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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78566849
log Bayes Factor = 16.9908
Chromosome 5   position 156,916,452  (GRCh37) Explore rs78566849 on Ensembl!
Variant rs78566849 is part of Cluster X0221

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.996 0.004 0.000
J45 Asthma
0.996 0.004 0.000
J45.9 Asthma, unspecified
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
A30-A49 Other bacterial diseases
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
A41 Other septicaemia
0.984 0.016 0.000
I44 Atrioventricular and left bundle-branch block
0.979 0.021 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.978 0.022 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
Q60-Q64 Congenital malformations of the urinary system
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
M20-M25 Other joint disorders
0.973 0.027 0.000
J30-J39 Other diseases of upper respiratory tract
0.970 0.030 0.000
S50-S59 Injuries to the elbow and forearm
0.969 0.031 0.000
S60-S69 Injuries to the wrist and hand
0.965 0.035 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.963 0.037 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.962 0.038 0.000
I44.0 Atrioventricular block, first degree
0.960 0.040 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.959 0.041 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.958 0.042 0.000
Q61 Cystic kidney disease
0.957 0.043 0.000
J09-J18 Influenza and pneumonia
0.956 0.044 0.000
D70 Agranulocytosis
0.954 0.046 0.000
Y43 Primarily systemic agents
0.952 0.048 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.950 0.050 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.947 0.053 0.000
I35 Nonrheumatic aortic valve disorders
0.941 0.059 0.000
H43-H45 Disorders of vitreous body and globe
0.937 0.063 0.000
Y43.3 Other antineoplastic drugs
0.937 0.063 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.932 0.068 0.000
J34 Other disorders of nose and nasal sinuses
0.930 0.070 0.000
J33 Nasal polyp
0.929 0.071 0.000
I95 Hypotension
0.928 0.072 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.928 0.072 0.000
H10-H13 Disorders of conjunctiva
0.926 0.074 0.000
S52 Fracture of forearm
0.923 0.077 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.921 0.079 0.000
G62 Other polyneuropathies
0.918 0.082 0.000
B35-B49 Mycoses
0.912 0.088 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.906 0.094 0.000
T90 Sequelae of injuries of head
0.900 0.100 0.000
I38 Endocarditis, valve unspecified
0.899 0.101 0.000
G62.9 Polyneuropathy, unspecified
0.898 0.102 0.000
M91-M94 Chondropathies
0.897 0.103 0.000
S52.5 Fracture of lower end of radius
0.897 0.103 0.000
Y84.8 Other medical procedures
0.894 0.106 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.893 0.107 0.000
M22 Disorders of patella
0.891 0.109 0.000
A41.9 Septicaemia, unspecified
0.888 0.112 0.000
J47 Bronchiectasis
0.888 0.112 0.000
I46 Cardiac arrest
0.887 0.113 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.887 0.113 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.881 0.119 0.000
J44 Other chronic obstructive pulmonary disease
0.881 0.119 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.880 0.120 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.878 0.122 0.000
Q61.0 Congenital single renal cyst
0.877 0.123 0.000
J42 Unspecified chronic bronchitis
0.877 0.123 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
J18 Pneumonia, organism unspecified
0.874 0.126 0.000
Q80-Q89 Other congenital malformations
0.873 0.127 0.000
I35.0 Aortic (valve) stenosis
0.873 0.127 0.000
S52.50 Fracture of lower end of radius (closed)
0.872 0.128 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.872 0.128 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.871 0.129 0.000
H11 Other disorders of conjunctiva
0.870 0.130 0.000
Q61.3 Polycystic kidney, unspecified
0.868 0.132 0.000
M34 Systemic sclerosis
0.867 0.133 0.000
S90-S99 Injuries to the ankle and foot
0.866 0.134 0.000
I34 Nonrheumatic mitral valve disorders
0.866 0.134 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.864 0.136 0.000
H44 Disorders of globe
0.863 0.137 0.000
J60-J70 Lung diseases due to external agents
0.863 0.137 0.000
I27 Other pulmonary heart diseases
0.862 0.138 0.000
T66-T78 Other and unspecified effects of external causes
0.861 0.139 0.000
I44.1 Atrioventricular block, second degree
0.859 0.141 0.000
S60 Superficial injury of wrist and hand
0.858 0.142 0.000
M24 Other specific joint derangements
0.855 0.145 0.000
I95.9 Hypotension, unspecified
0.853 0.147 0.000
M94 Other disorders of cartilage
0.852 0.148 0.000
J18.9 Pneumonia, unspecified
0.848 0.152 0.000
J33.8 Other polyp of sinus
0.848 0.152 0.000
I95.2 Hypotension due to drugs
0.846 0.154 0.000
B37 Candidiasis
0.844 0.156 0.000
S64 Injury of nerves at wrist and hand level
0.843 0.157 0.000
J33.0 Polyp of nasal cavity
0.838 0.162 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.835 0.165 0.000
Chapter VIII Diseases of the ear and mastoid process
0.833 0.167 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.832 0.168 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.827 0.173 0.000
M25 Other joint disorders, not elsewhere classified
0.826 0.174 0.000
D75 Other diseases of blood and blood-forming organs
0.824 0.176 0.000
A49 Bacterial infection of unspecified site
0.823 0.177 0.000
G30-G32 Other degenerative diseases of the nervous system
0.823 0.177 0.000
M22.8 Other disorders of patella
0.823 0.177 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.821 0.179 0.000
H18 Other disorders of cornea
0.821 0.179 0.000
W20-W49 Exposure to inanimate mechanical forces
0.820 0.180 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.820 0.180 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.819 0.181 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.817 0.183 0.000
Q61.2 Polycystic kidney, adult type
0.817 0.183 0.000
Y84.0 Cardiac catheterisation
0.817 0.183 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.817 0.183 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.814 0.186 0.000
I49 Other cardiac arrhythmias
0.813 0.187 0.000
H25-H28 Disorders of lens
0.813 0.187 0.000
T86 Failure and rejection of transplanted organs and tissues
0.813 0.187 0.000
I46.9 Cardiac arrest, unspecified
0.812 0.188 0.000
H44.2 Degenerative myopia
0.811 0.189 0.000
G51 Facial nerve disorders
0.811 0.189 0.000
J34.2 Deviated nasal septum
0.809 0.191 0.000
Y40 Systemic antibiotics
0.808 0.192 0.000
S62 Fracture at wrist and hand level
0.806 0.194 0.000
M21 Other acquired deformities of limbs
0.806 0.194 0.000
G63.2 Diabetic polyneuropathy
0.806 0.194 0.000
Chapter XXII Codes for special purposes
0.806 0.194 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.804 0.196 0.000
A00-A09 Intestinal infectious diseases
0.802 0.198 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.801 0.199 0.000
M35 Other systemic involvement of connective tissue
0.800 0.200 0.000
J20-J22 Other acute lower respiratory infections
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
H20 Iridocyclitis
0.796 0.204 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.795 0.205 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.793 0.207 0.000
B37.0 Candidal stomatitis
0.793 0.207 0.000
S56 Injury of muscle and tendon at forearm level
0.793 0.207 0.000
M31 Other necrotising vasculopathies
0.792 0.208 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.790 0.210 0.000
H43 Disorders of vitreous body
0.789 0.211 0.000
S20-S29 Injuries to the thorax
0.788 0.212 0.000
H53-H54 Visual disturbances and blindness
0.788 0.212 0.000
Y84.2 Radiological procedure and radiotherapy
0.786 0.214 0.000
B25-B34 Other viral diseases
0.785 0.215 0.000
W75-W84 Other accidental threats to breathing
0.784 0.216 0.000
T92 Sequelae of injuries of upper limb
0.784 0.216 0.000
S51 Open wound of forearm
0.782 0.218 0.000
M23 Internal derangement of knee
0.780 0.220 0.000
W00-W19 Falls
0.780 0.220 0.000
S69 Other and unspecified injuries of wrist and hand
0.779 0.221 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.779 0.221 0.000
Q00-Q07 Congenital malformations of the nervous system
0.777 0.223 0.000
J34.3 Hypertrophy of nasal turbinates
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.777 0.223 0.000
I34.1 Mitral (valve) prolapse
0.776 0.224 0.000
M25.5 Pain in joint
0.776 0.224 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.775 0.225 0.000
S80-S89 Injuries to the knee and lower leg
0.775 0.225 0.000
S64.4 Injury of digital nerve of other finger
0.773 0.227 0.000
T87 Complications peculiar to reattachment and amputation
0.773 0.227 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.772 0.228 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.771 0.229 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.771 0.229 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.770 0.230 0.000
A80-A89 Viral infections of the central nervous system
0.770 0.230 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.769 0.231 0.000
Y95 Nosocomial condition
0.767 0.233 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.767 0.233 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.767 0.233 0.000
Y84.6 Urinary catheterisation
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.766 0.234 0.000
M22.4 Chondromalacia patellae
0.765 0.235 0.000
Q21 Congenital malformations of cardiac septa
0.764 0.236 0.000
M80-M85 Disorders of bone density and structure
0.764 0.236 0.000
M94.8 Other specified disorders of cartilage
0.760 0.239 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.759 0.241 0.000
H30-H36 Disorders of choroid and retina
0.758 0.242 0.000
Q63 Other congenital malformations of kidney
0.755 0.245 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.755 0.245 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.755 0.245 0.000
H11.3 Conjunctival haemorrhage
0.754 0.246 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.754 0.246 0.000
I27.2 Other secondary pulmonary hypertension
0.754 0.246 0.000
I35.8 Other aortic valve disorders
0.753 0.247 0.000
J69 Pneumonitis due to solids and liquids
0.753 0.247 0.000
A40 Streptococcal septicaemia
0.753 0.247 0.000
Y48 Anaesthetics and therapeutic gases
0.752 0.248 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.751 0.248 0.000
Y84.4 Aspiration of fluid
0.751 0.249 0.000
I27.9 Pulmonary heart disease, unspecified
0.750 0.250 0.000
Y86 Sequelae of other accidents
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.747 0.253 0.000
G58 Other mononeuropathies
0.747 0.253 0.000
I33 Acute and subacute endocarditis
0.745 0.255 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.743 0.257 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.742 0.258 0.000
I44.2 Atrioventricular block, complete
0.740 0.260 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.739 0.261 0.000
S60.8 Other superficial injuries of wrist and hand
0.739 0.261 0.000
S30.1 Contusion of abdominal wall
0.739 0.261 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.738 0.262 0.000
G60 Hereditary and idiopathic neuropathy
0.738 0.262 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.737 0.262 0.000
I51 Complications and ill-defined descriptions of heart disease
0.737 0.263 0.000
J46 Status asthmaticus
0.737 0.263 0.000
T98 Sequelae of other and unspecified effects of external causes
0.736 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
J14 Pneumonia due to Haemophilus influenzae
0.735 0.265 0.000
M30 Polyarteritis nodosa and related conditions
0.735 0.265 0.000
T90.8 Sequelae of other specified injuries of head
0.734 0.266 0.000
G51.0 Bell's palsy
0.733 0.267 0.000
I71 Aortic aneurysm and dissection
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.729 0.271 0.000
T78 Adverse effects, not elsewhere classified
0.729 0.271 0.000
Y85 Sequelae of transport accidents
0.729 0.271 0.000
G30 Alzheimer's disease
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
H43.8 Other disorders of vitreous body
0.728 0.272 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.727 0.273 0.000
H25 Senile cataract
0.727 0.273 0.000
S52.0 Fracture of upper end of ulna
0.726 0.274 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.726 0.274 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.726 0.274 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.724 0.276 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.724 0.276 0.000
I30 Acute pericarditis
0.723 0.277 0.000
M94.2 Chondromalacia
0.723 0.277 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
M24.2 Disorder of ligament
0.721 0.279 0.000
B49 Unspecified mycosis
0.720 0.280 0.000
S62.6 Fracture of other finger
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I45 Other conduction disorders
0.715 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
S92 Fracture of foot, except ankle
0.715 0.285 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.715 0.285 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.714 0.286 0.000
Q35-Q37 Cleft lip and cleft palate
0.714 0.286 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.714 0.286 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.714 0.286 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.714 0.286 0.000
J45.8 Mixed asthma
0.714 0.286 0.000
J45.1 Nonallergic asthma
0.714 0.286 0.000
H21 Other disorders of iris and ciliary body
0.714 0.286 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
H54 Blindness and low vision
0.712 0.288 0.000
H18.5 Hereditary corneal dystrophies
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
I28 Other diseases of pulmonary vessels
0.712 0.288 0.000
A48 Other bacterial diseases, not elsewhere classified
0.711 0.289 0.000
A44 Bartonellosis
0.711 0.289 0.000
A43 Nocardiosis
0.711 0.289 0.000
A42 Actinomycosis
0.711 0.289 0.000
A39 Meningococcal infection
0.711 0.289 0.000
A37 Whooping cough
0.711 0.289 0.000
A36 Diphtheria
0.711 0.289 0.000
A32 Listeriosis
0.711 0.289 0.000
A31 Infection due to other mycobacteria
0.711 0.289 0.000
A30 Leprosy [Hansen's disease]
0.711 0.289 0.000
A46 Erysipelas
0.711 0.289 0.000
A38 Scarlet fever
0.711 0.289 0.000
A35 Other tetanus
0.711 0.289 0.000
A34 Obstetrical tetanus
0.711 0.289 0.000
A33 Tetanus neonatorum
0.711 0.289 0.000
H46 Optic neuritis
0.711 0.289 0.000
M34.8 Other forms of systemic sclerosis
0.711 0.289 0.000
J39 Other diseases of upper respiratory tract
0.710 0.290 0.000
J32 Chronic sinusitis
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.708 0.292 0.000
A41.4 Septicaemia due to anaerobes
0.706 0.294 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
S52.51 Fracture of lower end of radius (open)
0.704 0.295 0.000
Q27 Other congenital malformations of peripheral vascular system
0.704 0.296 0.000
Q85 Phakomatoses, not elsewhere classified
0.704 0.296 0.000
M34.9 Systemic sclerosis, unspecified
0.703 0.296 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.703 0.297 0.000
I44.5 Left posterior fascicular block
0.702 0.298 0.000
I44.4 Left anterior fascicular block
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.701 0.299 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.701 0.299 0.000
H10 Conjunctivitis
0.701 0.299 0.000
Q64 Other congenital malformations of urinary system
0.699 0.301 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.699 0.301 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.699 0.301 0.000
B65-B83 Helminthiases
0.699 0.301 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.699 0.301 0.000
S00-S09 Injuries to the head
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.697 0.303 0.000
M33 Dermatopolymyositis
0.697 0.303 0.000
M32 Systemic lupus erythematosus
0.697 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
H25.9 Senile cataract, unspecified
0.696 0.304 0.000
J00-J06 Acute upper respiratory infections
0.696 0.304 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.696 0.304 0.000
S67 Crushing injury of wrist and hand
0.695 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.695 0.304 0.000
S59 Other and unspecified injuries of forearm
0.695 0.305 0.000
S58 Traumatic amputation of forearm
0.695 0.305 0.000
S57 Crushing injury of forearm
0.695 0.305 0.000
S55 Injury of blood vessels at forearm level
0.695 0.305 0.000
S54 Injury of nerves at forearm level
0.695 0.305 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.695 0.305 0.000
M35.3 Polymyalgia rheumatica
0.694 0.306 0.000
M86-M90 Other osteopathies
0.694 0.306 0.000
T90.4 Sequelae of injury of eye and orbit
0.694 0.306 0.000
H27 Other disorders of lens
0.694 0.306 0.000
B37.3 Candidiasis of vulva and vagina
0.694 0.306 0.000
Y52 Agents primarily affecting the cardiovascular system
0.693 0.307 0.000
J37 Chronic laryngitis and laryngotracheitis
0.693 0.307 0.000
W29 Contact with other powered hand tools and household machinery
0.693 0.307 0.000
S65 Injury of blood vessels at wrist and hand level
0.692 0.308 0.000
M34.1 CR(E)ST syndrome
0.691 0.309 0.000
I49.3 Ventricular premature depolarisation
0.691 0.309 0.000
M94.9 Disorder of cartilage, unspecified
0.690 0.310 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.690 0.310 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.690 0.310 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.690 0.310 0.000
T82.3 Mechanical complication of other vascular grafts
0.690 0.310 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.690 0.310 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.689 0.311 0.000
Q23 Congenital malformations of aortic and mitral valves
0.689 0.311 0.000
S82 Fracture of lower leg, including ankle
0.689 0.311 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.689 0.311 0.000
J43 Emphysema
0.688 0.312 0.000
G54 Nerve root and plexus disorders
0.688 0.312 0.000
I35.1 Aortic (valve) insufficiency
0.688 0.312 0.000
Y84.9 Medical procedure, unspecified
0.688 0.312 0.000
Y84.7 Blood-sampling
0.688 0.312 0.000
Y84.5 Insertion of gastric or duodenal sound
0.688 0.312 0.000
Y84.3 Shock therapy
0.688 0.312 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.687 0.313 0.000
D74 Methaemoglobinaemia
0.687 0.313 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.687 0.313 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.687 0.313 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.687 0.313 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.686 0.314 0.000
Q61.9 Cystic kidney disease, unspecified
0.686 0.314 0.000
Q61.8 Other cystic kidney diseases
0.686 0.314 0.000
Q61.5 Medullary cystic kidney
0.686 0.314 0.000
Q61.4 Renal dysplasia
0.686 0.314 0.000
Q61.1 Polycystic kidney, infantile type
0.686 0.314 0.000
J17 Pneumonia in diseases classified elsewhere
0.685 0.314 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.685 0.314 0.000
J12 Viral pneumonia, not elsewhere classified
0.685 0.314 0.000
J09 Influenza due to certain identified influenza virus
0.685 0.314 0.000
J11 Influenza, virus not identified
0.683 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.683 0.317 0.000
Y43.9 Primarily systemic agent, unspecified
0.682 0.318 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.682 0.318 0.000
Y43.6 Enzymes, not elsewhere classified
0.682 0.318 0.000
Y43.5 Acidifying and alkalising agents
0.682 0.318 0.000
Y43.2 Antineoplastic natural products
0.682 0.318 0.000
Y43.1 Antineoplastic antimetabolites
0.682 0.318 0.000
Y43.0 Antiallergic and antiemetic drugs
0.682 0.318 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.682 0.318 0.000
I77 Other disorders of arteries and arterioles
0.682 0.318 0.000
G51.9 Disorder of facial nerve, unspecified
0.682 0.318 0.000
T95 Sequelae of burns, corrosions and frostbite
0.681 0.318 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.681 0.318 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.681 0.318 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.681 0.318 0.000
S63.6 Sprain and strain of finger(s)
0.681 0.319 0.000
D80-D89 Certain disorders involving the immune mechanism
0.680 0.320 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.679 0.320 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.679 0.321 0.000
G64 Other disorders of peripheral nervous system
0.679 0.321 0.000
I27.8 Other specified pulmonary heart diseases
0.678 0.322 0.000
G50 Disorders of trigeminal nerve
0.678 0.322 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.678 0.322 0.000
H35 Other retinal disorders
0.677 0.323 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.677 0.323 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.677 0.323 0.000
T68 Hypothermia
0.676 0.324 0.000
H66 Suppurative and unspecified otitis media
0.675 0.325 0.000
I36 Nonrheumatic tricuspid valve disorders
0.675 0.325 0.000
J69.0 Pneumonitis due to food and vomit
0.675 0.325 0.000
M25.3 Other instability of joint
0.674 0.326 0.000
H17 Corneal scars and opacities
0.672 0.327 0.000
I99 Other and unspecified disorders of circulatory system
0.672 0.328 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.672 0.328 0.000
T91 Sequelae of injuries of neck and trunk
0.671 0.329 0.000
B15-B19 Viral hepatitis
0.670 0.330 0.000
M25.59 Pain in joint (Site unspecified)
0.669 0.331 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.669 0.331 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.668 0.332 0.000
S36 Injury of intra-abdominal organs
0.667 0.333 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.667 0.333 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.667 0.333 0.000
Q21.1 Atrial septal defect
0.666 0.334 0.000
D55-D59 Haemolytic anaemias
0.666 0.334 0.000
J33.1 Polypoid sinus degeneration
0.666 0.334 0.000
T90.9 Sequelae of unspecified injury of head
0.666 0.334 0.000
I95.8 Other hypotension
0.665 0.335 0.000
I95.0 Idiopathic hypotension
0.665 0.335 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.665 0.335 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.665 0.335 0.000
H15 Disorders of sclera
0.665 0.335 0.000
Q89 Other congenital malformations, not elsewhere classified
0.665 0.335 0.000
J18.0 Bronchopneumonia, unspecified
0.664 0.336 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.664 0.336 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.662 0.338 0.000
S52.9 Fracture of forearm, part unspecified
0.662 0.338 0.000
S52.7 Multiple fractures of forearm
0.662 0.338 0.000
S52.4 Fracture of shafts of both ulna and radius
0.662 0.338 0.000
S52.3 Fracture of shaft of radius
0.662 0.338 0.000
S52.2 Fracture of shaft of ulna
0.662 0.338 0.000
M21.1 Varus deformity, not elsewhere classified
0.661 0.338 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.661 0.339 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.661 0.339 0.000
I44.6 Other and unspecified fascicular block
0.661 0.339 0.000
I27.0 Primary pulmonary hypertension
0.661 0.339 0.000
I44.7 Left bundle-branch block, unspecified
0.661 0.339 0.000
S50 Superficial injury of forearm
0.660 0.339 0.000
S90 Superficial injury of ankle and foot
0.660 0.340 0.000
A49.0 Staphylococcal infection, unspecified
0.660 0.340 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.660 0.340 0.000
H20.0 Acute and subacute iridocyclitis
0.659 0.341 0.000
M24.0 Loose body in joint
0.659 0.341 0.000
T86.0 Bone-marrow transplant rejection
0.659 0.341 0.000
D72 Other disorders of white blood cells
0.658 0.342 0.000
G62.2 Polyneuropathy due to other toxic agents
0.658 0.342 0.000
G62.1 Alcoholic polyneuropathy
0.658 0.342 0.000
G62.0 Drug-induced polyneuropathy
0.658 0.342 0.000
S52.6 Fracture of lower end of both ulna and radius
0.658 0.342 0.000
Y83.4 Other reconstructive surgery
0.657 0.343 0.000
G90-G99 Other disorders of the nervous system
0.657 0.343 0.000
Y84.1 Kidney dialysis
0.657 0.343 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.657 0.343 0.000
Q28 Other congenital malformations of circulatory system
0.655 0.344 0.000
J22 Unspecified acute lower respiratory infection
0.655 0.345 0.000
B48 Other mycoses, not elsewhere classified
0.654 0.346 0.000
B47 Mycetoma
0.654 0.346 0.000
B46 Zygomycosis
0.654 0.346 0.000
B45 Cryptococcosis
0.654 0.346 0.000
B43 Chromomycosis and phaeomycotic abscess
0.654 0.346 0.000
B42 Sporotrichosis
0.654 0.346 0.000
B41 Paracoccidioidomycosis
0.654 0.346 0.000
B40 Blastomycosis
0.654 0.346 0.000
B39 Histoplasmosis
0.654 0.346 0.000
B38 Coccidioidomycosis
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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