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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77603112
log Bayes Factor = 33.2101
Chromosome 15   position 47,488,446  (GRCh37) Explore rs77603112 on Ensembl!
Variant rs77603112 is part of Cluster X0085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
K44 Diaphragmatic hernia
0.997 0.003 0.000
K40-K46 Hernia
0.996 0.004 0.000
Z51.3 Blood transfusion without reported diagnosis
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.992 0.008 0.000
Z51.0 Radiotherapy session
0.988 0.012 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.987 0.013 0.000
Z98 Other postsurgical states
0.987 0.013 0.000
I10-I15 Hypertensive diseases
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.985 0.015 0.000
D12.3 Transverse colon
0.983 0.017 0.000
Z87 Personal history of other diseases and conditions
0.983 0.017 0.000
Z80 Family history of malignant neoplasm
0.982 0.018 0.000
I10 Essential (primary) hypertension
0.979 0.021 0.000
Z51.1 Chemotherapy session for neoplasm
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.969 0.031 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.968 0.032 0.000
I35 Nonrheumatic aortic valve disorders
0.968 0.032 0.000
J30-J39 Other diseases of upper respiratory tract
0.968 0.032 0.000
D12.0 Caecum
0.964 0.036 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.964 0.036 0.000
Z83 Family history of other specific disorders
0.963 0.037 0.000
C79 Secondary malignant neoplasm of other sites
0.962 0.038 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.959 0.041 0.000
J90-J94 Other diseases of pleura
0.957 0.043 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.956 0.044 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.955 0.045 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.953 0.047 0.000
Z87.1 Personal history of diseases of the digestive system
0.953 0.047 0.000
Z13 Special screening examination for other diseases and disorders
0.942 0.058 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.940 0.060 0.000
C18 Malignant neoplasm of colon
0.939 0.061 0.000
Chapter VII Diseases of the eye and adnexa
0.937 0.063 0.000
Z86 Personal history of certain other diseases
0.935 0.065 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.935 0.065 0.000
J40-J47 Chronic lower respiratory diseases
0.934 0.066 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.933 0.067 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.933 0.067 0.000
I35.0 Aortic (valve) stenosis
0.933 0.067 0.000
Z60 Problems related to social environment
0.933 0.067 0.000
Z98.8 Other specified postsurgical states
0.923 0.077 0.000
R50-R69 General symptoms and signs
0.921 0.079 0.000
C77.3 Axillary and upper limb lymph nodes
0.920 0.080 0.000
K90-K93 Other diseases of the digestive system
0.919 0.081 0.000
S00-S09 Injuries to the head
0.918 0.082 0.000
M70-M79 Other soft tissue disorders
0.918 0.082 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
R47-R49 Symptoms and signs involving speech and voice
0.913 0.087 0.000
Z98.0 Intestinal bypass and anastomosis status
0.908 0.092 0.000
Z86.4 Personal history of psychoactive substance abuse
0.907 0.093 0.000
T81 Complications of procedures, not elsewhere classified
0.907 0.093 0.000
Z60.2 Living alone
0.907 0.093 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.907 0.093 0.000
Z90.1 Acquired absence of breast(s)
0.905 0.095 0.000
M20-M25 Other joint disorders
0.902 0.098 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.901 0.099 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.900 0.100 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.898 0.102 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.898 0.102 0.000
I05-I09 Chronic rheumatic heart diseases
0.897 0.103 0.000
C77.0 Lymph nodes of head, face and neck
0.896 0.104 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.892 0.108 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.892 0.108 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.890 0.110 0.000
E20-E35 Disorders of other endocrine glands
0.890 0.110 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.889 0.111 0.000
Z92 Personal history of medical treatment
0.889 0.111 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.889 0.111 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.887 0.113 0.000
C50-C50 Malignant neoplasm of breast
0.885 0.115 0.000
K92 Other diseases of digestive system
0.882 0.118 0.000
T66-T78 Other and unspecified effects of external causes
0.881 0.119 0.000
Z93 Artificial opening status
0.880 0.120 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.880 0.120 0.000
E00-E07 Disorders of thyroid gland
0.880 0.120 0.000
Z40 Prophylactic surgery
0.879 0.121 0.000
J90 Pleural effusion, not elsewhere classified
0.879 0.121 0.000
M80-M85 Disorders of bone density and structure
0.877 0.123 0.000
D18 Haemangioma and lymphangioma, any site
0.876 0.124 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.874 0.126 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.871 0.129 0.000
Z83.5 Family history of eye and ear disorders
0.871 0.129 0.000
I51 Complications and ill-defined descriptions of heart disease
0.870 0.130 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.869 0.131 0.000
Chapter XXII Codes for special purposes
0.868 0.132 0.000
C18.0 Caecum
0.867 0.133 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.865 0.135 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.865 0.135 0.000
Chapter I Certain infectious and parasitic diseases
0.864 0.136 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.864 0.136 0.000
K92.0 Haematemesis
0.864 0.136 0.000
Y43 Primarily systemic agents
0.862 0.138 0.000
D12.4 Descending colon
0.860 0.140 0.000
W00-W19 Falls
0.860 0.140 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.859 0.141 0.000
R69 Unknown and unspecified causes of morbidity
0.859 0.141 0.000
C51-C58 Malignant neoplasms of female genital organs
0.859 0.141 0.000
J44 Other chronic obstructive pulmonary disease
0.857 0.143 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.857 0.143 0.000
M40-M43 Deforming dorsopathies
0.856 0.144 0.000
M86-M90 Other osteopathies
0.854 0.146 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.853 0.147 0.000
M50-M54 Other dorsopathies
0.853 0.147 0.000
K29 Gastritis and duodenitis
0.853 0.147 0.000
C16 Malignant neoplasm of stomach
0.852 0.148 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.850 0.150 0.000
D00-D09 In situ neoplasms
0.850 0.150 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.849 0.151 0.000
M15-M19 Arthrosis
0.849 0.151 0.000
Z87.0 Personal history of diseases of the respiratory system
0.848 0.152 0.000
K29.8 Duodenitis
0.844 0.156 0.000
I35.9 Aortic valve disorder, unspecified
0.844 0.156 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.843 0.157 0.000
Z98.1 Arthrodesis status
0.839 0.161 0.000
J93 Pneumothorax
0.838 0.162 0.000
T91 Sequelae of injuries of neck and trunk
0.837 0.163 0.000
Z80.3 Family history of malignant neoplasm of breast
0.836 0.164 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.835 0.165 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.833 0.167 0.000
R49 Voice disturbances
0.830 0.170 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.830 0.170 0.000
S20-S29 Injuries to the thorax
0.830 0.170 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.829 0.171 0.000
I49 Other cardiac arrhythmias
0.826 0.174 0.000
R55 Syncope and collapse
0.826 0.174 0.000
S80-S89 Injuries to the knee and lower leg
0.825 0.175 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.825 0.175 0.000
M79.8 Other specified soft tissue disorders
0.824 0.176 0.000
J33 Nasal polyp
0.824 0.176 0.000
Chapter VI Diseases of the nervous system
0.824 0.176 0.000
C77.2 Intra-abdominal lymph nodes
0.823 0.177 0.000
E65-E68 Obesity and other hyperalimentation
0.823 0.177 0.000
R20 Disturbances of skin sensation
0.823 0.177 0.000
Y43.3 Other antineoplastic drugs
0.822 0.178 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.821 0.179 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.820 0.180 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.819 0.181 0.000
D26 Other benign neoplasms of uterus
0.819 0.181 0.000
S01 Open wound of head
0.819 0.181 0.000
Z83.7 Family history of diseases of the digestive system
0.819 0.181 0.000
M24 Other specific joint derangements
0.819 0.181 0.000
J46 Status asthmaticus
0.819 0.181 0.000
I45 Other conduction disorders
0.817 0.183 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.816 0.184 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.816 0.184 0.000
D22 Melanocytic naevi
0.815 0.185 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.815 0.185 0.000
I08 Multiple valve diseases
0.814 0.186 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.813 0.187 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.813 0.187 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.811 0.189 0.000
T90 Sequelae of injuries of head
0.810 0.190 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.810 0.190 0.000
M18 Arthrosis of first carpometacarpal joint
0.809 0.191 0.000
C80 Malignant neoplasm without specification of site
0.808 0.191 0.000
I50 Heart failure
0.808 0.192 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.807 0.193 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.806 0.194 0.000
I51.8 Other ill-defined heart diseases
0.805 0.195 0.000
J32 Chronic sinusitis
0.805 0.195 0.000
Chapter V Mental and behavioural disorders
0.805 0.195 0.000
J47 Bronchiectasis
0.805 0.195 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.804 0.196 0.000
Z45 Adjustment and management of implanted device
0.804 0.196 0.000
C50 Malignant neoplasm of breast
0.802 0.198 0.000
Z57 Occupational exposure to risk-factors
0.802 0.198 0.000
H53-H54 Visual disturbances and blindness
0.801 0.199 0.000
M25 Other joint disorders, not elsewhere classified
0.800 0.200 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.799 0.201 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.798 0.202 0.000
J94 Other pleural conditions
0.798 0.202 0.000
H55-H59 Other disorders of eye and adnexa
0.797 0.202 0.000
T78 Adverse effects, not elsewhere classified
0.796 0.204 0.000
J00-J06 Acute upper respiratory infections
0.796 0.204 0.000
M91-M94 Chondropathies
0.795 0.205 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.795 0.205 0.000
E23 Hypofunction and other disorders of pituitary gland
0.794 0.206 0.000
M45-M49 Spondylopathies
0.794 0.206 0.000
Z00.0 General medical examination
0.794 0.206 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.793 0.207 0.000
D11 Benign neoplasm of major salivary glands
0.792 0.208 0.000
C77.1 Intrathoracic lymph nodes
0.792 0.208 0.000
M54 Dorsalgia
0.791 0.209 0.000
D18.0 Haemangioma, any site
0.791 0.209 0.000
H02 Other disorders of eyelid
0.790 0.210 0.000
Z02 Examination and encounter for administrative purposes
0.789 0.211 0.000
C21 Malignant neoplasm of anus and anal canal
0.787 0.213 0.000
Z94 Transplanted organ and tissue status
0.786 0.214 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.786 0.214 0.000
R20.2 Paraesthesia of skin
0.786 0.214 0.000
Z01.9 Special examination, unspecified
0.786 0.214 0.000
C79.2 Secondary malignant neoplasm of skin
0.786 0.214 0.000
Z95.2 Presence of prosthetic heart valve
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.784 0.216 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.784 0.216 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.784 0.216 0.000
I35.1 Aortic (valve) insufficiency
0.784 0.216 0.000
I60-I69 Cerebrovascular diseases
0.783 0.217 0.000
J35 Chronic diseases of tonsils and adenoids
0.783 0.217 0.000
I47 Paroxysmal tachycardia
0.782 0.218 0.000
M65-M68 Disorders of synovium and tendon
0.780 0.219 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.780 0.220 0.000
C17 Malignant neoplasm of small intestine
0.780 0.220 0.000
E03 Other hypothyroidism
0.780 0.220 0.000
Z51.5 Palliative care
0.779 0.221 0.000
Z93.3 Colostomy status
0.778 0.222 0.000
K65-K67 Diseases of peritoneum
0.778 0.222 0.000
I11 Hypertensive heart disease
0.777 0.223 0.000
J31.0 Chronic rhinitis
0.777 0.223 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.777 0.223 0.000
M79.0 Rheumatism, unspecified
0.777 0.223 0.000
T98 Sequelae of other and unspecified effects of external causes
0.777 0.223 0.000
C56 Malignant neoplasm of ovary
0.776 0.224 0.000
T93 Sequelae of injuries of lower limb
0.776 0.224 0.000
R47 Speech disturbances, not elsewhere classified
0.775 0.225 0.000
R79 Other abnormal findings of blood chemistry
0.773 0.227 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.773 0.227 0.000
M43 Other deforming dorsopathies
0.771 0.228 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.771 0.229 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.771 0.229 0.000
R54 Senility
0.770 0.230 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
J36 Peritonsillar abscess
0.770 0.230 0.000
C77.8 Lymph nodes of multiple regions
0.767 0.233 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.767 0.233 0.000
M19 Other arthrosis
0.766 0.234 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.765 0.235 0.000
D12.9 Anus and anal canal
0.764 0.236 0.000
X60-X84 Intentional self-harm
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.760 0.240 0.000
Z13.5 Special screening examination for eye and ear disorders
0.760 0.240 0.000
C50.9 Breast, unspecified
0.760 0.240 0.000
M24.1 Other articular cartilage disorders
0.759 0.241 0.000
Q60-Q64 Congenital malformations of the urinary system
0.758 0.241 0.000
K11 Diseases of salivary glands
0.758 0.242 0.000
M00-M03 Infectious arthropathies
0.758 0.242 0.000
T92 Sequelae of injuries of upper limb
0.757 0.243 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.757 0.243 0.000
C18.4 Transverse colon
0.756 0.244 0.000
C73 Malignant neoplasm of thyroid gland
0.755 0.245 0.000
H43-H45 Disorders of vitreous body and globe
0.754 0.246 0.000
C09 Malignant neoplasm of tonsil
0.753 0.247 0.000
Q00-Q07 Congenital malformations of the nervous system
0.753 0.247 0.000
K46 Unspecified abdominal hernia
0.752 0.248 0.000
J93.9 Pneumothorax, unspecified
0.752 0.248 0.000
K07 Dentofacial anomalies [including malocclusion]
0.751 0.249 0.000
I36 Nonrheumatic tricuspid valve disorders
0.749 0.250 0.000
K29.0 Acute haemorrhagic gastritis
0.749 0.251 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.749 0.251 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.749 0.251 0.000
C18.9 Colon, unspecified
0.748 0.252 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.746 0.253 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.746 0.254 0.000
Z51.9 Medical care, unspecified
0.745 0.255 0.000
Z01.6 Radiological examination, not elsewhere classified
0.745 0.255 0.000
J09-J18 Influenza and pneumonia
0.745 0.255 0.000
M20 Acquired deformities of fingers and toes
0.745 0.255 0.000
C01 Malignant neoplasm of base of tongue
0.745 0.255 0.000
Z95.4 Presence of other heart-valve replacement
0.744 0.256 0.000
J91 Pleural effusion in conditions classified elsewhere
0.744 0.256 0.000
R63 Symptoms and signs concerning food and fluid intake
0.744 0.256 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.744 0.256 0.000
V80-V89 Other land transport accidents
0.744 0.256 0.000
Y44 Agents primarily affecting blood constituents
0.743 0.257 0.000
K10 Other diseases of jaws
0.743 0.257 0.000
C92 Myeloid leukaemia
0.743 0.257 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.741 0.259 0.000
D17 Benign lipomatous neoplasm
0.740 0.260 0.000
K02 Dental caries
0.740 0.260 0.000
E06 Thyroiditis
0.740 0.260 0.000
K14 Diseases of tongue
0.740 0.260 0.000
D05 Carcinoma in situ of breast
0.740 0.260 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.739 0.260 0.000
Z83.3 Family history of diabetes mellitus
0.739 0.261 0.000
C77.5 Intrapelvic lymph nodes
0.739 0.261 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.739 0.261 0.000
E40-E46 Malnutrition
0.738 0.262 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.737 0.263 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.736 0.264 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.736 0.264 0.000
S00 Superficial injury of head
0.735 0.265 0.000
K00 Disorders of tooth development and eruption
0.734 0.266 0.000
M85 Other disorders of bone density and structure
0.733 0.267 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.732 0.268 0.000
R49.0 Dysphonia
0.731 0.269 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.731 0.269 0.000
J95-J99 Other diseases of the respiratory system
0.730 0.270 0.000
J40 Bronchitis, not specified as acute or chronic
0.730 0.270 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.729 0.271 0.000
Z41 Procedures for purposes other than remedying health state
0.729 0.271 0.000
I38 Endocarditis, valve unspecified
0.729 0.271 0.000
M79.1 Myalgia
0.729 0.271 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.728 0.272 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.728 0.272 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.728 0.272 0.000
B95-B98 Bacterial, viral and other infectious agents
0.728 0.272 0.000
E66 Obesity
0.728 0.272 0.000
Z89 Acquired absence of limb
0.727 0.273 0.000
W19 Unspecified fall
0.727 0.273 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.727 0.273 0.000
C50.4 Upper-outer quadrant of breast
0.727 0.273 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.726 0.274 0.000
S09 Other and unspecified injuries of head
0.726 0.274 0.000
C18.7 Sigmoid colon
0.726 0.274 0.000
I08.0 Disorders of both mitral and aortic valves
0.725 0.275 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
M79.7 Fibromyalgia
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.276 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.723 0.277 0.000
R52 Pain, not elsewhere classified
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.279 0.000
C18.3 Hepatic flexure
0.721 0.279 0.000
I49.9 Cardiac arrhythmia, unspecified
0.720 0.280 0.000
E28 Ovarian dysfunction
0.719 0.281 0.000
C90.0 Multiple myeloma
0.718 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z51.6 Desensitisation to allergens
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Z13.1 Special screening examination for diabetes mellitus
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
I45.6 Preexcitation syndrome
0.716 0.284 0.000
Z49 Care involving dialysis
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
K44.1 Diaphragmatic hernia with gangrene
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.715 0.285 0.000
Z93.1 Gastrostomy status
0.715 0.285 0.000
K45 Other abdominal hernia
0.714 0.286 0.000
Z97 Presence of other devices
0.714 0.286 0.000
Q23 Congenital malformations of aortic and mitral valves
0.713 0.287 0.000
D31 Benign neoplasm of eye and adnexa
0.713 0.287 0.000
D30 Benign neoplasm of urinary organs
0.713 0.287 0.000
D29 Benign neoplasm of male genital organs
0.713 0.287 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.713 0.287 0.000
D19 Benign neoplasm of mesothelial tissue
0.713 0.287 0.000
D16 Benign neoplasm of bone and articular cartilage
0.713 0.287 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.713 0.287 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.713 0.287 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.713 0.287 0.000
Y40 Systemic antibiotics
0.712 0.288 0.000
C52 Malignant neoplasm of vagina
0.712 0.288 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.711 0.289 0.000
D12.1 Appendix
0.711 0.289 0.000
M43.1 Spondylolisthesis
0.711 0.289 0.000
C16.9 Stomach, unspecified
0.711 0.289 0.000
S81 Open wound of lower leg
0.710 0.290 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.710 0.290 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.710 0.290 0.000
B99-B99 Other infectious diseases
0.709 0.290 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.709 0.291 0.000
I05 Rheumatic mitral valve diseases
0.708 0.292 0.000
H02.0 Entropion and trichiasis of eyelid
0.708 0.292 0.000
E03.9 Hypothyroidism, unspecified
0.708 0.292 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.707 0.293 0.000
I15 Secondary hypertension
0.707 0.293 0.000
I13 Hypertensive heart and renal disease
0.707 0.293 0.000
Z13.9 Special screening examination, unspecified
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.293 0.000
I48 Atrial fibrillation and flutter
0.706 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.293 0.000
I40 Acute myocarditis
0.706 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.293 0.000
I37 Pulmonary valve disorders
0.706 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.293 0.000
C16.3 Pyloric antrum
0.706 0.294 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.706 0.294 0.000
K09 Cysts of oral region, not elsewhere classified
0.706 0.294 0.000
J33.0 Polyp of nasal cavity
0.705 0.295 0.000
C26.0 Intestinal tract, part unspecified
0.705 0.295 0.000
K29.3 Chronic superficial gastritis
0.705 0.295 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.704 0.295 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.704 0.296 0.000
Z80.6 Family history of leukaemia
0.704 0.296 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.704 0.296 0.000
R45 Symptoms and signs involving emotional state
0.704 0.296 0.000
Z86.7 Personal history of diseases of the circulatory system
0.703 0.297 0.000
R47.8 Other and unspecified speech disturbances
0.702 0.298 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.702 0.298 0.000
J31.2 Chronic pharyngitis
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.701 0.299 0.000
R23 Other skin changes
0.701 0.299 0.000
D04 Carcinoma in situ of skin
0.700 0.300 0.000
J33.8 Other polyp of sinus
0.700 0.300 0.000
R51 Headache
0.700 0.300 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.699 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.699 0.301 0.000
Z54 Convalescence
0.699 0.301 0.000
E04 Other non-toxic goitre
0.699 0.301 0.000
Z82.3 Family history of stroke
0.698 0.302 0.000
K22 Other diseases of oesophagus
0.697 0.303 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.304 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
R57 Shock, not elsewhere classified
0.696 0.304 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.695 0.305 0.000
M81 Osteoporosis without pathological fracture
0.695 0.305 0.000
Z65 Problems related to other psychosocial circumstances
0.695 0.305 0.000
Z64 Problems related to certain psychosocial circumstances
0.695 0.305 0.000
Z62 Other problems related to upbringing
0.695 0.305 0.000
Z61 Problems related to negative life events in childhood
0.695 0.305 0.000
Z59 Problems related to housing and economic circumstances
0.695 0.305 0.000
Z58 Problems related to physical environment
0.695 0.305 0.000
Z56 Problems related to employment and unemployment
0.695 0.305 0.000
Z55 Problems related to education and literacy
0.695 0.305 0.000
J32.9 Chronic sinusitis, unspecified
0.694 0.306 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.694 0.306 0.000
Z90.0 Acquired absence of part of head and neck
0.694 0.306 0.000
M54.4 Lumbago with sciatica
0.694 0.306 0.000
J37 Chronic laryngitis and laryngotracheitis
0.694 0.306 0.000
C18.2 Ascending colon
0.694 0.306 0.000
I42 Cardiomyopathy
0.693 0.306 0.000
I35.8 Other aortic valve disorders
0.693 0.307 0.000
C77.9 Lymph node, unspecified
0.693 0.307 0.000
Q21 Congenital malformations of cardiac septa
0.693 0.307 0.000
R42 Dizziness and giddiness
0.693 0.307 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.692 0.308 0.000
B35-B49 Mycoses
0.692 0.308 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.691 0.309 0.000
T95 Sequelae of burns, corrosions and frostbite
0.691 0.309 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.691 0.309 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.691 0.309 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.691 0.309 0.000
Z63 Other problems related to primary support group, including family circumstances
0.691 0.309 0.000
Z83.6 Family history of diseases of the respiratory system
0.690 0.310 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.690 0.310 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.690 0.310 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.690 0.310 0.000
W08 Fall involving other furniture
0.690 0.310 0.000
C79.6 Secondary malignant neoplasm of ovary
0.690 0.310 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.690 0.310 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.690 0.310 0.000
R49.8 Other and unspecified voice disturbances
0.690 0.310 0.000
H02.8 Other specified disorders of eyelid
0.690 0.310 0.000
D10 Benign neoplasm of mouth and pharynx
0.689 0.311 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.689 0.311 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.689 0.311 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.689 0.311 0.000
S32 Fracture of lumbar spine and pelvis
0.688 0.311 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.688 0.312 0.000
R50 Fever of unknown origin
0.688 0.312 0.000
M79.6 Pain in limb
0.688 0.312 0.000
T91.3 Sequelae of injury of spinal cord
0.687 0.313 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.687 0.313 0.000
H05 Disorders of orbit
0.687 0.313 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.687 0.313 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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