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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7871607
log Bayes Factor = 24.204
Chromosome 9   position 85,546,352  (GRCh37) Explore rs7871607 on Ensembl!
Variant rs7871607 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
I25.1 Atherosclerotic heart disease
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
O60-O75 Complications of labour and delivery
0.995 0.005 0.000
R63 Symptoms and signs concerning food and fluid intake
0.990 0.010 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.990 0.010 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.990 0.010 0.000
I10-I15 Hypertensive diseases
0.988 0.012 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.985 0.015 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.984 0.016 0.000
Y83.8 Other surgical procedures
0.982 0.018 0.000
M15-M19 Arthrosis
0.981 0.019 0.000
I10 Essential (primary) hypertension
0.981 0.019 0.000
Chapter II Neoplasms
0.980 0.020 0.000
R63.4 Abnormal weight loss
0.979 0.021 0.000
M17 Gonarthrosis [arthrosis of knee]
0.975 0.025 0.000
R30-R39 Symptoms and signs involving the urinary system
0.974 0.026 0.000
I20 Angina pectoris
0.970 0.030 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.969 0.031 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.961 0.039 0.000
Chapter X Diseases of the respiratory system
0.959 0.041 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.958 0.042 0.000
R33 Retention of urine
0.956 0.044 0.000
Chapter VII Diseases of the eye and adnexa
0.955 0.045 0.000
M17.1 Other primary gonarthrosis
0.954 0.046 0.000
I21 Acute myocardial infarction
0.952 0.048 0.000
R53 Malaise and fatigue
0.952 0.048 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.948 0.052 0.000
Chapter XIV Diseases of the genitourinary system
0.948 0.052 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.941 0.059 0.000
O70 Perineal laceration during delivery
0.938 0.062 0.000
M25 Other joint disorders, not elsewhere classified
0.937 0.063 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.934 0.066 0.000
Z92 Personal history of medical treatment
0.931 0.069 0.000
M17.9 Gonarthrosis, unspecified
0.928 0.072 0.000
N30-N39 Other diseases of urinary system
0.927 0.073 0.000
R51 Headache
0.925 0.075 0.000
I21.9 Acute myocardial infarction, unspecified
0.923 0.077 0.000
Z86 Personal history of certain other diseases
0.921 0.079 0.000
J40-J47 Chronic lower respiratory diseases
0.914 0.086 0.000
O63 Long labour
0.914 0.086 0.000
R69 Unknown and unspecified causes of morbidity
0.912 0.088 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.908 0.092 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.907 0.093 0.000
M23 Internal derangement of knee
0.904 0.096 0.000
M25.7 Osteophyte
0.904 0.096 0.000
I24 Other acute ischaemic heart diseases
0.903 0.097 0.000
J09-J18 Influenza and pneumonia
0.902 0.098 0.000
J44 Other chronic obstructive pulmonary disease
0.901 0.099 0.000
Z95.1 Presence of aortocoronary bypass graft
0.899 0.101 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.898 0.102 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.895 0.105 0.000
I20.9 Angina pectoris, unspecified
0.893 0.107 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.891 0.109 0.000
R32 Unspecified urinary incontinence
0.890 0.110 0.000
I71 Aortic aneurysm and dissection
0.889 0.111 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.888 0.112 0.000
Z87 Personal history of other diseases and conditions
0.887 0.113 0.000
I25.2 Old myocardial infarction
0.885 0.115 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.885 0.115 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.884 0.116 0.000
O70.1 Second degree perineal laceration during delivery
0.884 0.116 0.000
N30 Cystitis
0.883 0.117 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.883 0.117 0.000
I30-I52 Other forms of heart disease
0.881 0.119 0.000
M70-M79 Other soft tissue disorders
0.878 0.122 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.875 0.125 0.000
Z85 Personal history of malignant neoplasm
0.873 0.127 0.000
N32 Other disorders of bladder
0.869 0.131 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.866 0.134 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.866 0.134 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.862 0.138 0.000
H30-H36 Disorders of choroid and retina
0.859 0.141 0.000
R61 Hyperhidrosis
0.857 0.143 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.853 0.147 0.000
R60 Oedema, not elsewhere classified
0.852 0.148 0.000
I20.0 Unstable angina
0.847 0.153 0.000
I65.2 Occlusion and stenosis of carotid artery
0.847 0.153 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.845 0.155 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.845 0.155 0.000
Z72 Problems related to lifestyle
0.843 0.157 0.000
O63.1 Prolonged second stage (of labour)
0.841 0.159 0.000
I51 Complications and ill-defined descriptions of heart disease
0.840 0.160 0.000
C15-C26 Malignant neoplasms of digestive organs
0.839 0.161 0.000
Z82.3 Family history of stroke
0.838 0.162 0.000
H53-H54 Visual disturbances and blindness
0.837 0.163 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.837 0.163 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.834 0.166 0.000
N30.9 Cystitis, unspecified
0.832 0.168 0.000
X60-X84 Intentional self-harm
0.832 0.168 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.831 0.169 0.000
J18 Pneumonia, organism unspecified
0.829 0.171 0.000
Z92.3 Personal history of irradiation
0.829 0.171 0.000
Z72.1 Alcohol use
0.828 0.172 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.825 0.175 0.000
Z80 Family history of malignant neoplasm
0.824 0.176 0.000
J90-J94 Other diseases of pleura
0.822 0.178 0.000
M05-M14 Inflammatory polyarthropathies
0.822 0.178 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.820 0.180 0.000
C64-C68 Malignant neoplasms of urinary tract
0.820 0.180 0.000
R63.0 Anorexia
0.813 0.187 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.812 0.188 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.812 0.188 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.811 0.189 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.810 0.190 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.810 0.190 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.809 0.191 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.809 0.191 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.809 0.191 0.000
Chapter VIII Diseases of the ear and mastoid process
0.806 0.194 0.000
R55 Syncope and collapse
0.806 0.194 0.000
O71 Other obstetric trauma
0.803 0.197 0.000
N20-N23 Urolithiasis
0.803 0.197 0.000
N32.8 Other specified disorders of bladder
0.802 0.198 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.202 0.000
M25.77 Osteophyte (Ankle and foot)
0.798 0.202 0.000
I51.8 Other ill-defined heart diseases
0.797 0.203 0.000
J18.1 Lobar pneumonia, unspecified
0.796 0.204 0.000
M31 Other necrotising vasculopathies
0.794 0.206 0.000
I22 Subsequent myocardial infarction
0.794 0.206 0.000
Z89 Acquired absence of limb
0.793 0.207 0.000
Z13 Special screening examination for other diseases and disorders
0.790 0.210 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.789 0.211 0.000
M79.6 Pain in limb
0.786 0.214 0.000
Z35 Supervision of high-risk pregnancy
0.785 0.215 0.000
D46 Myelodysplastic syndromes
0.782 0.218 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.779 0.221 0.000
I63 Cerebral infarction
0.778 0.222 0.000
M19 Other arthrosis
0.778 0.222 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.775 0.225 0.000
H25-H28 Disorders of lens
0.773 0.227 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.773 0.227 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.772 0.228 0.000
H33 Retinal detachments and breaks
0.772 0.228 0.000
H43-H45 Disorders of vitreous body and globe
0.772 0.228 0.000
R54 Senility
0.772 0.228 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.771 0.229 0.000
Chapter VI Diseases of the nervous system
0.770 0.230 0.000
Z99.1 Dependence on respirator
0.770 0.230 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.769 0.231 0.000
N39 Other disorders of urinary system
0.769 0.231 0.000
M35 Other systemic involvement of connective tissue
0.769 0.231 0.000
Z86.0 Personal history of other neoplasms
0.768 0.232 0.000
M24 Other specific joint derangements
0.768 0.232 0.000
I20.8 Other forms of angina pectoris
0.767 0.233 0.000
I24.8 Other forms of acute ischaemic heart disease
0.766 0.234 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.764 0.236 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.762 0.238 0.000
C80 Malignant neoplasm without specification of site
0.762 0.238 0.000
D41.4 Bladder
0.762 0.238 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.761 0.239 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.760 0.240 0.000
Y83.4 Other reconstructive surgery
0.760 0.240 0.000
Z86.4 Personal history of psychoactive substance abuse
0.759 0.241 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.759 0.241 0.000
R31 Unspecified haematuria
0.758 0.242 0.000
R50 Fever of unknown origin
0.758 0.242 0.000
J14 Pneumonia due to Haemophilus influenzae
0.757 0.243 0.000
Z98 Other postsurgical states
0.756 0.244 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.756 0.244 0.000
C78.0 Secondary malignant neoplasm of lung
0.756 0.244 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.755 0.245 0.000
R61.9 Hyperhidrosis, unspecified
0.754 0.246 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.754 0.246 0.000
R60.0 Localised oedema
0.752 0.248 0.000
R42 Dizziness and giddiness
0.749 0.251 0.000
O66 Other obstructed labour
0.747 0.253 0.000
M79.66 Pain in limb (Lower leg)
0.747 0.253 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.744 0.256 0.000
Z36 Antenatal screening
0.744 0.256 0.000
R68 Other general symptoms and signs
0.744 0.256 0.000
M25.76 Osteophyte (Lower leg)
0.743 0.257 0.000
M65-M68 Disorders of synovium and tendon
0.742 0.258 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.741 0.259 0.000
R30 Pain associated with micturition
0.740 0.259 0.000
O70.0 First degree perineal laceration during delivery
0.740 0.260 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.740 0.260 0.000
C25 Malignant neoplasm of pancreas
0.739 0.261 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.737 0.263 0.000
I77 Other disorders of arteries and arterioles
0.735 0.265 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.735 0.265 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.735 0.265 0.000
R87 Abnormal findings in specimens from female genital organs
0.734 0.266 0.000
D45 Polycythaemia vera
0.734 0.266 0.000
Chapter I Certain infectious and parasitic diseases
0.734 0.266 0.000
Z37 Outcome of delivery
0.734 0.266 0.000
I20.1 Angina pectoris with documented spasm
0.732 0.268 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.732 0.268 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.731 0.269 0.000
W20-W49 Exposure to inanimate mechanical forces
0.731 0.269 0.000
C78.7 Secondary malignant neoplasm of liver
0.729 0.271 0.000
J90 Pleural effusion, not elsewhere classified
0.729 0.271 0.000
I72 Other aneurysm
0.729 0.271 0.000
S50-S59 Injuries to the elbow and forearm
0.728 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
H53 Visual disturbances
0.728 0.272 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.728 0.272 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.727 0.273 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.727 0.273 0.000
M79.8 Other specified soft tissue disorders
0.725 0.275 0.000
Z13.9 Special screening examination, unspecified
0.725 0.275 0.000
Z34 Supervision of normal pregnancy
0.725 0.275 0.000
T81 Complications of procedures, not elsewhere classified
0.725 0.275 0.000
M25.74 Osteophyte (Hand)
0.724 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
V10-V19 Pedal cyclist injured in transport accident
0.722 0.277 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.721 0.279 0.000
Y83.9 Surgical procedure, unspecified
0.721 0.279 0.000
H35 Other retinal disorders
0.720 0.280 0.000
H55-H59 Other disorders of eye and adnexa
0.719 0.281 0.000
Z92.0 Personal history of contraception
0.719 0.281 0.000
I51.9 Heart disease, unspecified
0.719 0.281 0.000
Z94 Transplanted organ and tissue status
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z97 Presence of other devices
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R57 Shock, not elsewhere classified
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.715 0.285 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.714 0.286 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.714 0.286 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.713 0.287 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O73 Retained placenta and membranes, without haemorrhage
0.713 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O62 Abnormalities of forces of labour
0.713 0.287 0.000
O61 Failed induction of labour
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
W00-W19 Falls
0.713 0.287 0.000
R40 Somnolence, stupor and coma
0.712 0.288 0.000
Z03.4 Observation for suspected myocardial infarction
0.712 0.288 0.000
M86-M90 Other osteopathies
0.711 0.289 0.000
N10-N16 Renal tubulo-interstitial diseases
0.710 0.290 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.710 0.290 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.710 0.290 0.000
R63.5 Abnormal weight gain
0.710 0.290 0.000
R63.3 Feeding difficulties and mismanagement
0.710 0.290 0.000
R63.2 Polyphagia
0.710 0.290 0.000
R63.1 Polydipsia
0.710 0.290 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.709 0.290 0.000
Z95.3 Presence of xenogenic heart valve
0.709 0.290 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.709 0.291 0.000
I15 Secondary hypertension
0.708 0.291 0.000
I13 Hypertensive heart and renal disease
0.708 0.291 0.000
I11 Hypertensive heart disease
0.708 0.291 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.708 0.291 0.000
O63.0 Prolonged first stage (of labour)
0.708 0.292 0.000
O47 False labour
0.707 0.293 0.000
I73 Other peripheral vascular diseases
0.706 0.294 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.706 0.294 0.000
Y83.5 Amputation of limb(s)
0.706 0.294 0.000
Y83.3 Surgical operation with formation of external stoma
0.706 0.294 0.000
Y83.0 Surgical operation with transplant of whole organ
0.706 0.294 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M34 Systemic sclerosis
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.705 0.295 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.705 0.295 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.705 0.295 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.705 0.295 0.000
Z82.2 Family history of deafness and hearing loss
0.705 0.295 0.000
Z82.1 Family history of blindness and visual loss
0.705 0.295 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.705 0.295 0.000
M22 Disorders of patella
0.705 0.295 0.000
M40-M43 Deforming dorsopathies
0.704 0.296 0.000
M15 Polyarthrosis
0.704 0.296 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.297 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.702 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.297 0.000
N25-N29 Other disorders of kidney and ureter
0.702 0.298 0.000
M25.4 Effusion of joint
0.702 0.298 0.000
Chapter V Mental and behavioural disorders
0.701 0.299 0.000
C78.2 Secondary malignant neoplasm of pleura
0.700 0.300 0.000
O80-O84 Delivery
0.700 0.300 0.000
I05-I09 Chronic rheumatic heart diseases
0.699 0.301 0.000
M17.5 Other secondary gonarthrosis
0.699 0.301 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.699 0.301 0.000
M17.3 Other posttraumatic gonarthrosis
0.699 0.301 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.699 0.301 0.000
N32.3 Diverticulum of bladder
0.699 0.301 0.000
M23.8 Other internal derangements of knee
0.699 0.301 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.698 0.302 0.000
R36 Urethral discharge
0.698 0.302 0.000
R34 Anuria and oliguria
0.698 0.302 0.000
M80-M85 Disorders of bone density and structure
0.694 0.306 0.000
N30.8 Other cystitis
0.693 0.307 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.692 0.308 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.691 0.309 0.000
I49 Other cardiac arrhythmias
0.691 0.309 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.690 0.310 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.689 0.311 0.000
C77.0 Lymph nodes of head, face and neck
0.689 0.311 0.000
N20 Calculus of kidney and ureter
0.688 0.312 0.000
R52 Pain, not elsewhere classified
0.688 0.312 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.312 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.687 0.312 0.000
C34 Malignant neoplasm of bronchus and lung
0.687 0.313 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.687 0.313 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.686 0.314 0.000
C67 Malignant neoplasm of bladder
0.686 0.314 0.000
M06 Other rheumatoid arthritis
0.686 0.314 0.000
R21 Rash and other nonspecific skin eruption
0.685 0.314 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.685 0.315 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.685 0.315 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.685 0.315 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.685 0.315 0.000
Z87.0 Personal history of diseases of the respiratory system
0.684 0.316 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.683 0.317 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.683 0.317 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.683 0.317 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.683 0.317 0.000
O36 Maternal care for other known or suspected foetal problems
0.683 0.317 0.000
I50 Heart failure
0.683 0.317 0.000
J47 Bronchiectasis
0.681 0.319 0.000
H25 Senile cataract
0.681 0.319 0.000
C51-C58 Malignant neoplasms of female genital organs
0.681 0.319 0.000
N00-N08 Glomerular diseases
0.680 0.320 0.000
S40-S49 Injuries to the shoulder and upper arm
0.680 0.320 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.680 0.320 0.000
I70 Atherosclerosis
0.680 0.320 0.000
I74 Arterial embolism and thrombosis
0.679 0.321 0.000
I60 Subarachnoid haemorrhage
0.679 0.321 0.000
I62 Other nontraumatic intracranial haemorrhage
0.679 0.321 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.678 0.322 0.000
H33.0 Retinal detachment with retinal break
0.677 0.323 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.677 0.323 0.000
N30.2 Other chronic cystitis
0.676 0.323 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.676 0.324 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.675 0.325 0.000
M77 Other enthesopathies
0.674 0.326 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.674 0.326 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.674 0.326 0.000
M23.4 Loose body in knee
0.674 0.326 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.673 0.327 0.000
O70.9 Perineal laceration during delivery, unspecified
0.673 0.327 0.000
O70.3 Fourth degree perineal laceration during delivery
0.673 0.327 0.000
O70.2 Third degree perineal laceration during delivery
0.673 0.327 0.000
M25.9 Joint disorder, unspecified
0.672 0.328 0.000
M25.8 Other specified joint disorders
0.672 0.328 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.672 0.328 0.000
M25.3 Other instability of joint
0.672 0.328 0.000
M25.2 Flail joint
0.672 0.328 0.000
M25.1 Fistula of joint
0.672 0.328 0.000
M25.0 Haemarthrosis
0.672 0.328 0.000
M31.3 Wegener's granulomatosis
0.671 0.329 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.670 0.330 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.670 0.330 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.670 0.330 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.670 0.330 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.670 0.330 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.670 0.330 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.669 0.331 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.669 0.331 0.000
I61 Intracerebral haemorrhage
0.669 0.331 0.000
J42 Unspecified chronic bronchitis
0.669 0.331 0.000
R23 Other skin changes
0.668 0.332 0.000
Z99.2 Dependence on renal dialysis
0.668 0.332 0.000
Z92.9 Personal history of medical treatment, unspecified
0.667 0.332 0.000
Z92.8 Personal history of other medical treatment
0.667 0.332 0.000
Z92.5 Personal history of rehabilitation measures
0.667 0.332 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.667 0.333 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
C60-C63 Malignant neoplasms of male genital organs
0.667 0.333 0.000
I42 Cardiomyopathy
0.666 0.333 0.000
S90-S99 Injuries to the ankle and foot
0.666 0.333 0.000
O71.4 Obstetric high vaginal laceration alone
0.666 0.334 0.000
C77.2 Intra-abdominal lymph nodes
0.666 0.334 0.000
I12 Hypertensive renal disease
0.665 0.335 0.000
N37 Urethral disorders in diseases classified elsewhere
0.664 0.335 0.000
N34 Urethritis and urethral syndrome
0.664 0.335 0.000
N33 Bladder disorders in diseases classified elsewhere
0.664 0.335 0.000
Z73 Problems related to life-management difficulty
0.664 0.336 0.000
R45 Symptoms and signs involving emotional state
0.662 0.338 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.661 0.339 0.000
I78 Diseases of capillaries
0.661 0.339 0.000
N99-N99 Other disorders of the genitourinary system
0.660 0.340 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.659 0.341 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.657 0.343 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.657 0.343 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.657 0.343 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.656 0.344 0.000
J41 Simple and mucopurulent chronic bronchitis
0.655 0.345 0.000
J46 Status asthmaticus
0.655 0.345 0.000
O63.9 Long labour, unspecified
0.655 0.345 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.655 0.345 0.000
H54 Blindness and low vision
0.655 0.345 0.000
R87.6 Abnormal cytological findings
0.655 0.345 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.654 0.346 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.654 0.346 0.000
O20 Haemorrhage in early pregnancy
0.653 0.347 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.652 0.348 0.000
S70-S79 Injuries to the hip and thigh
0.652 0.348 0.000
M18 Arthrosis of first carpometacarpal joint
0.651 0.349 0.000
S80-S89 Injuries to the knee and lower leg
0.651 0.349 0.000
Z38 Liveborn infants according to place of birth
0.651 0.349 0.000
Z32 Pregnancy examination and test
0.651 0.349 0.000
Z31 Procreative management
0.651 0.349 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.651 0.349 0.000
T79-T79 Certain early complications of trauma
0.650 0.350 0.000
T66-T78 Other and unspecified effects of external causes
0.650 0.350 0.000
T33-T35 Frostbite
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.650 0.350 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.650 0.350 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.650 0.350 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.650 0.350 0.000
T00-T07 Injuries involving multiple body regions
0.650 0.350 0.000
S10-S19 Injuries to the neck
0.650 0.350 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.649 0.351 0.000
N39.4 Other specified urinary incontinence
0.649 0.351 0.000
N36 Other disorders of urethra
0.648 0.352 0.000
M23.9 Internal derangement of knee, unspecified
0.648 0.352 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.648 0.352 0.000
M23.5 Chronic instability of knee
0.648 0.352 0.000
M23.1 Discoid meniscus (congenital)
0.648 0.352 0.000
M23.0 Cystic meniscus
0.648 0.352 0.000
M25.79 Osteophyte (Site unspecified)
0.648 0.352 0.000
M25.78 Osteophyte (Other)
0.648 0.352 0.000
M25.73 Osteophyte (Forearm)
0.648 0.352 0.000
M25.72 Osteophyte (Upper arm)
0.648 0.352 0.000
M25.71 Osteophyte (Shoulder region)
0.648 0.352 0.000
M25.70 Osteophyte (Multiple sites)
0.648 0.352 0.000
Z39 Postpartum care and examination
0.648 0.352 0.000
J20-J22 Other acute lower respiratory infections
0.648 0.352 0.000
M10 Gout
0.648 0.352 0.000
I24.1 Dressler's syndrome
0.647 0.353 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.646 0.353 0.000
N60-N64 Disorders of breast
0.647 0.353 0.000
J17 Pneumonia in diseases classified elsewhere
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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