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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77780208
log Bayes Factor = 5.21025
Chromosome 5   position 104,879,134  (GRCh37) Explore rs77780208 on Ensembl!
Variant rs77780208 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.968 0.032 0.000
Chapter IX Diseases of the circulatory system
0.963 0.037 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.960 0.040 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.943 0.057 0.000
I20-I25 Ischaemic heart diseases
0.939 0.061 0.000
K22 Other diseases of oesophagus
0.917 0.083 0.000
Chapter V Mental and behavioural disorders
0.907 0.093 0.000
K55-K64 Other diseases of intestines
0.895 0.105 0.000
Chapter XIV Diseases of the genitourinary system
0.884 0.116 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.883 0.117 0.000
I25 Chronic ischaemic heart disease
0.878 0.122 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.877 0.123 0.000
K29 Gastritis and duodenitis
0.875 0.125 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.874 0.126 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.860 0.140 0.000
R50-R69 General symptoms and signs
0.854 0.146 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.849 0.151 0.000
I20 Angina pectoris
0.830 0.170 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.828 0.171 0.000
G56 Mononeuropathies of upper limb
0.828 0.172 0.000
K22.1 Ulcer of oesophagus
0.827 0.173 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.826 0.174 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.826 0.174 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.826 0.174 0.000
Chapter I Certain infectious and parasitic diseases
0.819 0.181 0.000
K21 Gastro-oesophageal reflux disease
0.818 0.182 0.000
Z87 Personal history of other diseases and conditions
0.817 0.183 0.000
R07 Pain in throat and chest
0.816 0.184 0.000
M05-M14 Inflammatory polyarthropathies
0.816 0.184 0.000
M15-M19 Arthrosis
0.816 0.184 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.805 0.195 0.000
I25.2 Old myocardial infarction
0.797 0.203 0.000
K31 Other diseases of stomach and duodenum
0.797 0.203 0.000
K30 Dyspepsia
0.796 0.204 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.790 0.210 0.000
K29.7 Gastritis, unspecified
0.788 0.212 0.000
K25 Gastric ulcer
0.785 0.215 0.000
K63 Other diseases of intestine
0.781 0.219 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.779 0.221 0.000
M45-M49 Spondylopathies
0.779 0.221 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.778 0.222 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.772 0.228 0.000
I60-I69 Cerebrovascular diseases
0.771 0.229 0.000
K40-K46 Hernia
0.769 0.231 0.000
K90-K93 Other diseases of the digestive system
0.765 0.235 0.000
Z96 Presence of other functional implants
0.765 0.235 0.000
K26 Duodenal ulcer
0.763 0.237 0.000
Z98 Other postsurgical states
0.761 0.238 0.000
G56.0 Carpal tunnel syndrome
0.761 0.239 0.000
G40-G47 Episodic and paroxysmal disorders
0.760 0.240 0.000
K35-K38 Diseases of appendix
0.760 0.240 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.759 0.241 0.000
K58 Irritable bowel syndrome
0.757 0.243 0.000
M50-M54 Other dorsopathies
0.751 0.249 0.000
I21 Acute myocardial infarction
0.747 0.253 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.743 0.257 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.740 0.260 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.738 0.262 0.000
K50-K52 Noninfective enteritis and colitis
0.735 0.264 0.000
Chapter II Neoplasms
0.735 0.265 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.734 0.265 0.000
F17.1 Harmful use
0.732 0.268 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.732 0.268 0.000
Chapter XX External causes of morbidity and mortality
0.732 0.268 0.000
E00-E07 Disorders of thyroid gland
0.731 0.269 0.000
K20 Oesophagitis
0.731 0.269 0.000
M20-M25 Other joint disorders
0.722 0.278 0.000
K22.7 Barrett's oesophagus
0.721 0.279 0.000
Z88.0 Personal history of allergy to penicillin
0.718 0.282 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.717 0.283 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
R07.4 Chest pain, unspecified
0.716 0.284 0.000
K70-K77 Diseases of liver
0.716 0.284 0.000
K65-K67 Diseases of peritoneum
0.715 0.285 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.715 0.285 0.000
Z95.1 Presence of aortocoronary bypass graft
0.714 0.286 0.000
N60-N64 Disorders of breast
0.714 0.286 0.000
M19 Other arthrosis
0.714 0.286 0.000
K22.2 Oesophageal obstruction
0.712 0.288 0.000
K28 Gastrojejunal ulcer
0.711 0.289 0.000
K27 Peptic ulcer, site unspecified
0.711 0.289 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.708 0.291 0.000
Chapter X Diseases of the respiratory system
0.707 0.293 0.000
I20.0 Unstable angina
0.707 0.293 0.000
K57 Diverticular disease of intestine
0.707 0.293 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.704 0.296 0.000
R07.3 Other chest pain
0.704 0.296 0.000
K63.5 Polyp of colon
0.700 0.300 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.700 0.300 0.000
N30-N39 Other diseases of urinary system
0.698 0.302 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.697 0.303 0.000
M13 Other arthritis
0.697 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.694 0.306 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.694 0.306 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.694 0.306 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.694 0.306 0.000
R47-R49 Symptoms and signs involving speech and voice
0.694 0.306 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.694 0.306 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.691 0.309 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.691 0.309 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.691 0.309 0.000
I05-I09 Chronic rheumatic heart diseases
0.691 0.309 0.000
I00-I02 Acute rheumatic fever
0.691 0.309 0.000
G56.2 Lesion of ulnar nerve
0.690 0.310 0.000
Z86 Personal history of certain other diseases
0.690 0.310 0.000
Z88.6 Personal history of allergy to analgesic agent
0.690 0.310 0.000
R42 Dizziness and giddiness
0.688 0.312 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.688 0.312 0.000
Z97 Presence of other devices
0.688 0.312 0.000
Z94 Transplanted organ and tissue status
0.688 0.312 0.000
Z93 Artificial opening status
0.688 0.312 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.688 0.312 0.000
Z89 Acquired absence of limb
0.688 0.312 0.000
Z84 Family history of other conditions
0.688 0.312 0.000
Z83 Family history of other specific disorders
0.688 0.312 0.000
Z81 Family history of mental and behavioural disorders
0.688 0.312 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.687 0.312 0.000
H25-H28 Disorders of lens
0.686 0.314 0.000
K29.8 Duodenitis
0.685 0.315 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.685 0.315 0.000
M91-M94 Chondropathies
0.685 0.315 0.000
M86-M90 Other osteopathies
0.685 0.315 0.000
M80-M85 Disorders of bone density and structure
0.685 0.315 0.000
M65-M68 Disorders of synovium and tendon
0.685 0.315 0.000
M60-M63 Disorders of muscles
0.685 0.315 0.000
M40-M43 Deforming dorsopathies
0.685 0.315 0.000
M00-M03 Infectious arthropathies
0.685 0.315 0.000
I20.9 Angina pectoris, unspecified
0.682 0.318 0.000
R51 Headache
0.681 0.319 0.000
I30-I52 Other forms of heart disease
0.679 0.321 0.000
R63 Symptoms and signs concerning food and fluid intake
0.678 0.322 0.000
G90-G99 Other disorders of the nervous system
0.676 0.324 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.676 0.324 0.000
G70-G73 Diseases of myoneural junction and muscle
0.676 0.324 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.676 0.324 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.676 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.676 0.324 0.000
G20-G26 Extrapyramidal and movement disorders
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.676 0.324 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.673 0.327 0.000
I23 Certain current complications following acute myocardial infarction
0.673 0.327 0.000
I22 Subsequent myocardial infarction
0.673 0.327 0.000
F30-F39 Mood [affective] disorders
0.671 0.329 0.000
M70-M79 Other soft tissue disorders
0.671 0.329 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.670 0.330 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.663 0.337 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.659 0.341 0.000
Z87.1 Personal history of diseases of the digestive system
0.658 0.342 0.000
K22.9 Disease of oesophagus, unspecified
0.657 0.343 0.000
K22.8 Other specified diseases of oesophagus
0.657 0.343 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.657 0.343 0.000
K22.5 Diverticulum of oesophagus, acquired
0.657 0.343 0.000
K22.4 Dyskinesia of oesophagus
0.657 0.343 0.000
K22.3 Perforation of oesophagus
0.657 0.343 0.000
K22.0 Achalasia of cardia
0.657 0.343 0.000
K31.7 Polyp of stomach and duodenum
0.657 0.343 0.000
Z13 Special screening examination for other diseases and disorders
0.657 0.343 0.000
R59 Enlarged lymph nodes
0.656 0.344 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.655 0.345 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.655 0.345 0.000
H30-H36 Disorders of choroid and retina
0.654 0.346 0.000
Z90.7 Acquired absence of genital organ(s)
0.653 0.347 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.653 0.347 0.000
M47 Spondylosis
0.653 0.347 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.652 0.348 0.000
F99-F99 Unspecified mental disorder
0.650 0.350 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.650 0.350 0.000
F80-F89 Disorders of psychological development
0.650 0.350 0.000
F70-F79 Mental retardation
0.650 0.350 0.000
F60-F69 Disorders of adult personality and behaviour
0.650 0.350 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.650 0.350 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.650 0.350 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.650 0.350 0.000
R00 Abnormalities of heart beat
0.648 0.352 0.000
E03 Other hypothyroidism
0.647 0.353 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.647 0.353 0.000
B35-B49 Mycoses
0.646 0.354 0.000
B95-B98 Bacterial, viral and other infectious agents
0.644 0.356 0.000
R55 Syncope and collapse
0.642 0.358 0.000
I10-I15 Hypertensive diseases
0.642 0.358 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.642 0.358 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.642 0.358 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.641 0.358 0.000
K61 Abscess of anal and rectal regions
0.641 0.358 0.000
K60 Fissure and fistula of anal and rectal regions
0.641 0.358 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.641 0.358 0.000
K55 Vascular disorders of intestine
0.641 0.358 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.641 0.359 0.000
K44 Diaphragmatic hernia
0.641 0.359 0.000
M19.9 Arthrosis, unspecified
0.640 0.360 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.640 0.360 0.000
M17 Gonarthrosis [arthrosis of knee]
0.639 0.360 0.000
R53 Malaise and fatigue
0.639 0.361 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.638 0.362 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.638 0.362 0.000
E65-E68 Obesity and other hyperalimentation
0.635 0.364 0.000
E70-E90 Metabolic disorders
0.634 0.366 0.000
N99-N99 Other disorders of the genitourinary system
0.634 0.366 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.634 0.366 0.000
N25-N29 Other disorders of kidney and ureter
0.634 0.366 0.000
N20-N23 Urolithiasis
0.634 0.366 0.000
N10-N16 Renal tubulo-interstitial diseases
0.634 0.366 0.000
N00-N08 Glomerular diseases
0.634 0.366 0.000
I63 Cerebral infarction
0.633 0.367 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.633 0.367 0.000
G58 Other mononeuropathies
0.633 0.367 0.000
G57 Mononeuropathies of lower limb
0.633 0.367 0.000
G54 Nerve root and plexus disorders
0.633 0.367 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.633 0.367 0.000
G52 Disorders of other cranial nerves
0.633 0.367 0.000
G51 Facial nerve disorders
0.633 0.367 0.000
G50 Disorders of trigeminal nerve
0.633 0.367 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.633 0.367 0.000
K13 Other diseases of lip and oral mucosa
0.631 0.369 0.000
Z72 Problems related to lifestyle
0.630 0.370 0.000
I25.6 Silent myocardial ischaemia
0.630 0.370 0.000
I25.5 Ischaemic cardiomyopathy
0.630 0.370 0.000
I25.4 Coronary artery aneurysm
0.630 0.370 0.000
I25.3 Aneurysm of heart
0.630 0.370 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.630 0.370 0.000
N84 Polyp of female genital tract
0.629 0.371 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.628 0.371 0.000
Z10 Routine general health check-up of defined subpopulation
0.628 0.371 0.000
Z04 Examination and observation for other reasons
0.628 0.371 0.000
Z02 Examination and encounter for administrative purposes
0.628 0.371 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.628 0.371 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.628 0.371 0.000
I25.1 Atherosclerotic heart disease
0.627 0.372 0.000
K29.9 Gastroduodenitis, unspecified
0.627 0.373 0.000
K29.5 Chronic gastritis, unspecified
0.627 0.373 0.000
K29.4 Chronic atrophic gastritis
0.627 0.373 0.000
K29.3 Chronic superficial gastritis
0.627 0.373 0.000
K29.2 Alcoholic gastritis
0.627 0.373 0.000
K29.1 Other acute gastritis
0.627 0.373 0.000
K29.0 Acute haemorrhagic gastritis
0.627 0.373 0.000
N40-N51 Diseases of male genital organs
0.626 0.373 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.626 0.373 0.000
R04 Haemorrhage from respiratory passages
0.626 0.373 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.626 0.373 0.000
R01 Cardiac murmurs and other cardiac sounds
0.626 0.373 0.000
R05 Cough
0.626 0.373 0.000
R02 Gangrene, not elsewhere classified
0.626 0.373 0.000
K02 Dental caries
0.624 0.375 0.000
M10 Gout
0.624 0.376 0.000
R07.2 Precordial pain
0.621 0.379 0.000
Z96.1 Presence of intraocular lens
0.621 0.379 0.000
Z98.0 Intestinal bypass and anastomosis status
0.619 0.381 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.616 0.384 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.616 0.384 0.000
Z88.5 Personal history of allergy to narcotic agent
0.616 0.384 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.616 0.384 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.616 0.384 0.000
Z88.2 Personal history of allergy to sulphonamides
0.616 0.384 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.614 0.386 0.000
R68 Other general symptoms and signs
0.612 0.387 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.612 0.387 0.000
R62 Lack of expected normal physiological development
0.612 0.387 0.000
R61 Hyperhidrosis
0.612 0.387 0.000
R60 Oedema, not elsewhere classified
0.612 0.387 0.000
R57 Shock, not elsewhere classified
0.612 0.387 0.000
R56 Convulsions, not elsewhere classified
0.612 0.387 0.000
R52 Pain, not elsewhere classified
0.612 0.387 0.000
R50 Fever of unknown origin
0.612 0.387 0.000
R64 Cachexia
0.612 0.387 0.000
R58 Haemorrhage, not elsewhere classified
0.612 0.387 0.000
R54 Senility
0.612 0.387 0.000
M13.9 Arthritis, unspecified
0.611 0.389 0.000
Z92 Personal history of medical treatment
0.610 0.389 0.000
R69 Unknown and unspecified causes of morbidity
0.610 0.390 0.000
H55-H59 Other disorders of eye and adnexa
0.609 0.391 0.000
H53-H54 Visual disturbances and blindness
0.609 0.391 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.609 0.391 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.609 0.391 0.000
H43-H45 Disorders of vitreous body and globe
0.609 0.391 0.000
H40-H42 Glaucoma
0.609 0.391 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.609 0.391 0.000
H10-H13 Disorders of conjunctiva
0.609 0.391 0.000
E50-E64 Other nutritional deficiencies
0.608 0.391 0.000
E40-E46 Malnutrition
0.608 0.391 0.000
E20-E35 Disorders of other endocrine glands
0.608 0.391 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.608 0.391 0.000
N17-N19 Renal failure
0.608 0.392 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.607 0.393 0.000
M54 Dorsalgia
0.605 0.395 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.604 0.396 0.000
R14 Flatulence and related conditions
0.602 0.398 0.000
K59 Other functional intestinal disorders
0.602 0.398 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.599 0.401 0.000
K92 Other diseases of digestive system
0.598 0.402 0.000
I20.8 Other forms of angina pectoris
0.595 0.405 0.000
I20.1 Angina pectoris with documented spasm
0.595 0.405 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.594 0.406 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.594 0.406 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.594 0.406 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.594 0.406 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.594 0.406 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.594 0.406 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.594 0.406 0.000
F11 Mental and behavioural disorders due to use of opioids
0.594 0.406 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.594 0.406 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.594 0.406 0.000
G56.8 Other mononeuropathies of upper limb
0.594 0.406 0.000
G56.4 Causalgia
0.594 0.406 0.000
G56.3 Lesion of radial nerve
0.594 0.406 0.000
G56.1 Other lesions of median nerve
0.594 0.406 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.594 0.406 0.000
Z90.8 Acquired absence of other organs
0.592 0.407 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.592 0.407 0.000
Z90.5 Acquired absence of kidney
0.592 0.407 0.000
Z90.3 Acquired absence of part of stomach
0.592 0.407 0.000
Z90.2 Acquired absence of lung [part of]
0.592 0.407 0.000
Z90.1 Acquired absence of breast(s)
0.592 0.407 0.000
Z90.0 Acquired absence of part of head and neck
0.592 0.407 0.000
N62 Hypertrophy of breast
0.592 0.407 0.000
R46 Symptoms and signs involving appearance and behaviour
0.592 0.408 0.000
R45 Symptoms and signs involving emotional state
0.592 0.408 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.592 0.408 0.000
R43 Disturbances of smell and taste
0.592 0.408 0.000
R40 Somnolence, stupor and coma
0.592 0.408 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.592 0.408 0.000
Z95.4 Presence of other heart-valve replacement
0.592 0.408 0.000
Z95.3 Presence of xenogenic heart valve
0.592 0.408 0.000
Z95.2 Presence of prosthetic heart valve
0.592 0.408 0.000
Z95.0 Presence of cardiac pacemaker
0.592 0.408 0.000
Z80 Family history of malignant neoplasm
0.590 0.410 0.000
K35 Acute appendicitis
0.589 0.411 0.000
Z85 Personal history of malignant neoplasm
0.588 0.412 0.000
Z51 Other medical care
0.587 0.413 0.000
B99-B99 Other infectious diseases
0.587 0.413 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.587 0.413 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.587 0.413 0.000
B65-B83 Helminthiases
0.587 0.413 0.000
B50-B64 Protozoal diseases
0.587 0.413 0.000
B25-B34 Other viral diseases
0.587 0.413 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.587 0.413 0.000
B15-B19 Viral hepatitis
0.587 0.413 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.587 0.413 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.587 0.413 0.000
A80-A89 Viral infections of the central nervous system
0.587 0.413 0.000
A75-A79 Rickettsioses
0.587 0.413 0.000
A70-A74 Other diseases caused by chlamydiae
0.587 0.413 0.000
A65-A69 Other spirochaetal diseases
0.587 0.413 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.587 0.413 0.000
A30-A49 Other bacterial diseases
0.587 0.413 0.000
A20-A28 Certain zoonotic bacterial diseases
0.587 0.413 0.000
A15-A19 Tuberculosis
0.587 0.413 0.000
A00-A09 Intestinal infectious diseases
0.587 0.413 0.000
E03.9 Hypothyroidism, unspecified
0.587 0.413 0.000
Z87.8 Personal history of other specified conditions
0.586 0.414 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.586 0.414 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.586 0.414 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.586 0.414 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.586 0.414 0.000
Z87.0 Personal history of diseases of the respiratory system
0.586 0.414 0.000
N95 Menopausal and other perimenopausal disorders
0.586 0.414 0.000
R07.1 Chest pain on breathing
0.585 0.415 0.000
R07.0 Pain in throat
0.585 0.415 0.000
M14 Arthropathies in other diseases classified elsewhere
0.585 0.415 0.000
M12 Other specific arthropathies
0.585 0.415 0.000
M11 Other crystal arthropathies
0.585 0.415 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.585 0.415 0.000
M08 Juvenile arthritis
0.585 0.415 0.000
M07 Psoriatic and enteropathic arthropathies
0.585 0.415 0.000
M06 Other rheumatoid arthritis
0.585 0.415 0.000
M05 Seropositive rheumatoid arthritis
0.585 0.415 0.000
M25 Other joint disorders, not elsewhere classified
0.585 0.415 0.000
M18 Arthrosis of first carpometacarpal joint
0.585 0.415 0.000
M15 Polyarthrosis
0.585 0.415 0.000
I21.9 Acute myocardial infarction, unspecified
0.582 0.418 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.580 0.420 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.579 0.421 0.000
R15 Faecal incontinence
0.578 0.422 0.000
K14 Diseases of tongue
0.577 0.422 0.000
K12 Stomatitis and related lesions
0.577 0.422 0.000
K11 Diseases of salivary glands
0.577 0.422 0.000
K10 Other diseases of jaws
0.577 0.422 0.000
K09 Cysts of oral region, not elsewhere classified
0.577 0.422 0.000
K08 Other disorders of teeth and supporting structures
0.577 0.422 0.000
K07 Dentofacial anomalies [including malocclusion]
0.577 0.422 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.577 0.422 0.000
K05 Gingivitis and periodontal diseases
0.577 0.422 0.000
K04 Diseases of pulp and periapical tissues
0.577 0.422 0.000
K03 Other diseases of hard tissues of teeth
0.577 0.422 0.000
K01 Embedded and impacted teeth
0.577 0.422 0.000
K00 Disorders of tooth development and eruption
0.577 0.422 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.577 0.423 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.576 0.424 0.000
R11 Nausea and vomiting
0.576 0.424 0.000
Z47 Other orthopaedic follow-up care
0.573 0.427 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.571 0.429 0.000
K31.8 Other specified diseases of stomach and duodenum
0.571 0.429 0.000
K31.6 Fistula of stomach and duodenum
0.571 0.429 0.000
K31.5 Obstruction of duodenum
0.571 0.429 0.000
K31.4 Gastric diverticulum
0.571 0.429 0.000
K31.3 Pylorospasm, not elsewhere classified
0.571 0.429 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.571 0.429 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.571 0.429 0.000
K31.0 Acute dilatation of stomach
0.571 0.429 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.570 0.430 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.570 0.430 0.000
E10-E14 Diabetes mellitus
0.569 0.431 0.000
R20 Disturbances of skin sensation
0.567 0.433 0.000
Z54 Convalescence
0.566 0.433 0.000
Z52 Donors of organs and tissues
0.566 0.433 0.000
Z50 Care involving use of rehabilitation procedures
0.566 0.433 0.000
Z49 Care involving dialysis
0.566 0.433 0.000
Z48 Other surgical follow-up care
0.566 0.433 0.000
Z45 Adjustment and management of implanted device
0.566 0.433 0.000
Z44 Fitting and adjustment of external prosthetic device
0.566 0.433 0.000
Z43 Attention to artificial openings
0.566 0.433 0.000
Z42 Follow-up care involving plastic surgery
0.566 0.433 0.000
Z41 Procedures for purposes other than remedying health state
0.566 0.433 0.000
Z40 Prophylactic surgery
0.566 0.433 0.000
K29.6 Other gastritis
0.566 0.434 0.000
K25.7 Chronic without haemorrhage or perforation
0.563 0.437 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.563 0.437 0.000
K25.5 Chronic or unspecified with perforation
0.563 0.437 0.000
K25.4 Chronic or unspecified with haemorrhage
0.563 0.437 0.000
K25.3 Acute without haemorrhage or perforation
0.563 0.437 0.000
K25.2 Acute with both haemorrhage and perforation
0.563 0.437 0.000
K25.1 Acute with perforation
0.563 0.437 0.000
K25.0 Acute with haemorrhage
0.563 0.437 0.000
G40 Epilepsy
0.562 0.437 0.000
M47.8 Other spondylosis
0.562 0.438 0.000
K51 Ulcerative colitis
0.562 0.438 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.561 0.439 0.000
K63.9 Disease of intestine, unspecified
0.560 0.440 0.000
K63.8 Other specified diseases of intestine
0.560 0.440 0.000
K63.4 Enteroptosis
0.560 0.440 0.000
K63.3 Ulcer of intestine
0.560 0.440 0.000
K63.2 Fistula of intestine
0.560 0.440 0.000
K63.1 Perforation of intestine (nontraumatic)
0.560 0.440 0.000
K63.0 Abscess of intestine
0.560 0.440 0.000
K42 Umbilical hernia
0.560 0.440 0.000
Z76 Persons encountering health services in other circumstances
0.559 0.441 0.000
Z75 Problems related to medical facilities and other health care
0.559 0.441 0.000
Z74 Problems related to care-provider dependency
0.559 0.441 0.000
Z73 Problems related to life-management difficulty
0.559 0.441 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.559 0.441 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.559 0.441 0.000
M49 Spondylopathies in diseases classified elsewhere
0.558 0.441 0.000
M48 Other spondylopathies
0.558 0.441 0.000
M46 Other inflammatory spondylopathies
0.558 0.441 0.000
M45 Ankylosing spondylitis
0.558 0.441 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.558 0.442 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.558 0.442 0.000
Z09.4 Follow-up examination after treatment of fracture
0.558 0.442 0.000
Z09.3 Follow-up examination after psychotherapy
0.558 0.442 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.558 0.442 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.558 0.442 0.000
J40-J47 Chronic lower respiratory diseases
0.558 0.442 0.000
R06 Abnormalities of breathing
0.557 0.443 0.000
Z12 Special screening examination for neoplasms
0.556 0.444 0.000
Z96.6 Presence of orthopaedic joint implants
0.554 0.446 0.000
F17.9 Unspecified mental and behavioural disorder
0.554 0.446 0.000
F17.8 Other mental and behavioural disorders
0.554 0.446 0.000
F17.7 Residual and late-onset psychotic disorder
0.554 0.446 0.000
F17.6 Amnesic syndrome
0.554 0.446 0.000
F17.5 Psychotic disorder
0.554 0.446 0.000
F17.4 Withdrawal state with delirium
0.554 0.446 0.000
F17.3 Withdrawal state
0.554 0.446 0.000
F17.2 Dependence syndrome
0.554 0.446 0.000
F17.0 Acute intoxication
0.554 0.446 0.000
M17.9 Gonarthrosis, unspecified
0.554 0.446 0.000
I69 Sequelae of cerebrovascular disease
0.553 0.447 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.553 0.447 0.000
I67 Other cerebrovascular diseases
0.553 0.447 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.553 0.447 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.553 0.447 0.000
I62 Other nontraumatic intracranial haemorrhage
0.553 0.447 0.000
I61 Intracerebral haemorrhage
0.553 0.447 0.000
I60 Subarachnoid haemorrhage
0.553 0.447 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.553 0.447 0.000
R63.4 Abnormal weight loss
0.552 0.448 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.551 0.448 0.000
K46 Unspecified abdominal hernia
0.551 0.448 0.000
K45 Other abdominal hernia
0.551 0.448 0.000
K41 Femoral hernia
0.551 0.448 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.551 0.449 0.000
N84.0 Polyp of corpus uteri
0.551 0.449 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.549 0.450 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.549 0.451 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.549 0.451 0.000
K90 Intestinal malabsorption
0.549 0.451 0.000
Z60 Problems related to social environment
0.549 0.451 0.000
Z72.0 Tobacco use
0.549 0.451 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.549 0.451 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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