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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76966743
log Bayes Factor = 8.02239
Chromosome 4   position 138,144,790  (GRCh37) Explore rs76966743 on Ensembl!
Variant rs76966743 is part of Cluster X0162

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
E65-E68 Obesity and other hyperalimentation
0.995 0.005 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
E66 Obesity
0.991 0.009 0.000
F10.0 Acute intoxication
0.985 0.015 0.000
F10.2 Dependence syndrome
0.984 0.016 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.981 0.019 0.000
E66.9 Obesity, unspecified
0.980 0.020 0.000
M25 Other joint disorders, not elsewhere classified
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.960 0.040 0.000
M25.7 Osteophyte
0.958 0.042 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.947 0.053 0.000
H52 Disorders of refraction and accommodation
0.943 0.057 0.000
E10-E14 Diabetes mellitus
0.932 0.068 0.000
S00-S09 Injuries to the head
0.931 0.069 0.000
M25.76 Osteophyte (Lower leg)
0.930 0.070 0.000
M65-M68 Disorders of synovium and tendon
0.921 0.079 0.000
E20-E35 Disorders of other endocrine glands
0.919 0.081 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.918 0.082 0.000
E66.8 Other obesity
0.916 0.084 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.915 0.085 0.000
M31 Other necrotising vasculopathies
0.914 0.086 0.000
E10 Insulin-dependent diabetes mellitus
0.913 0.087 0.000
Chapter XI Diseases of the digestive system
0.910 0.090 0.000
F10.3 Withdrawal state
0.906 0.094 0.000
M50-M54 Other dorsopathies
0.900 0.100 0.000
M25.77 Osteophyte (Ankle and foot)
0.900 0.100 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.899 0.101 0.000
H52.1 Myopia
0.896 0.104 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.108 0.000
S01 Open wound of head
0.885 0.115 0.000
K70-K77 Diseases of liver
0.883 0.117 0.000
K83 Other diseases of biliary tract
0.879 0.121 0.000
S40-S49 Injuries to the shoulder and upper arm
0.879 0.121 0.000
E10.9 Without complications
0.878 0.122 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
K83.1 Obstruction of bile duct
0.874 0.126 0.000
M40-M43 Deforming dorsopathies
0.857 0.143 0.000
Y52 Agents primarily affecting the cardiovascular system
0.849 0.151 0.000
M05-M14 Inflammatory polyarthropathies
0.848 0.152 0.000
K70 Alcoholic liver disease
0.845 0.155 0.000
M31.6 Other giant cell arteritis
0.845 0.155 0.000
E10.1 With ketoacidosis
0.842 0.158 0.000
H50 Other strabismus
0.842 0.158 0.000
M51 Other intervertebral disk disorders
0.841 0.159 0.000
S10-S19 Injuries to the neck
0.837 0.163 0.000
H02 Other disorders of eyelid
0.831 0.169 0.000
Chapter XIV Diseases of the genitourinary system
0.826 0.174 0.000
F10.1 Harmful use
0.824 0.176 0.000
M25.72 Osteophyte (Upper arm)
0.823 0.177 0.000
T79-T79 Certain early complications of trauma
0.819 0.181 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.819 0.181 0.000
M60-M63 Disorders of muscles
0.817 0.183 0.000
M65 Synovitis and tenosynovitis
0.816 0.184 0.000
M86-M90 Other osteopathies
0.816 0.184 0.000
H49 Paralytic strabismus
0.814 0.186 0.000
S60-S69 Injuries to the wrist and hand
0.811 0.189 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.807 0.193 0.000
S01.5 Open wound of lip and oral cavity
0.805 0.195 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.805 0.195 0.000
H10-H13 Disorders of conjunctiva
0.803 0.197 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.801 0.199 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.799 0.201 0.000
M91-M94 Chondropathies
0.797 0.203 0.000
W50-W64 Exposure to animate mechanical forces
0.797 0.203 0.000
H52.2 Astigmatism
0.796 0.204 0.000
E23 Hypofunction and other disorders of pituitary gland
0.795 0.205 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.795 0.205 0.000
F99-F99 Unspecified mental disorder
0.794 0.206 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.794 0.206 0.000
M33 Dermatopolymyositis
0.792 0.208 0.000
N00-N08 Glomerular diseases
0.792 0.208 0.000
H02.3 Blepharochalasis
0.792 0.208 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.790 0.210 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.790 0.210 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.788 0.212 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.788 0.212 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.784 0.216 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.784 0.216 0.000
M25.9 Joint disorder, unspecified
0.784 0.216 0.000
M10 Gout
0.783 0.217 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.783 0.217 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.783 0.217 0.000
Chapter I Certain infectious and parasitic diseases
0.782 0.218 0.000
K90-K93 Other diseases of the digestive system
0.782 0.218 0.000
M23 Internal derangement of knee
0.779 0.221 0.000
E40-E46 Malnutrition
0.778 0.222 0.000
K86 Other diseases of pancreas
0.777 0.223 0.000
E65 Localised adiposity
0.774 0.225 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.774 0.226 0.000
M51.2 Other specified intervertebral disk displacement
0.769 0.231 0.000
E50-E64 Other nutritional deficiencies
0.767 0.233 0.000
M67 Other disorders of synovium and tendon
0.766 0.234 0.000
H04 Disorders of lachrymal system
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.764 0.236 0.000
M25.5 Pain in joint
0.763 0.237 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.763 0.237 0.000
H02.8 Other specified disorders of eyelid
0.762 0.238 0.000
K70.9 Alcoholic liver disease, unspecified
0.761 0.238 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.760 0.240 0.000
S01.2 Open wound of nose
0.759 0.241 0.000
M25.3 Other instability of joint
0.759 0.241 0.000
M43 Other deforming dorsopathies
0.758 0.242 0.000
K72 Hepatic failure, not elsewhere classified
0.757 0.243 0.000
K22 Other diseases of oesophagus
0.755 0.245 0.000
F60-F69 Disorders of adult personality and behaviour
0.755 0.245 0.000
K70.0 Alcoholic fatty liver
0.754 0.246 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.753 0.247 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
Y45.0 Opioids and related analgesics
0.751 0.249 0.000
S02 Fracture of skull and facial bones
0.750 0.250 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.749 0.251 0.000
H53-H54 Visual disturbances and blindness
0.749 0.251 0.000
T93 Sequelae of injuries of lower limb
0.746 0.253 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.746 0.254 0.000
N03 Chronic nephritic syndrome
0.746 0.254 0.000
F10.4 Withdrawal state with delirium
0.745 0.255 0.000
M50 Cervical disk disorders
0.745 0.255 0.000
Q21 Congenital malformations of cardiac septa
0.744 0.256 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.743 0.257 0.000
M24 Other specific joint derangements
0.743 0.257 0.000
M25.8 Other specified joint disorders
0.743 0.257 0.000
K22.1 Ulcer of oesophagus
0.742 0.258 0.000
V01-V09 Pedestrian injured in transport accident
0.740 0.260 0.000
X50-X57 Overexertion, travel and privation
0.739 0.261 0.000
K85 Acute pancreatitis
0.739 0.261 0.000
R17 Unspecified jaundice
0.738 0.262 0.000
H05 Disorders of orbit
0.737 0.263 0.000
H46 Optic neuritis
0.737 0.263 0.000
M10.9 Gout, unspecified
0.736 0.264 0.000
V20-V29 Motorcycle rider injured in transport accident
0.734 0.266 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.728 0.271 0.000
H50.9 Strabismus, unspecified
0.728 0.272 0.000
S01.0 Open wound of scalp
0.726 0.274 0.000
N25-N29 Other disorders of kidney and ureter
0.725 0.275 0.000
M65.3 Trigger finger
0.725 0.275 0.000
F30-F39 Mood [affective] disorders
0.723 0.277 0.000
S60 Superficial injury of wrist and hand
0.723 0.277 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.722 0.278 0.000
S40 Superficial injury of shoulder and upper arm
0.722 0.278 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.720 0.280 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.716 0.284 0.000
F10.8 Other mental and behavioural disorders
0.716 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.716 0.284 0.000
F10.6 Amnesic syndrome
0.716 0.284 0.000
F10.5 Psychotic disorder
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
Chapter IX Diseases of the circulatory system
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.715 0.285 0.000
N73 Other female pelvic inflammatory diseases
0.715 0.285 0.000
N03.9 Unspecified
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
E67 Other hyperalimentation
0.713 0.287 0.000
E68 Sequelae of hyperalimentation
0.713 0.287 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.713 0.287 0.000
E21.3 Hyperparathyroidism, unspecified
0.712 0.288 0.000
S06 Intracranial injury
0.712 0.288 0.000
H02.6 Xanthelasma of eyelid
0.712 0.288 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
K90 Intestinal malabsorption
0.711 0.289 0.000
M25.57 Pain in joint (Ankle and foot)
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.710 0.290 0.000
E66.1 Drug-induced obesity
0.710 0.290 0.000
E66.0 Obesity due to excess calories
0.710 0.290 0.000
K22.2 Oesophageal obstruction
0.708 0.292 0.000
W00-W19 Falls
0.708 0.292 0.000
M31.3 Wegener's granulomatosis
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.707 0.293 0.000
E34 Other endocrine disorders
0.706 0.294 0.000
T39.1 4-Aminophenol derivatives
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.705 0.294 0.000
K82 Other diseases of gallbladder
0.705 0.295 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.705 0.295 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.704 0.295 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.704 0.296 0.000
H51 Other disorders of binocular movement
0.703 0.297 0.000
Q21.1 Atrial septal defect
0.703 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.702 0.298 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
S91 Open wound of ankle and foot
0.702 0.298 0.000
M25.2 Flail joint
0.702 0.298 0.000
M25.1 Fistula of joint
0.702 0.298 0.000
M25.0 Haemarthrosis
0.702 0.298 0.000
E10.3 With ophthalmic complications
0.700 0.300 0.000
N73.6 Female pelvic peritoneal adhesions
0.700 0.300 0.000
S69 Other and unspecified injuries of wrist and hand
0.699 0.301 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.699 0.301 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.699 0.301 0.000
R42 Dizziness and giddiness
0.698 0.302 0.000
M50.2 Other cervical disk displacement
0.697 0.303 0.000
K86.8 Other specified diseases of pancreas
0.696 0.304 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.695 0.305 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.694 0.306 0.000
M51.8 Other specified intervertebral disk disorders
0.694 0.306 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.308 0.000
K70.4 Alcoholic hepatic failure
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.688 0.312 0.000
Y10-Y34 Event of undetermined intent
0.688 0.312 0.000
Y00-Y09 Assault
0.688 0.312 0.000
X85-X99 Assault
0.688 0.312 0.000
X30-X39 Exposure to forces of nature
0.688 0.312 0.000
X10-X19 Contact with heat and hot substances
0.688 0.312 0.000
X00-X09 Exposure to smoke, fire and flames
0.688 0.312 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.688 0.312 0.000
W75-W84 Other accidental threats to breathing
0.688 0.312 0.000
W65-W74 Accidental drowning and submersion
0.688 0.312 0.000
V98-V99 Other and unspecified transport accidents
0.688 0.312 0.000
V95-V97 Air and space transport accidents
0.688 0.312 0.000
V90-V94 Water transport accidents
0.688 0.312 0.000
V70-V79 Bus occupant injured in transport accident
0.688 0.312 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.688 0.312 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.688 0.312 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.688 0.312 0.000
E27 Other disorders of adrenal gland
0.688 0.312 0.000
E24 Cushing's syndrome
0.687 0.313 0.000
M43.1 Spondylolisthesis
0.687 0.313 0.000
K30 Dyspepsia
0.687 0.313 0.000
M25.79 Osteophyte (Site unspecified)
0.687 0.313 0.000
M25.73 Osteophyte (Forearm)
0.687 0.313 0.000
M25.70 Osteophyte (Multiple sites)
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.686 0.313 0.000
M62 Other disorders of muscle
0.686 0.314 0.000
H52.0 Hypermetropia
0.686 0.314 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.686 0.314 0.000
S01.3 Open wound of ear
0.685 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.316 0.000
M66 Spontaneous rupture of synovium and tendon
0.683 0.317 0.000
E13 Other specified diabetes mellitus
0.683 0.317 0.000
K73 Chronic hepatitis, not elsewhere classified
0.682 0.318 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.681 0.319 0.000
M89 Other disorders of bone
0.681 0.319 0.000
H49.2 Sixth [abducent] nerve palsy
0.679 0.321 0.000
R30-R39 Symptoms and signs involving the urinary system
0.679 0.321 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.321 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.321 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.679 0.321 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.679 0.321 0.000
T36 Poisoning by systemic antibiotics
0.679 0.321 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.678 0.321 0.000
T92 Sequelae of injuries of upper limb
0.678 0.321 0.000
Y52.1 Calcium-channel blockers
0.677 0.323 0.000
N04 Nephrotic syndrome
0.676 0.324 0.000
H52.7 Disorder of refraction, unspecified
0.676 0.324 0.000
H52.6 Other disorders of refraction
0.676 0.324 0.000
H52.5 Disorders of accommodation
0.676 0.324 0.000
H52.4 Presbyopia
0.676 0.324 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.675 0.324 0.000
M00-M03 Infectious arthropathies
0.675 0.325 0.000
K85.9 Acute pancreatitis, unspecified
0.674 0.326 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.674 0.326 0.000
S64 Injury of nerves at wrist and hand level
0.674 0.326 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.673 0.326 0.000
E29 Testicular dysfunction
0.673 0.327 0.000
H04.1 Other disorders of lachrymal gland
0.673 0.327 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
I74 Arterial embolism and thrombosis
0.672 0.328 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.672 0.328 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.671 0.329 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.670 0.330 0.000
M23.5 Chronic instability of knee
0.669 0.331 0.000
M35 Other systemic involvement of connective tissue
0.669 0.331 0.000
V10-V19 Pedal cyclist injured in transport accident
0.669 0.331 0.000
E12 Malnutrition-related diabetes mellitus
0.668 0.332 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.668 0.332 0.000
S08 Traumatic amputation of part of head
0.668 0.332 0.000
S07 Crushing injury of head
0.668 0.332 0.000
S04 Injury of cranial nerves
0.668 0.332 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.668 0.332 0.000
Q80-Q89 Other congenital malformations
0.667 0.333 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.667 0.333 0.000
F80-F89 Disorders of psychological development
0.665 0.335 0.000
R16.1 Splenomegaly, not elsewhere classified
0.664 0.336 0.000
S19 Other and unspecified injuries of neck
0.663 0.337 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
F29 Unspecified nonorganic psychosis
0.661 0.339 0.000
M70-M79 Other soft tissue disorders
0.661 0.339 0.000
T90 Sequelae of injuries of head
0.660 0.339 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.660 0.340 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.660 0.340 0.000
H53 Visual disturbances
0.659 0.341 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.659 0.341 0.000
E32 Diseases of thymus
0.659 0.341 0.000
E31 Polyglandular dysfunction
0.659 0.341 0.000
E30 Disorders of puberty, not elsewhere classified
0.659 0.341 0.000
E25 Adrenogenital disorders
0.659 0.341 0.000
E20 Hypoparathyroidism
0.659 0.341 0.000
M65.34 Trigger finger-Hand
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.658 0.342 0.000
Y58 Bacterial vaccines
0.658 0.342 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.658 0.342 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.658 0.342 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.658 0.342 0.000
Y48 Anaesthetics and therapeutic gases
0.658 0.342 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.658 0.342 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.658 0.342 0.000
M93 Other osteochondropathies
0.658 0.342 0.000
K21 Gastro-oesophageal reflux disease
0.658 0.342 0.000
I60-I69 Cerebrovascular diseases
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
F19.1 Harmful use
0.656 0.343 0.000
R31 Unspecified haematuria
0.656 0.344 0.000
R40 Somnolence, stupor and coma
0.656 0.344 0.000
K72.0 Acute and subacute hepatic failure
0.656 0.344 0.000
R94 Abnormal results of function studies
0.656 0.344 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.656 0.344 0.000
M21 Other acquired deformities of limbs
0.656 0.344 0.000
H52.3 Anisometropia and aniseikonia
0.656 0.344 0.000
M31.9 Necrotising vasculopathy, unspecified
0.655 0.344 0.000
M31.8 Other specified necrotising vasculopathies
0.655 0.344 0.000
M31.7 Microscopic polyangiitis
0.655 0.344 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.655 0.344 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.655 0.344 0.000
M31.2 Lethal midline granuloma
0.655 0.344 0.000
M31.1 Thrombotic microangiopathy
0.655 0.344 0.000
M31.0 Hypersensitivity angiitis
0.655 0.344 0.000
K90.0 Coeliac disease
0.655 0.345 0.000
E10.8 With unspecified complications
0.655 0.345 0.000
E10.7 With multiple complications
0.655 0.345 0.000
E10.6 With other specified complications
0.655 0.345 0.000
E10.0 With coma
0.655 0.345 0.000
N76 Other inflammation of vagina and vulva
0.654 0.346 0.000
E26 Hyperaldosteronism
0.653 0.346 0.000
N10-N16 Renal tubulo-interstitial diseases
0.653 0.347 0.000
S71 Open wound of hip and thigh
0.653 0.347 0.000
M20 Acquired deformities of fingers and toes
0.653 0.347 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.653 0.347 0.000
R41.0 Disorientation, unspecified
0.653 0.347 0.000
M25.59 Pain in joint (Site unspecified)
0.651 0.349 0.000
N40-N51 Diseases of male genital organs
0.651 0.349 0.000
H49.1 Fourth [trochlear] nerve palsy
0.651 0.349 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.650 0.349 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.650 0.350 0.000
E10.2 With renal complications
0.650 0.350 0.000
Y40 Systemic antibiotics
0.650 0.350 0.000
H00 Hordeolum and chalazion
0.650 0.350 0.000
S01.9 Open wound of head, part unspecified
0.650 0.350 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.649 0.351 0.000
K65-K67 Diseases of peritoneum
0.649 0.351 0.000
M33.1 Other dermatomyositis
0.649 0.351 0.000
S10 Superficial injury of neck
0.648 0.352 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.648 0.352 0.000
S01.7 Multiple open wounds of head
0.648 0.352 0.000
F99 Mental disorder, not otherwise specified
0.647 0.353 0.000
T39.0 Salicylates
0.647 0.353 0.000
N05 Unspecified nephritic syndrome
0.647 0.353 0.000
B15-B19 Viral hepatitis
0.647 0.353 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
W20-W49 Exposure to inanimate mechanical forces
0.645 0.354 0.000
E23.2 Diabetes insipidus
0.645 0.355 0.000
M67.8 Other specified disorders of synovium and tendon
0.645 0.355 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.645 0.355 0.000
R18 Ascites
0.644 0.356 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.644 0.356 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.643 0.357 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.642 0.358 0.000
H50.0 Convergent concomitant strabismus
0.642 0.358 0.000
S20-S29 Injuries to the thorax
0.642 0.358 0.000
K74 Fibrosis and cirrhosis of liver
0.642 0.358 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.641 0.359 0.000
E10.5 With peripheral circulatory complications
0.641 0.359 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.640 0.360 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.639 0.360 0.000
E23.6 Other disorders of pituitary gland
0.639 0.361 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.639 0.361 0.000
Chapter XXII Codes for special purposes
0.638 0.362 0.000
Y44 Agents primarily affecting blood constituents
0.638 0.362 0.000
M34 Systemic sclerosis
0.638 0.362 0.000
A80-A89 Viral infections of the central nervous system
0.637 0.363 0.000
H02.2 Lagophthalmos
0.637 0.363 0.000
N25 Disorders resulting from impaired renal tubular function
0.637 0.363 0.000
S12 Fracture of neck
0.637 0.363 0.000
E55 Vitamin D deficiency
0.637 0.363 0.000
H10 Conjunctivitis
0.637 0.363 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.637 0.363 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.636 0.364 0.000
H47.1 Papilloedema, unspecified
0.636 0.364 0.000
S42 Fracture of shoulder and upper arm
0.636 0.364 0.000
S41 Open wound of shoulder and upper arm
0.635 0.365 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.635 0.365 0.000
S01.4 Open wound of cheek and temporomandibular area
0.634 0.366 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.634 0.366 0.000
K77 Liver disorders in diseases classified elsewhere
0.633 0.367 0.000
K71 Toxic liver disease
0.633 0.367 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.633 0.367 0.000
M23.0 Cystic meniscus
0.633 0.367 0.000
H25-H28 Disorders of lens
0.633 0.367 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
M07 Psoriatic and enteropathic arthropathies
0.631 0.369 0.000
K83.9 Disease of biliary tract, unspecified
0.630 0.369 0.000
K83.5 Biliary cyst
0.630 0.369 0.000
K83.4 Spasm of sphincter of Oddi
0.630 0.369 0.000
K83.3 Fistula of bile duct
0.630 0.369 0.000
K83.2 Perforation of bile duct
0.630 0.369 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.630 0.370 0.000
S48 Traumatic amputation of shoulder and upper arm
0.630 0.370 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.630 0.370 0.000
S44 Injury of nerves at shoulder and upper arm level
0.630 0.370 0.000
S47 Crushing injury of shoulder and upper arm
0.630 0.370 0.000
K31 Other diseases of stomach and duodenum
0.630 0.370 0.000
N45 Orchitis and epididymitis
0.630 0.370 0.000
T98 Sequelae of other and unspecified effects of external causes
0.630 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.630 0.370 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.630 0.370 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.630 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.629 0.370 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.629 0.371 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.627 0.373 0.000
S50-S59 Injuries to the elbow and forearm
0.626 0.374 0.000
Q00-Q07 Congenital malformations of the nervous system
0.625 0.375 0.000
I73 Other peripheral vascular diseases
0.624 0.376 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.624 0.376 0.000
A30-A49 Other bacterial diseases
0.624 0.376 0.000
M25.33 Other instability of joint (Forearm)
0.622 0.377 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.621 0.379 0.000
M51.9 Intervertebral disk disorder, unspecified
0.620 0.380 0.000
M65.8 Other synovitis and tenosynovitis
0.620 0.380 0.000
E46 Unspecified protein-energy malnutrition
0.619 0.380 0.000
S69.9 Unspecified injury of wrist and hand
0.619 0.381 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.619 0.381 0.000
K76 Other diseases of liver
0.619 0.381 0.000
H05.0 Acute inflammation of orbit
0.619 0.381 0.000
M25.52 Pain in joint (Upper arm)
0.618 0.382 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.617 0.383 0.000
M25.88 Other specified joint disorders (Other)
0.616 0.384 0.000
S02.5 Fracture of tooth
0.615 0.385 0.000
M42 Spinal osteochondrosis
0.614 0.386 0.000
M40 Kyphosis and lordosis
0.614 0.386 0.000
T66-T78 Other and unspecified effects of external causes
0.614 0.386 0.000
H11 Other disorders of conjunctiva
0.614 0.386 0.000
Y57 Other and unspecified drugs and medicaments
0.614 0.386 0.000
E21.0 Primary hyperparathyroidism
0.614 0.386 0.000
M90 Osteopathies in diseases classified elsewhere
0.613 0.387 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.613 0.387 0.000
I71 Aortic aneurysm and dissection
0.613 0.387 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.613 0.387 0.000
R15 Faecal incontinence
0.612 0.388 0.000
T40.2 Other opioids
0.611 0.389 0.000
S43.0 Dislocation of shoulder joint
0.610 0.390 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.609 0.391 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.608 0.391 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.608 0.391 0.000
Y52.7 Peripheral vasodilators
0.608 0.391 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.608 0.391 0.000
H53.8 Other visual disturbances
0.608 0.392 0.000
S70 Superficial injury of hip and thigh
0.608 0.392 0.000
M14 Arthropathies in other diseases classified elsewhere
0.608 0.392 0.000
M12 Other specific arthropathies
0.608 0.392 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.608 0.392 0.000
M08 Juvenile arthritis
0.608 0.392 0.000
T40.4 Other synthetic narcotics
0.608 0.392 0.000
O85-O92 Complications predominantly related to the puerperium
0.608 0.392 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.608 0.392 0.000
M41 Scoliosis
0.606 0.394 0.000
M24.2 Disorder of ligament
0.606 0.394 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.606 0.394 0.000
K91.4 Colostomy and enterostomy malfunction
0.606 0.394 0.000
M53 Other dorsopathies, not elsewhere classified
0.606 0.394 0.000
R94.3 Abnormal results of cardiovascular function studies
0.606 0.394 0.000
K86.3 Pseudocyst of pancreas
0.606 0.394 0.000
E28 Ovarian dysfunction
0.605 0.395 0.000
H50.8 Other specified strabismus
0.604 0.396 0.000
H50.6 Mechanical strabismus
0.604 0.396 0.000
H50.5 Heterophoria
0.604 0.396 0.000
H50.4 Other and unspecified heterotropia
0.604 0.396 0.000
H50.3 Intermittent heterotropia
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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