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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78894544
log Bayes Factor = 7.29453
Chromosome 8   position 138,323,083  (GRCh37) Explore rs78894544 on Ensembl!
Variant rs78894544 is part of Cluster X0050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.985 0.015 0.000
Chapter VIII Diseases of the ear and mastoid process
0.983 0.017 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.981 0.019 0.000
S60-S69 Injuries to the wrist and hand
0.979 0.021 0.000
C78.7 Secondary malignant neoplasm of liver
0.976 0.024 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.975 0.025 0.000
Chapter I Certain infectious and parasitic diseases
0.974 0.026 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.973 0.027 0.000
C34 Malignant neoplasm of bronchus and lung
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.970 0.030 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
C18 Malignant neoplasm of colon
0.962 0.038 0.000
C78.0 Secondary malignant neoplasm of lung
0.956 0.044 0.000
S64 Injury of nerves at wrist and hand level
0.955 0.045 0.000
G90-G99 Other disorders of the nervous system
0.951 0.049 0.000
C34.1 Upper lobe, bronchus or lung
0.950 0.050 0.000
C18.7 Sigmoid colon
0.944 0.056 0.000
S40-S49 Injuries to the shoulder and upper arm
0.941 0.059 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.934 0.066 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.933 0.067 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
B35-B49 Mycoses
0.917 0.083 0.000
G93 Other disorders of brain
0.916 0.084 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.914 0.086 0.000
S64.4 Injury of digital nerve of other finger
0.914 0.086 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.913 0.087 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.912 0.088 0.000
D10-D36 Benign neoplasms
0.911 0.089 0.000
H65-H75 Diseases of middle ear and mastoid
0.906 0.094 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.903 0.097 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.897 0.103 0.000
M45-M49 Spondylopathies
0.889 0.111 0.000
H60-H62 Diseases of external ear
0.882 0.118 0.000
C34.3 Lower lobe, bronchus or lung
0.881 0.119 0.000
M80-M85 Disorders of bone density and structure
0.878 0.122 0.000
B37 Candidiasis
0.874 0.126 0.000
B25-B34 Other viral diseases
0.872 0.128 0.000
D12.8 Rectum
0.870 0.130 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.869 0.131 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.869 0.131 0.000
A30-A49 Other bacterial diseases
0.866 0.134 0.000
C64-C68 Malignant neoplasms of urinary tract
0.865 0.135 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.863 0.137 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.862 0.138 0.000
H90-H95 Other disorders of ear
0.860 0.140 0.000
C78.2 Secondary malignant neoplasm of pleura
0.855 0.145 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.854 0.146 0.000
S61 Open wound of wrist and hand
0.853 0.147 0.000
M47 Spondylosis
0.853 0.147 0.000
C73 Malignant neoplasm of thyroid gland
0.852 0.148 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.852 0.148 0.000
G12 Spinal muscular atrophy and related syndromes
0.849 0.151 0.000
M81 Osteoporosis without pathological fracture
0.844 0.156 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.841 0.159 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.840 0.160 0.000
C71 Malignant neoplasm of brain
0.839 0.161 0.000
G30-G32 Other degenerative diseases of the nervous system
0.838 0.162 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.837 0.163 0.000
C18.0 Caecum
0.835 0.165 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.833 0.167 0.000
B37.0 Candidal stomatitis
0.831 0.169 0.000
D12.6 Colon, unspecified
0.827 0.173 0.000
K50 Crohn's disease [regional enteritis]
0.827 0.173 0.000
M81.9 Osteoporosis, unspecified
0.826 0.174 0.000
Chapter XX External causes of morbidity and mortality
0.824 0.176 0.000
D10 Benign neoplasm of mouth and pharynx
0.824 0.176 0.000
K50-K52 Noninfective enteritis and colitis
0.823 0.177 0.000
L91 Hypertrophic disorders of skin
0.823 0.177 0.000
Chapter XI Diseases of the digestive system
0.823 0.177 0.000
G93.8 Other specified disorders of brain
0.821 0.179 0.000
S42 Fracture of shoulder and upper arm
0.821 0.179 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.819 0.181 0.000
H71 Cholesteatoma of middle ear
0.817 0.183 0.000
L90 Atrophic disorders of skin
0.814 0.186 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.813 0.187 0.000
K50.1 Crohn's disease of large intestine
0.811 0.189 0.000
K50.9 Crohn's disease, unspecified
0.811 0.189 0.000
A41 Other septicaemia
0.811 0.189 0.000
L81 Other disorders of pigmentation
0.811 0.189 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.809 0.191 0.000
H61 Other disorders of external ear
0.808 0.192 0.000
H92 Otalgia and effusion of ear
0.806 0.194 0.000
K65-K67 Diseases of peritoneum
0.806 0.194 0.000
G12.2 Motor neuron disease
0.805 0.195 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.803 0.197 0.000
B34 Viral infection of unspecified site
0.798 0.201 0.000
M05-M14 Inflammatory polyarthropathies
0.797 0.203 0.000
C77.2 Intra-abdominal lymph nodes
0.796 0.204 0.000
G93.6 Cerebral oedema
0.796 0.204 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.796 0.204 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.795 0.205 0.000
H66 Suppurative and unspecified otitis media
0.795 0.205 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.795 0.205 0.000
B50-B64 Protozoal diseases
0.791 0.209 0.000
C67 Malignant neoplasm of bladder
0.791 0.209 0.000
G93.4 Encephalopathy, unspecified
0.790 0.210 0.000
K66 Other disorders of peritoneum
0.790 0.210 0.000
L90.0 Lichen sclerosus et atrophicus
0.788 0.212 0.000
M60-M63 Disorders of muscles
0.787 0.213 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.787 0.213 0.000
C23 Malignant neoplasm of gallbladder
0.787 0.213 0.000
C18.6 Descending colon
0.786 0.214 0.000
G91 Hydrocephalus
0.784 0.216 0.000
Chapter VII Diseases of the eye and adnexa
0.783 0.217 0.000
S67 Crushing injury of wrist and hand
0.782 0.218 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
D80-D89 Certain disorders involving the immune mechanism
0.782 0.218 0.000
C71.9 Brain, unspecified
0.782 0.218 0.000
G82 Paraplegia and tetraplegia
0.780 0.220 0.000
S65 Injury of blood vessels at wrist and hand level
0.778 0.222 0.000
K66.0 Peritoneal adhesions
0.777 0.223 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.774 0.226 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.774 0.226 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.771 0.229 0.000
S61.0 Open wound of finger(s) without damage to nail
0.770 0.230 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.769 0.231 0.000
D16 Benign neoplasm of bone and articular cartilage
0.768 0.231 0.000
C18.2 Ascending colon
0.767 0.233 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.765 0.235 0.000
S41 Open wound of shoulder and upper arm
0.765 0.235 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.764 0.236 0.000
M06 Other rheumatoid arthritis
0.763 0.237 0.000
C60-C63 Malignant neoplasms of male genital organs
0.763 0.237 0.000
S64.1 Injury of median nerve at wrist and hand level
0.762 0.238 0.000
C16 Malignant neoplasm of stomach
0.758 0.242 0.000
D34 Benign neoplasm of thyroid gland
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.757 0.243 0.000
D86 Sarcoidosis
0.756 0.244 0.000
L81.4 Other melanin hyperpigmentation
0.754 0.246 0.000
C77.5 Intrapelvic lymph nodes
0.752 0.248 0.000
D12.4 Descending colon
0.752 0.248 0.000
C17 Malignant neoplasm of small intestine
0.751 0.249 0.000
L91.0 Keloid scar
0.750 0.250 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.750 0.250 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.749 0.251 0.000
C18.9 Colon, unspecified
0.748 0.252 0.000
L40-L45 Papulosquamous disorders
0.747 0.253 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.746 0.254 0.000
A65-A69 Other spirochaetal diseases
0.744 0.255 0.000
B34.9 Viral infection, unspecified
0.744 0.256 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.743 0.257 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.740 0.260 0.000
C79.6 Secondary malignant neoplasm of ovary
0.740 0.260 0.000
D23 Other benign neoplasms of skin
0.740 0.260 0.000
G11 Hereditary ataxia
0.739 0.261 0.000
S68 Traumatic amputation of wrist and hand
0.739 0.261 0.000
C25 Malignant neoplasm of pancreas
0.736 0.264 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.735 0.265 0.000
M06.9 Rheumatoid arthritis, unspecified
0.735 0.265 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.735 0.265 0.000
M47.8 Other spondylosis
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.732 0.268 0.000
S69 Other and unspecified injuries of wrist and hand
0.731 0.269 0.000
G90 Disorders of autonomic nervous system
0.731 0.269 0.000
S62 Fracture at wrist and hand level
0.728 0.272 0.000
H61.2 Impacted cerumen
0.726 0.274 0.000
C18.3 Hepatic flexure
0.725 0.275 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.725 0.275 0.000
D86.9 Sarcoidosis, unspecified
0.724 0.276 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.724 0.276 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.276 0.000
S60 Superficial injury of wrist and hand
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
D31 Benign neoplasm of eye and adnexa
0.723 0.277 0.000
D23.6 Skin of upper limb, including shoulder
0.721 0.279 0.000
H92.1 Otorrhoea
0.720 0.280 0.000
M47.2 Other spondylosis with radiculopathy
0.720 0.280 0.000
Q50-Q56 Congenital malformations of genital organs
0.719 0.281 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.282 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.284 0.000
D12.5 Sigmoid colon
0.716 0.284 0.000
B37.2 Candidiasis of skin and nail
0.716 0.284 0.000
Q80-Q89 Other congenital malformations
0.714 0.286 0.000
L20-L30 Dermatitis and eczema
0.714 0.286 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
H80-H83 Diseases of inner ear
0.713 0.287 0.000
S64.3 Injury of digital nerve of thumb
0.713 0.287 0.000
D32 Benign neoplasm of meninges
0.713 0.287 0.000
K51 Ulcerative colitis
0.712 0.288 0.000
G82.1 Spastic paraplegia
0.711 0.289 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.710 0.290 0.000
S10-S19 Injuries to the neck
0.707 0.293 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.707 0.293 0.000
B36 Other superficial mycoses
0.707 0.293 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
S40 Superficial injury of shoulder and upper arm
0.706 0.294 0.000
H92.0 Otalgia
0.706 0.294 0.000
C77.9 Lymph node, unspecified
0.705 0.295 0.000
G93.0 Cerebral cysts
0.705 0.295 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.704 0.296 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.704 0.296 0.000
C31 Malignant neoplasm of accessory sinuses
0.704 0.296 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.704 0.296 0.000
C37 Malignant neoplasm of thymus
0.704 0.296 0.000
C33 Malignant neoplasm of trachea
0.704 0.296 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
G95 Other diseases of spinal cord
0.702 0.298 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.701 0.299 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.701 0.299 0.000
M47.9 Spondylosis, unspecified
0.701 0.299 0.000
D12.1 Appendix
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
C80 Malignant neoplasm without specification of site
0.699 0.301 0.000
M47.1 Other spondylosis with myelopathy
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.698 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.301 0.000
A75-A79 Rickettsioses
0.698 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.301 0.000
A15-A19 Tuberculosis
0.698 0.301 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.698 0.302 0.000
Y43 Primarily systemic agents
0.698 0.302 0.000
D17 Benign lipomatous neoplasm
0.697 0.303 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.697 0.303 0.000
D10.3 Other and unspecified parts of mouth
0.696 0.304 0.000
C34.8 Overlapping lesion of bronchus and lung
0.696 0.304 0.000
C34.2 Middle lobe, bronchus or lung
0.696 0.304 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.695 0.305 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.695 0.305 0.000
M45 Ankylosing spondylitis
0.694 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.694 0.306 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.692 0.307 0.000
H66.3 Other chronic suppurative otitis media
0.692 0.308 0.000
G93.3 Postviral fatigue syndrome
0.691 0.309 0.000
C34.0 Main bronchus
0.690 0.309 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.690 0.310 0.000
C18.8 Overlapping lesion of colon
0.690 0.310 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.688 0.312 0.000
H61.8 Other specified disorders of external ear
0.687 0.313 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.687 0.313 0.000
B37.1 Pulmonary candidiasis
0.687 0.313 0.000
L83 Acanthosis nigricans
0.686 0.314 0.000
S42.0 Fracture of clavicle
0.686 0.314 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.686 0.314 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.684 0.315 0.000
S64.8 Injury of other nerves at wrist and hand level
0.684 0.315 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.684 0.315 0.000
C67.2 Lateral wall of bladder
0.684 0.316 0.000
M62 Other disorders of muscle
0.683 0.317 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.682 0.318 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
G92 Toxic encephalopathy
0.682 0.318 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.681 0.319 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.680 0.320 0.000
C82.0 Small cleaved cell, follicular
0.680 0.320 0.000
C18.1 Appendix
0.679 0.321 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.678 0.322 0.000
L84 Corns and callosities
0.678 0.322 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.677 0.323 0.000
S61.1 Open wound of finger(s) with damage to nail
0.677 0.323 0.000
A40 Streptococcal septicaemia
0.676 0.324 0.000
M47.86 Other spondylosis (Lumbar region)
0.676 0.324 0.000
S48 Traumatic amputation of shoulder and upper arm
0.675 0.325 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.675 0.325 0.000
S44 Injury of nerves at shoulder and upper arm level
0.675 0.325 0.000
S47 Crushing injury of shoulder and upper arm
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.674 0.326 0.000
B49 Unspecified mycosis
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.672 0.327 0.000
C18.5 Splenic flexure
0.672 0.327 0.000
D10.5 Other parts of oropharynx
0.672 0.328 0.000
H74 Other disorders of middle ear and mastoid
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T43.2 Other and unspecified antidepressants
0.670 0.330 0.000
S42.2 Fracture of upper end of humerus
0.668 0.332 0.000
H72 Perforation of tympanic membrane
0.667 0.333 0.000
D30 Benign neoplasm of urinary organs
0.667 0.333 0.000
B37.9 Candidiasis, unspecified
0.667 0.333 0.000
Y52 Agents primarily affecting the cardiovascular system
0.667 0.333 0.000
D55-D59 Haemolytic anaemias
0.667 0.333 0.000
C67.8 Overlapping lesion of bladder
0.666 0.334 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.666 0.334 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.665 0.335 0.000
M46 Other inflammatory spondylopathies
0.665 0.335 0.000
L93 Lupus erythematosus
0.664 0.336 0.000
S32 Fracture of lumbar spine and pelvis
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.663 0.336 0.000
M85 Other disorders of bone density and structure
0.663 0.337 0.000
L10-L14 Bullous disorders
0.663 0.337 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.662 0.338 0.000
B65-B83 Helminthiases
0.660 0.339 0.000
B37.4 Candidiasis of other urogenital sites
0.660 0.340 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.660 0.340 0.000
B59 Pneumocystosis
0.659 0.341 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.658 0.342 0.000
B48 Other mycoses, not elsewhere classified
0.657 0.343 0.000
B47 Mycetoma
0.657 0.343 0.000
B46 Zygomycosis
0.657 0.343 0.000
B45 Cryptococcosis
0.657 0.343 0.000
B43 Chromomycosis and phaeomycotic abscess
0.657 0.343 0.000
B42 Sporotrichosis
0.657 0.343 0.000
B41 Paracoccidioidomycosis
0.657 0.343 0.000
B40 Blastomycosis
0.657 0.343 0.000
B39 Histoplasmosis
0.657 0.343 0.000
B38 Coccidioidomycosis
0.657 0.343 0.000
G93.7 Reye's syndrome
0.657 0.343 0.000
G93.5 Compression of brain
0.657 0.343 0.000
H69 Other disorders of Eustachian tube
0.656 0.344 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.655 0.345 0.000
C74 Malignant neoplasm of adrenal gland
0.655 0.345 0.000
T79-T79 Certain early complications of trauma
0.655 0.345 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.655 0.345 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.655 0.345 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.655 0.345 0.000
L94 Other localised connective tissue disorders
0.655 0.345 0.000
L87 Transepidermal elimination disorders
0.655 0.345 0.000
L88 Pyoderma gangrenosum
0.655 0.345 0.000
L86 Keratoderma in diseases classified elsewhere
0.655 0.345 0.000
L80 Vitiligo
0.655 0.345 0.000
G91.9 Hydrocephalus, unspecified
0.654 0.346 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.654 0.346 0.000
K50.0 Crohn's disease of small intestine
0.654 0.346 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.654 0.346 0.000
G14 Postpolio syndrome
0.654 0.346 0.000
G10 Huntington's disease
0.654 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.346 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.653 0.347 0.000
H61.1 Non-infective disorders of pinna
0.653 0.347 0.000
D29 Benign neoplasm of male genital organs
0.653 0.347 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.653 0.347 0.000
D19 Benign neoplasm of mesothelial tissue
0.653 0.347 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.653 0.347 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
C32 Malignant neoplasm of larynx
0.651 0.349 0.000
M00-M03 Infectious arthropathies
0.650 0.350 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.650 0.350 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.649 0.350 0.000
H68 Eustachian salpingitis and obstruction
0.649 0.350 0.000
H67 Otitis media in diseases classified elsewhere
0.649 0.350 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.649 0.351 0.000
C34.9 Bronchus or lung, unspecified
0.649 0.351 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.648 0.352 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.647 0.352 0.000
C70 Malignant neoplasm of meninges
0.647 0.352 0.000
H90 Conductive and sensorineural hearing loss
0.647 0.353 0.000
C71.8 Overlapping lesion of brain
0.647 0.353 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.647 0.353 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.646 0.353 0.000
C71.3 Parietal lobe
0.646 0.354 0.000
T43.6 Psychostimulants with abuse potential
0.646 0.354 0.000
Y43.3 Other antineoplastic drugs
0.645 0.355 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.645 0.355 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.643 0.357 0.000
T11 Other injuries of upper limb, level unspecified
0.643 0.357 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.641 0.359 0.000
G93.2 Benign intracranial hypertension
0.641 0.359 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.641 0.359 0.000
M91-M94 Chondropathies
0.641 0.359 0.000
H70 Mastoiditis and related conditions
0.640 0.359 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.640 0.360 0.000
G80 Infantile cerebral palsy
0.639 0.360 0.000
C67.5 Bladder neck
0.638 0.362 0.000
M49 Spondylopathies in diseases classified elsewhere
0.637 0.363 0.000
T40.4 Other synthetic narcotics
0.636 0.364 0.000
T58 Toxic effect of carbon monoxide
0.636 0.364 0.000
D16.4 Bones of skull and face
0.636 0.364 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.635 0.365 0.000
H60 Otitis externa
0.635 0.365 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.634 0.365 0.000
C61 Malignant neoplasm of prostate
0.634 0.366 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.634 0.366 0.000
A41.8 Other specified septicaemia
0.633 0.366 0.000
V10-V19 Pedal cyclist injured in transport accident
0.633 0.367 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.633 0.367 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.633 0.367 0.000
M82 Osteoporosis in diseases classified elsewhere
0.632 0.368 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.632 0.368 0.000
D36 Benign neoplasm of other and unspecified sites
0.632 0.368 0.000
K65 Peritonitis
0.632 0.368 0.000
G11.4 Hereditary spastic paraplegia
0.632 0.368 0.000
D60-D64 Aplastic and other anaemias
0.631 0.369 0.000
T14 Injury of unspecified body region
0.630 0.370 0.000
M83 Adult osteomalacia
0.629 0.370 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.629 0.371 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.629 0.371 0.000
W50-W64 Exposure to animate mechanical forces
0.629 0.371 0.000
B25 Cytomegaloviral disease
0.628 0.372 0.000
H93 Other disorders of ear, not elsewhere classified
0.628 0.372 0.000
L43 Lichen planus
0.627 0.373 0.000
B37.7 Candidal septicaemia
0.627 0.373 0.000
B37.6 Candidal endocarditis
0.627 0.373 0.000
B37.5 Candidal meningitis
0.627 0.373 0.000
A48 Other bacterial diseases, not elsewhere classified
0.627 0.373 0.000
B35 Dermatophytosis
0.627 0.373 0.000
S31 Open wound of abdomen, lower back and pelvis
0.626 0.374 0.000
C45 Mesothelioma
0.626 0.374 0.000
B33 Other viral diseases, not elsewhere classified
0.625 0.375 0.000
B30 Viral conjunctivitis
0.625 0.375 0.000
B27 Infectious mononucleosis
0.625 0.375 0.000
B26 Mumps
0.625 0.375 0.000
C69 Malignant neoplasm of eye and adnexa
0.625 0.375 0.000
C77.4 Inguinal and lower limb lymph nodes
0.625 0.375 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.624 0.376 0.000
C65 Malignant neoplasm of renal pelvis
0.624 0.376 0.000
D23.1 Skin of eyelid, including canthus
0.623 0.377 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.623 0.377 0.000
Q35-Q37 Cleft lip and cleft palate
0.623 0.377 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.623 0.377 0.000
B44 Aspergillosis
0.623 0.377 0.000
D10.0 Lip
0.622 0.377 0.000
H66.9 Otitis media, unspecified
0.622 0.377 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.622 0.378 0.000
A44 Bartonellosis
0.621 0.379 0.000
A43 Nocardiosis
0.621 0.379 0.000
A42 Actinomycosis
0.621 0.379 0.000
A39 Meningococcal infection
0.621 0.379 0.000
A37 Whooping cough
0.621 0.379 0.000
A36 Diphtheria
0.621 0.379 0.000
A32 Listeriosis
0.621 0.379 0.000
A31 Infection due to other mycobacteria
0.621 0.379 0.000
A30 Leprosy [Hansen's disease]
0.621 0.379 0.000
A38 Scarlet fever
0.621 0.379 0.000
A35 Other tetanus
0.621 0.379 0.000
A34 Obstetrical tetanus
0.621 0.379 0.000
A33 Tetanus neonatorum
0.621 0.379 0.000
D10.1 Tongue
0.621 0.379 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.620 0.380 0.000
C66 Malignant neoplasm of ureter
0.620 0.380 0.000
D18 Haemangioma and lymphangioma, any site
0.620 0.380 0.000
Q60-Q64 Congenital malformations of the urinary system
0.619 0.381 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.619 0.381 0.000
L85 Other epidermal thickening
0.619 0.381 0.000
T40.2 Other opioids
0.618 0.382 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.618 0.382 0.000
T40.6 Other and unspecified narcotics
0.618 0.382 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.618 0.382 0.000
C95 Leukaemia of unspecified cell type
0.618 0.382 0.000
C94 Other leukaemias of specified cell type
0.618 0.382 0.000
C93 Monocytic leukaemia
0.618 0.382 0.000
C86 Other specified types of T/NK-cell lymphoma
0.618 0.382 0.000
D12.9 Anus and anal canal
0.617 0.383 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.617 0.383 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.616 0.384 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.616 0.384 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.616 0.384 0.000
L91.8 Other hypertrophic disorders of skin
0.616 0.384 0.000
H50 Other strabismus
0.616 0.384 0.000
C21 Malignant neoplasm of anus and anal canal
0.615 0.384 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.615 0.385 0.000
S42.1 Fracture of scapula
0.615 0.385 0.000
C77.1 Intrathoracic lymph nodes
0.612 0.388 0.000
C71.1 Frontal lobe
0.612 0.388 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.611 0.389 0.000
D86.0 Sarcoidosis of lung
0.611 0.389 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.611 0.389 0.000
G82.2 Paraplegia, unspecified
0.610 0.390 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.609 0.391 0.000
M06.3 Rheumatoid nodule
0.609 0.391 0.000
G12.9 Spinal muscular atrophy, unspecified
0.609 0.391 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.609 0.391 0.000
G12.1 Other inherited spinal muscular atrophy
0.609 0.391 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.609 0.391 0.000
V20-V29 Motorcycle rider injured in transport accident
0.609 0.391 0.000
M62.8 Other specified disorders of muscle
0.608 0.392 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.607 0.393 0.000
D32.9 Meninges, unspecified
0.606 0.394 0.000
M81.8 Other osteoporosis
0.605 0.395 0.000
M81.6 Localised osteoporosis [Lequesne]
0.605 0.395 0.000
M81.5 Idiopathic osteoporosis
0.605 0.395 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.605 0.395 0.000
M81.2 Osteoporosis of disuse
0.605 0.395 0.000
M81.1 Postoophorectomy osteoporosis
0.605 0.395 0.000
M81.0 Postmenopausal osteoporosis
0.605 0.395 0.000
V40-V49 Car occupant injured in transport accident
0.605 0.395 0.000
L29 Pruritus
0.604 0.396 0.000
C16.5 Lesser curvature of stomach, unspecified
0.603 0.396 0.000
K51.9 Ulcerative colitis, unspecified
0.603 0.397 0.000
C77.8 Lymph nodes of multiple regions
0.603 0.397 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.603 0.397 0.000
T50.8 Diagnostic agents
0.603 0.397 0.000
T50.7 Analeptics and opioid receptor antagonists
0.603 0.397 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.603 0.397 0.000
T50.5 Appetite depressants
0.603 0.397 0.000
T50.4 Drugs affecting uric acid metabolism
0.603 0.397 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.603 0.397 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.603 0.397 0.000
T50.1 Loop [high-ceiling] diuretics
0.603 0.397 0.000
T50.0 Mineralocorticoids and their antagonists
0.603 0.397 0.000
D22 Melanocytic naevi
0.602 0.398 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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