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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77795656
log Bayes Factor = 18.6094
Chromosome 2   position 227,058,243  (GRCh37) Explore rs77795656 on Ensembl!
Variant rs77795656 is part of Cluster X0176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.998 0.002 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
M20-M25 Other joint disorders
0.990 0.010 0.000
N17-N19 Renal failure
0.990 0.010 0.000
Chapter II Neoplasms
0.988 0.012 0.000
J09-J18 Influenza and pneumonia
0.986 0.014 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.984 0.016 0.000
N30-N39 Other diseases of urinary system
0.982 0.018 0.000
J18 Pneumonia, organism unspecified
0.982 0.018 0.000
N18 Chronic renal failure
0.981 0.019 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.980 0.020 0.000
Chapter XXI Factors influencing health status and contact with health services
0.980 0.020 0.000
M80-M85 Disorders of bone density and structure
0.979 0.021 0.000
J18.1 Lobar pneumonia, unspecified
0.977 0.023 0.000
M20 Acquired deformities of fingers and toes
0.977 0.023 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.976 0.024 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.972 0.028 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.964 0.036 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.958 0.042 0.000
N92 Excessive, frequent and irregular menstruation
0.956 0.044 0.000
N32 Other disorders of bladder
0.947 0.053 0.000
N84 Polyp of female genital tract
0.947 0.053 0.000
C50-C50 Malignant neoplasm of breast
0.947 0.053 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.944 0.056 0.000
Chapter VII Diseases of the eye and adnexa
0.943 0.057 0.000
Chapter IX Diseases of the circulatory system
0.942 0.058 0.000
O60-O75 Complications of labour and delivery
0.941 0.059 0.000
R50-R69 General symptoms and signs
0.934 0.066 0.000
N84.1 Polyp of cervix uteri
0.934 0.066 0.000
R30-R39 Symptoms and signs involving the urinary system
0.932 0.068 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.930 0.070 0.000
C15-C26 Malignant neoplasms of digestive organs
0.926 0.074 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.923 0.077 0.000
M20.5 Other deformities of toe(s) (acquired)
0.922 0.078 0.000
R33 Retention of urine
0.921 0.079 0.000
N80 Endometriosis
0.920 0.080 0.000
C50 Malignant neoplasm of breast
0.917 0.083 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.917 0.083 0.000
Z87 Personal history of other diseases and conditions
0.913 0.087 0.000
C34 Malignant neoplasm of bronchus and lung
0.912 0.088 0.000
H30-H36 Disorders of choroid and retina
0.911 0.089 0.000
N18.9 Chronic renal failure, unspecified
0.910 0.090 0.000
M80 Osteoporosis with pathological fracture
0.907 0.093 0.000
R51 Headache
0.906 0.094 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.904 0.096 0.000
N18.3 Chronic kidney disease, stage 3
0.903 0.097 0.000
O63 Long labour
0.902 0.098 0.000
I83 Varicose veins of lower extremities
0.900 0.100 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.898 0.102 0.000
R01 Cardiac murmurs and other cardiac sounds
0.895 0.105 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.894 0.106 0.000
N00-N08 Glomerular diseases
0.891 0.109 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.889 0.111 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.887 0.113 0.000
R00 Abnormalities of heart beat
0.886 0.114 0.000
H33 Retinal detachments and breaks
0.883 0.117 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.879 0.121 0.000
Chapter I Certain infectious and parasitic diseases
0.879 0.121 0.000
M23 Internal derangement of knee
0.878 0.122 0.000
N86 Erosion and ectropion of cervix uteri
0.877 0.123 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.875 0.125 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.875 0.125 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.874 0.126 0.000
Z93 Artificial opening status
0.872 0.128 0.000
R04 Haemorrhage from respiratory passages
0.871 0.129 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.865 0.135 0.000
N81 Female genital prolapse
0.864 0.136 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.856 0.144 0.000
M81 Osteoporosis without pathological fracture
0.855 0.145 0.000
O63.1 Prolonged second stage (of labour)
0.854 0.146 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.853 0.147 0.000
R00.0 Tachycardia, unspecified
0.852 0.148 0.000
N18.0 End-stage renal disease
0.852 0.148 0.000
M20.4 Other hammer toe(s) (acquired)
0.851 0.149 0.000
C20 Malignant neoplasm of rectum
0.850 0.150 0.000
R26 Abnormalities of gait and mobility
0.849 0.151 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.848 0.152 0.000
M65-M68 Disorders of synovium and tendon
0.848 0.152 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.847 0.153 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.847 0.153 0.000
C34.1 Upper lobe, bronchus or lung
0.845 0.155 0.000
Chapter XX External causes of morbidity and mortality
0.843 0.157 0.000
C50.9 Breast, unspecified
0.843 0.157 0.000
D00-D09 In situ neoplasms
0.840 0.160 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.839 0.161 0.000
N32.8 Other specified disorders of bladder
0.836 0.164 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.836 0.164 0.000
T51 Toxic effect of alcohol
0.835 0.165 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.833 0.167 0.000
O80-O84 Delivery
0.831 0.169 0.000
N95 Menopausal and other perimenopausal disorders
0.831 0.169 0.000
R01.1 Cardiac murmur, unspecified
0.831 0.169 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.827 0.173 0.000
N32.0 Bladder-neck obstruction
0.826 0.174 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.822 0.178 0.000
H43-H45 Disorders of vitreous body and globe
0.819 0.181 0.000
M84 Disorders of continuity of bone
0.817 0.183 0.000
Z87.1 Personal history of diseases of the digestive system
0.817 0.183 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.816 0.184 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.814 0.185 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.813 0.187 0.000
Z94 Transplanted organ and tissue status
0.812 0.188 0.000
N10-N16 Renal tubulo-interstitial diseases
0.810 0.190 0.000
M86-M90 Other osteopathies
0.809 0.191 0.000
N80.8 Other endometriosis
0.808 0.192 0.000
M20.1 Hallux valgus (acquired)
0.807 0.193 0.000
H33.0 Retinal detachment with retinal break
0.806 0.194 0.000
I60-I69 Cerebrovascular diseases
0.806 0.194 0.000
C34.9 Bronchus or lung, unspecified
0.805 0.195 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.805 0.195 0.000
I85 Oesophageal varices
0.804 0.196 0.000
M40-M43 Deforming dorsopathies
0.803 0.197 0.000
J30-J39 Other diseases of upper respiratory tract
0.802 0.198 0.000
N36 Other disorders of urethra
0.801 0.199 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.798 0.202 0.000
R42 Dizziness and giddiness
0.797 0.203 0.000
N19 Unspecified renal failure
0.796 0.204 0.000
N32.9 Bladder disorder, unspecified
0.796 0.204 0.000
N81.1 Cystocele
0.795 0.205 0.000
E20-E35 Disorders of other endocrine glands
0.795 0.205 0.000
Z91.5 Personal history of self-harm
0.794 0.206 0.000
I80 Phlebitis and thrombophlebitis
0.793 0.207 0.000
N18.5 Chronic kidney disease, stage 5
0.793 0.207 0.000
M21 Other acquired deformities of limbs
0.792 0.208 0.000
R69 Unknown and unspecified causes of morbidity
0.790 0.210 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.788 0.212 0.000
T51.0 Ethanol
0.787 0.213 0.000
N30 Cystitis
0.785 0.215 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.784 0.215 0.000
R02 Gangrene, not elsewhere classified
0.784 0.216 0.000
R06 Abnormalities of breathing
0.784 0.216 0.000
J95-J99 Other diseases of the respiratory system
0.784 0.216 0.000
J18.9 Pneumonia, unspecified
0.783 0.217 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.783 0.217 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.783 0.217 0.000
Z99.2 Dependence on renal dialysis
0.781 0.219 0.000
M23.3 Other meniscus derangements
0.777 0.223 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.777 0.223 0.000
R39 Other symptoms and signs involving the urinary system
0.776 0.224 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.224 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.776 0.224 0.000
A30-A49 Other bacterial diseases
0.776 0.224 0.000
H53-H54 Visual disturbances and blindness
0.774 0.226 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.772 0.228 0.000
C44 Other malignant neoplasms of skin
0.769 0.231 0.000
H33.2 Serous retinal detachment
0.769 0.231 0.000
M85 Other disorders of bone density and structure
0.768 0.232 0.000
J00-J06 Acute upper respiratory infections
0.768 0.232 0.000
M81.9 Osteoporosis, unspecified
0.766 0.234 0.000
T39.1 4-Aminophenol derivatives
0.765 0.235 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.765 0.235 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.763 0.237 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.763 0.237 0.000
R04.0 Epistaxis
0.762 0.238 0.000
H34 Retinal vascular occlusions
0.762 0.238 0.000
N80.9 Endometriosis, unspecified
0.762 0.238 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.762 0.238 0.000
N83.0 Follicular cyst of ovary
0.761 0.239 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.760 0.240 0.000
N80.3 Endometriosis of pelvic peritoneum
0.760 0.240 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.759 0.241 0.000
C50.3 Lower-inner quadrant of breast
0.758 0.242 0.000
R53 Malaise and fatigue
0.758 0.242 0.000
Z96 Presence of other functional implants
0.756 0.244 0.000
R45 Symptoms and signs involving emotional state
0.756 0.244 0.000
T66-T78 Other and unspecified effects of external causes
0.756 0.244 0.000
I87 Other disorders of veins
0.755 0.245 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.754 0.245 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.753 0.247 0.000
T93 Sequelae of injuries of lower limb
0.752 0.248 0.000
D05 Carcinoma in situ of breast
0.747 0.253 0.000
Z93.3 Colostomy status
0.747 0.253 0.000
N92.4 Excessive bleeding in the premenopausal period
0.747 0.253 0.000
Z92 Personal history of medical treatment
0.746 0.254 0.000
N83.2 Other and unspecified ovarian cysts
0.746 0.254 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.744 0.256 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.744 0.256 0.000
C44.1 Skin of eyelid, including canthus
0.743 0.257 0.000
M67 Other disorders of synovium and tendon
0.742 0.258 0.000
Z91.6 Personal history of other physical trauma
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
C18 Malignant neoplasm of colon
0.741 0.259 0.000
R41.0 Disorientation, unspecified
0.741 0.259 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
N92.3 Ovulation bleeding
0.739 0.261 0.000
J90-J94 Other diseases of pleura
0.739 0.261 0.000
T90 Sequelae of injuries of head
0.737 0.263 0.000
O63.9 Long labour, unspecified
0.737 0.263 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.737 0.263 0.000
N99-N99 Other disorders of the genitourinary system
0.736 0.264 0.000
I05-I09 Chronic rheumatic heart diseases
0.734 0.266 0.000
C50.4 Upper-outer quadrant of breast
0.733 0.266 0.000
N03 Chronic nephritic syndrome
0.732 0.268 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.732 0.268 0.000
J18.0 Bronchopneumonia, unspecified
0.731 0.268 0.000
S00-S09 Injuries to the head
0.730 0.270 0.000
C50.2 Upper-inner quadrant of breast
0.729 0.271 0.000
N60-N64 Disorders of breast
0.728 0.272 0.000
O80 Single spontaneous delivery
0.728 0.272 0.000
N18.4 Chronic kidney disease, stage 4
0.727 0.273 0.000
R54 Senility
0.726 0.274 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.726 0.274 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.725 0.275 0.000
N25-N29 Other disorders of kidney and ureter
0.725 0.275 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.276 0.000
N95.0 Postmenopausal bleeding
0.723 0.277 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.719 0.281 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.718 0.282 0.000
Z94.0 Kidney transplant status
0.718 0.282 0.000
I86 Varicose veins of other sites
0.718 0.282 0.000
Z93.2 Ileostomy status
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
S60-S69 Injuries to the wrist and hand
0.716 0.284 0.000
N40-N51 Diseases of male genital organs
0.716 0.284 0.000
N98 Complications associated with artificial fertilisation
0.716 0.284 0.000
N91 Absent, scanty and rare menstruation
0.716 0.284 0.000
N82 Fistulae involving female genital tract
0.716 0.284 0.000
N96 Habitual aborter
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.715 0.285 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.713 0.287 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.713 0.287 0.000
R52 Pain, not elsewhere classified
0.713 0.287 0.000
Chapter VI Diseases of the nervous system
0.712 0.288 0.000
M20.2 Hallux rigidus
0.712 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.288 0.000
N32.3 Diverticulum of bladder
0.711 0.289 0.000
Z86 Personal history of certain other diseases
0.711 0.289 0.000
N13 Obstructive and reflux uropathy
0.711 0.289 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M34 Systemic sclerosis
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
Z87.0 Personal history of diseases of the respiratory system
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.708 0.292 0.000
J17 Pneumonia in diseases classified elsewhere
0.707 0.293 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.707 0.293 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.707 0.293 0.000
J12 Viral pneumonia, not elsewhere classified
0.707 0.293 0.000
J11 Influenza, virus not identified
0.707 0.293 0.000
J10 Influenza due to identified influenza virus
0.707 0.293 0.000
J14 Pneumonia due to Haemophilus influenzae
0.707 0.293 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.707 0.293 0.000
J09 Influenza due to certain identified influenza virus
0.707 0.293 0.000
M20.0 Deformity of finger(s)
0.707 0.293 0.000
J60-J70 Lung diseases due to external agents
0.707 0.293 0.000
N37 Urethral disorders in diseases classified elsewhere
0.704 0.296 0.000
N34 Urethritis and urethral syndrome
0.704 0.296 0.000
N33 Bladder disorders in diseases classified elsewhere
0.704 0.296 0.000
R30 Pain associated with micturition
0.704 0.296 0.000
I63 Cerebral infarction
0.704 0.296 0.000
J18.8 Other pneumonia, organism unspecified
0.704 0.296 0.000
J18.2 Hypostatic pneumonia, unspecified
0.704 0.296 0.000
N18.8 Other chronic renal failure
0.704 0.296 0.000
N18.2 Chronic kidney disease, stage 2
0.704 0.296 0.000
N18.1 Chronic kidney disease, stage 1
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.703 0.297 0.000
C50.5 Lower-outer quadrant of breast
0.703 0.297 0.000
E00-E07 Disorders of thyroid gland
0.703 0.297 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.703 0.297 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.703 0.297 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.703 0.297 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.703 0.297 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.703 0.297 0.000
M83 Adult osteomalacia
0.702 0.298 0.000
M82 Osteoporosis in diseases classified elsewhere
0.702 0.298 0.000
C34.3 Lower lobe, bronchus or lung
0.701 0.298 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.701 0.299 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.701 0.299 0.000
Z99.3 Dependence on wheelchair
0.701 0.299 0.000
M20.3 Other deformity of hallux (acquired)
0.700 0.300 0.000
O85-O92 Complications predominantly related to the puerperium
0.700 0.300 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.699 0.301 0.000
C50.1 Central portion of breast
0.698 0.302 0.000
T42.4 Benzodiazepines
0.698 0.302 0.000
M31 Other necrotising vasculopathies
0.698 0.302 0.000
Z97 Presence of other devices
0.697 0.303 0.000
Z89 Acquired absence of limb
0.697 0.303 0.000
Z84 Family history of other conditions
0.697 0.303 0.000
Z81 Family history of mental and behavioural disorders
0.697 0.303 0.000
M50-M54 Other dorsopathies
0.697 0.303 0.000
H33.3 Retinal breaks without detachment
0.696 0.304 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.696 0.304 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.304 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.696 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
T36 Poisoning by systemic antibiotics
0.696 0.304 0.000
R05 Cough
0.693 0.307 0.000
N39 Other disorders of urinary system
0.693 0.307 0.000
M70-M79 Other soft tissue disorders
0.693 0.307 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.693 0.307 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.691 0.309 0.000
O47 False labour
0.690 0.310 0.000
B35-B49 Mycoses
0.690 0.310 0.000
R41.3 Other amnesia
0.690 0.310 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.690 0.310 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.690 0.310 0.000
H33.5 Other retinal detachments
0.690 0.310 0.000
N05 Unspecified nephritic syndrome
0.688 0.312 0.000
R04.2 Haemoptysis
0.687 0.313 0.000
T40.2 Other opioids
0.687 0.313 0.000
R46 Symptoms and signs involving appearance and behaviour
0.687 0.313 0.000
R43 Disturbances of smell and taste
0.687 0.313 0.000
M35 Other systemic involvement of connective tissue
0.686 0.314 0.000
N92.5 Other specified irregular menstruation
0.685 0.315 0.000
N92.2 Excessive menstruation at puberty
0.685 0.315 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.685 0.315 0.000
R40 Somnolence, stupor and coma
0.685 0.315 0.000
C16 Malignant neoplasm of stomach
0.684 0.316 0.000
M25 Other joint disorders, not elsewhere classified
0.684 0.316 0.000
Z99.1 Dependence on respirator
0.684 0.316 0.000
C43 Malignant melanoma of skin
0.684 0.316 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.684 0.316 0.000
N04 Nephrotic syndrome
0.683 0.316 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.683 0.317 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.682 0.318 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.681 0.319 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.680 0.320 0.000
H36 Retinal disorders in diseases classified elsewhere
0.679 0.321 0.000
N32.4 Rupture of bladder, nontraumatic
0.679 0.321 0.000
N32.2 Vesical fistula, not elsewhere classified
0.679 0.321 0.000
N32.1 Vesicointestinal fistula
0.679 0.321 0.000
N84.9 Polyp of female genital tract, unspecified
0.679 0.321 0.000
N84.8 Polyp of other parts of female genital tract
0.679 0.321 0.000
N84.3 Polyp of vulva
0.679 0.321 0.000
N84.2 Polyp of vagina
0.679 0.321 0.000
C64-C68 Malignant neoplasms of urinary tract
0.679 0.321 0.000
Z80 Family history of malignant neoplasm
0.678 0.322 0.000
D80-D89 Certain disorders involving the immune mechanism
0.678 0.322 0.000
N89 Other noninflammatory disorders of vagina
0.678 0.322 0.000
M23.5 Chronic instability of knee
0.677 0.323 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.676 0.323 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.676 0.323 0.000
C32 Malignant neoplasm of larynx
0.676 0.323 0.000
C31 Malignant neoplasm of accessory sinuses
0.676 0.323 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.676 0.323 0.000
C37 Malignant neoplasm of thymus
0.676 0.323 0.000
C33 Malignant neoplasm of trachea
0.676 0.323 0.000
H55-H59 Other disorders of eye and adnexa
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
H10-H13 Disorders of conjunctiva
0.676 0.324 0.000
H43 Disorders of vitreous body
0.676 0.324 0.000
N97 Female infertility
0.675 0.325 0.000
I00-I02 Acute rheumatic fever
0.675 0.325 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.675 0.325 0.000
O74 Complications of anaesthesia during labour and delivery
0.675 0.325 0.000
O73 Retained placenta and membranes, without haemorrhage
0.675 0.325 0.000
O71 Other obstetric trauma
0.675 0.325 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.675 0.325 0.000
O66 Other obstructed labour
0.675 0.325 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.675 0.325 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.675 0.325 0.000
O62 Abnormalities of forces of labour
0.675 0.325 0.000
O61 Failed induction of labour
0.675 0.325 0.000
O60 Preterm delivery
0.675 0.325 0.000
W00-W19 Falls
0.675 0.325 0.000
H44 Disorders of globe
0.675 0.325 0.000
C25 Malignant neoplasm of pancreas
0.674 0.326 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.674 0.326 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.673 0.327 0.000
R09.1 Pleurisy
0.673 0.327 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.673 0.327 0.000
O63.0 Prolonged first stage (of labour)
0.672 0.328 0.000
N36.2 Urethral caruncle
0.672 0.328 0.000
T81 Complications of procedures, not elsewhere classified
0.671 0.329 0.000
A41 Other septicaemia
0.671 0.329 0.000
R68 Other general symptoms and signs
0.670 0.330 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.670 0.330 0.000
R62 Lack of expected normal physiological development
0.670 0.330 0.000
R57 Shock, not elsewhere classified
0.670 0.330 0.000
R64 Cachexia
0.670 0.330 0.000
R58 Haemorrhage, not elsewhere classified
0.670 0.330 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.670 0.330 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.669 0.331 0.000
Z86.4 Personal history of psychoactive substance abuse
0.669 0.331 0.000
R36 Urethral discharge
0.668 0.332 0.000
R34 Anuria and oliguria
0.668 0.332 0.000
C51-C58 Malignant neoplasms of female genital organs
0.668 0.332 0.000
M24 Other specific joint derangements
0.667 0.333 0.000
I88 Nonspecific lymphadenitis
0.667 0.333 0.000
I82 Other venous embolism and thrombosis
0.667 0.333 0.000
I81 Portal vein thrombosis
0.667 0.333 0.000
Z29 Need for other prophylactic measures
0.667 0.333 0.000
M67.8 Other specified disorders of synovium and tendon
0.666 0.334 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.666 0.334 0.000
Z74 Problems related to care-provider dependency
0.666 0.334 0.000
I85.9 Oesophageal varices without bleeding
0.666 0.334 0.000
Z93.6 Other artificial openings of urinary tract status
0.665 0.335 0.000
M23.4 Loose body in knee
0.664 0.336 0.000
N81.9 Female genital prolapse, unspecified
0.664 0.336 0.000
N45 Orchitis and epididymitis
0.664 0.336 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.664 0.336 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.664 0.336 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.664 0.336 0.000
C21 Malignant neoplasm of anus and anal canal
0.664 0.336 0.000
C17 Malignant neoplasm of small intestine
0.664 0.336 0.000
C23 Malignant neoplasm of gallbladder
0.664 0.336 0.000
O46.9 Antepartum haemorrhage, unspecified
0.664 0.336 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.663 0.337 0.000
M45-M49 Spondylopathies
0.663 0.337 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.662 0.338 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.661 0.338 0.000
M22 Disorders of patella
0.660 0.339 0.000
S50-S59 Injuries to the elbow and forearm
0.660 0.339 0.000
N80.6 Endometriosis in cutaneous scar
0.660 0.340 0.000
N80.5 Endometriosis of intestine
0.660 0.340 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.660 0.340 0.000
N80.2 Endometriosis of Fallopian tube
0.660 0.340 0.000
Z83 Family history of other specific disorders
0.658 0.342 0.000
Z99.8 Dependence on other enabling machines and devices
0.658 0.342 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.658 0.342 0.000
C50.6 Axillary tail of breast
0.658 0.342 0.000
C50.0 Nipple and areola
0.658 0.342 0.000
N81.2 Incomplete uterovaginal prolapse
0.658 0.342 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
T87 Complications peculiar to reattachment and amputation
0.657 0.343 0.000
T86 Failure and rejection of transplanted organs and tissues
0.657 0.343 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.657 0.343 0.000
O48 Prolonged pregnancy
0.657 0.343 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.656 0.344 0.000
E28 Ovarian dysfunction
0.656 0.344 0.000
I85.0 Oesophageal varices with bleeding
0.656 0.344 0.000
H34.8 Other retinal vascular occlusions
0.655 0.344 0.000
R56 Convulsions, not elsewhere classified
0.655 0.345 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.654 0.345 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.654 0.345 0.000
C34.8 Overlapping lesion of bronchus and lung
0.654 0.346 0.000
C34.2 Middle lobe, bronchus or lung
0.654 0.346 0.000
C34.0 Main bronchus
0.654 0.346 0.000
R06.0 Dyspnoea
0.654 0.346 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.653 0.346 0.000
H31 Other disorders of choroid
0.653 0.346 0.000
H30 Chorioretinal inflammation
0.653 0.346 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.653 0.347 0.000
N30.2 Other chronic cystitis
0.653 0.347 0.000
I30-I52 Other forms of heart disease
0.653 0.347 0.000
N87 Dysplasia of cervix uteri
0.652 0.347 0.000
N81.8 Other female genital prolapse
0.652 0.348 0.000
N92.6 Irregular menstruation, unspecified
0.652 0.348 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.652 0.348 0.000
H90-H95 Other disorders of ear
0.652 0.348 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.652 0.348 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.651 0.349 0.000
O70 Perineal laceration during delivery
0.651 0.349 0.000
M80.8 Other osteoporosis with pathological fracture
0.650 0.350 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.650 0.350 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.650 0.350 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.650 0.350 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.650 0.350 0.000
M21.0 Valgus deformity, not elsewhere classified
0.649 0.351 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.649 0.351 0.000
O42 Premature rupture of membranes
0.649 0.351 0.000
T65 Toxic effect of other and unspecified substances
0.648 0.352 0.000
T63 Toxic effect of contact with venomous animals
0.648 0.352 0.000
T62 Toxic effect of other noxious substances eaten as food
0.648 0.352 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.648 0.352 0.000
T60 Toxic effect of pesticides
0.648 0.352 0.000
T59 Toxic effect of other gases, fumes and vapours
0.648 0.352 0.000
T57 Toxic effect of other inorganic substances
0.648 0.352 0.000
T56 Toxic effect of metals
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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