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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77572683
log Bayes Factor = 7.85519
Chromosome 12   position 114,261,767  (GRCh37) Explore rs77572683 on Ensembl!
Variant rs77572683 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
M16 Coxarthrosis [arthrosis of hip]
0.993 0.007 0.000
I51.7 Cardiomegaly
0.991 0.009 0.000
I20 Angina pectoris
0.987 0.013 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
M16.1 Other primary coxarthrosis
0.980 0.020 0.000
I73 Other peripheral vascular diseases
0.977 0.023 0.000
M25 Other joint disorders, not elsewhere classified
0.971 0.029 0.000
I51.9 Heart disease, unspecified
0.966 0.034 0.000
S00-S09 Injuries to the head
0.962 0.038 0.000
M19 Other arthrosis
0.960 0.040 0.000
Chapter VII Diseases of the eye and adnexa
0.960 0.040 0.000
I50 Heart failure
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.957 0.043 0.000
I20.8 Other forms of angina pectoris
0.951 0.049 0.000
S01 Open wound of head
0.950 0.050 0.000
W00-W19 Falls
0.946 0.054 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.944 0.056 0.000
I74 Arterial embolism and thrombosis
0.938 0.062 0.000
M19.9 Arthrosis, unspecified
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
I73.9 Peripheral vascular disease, unspecified
0.936 0.064 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.935 0.065 0.000
I42 Cardiomyopathy
0.933 0.067 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.930 0.070 0.000
M16.7 Other secondary coxarthrosis
0.930 0.070 0.000
M25.5 Pain in joint
0.924 0.076 0.000
M24 Other specific joint derangements
0.922 0.078 0.000
I21 Acute myocardial infarction
0.917 0.083 0.000
I24 Other acute ischaemic heart diseases
0.916 0.084 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.912 0.088 0.000
I50.0 Congestive heart failure
0.912 0.088 0.000
S01.8 Open wound of other parts of head
0.907 0.093 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.905 0.095 0.000
S70-S79 Injuries to the hip and thigh
0.900 0.100 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.899 0.101 0.000
G35 Multiple sclerosis
0.897 0.103 0.000
I20.9 Angina pectoris, unspecified
0.895 0.105 0.000
S32 Fracture of lumbar spine and pelvis
0.893 0.107 0.000
I21.4 Acute subendocardial myocardial infarction
0.893 0.107 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.890 0.110 0.000
M05-M14 Inflammatory polyarthropathies
0.887 0.113 0.000
B25-B34 Other viral diseases
0.879 0.121 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.879 0.121 0.000
M25.4 Effusion of joint
0.878 0.122 0.000
Chapter V Mental and behavioural disorders
0.878 0.122 0.000
I20.0 Unstable angina
0.878 0.122 0.000
S01.4 Open wound of cheek and temporomandibular area
0.877 0.123 0.000
I46 Cardiac arrest
0.875 0.125 0.000
I73.0 Raynaud's syndrome
0.874 0.126 0.000
I45 Other conduction disorders
0.872 0.128 0.000
M21 Other acquired deformities of limbs
0.871 0.129 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.869 0.131 0.000
H52 Disorders of refraction and accommodation
0.863 0.137 0.000
S90-S99 Injuries to the ankle and foot
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.862 0.138 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.861 0.139 0.000
I51.6 Cardiovascular disease, unspecified
0.861 0.139 0.000
I50.1 Left ventricular failure
0.855 0.145 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.854 0.146 0.000
I77 Other disorders of arteries and arterioles
0.853 0.147 0.000
S01.1 Open wound of eyelid and periocular area
0.852 0.148 0.000
I42.9 Cardiomyopathy, unspecified
0.851 0.149 0.000
B02 Zoster [herpes zoster]
0.849 0.151 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.849 0.151 0.000
I24.8 Other forms of acute ischaemic heart disease
0.848 0.152 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.847 0.153 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.844 0.156 0.000
I70 Atherosclerosis
0.842 0.158 0.000
S80-S89 Injuries to the knee and lower leg
0.841 0.159 0.000
F20 Schizophrenia
0.839 0.161 0.000
V40-V49 Car occupant injured in transport accident
0.838 0.162 0.000
W13 Fall from, out of or through building or structure
0.836 0.164 0.000
I21.9 Acute myocardial infarction, unspecified
0.831 0.169 0.000
M19.98 Arthrosis, unspecified (Other)
0.829 0.171 0.000
S10-S19 Injuries to the neck
0.828 0.172 0.000
M22 Disorders of patella
0.823 0.177 0.000
F20.9 Schizophrenia, unspecified
0.817 0.183 0.000
B02.9 Zoster without complication
0.814 0.186 0.000
M25.7 Osteophyte
0.813 0.187 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.811 0.189 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.810 0.190 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.809 0.191 0.000
I22 Subsequent myocardial infarction
0.807 0.193 0.000
M16.5 Other posttraumatic coxarthrosis
0.802 0.198 0.000
M18 Arthrosis of first carpometacarpal joint
0.801 0.198 0.000
S72 Fracture of femur
0.799 0.201 0.000
I46.9 Cardiac arrest, unspecified
0.799 0.201 0.000
H18 Other disorders of cornea
0.794 0.206 0.000
B34 Viral infection of unspecified site
0.793 0.207 0.000
I78 Diseases of capillaries
0.789 0.211 0.000
H52.2 Astigmatism
0.787 0.213 0.000
S92 Fracture of foot, except ankle
0.786 0.214 0.000
M25.57 Pain in joint (Ankle and foot)
0.786 0.214 0.000
H52.0 Hypermetropia
0.786 0.214 0.000
I42.8 Other cardiomyopathies
0.785 0.215 0.000
M11 Other crystal arthropathies
0.781 0.219 0.000
A80-A89 Viral infections of the central nervous system
0.778 0.222 0.000
S05 Injury of eye and orbit
0.778 0.222 0.000
M24.0 Loose body in joint
0.777 0.223 0.000
H49 Paralytic strabismus
0.776 0.224 0.000
W10 Fall on and from stairs and steps
0.775 0.225 0.000
G37 Other demyelinating diseases of central nervous system
0.775 0.225 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.774 0.226 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.770 0.230 0.000
S32.4 Fracture of acetabulum
0.768 0.232 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.763 0.237 0.000
T93 Sequelae of injuries of lower limb
0.763 0.237 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.763 0.237 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.762 0.238 0.000
W17 Other fall from one level to another
0.762 0.238 0.000
M22.4 Chondromalacia patellae
0.760 0.240 0.000
S09 Other and unspecified injuries of head
0.758 0.242 0.000
B25 Cytomegaloviral disease
0.757 0.243 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.757 0.243 0.000
W13.9 Unspecified place
0.756 0.244 0.000
I42.6 Alcoholic cardiomyopathy
0.756 0.244 0.000
T92 Sequelae of injuries of upper limb
0.756 0.244 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.755 0.245 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.754 0.246 0.000
B99-B99 Other infectious diseases
0.753 0.247 0.000
W11 Fall on and from ladder
0.750 0.250 0.000
I51.4 Myocarditis, unspecified
0.750 0.250 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.749 0.251 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
G90 Disorders of autonomic nervous system
0.748 0.252 0.000
X10-X19 Contact with heat and hot substances
0.747 0.253 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.746 0.254 0.000
I45.9 Conduction disorder, unspecified
0.744 0.256 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.744 0.256 0.000
F23 Acute and transient psychotic disorders
0.744 0.256 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
M24.2 Disorder of ligament
0.741 0.259 0.000
I71 Aortic aneurysm and dissection
0.741 0.259 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.741 0.259 0.000
S32.5 Fracture of pubis
0.740 0.260 0.000
M25.9 Joint disorder, unspecified
0.740 0.260 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.739 0.261 0.000
S01.3 Open wound of ear
0.739 0.261 0.000
I45.6 Preexcitation syndrome
0.738 0.262 0.000
M16.3 Other dysplastic coxarthrosis
0.737 0.263 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.737 0.263 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.736 0.264 0.000
M10 Gout
0.736 0.264 0.000
I38 Endocarditis, valve unspecified
0.736 0.264 0.000
W07 Fall involving chair
0.735 0.265 0.000
G96 Other disorders of central nervous system
0.734 0.265 0.000
W18 Other fall on same level
0.733 0.267 0.000
G70-G73 Diseases of myoneural junction and muscle
0.733 0.267 0.000
M21.6 Other acquired deformities of ankle and foot
0.732 0.268 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.732 0.268 0.000
G93 Other disorders of brain
0.731 0.269 0.000
F80-F89 Disorders of psychological development
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.269 0.000
M00-M03 Infectious arthropathies
0.730 0.270 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.270 0.000
H46 Optic neuritis
0.728 0.271 0.000
S37 Injury of urinary and pelvic organs
0.728 0.272 0.000
S01.5 Open wound of lip and oral cavity
0.728 0.272 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.726 0.273 0.000
M19.94 Arthrosis, unspecified (Hand)
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.274 0.000
M25.42 Effusion of joint (Upper arm)
0.725 0.275 0.000
B34.9 Viral infection, unspecified
0.725 0.275 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.725 0.275 0.000
I34 Nonrheumatic mitral valve disorders
0.724 0.276 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.724 0.276 0.000
V80-V89 Other land transport accidents
0.724 0.276 0.000
I72 Other aneurysm
0.721 0.279 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.721 0.279 0.000
S31 Open wound of abdomen, lower back and pelvis
0.721 0.279 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.720 0.280 0.000
M25.0 Haemarthrosis
0.719 0.280 0.000
M13 Other arthritis
0.719 0.281 0.000
W50-W64 Exposure to animate mechanical forces
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H20 Iridocyclitis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I51.5 Myocardial degeneration
0.716 0.283 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.716 0.283 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.716 0.283 0.000
I51.0 Cardiac septal defect, acquired
0.716 0.283 0.000
M15 Polyarthrosis
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
G20-G26 Extrapyramidal and movement disorders
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.286 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.712 0.288 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.712 0.288 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.712 0.288 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.712 0.288 0.000
M16.9 Coxarthrosis, unspecified
0.710 0.290 0.000
S32.1 Fracture of sacrum
0.710 0.290 0.000
M19.1 Posttraumatic arthrosis of other joints
0.710 0.290 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.710 0.290 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
H01 Other inflammation of eyelid
0.708 0.292 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
M11.2 Other chondrocalcinosis
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
G12 Spinal muscular atrophy and related syndromes
0.705 0.295 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
M24.1 Other articular cartilage disorders
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.702 0.298 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.702 0.298 0.000
S02 Fracture of skull and facial bones
0.702 0.298 0.000
M34 Systemic sclerosis
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
I73.8 Other specified peripheral vascular diseases
0.701 0.299 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.701 0.299 0.000
M50-M54 Other dorsopathies
0.700 0.300 0.000
I05-I09 Chronic rheumatic heart diseases
0.699 0.301 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.699 0.301 0.000
B02.2 Zoster with other nervous system involvement
0.698 0.302 0.000
W19 Unspecified fall
0.698 0.302 0.000
M21.1 Varus deformity, not elsewhere classified
0.697 0.303 0.000
M25.2 Flail joint
0.696 0.304 0.000
M25.1 Fistula of joint
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.695 0.305 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.695 0.305 0.000
S92.0 Fracture of calcaneus
0.694 0.306 0.000
B00 Herpesviral [herpes simplex] infections
0.693 0.307 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
Y43 Primarily systemic agents
0.691 0.309 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
S08 Traumatic amputation of part of head
0.690 0.310 0.000
S07 Crushing injury of head
0.690 0.310 0.000
S04 Injury of cranial nerves
0.690 0.310 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.310 0.000
S86 Injury of muscle and tendon at lower leg level
0.689 0.311 0.000
H52.7 Disorder of refraction, unspecified
0.689 0.311 0.000
M19.8 Other specified arthrosis
0.688 0.312 0.000
M19.2 Other secondary arthrosis
0.688 0.312 0.000
H55-H59 Other disorders of eye and adnexa
0.686 0.314 0.000
M25.3 Other instability of joint
0.686 0.314 0.000
M40-M43 Deforming dorsopathies
0.686 0.314 0.000
T91 Sequelae of injuries of neck and trunk
0.685 0.315 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.684 0.315 0.000
M31 Other necrotising vasculopathies
0.684 0.316 0.000
H00 Hordeolum and chalazion
0.684 0.316 0.000
M21.4 Flat foot [pes planus] (acquired)
0.683 0.317 0.000
S82 Fracture of lower leg, including ankle
0.683 0.317 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
I70.0 Atherosclerosis of aorta
0.683 0.317 0.000
H16 Keratitis
0.681 0.319 0.000
S32.40 Fracture of acetabulum (closed)
0.679 0.321 0.000
S12 Fracture of neck
0.679 0.321 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.679 0.321 0.000
W15 Fall from cliff
0.679 0.321 0.000
W14 Fall from tree
0.679 0.321 0.000
W12 Fall on and from scaffolding
0.679 0.321 0.000
W09 Fall involving playground equipment
0.679 0.321 0.000
W05 Fall involving wheelchair
0.679 0.321 0.000
W04 Fall while being carried or supported by other persons
0.679 0.321 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.679 0.321 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.679 0.321 0.000
W00 Fall on same level involving ice and snow
0.679 0.321 0.000
H49.2 Sixth [abducent] nerve palsy
0.679 0.321 0.000
S72.0 Fracture of neck of femur
0.677 0.323 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.677 0.323 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.677 0.323 0.000
S36 Injury of intra-abdominal organs
0.677 0.323 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.677 0.323 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.677 0.323 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.677 0.323 0.000
S70 Superficial injury of hip and thigh
0.676 0.324 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.324 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.675 0.325 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.673 0.327 0.000
I74.8 Embolism and thrombosis of other arteries
0.673 0.327 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.673 0.327 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.673 0.327 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.673 0.327 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
I74.5 Embolism and thrombosis of iliac artery
0.671 0.329 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
S79 Other and unspecified injuries of hip and thigh
0.670 0.329 0.000
M25.46 Effusion of joint (Lower leg)
0.670 0.329 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.670 0.330 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.670 0.330 0.000
B25.9 Cytomegaloviral disease, unspecified
0.670 0.330 0.000
M17 Gonarthrosis [arthrosis of knee]
0.669 0.331 0.000
D55-D59 Haemolytic anaemias
0.669 0.331 0.000
S32.3 Fracture of ilium
0.669 0.331 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.669 0.331 0.000
I42.5 Other restrictive cardiomyopathy
0.669 0.331 0.000
I42.4 Endocardial fibroelastosis
0.669 0.331 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.669 0.331 0.000
S01.7 Multiple open wounds of head
0.668 0.332 0.000
G36 Other acute disseminated demyelination
0.667 0.333 0.000
T94.1 Sequelae of injuries, not specified by body region
0.666 0.334 0.000
F20.0 Paranoid schizophrenia
0.666 0.334 0.000
S20-S29 Injuries to the thorax
0.666 0.334 0.000
I77.0 Arteriovenous fistula, acquired
0.664 0.336 0.000
M25.77 Osteophyte (Ankle and foot)
0.664 0.336 0.000
I45.3 Trifascicular block
0.663 0.337 0.000
M91-M94 Chondropathies
0.663 0.337 0.000
M25.58 Pain in joint (Other)
0.663 0.337 0.000
M24.9 Joint derangement, unspecified
0.661 0.339 0.000
M24.7 Protrusio acetabuli
0.661 0.339 0.000
M24.6 Ankylosis of joint
0.661 0.339 0.000
M24.5 Contracture of joint
0.661 0.339 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.661 0.339 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.661 0.339 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.339 0.000
W06 Fall involving bed
0.661 0.339 0.000
M25.56 Pain in joint (Lower leg)
0.660 0.340 0.000
M25.50 Pain in joint (Multiple sites)
0.660 0.340 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.659 0.341 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.659 0.341 0.000
H21 Other disorders of iris and ciliary body
0.659 0.341 0.000
I77.8 Other specified disorders of arteries and arterioles
0.659 0.341 0.000
M50 Cervical disk disorders
0.659 0.341 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.659 0.341 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.657 0.342 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.657 0.342 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.657 0.343 0.000
I24.1 Dressler's syndrome
0.657 0.343 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.656 0.344 0.000
D68 Other coagulation defects
0.655 0.345 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.654 0.346 0.000
H18.8 Other specified disorders of cornea
0.653 0.347 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.652 0.348 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.652 0.348 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.651 0.349 0.000
I30 Acute pericarditis
0.650 0.349 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.650 0.349 0.000
H05 Disorders of orbit
0.650 0.350 0.000
W10.4 Street and highway
0.650 0.350 0.000
A87 Viral meningitis
0.650 0.350 0.000
H51 Other disorders of binocular movement
0.649 0.351 0.000
A00-A09 Intestinal infectious diseases
0.649 0.351 0.000
M21.0 Valgus deformity, not elsewhere classified
0.648 0.351 0.000
W08 Fall involving other furniture
0.648 0.352 0.000
I77.1 Stricture of artery
0.647 0.353 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.647 0.353 0.000
S78 Traumatic amputation of hip and thigh
0.645 0.355 0.000
S77 Crushing injury of hip and thigh
0.645 0.355 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.645 0.355 0.000
S75 Injury of blood vessels at hip and thigh level
0.645 0.355 0.000
S74 Injury of nerves at hip and thigh level
0.645 0.355 0.000
T95 Sequelae of burns, corrosions and frostbite
0.645 0.355 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.645 0.355 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.645 0.355 0.000
S72.1 Pertrochanteric fracture
0.645 0.355 0.000
I31 Other diseases of pericardium
0.643 0.356 0.000
M24.02 Loose body in joint (Upper arm)
0.643 0.357 0.000
M25.72 Osteophyte (Upper arm)
0.643 0.357 0.000
G96.0 Cerebrospinal fluid leak
0.643 0.357 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.642 0.357 0.000
F60-F69 Disorders of adult personality and behaviour
0.642 0.358 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.641 0.359 0.000
I51.8 Other ill-defined heart diseases
0.640 0.360 0.000
S01.0 Open wound of scalp
0.640 0.360 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.640 0.360 0.000
S32.2 Fracture of coccyx
0.640 0.360 0.000
M25.47 Effusion of joint (Ankle and foot)
0.640 0.360 0.000
M17.0 Primary gonarthrosis, bilateral
0.640 0.360 0.000
S91 Open wound of ankle and foot
0.639 0.361 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.639 0.361 0.000
D60-D64 Aplastic and other anaemias
0.639 0.361 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.638 0.362 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.638 0.362 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.638 0.362 0.000
H17 Corneal scars and opacities
0.638 0.362 0.000
H15 Disorders of sclera
0.638 0.362 0.000
S09.8 Other specified injuries of head
0.638 0.362 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.637 0.363 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.637 0.363 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.637 0.363 0.000
M50.1 Cervical disk disorder with radiculopathy
0.636 0.364 0.000
M14 Arthropathies in other diseases classified elsewhere
0.636 0.364 0.000
M12 Other specific arthropathies
0.636 0.364 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.636 0.364 0.000
M08 Juvenile arthritis
0.636 0.364 0.000
F25 Schizoaffective disorders
0.636 0.364 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.635 0.365 0.000
H18.5 Hereditary corneal dystrophies
0.635 0.365 0.000
I78.1 Naevus, nonneoplastic
0.634 0.366 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.634 0.366 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.633 0.367 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.632 0.368 0.000
S14 Injury of nerves and spinal cord at neck level
0.632 0.368 0.000
I42.2 Other hypertrophic cardiomyopathy
0.631 0.369 0.000
S32.50 Fracture of pubis (closed)
0.631 0.369 0.000
B33 Other viral diseases, not elsewhere classified
0.630 0.370 0.000
B30 Viral conjunctivitis
0.630 0.370 0.000
B27 Infectious mononucleosis
0.630 0.370 0.000
B26 Mumps
0.630 0.370 0.000
B06 Rubella [German measles]
0.630 0.370 0.000
B05 Measles
0.630 0.370 0.000
B01 Varicella [chickenpox]
0.630 0.370 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.630 0.370 0.000
B04 Monkeypox
0.630 0.370 0.000
B03 Smallpox
0.630 0.370 0.000
M25.49 Effusion of joint (Site unspecified)
0.630 0.370 0.000
M25.48 Effusion of joint (Other)
0.630 0.370 0.000
M25.44 Effusion of joint (Hand)
0.630 0.370 0.000
M25.43 Effusion of joint (Forearm)
0.630 0.370 0.000
M25.41 Effusion of joint (Shoulder region)
0.630 0.370 0.000
M25.40 Effusion of joint (Multiple sites)
0.630 0.370 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.630 0.370 0.000
F70-F79 Mental retardation
0.630 0.370 0.000
W17.4 Street and highway
0.630 0.370 0.000
G12.2 Motor neuron disease
0.630 0.370 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.629 0.371 0.000
M80-M85 Disorders of bone density and structure
0.628 0.371 0.000
S92.00 Fracture of calcaneus (closed)
0.628 0.372 0.000
M86-M90 Other osteopathies
0.627 0.373 0.000
M23 Internal derangement of knee
0.627 0.373 0.000
I46.1 Sudden cardiac death, so described
0.627 0.373 0.000
S82.4 Fracture of fibula alone
0.627 0.373 0.000
H01.0 Blepharitis
0.626 0.374 0.000
I45.8 Other specified conduction disorders
0.625 0.374 0.000
I45.4 Nonspecific intraventricular block
0.625 0.374 0.000
I45.2 Bifascicular block
0.625 0.374 0.000
I45.0 Right fascicular block
0.625 0.374 0.000
F81 Specific developmental disorders of scholastic skills
0.625 0.375 0.000
M21.9 Acquired deformity of limb, unspecified
0.624 0.375 0.000
M21.8 Other specified acquired deformities of limbs
0.624 0.375 0.000
M21.7 Unequal limb length (acquired)
0.624 0.375 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.624 0.375 0.000
M21.2 Flexion deformity
0.624 0.375 0.000
S01.2 Open wound of nose
0.623 0.377 0.000
I27 Other pulmonary heart diseases
0.623 0.377 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.623 0.377 0.000
M25.52 Pain in joint (Upper arm)
0.623 0.377 0.000
S05.1 Contusion of eyeball and orbital tissues
0.622 0.378 0.000
B99 Other and unspecified infectious diseases
0.621 0.379 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.621 0.379 0.000
I34.1 Mitral (valve) prolapse
0.621 0.379 0.000
S92.3 Fracture of metatarsal bone
0.621 0.379 0.000
H18.6 Keratoconus
0.620 0.380 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.620 0.380 0.000
H43 Disorders of vitreous body
0.620 0.380 0.000
T98 Sequelae of other and unspecified effects of external causes
0.619 0.381 0.000
H52.6 Other disorders of refraction
0.619 0.381 0.000
H52.5 Disorders of accommodation
0.619 0.381 0.000
H52.4 Presbyopia
0.619 0.381 0.000
S98 Traumatic amputation of ankle and foot
0.618 0.382 0.000
S97 Crushing injury of ankle and foot
0.618 0.382 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.618 0.382 0.000
S95 Injury of blood vessels at ankle and foot level
0.618 0.382 0.000
S94 Injury of nerves at ankle and foot level
0.618 0.382 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.618 0.382 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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