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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78714084
log Bayes Factor = 18.8347
Chromosome 8   position 89,031,066  (GRCh37) Explore rs78714084 on Ensembl!
Variant rs78714084 is part of Cluster X0201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
N17-N19 Renal failure
0.995 0.005 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.995 0.005 0.000
N60-N64 Disorders of breast
0.994 0.006 0.000
I50 Heart failure
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.986 0.014 0.000
I34 Nonrheumatic mitral valve disorders
0.985 0.015 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.980 0.020 0.000
I50.9 Heart failure, unspecified
0.977 0.023 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.976 0.024 0.000
I34.0 Mitral (valve) insufficiency
0.975 0.025 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.974 0.026 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.972 0.028 0.000
M54 Dorsalgia
0.970 0.030 0.000
M54.5 Low back pain
0.966 0.034 0.000
N60 Benign mammary dysplasia
0.964 0.036 0.000
M54.59 Low back pain (Site unspecified)
0.963 0.037 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.962 0.038 0.000
N18 Chronic renal failure
0.961 0.039 0.000
N64 Other disorders of breast
0.959 0.041 0.000
C34 Malignant neoplasm of bronchus and lung
0.952 0.048 0.000
I73 Other peripheral vascular diseases
0.950 0.050 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.945 0.055 0.000
A00-A09 Intestinal infectious diseases
0.945 0.055 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.945 0.055 0.000
N18.3 Chronic kidney disease, stage 3
0.942 0.058 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.942 0.058 0.000
I50.0 Congestive heart failure
0.942 0.058 0.000
N19 Unspecified renal failure
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.935 0.065 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.934 0.066 0.000
Chapter XXII Codes for special purposes
0.929 0.071 0.000
I73.9 Peripheral vascular disease, unspecified
0.929 0.071 0.000
I74 Arterial embolism and thrombosis
0.928 0.072 0.000
N25-N29 Other disorders of kidney and ureter
0.919 0.081 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.917 0.083 0.000
C78.0 Secondary malignant neoplasm of lung
0.915 0.085 0.000
N60.8 Other benign mammary dysplasias
0.914 0.086 0.000
C34.9 Bronchus or lung, unspecified
0.911 0.089 0.000
E10-E14 Diabetes mellitus
0.910 0.090 0.000
F60-F69 Disorders of adult personality and behaviour
0.909 0.091 0.000
C78.7 Secondary malignant neoplasm of liver
0.907 0.093 0.000
C77.2 Intra-abdominal lymph nodes
0.907 0.093 0.000
E50-E64 Other nutritional deficiencies
0.907 0.093 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.907 0.093 0.000
M05-M14 Inflammatory polyarthropathies
0.904 0.096 0.000
T39.1 4-Aminophenol derivatives
0.904 0.096 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.901 0.099 0.000
T39.0 Salicylates
0.901 0.099 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.899 0.101 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.899 0.101 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.898 0.102 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.897 0.103 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.893 0.107 0.000
I71 Aortic aneurysm and dissection
0.889 0.111 0.000
I72 Other aneurysm
0.889 0.111 0.000
C77.5 Intrapelvic lymph nodes
0.887 0.113 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.886 0.114 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.885 0.115 0.000
C34.1 Upper lobe, bronchus or lung
0.885 0.115 0.000
N63 Unspecified lump in breast
0.880 0.120 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.877 0.123 0.000
N64.8 Other specified disorders of breast
0.877 0.123 0.000
N17 Acute renal failure
0.876 0.124 0.000
T66-T78 Other and unspecified effects of external causes
0.874 0.126 0.000
M06 Other rheumatoid arthritis
0.874 0.126 0.000
Y43 Primarily systemic agents
0.874 0.126 0.000
M51 Other intervertebral disk disorders
0.873 0.127 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.871 0.129 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.868 0.132 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.865 0.135 0.000
A30-A49 Other bacterial diseases
0.865 0.135 0.000
N60.0 Solitary cyst of breast
0.863 0.137 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.862 0.137 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.862 0.138 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.862 0.138 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.861 0.139 0.000
X60-X84 Intentional self-harm
0.860 0.140 0.000
C64-C68 Malignant neoplasms of urinary tract
0.856 0.144 0.000
M06.9 Rheumatoid arthritis, unspecified
0.853 0.147 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.851 0.149 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.849 0.150 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.849 0.151 0.000
I77 Other disorders of arteries and arterioles
0.840 0.160 0.000
C77.1 Intrathoracic lymph nodes
0.835 0.165 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.835 0.165 0.000
M70-M79 Other soft tissue disorders
0.833 0.167 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.828 0.172 0.000
T40.2 Other opioids
0.828 0.172 0.000
N64.4 Mastodynia
0.827 0.173 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.826 0.174 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.825 0.175 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.825 0.175 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.824 0.176 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.824 0.176 0.000
N00-N08 Glomerular diseases
0.821 0.179 0.000
I69 Sequelae of cerebrovascular disease
0.819 0.181 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.813 0.187 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.812 0.188 0.000
I72.4 Aneurysm of artery of lower extremity
0.811 0.189 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.811 0.189 0.000
E53 Deficiency of other B group vitamins
0.810 0.190 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.810 0.190 0.000
C77.0 Lymph nodes of head, face and neck
0.810 0.190 0.000
S60-S69 Injuries to the wrist and hand
0.809 0.191 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.809 0.191 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.808 0.192 0.000
F03 Unspecified dementia
0.806 0.194 0.000
C79.6 Secondary malignant neoplasm of ovary
0.806 0.194 0.000
Y43.3 Other antineoplastic drugs
0.803 0.197 0.000
E11 Non-insulin-dependent diabetes mellitus
0.803 0.197 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.802 0.198 0.000
C78.2 Secondary malignant neoplasm of pleura
0.802 0.198 0.000
E10 Insulin-dependent diabetes mellitus
0.802 0.198 0.000
F60 Specific personality disorders
0.801 0.199 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.801 0.199 0.000
B35-B49 Mycoses
0.801 0.199 0.000
W20-W49 Exposure to inanimate mechanical forces
0.800 0.199 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.799 0.201 0.000
I67 Other cerebrovascular diseases
0.798 0.202 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.797 0.203 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.795 0.205 0.000
S20-S29 Injuries to the thorax
0.794 0.206 0.000
Y57 Other and unspecified drugs and medicaments
0.792 0.207 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.788 0.212 0.000
F20 Schizophrenia
0.787 0.213 0.000
M75 Shoulder lesions
0.786 0.214 0.000
A08 Viral and other specified intestinal infections
0.785 0.215 0.000
C80 Malignant neoplasm without specification of site
0.784 0.216 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.784 0.216 0.000
N18.4 Chronic kidney disease, stage 4
0.784 0.216 0.000
M75.0 Adhesive capsulitis of shoulder
0.784 0.216 0.000
I50.1 Left ventricular failure
0.783 0.217 0.000
I34.1 Mitral (valve) prolapse
0.779 0.221 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
C01 Malignant neoplasm of base of tongue
0.777 0.223 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.777 0.223 0.000
M54.56 Low back pain (Lumbar region)
0.777 0.223 0.000
T82.3 Mechanical complication of other vascular grafts
0.775 0.225 0.000
S10-S19 Injuries to the neck
0.774 0.226 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.774 0.226 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.773 0.227 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.228 0.000
S80-S89 Injuries to the knee and lower leg
0.769 0.230 0.000
A41 Other septicaemia
0.769 0.231 0.000
I37 Pulmonary valve disorders
0.769 0.231 0.000
I60 Subarachnoid haemorrhage
0.768 0.232 0.000
F41 Other anxiety disorders
0.767 0.233 0.000
E65-E68 Obesity and other hyperalimentation
0.766 0.234 0.000
E40-E46 Malnutrition
0.765 0.235 0.000
M80-M85 Disorders of bone density and structure
0.764 0.236 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.763 0.237 0.000
T78 Adverse effects, not elsewhere classified
0.762 0.238 0.000
N28.0 Ischaemia and infarction of kidney
0.758 0.242 0.000
Y52 Agents primarily affecting the cardiovascular system
0.757 0.243 0.000
F69 Unspecified disorder of adult personality and behaviour
0.757 0.243 0.000
Chapter VI Diseases of the nervous system
0.757 0.243 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
N17.9 Acute renal failure, unspecified
0.756 0.244 0.000
V10-V19 Pedal cyclist injured in transport accident
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.754 0.246 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.754 0.246 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.754 0.246 0.000
I38 Endocarditis, valve unspecified
0.753 0.247 0.000
N64.1 Fat necrosis of breast
0.751 0.249 0.000
C91 Lymphoid leukaemia
0.750 0.250 0.000
I33 Acute and subacute endocarditis
0.749 0.251 0.000
F80-F89 Disorders of psychological development
0.748 0.252 0.000
E20-E35 Disorders of other endocrine glands
0.747 0.252 0.000
N99-N99 Other disorders of the genitourinary system
0.746 0.254 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.746 0.254 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.746 0.254 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
E55 Vitamin D deficiency
0.743 0.257 0.000
Y40 Systemic antibiotics
0.742 0.258 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.741 0.259 0.000
C10 Malignant neoplasm of oropharynx
0.739 0.261 0.000
E70-E90 Metabolic disorders
0.739 0.261 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.738 0.262 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.736 0.264 0.000
F10.1 Harmful use
0.736 0.264 0.000
E10.9 Without complications
0.735 0.265 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.265 0.000
N64.5 Other signs and symptoms in breast
0.735 0.265 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.734 0.266 0.000
I31 Other diseases of pericardium
0.731 0.269 0.000
M65-M68 Disorders of synovium and tendon
0.730 0.269 0.000
I30 Acute pericarditis
0.730 0.270 0.000
I46 Cardiac arrest
0.729 0.271 0.000
F99-F99 Unspecified mental disorder
0.729 0.271 0.000
N18.0 End-stage renal disease
0.729 0.271 0.000
I77.1 Stricture of artery
0.727 0.273 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.725 0.275 0.000
E11.2 With renal complications
0.725 0.275 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.723 0.277 0.000
S00-S09 Injuries to the head
0.723 0.277 0.000
F05.9 Delirium, unspecified
0.723 0.277 0.000
I65.2 Occlusion and stenosis of carotid artery
0.722 0.278 0.000
I36 Nonrheumatic tricuspid valve disorders
0.721 0.279 0.000
M91-M94 Chondropathies
0.721 0.279 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.720 0.280 0.000
A41.9 Septicaemia, unspecified
0.720 0.280 0.000
F10.2 Dependence syndrome
0.720 0.280 0.000
I67.9 Cerebrovascular disease, unspecified
0.719 0.281 0.000
U80 Agent resistant to penicillin and related antibiotics
0.718 0.282 0.000
C79.2 Secondary malignant neoplasm of skin
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.717 0.283 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.716 0.284 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.716 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.715 0.284 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.715 0.284 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.715 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.715 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.714 0.286 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.714 0.286 0.000
F41.2 Mixed anxiety and depressive disorder
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
N60.1 Diffuse cystic mastopathy
0.712 0.288 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.711 0.288 0.000
W44 Foreign body entering into or through eye or natural orifice
0.711 0.289 0.000
I70 Atherosclerosis
0.711 0.289 0.000
C50-C50 Malignant neoplasm of breast
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
I62 Other nontraumatic intracranial haemorrhage
0.709 0.291 0.000
M54.2 Cervicalgia
0.709 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
G90-G99 Other disorders of the nervous system
0.707 0.293 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.707 0.293 0.000
T39.4 Antirheumatics, not elsewhere classified
0.707 0.293 0.000
T39.2 Pyrazolone derivatives
0.707 0.293 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.707 0.293 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.706 0.294 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.706 0.294 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.706 0.294 0.000
M07 Psoriatic and enteropathic arthropathies
0.706 0.294 0.000
C67 Malignant neoplasm of bladder
0.706 0.294 0.000
N60.4 Mammary duct ectasia
0.706 0.294 0.000
S40-S49 Injuries to the shoulder and upper arm
0.705 0.295 0.000
D50-D53 Nutritional anaemias
0.704 0.296 0.000
S64 Injury of nerves at wrist and hand level
0.704 0.296 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.702 0.298 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.701 0.299 0.000
N60.3 Fibrosclerosis of breast
0.701 0.299 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.700 0.300 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.700 0.300 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.700 0.300 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.700 0.300 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.700 0.300 0.000
N17.0 Acute renal failure with tubular necrosis
0.700 0.300 0.000
D60-D64 Aplastic and other anaemias
0.699 0.301 0.000
N28.8 Other specified disorders of kidney and ureter
0.699 0.301 0.000
C77.8 Lymph nodes of multiple regions
0.698 0.302 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.698 0.302 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.698 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.302 0.000
Y10-Y34 Event of undetermined intent
0.698 0.302 0.000
Y00-Y09 Assault
0.698 0.302 0.000
X85-X99 Assault
0.698 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.302 0.000
X50-X57 Overexertion, travel and privation
0.698 0.302 0.000
X30-X39 Exposure to forces of nature
0.698 0.302 0.000
X10-X19 Contact with heat and hot substances
0.698 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.698 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.302 0.000
W75-W84 Other accidental threats to breathing
0.698 0.302 0.000
W65-W74 Accidental drowning and submersion
0.698 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.698 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.698 0.302 0.000
V95-V97 Air and space transport accidents
0.698 0.302 0.000
V90-V94 Water transport accidents
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
F20.0 Paranoid schizophrenia
0.697 0.303 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.697 0.303 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.697 0.303 0.000
C32 Malignant neoplasm of larynx
0.697 0.303 0.000
C31 Malignant neoplasm of accessory sinuses
0.697 0.303 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.697 0.303 0.000
C37 Malignant neoplasm of thymus
0.697 0.303 0.000
C33 Malignant neoplasm of trachea
0.697 0.303 0.000
I05-I09 Chronic rheumatic heart diseases
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.695 0.304 0.000
E53.8 Deficiency of other specified B group vitamins
0.695 0.305 0.000
M54.8 Other dorsalgia
0.695 0.305 0.000
M54.6 Pain in thoracic spine
0.695 0.305 0.000
M54.0 Panniculitis affecting regions of neck and back
0.695 0.305 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.693 0.307 0.000
M54.55 Low back pain (Thoracolumbar region)
0.693 0.307 0.000
M54.54 Low back pain-Thoracic
0.693 0.307 0.000
M54.53 Low back pain-Cervicothoracic
0.693 0.307 0.000
M54.52 Low back pain-Cervical
0.693 0.307 0.000
M54.51 Low back pain-Occipit-atl-axl
0.693 0.307 0.000
M54.50 Low back pain (Multiple sites in spine)
0.693 0.307 0.000
N60.9 Benign mammary dysplasia, unspecified
0.691 0.308 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.690 0.310 0.000
N61 Inflammatory disorders of breast
0.690 0.310 0.000
C77.4 Inguinal and lower limb lymph nodes
0.690 0.310 0.000
N18.8 Other chronic renal failure
0.689 0.311 0.000
N18.2 Chronic kidney disease, stage 2
0.689 0.311 0.000
N18.1 Chronic kidney disease, stage 1
0.689 0.311 0.000
D80-D89 Certain disorders involving the immune mechanism
0.689 0.311 0.000
T17 Foreign body in respiratory tract
0.688 0.311 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.688 0.312 0.000
E61 Deficiency of other nutrient elements
0.688 0.312 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.688 0.312 0.000
N64.3 Galactorrhoea not associated with childbirth
0.687 0.312 0.000
N64.2 Atrophy of breast
0.687 0.312 0.000
N64.0 Fissure and fistula of nipple
0.687 0.312 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.687 0.313 0.000
M51.9 Intervertebral disk disorder, unspecified
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.686 0.313 0.000
N64.9 Disorder of breast, unspecified
0.686 0.314 0.000
E16 Other disorders of pancreatic internal secretion
0.685 0.314 0.000
F30-F39 Mood [affective] disorders
0.685 0.315 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.685 0.315 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.684 0.316 0.000
Y57.9 Drug or medicament, unspecified
0.683 0.316 0.000
C34.8 Overlapping lesion of bronchus and lung
0.682 0.317 0.000
C34.2 Middle lobe, bronchus or lung
0.682 0.317 0.000
C34.0 Main bronchus
0.682 0.317 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.682 0.318 0.000
I73.8 Other specified peripheral vascular diseases
0.681 0.319 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.681 0.319 0.000
U88 Agent resistant to multiple antibiotics
0.681 0.319 0.000
F60.3 Emotionally unstable personality disorder
0.680 0.320 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
T86 Failure and rejection of transplanted organs and tissues
0.678 0.322 0.000
A07 Other protozoal intestinal diseases
0.678 0.322 0.000
A06 Amoebiasis
0.678 0.322 0.000
A05 Other bacterial foodborne intoxications
0.678 0.322 0.000
A03 Shigellosis
0.678 0.322 0.000
A02 Other Salmonella infections
0.678 0.322 0.000
A01 Typhoid and paratyphoid fevers
0.678 0.322 0.000
A00 Cholera
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.323 0.000
Y58 Bacterial vaccines
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.323 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.323 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.323 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.323 0.000
T88.4 Failed or difficult intubation
0.677 0.323 0.000
E11.4 With neurological complications
0.676 0.324 0.000
M54.4 Lumbago with sciatica
0.676 0.324 0.000
F05.8 Other delirium
0.676 0.324 0.000
T68 Hypothermia
0.675 0.325 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.674 0.326 0.000
I74.5 Embolism and thrombosis of iliac artery
0.674 0.326 0.000
Y43.1 Antineoplastic antimetabolites
0.673 0.327 0.000
U51 Admission status on psychiatric patients
0.672 0.328 0.000
E53.9 Vitamin B deficiency, unspecified
0.671 0.329 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
T23 Burn and corrosion of wrist and hand
0.670 0.330 0.000
C91.1 Chronic lymphocytic leukaemia
0.670 0.330 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.670 0.330 0.000
A08.4 Viral intestinal infection, unspecified
0.669 0.331 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.668 0.332 0.000
S27 Injury of other and unspecified intrathoracic organs
0.667 0.333 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.666 0.333 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.666 0.334 0.000
I74.8 Embolism and thrombosis of other arteries
0.666 0.334 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.666 0.334 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.666 0.334 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.666 0.334 0.000
D55-D59 Haemolytic anaemias
0.666 0.334 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.665 0.334 0.000
E27 Other disorders of adrenal gland
0.664 0.336 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.663 0.337 0.000
T45.0 Antiallergic and antiemetic drugs
0.661 0.339 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.661 0.339 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.660 0.340 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.659 0.341 0.000
N27 Small kidney of unknown cause
0.659 0.341 0.000
N25 Disorders resulting from impaired renal tubular function
0.659 0.341 0.000
N26 Unspecified contracted kidney
0.659 0.341 0.000
N20-N23 Urolithiasis
0.659 0.341 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.658 0.342 0.000
F60.9 Personality disorder, unspecified
0.658 0.342 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.657 0.343 0.000
F02 Dementia in other diseases classified elsewhere
0.657 0.343 0.000
F09 Unspecified organic or symptomatic mental disorder
0.657 0.343 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.657 0.343 0.000
S79 Other and unspecified injuries of hip and thigh
0.656 0.344 0.000
X62.9 Unspecified place
0.655 0.345 0.000
T78.2 Anaphylactic shock, unspecified
0.655 0.345 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
M51.8 Other specified intervertebral disk disorders
0.655 0.345 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.654 0.346 0.000
I69.3 Sequelae of cerebral infarction
0.654 0.346 0.000
C09 Malignant neoplasm of tonsil
0.653 0.346 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.653 0.347 0.000
E12 Malnutrition-related diabetes mellitus
0.653 0.347 0.000
E13 Other specified diabetes mellitus
0.652 0.348 0.000
Y43.4 Immunosuppressive agents
0.652 0.348 0.000
F68 Other disorders of adult personality and behaviour
0.652 0.348 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.652 0.348 0.000
F65 Disorders of sexual preference
0.652 0.348 0.000
F64 Gender identity disorders
0.652 0.348 0.000
F63 Habit and impulse disorders
0.652 0.348 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.652 0.348 0.000
F61 Mixed and other personality disorders
0.652 0.348 0.000
M85 Other disorders of bone density and structure
0.651 0.348 0.000
F43 Reaction to severe stress, and adjustment disorders
0.651 0.349 0.000
A04 Other bacterial intestinal infections
0.650 0.349 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.650 0.350 0.000
E63 Other nutritional deficiencies
0.650 0.350 0.000
E56 Other vitamin deficiencies
0.650 0.350 0.000
E51 Thiamine deficiency
0.650 0.350 0.000
E50 Vitamin A deficiency
0.650 0.350 0.000
E60 Dietary zinc deficiency
0.650 0.350 0.000
E59 Dietary selenium deficiency
0.650 0.350 0.000
E58 Dietary calcium deficiency
0.650 0.350 0.000
E54 Ascorbic acid deficiency
0.650 0.350 0.000
E52 Niacin deficiency [pellagra]
0.650 0.350 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.648 0.351 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.648 0.352 0.000
M14 Arthropathies in other diseases classified elsewhere
0.648 0.352 0.000
M12 Other specific arthropathies
0.648 0.352 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.648 0.352 0.000
M08 Juvenile arthritis
0.648 0.352 0.000
C66 Malignant neoplasm of ureter
0.648 0.352 0.000
M05 Seropositive rheumatoid arthritis
0.647 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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