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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78538921
log Bayes Factor = 14.5485
Chromosome 2   position 133,732,518  (GRCh37) Explore rs78538921 on Ensembl!
Variant rs78538921 is part of Cluster X0181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.991 0.009 0.000
I95 Hypotension
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
Chapter VIII Diseases of the ear and mastoid process
0.978 0.022 0.000
I95.9 Hypotension, unspecified
0.976 0.024 0.000
H90-H95 Other disorders of ear
0.975 0.025 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.973 0.027 0.000
H91 Other hearing loss
0.969 0.031 0.000
M75 Shoulder lesions
0.965 0.035 0.000
H91.9 Hearing loss, unspecified
0.964 0.036 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.959 0.041 0.000
J95-J99 Other diseases of the respiratory system
0.958 0.042 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.957 0.043 0.000
Chapter VII Diseases of the eye and adnexa
0.957 0.043 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.955 0.045 0.000
I77 Other disorders of arteries and arterioles
0.952 0.048 0.000
Chapter V Mental and behavioural disorders
0.948 0.052 0.000
Chapter XXI Factors influencing health status and contact with health services
0.947 0.053 0.000
Chapter XX External causes of morbidity and mortality
0.945 0.055 0.000
I60-I69 Cerebrovascular diseases
0.943 0.057 0.000
J30-J39 Other diseases of upper respiratory tract
0.943 0.057 0.000
S00-S09 Injuries to the head
0.936 0.064 0.000
I67 Other cerebrovascular diseases
0.933 0.067 0.000
B35-B49 Mycoses
0.929 0.071 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.921 0.079 0.000
B95-B98 Bacterial, viral and other infectious agents
0.920 0.080 0.000
L40-L45 Papulosquamous disorders
0.919 0.081 0.000
M20-M25 Other joint disorders
0.917 0.083 0.000
M80-M85 Disorders of bone density and structure
0.913 0.087 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.912 0.088 0.000
T93 Sequelae of injuries of lower limb
0.909 0.091 0.000
J00-J06 Acute upper respiratory infections
0.908 0.092 0.000
M75.1 Rotator cuff syndrome
0.900 0.100 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.898 0.102 0.000
I67.9 Cerebrovascular disease, unspecified
0.898 0.102 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.897 0.103 0.000
S80-S89 Injuries to the knee and lower leg
0.896 0.104 0.000
M77 Other enthesopathies
0.894 0.106 0.000
M40-M43 Deforming dorsopathies
0.893 0.107 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.892 0.108 0.000
J20-J22 Other acute lower respiratory infections
0.892 0.108 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.891 0.109 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.888 0.112 0.000
M35 Other systemic involvement of connective tissue
0.884 0.116 0.000
I99 Other and unspecified disorders of circulatory system
0.882 0.118 0.000
H55-H59 Other disorders of eye and adnexa
0.881 0.119 0.000
A30-A49 Other bacterial diseases
0.880 0.120 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.876 0.124 0.000
S70-S79 Injuries to the hip and thigh
0.875 0.125 0.000
L40 Psoriasis
0.874 0.126 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.870 0.130 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.866 0.134 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.863 0.137 0.000
S02 Fracture of skull and facial bones
0.861 0.139 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.861 0.139 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.859 0.141 0.000
M35.3 Polymyalgia rheumatica
0.857 0.143 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.856 0.144 0.000
I77.6 Arteritis, unspecified
0.855 0.145 0.000
T93.2 Sequelae of other fractures of lower limb
0.854 0.146 0.000
M79.0 Rheumatism, unspecified
0.853 0.147 0.000
M05-M14 Inflammatory polyarthropathies
0.847 0.153 0.000
S40-S49 Injuries to the shoulder and upper arm
0.845 0.155 0.000
I74 Arterial embolism and thrombosis
0.844 0.156 0.000
J38.1 Polyp of vocal cord and larynx
0.843 0.157 0.000
J95.8 Other postprocedural respiratory disorders
0.837 0.163 0.000
Z42 Follow-up care involving plastic surgery
0.835 0.165 0.000
H53-H54 Visual disturbances and blindness
0.835 0.165 0.000
L40.9 Psoriasis, unspecified
0.834 0.166 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.831 0.169 0.000
L03 Cellulitis
0.830 0.170 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.829 0.171 0.000
M75.2 Bicipital tendinitis
0.829 0.171 0.000
I77.1 Stricture of artery
0.828 0.172 0.000
B37 Candidiasis
0.826 0.174 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.826 0.174 0.000
J98 Other respiratory disorders
0.824 0.176 0.000
Chapter VI Diseases of the nervous system
0.822 0.178 0.000
M75.3 Calcific tendinitis of shoulder
0.821 0.179 0.000
H93 Other disorders of ear, not elsewhere classified
0.821 0.179 0.000
V20-V29 Motorcycle rider injured in transport accident
0.820 0.180 0.000
M43 Other deforming dorsopathies
0.819 0.181 0.000
S06 Intracranial injury
0.818 0.182 0.000
W00-W19 Falls
0.816 0.184 0.000
J22 Unspecified acute lower respiratory infection
0.816 0.184 0.000
D68 Other coagulation defects
0.815 0.185 0.000
J00 Acute nasopharyngitis [common cold]
0.813 0.187 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.813 0.187 0.000
J39 Other diseases of upper respiratory tract
0.812 0.188 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.812 0.188 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.811 0.189 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.810 0.190 0.000
I67.1 Cerebral aneurysm, nonruptured
0.809 0.191 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.808 0.192 0.000
I73 Other peripheral vascular diseases
0.807 0.193 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.804 0.196 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.802 0.198 0.000
M31 Other necrotising vasculopathies
0.801 0.199 0.000
F30-F39 Mood [affective] disorders
0.801 0.199 0.000
J84 Other interstitial pulmonary diseases
0.796 0.204 0.000
I86 Varicose veins of other sites
0.796 0.204 0.000
T92 Sequelae of injuries of upper limb
0.795 0.205 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.795 0.205 0.000
L50-L54 Urticaria and erythema
0.794 0.206 0.000
M86-M90 Other osteopathies
0.793 0.207 0.000
M72 Fibroblastic disorders
0.792 0.208 0.000
S80 Superficial injury of lower leg
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.209 0.000
M45-M49 Spondylopathies
0.790 0.210 0.000
B65-B83 Helminthiases
0.790 0.210 0.000
M77.4 Metatarsalgia
0.789 0.211 0.000
M81 Osteoporosis without pathological fracture
0.789 0.211 0.000
I80 Phlebitis and thrombophlebitis
0.789 0.211 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.788 0.212 0.000
M71 Other bursopathies
0.787 0.213 0.000
I71 Aortic aneurysm and dissection
0.787 0.213 0.000
I72 Other aneurysm
0.786 0.214 0.000
S70 Superficial injury of hip and thigh
0.784 0.216 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.783 0.217 0.000
I67.2 Cerebral atherosclerosis
0.780 0.220 0.000
Q60-Q64 Congenital malformations of the urinary system
0.779 0.221 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.779 0.221 0.000
B37.0 Candidal stomatitis
0.779 0.221 0.000
Z86.7 Personal history of diseases of the circulatory system
0.778 0.222 0.000
Z86 Personal history of certain other diseases
0.778 0.222 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.778 0.222 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.777 0.223 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.775 0.225 0.000
I70 Atherosclerosis
0.774 0.226 0.000
T40.2 Other opioids
0.774 0.226 0.000
L03.1 Cellulitis of other parts of limb
0.773 0.227 0.000
H53 Visual disturbances
0.772 0.228 0.000
A49 Bacterial infection of unspecified site
0.770 0.230 0.000
D60-D64 Aplastic and other anaemias
0.770 0.230 0.000
I10-I15 Hypertensive diseases
0.769 0.231 0.000
L05 Pilonidal cyst
0.769 0.231 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.767 0.233 0.000
D80-D89 Certain disorders involving the immune mechanism
0.767 0.233 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.766 0.233 0.000
I77.8 Other specified disorders of arteries and arterioles
0.766 0.234 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.765 0.234 0.000
D55-D59 Haemolytic anaemias
0.764 0.236 0.000
M75.4 Impingement syndrome of shoulder
0.764 0.236 0.000
J81 Pulmonary oedema
0.764 0.236 0.000
S02.2 Fracture of nasal bones
0.763 0.237 0.000
J98.8 Other specified respiratory disorders
0.760 0.240 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
F17.1 Harmful use
0.759 0.241 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.758 0.242 0.000
B44 Aspergillosis
0.756 0.244 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.756 0.244 0.000
J38.7 Other diseases of larynx
0.756 0.244 0.000
H57 Other disorders of eye and adnexa
0.755 0.245 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.755 0.245 0.000
F17.2 Dependence syndrome
0.755 0.245 0.000
M43.1 Spondylolisthesis
0.754 0.246 0.000
M50-M54 Other dorsopathies
0.754 0.246 0.000
I95.2 Hypotension due to drugs
0.751 0.249 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.751 0.249 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.750 0.250 0.000
S81 Open wound of lower leg
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.746 0.254 0.000
H92 Otalgia and effusion of ear
0.746 0.254 0.000
M34 Systemic sclerosis
0.746 0.254 0.000
X60-X84 Intentional self-harm
0.746 0.254 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.745 0.255 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.745 0.255 0.000
F80-F89 Disorders of psychological development
0.744 0.256 0.000
L03.0 Cellulitis of finger and toe
0.742 0.258 0.000
I67.8 Other specified cerebrovascular diseases
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.742 0.258 0.000
Z40 Prophylactic surgery
0.742 0.258 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.741 0.259 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.740 0.260 0.000
M79.7 Fibromyalgia
0.739 0.261 0.000
F31 Bipolar affective disorder
0.738 0.262 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.738 0.262 0.000
Q00-Q07 Congenital malformations of the nervous system
0.737 0.263 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.736 0.264 0.000
M06 Other rheumatoid arthritis
0.735 0.265 0.000
Z90.1 Acquired absence of breast(s)
0.734 0.266 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.734 0.266 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.734 0.266 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.268 0.000
T86 Failure and rejection of transplanted organs and tissues
0.731 0.269 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.730 0.270 0.000
S20-S29 Injuries to the thorax
0.730 0.270 0.000
M54 Dorsalgia
0.729 0.271 0.000
Q50-Q56 Congenital malformations of genital organs
0.728 0.272 0.000
S05 Injury of eye and orbit
0.728 0.272 0.000
Z47 Other orthopaedic follow-up care
0.727 0.273 0.000
M46 Other inflammatory spondylopathies
0.727 0.273 0.000
L89 Decubitus ulcer
0.726 0.274 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.725 0.275 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
J32 Chronic sinusitis
0.725 0.275 0.000
J37 Chronic laryngitis and laryngotracheitis
0.724 0.276 0.000
M77.1 Lateral epicondylitis
0.724 0.276 0.000
J35 Chronic diseases of tonsils and adenoids
0.724 0.276 0.000
H55 Nystagmus and other irregular eye movements
0.723 0.277 0.000
T39.1 4-Aminophenol derivatives
0.723 0.277 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.722 0.277 0.000
A40 Streptococcal septicaemia
0.723 0.277 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.722 0.278 0.000
B49 Unspecified mycosis
0.721 0.279 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.720 0.280 0.000
S02.4 Fracture of malar and maxillary bones
0.720 0.280 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.720 0.280 0.000
J03 Acute tonsillitis
0.720 0.280 0.000
S09 Other and unspecified injuries of head
0.719 0.281 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.718 0.282 0.000
S90-S99 Injuries to the ankle and foot
0.718 0.282 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
J38.5 Laryngeal spasm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H53.0 Amblyopia ex anopsia
0.717 0.283 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.715 0.285 0.000
T93.1 Sequelae of fracture of femur
0.714 0.285 0.000
M84 Disorders of continuity of bone
0.714 0.286 0.000
L50 Urticaria
0.714 0.286 0.000
D68.2 Hereditary deficiency of other clotting factors
0.714 0.286 0.000
M05 Seropositive rheumatoid arthritis
0.713 0.287 0.000
W20-W49 Exposure to inanimate mechanical forces
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.712 0.288 0.000
I86.1 Scrotal varices
0.712 0.288 0.000
T98 Sequelae of other and unspecified effects of external causes
0.712 0.288 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
M79.2 Neuralgia and neuritis, unspecified
0.710 0.289 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.710 0.290 0.000
M54.9 Dorsalgia, unspecified
0.710 0.290 0.000
B35 Dermatophytosis
0.709 0.291 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.709 0.291 0.000
Q80-Q89 Other congenital malformations
0.708 0.292 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.708 0.292 0.000
M85 Other disorders of bone density and structure
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.706 0.294 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.705 0.295 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.705 0.295 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.704 0.296 0.000
I95.8 Other hypotension
0.704 0.296 0.000
I95.0 Idiopathic hypotension
0.704 0.296 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.704 0.296 0.000
M22 Disorders of patella
0.703 0.297 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.702 0.298 0.000
L10-L14 Bullous disorders
0.702 0.298 0.000
S80.9 Superficial injury of lower leg, unspecified
0.701 0.299 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.699 0.301 0.000
H30-H36 Disorders of choroid and retina
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.699 0.301 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.699 0.301 0.000
M31.6 Other giant cell arteritis
0.699 0.301 0.000
M80 Osteoporosis with pathological fracture
0.698 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.697 0.303 0.000
M79.1 Myalgia
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
G62 Other polyneuropathies
0.697 0.303 0.000
I61 Intracerebral haemorrhage
0.696 0.304 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.696 0.304 0.000
M35.1 Other overlap syndromes
0.695 0.305 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
H91.8 Other specified hearing loss
0.694 0.305 0.000
H91.3 Deaf mutism, not elsewhere classified
0.694 0.305 0.000
H91.2 Sudden idiopathic hearing loss
0.694 0.305 0.000
H91.1 Presbycusis
0.694 0.305 0.000
H91.0 Ototoxic hearing loss
0.694 0.305 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.693 0.306 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.693 0.307 0.000
S02.20 Fracture of nasal bones (closed)
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.692 0.308 0.000
M75.9 Shoulder lesion, unspecified
0.692 0.308 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.692 0.308 0.000
D50-D53 Nutritional anaemias
0.690 0.309 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.690 0.310 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.689 0.310 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
S70.0 Contusion of hip
0.687 0.313 0.000
J96 Respiratory failure, not elsewhere classified
0.687 0.313 0.000
S40 Superficial injury of shoulder and upper arm
0.687 0.313 0.000
T95 Sequelae of burns, corrosions and frostbite
0.686 0.314 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.686 0.314 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.686 0.314 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.685 0.315 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.315 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.685 0.315 0.000
H93.9 Disorder of ear, unspecified
0.684 0.316 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
W50-W64 Exposure to animate mechanical forces
0.683 0.317 0.000
I77.5 Necrosis of artery
0.682 0.318 0.000
I77.4 Coeliac artery compression syndrome
0.682 0.318 0.000
I77.3 Arterial fibromuscular dysplasia
0.682 0.318 0.000
I77.2 Rupture of artery
0.682 0.318 0.000
I77.0 Arteriovenous fistula, acquired
0.682 0.318 0.000
T40.4 Other synthetic narcotics
0.682 0.318 0.000
M79.5 Residual foreign body in soft tissue
0.682 0.318 0.000
Chapter XXII Codes for special purposes
0.682 0.318 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.682 0.318 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.682 0.318 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.681 0.319 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.679 0.320 0.000
F70-F79 Mental retardation
0.679 0.320 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.679 0.321 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.678 0.321 0.000
H95.1 Other disorders following mastoidectomy
0.678 0.322 0.000
B15-B19 Viral hepatitis
0.678 0.322 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.678 0.322 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.678 0.322 0.000
L03.8 Cellulitis of other sites
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
Y00-Y09 Assault
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
J39.2 Other diseases of pharynx
0.677 0.323 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.676 0.324 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.676 0.324 0.000
L40.5 Arthropathic psoriasis
0.676 0.324 0.000
I81 Portal vein thrombosis
0.676 0.324 0.000
I85 Oesophageal varices
0.676 0.324 0.000
H04 Disorders of lachrymal system
0.676 0.324 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.676 0.324 0.000
I60 Subarachnoid haemorrhage
0.676 0.324 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.675 0.325 0.000
M24 Other specific joint derangements
0.675 0.325 0.000
T43.2 Other and unspecified antidepressants
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.674 0.326 0.000
W06 Fall involving bed
0.674 0.326 0.000
B37.4 Candidiasis of other urogenital sites
0.673 0.327 0.000
B00 Herpesviral [herpes simplex] infections
0.673 0.327 0.000
J38.0 Paralysis of vocal cords and larynx
0.672 0.327 0.000
W19 Unspecified fall
0.672 0.328 0.000
S08 Traumatic amputation of part of head
0.671 0.329 0.000
S07 Crushing injury of head
0.671 0.329 0.000
S04 Injury of cranial nerves
0.671 0.329 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.671 0.329 0.000
A00-A09 Intestinal infectious diseases
0.671 0.329 0.000
T79-T79 Certain early complications of trauma
0.671 0.329 0.000
L43 Lichen planus
0.671 0.329 0.000
J36 Peritonsillar abscess
0.671 0.329 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.670 0.330 0.000
H53.9 Visual disturbance, unspecified
0.669 0.331 0.000
M81.0 Postmenopausal osteoporosis
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.669 0.331 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.669 0.331 0.000
I67.5 Moyamoya disease
0.669 0.331 0.000
I67.4 Hypertensive encephalopathy
0.669 0.331 0.000
I67.3 Progressive vascular leukoencephalopathy
0.669 0.331 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.669 0.331 0.000
S00 Superficial injury of head
0.669 0.331 0.000
Z29 Need for other prophylactic measures
0.669 0.331 0.000
I65.2 Occlusion and stenosis of carotid artery
0.669 0.331 0.000
A48 Other bacterial diseases, not elsewhere classified
0.668 0.332 0.000
I73.9 Peripheral vascular disease, unspecified
0.668 0.332 0.000
H10-H13 Disorders of conjunctiva
0.668 0.332 0.000
I86.4 Gastric varices
0.667 0.333 0.000
S02.8 Fractures of other skull and facial bones
0.666 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
B48 Other mycoses, not elsewhere classified
0.666 0.334 0.000
B47 Mycetoma
0.666 0.334 0.000
B46 Zygomycosis
0.666 0.334 0.000
B45 Cryptococcosis
0.666 0.334 0.000
B43 Chromomycosis and phaeomycotic abscess
0.666 0.334 0.000
B42 Sporotrichosis
0.666 0.334 0.000
B41 Paracoccidioidomycosis
0.666 0.334 0.000
B40 Blastomycosis
0.666 0.334 0.000
B39 Histoplasmosis
0.666 0.334 0.000
B38 Coccidioidomycosis
0.666 0.334 0.000
B36 Other superficial mycoses
0.666 0.334 0.000
V23.4 Driver injured in traffic accident
0.666 0.334 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.665 0.335 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
J04 Acute laryngitis and tracheitis
0.665 0.335 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.665 0.335 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.665 0.335 0.000
T91 Sequelae of injuries of neck and trunk
0.664 0.336 0.000
Z98 Other postsurgical states
0.664 0.336 0.000
T92.1 Sequelae of fracture of arm
0.664 0.336 0.000
L05.9 Pilonidal cyst without abscess
0.664 0.336 0.000
I78 Diseases of capillaries
0.662 0.337 0.000
T90 Sequelae of injuries of head
0.661 0.339 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.661 0.339 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.661 0.339 0.000
I11 Hypertensive heart disease
0.661 0.339 0.000
M79.9 Soft tissue disorder, unspecified
0.660 0.340 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.660 0.340 0.000
M79.3 Panniculitis, unspecified
0.660 0.340 0.000
G62.9 Polyneuropathy, unspecified
0.660 0.340 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.660 0.340 0.000
Chapter XIV Diseases of the genitourinary system
0.660 0.340 0.000
L44 Other papulosquamous disorders
0.659 0.341 0.000
L41 Parapsoriasis
0.659 0.341 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.659 0.341 0.000
L42 Pityriasis rosea
0.659 0.341 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.658 0.342 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.657 0.342 0.000
M33 Dermatopolymyositis
0.657 0.342 0.000
M32 Systemic lupus erythematosus
0.657 0.342 0.000
M30 Polyarteritis nodosa and related conditions
0.657 0.342 0.000
Y43 Primarily systemic agents
0.657 0.343 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.657 0.343 0.000
H90 Conductive and sensorineural hearing loss
0.657 0.343 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.657 0.343 0.000
M21 Other acquired deformities of limbs
0.656 0.343 0.000
J98.4 Other disorders of lung
0.656 0.344 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.656 0.344 0.000
I62 Other nontraumatic intracranial haemorrhage
0.656 0.344 0.000
Z63 Other problems related to primary support group, including family circumstances
0.656 0.344 0.000
M83 Adult osteomalacia
0.654 0.346 0.000
M82 Osteoporosis in diseases classified elsewhere
0.654 0.346 0.000
H43-H45 Disorders of vitreous body and globe
0.654 0.346 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.653 0.347 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.652 0.348 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.652 0.348 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.652 0.348 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.652 0.348 0.000
T93.0 Sequelae of open wound of lower limb
0.652 0.348 0.000
T87 Complications peculiar to reattachment and amputation
0.652 0.348 0.000
M77.0 Medial epicondylitis
0.652 0.348 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.652 0.348 0.000
J39.8 Other specified diseases of upper respiratory tract
0.652 0.348 0.000
D68.5 Primary Thrombophilia
0.652 0.348 0.000
F33 Recurrent depressive disorder
0.651 0.349 0.000
J01 Acute sinusitis
0.651 0.349 0.000
D68.9 Coagulation defect, unspecified
0.651 0.349 0.000
G61 Inflammatory polyneuropathy
0.650 0.350 0.000
B01 Varicella [chickenpox]
0.650 0.350 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
L93 Lupus erythematosus
0.649 0.351 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.649 0.351 0.000
I12 Hypertensive renal disease
0.649 0.351 0.000
H92.0 Otalgia
0.649 0.351 0.000
H20 Iridocyclitis
0.648 0.352 0.000
S72 Fracture of femur
0.648 0.352 0.000
Z54 Convalescence
0.647 0.352 0.000
I05-I09 Chronic rheumatic heart diseases
0.647 0.353 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.647 0.353 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.646 0.354 0.000
Q61 Cystic kidney disease
0.646 0.354 0.000
Z53.9 Procedure not carried out, unspecified reason
0.646 0.354 0.000
S50-S59 Injuries to the elbow and forearm
0.645 0.354 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.645 0.355 0.000
S81.8 Open wound of other parts of lower leg
0.645 0.355 0.000
G70-G73 Diseases of myoneural junction and muscle
0.645 0.355 0.000
B80 Enterobiasis
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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