TreeWAS – Variant ID: rs7896600

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E10.9 Without complications	0.999	0.001	0.000
E11.4 With neurological complications	0.997	0.003	0.000
E10.3 With ophthalmic complications	0.984	0.016	0.000
E11.3 With ophthalmic complications	0.934	0.066	0.000
E11.0 With coma	0.869	0.131	0.000
E10.5 With peripheral circulatory complications	0.851	0.149	0.000
E11.6 With other specified complications	0.844	0.156	0.000
E10.8 With unspecified complications	0.834	0.166	0.000
E14 Unspecified diabetes mellitus	0.820	0.180	0.000
E11.8 With unspecified complications	0.753	0.247	0.000
E10.4 With neurological complications	0.747	0.253	0.000
E11.5 With peripheral circulatory complications	0.736	0.264	0.000
E10.2 With renal complications	0.719	0.281	0.000
E11.7 With multiple complications	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E14.3 With ophthalmic complications	0.709	0.291	0.000
E13 Other specified diabetes mellitus	0.702	0.298	0.000
I25.1 Atherosclerotic heart disease	0.696	0.304	0.000
E11.2 With renal complications	0.696	0.304	0.000
E14.9 Without complications	0.679	0.321	0.000
E10.1 With ketoacidosis	0.665	0.335	0.000
E10.0 With coma	0.664	0.336	0.000
I25 Chronic ischaemic heart disease	0.662	0.338	0.000
I20-I25 Ischaemic heart diseases	0.658	0.342	0.000
I21 Acute myocardial infarction	0.654	0.346	0.000
I21.9 Acute myocardial infarction, unspecified	0.649	0.351	0.000
E10.6 With other specified complications	0.643	0.357	0.000
E14.8 With unspecified complications	0.606	0.394	0.000
E14.7 With multiple complications	0.588	0.412	0.000
E14.6 With other specified complications	0.588	0.412	0.000
E14.0 With coma	0.588	0.412	0.000
E14.2 Withrenal complications	0.585	0.414	0.000
I24 Other acute ischaemic heart diseases	0.583	0.417	0.000
I25.4 Coronary artery aneurysm	0.575	0.425	0.000
E14.4 With neurological complications	0.569	0.430	0.000
I22 Subsequent myocardial infarction	0.550	0.450	0.000
I27 Other pulmonary heart diseases	0.549	0.451	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.533	0.467	0.000
E14.5 With peripheral circulatory complications	0.532	0.468	0.000
I27.2 Other secondary pulmonary hypertension	0.525	0.475	0.000
I21.4 Acute subendocardial myocardial infarction	0.523	0.477	0.000
E13.3 With ophthalmic complications	0.521	0.479	0.000
I27.0 Primary pulmonary hypertension	0.520	0.480	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.520	0.480	0.000
I27.8 Other specified pulmonary heart diseases	0.518	0.482	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.518	0.482	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.516	0.484	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E13.8 With unspecified complications	0.503	0.497	0.000
E13.7 With multiple complications	0.503	0.497	0.000
E13.6 With other specified complications	0.503	0.497	0.000
E13.5 With peripheral circulatory complications	0.503	0.497	0.000
E13.4 With neurological complications	0.503	0.497	0.000
E13.2 With renal complications	0.503	0.497	0.000
E13.1 With ketoacidosis	0.503	0.497	0.000
E13.0 With coma	0.503	0.497	0.000
E11.1 With ketoacidosis	0.502	0.497	0.000
I27.9 Pulmonary heart disease, unspecified	0.497	0.503	0.000
Chapter IX Diseases of the circulatory system	0.496	0.504	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.494	0.506	0.000
I25.6 Silent myocardial ischaemia	0.475	0.525	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.474	0.526	0.000
I23 Certain current complications following acute myocardial infarction	0.471	0.529	0.000
E14.1 With ketoacidosis	0.471	0.529	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.469	0.531	0.000
E13.9 Without complications	0.467	0.533	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.463	0.537	0.000
I25.3 Aneurysm of heart	0.455	0.545	0.000
I28 Other diseases of pulmonary vessels	0.449	0.551	0.000
I10-I15 Hypertensive diseases	0.448	0.552	0.000
I24.1 Dressler's syndrome	0.437	0.562	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.431	0.569	0.000
I22.8 Subsequent myocardial infarction of other sites	0.427	0.573	0.000
I25.5 Ischaemic cardiomyopathy	0.425	0.575	0.000
I25.2 Old myocardial infarction	0.424	0.576	0.000
I11 Hypertensive heart disease	0.419	0.581	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.419	0.581	0.000
I15 Secondary hypertension	0.405	0.594	0.000
I05-I09 Chronic rheumatic heart diseases	0.401	0.599	0.000
I28.8 Other specified diseases of pulmonary vessels	0.400	0.600	0.000
I27.1 Kyphoscoliotic heart disease	0.394	0.606	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.373	0.627	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.367	0.633	0.000
I07 Rheumatic tricuspid valve diseases	0.366	0.634	0.000
I00-I02 Acute rheumatic fever	0.365	0.634	0.000
I15.1 Hypertension secondary to other renal disorders	0.362	0.638	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.346	0.654	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.342	0.658	0.000
I06 Rheumatic aortic valve diseases	0.342	0.658	0.000
I07.1 Tricuspid insufficiency	0.341	0.659	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.338	0.662	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.338	0.662	0.000
I23.8 Other current complications following acute myocardial infarction	0.337	0.663	0.000
I15.8 Other secondary hypertension	0.333	0.667	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.322	0.678	0.000
I28.1 Aneurysm of pulmonary artery	0.322	0.678	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.322	0.678	0.000
I13 Hypertensive heart and renal disease	0.321	0.679	0.000
I12 Hypertensive renal disease	0.312	0.688	0.000
I24.8 Other forms of acute ischaemic heart disease	0.308	0.692	0.000
I06.0 Rheumatic aortic stenosis	0.301	0.699	0.000
I15.2 Hypertension secondary to endocrine disorders	0.291	0.709	0.000
I15.0 Renovascular hypertension	0.291	0.709	0.000
I15.9 Seconday hypertension, unspecified	0.280	0.720	0.000
I09 Other rheumatic heart diseases	0.272	0.727	0.000
I00 Rheumatic fever without mention of heart involvement	0.272	0.728	0.000
I07.9 Tricuspid valve disease, unspecified	0.262	0.738	0.000
I07.8 Other tricuspid valve diseases	0.262	0.738	0.000
I07.2 Tricuspid stenosis with insufficiency	0.262	0.738	0.000
I07.0 Tricuspid stenosis	0.262	0.738	0.000
I02 Rheumatic chorea	0.262	0.738	0.000
I01 Rheumatic fever with heart involvement	0.262	0.738	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.245	0.754	0.000
I06.8 Other rheumatic aortic valve diseases	0.245	0.754	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.245	0.754	0.000
I06.1 Rheumatic aortic insufficiency	0.245	0.754	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.242	0.758	0.000
I12.0 Hypertensive renal disease with renal failure	0.237	0.763	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.230	0.769	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.230	0.769	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.230	0.769	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.230	0.769	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.213	0.787	0.000
I26 Pulmonary embolism	0.207	0.793	0.000
I08 Multiple valve diseases	0.199	0.801	0.000
I12.9 Hypertensive renal disease without renal failure	0.198	0.802	0.000
I09.8 Other specified rheumatic heart diseases	0.195	0.804	0.000
I09.2 Chronic rheumatic pericarditis	0.195	0.804	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.195	0.804	0.000
I09.0 Rheumatic myocarditis	0.195	0.804	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.188	0.812	0.000
I01.8 Other acute rheumatic heart disease	0.188	0.812	0.000
I01.2 Acute rheumatic myocarditis	0.188	0.812	0.000
I01.1 Acute rheumatic endocarditis	0.188	0.812	0.000
I01.0 Acute rheumatic pericarditis	0.188	0.812	0.000
I02.9 Rheumatic chorea without heart involvement	0.188	0.812	0.000
I02.0 Rheumatic chorea with heart involvement	0.188	0.812	0.000
I05 Rheumatic mitral valve diseases	0.188	0.812	0.000
I09.9 Rheumatic heart disease, unspecified	0.181	0.819	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.169	0.831	0.000
I08.9 Multiple valve disease, unspecified	0.155	0.845	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.144	0.856	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.136	0.864	0.000
I60-I69 Cerebrovascular diseases	0.135	0.865	0.000
I05.8 Other mitral valve diseases	0.135	0.865	0.000
I61 Intracerebral haemorrhage	0.134	0.866	0.000
I05.9 Mitral valve disease, unspecified	0.134	0.866	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.133	0.867	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.131	0.869	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.121	0.879	0.000
I05.0 Mitral stenosis	0.119	0.880	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.118	0.882	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.116	0.884	0.000
I05.2 Mitral stenosis with insufficiency	0.114	0.885	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.108	0.892	0.000
I69 Sequelae of cerebrovascular disease	0.106	0.894	0.000
I05.1 Rheumatic mitral insufficiency	0.102	0.898	0.000
I63 Cerebral infarction	0.100	0.900	0.000
I69.3 Sequelae of cerebral infarction	0.098	0.902	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.096	0.904	0.000
I63.8 Other cerebral infarction	0.095	0.905	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.094	0.906	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.093	0.907	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.092	0.908	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.091	0.908	0.000
N19 Unspecified renal failure	0.088	0.912	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.087	0.913	0.000
I08.8 Other multiple valve diseases	0.085	0.915	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.085	0.915	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.084	0.915	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.083	0.917	0.000
N17-N19 Renal failure	0.083	0.917	0.000
N17 Acute renal failure	0.082	0.918	0.000
N17.9 Acute renal failure, unspecified	0.082	0.918	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.079	0.921	0.000
I99 Other and unspecified disorders of circulatory system	0.078	0.922	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.078	0.922	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.077	0.923	0.000
N18 Chronic renal failure	0.074	0.926	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.072	0.928	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.072	0.928	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.070	0.930	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.067	0.933	0.000
N18.4 Chronic kidney disease, stage 4	0.067	0.933	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.066	0.933	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.066	0.933	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.066	0.933	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.066	0.934	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.066	0.934	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.066	0.934	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.066	0.934	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.064	0.936	0.000
N17.8 Other acute renal failure	0.064	0.936	0.000
N18.5 Chronic kidney disease, stage 5	0.064	0.936	0.000
N18.0 End-stage renal disease	0.063	0.937	0.000
I68.0 Cerebral amyloid angiopathy	0.061	0.938	0.000
N18.8 Other chronic renal failure	0.061	0.939	0.000
I97.1 Other functional disturbances following cardiac surgery	0.061	0.939	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.059	0.941	0.000
N17.2 Acute renal failure with medullary necrosis	0.059	0.941	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.059	0.941	0.000
I61.8 Other intracerebral haemorrhage	0.058	0.941	0.000
I33.0 Acute and subacute infective endocarditis	0.057	0.942	0.000
I30-I52 Other forms of heart disease	0.058	0.942	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.057	0.943	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.057	0.943	0.000
I97.0 Postcardiotomy syndrome	0.057	0.943	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.057	0.943	0.000
I33 Acute and subacute endocarditis	0.057	0.943	0.000
I20 Angina pectoris	0.056	0.944	0.000
N17.0 Acute renal failure with tubular necrosis	0.055	0.945	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.055	0.945	0.000
N18.1 Chronic kidney disease, stage 1	0.054	0.946	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.054	0.946	0.000
I50.0 Congestive heart failure	0.054	0.946	0.000
I50 Heart failure	0.053	0.947	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.052	0.948	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.052	0.948	0.000
I51 Complications and ill-defined descriptions of heart disease	0.051	0.949	0.000
I62 Other nontraumatic intracranial haemorrhage	0.050	0.950	0.000
I08.0 Disorders of both mitral and aortic valves	0.049	0.951	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.048	0.952	0.000
I65.1 Occlusion and stenosis of basilar artery	0.048	0.952	0.000
I38 Endocarditis, valve unspecified	0.047	0.953	0.000
I51.8 Other ill-defined heart diseases	0.046	0.954	0.000
N18.9 Chronic renal failure, unspecified	0.045	0.955	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.044	0.955	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.043	0.956	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.042	0.957	0.000
I47.2 Ventricular tachycardia	0.042	0.958	0.000
I51.4 Myocarditis, unspecified	0.042	0.958	0.000
I47 Paroxysmal tachycardia	0.042	0.958	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.041	0.958	0.000
I52 Other heart disorders in diseases classified elsewhere	0.041	0.958	0.000
I48 Atrial fibrillation and flutter	0.041	0.958	0.000
I41 Myocarditis in diseases classified elsewhere	0.041	0.958	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.041	0.958	0.000
I32 Pericarditis in diseases classified elsewhere	0.041	0.958	0.000
I40 Acute myocarditis	0.041	0.959	0.000
I50.1 Left ventricular failure	0.041	0.959	0.000
I51.9 Heart disease, unspecified	0.041	0.959	0.000
I33.9 Acute endocarditis, unspecified	0.040	0.960	0.000
I37 Pulmonary valve disorders	0.040	0.960	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.039	0.960	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.039	0.960	0.000
I98.0 Cardiovascular syphilis	0.039	0.960	0.000
I30 Acute pericarditis	0.040	0.960	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.039	0.960	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.039	0.961	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.039	0.961	0.000
I51.6 Cardiovascular disease, unspecified	0.039	0.961	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.038	0.962	0.000
I51.5 Myocardial degeneration	0.037	0.963	0.000
N18.2 Chronic kidney disease, stage 2	0.037	0.963	0.000
I62.1 Nontraumatic extradural haemorrhage	0.036	0.963	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.036	0.963	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.036	0.964	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.035	0.965	0.000
Z95.1 Presence of aortocoronary bypass graft	0.034	0.966	0.000
I36 Nonrheumatic tricuspid valve disorders	0.034	0.966	0.000
E20-E35 Disorders of other endocrine glands	0.034	0.966	0.000
E34 Other endocrine disorders	0.034	0.966	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.033	0.966	0.000
I35 Nonrheumatic aortic valve disorders	0.033	0.967	0.000
I20.0 Unstable angina	0.033	0.967	0.000
E21.0 Primary hyperparathyroidism	0.033	0.967	0.000
I35.9 Aortic valve disorder, unspecified	0.033	0.967	0.000
I51.0 Cardiac septal defect, acquired	0.032	0.967	0.000
I60 Subarachnoid haemorrhage	0.033	0.967	0.000
E21.3 Hyperparathyroidism, unspecified	0.032	0.968	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.031	0.968	0.001
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.031	0.968	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.031	0.968	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.031	0.968	0.000
E34.0 Carcinoid syndrome	0.031	0.969	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.031	0.969	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.030	0.970	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.030	0.970	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.030	0.970	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.030	0.970	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.030	0.970	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.030	0.970	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.030	0.970	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.030	0.970	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.030	0.970	0.000
I48.4 Atypical atrial flutter	0.030	0.970	0.000
I48.3 Typical atrial flutter	0.030	0.970	0.000
I48.2 Chronic atrial fibrillation	0.030	0.970	0.000
I48.1 Persistent atrial fibrillation	0.030	0.970	0.000
I48.0 Paroxysmal atrial fibrillation	0.030	0.970	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.030	0.970	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.030	0.970	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.030	0.970	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.030	0.970	0.000
I40.9 Acute myocarditis, unspecified	0.030	0.970	0.000
I40.8 Other acute myocarditis	0.030	0.970	0.000
I40.1 Isolated myocarditis	0.030	0.970	0.000
E34.9 Endocrine disorder, unspecified	0.030	0.970	0.000
I40.0 Infective myocarditis	0.029	0.970	0.000
I30.9 Acute pericarditis, unspecified	0.029	0.971	0.000
I10 Essential (primary) hypertension	0.029	0.971	0.000
I37.9 Pulmonary valve disorder, unspecified	0.029	0.971	0.000
I37.8 Other pulmonary valve disorders	0.029	0.971	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.029	0.971	0.000
I37.0 Pulmonary valve stenosis	0.029	0.971	0.000
I30.8 Other forms of acute pericarditis	0.028	0.971	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.028	0.971	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.029	0.971	0.000
I46 Cardiac arrest	0.028	0.972	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.027	0.973	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.027	0.973	0.000
I37.1 Pulmonary valve insufficiency	0.027	0.973	0.000
E34.3 Short stature, not elsewhere classified	0.027	0.973	0.000
I47.0 Reentry ventricular arrhythmia	0.027	0.973	0.000
E21.2 Other hyperparathyroidism	0.026	0.974	0.000
E34.8 Other specified endocrine disorders	0.026	0.974	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.026	0.974	0.000
I30.1 Infective pericarditis	0.026	0.974	0.000
E65-E68 Obesity and other hyperalimentation	0.026	0.974	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.026	0.974	0.000
E21.4 Other specified disorders of parathyroid gland	0.025	0.974	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.025	0.975	0.000
E29 Testicular dysfunction	0.025	0.975	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.024	0.975	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.024	0.975	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.024	0.975	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.024	0.975	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.025	0.975	0.000
E32 Diseases of thymus	0.025	0.975	0.000
E31 Polyglandular dysfunction	0.025	0.975	0.000
E30 Disorders of puberty, not elsewhere classified	0.025	0.975	0.000
E34.5 Androgen resistance syndrome	0.025	0.975	0.000
E34.4 Constitutional tall stature	0.025	0.975	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.025	0.975	0.000
E34.1 Other hypersecretion of intestinal hormones	0.025	0.975	0.000
E40-E46 Malnutrition	0.024	0.975	0.000
E20 Hypoparathyroidism	0.024	0.976	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.024	0.976	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.024	0.976	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.023	0.976	0.000
E25 Adrenogenital disorders	0.023	0.976	0.000
N18.3 Chronic kidney disease, stage 3	0.023	0.977	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.022	0.978	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.022	0.978	0.000
E65 Localised adiposity	0.022	0.978	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.022	0.978	0.000
I42 Cardiomyopathy	0.022	0.978	0.000
I35.8 Other aortic valve disorders	0.022	0.978	0.000
I72 Other aneurysm	0.022	0.978	0.000
E26 Hyperaldosteronism	0.021	0.979	0.000
I51.7 Cardiomegaly	0.021	0.979	0.000
I60.8 Other subarachnoid haemorrhage	0.021	0.979	0.000
E24 Cushing's syndrome	0.020	0.979	0.000
I46.1 Sudden cardiac death, so described	0.020	0.980	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.020	0.980	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.020	0.980	0.000
I46.0 Cardiac arrest with successful resuscitation	0.020	0.980	0.000
E28 Ovarian dysfunction	0.020	0.980	0.000
I42.9 Cardiomyopathy, unspecified	0.019	0.981	0.000
I20.8 Other forms of angina pectoris	0.019	0.981	0.000
E67 Other hyperalimentation	0.019	0.981	0.000
E68 Sequelae of hyperalimentation	0.019	0.981	0.000
E15 Nondiabetic hypoglycaemic coma	0.018	0.981	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.018	0.981	0.000
E29.1 Testicular hypofunction	0.018	0.981	0.000
I70 Atherosclerosis	0.018	0.981	0.000
E29.9 Testicular dysfunction, unspecified	0.018	0.982	0.000
E29.8 Other testicular dysfunction	0.018	0.982	0.000
E29.0 Testicular hyperfunction	0.018	0.982	0.000
E30.9 Disorder of puberty, unspecified	0.018	0.982	0.000
E30.8 Other disorders of puberty	0.018	0.982	0.000
E30.1 Precocious puberty	0.018	0.982	0.000
E30.0 Delayed puberty	0.018	0.982	0.000
E31.9 Polyglandular dysfunction, unspecified	0.018	0.982	0.000
E31.8 Other polyglandular dysfunction	0.018	0.982	0.000
E31.1 Polyglandular hyperfunction	0.018	0.982	0.000
E31.0 Autoimmune polyglandular failure	0.018	0.982	0.000
E32.9 Disease of thymus, unspecified	0.018	0.982	0.000
E32.8 Other diseases of thymus	0.018	0.982	0.000
E32.1 Abscess of thymus	0.018	0.982	0.000
E32.0 Persistent hyperplasia of thymus	0.018	0.982	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.018	0.982	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.018	0.982	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.018	0.982	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.018	0.982	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.018	0.982	0.000
E45 Retarded development following protein-energy malnutrition	0.018	0.982	0.000
E43 Unspecified severe protein-energy malnutrition	0.018	0.982	0.000
E42 Marasmic kwashiorkor	0.018	0.982	0.000
E41 Nutritional marasmus	0.018	0.982	0.000
E40 Kwashiorkor	0.018	0.982	0.000
I72.2 Aneurysm of renal artery	0.018	0.982	0.000
I31 Other diseases of pericardium	0.018	0.982	0.000
I20.1 Angina pectoris with documented spasm	0.017	0.982	0.000
E20.8 Other hypoparathyroidism	0.017	0.982	0.000
E20.1 Pseudohypoparathyroidism	0.017	0.982	0.000
E20.0 Idiopathic hypoparathyroidism	0.017	0.982	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.018	0.982	0.000
I72.9 Aneurysm of unspecified site	0.017	0.983	0.000
E24.2 Drug-induced Cushing's syndrome	0.017	0.983	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.017	0.983	0.000
E50-E64 Other nutritional deficiencies	0.017	0.983	0.000
I79.1 Aortitis in diseases classified elsewhere	0.017	0.983	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.017	0.983	0.000
I72.3 Aneurysm of iliac artery	0.017	0.983	0.000
E25.9 Adrenogenital disorder, unspecified	0.017	0.983	0.000
E25.8 Other adrenogenital disorders	0.017	0.983	0.000
E20.9 Hypoparathyroidism, unspecified	0.017	0.983	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.017	0.983	0.000
I72.1 Aneurysm of artery of upper extremity	0.017	0.983	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.016	0.984	0.000
I42.5 Other restrictive cardiomyopathy	0.016	0.984	0.000
I42.4 Endocardial fibroelastosis	0.016	0.984	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.016	0.984	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.016	0.984	0.000
E27 Other disorders of adrenal gland	0.016	0.984	0.000
E16 Other disorders of pancreatic internal secretion	0.016	0.984	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.016	0.984	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.016	0.984	0.000
E26.9 Hyperaldosteronism, unspecified	0.015	0.985	0.000
E26.8 Other hyperaldosteronism	0.015	0.985	0.000
E26.1 Secondary hyperaldosteronism	0.015	0.985	0.000
E22 Hyperfunction of pituitary gland	0.015	0.985	0.000
I70.8 Atherosclerosis of other arteries	0.015	0.985	0.000
E24.8 Other Cushing's syndrome	0.015	0.985	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.015	0.985	0.000
E24.3 Ectopic ACTH syndrome	0.015	0.985	0.000
E24.1 Nelson's syndrome	0.015	0.985	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.015	0.985	0.000
I74 Arterial embolism and thrombosis	0.015	0.985	0.000
I95 Hypotension	0.015	0.985	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.015	0.985	0.000
I35.0 Aortic (valve) stenosis	0.015	0.985	0.000
E28.9 Ovarian dysfunction, unspecified	0.014	0.986	0.000
E28.8 Other ovarian dysfunction	0.014	0.986	0.000
E28.1 Androgen excess	0.014	0.986	0.000
E28.0 Oestrogen excess	0.014	0.986	0.000
Z03.3 Observation for suspected nervous system disorder	0.014	0.986	0.000
I31.1 Chronic constrictive pericarditis	0.014	0.986	0.000
E46 Unspecified protein-energy malnutrition	0.014	0.986	0.000
I42.0 Dilated cardiomyopathy	0.014	0.986	0.000
I42.6 Alcoholic cardiomyopathy	0.014	0.986	0.000
I42.2 Other hypertrophic cardiomyopathy	0.014	0.986	0.000
E67.8 Other specified hyperalimentation	0.014	0.986	0.000
E67.3 Hypervitaminosis D	0.014	0.986	0.000
E67.2 Megavitamin-B6 syndrome	0.014	0.986	0.000
E67.1 Hypercarotenaemia	0.014	0.986	0.000
E67.0 Hypervitaminosis A	0.014	0.986	0.000
I74.8 Embolism and thrombosis of other arteries	0.014	0.986	0.000
I70.0 Atherosclerosis of aorta	0.014	0.986	0.000
I72.4 Aneurysm of artery of lower extremity	0.014	0.986	0.000
I70.9 Generalised and unspecified atherosclerosis	0.013	0.986	0.000
E24.0 Pituitary-dependent Cushing's disease	0.013	0.987	0.000
I31.0 Chronic adhesive pericarditis	0.013	0.987	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.013	0.987	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.013	0.987	0.000
E27.2 Addisonian crisis	0.013	0.987	0.000
E44.1 Mild protein-energy malnutrition	0.013	0.987	0.000
E44.0 Moderate protein-energy malnutrition	0.013	0.987	0.000
I72.8 Aneurysm of other specified arteries	0.013	0.987	0.000
I31.8 Other specified diseases of pericardium	0.013	0.987	0.000
I31.2 Haemopericardium, not elsewhere classified	0.013	0.987	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.013	0.987	0.000
I50.9 Heart failure, unspecified	0.013	0.987	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.013	0.987	0.000
E63 Other nutritional deficiencies	0.013	0.987	0.000
E56 Other vitamin deficiencies	0.013	0.987	0.000
E50 Vitamin A deficiency	0.013	0.987	0.000
E60 Dietary zinc deficiency	0.013	0.987	0.000
E59 Dietary selenium deficiency	0.013	0.987	0.000
E58 Dietary calcium deficiency	0.013	0.987	0.000
E54 Ascorbic acid deficiency	0.013	0.987	0.000
E52 Niacin deficiency [pellagra]	0.013	0.987	0.000
E61 Deficiency of other nutrient elements	0.013	0.987	0.000
E28.2 Polycystic ovarian syndrome	0.012	0.988	0.000
I72.0 Aneurysm of carotid artery	0.012	0.988	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations