M19.9 Arthrosis, unspecified
0.869 0.131 0.000
I95.1 Orthostatic hypotension
0.868 0.132 0.000
M54 Dorsalgia
0.863 0.137 0.000
K70 Alcoholic liver disease
0.861 0.139 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.861 0.139 0.000
M18 Arthrosis of first carpometacarpal joint
0.860 0.140 0.000
E04 Other non-toxic goitre
0.860 0.140 0.000
E10-E14 Diabetes mellitus
0.858 0.142 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.857 0.143 0.000
M45-M49 Spondylopathies
0.856 0.144 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.853 0.146 0.000
I35.0 Aortic (valve) stenosis
0.853 0.147 0.000
M23.4 Loose body in knee
0.852 0.148 0.000
J33.9 Nasal polyp, unspecified
0.852 0.148 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.849 0.151 0.000
M25.5 Pain in joint
0.844 0.156 0.000
M25.46 Effusion of joint (Lower leg)
0.841 0.159 0.000
K35-K38 Diseases of appendix
0.841 0.159 0.000
D25 Leiomyoma of uterus
0.840 0.160 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.839 0.161 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.839 0.161 0.000
I42.0 Dilated cardiomyopathy
0.836 0.164 0.000
Chapter I Certain infectious and parasitic diseases
0.835 0.165 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.833 0.167 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.833 0.167 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.832 0.168 0.000
J90-J94 Other diseases of pleura
0.832 0.168 0.000
I37 Pulmonary valve disorders
0.825 0.175 0.000
J00-J06 Acute upper respiratory infections
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.825 0.175 0.000
K05 Gingivitis and periodontal diseases
0.825 0.175 0.000
H40-H42 Glaucoma
0.822 0.178 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.821 0.179 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.820 0.180 0.000
G95 Other diseases of spinal cord
0.820 0.180 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.818 0.182 0.000
M43 Other deforming dorsopathies
0.818 0.182 0.000
M17.5 Other secondary gonarthrosis
0.817 0.183 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.815 0.185 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.814 0.186 0.000
M17.3 Other posttraumatic gonarthrosis
0.813 0.187 0.000
G20-G26 Extrapyramidal and movement disorders
0.809 0.190 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.809 0.191 0.000
M19.0 Primary arthrosis of other joints
0.809 0.191 0.000
E50-E64 Other nutritional deficiencies
0.809 0.191 0.000
D25.9 Leiomyoma of uterus, unspecified
0.809 0.191 0.000
Q61 Cystic kidney disease
0.808 0.192 0.000
J09-J18 Influenza and pneumonia
0.806 0.194 0.000
J32 Chronic sinusitis
0.804 0.196 0.000
M25.8 Other specified joint disorders
0.804 0.196 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.803 0.197 0.000
K74 Fibrosis and cirrhosis of liver
0.803 0.197 0.000
D12.0 Caecum
0.802 0.198 0.000
I05-I09 Chronic rheumatic heart diseases
0.801 0.199 0.000
E11 Non-insulin-dependent diabetes mellitus
0.801 0.199 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.801 0.199 0.000
I47 Paroxysmal tachycardia
0.801 0.199 0.000
G90 Disorders of autonomic nervous system
0.799 0.201 0.000
M80-M85 Disorders of bone density and structure
0.798 0.202 0.000
E03.8 Other specified hypothyroidism
0.798 0.202 0.000
I35.1 Aortic (valve) insufficiency
0.798 0.202 0.000
I31.9 Disease of pericardium, unspecified
0.795 0.205 0.000
S20-S29 Injuries to the thorax
0.793 0.207 0.000
K75 Other inflammatory liver diseases
0.793 0.207 0.000
K76.6 Portal hypertension
0.792 0.208 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.791 0.208 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.791 0.209 0.000
K13 Other diseases of lip and oral mucosa
0.791 0.209 0.000
I31.3 Pericardial effusion (noninflammatory)
0.789 0.211 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.789 0.211 0.000
K91.4 Colostomy and enterostomy malfunction
0.788 0.212 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.787 0.213 0.000
K14.9 Disease of tongue, unspecified
0.785 0.215 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.785 0.215 0.000
M54.5 Low back pain
0.784 0.216 0.000
M05-M14 Inflammatory polyarthropathies
0.782 0.218 0.000
T92 Sequelae of injuries of upper limb
0.781 0.219 0.000
Chapter XXI Factors influencing health status and contact with health services
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.777 0.223 0.000
M17.0 Primary gonarthrosis, bilateral
0.776 0.224 0.000
J40 Bronchitis, not specified as acute or chronic
0.773 0.227 0.000
M25.51 Pain in joint (Shoulder region)
0.772 0.228 0.000
K14.8 Other diseases of tongue
0.771 0.229 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.771 0.229 0.000
D18 Haemangioma and lymphangioma, any site
0.769 0.231 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.768 0.232 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
Q00-Q07 Congenital malformations of the nervous system
0.766 0.234 0.000
K90 Intestinal malabsorption
0.765 0.235 0.000
G93.3 Postviral fatigue syndrome
0.765 0.235 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.761 0.239 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.761 0.239 0.000
M24 Other specific joint derangements
0.761 0.239 0.000
G96 Other disorders of central nervous system
0.760 0.240 0.000
H30-H36 Disorders of choroid and retina
0.757 0.243 0.000
I46.9 Cardiac arrest, unspecified
0.757 0.243 0.000
M22.4 Chondromalacia patellae
0.756 0.244 0.000
M43.1 Spondylolisthesis
0.755 0.245 0.000
K70.9 Alcoholic liver disease, unspecified
0.755 0.245 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.754 0.245 0.000
F17.2 Dependence syndrome
0.754 0.246 0.000
I49 Other cardiac arrhythmias
0.754 0.246 0.000
M23.49 Loose body in knee-Unspec lig/men
0.754 0.246 0.000
H40 Glaucoma
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
M25.0 Haemarthrosis
0.751 0.249 0.000
M47 Spondylosis
0.751 0.249 0.000
T18 Foreign body in alimentary tract
0.750 0.250 0.000
M25.7 Osteophyte
0.750 0.250 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.749 0.251 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.749 0.251 0.000
S50-S59 Injuries to the elbow and forearm
0.749 0.251 0.000
M86-M90 Other osteopathies
0.748 0.252 0.000
K76.8 Other specified diseases of liver
0.748 0.252 0.000
M22.8 Other disorders of patella
0.748 0.252 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.253 0.000
E11.9 Without complications
0.746 0.254 0.000
M31 Other necrotising vasculopathies
0.746 0.254 0.000
K35 Acute appendicitis
0.745 0.255 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.742 0.257 0.000
J36 Peritonsillar abscess
0.738 0.262 0.000
Q80-Q89 Other congenital malformations
0.737 0.263 0.000
M50 Cervical disk disorders
0.735 0.265 0.000
K26 Duodenal ulcer
0.734 0.266 0.000
I35.8 Other aortic valve disorders
0.734 0.266 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.734 0.266 0.000
K14.0 Glossitis
0.732 0.268 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.732 0.268 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.732 0.268 0.000
D12.2 Ascending colon
0.731 0.269 0.000
G70-G73 Diseases of myoneural junction and muscle
0.731 0.269 0.000
K72 Hepatic failure, not elsewhere classified
0.731 0.269 0.000
I60-I69 Cerebrovascular diseases
0.729 0.271 0.000
M19.94 Arthrosis, unspecified (Hand)
0.728 0.272 0.000
G61 Inflammatory polyneuropathy
0.727 0.273 0.000
Q61.3 Polycystic kidney, unspecified
0.727 0.273 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
C60-C63 Malignant neoplasms of male genital organs
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.722 0.278 0.000
I45 Other conduction disorders
0.722 0.278 0.000
I42.9 Cardiomyopathy, unspecified
0.722 0.278 0.000
J38.3 Other diseases of vocal cords
0.722 0.278 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.722 0.278 0.000
E04.2 Non-toxic multinodular goitre
0.722 0.278 0.000
I44 Atrioventricular and left bundle-branch block
0.721 0.279 0.000
M91-M94 Chondropathies
0.721 0.279 0.000
K30 Dyspepsia
0.720 0.280 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.720 0.280 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.720 0.280 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.719 0.280 0.000
M34.1 CR(E)ST syndrome
0.719 0.281 0.000
M34.9 Systemic sclerosis, unspecified
0.718 0.282 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.718 0.282 0.000
I47.1 Supraventricular tachycardia
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M15 Polyarthrosis
0.717 0.283 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.717 0.283 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
J00 Acute nasopharyngitis [common cold]
0.713 0.287 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.713 0.287 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.713 0.287 0.000
G25 Other extrapyramidal and movement disorders
0.713 0.287 0.000
M25.47 Effusion of joint (Ankle and foot)
0.712 0.288 0.000
J38.0 Paralysis of vocal cords and larynx
0.711 0.289 0.000
K07 Dentofacial anomalies [including malocclusion]
0.711 0.289 0.000
M22.2 Patellofemoral disorders
0.710 0.290 0.000
J33.0 Polyp of nasal cavity
0.710 0.290 0.000
M23.9 Internal derangement of knee, unspecified
0.709 0.290 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.709 0.290 0.000
M23.1 Discoid meniscus (congenital)
0.709 0.290 0.000
M23.0 Cystic meniscus
0.709 0.290 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.709 0.291 0.000
M48 Other spondylopathies
0.708 0.292 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.708 0.292 0.000
M54.57 Low back pain (Lumbosacral region)
0.708 0.292 0.000
J90 Pleural effusion, not elsewhere classified
0.708 0.292 0.000
M41 Scoliosis
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.707 0.293 0.000
K77 Liver disorders in diseases classified elsewhere
0.707 0.293 0.000
K73 Chronic hepatitis, not elsewhere classified
0.707 0.293 0.000
K71 Toxic liver disease
0.707 0.293 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.706 0.294 0.000
E00 Congenital iodine-deficiency syndrome
0.706 0.294 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.706 0.294 0.000
C34 Malignant neoplasm of bronchus and lung
0.705 0.295 0.000
Chapter XX External causes of morbidity and mortality
0.705 0.295 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.704 0.296 0.000
I46.0 Cardiac arrest with successful resuscitation
0.704 0.296 0.000
Q50-Q56 Congenital malformations of genital organs
0.704 0.296 0.000
M19.1 Posttraumatic arthrosis of other joints
0.703 0.297 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
M25.9 Joint disorder, unspecified
0.703 0.297 0.000
M25.3 Other instability of joint
0.703 0.297 0.000
M25.2 Flail joint
0.703 0.297 0.000
M25.1 Fistula of joint
0.703 0.297 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.702 0.298 0.000
B35-B49 Mycoses
0.702 0.298 0.000
E06 Thyroiditis
0.701 0.298 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.701 0.299 0.000
F80-F89 Disorders of psychological development
0.701 0.299 0.000
J95-J99 Other diseases of the respiratory system
0.700 0.299 0.000
I37.1 Pulmonary valve insufficiency
0.700 0.300 0.000
D34 Benign neoplasm of thyroid gland
0.700 0.300 0.000
M65-M68 Disorders of synovium and tendon
0.700 0.300 0.000
E03.5 Myxoedema coma
0.700 0.300 0.000
E03.4 Atrophy of thyroid (acquired)
0.700 0.300 0.000
E03.3 Postinfectious hypothyroidism
0.700 0.300 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.700 0.300 0.000
E03.1 Congenital hypothyroidism without goitre
0.700 0.300 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.700 0.300 0.000
M62 Other disorders of muscle
0.700 0.300 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
J37 Chronic laryngitis and laryngotracheitis
0.697 0.302 0.000
J46 Status asthmaticus
0.697 0.303 0.000
J34 Other disorders of nose and nasal sinuses
0.697 0.303 0.000
C64-C68 Malignant neoplasms of urinary tract
0.696 0.303 0.000
M23.5 Chronic instability of knee
0.696 0.304 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.696 0.304 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.696 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.696 0.304 0.000
E67 Other hyperalimentation
0.695 0.305 0.000
E68 Sequelae of hyperalimentation
0.695 0.305 0.000
E65 Localised adiposity
0.695 0.305 0.000
M70-M79 Other soft tissue disorders
0.695 0.305 0.000
I35.9 Aortic valve disorder, unspecified
0.695 0.305 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.695 0.305 0.000
E40-E46 Malnutrition
0.693 0.306 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.693 0.307 0.000
G93.4 Encephalopathy, unspecified
0.693 0.307 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.693 0.307 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.693 0.307 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.693 0.307 0.000
G92 Toxic encephalopathy
0.693 0.307 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.693 0.307 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.693 0.307 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.308 0.000
F70-F79 Mental retardation
0.692 0.308 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.692 0.308 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.309 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
T92.1 Sequelae of fracture of arm
0.690 0.310 0.000
T18.1 Foreign body in oesophagus
0.690 0.310 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.689 0.311 0.000
I05 Rheumatic mitral valve diseases
0.687 0.313 0.000
Z01.8 Other specified special examinations
0.687 0.313 0.000
H18 Other disorders of cornea
0.686 0.314 0.000
J43 Emphysema
0.686 0.314 0.000
E66.9 Obesity, unspecified
0.686 0.314 0.000
D18.0 Haemangioma, any site
0.686 0.314 0.000
J38.7 Other diseases of larynx
0.685 0.315 0.000
J91 Pleural effusion in conditions classified elsewhere
0.685 0.315 0.000
J32.9 Chronic sinusitis, unspecified
0.685 0.315 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.685 0.315 0.000
I69 Sequelae of cerebrovascular disease
0.685 0.315 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.684 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.684 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.684 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.684 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.684 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.684 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.684 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.684 0.315 0.000
I99 Other and unspecified disorders of circulatory system
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.683 0.316 0.000
T33-T35 Frostbite
0.683 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.683 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.683 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.683 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.683 0.316 0.000
H55-H59 Other disorders of eye and adnexa
0.683 0.317 0.000
E55 Vitamin D deficiency
0.683 0.317 0.000
G93.2 Benign intracranial hypertension
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.682 0.318 0.000
K05.6 Periodontal disease, unspecified
0.682 0.318 0.000
H40.0 Glaucoma suspect
0.681 0.319 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.681 0.319 0.000
E66.1 Drug-induced obesity
0.681 0.319 0.000
E66.0 Obesity due to excess calories
0.681 0.319 0.000
M54.4 Lumbago with sciatica
0.681 0.319 0.000
K76.7 Hepatorenal syndrome
0.681 0.319 0.000
K76.5 Hepatic veno-occlusive disease
0.681 0.319 0.000
K76.4 Peliosis hepatis
0.681 0.319 0.000
K76.3 Infarction of liver
0.681 0.319 0.000
K76.2 Central haemorrhagic necrosis of liver
0.681 0.319 0.000
K76.1 Chronic passive congestion of liver
0.681 0.319 0.000
D10 Benign neoplasm of mouth and pharynx
0.680 0.320 0.000
M19.8 Other specified arthrosis
0.680 0.320 0.000
M19.2 Other secondary arthrosis
0.680 0.320 0.000
D25.1 Intramural leiomyoma of uterus
0.679 0.321 0.000
F17.9 Unspecified mental and behavioural disorder
0.679 0.321 0.000
F17.8 Other mental and behavioural disorders
0.679 0.321 0.000
F17.7 Residual and late-onset psychotic disorder
0.679 0.321 0.000
F17.6 Amnesic syndrome
0.679 0.321 0.000
F17.5 Psychotic disorder
0.679 0.321 0.000
F17.4 Withdrawal state with delirium
0.679 0.321 0.000
F17.3 Withdrawal state
0.679 0.321 0.000
F17.0 Acute intoxication
0.679 0.321 0.000
Z72 Problems related to lifestyle
0.679 0.321 0.000
M54.9 Dorsalgia, unspecified
0.678 0.322 0.000
K05.1 Chronic gingivitis
0.678 0.322 0.000
S40-S49 Injuries to the shoulder and upper arm
0.675 0.325 0.000
G91 Hydrocephalus
0.675 0.325 0.000
E04.1 Non-toxic single thyroid nodule
0.675 0.325 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.674 0.326 0.000
Chapter VIII Diseases of the ear and mastoid process
0.673 0.327 0.000
K31 Other diseases of stomach and duodenum
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
Q61.2 Polycystic kidney, adult type
0.672 0.328 0.000
A00-A09 Intestinal infectious diseases
0.671 0.329 0.000
G95.8 Other specified diseases of spinal cord
0.670 0.330 0.000
S20 Superficial injury of thorax
0.670 0.330 0.000
Q12 Congenital lens malformations
0.668 0.332 0.000
G30-G32 Other degenerative diseases of the nervous system
0.667 0.332 0.000
K10 Other diseases of jaws
0.667 0.333 0.000
K09 Cysts of oral region, not elsewhere classified
0.667 0.333 0.000
K03 Other diseases of hard tissues of teeth
0.667 0.333 0.000
K00 Disorders of tooth development and eruption
0.667 0.333 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.667 0.333 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.666 0.334 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.665 0.335 0.000
H40.9 Glaucoma, unspecified
0.665 0.335 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.663 0.337 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.663 0.337 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.663 0.337 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.662 0.338 0.000
K76.9 Liver disease, unspecified
0.662 0.338 0.000
M53 Other dorsopathies, not elsewhere classified
0.661 0.339 0.000
J60-J70 Lung diseases due to external agents
0.660 0.340 0.000
G95.2 Cord compression, unspecified
0.659 0.341 0.000
I07 Rheumatic tricuspid valve diseases
0.659 0.341 0.000
I42.8 Other cardiomyopathies
0.658 0.342 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.658 0.342 0.000
I42.6 Alcoholic cardiomyopathy
0.658 0.342 0.000
I42.5 Other restrictive cardiomyopathy
0.658 0.342 0.000
I42.4 Endocardial fibroelastosis
0.658 0.342 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.658 0.342 0.000
I31.8 Other specified diseases of pericardium
0.657 0.343 0.000
I31.2 Haemopericardium, not elsewhere classified
0.657 0.343 0.000
I31.1 Chronic constrictive pericarditis
0.657 0.343 0.000
I31.0 Chronic adhesive pericarditis
0.657 0.343 0.000
K70.3 Alcoholic cirrhosis of liver
0.655 0.345 0.000
I27 Other pulmonary heart diseases
0.654 0.345 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.654 0.346 0.000
K38 Other diseases of appendix
0.654 0.346 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.654 0.346 0.000
M35.8 Other specified systemic involvement of connective tissue
0.654 0.346 0.000
M35.7 Hypermobility syndrome
0.654 0.346 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.654 0.346 0.000
M35.5 Multifocal fibrosclerosis
0.654 0.346 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.654 0.346 0.000
M35.2 Behcet's disease
0.654 0.346 0.000
M35.1 Other overlap syndromes
0.654 0.346 0.000
D11 Benign neoplasm of major salivary glands
0.654 0.346 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.653 0.347 0.000
G93.8 Other specified disorders of brain
0.653 0.347 0.000
H35 Other retinal disorders
0.653 0.347 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.347 0.000
J33.1 Polypoid sinus degeneration
0.652 0.348 0.000
M25.49 Effusion of joint (Site unspecified)
0.651 0.348 0.000
M25.48 Effusion of joint (Other)
0.651 0.348 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.651 0.348 0.000
M25.44 Effusion of joint (Hand)
0.651 0.348 0.000
M25.43 Effusion of joint (Forearm)
0.651 0.348 0.000
M25.42 Effusion of joint (Upper arm)
0.651 0.348 0.000
M25.41 Effusion of joint (Shoulder region)
0.651 0.348 0.000
M25.40 Effusion of joint (Multiple sites)
0.651 0.348 0.000
E04.9 Non-toxic goitre, unspecified
0.651 0.348 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.651 0.348 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.651 0.349 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.651 0.349 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.651 0.349 0.000
J31.0 Chronic rhinitis
0.650 0.350 0.000
M42 Spinal osteochondrosis
0.649 0.351 0.000
M40 Kyphosis and lordosis
0.649 0.351 0.000
K26.7 Chronic without haemorrhage or perforation
0.649 0.351 0.000
J33.8 Other polyp of sinus
0.649 0.351 0.000
C91 Lymphoid leukaemia
0.648 0.351 0.000
I33 Acute and subacute endocarditis
0.648 0.352 0.000
M22.1 Recurrent subluxation of patella
0.648 0.352 0.000
M22.9 Disorder of patella, unspecified
0.648 0.352 0.000
M22.3 Other derangements of patella
0.648 0.352 0.000
M22.0 Recurrent dislocation of patella
0.648 0.352 0.000
M23.37 Other meniscus derangements-Capsular lig
0.648 0.352 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.648 0.352 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.648 0.352 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.648 0.352 0.000
J39 Other diseases of upper respiratory tract
0.647 0.353 0.000
K35.3 Acute appendicitis with localized peritonitis
0.646 0.354 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.646 0.354 0.000
M54.1 Radiculopathy
0.646 0.354 0.000
E61 Deficiency of other nutrient elements
0.643 0.356 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.643 0.357 0.000
K91.5 Postcholecystectomy syndrome
0.643 0.357 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.643 0.357 0.000
K91.1 Postgastric surgery syndromes
0.643 0.357 0.000
D26 Other benign neoplasms of uterus
0.642 0.358 0.000
E16 Other disorders of pancreatic internal secretion
0.642 0.358 0.000
I42.2 Other hypertrophic cardiomyopathy
0.642 0.358 0.000
J10 Influenza due to identified influenza virus
0.642 0.358 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.642 0.358 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.641 0.359 0.000
M25.52 Pain in joint (Upper arm)
0.641 0.359 0.000
M54.6 Pain in thoracic spine
0.640 0.360 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.640 0.360 0.000
D23 Other benign neoplasms of skin
0.640 0.360 0.000
G06.0 Intracranial abscess and granuloma
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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