TreeWAS – Variant ID: rs7907139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
I60-I69 Cerebrovascular diseases	0.998	0.002	0.000
Chapter IX Diseases of the circulatory system	0.998	0.002	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.998	0.002	0.000
Chapter VI Diseases of the nervous system	0.997	0.003	0.000
Chapter V Mental and behavioural disorders	0.991	0.009	0.000
M47 Spondylosis	0.990	0.010	0.000
M48 Other spondylopathies	0.986	0.014	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.985	0.015	0.000
D50-D53 Nutritional anaemias	0.984	0.016	0.000
M48.0 Spinal stenosis	0.979	0.021	0.000
I63 Cerebral infarction	0.976	0.024	0.000
M15-M19 Arthrosis	0.974	0.026	0.000
D50 Iron deficiency anaemia	0.971	0.029	0.000
I67 Other cerebrovascular diseases	0.964	0.036	0.000
M50-M54 Other dorsopathies	0.962	0.038	0.000
M19 Other arthrosis	0.961	0.039	0.000
D50.8 Other iron deficiency anaemias	0.959	0.041	0.000
Chapter VII Diseases of the eye and adnexa	0.956	0.044	0.000
M19.9 Arthrosis, unspecified	0.952	0.048	0.000
M48.06 Spinal stenosis (Lumbar region)	0.952	0.048	0.000
Q60-Q64 Congenital malformations of the urinary system	0.947	0.053	0.000
I30-I52 Other forms of heart disease	0.936	0.064	0.000
F30-F39 Mood [affective] disorders	0.934	0.066	0.000
D80-D89 Certain disorders involving the immune mechanism	0.934	0.066	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.933	0.067	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.932	0.068	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.925	0.075	0.000
H30-H36 Disorders of choroid and retina	0.922	0.078	0.000
M54 Dorsalgia	0.921	0.079	0.000
M70-M79 Other soft tissue disorders	0.918	0.082	0.000
Q61 Cystic kidney disease	0.916	0.084	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.913	0.087	0.000
M47.8 Other spondylosis	0.911	0.089	0.000
H33 Retinal detachments and breaks	0.911	0.089	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.911	0.089	0.000
I69 Sequelae of cerebrovascular disease	0.911	0.089	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.908	0.092	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.907	0.093	0.000
M47.9 Spondylosis, unspecified	0.907	0.093	0.000
G40-G47 Episodic and paroxysmal disorders	0.907	0.093	0.000
I67.1 Cerebral aneurysm, nonruptured	0.903	0.097	0.000
M19.94 Arthrosis, unspecified (Hand)	0.903	0.097	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.901	0.099	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.895	0.105	0.000
M47.1 Other spondylosis with myelopathy	0.893	0.107	0.000
H33.2 Serous retinal detachment	0.892	0.108	0.000
I35 Nonrheumatic aortic valve disorders	0.888	0.112	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.887	0.113	0.000
I63.8 Other cerebral infarction	0.884	0.116	0.000
I42 Cardiomyopathy	0.882	0.118	0.000
O42 Premature rupture of membranes	0.880	0.120	0.000
G20-G26 Extrapyramidal and movement disorders	0.878	0.122	0.000
I67.2 Cerebral atherosclerosis	0.877	0.123	0.000
D86 Sarcoidosis	0.875	0.125	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.874	0.126	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.874	0.126	0.000
F31 Bipolar affective disorder	0.872	0.128	0.000
I63.9 Cerebral infarction, unspecified	0.872	0.128	0.000
F41 Other anxiety disorders	0.860	0.140	0.000
I35.1 Aortic (valve) insufficiency	0.858	0.142	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.853	0.147	0.000
M54.5 Low back pain	0.853	0.147	0.000
G44 Other headache syndromes	0.853	0.147	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.849	0.151	0.000
Q61.0 Congenital single renal cyst	0.846	0.154	0.000
I65.2 Occlusion and stenosis of carotid artery	0.842	0.158	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.842	0.158	0.000
D50.9 Iron deficiency anaemia, unspecified	0.841	0.159	0.000
M48.09 Spinal stenosis (Site unspecified)	0.841	0.159	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.839	0.161	0.000
G81 Hemiplegia	0.836	0.164	0.000
M91-M94 Chondropathies	0.836	0.164	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.834	0.166	0.000
I44 Atrioventricular and left bundle-branch block	0.832	0.168	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.831	0.169	0.000
H55-H59 Other disorders of eye and adnexa	0.828	0.172	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.827	0.173	0.000
M60-M63 Disorders of muscles	0.825	0.175	0.000
F41.9 Anxiety disorder, unspecified	0.824	0.176	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.824	0.176	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.824	0.176	0.000
D68 Other coagulation defects	0.824	0.176	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.823	0.177	0.000
F31.9 Bipolar affective disorder, unspecified	0.821	0.179	0.000
M51 Other intervertebral disk disorders	0.820	0.180	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.818	0.182	0.000
H43-H45 Disorders of vitreous body and globe	0.816	0.184	0.000
G20 Parkinson's disease	0.816	0.184	0.000
Chapter XX External causes of morbidity and mortality	0.815	0.185	0.000
I46 Cardiac arrest	0.812	0.188	0.000
M79.2 Neuralgia and neuritis, unspecified	0.810	0.190	0.000
O00-O08 Pregnancy with abortive outcome	0.810	0.190	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.805	0.195	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.804	0.196	0.000
I67.9 Cerebrovascular disease, unspecified	0.803	0.197	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.803	0.197	0.000
Q61.2 Polycystic kidney, adult type	0.802	0.198	0.000
M54.57 Low back pain (Lumbosacral region)	0.802	0.198	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.801	0.199	0.000
H53-H54 Visual disturbances and blindness	0.797	0.203	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.796	0.204	0.000
I26 Pulmonary embolism	0.796	0.204	0.000
F33 Recurrent depressive disorder	0.796	0.204	0.000
H33.0 Retinal detachment with retinal break	0.794	0.206	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.793	0.206	0.000
D86.9 Sarcoidosis, unspecified	0.793	0.207	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.793	0.207	0.000
I42.9 Cardiomyopathy, unspecified	0.792	0.208	0.000
M47.86 Other spondylosis (Lumbar region)	0.783	0.217	0.000
G81.9 Hemiplegia, unspecified	0.782	0.218	0.000
F60-F69 Disorders of adult personality and behaviour	0.780	0.220	0.000
Q80-Q89 Other congenital malformations	0.779	0.221	0.000
M18 Arthrosis of first carpometacarpal joint	0.778	0.222	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.776	0.224	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.776	0.224	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.775	0.225	0.000
M54.2 Cervicalgia	0.774	0.226	0.000
I60 Subarachnoid haemorrhage	0.773	0.227	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.773	0.227	0.000
M46 Other inflammatory spondylopathies	0.772	0.228	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.772	0.228	0.000
I44.7 Left bundle-branch block, unspecified	0.768	0.232	0.000
H10-H13 Disorders of conjunctiva	0.764	0.236	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.763	0.237	0.000
I62 Other nontraumatic intracranial haemorrhage	0.763	0.237	0.000
F03 Unspecified dementia	0.761	0.239	0.000
M19.0 Primary arthrosis of other joints	0.760	0.240	0.000
I35.0 Aortic (valve) stenosis	0.759	0.241	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.758	0.242	0.000
D84 Other immunodeficiencies	0.758	0.242	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.756	0.244	0.000
G00 Bacterial meningitis, not elsewhere classified	0.755	0.245	0.000
M51.2 Other specified intervertebral disk displacement	0.754	0.246	0.000
D52 Folate deficiency anaemia	0.754	0.246	0.000
D53 Other nutritional anaemias	0.754	0.246	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.753	0.247	0.000
I69.3 Sequelae of cerebral infarction	0.751	0.249	0.000
O42.9 Premature rupture of membranes, unspecified	0.751	0.249	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.750	0.250	0.000
F39 Unspecified mood [affective] disorder	0.748	0.252	0.000
M79.0 Rheumatism, unspecified	0.746	0.254	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.746	0.254	0.000
M54.9 Dorsalgia, unspecified	0.746	0.254	0.000
H33.4 Traction detachment of retina	0.745	0.255	0.000
M45 Ankylosing spondylitis	0.745	0.255	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.744	0.256	0.000
M79.7 Fibromyalgia	0.744	0.256	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.743	0.257	0.000
M79.1 Myalgia	0.742	0.258	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.742	0.258	0.000
D68.2 Hereditary deficiency of other clotting factors	0.740	0.260	0.000
Q00-Q07 Congenital malformations of the nervous system	0.738	0.262	0.000
M79.8 Other specified soft tissue disorders	0.738	0.262	0.000
M47.2 Other spondylosis with radiculopathy	0.737	0.263	0.000
F99-F99 Unspecified mental disorder	0.733	0.267	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.732	0.268	0.000
G83 Other paralytic syndromes	0.731	0.269	0.000
O40 Polyhydramnios	0.728	0.272	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.728	0.272	0.000
Q61.3 Polycystic kidney, unspecified	0.727	0.273	0.000
F34 Persistent mood [affective] disorders	0.726	0.274	0.000
I46.0 Cardiac arrest with successful resuscitation	0.726	0.274	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.725	0.275	0.000
G45.3 Amaurosis fugax	0.723	0.277	0.000
D75 Other diseases of blood and blood-forming organs	0.722	0.278	0.000
I33 Acute and subacute endocarditis	0.721	0.278	0.000
D86.0 Sarcoidosis of lung	0.721	0.279	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.721	0.279	0.000
O44 Placenta praevia	0.720	0.280	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.719	0.281	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.717	0.283	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.716	0.284	0.000
F44 Dissociative [conversion] disorders	0.716	0.284	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.716	0.284	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.716	0.284	0.000
I00-I02 Acute rheumatic fever	0.716	0.284	0.000
D55-D59 Haemolytic anaemias	0.716	0.284	0.000
F43 Reaction to severe stress, and adjustment disorders	0.714	0.286	0.000
I71 Aortic aneurysm and dissection	0.714	0.286	0.000
M71 Other bursopathies	0.713	0.287	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.711	0.289	0.000
F70-F79 Mental retardation	0.711	0.289	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.709	0.290	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.709	0.291	0.000
I42.0 Dilated cardiomyopathy	0.709	0.291	0.000
I38 Endocarditis, valve unspecified	0.708	0.292	0.000
M48.9 Spondylopathy, unspecified	0.707	0.293	0.000
M48.8 Other specified spondylopathies	0.707	0.293	0.000
M48.4 Fatigue fracture of vertebra	0.707	0.293	0.000
M48.3 Traumatic spondylopathy	0.707	0.293	0.000
M48.2 Kissing spine	0.707	0.293	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.707	0.293	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.706	0.293	0.000
Q35-Q37 Cleft lip and cleft palate	0.706	0.293	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.706	0.293	0.000
I27 Other pulmonary heart diseases	0.706	0.293	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.706	0.294	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.706	0.294	0.000
G30-G32 Other degenerative diseases of the nervous system	0.704	0.296	0.000
I44.2 Atrioventricular block, complete	0.704	0.296	0.000
M00-M03 Infectious arthropathies	0.703	0.297	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.702	0.298	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.702	0.298	0.000
M48.04 Spinal stenosis (Thoracic region)	0.702	0.298	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.702	0.298	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.702	0.298	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.702	0.298	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.702	0.298	0.000
G03 Meningitis due to other and unspecified causes	0.700	0.299	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.700	0.300	0.000
M54.1 Radiculopathy	0.700	0.300	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.699	0.300	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.699	0.300	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.699	0.300	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.699	0.301	0.000
M62 Other disorders of muscle	0.699	0.301	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.699	0.301	0.000
M15 Polyarthrosis	0.698	0.302	0.000
D50.1 Sideropenic dysphagia	0.696	0.304	0.000
H44 Disorders of globe	0.696	0.304	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.696	0.304	0.000
M54.50 Low back pain (Multiple sites in spine)	0.694	0.306	0.000
H54 Blindness and low vision	0.693	0.307	0.000
H55 Nystagmus and other irregular eye movements	0.692	0.308	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.691	0.309	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.691	0.309	0.000
I67.5 Moyamoya disease	0.691	0.309	0.000
I67.4 Hypertensive encephalopathy	0.691	0.309	0.000
I67.3 Progressive vascular leukoencephalopathy	0.691	0.309	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.691	0.309	0.000
I42.2 Other hypertrophic cardiomyopathy	0.691	0.309	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.690	0.310	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.690	0.310	0.000
M19.8 Other specified arthrosis	0.689	0.311	0.000
M19.2 Other secondary arthrosis	0.689	0.311	0.000
H31 Other disorders of choroid	0.689	0.311	0.000
O85-O92 Complications predominantly related to the puerperium	0.688	0.312	0.000
G90-G99 Other disorders of the nervous system	0.687	0.313	0.000
H33.3 Retinal breaks without detachment	0.685	0.315	0.000
M53 Other dorsopathies, not elsewhere classified	0.685	0.315	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.684	0.316	0.000
D80 Immunodeficiency with predominantly antibody defects	0.683	0.317	0.000
M54.6 Pain in thoracic spine	0.683	0.317	0.000
M51.4 Schmorl's nodes	0.682	0.318	0.000
D73 Diseases of spleen	0.681	0.319	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.681	0.319	0.000
F11 Mental and behavioural disorders due to use of opioids	0.680	0.320	0.000
Q64 Other congenital malformations of urinary system	0.679	0.321	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.679	0.321	0.000
O32.4 Maternal care for high head at term	0.679	0.321	0.000
O32.0 Maternal care for unstable lie	0.677	0.323	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.676	0.324	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.674	0.326	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.673	0.326	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.673	0.327	0.000
M92 Other juvenile osteochondrosis	0.673	0.327	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.672	0.328	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.672	0.328	0.000
G44.0 Cluster headache syndrome	0.672	0.328	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.672	0.328	0.000
O80-O84 Delivery	0.672	0.328	0.000
G44.8 Other specified headache syndromes	0.671	0.329	0.000
M72 Fibroblastic disorders	0.671	0.329	0.000
I52 Other heart disorders in diseases classified elsewhere	0.671	0.329	0.000
I48 Atrial fibrillation and flutter	0.671	0.329	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.671	0.329	0.000
I41 Myocarditis in diseases classified elsewhere	0.671	0.329	0.000
I40 Acute myocarditis	0.671	0.329	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.671	0.329	0.000
I36 Nonrheumatic tricuspid valve disorders	0.671	0.329	0.000
I32 Pericarditis in diseases classified elsewhere	0.671	0.329	0.000
F38 Other mood [affective] disorders	0.670	0.330	0.000
D83 Common variable immunodeficiency	0.669	0.330	0.000
D82 Immunodeficiency associated with other major defects	0.669	0.330	0.000
D81 Combined immunodeficiencies	0.669	0.330	0.000
D69 Purpura and other haemorrhagic conditions	0.669	0.331	0.000
F00 Dementia in Alzheimer's disease	0.669	0.331	0.000
O03 Spontaneous abortion	0.669	0.331	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.668	0.332	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.667	0.332	0.000
O02 Other abnormal products of conception	0.666	0.334	0.000
M86-M90 Other osteopathies	0.666	0.334	0.000
F30 Manic episode	0.664	0.336	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.663	0.337	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.663	0.337	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.663	0.337	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.663	0.337	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.663	0.337	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.663	0.337	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.662	0.337	0.000
D86.8 Sarcoidosis of other and combined sites	0.662	0.338	0.000
H20 Iridocyclitis	0.661	0.339	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.661	0.339	0.000
H30 Chorioretinal inflammation	0.661	0.339	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.660	0.339	0.000
M54.8 Other dorsalgia	0.660	0.339	0.000
M54.0 Panniculitis affecting regions of neck and back	0.660	0.339	0.000
O36 Maternal care for other known or suspected foetal problems	0.659	0.341	0.000
Y00-Y09 Assault	0.659	0.341	0.000
O48 Prolonged pregnancy	0.658	0.342	0.000
G82 Paraplegia and tetraplegia	0.658	0.342	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.658	0.342	0.000
X50-X57 Overexertion, travel and privation	0.657	0.343	0.000
Q61.9 Cystic kidney disease, unspecified	0.657	0.343	0.000
Q61.8 Other cystic kidney diseases	0.657	0.343	0.000
Q61.5 Medullary cystic kidney	0.657	0.343	0.000
Q61.4 Renal dysplasia	0.657	0.343	0.000
Q61.1 Polycystic kidney, infantile type	0.657	0.343	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.656	0.344	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.655	0.345	0.000
I44.3 Other and unspecified atrioventricular block	0.654	0.346	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.653	0.346	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.653	0.346	0.000
M47.84 Other spondylosis (Thoracic region)	0.653	0.346	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.653	0.346	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.653	0.346	0.000
Q50-Q56 Congenital malformations of genital organs	0.653	0.346	0.000
I35.8 Other aortic valve disorders	0.653	0.347	0.000
F48 Other neurotic disorders	0.653	0.347	0.000
I42.6 Alcoholic cardiomyopathy	0.653	0.347	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.653	0.347	0.000
M40-M43 Deforming dorsopathies	0.653	0.347	0.000
Q43 Other congenital malformations of intestine	0.653	0.347	0.000
M54.56 Low back pain (Lumbar region)	0.653	0.347	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.652	0.348	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.651	0.349	0.000
O45 Premature separation of placenta [abruptio placentae]	0.651	0.349	0.000
O33 Maternal care for known or suspected disproportion	0.651	0.349	0.000
O31 Complications specific to multiple gestation	0.651	0.349	0.000
D51 Vitamin B12 deficiency anaemia	0.651	0.349	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.650	0.349	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.650	0.349	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.650	0.349	0.000
I65.1 Occlusion and stenosis of basilar artery	0.650	0.349	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.650	0.349	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.650	0.350	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.650	0.350	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.650	0.350	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.650	0.350	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.650	0.350	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.650	0.350	0.000
G24 Dystonia	0.650	0.350	0.000
M54.22 Cervicalgia (Cervical region)	0.650	0.350	0.000
M76 Enthesopathies of lower limb, excluding foot	0.648	0.352	0.000
E50-E64 Other nutritional deficiencies	0.648	0.352	0.000
O30 Multiple gestation	0.647	0.353	0.000
F80-F89 Disorders of psychological development	0.647	0.353	0.000
D67 Hereditary factor IX deficiency	0.646	0.354	0.000
D66 Hereditary factor VIII deficiency	0.646	0.354	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.646	0.354	0.000
M47.89 Other spondylosis (Site unspecified)	0.645	0.355	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.644	0.356	0.000
H33.1 Retinoschisis and retinal cysts	0.644	0.356	0.000
Chapter XXII Codes for special purposes	0.643	0.356	0.000
G41 Status epilepticus	0.642	0.358	0.000
I28 Other diseases of pulmonary vessels	0.642	0.358	0.000
O04 Medical abortion	0.642	0.358	0.000
I37 Pulmonary valve disorders	0.641	0.359	0.000
H11 Other disorders of conjunctiva	0.641	0.359	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.640	0.359	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.640	0.359	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.640	0.359	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.640	0.359	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.640	0.359	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.640	0.359	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.640	0.359	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.640	0.359	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.640	0.359	0.000
G70-G73 Diseases of myoneural junction and muscle	0.640	0.360	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.640	0.360	0.000
I30 Acute pericarditis	0.639	0.361	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.638	0.361	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.638	0.362	0.000
M94 Other disorders of cartilage	0.637	0.362	0.000
M65-M68 Disorders of synovium and tendon	0.638	0.362	0.000
I27.0 Primary pulmonary hypertension	0.637	0.363	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.637	0.363	0.000
D86.1 Sarcoidosis of lymph nodes	0.637	0.363	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.636	0.363	0.000
M79.9 Soft tissue disorder, unspecified	0.636	0.364	0.000
M79.3 Panniculitis, unspecified	0.636	0.364	0.000
G44.2 Tension-type headache	0.636	0.364	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.635	0.364	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.635	0.365	0.000
F41.1 Generalised anxiety disorder	0.634	0.366	0.000
M48.02 Spinal stenosis (Cervical region)	0.634	0.366	0.000
G00.9 Bacterial meningitis, unspecified	0.633	0.367	0.000
G35 Multiple sclerosis	0.633	0.367	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.632	0.367	0.000
I42.5 Other restrictive cardiomyopathy	0.632	0.367	0.000
I42.4 Endocardial fibroelastosis	0.632	0.367	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.632	0.367	0.000
M93 Other osteochondropathies	0.632	0.368	0.000
D84.1 Defects in the complement system	0.632	0.368	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.631	0.369	0.000
M70.6 Trochanteric bursitis	0.630	0.369	0.000
G23 Other degenerative diseases of basal ganglia	0.630	0.370	0.000
G21 Secondary Parkinsonism	0.630	0.370	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.630	0.370	0.000
G22 Parkinsonism in diseases classified elsewhere	0.630	0.370	0.000
D68.8 Other specified coagulation defects	0.629	0.371	0.000
I50 Heart failure	0.628	0.372	0.000
D86.3 Sarcoidosis of skin	0.627	0.373	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.627	0.373	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.627	0.373	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.627	0.373	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.627	0.373	0.000
G45.0 Vertebro-basilar artery syndrome	0.627	0.373	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.626	0.374	0.000
F02 Dementia in other diseases classified elsewhere	0.626	0.374	0.000
F09 Unspecified organic or symptomatic mental disorder	0.626	0.374	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.626	0.374	0.000
D75.1 Secondary polycythaemia	0.626	0.374	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.626	0.374	0.000
I71.0 Dissection of aorta [any part]	0.626	0.374	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.626	0.374	0.000
F31.8 Other bipolar affective disorders	0.625	0.375	0.000
F31.7 Bipolar affective disorder, currently in remission	0.625	0.375	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.625	0.375	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.625	0.375	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.625	0.375	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.625	0.375	0.000
M17 Gonarthrosis [arthrosis of knee]	0.625	0.375	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.624	0.375	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.624	0.376	0.000
H43 Disorders of vitreous body	0.624	0.376	0.000
M79.10 Myalgia (Multiple sites)	0.624	0.376	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.622	0.377	0.000
W20-W49 Exposure to inanimate mechanical forces	0.622	0.378	0.000
H54.7 Unspecified visual loss	0.621	0.379	0.000
Q21 Congenital malformations of cardiac septa	0.621	0.379	0.000
W50-W64 Exposure to animate mechanical forces	0.620	0.380	0.000
M54.59 Low back pain (Site unspecified)	0.620	0.380	0.000
Q63 Other congenital malformations of kidney	0.620	0.380	0.000
M50 Cervical disk disorders	0.619	0.381	0.000
Q60.0 Renal agenesis, unilateral	0.619	0.381	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.619	0.381	0.000
F33.9 Recurrent depressive disorder, unspecified	0.618	0.382	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.618	0.382	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.618	0.382	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.618	0.382	0.000
G80 Infantile cerebral palsy	0.617	0.382	0.000
I31 Other diseases of pericardium	0.617	0.383	0.000
F41.8 Other specified anxiety disorders	0.617	0.383	0.000
F41.3 Other mixed anxiety disorders	0.617	0.383	0.000
O41 Other disorders of amniotic fluid and membranes	0.616	0.384	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.615	0.385	0.000
F01 Vascular dementia	0.614	0.386	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.614	0.386	0.000
M54.55 Low back pain (Thoracolumbar region)	0.612	0.388	0.000
M54.54 Low back pain-Thoracic	0.612	0.388	0.000
M54.53 Low back pain-Cervicothoracic	0.612	0.388	0.000
M54.52 Low back pain-Cervical	0.612	0.388	0.000
M54.51 Low back pain-Occipit-atl-axl	0.612	0.388	0.000
G44.3 Chronic posttraumatic headache	0.611	0.389	0.000
G44.1 Vascular headache, not elsewhere classified	0.611	0.389	0.000
F17.1 Harmful use	0.611	0.389	0.000
H44.2 Degenerative myopia	0.610	0.390	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.610	0.390	0.000
M79.70 Fibromyalgia (Multiple sites)	0.609	0.390	0.000
M62.8 Other specified disorders of muscle	0.609	0.391	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.608	0.392	0.000
I47 Paroxysmal tachycardia	0.608	0.392	0.000
D68.6 Other Thrombophilia	0.607	0.393	0.000
M54.4 Lumbago with sciatica	0.607	0.393	0.000
D68.9 Coagulation defect, unspecified	0.607	0.393	0.000
F60 Specific personality disorders	0.606	0.394	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.606	0.394	0.000
M54.3 Sciatica	0.605	0.395	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.605	0.395	0.000
F42 Obsessive-compulsive disorder	0.603	0.397	0.000
E40-E46 Malnutrition	0.603	0.397	0.000
G52 Disorders of other cranial nerves	0.602	0.398	0.000
M19.1 Posttraumatic arthrosis of other joints	0.600	0.399	0.000
X20-X29 Contact with venomous animals and plants	0.600	0.400	0.000
Y65 Other misadventures during surgical and medical care	0.600	0.400	0.000
G81.1 Spastic hemiplegia	0.600	0.400	0.000
G81.0 Flaccid hemiplegia	0.600	0.400	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.599	0.400	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.599	0.401	0.000
F45 Somatoform disorders	0.599	0.401	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.599	0.401	0.000
H34 Retinal vascular occlusions	0.598	0.402	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.598	0.402	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.598	0.402	0.000
I44.5 Left posterior fascicular block	0.596	0.404	0.000
I44.4 Left anterior fascicular block	0.596	0.404	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.596	0.404	0.000
H54.0 Blindness, both eyes	0.594	0.406	0.000
E61 Deficiency of other nutrient elements	0.594	0.406	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.593	0.406	0.001
H18 Other disorders of cornea	0.593	0.407	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.592	0.408	0.000
H16 Keratitis	0.592	0.408	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations