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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77145174
log Bayes Factor = 21.2117
Chromosome 15   position 57,177,676  (GRCh37) Explore rs77145174 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N40 Hyperplasia of prostate
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E11.9 Without complications
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.993 0.007 0.000
R30-R39 Symptoms and signs involving the urinary system
0.992 0.008 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.987 0.013 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
N17-N19 Renal failure
0.986 0.014 0.000
J30-J39 Other diseases of upper respiratory tract
0.985 0.015 0.000
R39 Other symptoms and signs involving the urinary system
0.984 0.016 0.000
R79 Other abnormal findings of blood chemistry
0.982 0.018 0.000
M20-M25 Other joint disorders
0.980 0.020 0.000
N17 Acute renal failure
0.977 0.023 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.975 0.025 0.000
J40-J47 Chronic lower respiratory diseases
0.975 0.025 0.000
R06 Abnormalities of breathing
0.974 0.026 0.000
M46 Other inflammatory spondylopathies
0.972 0.028 0.000
Chapter II Neoplasms
0.971 0.029 0.000
N17.9 Acute renal failure, unspecified
0.971 0.029 0.000
I20-I25 Ischaemic heart diseases
0.971 0.029 0.000
D10-D36 Benign neoplasms
0.970 0.030 0.000
R06.0 Dyspnoea
0.969 0.031 0.000
J44 Other chronic obstructive pulmonary disease
0.969 0.031 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.966 0.034 0.000
R07 Pain in throat and chest
0.965 0.035 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.964 0.036 0.000
R07.2 Precordial pain
0.961 0.039 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.959 0.041 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
I20 Angina pectoris
0.957 0.043 0.000
J34 Other disorders of nose and nasal sinuses
0.955 0.045 0.000
M70-M79 Other soft tissue disorders
0.942 0.058 0.000
R35 Polyuria
0.933 0.067 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.930 0.070 0.000
M25 Other joint disorders, not elsewhere classified
0.930 0.070 0.000
J00-J06 Acute upper respiratory infections
0.927 0.073 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.927 0.073 0.000
I20.9 Angina pectoris, unspecified
0.922 0.078 0.000
E14 Unspecified diabetes mellitus
0.920 0.080 0.000
M75 Shoulder lesions
0.920 0.080 0.000
F41 Other anxiety disorders
0.912 0.088 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.911 0.089 0.000
Chapter VII Diseases of the eye and adnexa
0.911 0.089 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.910 0.090 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.908 0.092 0.000
R50-R69 General symptoms and signs
0.903 0.097 0.000
J34.3 Hypertrophy of nasal turbinates
0.903 0.097 0.000
D22 Melanocytic naevi
0.902 0.098 0.000
R39.1 Other difficulties with micturition
0.901 0.099 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.898 0.102 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.896 0.104 0.000
F43 Reaction to severe stress, and adjustment disorders
0.896 0.104 0.000
I67 Other cerebrovascular diseases
0.895 0.105 0.000
R63 Symptoms and signs concerning food and fluid intake
0.895 0.105 0.000
D34 Benign neoplasm of thyroid gland
0.892 0.108 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.889 0.111 0.000
R63.4 Abnormal weight loss
0.888 0.112 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.886 0.114 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.886 0.114 0.000
G20-G26 Extrapyramidal and movement disorders
0.885 0.115 0.000
E14.9 Without complications
0.885 0.115 0.000
D11 Benign neoplasm of major salivary glands
0.882 0.118 0.000
M25.5 Pain in joint
0.881 0.119 0.000
E20-E35 Disorders of other endocrine glands
0.880 0.120 0.000
I20.8 Other forms of angina pectoris
0.879 0.121 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.879 0.121 0.000
R01 Cardiac murmurs and other cardiac sounds
0.876 0.124 0.000
M23 Internal derangement of knee
0.875 0.125 0.000
M75.3 Calcific tendinitis of shoulder
0.874 0.126 0.000
I60 Subarachnoid haemorrhage
0.873 0.127 0.000
J47 Bronchiectasis
0.872 0.128 0.000
J30 Vasomotor and allergic rhinitis
0.869 0.131 0.000
E65-E68 Obesity and other hyperalimentation
0.866 0.134 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.865 0.135 0.000
M80-M85 Disorders of bone density and structure
0.864 0.136 0.000
H43-H45 Disorders of vitreous body and globe
0.863 0.137 0.000
M24 Other specific joint derangements
0.862 0.138 0.000
R50 Fever of unknown origin
0.862 0.138 0.000
M40-M43 Deforming dorsopathies
0.861 0.139 0.000
J35 Chronic diseases of tonsils and adenoids
0.860 0.140 0.000
J02 Acute pharyngitis
0.858 0.142 0.000
I63 Cerebral infarction
0.858 0.142 0.000
G30-G32 Other degenerative diseases of the nervous system
0.857 0.143 0.000
F41.2 Mixed anxiety and depressive disorder
0.856 0.144 0.000
C51-C58 Malignant neoplasms of female genital organs
0.855 0.145 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.854 0.146 0.000
N25-N29 Other disorders of kidney and ureter
0.854 0.146 0.000
Chapter I Certain infectious and parasitic diseases
0.854 0.146 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.853 0.147 0.000
M23.3 Other meniscus derangements
0.851 0.149 0.000
D17 Benign lipomatous neoplasm
0.851 0.149 0.000
G20 Parkinson's disease
0.848 0.152 0.000
R32 Unspecified urinary incontinence
0.846 0.154 0.000
I77 Other disorders of arteries and arterioles
0.844 0.156 0.000
N42 Other disorders of prostate
0.844 0.156 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.841 0.159 0.000
R50.9 Fever, unspecified
0.838 0.162 0.000
M25.56 Pain in joint (Lower leg)
0.836 0.164 0.000
I67.8 Other specified cerebrovascular diseases
0.834 0.166 0.000
I62 Other nontraumatic intracranial haemorrhage
0.834 0.166 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.834 0.166 0.000
D35.1 Parathyroid gland
0.832 0.168 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.831 0.169 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.831 0.169 0.000
M22 Disorders of patella
0.830 0.170 0.000
E11.1 With ketoacidosis
0.828 0.172 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.828 0.172 0.000
I24 Other acute ischaemic heart diseases
0.826 0.174 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.824 0.176 0.000
R06.4 Hyperventilation
0.822 0.178 0.000
F03 Unspecified dementia
0.822 0.178 0.000
H43 Disorders of vitreous body
0.822 0.178 0.000
N50 Other disorders of male genital organs
0.821 0.179 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.819 0.181 0.000
I27 Other pulmonary heart diseases
0.819 0.181 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.816 0.184 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.815 0.185 0.000
D32 Benign neoplasm of meninges
0.814 0.186 0.000
M75.1 Rotator cuff syndrome
0.811 0.189 0.000
E11.0 With coma
0.810 0.189 0.000
J02.9 Acute pharyngitis, unspecified
0.808 0.192 0.000
N18 Chronic renal failure
0.808 0.192 0.000
N45 Orchitis and epididymitis
0.807 0.193 0.000
N00-N08 Glomerular diseases
0.806 0.194 0.000
I20.0 Unstable angina
0.802 0.198 0.000
N48 Other disorders of penis
0.802 0.198 0.000
M45 Ankylosing spondylitis
0.800 0.200 0.000
C64-C68 Malignant neoplasms of urinary tract
0.798 0.202 0.000
D11.0 Parotid gland
0.797 0.203 0.000
N41 Inflammatory diseases of prostate
0.796 0.204 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.794 0.206 0.000
M75.4 Impingement syndrome of shoulder
0.793 0.207 0.000
J39 Other diseases of upper respiratory tract
0.793 0.207 0.000
I05-I09 Chronic rheumatic heart diseases
0.791 0.209 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.791 0.209 0.000
Chapter XX External causes of morbidity and mortality
0.791 0.209 0.000
R80 Isolated proteinuria
0.789 0.211 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.788 0.212 0.000
D22.4 Melanocytic naevi of scalp and neck
0.787 0.213 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.787 0.213 0.000
M47 Spondylosis
0.784 0.216 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.783 0.217 0.000
I61 Intracerebral haemorrhage
0.783 0.217 0.000
I63.9 Cerebral infarction, unspecified
0.782 0.218 0.000
F43.2 Adjustment disorders
0.781 0.219 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.219 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.779 0.221 0.000
R73 Elevated blood glucose level
0.777 0.223 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.776 0.224 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.775 0.225 0.000
R01.0 Benign and innocent cardiac murmurs
0.775 0.225 0.000
R45 Symptoms and signs involving emotional state
0.773 0.227 0.000
R74 Abnormal serum enzyme levels
0.771 0.229 0.000
E66 Obesity
0.770 0.230 0.000
H43.8 Other disorders of vitreous body
0.770 0.230 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.769 0.231 0.000
A30-A49 Other bacterial diseases
0.767 0.233 0.000
N43 Hydrocele and spermatocele
0.767 0.233 0.000
H10-H13 Disorders of conjunctiva
0.764 0.235 0.000
J32 Chronic sinusitis
0.764 0.236 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.763 0.237 0.000
B15-B19 Viral hepatitis
0.762 0.238 0.000
M05-M14 Inflammatory polyarthropathies
0.761 0.239 0.000
D36 Benign neoplasm of other and unspecified sites
0.761 0.239 0.000
F43.0 Acute stress reaction
0.760 0.240 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.759 0.241 0.000
M46.4 Discitis, unspecified
0.759 0.241 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.759 0.241 0.000
R71 Abnormality of red blood cells
0.759 0.241 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.757 0.243 0.000
E11.4 With neurological complications
0.757 0.243 0.000
R07.1 Chest pain on breathing
0.757 0.243 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.757 0.243 0.000
R94 Abnormal results of function studies
0.756 0.244 0.000
I74 Arterial embolism and thrombosis
0.754 0.245 0.000
M31 Other necrotising vasculopathies
0.754 0.246 0.000
I27.0 Primary pulmonary hypertension
0.754 0.246 0.000
M25.57 Pain in joint (Ankle and foot)
0.753 0.247 0.000
H55-H59 Other disorders of eye and adnexa
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.752 0.248 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.751 0.249 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.750 0.250 0.000
D35.0 Adrenal gland
0.749 0.251 0.000
G43 Migraine
0.749 0.251 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.748 0.252 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.748 0.252 0.000
I77.1 Stricture of artery
0.748 0.252 0.000
R30 Pain associated with micturition
0.748 0.252 0.000
R47-R49 Symptoms and signs involving speech and voice
0.746 0.254 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.745 0.255 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.745 0.255 0.000
N99-N99 Other disorders of the genitourinary system
0.744 0.255 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.744 0.256 0.000
E13 Other specified diabetes mellitus
0.744 0.256 0.000
M85 Other disorders of bone density and structure
0.743 0.257 0.000
M91-M94 Chondropathies
0.742 0.258 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.741 0.258 0.000
F41.1 Generalised anxiety disorder
0.740 0.259 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.740 0.260 0.000
R60 Oedema, not elsewhere classified
0.738 0.262 0.000
M43 Other deforming dorsopathies
0.738 0.262 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.738 0.262 0.000
F30-F39 Mood [affective] disorders
0.738 0.262 0.000
M25.8 Other specified joint disorders
0.737 0.263 0.000
D29 Benign neoplasm of male genital organs
0.737 0.263 0.000
C71 Malignant neoplasm of brain
0.735 0.265 0.000
T79-T79 Certain early complications of trauma
0.734 0.266 0.000
M22.4 Chondromalacia patellae
0.734 0.266 0.000
M71 Other bursopathies
0.733 0.267 0.000
M86-M90 Other osteopathies
0.733 0.267 0.000
G43.9 Migraine, unspecified
0.732 0.268 0.000
J37 Chronic laryngitis and laryngotracheitis
0.731 0.269 0.000
E27 Other disorders of adrenal gland
0.731 0.269 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.730 0.270 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.730 0.270 0.000
E11.2 With renal complications
0.729 0.270 0.000
M24.1 Other articular cartilage disorders
0.728 0.272 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.726 0.274 0.000
N18.5 Chronic kidney disease, stage 5
0.726 0.274 0.000
J35.0 Chronic tonsillitis
0.725 0.275 0.000
D24 Benign neoplasm of breast
0.724 0.276 0.000
D26 Other benign neoplasms of uterus
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.722 0.278 0.000
R63.0 Anorexia
0.722 0.278 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.722 0.278 0.000
M47.2 Other spondylosis with radiculopathy
0.721 0.278 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.721 0.279 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.721 0.279 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.282 0.000
J30.4 Allergic rhinitis, unspecified
0.718 0.282 0.000
I71 Aortic aneurysm and dissection
0.718 0.282 0.000
N42.2 Atrophy of prostate
0.718 0.282 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.718 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.717 0.283 0.000
N46 Male infertility
0.717 0.283 0.000
N44 Torsion of testis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
E11.8 With unspecified complications
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
C67 Malignant neoplasm of bladder
0.716 0.284 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.715 0.285 0.000
M24.5 Contracture of joint
0.715 0.285 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.713 0.287 0.000
N41.0 Acute prostatitis
0.713 0.287 0.000
M25.51 Pain in joint (Shoulder region)
0.713 0.287 0.000
E50-E64 Other nutritional deficiencies
0.713 0.287 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
R36 Urethral discharge
0.711 0.289 0.000
R34 Anuria and oliguria
0.711 0.289 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.710 0.290 0.000
R77 Other abnormalities of plasma proteins
0.710 0.290 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.710 0.290 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.710 0.290 0.000
D23 Other benign neoplasms of skin
0.710 0.290 0.000
F00 Dementia in Alzheimer's disease
0.710 0.290 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.709 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.291 0.000
C53 Malignant neoplasm of cervix uteri
0.709 0.291 0.000
R41.3 Other amnesia
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.707 0.293 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.707 0.293 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
I67.2 Cerebral atherosclerosis
0.706 0.294 0.000
T90 Sequelae of injuries of head
0.706 0.294 0.000
R39.2 Extrarenal uraemia
0.705 0.294 0.000
R39.0 Extravasation of urine
0.705 0.294 0.000
M80 Osteoporosis with pathological fracture
0.705 0.295 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.705 0.295 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.705 0.295 0.000
R79.0 Abnormal level of blood mineral
0.704 0.296 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.703 0.297 0.000
C51 Malignant neoplasm of vulva
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
M32 Systemic lupus erythematosus
0.702 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.298 0.000
M25.0 Haemarthrosis
0.702 0.298 0.000
E11.3 With ophthalmic complications
0.702 0.298 0.000
N17.8 Other acute renal failure
0.701 0.299 0.000
N17.2 Acute renal failure with medullary necrosis
0.701 0.299 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.701 0.299 0.000
N17.0 Acute renal failure with tubular necrosis
0.701 0.299 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.700 0.300 0.000
D11.9 Major salivary gland, unspecified
0.700 0.300 0.000
R53 Malaise and fatigue
0.699 0.301 0.000
J60-J70 Lung diseases due to external agents
0.699 0.301 0.000
N50.8 Other specified disorders of male genital organs
0.699 0.301 0.000
J41 Simple and mucopurulent chronic bronchitis
0.699 0.301 0.000
J42 Unspecified chronic bronchitis
0.699 0.301 0.000
R06.7 Sneezing
0.699 0.301 0.000
R06.6 Hiccough
0.699 0.301 0.000
R06.3 Periodic breathing
0.699 0.301 0.000
R06.1 Stridor
0.699 0.301 0.000
J30.1 Allergic rhinitis due to pollen
0.697 0.303 0.000
M46.8 Other specified inflammatory spondylopathies
0.697 0.303 0.000
M46.5 Other infective spondylopathies
0.697 0.303 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.697 0.303 0.000
M46.2 Osteomyelitis of vertebra
0.697 0.303 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.697 0.303 0.000
M46.0 Spinal enthesopathy
0.697 0.303 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.696 0.303 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.303 0.000
I23 Certain current complications following acute myocardial infarction
0.696 0.304 0.000
D31 Benign neoplasm of eye and adnexa
0.695 0.305 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.695 0.305 0.000
D19 Benign neoplasm of mesothelial tissue
0.695 0.305 0.000
D16 Benign neoplasm of bone and articular cartilage
0.695 0.305 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.695 0.305 0.000
D30 Benign neoplasm of urinary organs
0.694 0.306 0.000
M75.2 Bicipital tendinitis
0.693 0.307 0.000
M25.52 Pain in joint (Upper arm)
0.693 0.307 0.000
F48 Other neurotic disorders
0.693 0.307 0.000
F44 Dissociative [conversion] disorders
0.693 0.307 0.000
F42 Obsessive-compulsive disorder
0.693 0.307 0.000
S60-S69 Injuries to the wrist and hand
0.692 0.308 0.000
R68 Other general symptoms and signs
0.691 0.309 0.000
E66.9 Obesity, unspecified
0.691 0.309 0.000
E29 Testicular dysfunction
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.689 0.311 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.688 0.312 0.000
F43.1 Posttraumatic stress disorder
0.688 0.312 0.000
J06.9 Acute upper respiratory infection, unspecified
0.688 0.312 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.688 0.312 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.688 0.312 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.688 0.312 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.688 0.312 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.688 0.312 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.688 0.312 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.688 0.312 0.000
R41.0 Disorientation, unspecified
0.686 0.314 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.686 0.314 0.000
M84 Disorders of continuity of bone
0.685 0.314 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.685 0.315 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.684 0.316 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.684 0.316 0.000
N48.8 Other specified disorders of penis
0.684 0.316 0.000
E40-E46 Malnutrition
0.683 0.317 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.683 0.317 0.000
N04 Nephrotic syndrome
0.683 0.317 0.000
R01.1 Cardiac murmur, unspecified
0.682 0.318 0.000
R94.5 Abnormal results of liver function studies
0.681 0.319 0.000
E20 Hypoparathyroidism
0.681 0.319 0.000
J84 Other interstitial pulmonary diseases
0.679 0.321 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.679 0.321 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.679 0.321 0.000
J04 Acute laryngitis and tracheitis
0.678 0.322 0.000
E34 Other endocrine disorders
0.678 0.322 0.000
F99-F99 Unspecified mental disorder
0.678 0.322 0.000
C54 Malignant neoplasm of corpus uteri
0.677 0.323 0.000
M76 Enthesopathies of lower limb, excluding foot
0.676 0.324 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.676 0.324 0.000
Chapter XXII Codes for special purposes
0.675 0.325 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.675 0.325 0.000
D22.0 Melanocytic naevi of lip
0.675 0.325 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.675 0.325 0.000
J30.3 Other allergic rhinitis
0.674 0.326 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.674 0.326 0.000
M25.3 Other instability of joint
0.672 0.328 0.000
H02 Other disorders of eyelid
0.672 0.328 0.000
R06.5 Mouth breathing
0.672 0.328 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.671 0.329 0.000
A40 Streptococcal septicaemia
0.671 0.329 0.000
M23.9 Internal derangement of knee, unspecified
0.669 0.331 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.669 0.331 0.000
D35.2 Pituitary gland
0.668 0.332 0.000
M25.9 Joint disorder, unspecified
0.667 0.333 0.000
M25.2 Flail joint
0.667 0.333 0.000
M25.1 Fistula of joint
0.667 0.333 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.666 0.334 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.666 0.334 0.000
R46 Symptoms and signs involving appearance and behaviour
0.666 0.334 0.000
J39.8 Other specified diseases of upper respiratory tract
0.666 0.334 0.000
F40 Phobic anxiety disorders
0.665 0.334 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.665 0.335 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.665 0.335 0.000
J01 Acute sinusitis
0.665 0.335 0.000
I10-I15 Hypertensive diseases
0.665 0.335 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.665 0.335 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.664 0.336 0.000
J46 Status asthmaticus
0.663 0.337 0.000
M41 Scoliosis
0.663 0.337 0.000
F45 Somatoform disorders
0.662 0.337 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.662 0.338 0.000
H10 Conjunctivitis
0.662 0.338 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.662 0.338 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.662 0.338 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.662 0.338 0.000
R73.9 Hyperglycaemia, unspecified
0.661 0.339 0.000
Q50-Q56 Congenital malformations of genital organs
0.661 0.339 0.000
D10 Benign neoplasm of mouth and pharynx
0.660 0.340 0.000
R57 Shock, not elsewhere classified
0.660 0.340 0.000
E14.8 With unspecified complications
0.660 0.340 0.000
E14.7 With multiple complications
0.660 0.340 0.000
E14.6 With other specified complications
0.660 0.340 0.000
E14.5 With peripheral circulatory complications
0.660 0.340 0.000
E14.4 With neurological complications
0.660 0.340 0.000
E14.2 Withrenal complications
0.660 0.340 0.000
E14.1 With ketoacidosis
0.660 0.340 0.000
E14.0 With coma
0.660 0.340 0.000
N25 Disorders resulting from impaired renal tubular function
0.660 0.340 0.000
M75.8 Other shoulder lesions
0.660 0.340 0.000
M75.9 Shoulder lesion, unspecified
0.660 0.340 0.000
H44 Disorders of globe
0.659 0.340 0.000
N42.1 Congestion and haemorrhage of prostate
0.659 0.341 0.000
I27.2 Other secondary pulmonary hypertension
0.659 0.341 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.659 0.341 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.659 0.341 0.000
R45.1 Restlessness and agitation
0.658 0.342 0.000
S20-S29 Injuries to the thorax
0.658 0.342 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
I67.9 Cerebrovascular disease, unspecified
0.657 0.343 0.000
D32.0 Cerebral meninges
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.656 0.344 0.000
I05 Rheumatic mitral valve diseases
0.656 0.344 0.000
M34 Systemic sclerosis
0.655 0.344 0.000
Q21 Congenital malformations of cardiac septa
0.654 0.346 0.000
F41.8 Other specified anxiety disorders
0.654 0.346 0.000
F41.3 Other mixed anxiety disorders
0.654 0.346 0.000
C04 Malignant neoplasm of floor of mouth
0.654 0.346 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.654 0.346 0.000
H43.3 Other vitreous opacities
0.654 0.346 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.653 0.346 0.000
F02 Dementia in other diseases classified elsewhere
0.653 0.346 0.000
F09 Unspecified organic or symptomatic mental disorder
0.653 0.346 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.653 0.346 0.000
F01 Vascular dementia
0.653 0.347 0.000
I72 Other aneurysm
0.653 0.347 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.652 0.348 0.000
D35.9 Endocrine gland, unspecified
0.651 0.349 0.000
D35.8 Pluriglandular involvement
0.651 0.349 0.000
D35.7 Other specified endocrine glands
0.651 0.349 0.000
D35.6 Aortic body and other paraganglia
0.651 0.349 0.000
D35.5 Carotid body
0.651 0.349 0.000
D35.4 Pineal gland
0.651 0.349 0.000
D35.3 Craniopharyngeal duct
0.651 0.349 0.000
R58 Haemorrhage, not elsewhere classified
0.651 0.349 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.651 0.349 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.651 0.349 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.651 0.349 0.000
E27.1 Primary adrenocortical insufficiency
0.651 0.349 0.000
D32.9 Meninges, unspecified
0.650 0.350 0.000
C50-C50 Malignant neoplasm of breast
0.649 0.351 0.000
R76 Other abnormal immunological findings in serum
0.649 0.351 0.000
A49 Bacterial infection of unspecified site
0.648 0.352 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.648 0.352 0.000
R62 Lack of expected normal physiological development
0.648 0.352 0.000
R64 Cachexia
0.648 0.352 0.000
M43.1 Spondylolisthesis
0.648 0.352 0.000
D14.1 Larynx
0.647 0.353 0.000
Chapter XXI Factors influencing health status and contact with health services
0.647 0.353 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.647 0.353 0.000
D22.9 Melanocytic naevi, unspecified
0.647 0.353 0.000
L08 Other local infections of skin and subcutaneous tissue
0.647 0.353 0.000
M85.8 Other specified disorders of bone density and structure
0.647 0.353 0.000
E22 Hyperfunction of pituitary gland
0.646 0.354 0.000
R07.4 Chest pain, unspecified
0.646 0.354 0.000
M65-M68 Disorders of synovium and tendon
0.646 0.354 0.000
F20 Schizophrenia
0.646 0.354 0.000
F25 Schizoaffective disorders
0.646 0.354 0.000
Q80-Q89 Other congenital malformations
0.645 0.354 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.644 0.355 0.000
S10-S19 Injuries to the neck
0.644 0.356 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.643 0.357 0.000
R47 Speech disturbances, not elsewhere classified
0.643 0.357 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.643 0.357 0.000
F43.9 Reaction to severe stress, unspecified
0.642 0.358 0.000
F43.8 Other reactions to severe stress
0.642 0.358 0.000
M77 Other enthesopathies
0.642 0.358 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.641 0.358 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.641 0.358 0.000
I67.5 Moyamoya disease
0.641 0.358 0.000
I67.4 Hypertensive encephalopathy
0.641 0.358 0.000
I67.3 Progressive vascular leukoencephalopathy
0.641 0.358 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.641 0.358 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.641 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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