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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77135516
log Bayes Factor = 13.8756
Chromosome 1   position 229,994,958  (GRCh37) Explore rs77135516 on Ensembl!
Variant rs77135516 is part of Cluster X0163

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M47 Spondylosis
0.999 0.001 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
Chapter VIII Diseases of the ear and mastoid process
0.996 0.004 0.000
H25-H28 Disorders of lens
0.995 0.005 0.000
M47.9 Spondylosis, unspecified
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
M40-M43 Deforming dorsopathies
0.991 0.009 0.000
K60 Fissure and fistula of anal and rectal regions
0.989 0.011 0.000
M51 Other intervertebral disk disorders
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.976 0.024 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.974 0.026 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.974 0.026 0.000
K70-K77 Diseases of liver
0.973 0.027 0.000
T81 Complications of procedures, not elsewhere classified
0.972 0.028 0.000
M47.8 Other spondylosis
0.969 0.031 0.000
H25 Senile cataract
0.966 0.034 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.963 0.037 0.000
H26 Other cataract
0.962 0.038 0.000
M51.2 Other specified intervertebral disk displacement
0.959 0.041 0.000
M41 Scoliosis
0.958 0.042 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.957 0.043 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.956 0.044 0.000
H65-H75 Diseases of middle ear and mastoid
0.950 0.050 0.000
H90-H95 Other disorders of ear
0.948 0.052 0.000
H25.0 Senile incipient cataract
0.945 0.055 0.000
K50-K52 Noninfective enteritis and colitis
0.944 0.056 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.943 0.057 0.000
K63 Other diseases of intestine
0.941 0.059 0.000
K70 Alcoholic liver disease
0.941 0.059 0.000
H26.9 Cataract, unspecified
0.940 0.060 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.935 0.065 0.000
M54 Dorsalgia
0.935 0.065 0.000
M41.9 Scoliosis, unspecified
0.934 0.066 0.000
M47.86 Other spondylosis (Lumbar region)
0.934 0.066 0.000
F30-F39 Mood [affective] disorders
0.934 0.066 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.934 0.066 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.933 0.067 0.000
H53-H54 Visual disturbances and blindness
0.930 0.070 0.000
K82 Other diseases of gallbladder
0.923 0.077 0.000
K63.3 Ulcer of intestine
0.919 0.081 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.918 0.082 0.000
K60.2 Anal fissure, unspecified
0.914 0.086 0.000
N40-N51 Diseases of male genital organs
0.914 0.086 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.913 0.087 0.000
H43-H45 Disorders of vitreous body and globe
0.907 0.093 0.000
V10-V19 Pedal cyclist injured in transport accident
0.904 0.096 0.000
Chapter XIV Diseases of the genitourinary system
0.903 0.097 0.000
M43 Other deforming dorsopathies
0.902 0.098 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.902 0.098 0.000
H60-H62 Diseases of external ear
0.901 0.099 0.000
K50 Crohn's disease [regional enteritis]
0.901 0.099 0.000
K63.9 Disease of intestine, unspecified
0.896 0.104 0.000
N41 Inflammatory diseases of prostate
0.896 0.104 0.000
H65 Nonsuppurative otitis media
0.891 0.109 0.000
Y83.6 Removal of other organ (partial) (total)
0.891 0.109 0.000
N48 Other disorders of penis
0.891 0.109 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.889 0.111 0.000
K60.1 Chronic anal fissure
0.888 0.112 0.000
K61 Abscess of anal and rectal regions
0.883 0.117 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.882 0.118 0.000
K81 Cholecystitis
0.882 0.118 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.881 0.119 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.875 0.125 0.000
K82.8 Other specified diseases of gallbladder
0.870 0.130 0.000
Y83.8 Other surgical procedures
0.868 0.132 0.000
K80 Cholelithiasis
0.867 0.133 0.000
H53 Visual disturbances
0.867 0.133 0.000
F60-F69 Disorders of adult personality and behaviour
0.867 0.133 0.000
K56.1 Intussusception
0.864 0.136 0.000
M54.5 Low back pain
0.862 0.138 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.862 0.138 0.000
H40-H42 Glaucoma
0.861 0.139 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.861 0.139 0.000
K60.0 Acute anal fissure
0.860 0.140 0.000
K50.9 Crohn's disease, unspecified
0.857 0.143 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.857 0.143 0.000
K70.1 Alcoholic hepatitis
0.857 0.143 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.850 0.150 0.000
K60.5 Anorectal fistula
0.846 0.154 0.000
N41.1 Chronic prostatitis
0.845 0.155 0.000
H91 Other hearing loss
0.843 0.157 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.842 0.158 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.835 0.165 0.000
M65-M68 Disorders of synovium and tendon
0.835 0.165 0.000
M54.1 Radiculopathy
0.834 0.166 0.000
F31 Bipolar affective disorder
0.834 0.166 0.000
F32 Depressive episode
0.829 0.171 0.000
K51 Ulcerative colitis
0.828 0.172 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.828 0.172 0.000
M54.59 Low back pain (Site unspecified)
0.827 0.173 0.000
H61 Other disorders of external ear
0.826 0.174 0.000
M47.89 Other spondylosis (Site unspecified)
0.826 0.174 0.000
T86 Failure and rejection of transplanted organs and tissues
0.825 0.175 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.824 0.176 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.824 0.176 0.000
M51.8 Other specified intervertebral disk disorders
0.822 0.178 0.000
H52 Disorders of refraction and accommodation
0.821 0.179 0.000
Q80-Q89 Other congenital malformations
0.820 0.180 0.000
H50 Other strabismus
0.817 0.183 0.000
H43 Disorders of vitreous body
0.817 0.183 0.000
M45 Ankylosing spondylitis
0.816 0.184 0.000
Chapter X Diseases of the respiratory system
0.816 0.184 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.816 0.184 0.000
M54.2 Cervicalgia
0.815 0.185 0.000
K74 Fibrosis and cirrhosis of liver
0.815 0.185 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.814 0.186 0.000
M43.0 Spondylolysis
0.813 0.187 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.812 0.188 0.000
K70.4 Alcoholic hepatic failure
0.812 0.188 0.000
F41 Other anxiety disorders
0.811 0.189 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.811 0.189 0.000
M40 Kyphosis and lordosis
0.811 0.189 0.000
Y83.3 Surgical operation with formation of external stoma
0.808 0.192 0.000
N42 Other disorders of prostate
0.807 0.193 0.000
W00-W19 Falls
0.806 0.194 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.806 0.194 0.000
N48.4 Impotence of organic origin
0.804 0.196 0.000
K81.1 Chronic cholecystitis
0.803 0.197 0.000
Chapter XXI Factors influencing health status and contact with health services
0.801 0.199 0.000
V18.0 Driver injured in nontraffic accident
0.801 0.199 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.801 0.199 0.000
S00-S09 Injuries to the head
0.801 0.199 0.000
S10-S19 Injuries to the neck
0.798 0.202 0.000
M46 Other inflammatory spondylopathies
0.797 0.203 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.797 0.203 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.797 0.203 0.000
H92 Otalgia and effusion of ear
0.795 0.205 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.795 0.205 0.000
K76 Other diseases of liver
0.792 0.208 0.000
K59 Other functional intestinal disorders
0.792 0.208 0.000
H74 Other disorders of middle ear and mastoid
0.789 0.211 0.000
H21 Other disorders of iris and ciliary body
0.788 0.212 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.786 0.213 0.000
H53.1 Subjective visual disturbances
0.786 0.214 0.000
F60 Specific personality disorders
0.786 0.214 0.000
H01 Other inflammation of eyelid
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
Z73 Problems related to life-management difficulty
0.781 0.219 0.000
N00-N08 Glomerular diseases
0.780 0.220 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.779 0.221 0.000
N40 Hyperplasia of prostate
0.778 0.222 0.000
N48.6 Balanitis xerotica obliterans
0.777 0.223 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.777 0.223 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.776 0.224 0.000
F41.9 Anxiety disorder, unspecified
0.776 0.224 0.000
K60.4 Rectal fistula
0.776 0.224 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.775 0.225 0.000
K61.3 Ischiorectal abscess
0.773 0.227 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.772 0.228 0.000
K56.7 Ileus, unspecified
0.770 0.230 0.000
H91.9 Hearing loss, unspecified
0.768 0.232 0.000
K70.9 Alcoholic liver disease, unspecified
0.767 0.233 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.766 0.234 0.000
H25.1 Senile nuclear cataract
0.765 0.235 0.000
M47.1 Other spondylosis with myelopathy
0.765 0.235 0.000
N42.9 Disorder of prostate, unspecified
0.764 0.236 0.000
Y00-Y09 Assault
0.763 0.237 0.000
H43.8 Other disorders of vitreous body
0.763 0.237 0.000
H40 Glaucoma
0.762 0.238 0.000
H72 Perforation of tympanic membrane
0.762 0.238 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
H61.0 Perichondritis of external ear
0.759 0.241 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.759 0.241 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.758 0.242 0.000
F31.9 Bipolar affective disorder, unspecified
0.757 0.243 0.000
M20-M25 Other joint disorders
0.755 0.245 0.000
M54.12 Radiculopathy (Cervical region)
0.753 0.247 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.749 0.251 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
K90-K93 Other diseases of the digestive system
0.745 0.255 0.000
M53 Other dorsopathies, not elsewhere classified
0.745 0.255 0.000
H26.4 After-cataract
0.744 0.256 0.000
H50.0 Convergent concomitant strabismus
0.741 0.259 0.000
T87 Complications peculiar to reattachment and amputation
0.739 0.261 0.000
K51.4 Pseudopolyposis of colon
0.739 0.261 0.000
N48.5 Ulcer of penis
0.737 0.263 0.000
M50 Cervical disk disorders
0.737 0.263 0.000
N48.8 Other specified disorders of penis
0.736 0.264 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.736 0.264 0.000
H26.2 Complicated cataract
0.735 0.265 0.000
H69 Other disorders of Eustachian tube
0.735 0.265 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.734 0.266 0.000
K50.1 Crohn's disease of large intestine
0.734 0.266 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.731 0.269 0.000
M23 Internal derangement of knee
0.728 0.272 0.000
H16 Keratitis
0.728 0.272 0.000
Y88 Sequelae of surgical and medical care as external cause
0.727 0.273 0.000
M43.02 Spondylolysis (Cervical region)
0.726 0.274 0.000
T91 Sequelae of injuries of neck and trunk
0.726 0.274 0.000
F39 Unspecified mood [affective] disorder
0.724 0.276 0.000
Y86 Sequelae of other accidents
0.724 0.276 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.724 0.276 0.000
H54 Blindness and low vision
0.723 0.277 0.000
H18 Other disorders of cornea
0.723 0.277 0.000
H00 Hordeolum and chalazion
0.722 0.278 0.000
H65.2 Chronic serous otitis media
0.722 0.278 0.000
F43 Reaction to severe stress, and adjustment disorders
0.721 0.279 0.000
M43.1 Spondylolisthesis
0.720 0.280 0.000
M54.22 Cervicalgia (Cervical region)
0.719 0.281 0.000
H44 Disorders of globe
0.719 0.281 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.719 0.281 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
F30 Manic episode
0.717 0.282 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
H01.0 Blepharitis
0.717 0.283 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.716 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.716 0.284 0.000
J20-J22 Other acute lower respiratory infections
0.715 0.285 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.713 0.287 0.000
K76.9 Liver disease, unspecified
0.713 0.287 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.713 0.287 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.713 0.287 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.713 0.287 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.713 0.287 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.713 0.287 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.712 0.287 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
M42 Spinal osteochondrosis
0.710 0.290 0.000
N41.0 Acute prostatitis
0.709 0.291 0.000
N17-N19 Renal failure
0.709 0.291 0.000
Y83.5 Amputation of limb(s)
0.708 0.292 0.000
K82.9 Disease of gallbladder, unspecified
0.707 0.293 0.000
N48.1 Balanoposthitis
0.705 0.295 0.000
H53.8 Other visual disturbances
0.705 0.295 0.000
H20 Iridocyclitis
0.704 0.296 0.000
M51.3 Other specified intervertebral disk degeneration
0.703 0.297 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.703 0.297 0.000
M51.4 Schmorl's nodes
0.703 0.297 0.000
K70.3 Alcoholic cirrhosis of liver
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.297 0.000
F70-F79 Mental retardation
0.702 0.297 0.000
H53.0 Amblyopia ex anopsia
0.701 0.299 0.000
H70 Mastoiditis and related conditions
0.700 0.300 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.700 0.300 0.000
F32.0 Mild depressive episode
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
H90 Conductive and sensorineural hearing loss
0.700 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.699 0.301 0.000
T90 Sequelae of injuries of head
0.699 0.301 0.000
K56.3 Gallstone ileus
0.698 0.301 0.000
K56.0 Paralytic ileus
0.698 0.301 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.698 0.302 0.000
K77 Liver disorders in diseases classified elsewhere
0.698 0.302 0.000
K71 Toxic liver disease
0.698 0.302 0.000
M48 Other spondylopathies
0.697 0.303 0.000
H73 Other disorders of tympanic membrane
0.697 0.303 0.000
K61.0 Anal abscess
0.697 0.303 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.697 0.303 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.697 0.303 0.000
N42.0 Calculus of prostate
0.696 0.304 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.694 0.305 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.694 0.305 0.000
M47.84 Other spondylosis (Thoracic region)
0.694 0.305 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.694 0.305 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.694 0.305 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.694 0.305 0.000
K82.4 Cholesterolosis of gallbladder
0.694 0.306 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.694 0.306 0.000
H25.2 Senile cataract, morgagnian type
0.693 0.307 0.000
M86-M90 Other osteopathies
0.692 0.308 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.692 0.308 0.000
K81.0 Acute cholecystitis
0.691 0.309 0.000
K72 Hepatic failure, not elsewhere classified
0.691 0.309 0.000
H26.3 Drug-induced cataract
0.690 0.310 0.000
H26.0 Infantile, juvenile and presenile cataract
0.690 0.310 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.689 0.311 0.000
H52.1 Myopia
0.689 0.311 0.000
Y95 Nosocomial condition
0.689 0.311 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.689 0.311 0.000
K70.0 Alcoholic fatty liver
0.688 0.312 0.000
H27 Other disorders of lens
0.688 0.312 0.000
Q85 Phakomatoses, not elsewhere classified
0.687 0.313 0.000
Z60 Problems related to social environment
0.687 0.313 0.000
Z71.3 Dietary counselling and surveillance
0.687 0.313 0.000
M41.8 Other forms of scoliosis
0.686 0.313 0.000
M41.5 Other secondary scoliosis
0.686 0.313 0.000
M41.4 Neuromuscular scoliosis
0.686 0.313 0.000
M41.3 Thoracogenic scoliosis
0.686 0.313 0.000
M41.2 Other idiopathic scoliosis
0.686 0.313 0.000
M41.1 Juvenile idiopathic scoliosis
0.686 0.313 0.000
M41.0 Infantile idiopathic scoliosis
0.686 0.313 0.000
Z71.8 Other specified counselling
0.687 0.313 0.000
M80-M85 Disorders of bone density and structure
0.687 0.313 0.000
J09-J18 Influenza and pneumonia
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
S31 Open wound of abdomen, lower back and pelvis
0.684 0.316 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.683 0.317 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.683 0.317 0.000
K73 Chronic hepatitis, not elsewhere classified
0.683 0.317 0.000
M47.2 Other spondylosis with radiculopathy
0.681 0.318 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.681 0.318 0.000
H68 Eustachian salpingitis and obstruction
0.681 0.318 0.000
H67 Otitis media in diseases classified elsewhere
0.681 0.318 0.000
Y83.4 Other reconstructive surgery
0.681 0.319 0.000
T93 Sequelae of injuries of lower limb
0.681 0.319 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.679 0.321 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.679 0.321 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.678 0.322 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.678 0.322 0.000
T17 Foreign body in respiratory tract
0.677 0.323 0.000
K82.1 Hydrops of gallbladder
0.676 0.324 0.000
K63.4 Enteroptosis
0.675 0.325 0.000
K63.0 Abscess of intestine
0.675 0.325 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.675 0.325 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.675 0.325 0.000
M65 Synovitis and tenosynovitis
0.674 0.326 0.000
H40.2 Primary angle-closure glaucoma
0.674 0.326 0.000
H25.8 Other senile cataract
0.673 0.326 0.000
H49 Paralytic strabismus
0.673 0.327 0.000
M70-M79 Other soft tissue disorders
0.673 0.327 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.673 0.327 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.673 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
T36 Poisoning by systemic antibiotics
0.673 0.327 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.673 0.327 0.000
N25-N29 Other disorders of kidney and ureter
0.672 0.328 0.000
K80.4 Calculus of bile duct with cholecystitis
0.672 0.328 0.000
H52.2 Astigmatism
0.671 0.329 0.000
H95.1 Other disorders following mastoidectomy
0.671 0.329 0.000
H60 Otitis externa
0.671 0.329 0.000
F32.8 Other depressive episodes
0.671 0.329 0.000
K59.9 Functional intestinal disorder, unspecified
0.670 0.330 0.000
K59.3 Megacolon, not elsewhere classified
0.670 0.330 0.000
N02 Recurrent and persistent haematuria
0.670 0.330 0.000
M54.8 Other dorsalgia
0.670 0.330 0.000
M54.0 Panniculitis affecting regions of neck and back
0.670 0.330 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.670 0.330 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.670 0.330 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.670 0.330 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.670 0.330 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.670 0.330 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.670 0.330 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.670 0.330 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.670 0.330 0.000
F38 Other mood [affective] disorders
0.669 0.331 0.000
F34 Persistent mood [affective] disorders
0.669 0.331 0.000
H92.1 Otorrhoea
0.669 0.331 0.000
H51 Other disorders of binocular movement
0.669 0.331 0.000
W07 Fall involving chair
0.668 0.331 0.000
Z74 Problems related to care-provider dependency
0.668 0.332 0.000
H93 Other disorders of ear, not elsewhere classified
0.668 0.332 0.000
H65.4 Other chronic nonsuppurative otitis media
0.667 0.333 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
K74.5 Biliary cirrhosis, unspecified
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.666 0.334 0.000
K56.4 Other impaction of intestine
0.665 0.335 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.665 0.335 0.000
H10-H13 Disorders of conjunctiva
0.664 0.336 0.000
M67 Other disorders of synovium and tendon
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.664 0.336 0.000
N99-N99 Other disorders of the genitourinary system
0.663 0.337 0.000
T81.9 Unspecified complication of procedure
0.662 0.338 0.000
K82.3 Fistula of gallbladder
0.662 0.338 0.000
K82.2 Perforation of gallbladder
0.662 0.338 0.000
K82.0 Obstruction of gallbladder
0.662 0.338 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.662 0.338 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.662 0.338 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.661 0.339 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.658 0.342 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.658 0.342 0.000
H17 Corneal scars and opacities
0.658 0.342 0.000
H15 Disorders of sclera
0.658 0.342 0.000
H54.0 Blindness, both eyes
0.658 0.342 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.657 0.343 0.000
Z60.2 Living alone
0.656 0.344 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.655 0.345 0.000
N46 Male infertility
0.655 0.345 0.000
N44 Torsion of testis
0.655 0.345 0.000
H53.4 Visual field defects
0.655 0.345 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.654 0.346 0.000
F32.1 Moderate depressive episode
0.654 0.346 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.653 0.346 0.000
H80-H83 Diseases of inner ear
0.653 0.346 0.000
K74.6 Other and unspecified cirrhosis of liver
0.653 0.347 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.652 0.348 0.000
M40.5 Lordosis, unspecified
0.652 0.348 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.652 0.348 0.000
H26.1 Traumatic cataract
0.652 0.348 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.651 0.349 0.000
K50.8 Other Crohn's disease
0.651 0.349 0.000
S05 Injury of eye and orbit
0.651 0.349 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.650 0.349 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.650 0.350 0.000
F60.9 Personality disorder, unspecified
0.649 0.351 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.648 0.351 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.648 0.351 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.648 0.351 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.648 0.351 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.648 0.351 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.648 0.351 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.648 0.351 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.648 0.351 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.648 0.351 0.000
R26 Abnormalities of gait and mobility
0.647 0.353 0.000
M43.9 Deforming dorsopathy, unspecified
0.647 0.353 0.000
M43.8 Other specified deforming dorsopathies
0.647 0.353 0.000
M43.6 Torticollis
0.647 0.353 0.000
M43.5 Other recurrent vertebral subluxation
0.647 0.353 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.647 0.353 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.647 0.353 0.000
M43.2 Other fusion of spine
0.647 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.647 0.353 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.647 0.353 0.000
Q82 Other congenital malformations of skin
0.647 0.353 0.000
M51.9 Intervertebral disk disorder, unspecified
0.646 0.354 0.000
M24 Other specific joint derangements
0.646 0.354 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.646 0.354 0.000
K51.8 Other ulcerative colitis
0.646 0.354 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.646 0.354 0.000
S09 Other and unspecified injuries of head
0.645 0.355 0.000
S12 Fracture of neck
0.645 0.355 0.000
N04 Nephrotic syndrome
0.645 0.355 0.000
F60.7 Dependent personality disorder
0.644 0.356 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.644 0.356 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.644 0.356 0.000
K76.8 Other specified diseases of liver
0.644 0.356 0.000
M43.06 Spondylolysis (Lumbar region)
0.643 0.357 0.000
N41.8 Other inflammatory diseases of prostate
0.642 0.357 0.000
N41.3 Prostatocystitis
0.642 0.357 0.000
N41.2 Abscess of prostate
0.642 0.357 0.000
H25.9 Senile cataract, unspecified
0.642 0.358 0.000
H53.2 Diplopia
0.642 0.358 0.000
F99-F99 Unspecified mental disorder
0.641 0.359 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.640 0.360 0.000
M23.8 Other internal derangements of knee
0.640 0.360 0.000
H65.1 Other acute nonsuppurative otitis media
0.639 0.361 0.000
H65.0 Acute serous otitis media
0.639 0.361 0.000
N48.9 Disorder of penis, unspecified
0.639 0.361 0.000
N48.3 Priapism
0.639 0.361 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.638 0.361 0.000
F60.3 Emotionally unstable personality disorder
0.638 0.362 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.638 0.362 0.000
T95 Sequelae of burns, corrosions and frostbite
0.637 0.363 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.637 0.363 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.637 0.363 0.000
H71 Cholesteatoma of middle ear
0.637 0.363 0.000
W08 Fall involving other furniture
0.636 0.364 0.000
F01 Vascular dementia
0.636 0.364 0.000
H61.2 Impacted cerumen
0.636 0.364 0.000
Z76 Persons encountering health services in other circumstances
0.636 0.364 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.635 0.365 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.635 0.365 0.000
S80-S89 Injuries to the knee and lower leg
0.635 0.365 0.000
H21.0 Hyphaema
0.634 0.366 0.000
H21.8 Other specified disorders of iris and ciliary body
0.634 0.366 0.000
K61.4 Intrasphincteric abscess
0.633 0.367 0.000
K61.2 Anorectal abscess
0.633 0.367 0.000
K61.1 Rectal abscess
0.633 0.367 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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